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Network neighborhood for query Sequence : SH24A_MOUSE

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SH24A_MOUSE
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SH24A_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	326	Target Neighborhood Hits	326	Shared Neighborhood Hits	326
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

SH24A_HUMAN
θ value	4.39142e-172 (rank : 2)	NC score	0.829632 (rank : 2)
Query Neighborhood Hits	326	Target Neighborhood Hits	455	Shared Neighborhood Hits	194
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

HSH2D_MOUSE
θ value	5.25075e-16 (rank : 3)	NC score	0.616340 (rank : 3)
Query Neighborhood Hits	326	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HSH2D_HUMAN
θ value	9.90251e-15 (rank : 4)	NC score	0.604287 (rank : 4)
Query Neighborhood Hits	326	Target Neighborhood Hits	159	Shared Neighborhood Hits	83
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

SH22A_MOUSE
θ value	2.98157e-11 (rank : 5)	NC score	0.544818 (rank : 5)
Query Neighborhood Hits	326	Target Neighborhood Hits	179	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH22A_HUMAN
θ value	4.30538e-10 (rank : 6)	NC score	0.529761 (rank : 6)
Query Neighborhood Hits	326	Target Neighborhood Hits	144	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

RBMX2_HUMAN
θ value	4.92598e-06 (rank : 7)	NC score	0.102916 (rank : 370)
Query Neighborhood Hits	326	Target Neighborhood Hits	351	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y388, Q5JY82, Q9Y3I8	Gene names	RBMX2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

SHD_MOUSE
θ value	8.40245e-06 (rank : 8)	NC score	0.443241 (rank : 7)
Query Neighborhood Hits	326	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

PTN6_MOUSE
θ value	1.87187e-05 (rank : 9)	NC score	0.187154 (rank : 62)
Query Neighborhood Hits	326	Target Neighborhood Hits	225	Shared Neighborhood Hits	90
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

DAPP1_HUMAN
θ value	3.19293e-05 (rank : 10)	NC score	0.385807 (rank : 10)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	5.44631e-05 (rank : 11)	NC score	0.379399 (rank : 11)
Query Neighborhood Hits	326	Target Neighborhood Hits	225	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

SHD_HUMAN
θ value	5.44631e-05 (rank : 12)	NC score	0.422888 (rank : 8)
Query Neighborhood Hits	326	Target Neighborhood Hits	204	Shared Neighborhood Hits	89
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

ABL1_HUMAN
θ value	7.1131e-05 (rank : 13)	NC score	0.156909 (rank : 85)
Query Neighborhood Hits	326	Target Neighborhood Hits	1220	Shared Neighborhood Hits	116
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	7.1131e-05 (rank : 14)	NC score	0.156444 (rank : 86)
Query Neighborhood Hits	326	Target Neighborhood Hits	1178	Shared Neighborhood Hits	110
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

PLCG1_HUMAN
θ value	0.000121331 (rank : 15)	NC score	0.311538 (rank : 23)
Query Neighborhood Hits	326	Target Neighborhood Hits	293	Shared Neighborhood Hits	87
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	0.000121331 (rank : 16)	NC score	0.309842 (rank : 24)
Query Neighborhood Hits	326	Target Neighborhood Hits	314	Shared Neighborhood Hits	88
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

ABL2_HUMAN
θ value	0.00020696 (rank : 17)	NC score	0.157121 (rank : 84)
Query Neighborhood Hits	326	Target Neighborhood Hits	1045	Shared Neighborhood Hits	107
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

GRB2_MOUSE
θ value	0.00020696 (rank : 18)	NC score	0.300437 (rank : 27)
Query Neighborhood Hits	326	Target Neighborhood Hits	312	Shared Neighborhood Hits	92
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

PTN11_HUMAN
θ value	0.000270298 (rank : 19)	NC score	0.208099 (rank : 60)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	89
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	0.000270298 (rank : 20)	NC score	0.208123 (rank : 59)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	89
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

GRB2_HUMAN
θ value	0.00035302 (rank : 21)	NC score	0.298536 (rank : 28)
Query Neighborhood Hits	326	Target Neighborhood Hits	310	Shared Neighborhood Hits	90
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

SHE_HUMAN
θ value	0.000602161 (rank : 22)	NC score	0.386745 (rank : 9)
Query Neighborhood Hits	326	Target Neighborhood Hits	164	Shared Neighborhood Hits	85
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

TRHY_HUMAN
θ value	0.000602161 (rank : 23)	NC score	0.141134 (rank : 116)
Query Neighborhood Hits	326	Target Neighborhood Hits	1385	Shared Neighborhood Hits	131
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

BRE1A_HUMAN
θ value	0.000786445 (rank : 24)	NC score	0.124243 (rank : 202)
Query Neighborhood Hits	326	Target Neighborhood Hits	1071	Shared Neighborhood Hits	114
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

KSYK_MOUSE
θ value	0.000786445 (rank : 25)	NC score	0.140704 (rank : 117)
Query Neighborhood Hits	326	Target Neighborhood Hits	944	Shared Neighborhood Hits	95
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

APS_HUMAN
θ value	0.00102713 (rank : 26)	NC score	0.362254 (rank : 13)
Query Neighborhood Hits	326	Target Neighborhood Hits	162	Shared Neighborhood Hits	83
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

FER_HUMAN
θ value	0.00102713 (rank : 27)	NC score	0.150688 (rank : 97)
Query Neighborhood Hits	326	Target Neighborhood Hits	1278	Shared Neighborhood Hits	175
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

SHC1_HUMAN
θ value	0.00102713 (rank : 28)	NC score	0.297049 (rank : 30)
Query Neighborhood Hits	326	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	0.00102713 (rank : 29)	NC score	0.303654 (rank : 25)
Query Neighborhood Hits	326	Target Neighborhood Hits	180	Shared Neighborhood Hits	87
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

PTK6_MOUSE
θ value	0.00175202 (rank : 30)	NC score	0.136238 (rank : 131)
Query Neighborhood Hits	326	Target Neighborhood Hits	1026	Shared Neighborhood Hits	94
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

RASA1_HUMAN
θ value	0.00175202 (rank : 31)	NC score	0.301798 (rank : 26)
Query Neighborhood Hits	326	Target Neighborhood Hits	258	Shared Neighborhood Hits	88
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

PTK6_HUMAN
θ value	0.00228821 (rank : 32)	NC score	0.134860 (rank : 135)
Query Neighborhood Hits	326	Target Neighborhood Hits	1020	Shared Neighborhood Hits	94
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

MAP1A_HUMAN
θ value	0.00298849 (rank : 33)	NC score	0.181721 (rank : 63)
Query Neighborhood Hits	326	Target Neighborhood Hits	1626	Shared Neighborhood Hits	183
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

GRAP2_HUMAN
θ value	0.00509761 (rank : 34)	NC score	0.297392 (rank : 29)
Query Neighborhood Hits	326	Target Neighborhood Hits	304	Shared Neighborhood Hits	89
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

KSYK_HUMAN
θ value	0.00509761 (rank : 35)	NC score	0.138654 (rank : 126)
Query Neighborhood Hits	326	Target Neighborhood Hits	901	Shared Neighborhood Hits	95
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

MAP9_HUMAN
θ value	0.00509761 (rank : 36)	NC score	0.173997 (rank : 70)
Query Neighborhood Hits	326	Target Neighborhood Hits	518	Shared Neighborhood Hits	88
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

SFR12_HUMAN
θ value	0.00509761 (rank : 37)	NC score	0.164545 (rank : 78)
Query Neighborhood Hits	326	Target Neighborhood Hits	553	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

APS_MOUSE
θ value	0.00869519 (rank : 38)	NC score	0.317054 (rank : 20)
Query Neighborhood Hits	326	Target Neighborhood Hits	134	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

CSK_MOUSE
θ value	0.00869519 (rank : 39)	NC score	0.144075 (rank : 109)
Query Neighborhood Hits	326	Target Neighborhood Hits	1009	Shared Neighborhood Hits	103
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

P55G_HUMAN
θ value	0.00869519 (rank : 40)	NC score	0.323183 (rank : 18)
Query Neighborhood Hits	326	Target Neighborhood Hits	451	Shared Neighborhood Hits	149
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	0.00869519 (rank : 41)	NC score	0.319315 (rank : 19)
Query Neighborhood Hits	326	Target Neighborhood Hits	401	Shared Neighborhood Hits	144
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

CAF1A_HUMAN
θ value	0.0113563 (rank : 42)	NC score	0.152685 (rank : 91)
Query Neighborhood Hits	326	Target Neighborhood Hits	750	Shared Neighborhood Hits	101
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

IF2P_HUMAN
θ value	0.0113563 (rank : 43)	NC score	0.154167 (rank : 90)
Query Neighborhood Hits	326	Target Neighborhood Hits	889	Shared Neighborhood Hits	100
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

P85A_HUMAN
θ value	0.0113563 (rank : 44)	NC score	0.268854 (rank : 38)
Query Neighborhood Hits	326	Target Neighborhood Hits	479	Shared Neighborhood Hits	126
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SHE_MOUSE
θ value	0.0113563 (rank : 45)	NC score	0.377307 (rank : 12)
Query Neighborhood Hits	326	Target Neighborhood Hits	169	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SRMS_HUMAN
θ value	0.0113563 (rank : 46)	NC score	0.138956 (rank : 125)
Query Neighborhood Hits	326	Target Neighborhood Hits	946	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

CSK_HUMAN
θ value	0.0148317 (rank : 47)	NC score	0.142776 (rank : 111)
Query Neighborhood Hits	326	Target Neighborhood Hits	1009	Shared Neighborhood Hits	103
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

MY18A_MOUSE
θ value	0.0148317 (rank : 48)	NC score	0.146966 (rank : 102)
Query Neighborhood Hits	326	Target Neighborhood Hits	1989	Shared Neighborhood Hits	199
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SFRS4_MOUSE
θ value	0.0148317 (rank : 49)	NC score	0.084898 (rank : 540)
Query Neighborhood Hits	326	Target Neighborhood Hits	406	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SHB_MOUSE
θ value	0.0148317 (rank : 50)	NC score	0.340631 (rank : 14)
Query Neighborhood Hits	326	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SRMS_MOUSE
θ value	0.0148317 (rank : 51)	NC score	0.134456 (rank : 137)
Query Neighborhood Hits	326	Target Neighborhood Hits	964	Shared Neighborhood Hits	97
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

CCD46_HUMAN
θ value	0.0193708 (rank : 52)	NC score	0.156013 (rank : 87)
Query Neighborhood Hits	326	Target Neighborhood Hits	1430	Shared Neighborhood Hits	162
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

GRB7_MOUSE
θ value	0.0193708 (rank : 53)	NC score	0.252429 (rank : 44)
Query Neighborhood Hits	326	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

P85A_MOUSE
θ value	0.0193708 (rank : 54)	NC score	0.268360 (rank : 39)
Query Neighborhood Hits	326	Target Neighborhood Hits	435	Shared Neighborhood Hits	119
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	0.0193708 (rank : 55)	NC score	0.312459 (rank : 22)
Query Neighborhood Hits	326	Target Neighborhood Hits	543	Shared Neighborhood Hits	164
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

GOGB1_HUMAN
θ value	0.0252991 (rank : 56)	NC score	0.145492 (rank : 105)
Query Neighborhood Hits	326	Target Neighborhood Hits	2297	Shared Neighborhood Hits	194
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LNK_HUMAN
θ value	0.0252991 (rank : 57)	NC score	0.337124 (rank : 15)
Query Neighborhood Hits	326	Target Neighborhood Hits	151	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

PLEC1_HUMAN
θ value	0.0252991 (rank : 58)	NC score	0.095041 (rank : 429)
Query Neighborhood Hits	326	Target Neighborhood Hits	1326	Shared Neighborhood Hits	123
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SHB_HUMAN
θ value	0.0252991 (rank : 59)	NC score	0.336151 (rank : 16)
Query Neighborhood Hits	326	Target Neighborhood Hits	141	Shared Neighborhood Hits	85
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

KIF4A_HUMAN
θ value	0.0330416 (rank : 60)	NC score	0.120811 (rank : 217)
Query Neighborhood Hits	326	Target Neighborhood Hits	1159	Shared Neighborhood Hits	160
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MAP9_MOUSE
θ value	0.0330416 (rank : 61)	NC score	0.157389 (rank : 83)
Query Neighborhood Hits	326	Target Neighborhood Hits	529	Shared Neighborhood Hits	79
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

STK10_MOUSE
θ value	0.0330416 (rank : 62)	NC score	0.112273 (rank : 290)
Query Neighborhood Hits	326	Target Neighborhood Hits	2132	Shared Neighborhood Hits	214
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TRDN_HUMAN
θ value	0.0330416 (rank : 63)	NC score	0.119254 (rank : 228)
Query Neighborhood Hits	326	Target Neighborhood Hits	542	Shared Neighborhood Hits	71
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ZAP70_HUMAN
θ value	0.0330416 (rank : 64)	NC score	0.123313 (rank : 206)
Query Neighborhood Hits	326	Target Neighborhood Hits	893	Shared Neighborhood Hits	95
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

CN145_HUMAN
θ value	0.0431538 (rank : 65)	NC score	0.145558 (rank : 104)
Query Neighborhood Hits	326	Target Neighborhood Hits	1196	Shared Neighborhood Hits	156
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

GRAP2_MOUSE
θ value	0.0431538 (rank : 66)	NC score	0.289647 (rank : 31)
Query Neighborhood Hits	326	Target Neighborhood Hits	297	Shared Neighborhood Hits	88
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

RFC1_MOUSE
θ value	0.0431538 (rank : 67)	NC score	0.097376 (rank : 407)
Query Neighborhood Hits	326	Target Neighborhood Hits	290	Shared Neighborhood Hits	60
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

SMC2_MOUSE
θ value	0.0431538 (rank : 68)	NC score	0.134128 (rank : 142)
Query Neighborhood Hits	326	Target Neighborhood Hits	1131	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

TENS4_MOUSE
θ value	0.0431538 (rank : 69)	NC score	0.170987 (rank : 73)
Query Neighborhood Hits	326	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

ZAP70_MOUSE
θ value	0.0431538 (rank : 70)	NC score	0.124398 (rank : 197)
Query Neighborhood Hits	326	Target Neighborhood Hits	905	Shared Neighborhood Hits	97
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

FES_MOUSE
θ value	0.0563607 (rank : 71)	NC score	0.106015 (rank : 342)
Query Neighborhood Hits	326	Target Neighborhood Hits	980	Shared Neighborhood Hits	91
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FYN_HUMAN
θ value	0.0563607 (rank : 72)	NC score	0.138102 (rank : 129)
Query Neighborhood Hits	326	Target Neighborhood Hits	1078	Shared Neighborhood Hits	102
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

KIF4A_MOUSE
θ value	0.0563607 (rank : 73)	NC score	0.103536 (rank : 363)
Query Neighborhood Hits	326	Target Neighborhood Hits	1033	Shared Neighborhood Hits	140
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

LNK_MOUSE
θ value	0.0563607 (rank : 74)	NC score	0.330812 (rank : 17)
Query Neighborhood Hits	326	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

P85B_MOUSE
θ value	0.0563607 (rank : 75)	NC score	0.312955 (rank : 21)
Query Neighborhood Hits	326	Target Neighborhood Hits	519	Shared Neighborhood Hits	160
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

SFR12_MOUSE
θ value	0.0563607 (rank : 76)	NC score	0.144604 (rank : 107)
Query Neighborhood Hits	326	Target Neighborhood Hits	486	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

TAF3_MOUSE
θ value	0.0563607 (rank : 77)	NC score	0.128072 (rank : 169)
Query Neighborhood Hits	326	Target Neighborhood Hits	463	Shared Neighborhood Hits	76
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ATRX_HUMAN
θ value	0.0736092 (rank : 78)	NC score	0.120176 (rank : 221)
Query Neighborhood Hits	326	Target Neighborhood Hits	842	Shared Neighborhood Hits	117
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

RBBP6_HUMAN
θ value	0.0736092 (rank : 79)	NC score	0.159411 (rank : 81)
Query Neighborhood Hits	326	Target Neighborhood Hits	1135	Shared Neighborhood Hits	132
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CCD46_MOUSE
θ value	0.0961366 (rank : 80)	NC score	0.158986 (rank : 82)
Query Neighborhood Hits	326	Target Neighborhood Hits	1405	Shared Neighborhood Hits	178
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

FES_HUMAN
θ value	0.0961366 (rank : 81)	NC score	0.113269 (rank : 277)
Query Neighborhood Hits	326	Target Neighborhood Hits	978	Shared Neighborhood Hits	99
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

IF3A_HUMAN
θ value	0.0961366 (rank : 82)	NC score	0.151834 (rank : 95)
Query Neighborhood Hits	326	Target Neighborhood Hits	875	Shared Neighborhood Hits	128
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	0.0961366 (rank : 83)	NC score	0.148957 (rank : 100)
Query Neighborhood Hits	326	Target Neighborhood Hits	871	Shared Neighborhood Hits	123
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

MY18A_HUMAN
θ value	0.0961366 (rank : 84)	NC score	0.142211 (rank : 113)
Query Neighborhood Hits	326	Target Neighborhood Hits	1929	Shared Neighborhood Hits	198
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH10_MOUSE
θ value	0.0961366 (rank : 85)	NC score	0.107477 (rank : 332)
Query Neighborhood Hits	326	Target Neighborhood Hits	1612	Shared Neighborhood Hits	151
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NEST_HUMAN
θ value	0.0961366 (rank : 86)	NC score	0.139584 (rank : 122)
Query Neighborhood Hits	326	Target Neighborhood Hits	1305	Shared Neighborhood Hits	160
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PCLO_MOUSE
θ value	0.0961366 (rank : 87)	NC score	0.058630 (rank : 967)
Query Neighborhood Hits	326	Target Neighborhood Hits	2275	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TENS4_HUMAN
θ value	0.0961366 (rank : 88)	NC score	0.154310 (rank : 89)
Query Neighborhood Hits	326	Target Neighborhood Hits	214	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

MACOI_HUMAN
θ value	0.125558 (rank : 89)	NC score	0.117933 (rank : 243)
Query Neighborhood Hits	326	Target Neighborhood Hits	650	Shared Neighborhood Hits	95
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MYH10_HUMAN
θ value	0.125558 (rank : 90)	NC score	0.106385 (rank : 339)
Query Neighborhood Hits	326	Target Neighborhood Hits	1620	Shared Neighborhood Hits	151
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SFR17_HUMAN
θ value	0.125558 (rank : 91)	NC score	0.104672 (rank : 356)
Query Neighborhood Hits	326	Target Neighborhood Hits	325	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

ZN291_HUMAN
θ value	0.125558 (rank : 92)	NC score	0.127261 (rank : 178)
Query Neighborhood Hits	326	Target Neighborhood Hits	647	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

ATRX_MOUSE
θ value	0.163984 (rank : 93)	NC score	0.107921 (rank : 329)
Query Neighborhood Hits	326	Target Neighborhood Hits	682	Shared Neighborhood Hits	99
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CYLC2_HUMAN
θ value	0.163984 (rank : 94)	NC score	0.119998 (rank : 223)
Query Neighborhood Hits	326	Target Neighborhood Hits	223	Shared Neighborhood Hits	36
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DDX21_MOUSE
θ value	0.163984 (rank : 95)	NC score	0.029870 (rank : 1198)
Query Neighborhood Hits	326	Target Neighborhood Hits	350	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

EEA1_HUMAN
θ value	0.163984 (rank : 96)	NC score	0.122115 (rank : 211)
Query Neighborhood Hits	326	Target Neighborhood Hits	1796	Shared Neighborhood Hits	168
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

LCK_HUMAN
θ value	0.163984 (rank : 97)	NC score	0.129985 (rank : 159)
Query Neighborhood Hits	326	Target Neighborhood Hits	987	Shared Neighborhood Hits	93
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LEO1_HUMAN
θ value	0.163984 (rank : 98)	NC score	0.127754 (rank : 172)
Query Neighborhood Hits	326	Target Neighborhood Hits	958	Shared Neighborhood Hits	116
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

RENT2_HUMAN
θ value	0.163984 (rank : 99)	NC score	0.130575 (rank : 154)
Query Neighborhood Hits	326	Target Neighborhood Hits	618	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SON_HUMAN
θ value	0.163984 (rank : 100)	NC score	0.043476 (rank : 1175)
Query Neighborhood Hits	326	Target Neighborhood Hits	1568	Shared Neighborhood Hits	63
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CAF1A_MOUSE
θ value	0.21417 (rank : 101)	NC score	0.145864 (rank : 103)
Query Neighborhood Hits	326	Target Neighborhood Hits	736	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CD2L2_HUMAN
θ value	0.21417 (rank : 102)	NC score	0.061067 (rank : 931)
Query Neighborhood Hits	326	Target Neighborhood Hits	1439	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CRKL_MOUSE
θ value	0.21417 (rank : 103)	NC score	0.259951 (rank : 41)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	92
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CYLC1_HUMAN
θ value	0.21417 (rank : 104)	NC score	0.133771 (rank : 144)
Query Neighborhood Hits	326	Target Neighborhood Hits	408	Shared Neighborhood Hits	66
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

GBP4_HUMAN
θ value	0.21417 (rank : 105)	NC score	0.064243 (rank : 870)
Query Neighborhood Hits	326	Target Neighborhood Hits	484	Shared Neighborhood Hits	61
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

IGB1B_MOUSE
θ value	0.21417 (rank : 106)	NC score	0.055811 (rank : 1039)
Query Neighborhood Hits	326	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZ29	Gene names	Igbp1b
Domain Architecture
Description	Immunoglobulin-binding protein 1b (CD79a-binding protein 1b) (Alpha 4- b protein) (Alpha4-b).

LCK_MOUSE
θ value	0.21417 (rank : 107)	NC score	0.129156 (rank : 162)
Query Neighborhood Hits	326	Target Neighborhood Hits	981	Shared Neighborhood Hits	95
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

MAP1B_HUMAN
θ value	0.21417 (rank : 108)	NC score	0.135687 (rank : 132)
Query Neighborhood Hits	326	Target Neighborhood Hits	903	Shared Neighborhood Hits	103
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MPP8_HUMAN
θ value	0.21417 (rank : 109)	NC score	0.127616 (rank : 173)
Query Neighborhood Hits	326	Target Neighborhood Hits	948	Shared Neighborhood Hits	153
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

REN3B_HUMAN
θ value	0.21417 (rank : 110)	NC score	0.139585 (rank : 121)
Query Neighborhood Hits	326	Target Neighborhood Hits	412	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

TOP1_HUMAN
θ value	0.21417 (rank : 111)	NC score	0.085576 (rank : 535)
Query Neighborhood Hits	326	Target Neighborhood Hits	207	Shared Neighborhood Hits	49
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

BC11A_HUMAN
θ value	0.279714 (rank : 112)	NC score	0.007728 (rank : 1226)
Query Neighborhood Hits	326	Target Neighborhood Hits	745	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

BC11A_MOUSE
θ value	0.279714 (rank : 113)	NC score	0.011551 (rank : 1222)
Query Neighborhood Hits	326	Target Neighborhood Hits	732	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

CIR_HUMAN
θ value	0.279714 (rank : 114)	NC score	0.079079 (rank : 597)
Query Neighborhood Hits	326	Target Neighborhood Hits	249	Shared Neighborhood Hits	39
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

FGR_MOUSE
θ value	0.279714 (rank : 115)	NC score	0.149165 (rank : 99)
Query Neighborhood Hits	326	Target Neighborhood Hits	1069	Shared Neighborhood Hits	104
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FRK_HUMAN
θ value	0.279714 (rank : 116)	NC score	0.135172 (rank : 134)
Query Neighborhood Hits	326	Target Neighborhood Hits	1058	Shared Neighborhood Hits	98
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

INCE_MOUSE
θ value	0.279714 (rank : 117)	NC score	0.133573 (rank : 145)
Query Neighborhood Hits	326	Target Neighborhood Hits	903	Shared Neighborhood Hits	111
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

CALD1_HUMAN
θ value	0.365318 (rank : 118)	NC score	0.133250 (rank : 146)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	133
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

ITSN2_HUMAN
θ value	0.365318 (rank : 119)	NC score	0.119605 (rank : 226)
Query Neighborhood Hits	326	Target Neighborhood Hits	1173	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MFAP1_MOUSE
θ value	0.365318 (rank : 120)	NC score	0.110130 (rank : 308)
Query Neighborhood Hits	326	Target Neighborhood Hits	353	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

NFH_MOUSE
θ value	0.365318 (rank : 121)	NC score	0.070329 (rank : 732)
Query Neighborhood Hits	326	Target Neighborhood Hits	2247	Shared Neighborhood Hits	154
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RADI_HUMAN
θ value	0.365318 (rank : 122)	NC score	0.086644 (rank : 520)
Query Neighborhood Hits	326	Target Neighborhood Hits	741	Shared Neighborhood Hits	100
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RBBP6_MOUSE
θ value	0.365318 (rank : 123)	NC score	0.143592 (rank : 110)
Query Neighborhood Hits	326	Target Neighborhood Hits	1014	Shared Neighborhood Hits	113
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SH21B_MOUSE
θ value	0.365318 (rank : 124)	NC score	0.277092 (rank : 34)
Query Neighborhood Hits	326	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

ZFP37_MOUSE
θ value	0.365318 (rank : 125)	NC score	0.000832 (rank : 1230)
Query Neighborhood Hits	326	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

BRE1A_MOUSE
θ value	0.47712 (rank : 126)	NC score	0.121217 (rank : 216)
Query Neighborhood Hits	326	Target Neighborhood Hits	1025	Shared Neighborhood Hits	110
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CE290_HUMAN
θ value	0.47712 (rank : 127)	NC score	0.134857 (rank : 136)
Query Neighborhood Hits	326	Target Neighborhood Hits	1553	Shared Neighborhood Hits	161
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CP250_MOUSE
θ value	0.47712 (rank : 128)	NC score	0.116445 (rank : 257)
Query Neighborhood Hits	326	Target Neighborhood Hits	1583	Shared Neighborhood Hits	158
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CROP_MOUSE
θ value	0.47712 (rank : 129)	NC score	0.108387 (rank : 325)
Query Neighborhood Hits	326	Target Neighborhood Hits	403	Shared Neighborhood Hits	69
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

DYXC1_MOUSE
θ value	0.47712 (rank : 130)	NC score	0.062781 (rank : 898)
Query Neighborhood Hits	326	Target Neighborhood Hits	172	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

ITSN2_MOUSE
θ value	0.47712 (rank : 131)	NC score	0.134217 (rank : 141)
Query Neighborhood Hits	326	Target Neighborhood Hits	1371	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

NDE1_HUMAN
θ value	0.47712 (rank : 132)	NC score	0.118336 (rank : 241)
Query Neighborhood Hits	326	Target Neighborhood Hits	823	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

REST_MOUSE
θ value	0.47712 (rank : 133)	NC score	0.120597 (rank : 218)
Query Neighborhood Hits	326	Target Neighborhood Hits	1506	Shared Neighborhood Hits	161
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SLAP1_HUMAN
θ value	0.47712 (rank : 134)	NC score	0.243901 (rank : 48)
Query Neighborhood Hits	326	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

TAF3_HUMAN
θ value	0.47712 (rank : 135)	NC score	0.116492 (rank : 256)
Query Neighborhood Hits	326	Target Neighborhood Hits	568	Shared Neighborhood Hits	78
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CD2L1_HUMAN
θ value	0.62314 (rank : 136)	NC score	0.061534 (rank : 920)
Query Neighborhood Hits	326	Target Neighborhood Hits	1467	Shared Neighborhood Hits	119
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CRKL_HUMAN
θ value	0.62314 (rank : 137)	NC score	0.255655 (rank : 43)
Query Neighborhood Hits	326	Target Neighborhood Hits	313	Shared Neighborhood Hits	92
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

DDX21_HUMAN
θ value	0.62314 (rank : 138)	NC score	0.026601 (rank : 1206)
Query Neighborhood Hits	326	Target Neighborhood Hits	308	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

MYH9_HUMAN
θ value	0.62314 (rank : 139)	NC score	0.109498 (rank : 315)
Query Neighborhood Hits	326	Target Neighborhood Hits	1762	Shared Neighborhood Hits	172
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYST4_HUMAN
θ value	0.62314 (rank : 140)	NC score	0.060831 (rank : 938)
Query Neighborhood Hits	326	Target Neighborhood Hits	671	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NFH_HUMAN
θ value	0.62314 (rank : 141)	NC score	0.079090 (rank : 596)
Query Neighborhood Hits	326	Target Neighborhood Hits	1242	Shared Neighborhood Hits	134
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PLCG2_HUMAN
θ value	0.62314 (rank : 142)	NC score	0.287690 (rank : 32)
Query Neighborhood Hits	326	Target Neighborhood Hits	280	Shared Neighborhood Hits	88
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

SELS_HUMAN
θ value	0.62314 (rank : 143)	NC score	0.065322 (rank : 850)
Query Neighborhood Hits	326	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQE4, Q3B771, Q9P0I6	Gene names	SELS, VIMP
Domain Architecture
Description	Selenoprotein S (VCP-interacting membrane protein).

SHC2_MOUSE
θ value	0.62314 (rank : 144)	NC score	0.252206 (rank : 46)
Query Neighborhood Hits	326	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SYCP1_MOUSE
θ value	0.62314 (rank : 145)	NC score	0.142256 (rank : 112)
Query Neighborhood Hits	326	Target Neighborhood Hits	1456	Shared Neighborhood Hits	172
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TMF1_HUMAN
θ value	0.62314 (rank : 146)	NC score	0.118662 (rank : 236)
Query Neighborhood Hits	326	Target Neighborhood Hits	987	Shared Neighborhood Hits	121
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

U2AFL_MOUSE
θ value	0.62314 (rank : 147)	NC score	0.087897 (rank : 505)
Query Neighborhood Hits	326	Target Neighborhood Hits	389	Shared Neighborhood Hits	63
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

UBP8_HUMAN
θ value	0.62314 (rank : 148)	NC score	0.073589 (rank : 668)
Query Neighborhood Hits	326	Target Neighborhood Hits	751	Shared Neighborhood Hits	129
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

VAV2_HUMAN
θ value	0.62314 (rank : 149)	NC score	0.179652 (rank : 66)
Query Neighborhood Hits	326	Target Neighborhood Hits	453	Shared Neighborhood Hits	88
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ZRF1_HUMAN
θ value	0.62314 (rank : 150)	NC score	0.092435 (rank : 455)
Query Neighborhood Hits	326	Target Neighborhood Hits	457	Shared Neighborhood Hits	63
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

BRDT_MOUSE
θ value	0.813845 (rank : 151)	NC score	0.039124 (rank : 1180)
Query Neighborhood Hits	326	Target Neighborhood Hits	243	Shared Neighborhood Hits	46
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

MFAP1_HUMAN
θ value	0.813845 (rank : 152)	NC score	0.112736 (rank : 285)
Query Neighborhood Hits	326	Target Neighborhood Hits	321	Shared Neighborhood Hits	64
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MYH11_HUMAN
θ value	0.813845 (rank : 153)	NC score	0.112390 (rank : 288)
Query Neighborhood Hits	326	Target Neighborhood Hits	1806	Shared Neighborhood Hits	182
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	0.813845 (rank : 154)	NC score	0.111961 (rank : 293)
Query Neighborhood Hits	326	Target Neighborhood Hits	1777	Shared Neighborhood Hits	179
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYST3_HUMAN
θ value	0.813845 (rank : 155)	NC score	0.064403 (rank : 866)
Query Neighborhood Hits	326	Target Neighborhood Hits	772	Shared Neighborhood Hits	80
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PEPL_MOUSE
θ value	0.813845 (rank : 156)	NC score	0.128496 (rank : 165)
Query Neighborhood Hits	326	Target Neighborhood Hits	1105	Shared Neighborhood Hits	141
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PRP4B_HUMAN
θ value	0.813845 (rank : 157)	NC score	0.052335 (rank : 1106)
Query Neighborhood Hits	326	Target Neighborhood Hits	1030	Shared Neighborhood Hits	86
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RADI_MOUSE
θ value	0.813845 (rank : 158)	NC score	0.081248 (rank : 574)
Query Neighborhood Hits	326	Target Neighborhood Hits	773	Shared Neighborhood Hits	97
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

SCG1_MOUSE
θ value	0.813845 (rank : 159)	NC score	0.063795 (rank : 879)
Query Neighborhood Hits	326	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

SLAP1_MOUSE
θ value	0.813845 (rank : 160)	NC score	0.242686 (rank : 49)
Query Neighborhood Hits	326	Target Neighborhood Hits	117	Shared Neighborhood Hits	75
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

TTC16_HUMAN
θ value	0.813845 (rank : 161)	NC score	0.067322 (rank : 797)
Query Neighborhood Hits	326	Target Neighborhood Hits	417	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

BAZ2A_HUMAN
θ value	1.06291 (rank : 162)	NC score	0.053783 (rank : 1075)
Query Neighborhood Hits	326	Target Neighborhood Hits	780	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

HCK_HUMAN
θ value	1.06291 (rank : 163)	NC score	0.130167 (rank : 158)
Query Neighborhood Hits	326	Target Neighborhood Hits	1035	Shared Neighborhood Hits	100
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

INCE_HUMAN
θ value	1.06291 (rank : 164)	NC score	0.129647 (rank : 160)
Query Neighborhood Hits	326	Target Neighborhood Hits	978	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

MACOI_MOUSE
θ value	1.06291 (rank : 165)	NC score	0.113826 (rank : 270)
Query Neighborhood Hits	326	Target Neighborhood Hits	620	Shared Neighborhood Hits	93
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MAP1B_MOUSE
θ value	1.06291 (rank : 166)	NC score	0.125750 (rank : 184)
Query Neighborhood Hits	326	Target Neighborhood Hits	977	Shared Neighborhood Hits	97
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

SEP11_MOUSE
θ value	1.06291 (rank : 167)	NC score	0.037941 (rank : 1181)
Query Neighborhood Hits	326	Target Neighborhood Hits	300	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

SMC1A_HUMAN
θ value	1.06291 (rank : 168)	NC score	0.148886 (rank : 101)
Query Neighborhood Hits	326	Target Neighborhood Hits	1346	Shared Neighborhood Hits	169
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	1.06291 (rank : 169)	NC score	0.154412 (rank : 88)
Query Neighborhood Hits	326	Target Neighborhood Hits	1384	Shared Neighborhood Hits	174
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SOCS6_HUMAN
θ value	1.06291 (rank : 170)	NC score	0.173923 (rank : 71)
Query Neighborhood Hits	326	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	O14544	Gene names	SOCS6, CIS4, SOCS4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

SOCS6_MOUSE
θ value	1.06291 (rank : 171)	NC score	0.178664 (rank : 68)
Query Neighborhood Hits	326	Target Neighborhood Hits	146	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

SRC_HUMAN
θ value	1.06291 (rank : 172)	NC score	0.134352 (rank : 140)
Query Neighborhood Hits	326	Target Neighborhood Hits	1058	Shared Neighborhood Hits	99
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRC_MOUSE
θ value	1.06291 (rank : 173)	NC score	0.134396 (rank : 139)
Query Neighborhood Hits	326	Target Neighborhood Hits	1033	Shared Neighborhood Hits	99
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

TOP1_MOUSE
θ value	1.06291 (rank : 174)	NC score	0.095041 (rank : 428)
Query Neighborhood Hits	326	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

ZRF1_MOUSE
θ value	1.06291 (rank : 175)	NC score	0.096734 (rank : 412)
Query Neighborhood Hits	326	Target Neighborhood Hits	414	Shared Neighborhood Hits	62
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

ACINU_HUMAN
θ value	1.38821 (rank : 176)	NC score	0.152632 (rank : 92)
Query Neighborhood Hits	326	Target Neighborhood Hits	828	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	1.38821 (rank : 177)	NC score	0.115746 (rank : 262)
Query Neighborhood Hits	326	Target Neighborhood Hits	712	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CHD2_HUMAN
θ value	1.38821 (rank : 178)	NC score	0.032482 (rank : 1192)
Query Neighborhood Hits	326	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CROP_HUMAN
θ value	1.38821 (rank : 179)	NC score	0.103150 (rank : 368)
Query Neighborhood Hits	326	Target Neighborhood Hits	402	Shared Neighborhood Hits	69
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CT116_MOUSE
θ value	1.38821 (rank : 180)	NC score	0.084417 (rank : 542)
Query Neighborhood Hits	326	Target Neighborhood Hits	268	Shared Neighborhood Hits	52
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

EVPL_MOUSE
θ value	1.38821 (rank : 181)	NC score	0.108481 (rank : 323)
Query Neighborhood Hits	326	Target Neighborhood Hits	952	Shared Neighborhood Hits	123
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

JHD2C_MOUSE
θ value	1.38821 (rank : 182)	NC score	0.029326 (rank : 1200)
Query Neighborhood Hits	326	Target Neighborhood Hits	297	Shared Neighborhood Hits	40
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

MOES_MOUSE
θ value	1.38821 (rank : 183)	NC score	0.083809 (rank : 546)
Query Neighborhood Hits	326	Target Neighborhood Hits	923	Shared Neighborhood Hits	112
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYH9_MOUSE
θ value	1.38821 (rank : 184)	NC score	0.112326 (rank : 289)
Query Neighborhood Hits	326	Target Neighborhood Hits	1829	Shared Neighborhood Hits	182
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PRGC2_HUMAN
θ value	1.38821 (rank : 185)	NC score	0.037639 (rank : 1182)
Query Neighborhood Hits	326	Target Neighborhood Hits	272	Shared Neighborhood Hits	14
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

PRP40_HUMAN
θ value	1.38821 (rank : 186)	NC score	0.117433 (rank : 249)
Query Neighborhood Hits	326	Target Neighborhood Hits	442	Shared Neighborhood Hits	92
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

RHG12_HUMAN
θ value	1.38821 (rank : 187)	NC score	0.032713 (rank : 1191)
Query Neighborhood Hits	326	Target Neighborhood Hits	190	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RU17_HUMAN
θ value	1.38821 (rank : 188)	NC score	0.049329 (rank : 1168)
Query Neighborhood Hits	326	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

SH21B_HUMAN
θ value	1.38821 (rank : 189)	NC score	0.264872 (rank : 40)
Query Neighborhood Hits	326	Target Neighborhood Hits	101	Shared Neighborhood Hits	61
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

VAV2_MOUSE
θ value	1.38821 (rank : 190)	NC score	0.173896 (rank : 72)
Query Neighborhood Hits	326	Target Neighborhood Hits	456	Shared Neighborhood Hits	85
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ANR11_HUMAN
θ value	1.81305 (rank : 191)	NC score	0.073278 (rank : 672)
Query Neighborhood Hits	326	Target Neighborhood Hits	1289	Shared Neighborhood Hits	129
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR12_HUMAN
θ value	1.81305 (rank : 192)	NC score	0.089393 (rank : 491)
Query Neighborhood Hits	326	Target Neighborhood Hits	1081	Shared Neighborhood Hits	150
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CCD19_HUMAN
θ value	1.81305 (rank : 193)	NC score	0.124936 (rank : 191)
Query Neighborhood Hits	326	Target Neighborhood Hits	639	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CD2L1_MOUSE
θ value	1.81305 (rank : 194)	NC score	0.059846 (rank : 952)
Query Neighborhood Hits	326	Target Neighborhood Hits	1463	Shared Neighborhood Hits	115
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CING_HUMAN
θ value	1.81305 (rank : 195)	NC score	0.118383 (rank : 240)
Query Neighborhood Hits	326	Target Neighborhood Hits	1275	Shared Neighborhood Hits	153
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CTR9_MOUSE
θ value	1.81305 (rank : 196)	NC score	0.053764 (rank : 1076)
Query Neighborhood Hits	326	Target Neighborhood Hits	427	Shared Neighborhood Hits	54
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

DYXC1_HUMAN
θ value	1.81305 (rank : 197)	NC score	0.083392 (rank : 550)
Query Neighborhood Hits	326	Target Neighborhood Hits	261	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

FGR_HUMAN
θ value	1.81305 (rank : 198)	NC score	0.140319 (rank : 119)
Query Neighborhood Hits	326	Target Neighborhood Hits	1067	Shared Neighborhood Hits	100
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ING2_HUMAN
θ value	1.81305 (rank : 199)	NC score	0.052702 (rank : 1099)
Query Neighborhood Hits	326	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

MYT1_HUMAN
θ value	1.81305 (rank : 200)	NC score	0.043134 (rank : 1176)
Query Neighborhood Hits	326	Target Neighborhood Hits	475	Shared Neighborhood Hits	64
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NOG1_HUMAN
θ value	1.81305 (rank : 201)	NC score	0.033421 (rank : 1189)
Query Neighborhood Hits	326	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

NOP14_MOUSE
θ value	1.81305 (rank : 202)	NC score	0.089584 (rank : 487)
Query Neighborhood Hits	326	Target Neighborhood Hits	324	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PRP16_HUMAN
θ value	1.81305 (rank : 203)	NC score	0.018715 (rank : 1213)
Query Neighborhood Hits	326	Target Neighborhood Hits	135	Shared Neighborhood Hits	18
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

RRBP1_MOUSE
θ value	1.81305 (rank : 204)	NC score	0.138174 (rank : 128)
Query Neighborhood Hits	326	Target Neighborhood Hits	1650	Shared Neighborhood Hits	177
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RU17_MOUSE
θ value	1.81305 (rank : 205)	NC score	0.047573 (rank : 1170)
Query Neighborhood Hits	326	Target Neighborhood Hits	278	Shared Neighborhood Hits	25
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

SH23A_HUMAN
θ value	1.81305 (rank : 206)	NC score	0.216365 (rank : 56)
Query Neighborhood Hits	326	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

SRR35_HUMAN
θ value	1.81305 (rank : 207)	NC score	0.031634 (rank : 1194)
Query Neighborhood Hits	326	Target Neighborhood Hits	215	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXF0, Q8WW25	Gene names	SRRP35
Domain Architecture
Description	35 kDa SR repressor protein (SRrp35).

TARA_HUMAN
θ value	1.81305 (rank : 208)	NC score	0.092422 (rank : 456)
Query Neighborhood Hits	326	Target Neighborhood Hits	1626	Shared Neighborhood Hits	142
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CHIO_HUMAN
θ value	2.36792 (rank : 209)	NC score	0.103956 (rank : 360)
Query Neighborhood Hits	326	Target Neighborhood Hits	220	Shared Neighborhood Hits	73
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CK5P2_HUMAN
θ value	2.36792 (rank : 210)	NC score	0.142079 (rank : 114)
Query Neighborhood Hits	326	Target Neighborhood Hits	1433	Shared Neighborhood Hits	180
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CLOCK_MOUSE
θ value	2.36792 (rank : 211)	NC score	0.024368 (rank : 1208)
Query Neighborhood Hits	326	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

LRC59_MOUSE
θ value	2.36792 (rank : 212)	NC score	0.017300 (rank : 1215)
Query Neighborhood Hits	326	Target Neighborhood Hits	415	Shared Neighborhood Hits	26
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

NO40_HUMAN
θ value	2.36792 (rank : 213)	NC score	0.030388 (rank : 1196)
Query Neighborhood Hits	326	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP64, Q6PKH4, Q9NYG4, Q9P0M8	Gene names	ZCCHC17, PS1D
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein) (Pnn-interacting nucleolar protein).

RABE1_MOUSE
θ value	2.36792 (rank : 214)	NC score	0.118882 (rank : 232)
Query Neighborhood Hits	326	Target Neighborhood Hits	1105	Shared Neighborhood Hits	139
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RBMX2_MOUSE
θ value	2.36792 (rank : 215)	NC score	0.057398 (rank : 988)
Query Neighborhood Hits	326	Target Neighborhood Hits	287	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

RIMB1_HUMAN
θ value	2.36792 (rank : 216)	NC score	0.125346 (rank : 190)
Query Neighborhood Hits	326	Target Neighborhood Hits	1479	Shared Neighborhood Hits	163
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SELS_MOUSE
θ value	2.36792 (rank : 217)	NC score	0.057297 (rank : 993)
Query Neighborhood Hits	326	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BCZ4, Q921S1, Q9DB55	Gene names	Sels, H47, Vimp
Domain Architecture
Description	Selenoprotein S (VCP-interacting membrane protein) (Minor histocompatibility antigen H47).

SEP11_HUMAN
θ value	2.36792 (rank : 218)	NC score	0.034406 (rank : 1186)
Query Neighborhood Hits	326	Target Neighborhood Hits	296	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

SHC2_HUMAN
θ value	2.36792 (rank : 219)	NC score	0.250559 (rank : 47)
Query Neighborhood Hits	326	Target Neighborhood Hits	170	Shared Neighborhood Hits	81
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

TRIPB_HUMAN
θ value	2.36792 (rank : 220)	NC score	0.127210 (rank : 180)
Query Neighborhood Hits	326	Target Neighborhood Hits	1587	Shared Neighborhood Hits	158
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

U2AFM_MOUSE
θ value	2.36792 (rank : 221)	NC score	0.086999 (rank : 517)
Query Neighborhood Hits	326	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

VAV3_HUMAN
θ value	2.36792 (rank : 222)	NC score	0.180681 (rank : 64)
Query Neighborhood Hits	326	Target Neighborhood Hits	398	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

WDR60_HUMAN
θ value	2.36792 (rank : 223)	NC score	0.074006 (rank : 661)
Query Neighborhood Hits	326	Target Neighborhood Hits	286	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

BRD2_HUMAN
θ value	3.0926 (rank : 224)	NC score	0.028906 (rank : 1201)
Query Neighborhood Hits	326	Target Neighborhood Hits	242	Shared Neighborhood Hits	25
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

CLOCK_HUMAN
θ value	3.0926 (rank : 225)	NC score	0.023413 (rank : 1209)
Query Neighborhood Hits	326	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

EDC3_MOUSE
θ value	3.0926 (rank : 226)	NC score	0.028808 (rank : 1202)
Query Neighborhood Hits	326	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2D3, Q3THV7	Gene names	Edc3, Yjdc
Domain Architecture	No domain graphic available
Description	Enhancer of mRNA decapping protein 3 (YjeF domain-containing protein 1).

EEA1_MOUSE
θ value	3.0926 (rank : 227)	NC score	0.121366 (rank : 215)
Query Neighborhood Hits	326	Target Neighborhood Hits	1637	Shared Neighborhood Hits	166
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EST1A_MOUSE
θ value	3.0926 (rank : 228)	NC score	0.034328 (rank : 1187)
Query Neighborhood Hits	326	Target Neighborhood Hits	138	Shared Neighborhood Hits	30
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

GOGA6_HUMAN
θ value	3.0926 (rank : 229)	NC score	0.118844 (rank : 235)
Query Neighborhood Hits	326	Target Neighborhood Hits	1007	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

IGBP1_HUMAN
θ value	3.0926 (rank : 230)	NC score	0.041009 (rank : 1179)
Query Neighborhood Hits	326	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	P78318, Q8TAB2	Gene names	IGBP1
Domain Architecture
Description	Immunoglobulin-binding protein 1 (CD79a-binding protein 1) (B cell signal transduction molecule alpha 4) (Alpha 4 protein) (NY-REN-16 antigen).

NDE1_MOUSE
θ value	3.0926 (rank : 231)	NC score	0.099595 (rank : 394)
Query Neighborhood Hits	326	Target Neighborhood Hits	602	Shared Neighborhood Hits	93
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

NEK11_MOUSE
θ value	3.0926 (rank : 232)	NC score	0.048117 (rank : 1169)
Query Neighborhood Hits	326	Target Neighborhood Hits	875	Shared Neighborhood Hits	46
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

NIPBL_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.141736 (rank : 115)
Query Neighborhood Hits	326	Target Neighborhood Hits	1311	Shared Neighborhood Hits	150
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPHP3_HUMAN
θ value	3.0926 (rank : 234)	NC score	0.050541 (rank : 1154)
Query Neighborhood Hits	326	Target Neighborhood Hits	304	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

PPIG_HUMAN
θ value	3.0926 (rank : 235)	NC score	0.094708 (rank : 435)
Query Neighborhood Hits	326	Target Neighborhood Hits	670	Shared Neighborhood Hits	125
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RABE1_HUMAN
θ value	3.0926 (rank : 236)	NC score	0.114907 (rank : 265)
Query Neighborhood Hits	326	Target Neighborhood Hits	1104	Shared Neighborhood Hits	128
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RPGR1_MOUSE
θ value	3.0926 (rank : 237)	NC score	0.094038 (rank : 442)
Query Neighborhood Hits	326	Target Neighborhood Hits	713	Shared Neighborhood Hits	91
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CAC1H_HUMAN
θ value	4.03905 (rank : 238)	NC score	0.010584 (rank : 1224)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CENPF_HUMAN
θ value	4.03905 (rank : 239)	NC score	0.125498 (rank : 188)
Query Neighborhood Hits	326	Target Neighborhood Hits	1932	Shared Neighborhood Hits	182
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CNTRB_HUMAN
θ value	4.03905 (rank : 240)	NC score	0.098685 (rank : 396)
Query Neighborhood Hits	326	Target Neighborhood Hits	690	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP250_HUMAN
θ value	4.03905 (rank : 241)	NC score	0.131678 (rank : 153)
Query Neighborhood Hits	326	Target Neighborhood Hits	1805	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DAXX_HUMAN
θ value	4.03905 (rank : 242)	NC score	0.047351 (rank : 1171)
Query Neighborhood Hits	326	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DIDO1_HUMAN
θ value	4.03905 (rank : 243)	NC score	0.034956 (rank : 1184)
Query Neighborhood Hits	326	Target Neighborhood Hits	960	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EHMT2_HUMAN
θ value	4.03905 (rank : 244)	NC score	0.011568 (rank : 1221)
Query Neighborhood Hits	326	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EXOC5_HUMAN
θ value	4.03905 (rank : 245)	NC score	0.047287 (rank : 1172)
Query Neighborhood Hits	326	Target Neighborhood Hits	194	Shared Neighborhood Hits	44
SwissProt Accessions	O00471	Gene names	EXOC5, SEC10, SEC10L1
Domain Architecture
Description	Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10).

ING2_MOUSE
θ value	4.03905 (rank : 246)	NC score	0.041661 (rank : 1178)
Query Neighborhood Hits	326	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

ITK_MOUSE
θ value	4.03905 (rank : 247)	NC score	0.114490 (rank : 268)
Query Neighborhood Hits	326	Target Neighborhood Hits	985	Shared Neighborhood Hits	93
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

KI21A_HUMAN
θ value	4.03905 (rank : 248)	NC score	0.089114 (rank : 494)
Query Neighborhood Hits	326	Target Neighborhood Hits	1543	Shared Neighborhood Hits	163
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KIF5A_MOUSE
θ value	4.03905 (rank : 249)	NC score	0.068962 (rank : 760)
Query Neighborhood Hits	326	Target Neighborhood Hits	859	Shared Neighborhood Hits	107
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KINH_HUMAN
θ value	4.03905 (rank : 250)	NC score	0.102657 (rank : 373)
Query Neighborhood Hits	326	Target Neighborhood Hits	1231	Shared Neighborhood Hits	158
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

LYN_HUMAN
θ value	4.03905 (rank : 251)	NC score	0.121572 (rank : 214)
Query Neighborhood Hits	326	Target Neighborhood Hits	1022	Shared Neighborhood Hits	97
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MATK_HUMAN
θ value	4.03905 (rank : 252)	NC score	0.126688 (rank : 183)
Query Neighborhood Hits	326	Target Neighborhood Hits	954	Shared Neighborhood Hits	99
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MYH13_HUMAN
θ value	4.03905 (rank : 253)	NC score	0.099927 (rank : 391)
Query Neighborhood Hits	326	Target Neighborhood Hits	1504	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYO6_HUMAN
θ value	4.03905 (rank : 254)	NC score	0.076128 (rank : 638)
Query Neighborhood Hits	326	Target Neighborhood Hits	727	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

NAF1_HUMAN
θ value	4.03905 (rank : 255)	NC score	0.115422 (rank : 264)
Query Neighborhood Hits	326	Target Neighborhood Hits	937	Shared Neighborhood Hits	132
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NFM_MOUSE
θ value	4.03905 (rank : 256)	NC score	0.076897 (rank : 629)
Query Neighborhood Hits	326	Target Neighborhood Hits	1159	Shared Neighborhood Hits	135
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PRP4B_MOUSE
θ value	4.03905 (rank : 257)	NC score	0.052215 (rank : 1108)
Query Neighborhood Hits	326	Target Neighborhood Hits	1040	Shared Neighborhood Hits	87
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

SON_MOUSE
θ value	4.03905 (rank : 258)	NC score	0.045408 (rank : 1173)
Query Neighborhood Hits	326	Target Neighborhood Hits	957	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TENS1_HUMAN
θ value	4.03905 (rank : 259)	NC score	0.096381 (rank : 415)
Query Neighborhood Hits	326	Target Neighborhood Hits	400	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

UBF1_HUMAN
θ value	4.03905 (rank : 260)	NC score	0.069378 (rank : 749)
Query Neighborhood Hits	326	Target Neighborhood Hits	415	Shared Neighborhood Hits	63
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

AKAP9_HUMAN
θ value	5.27518 (rank : 261)	NC score	0.117713 (rank : 244)
Query Neighborhood Hits	326	Target Neighborhood Hits	1710	Shared Neighborhood Hits	159
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CN145_MOUSE
θ value	5.27518 (rank : 262)	NC score	0.106211 (rank : 341)
Query Neighborhood Hits	326	Target Neighborhood Hits	916	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CRK_HUMAN
θ value	5.27518 (rank : 263)	NC score	0.238301 (rank : 50)
Query Neighborhood Hits	326	Target Neighborhood Hits	308	Shared Neighborhood Hits	91
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	5.27518 (rank : 264)	NC score	0.236695 (rank : 51)
Query Neighborhood Hits	326	Target Neighborhood Hits	314	Shared Neighborhood Hits	91
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

DHX16_HUMAN
θ value	5.27518 (rank : 265)	NC score	0.062170 (rank : 912)
Query Neighborhood Hits	326	Target Neighborhood Hits	356	Shared Neighborhood Hits	74
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

EHMT2_MOUSE
θ value	5.27518 (rank : 266)	NC score	0.015512 (rank : 1219)
Query Neighborhood Hits	326	Target Neighborhood Hits	750	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EXOSX_MOUSE
θ value	5.27518 (rank : 267)	NC score	0.016876 (rank : 1216)
Query Neighborhood Hits	326	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P56960, Q9QYS8, Q9R0B1	Gene names	Exosc10, Pmscl2
Domain Architecture
Description	Exosome component 10 (Polymyositis/scleroderma autoantigen 2 homolog) (Autoantigen PM/Scl 2 homolog).

HIRP3_HUMAN
θ value	5.27518 (rank : 268)	NC score	0.095063 (rank : 427)
Query Neighborhood Hits	326	Target Neighborhood Hits	323	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

JAD1A_HUMAN
θ value	5.27518 (rank : 269)	NC score	0.029409 (rank : 1199)
Query Neighborhood Hits	326	Target Neighborhood Hits	328	Shared Neighborhood Hits	50
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

MATK_MOUSE
θ value	5.27518 (rank : 270)	NC score	0.125739 (rank : 186)
Query Neighborhood Hits	326	Target Neighborhood Hits	952	Shared Neighborhood Hits	99
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MYPT1_HUMAN
θ value	5.27518 (rank : 271)	NC score	0.035647 (rank : 1183)
Query Neighborhood Hits	326	Target Neighborhood Hits	723	Shared Neighborhood Hits	89
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

NPHP3_MOUSE
θ value	5.27518 (rank : 272)	NC score	0.051409 (rank : 1131)
Query Neighborhood Hits	326	Target Neighborhood Hits	335	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

PEPL_HUMAN
θ value	5.27518 (rank : 273)	NC score	0.116600 (rank : 255)
Query Neighborhood Hits	326	Target Neighborhood Hits	1141	Shared Neighborhood Hits	141
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PHF14_HUMAN
θ value	5.27518 (rank : 274)	NC score	0.045391 (rank : 1174)
Query Neighborhood Hits	326	Target Neighborhood Hits	447	Shared Neighborhood Hits	67
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PRGC2_MOUSE
θ value	5.27518 (rank : 275)	NC score	0.030351 (rank : 1197)
Query Neighborhood Hits	326	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PRP40_MOUSE
θ value	5.27518 (rank : 276)	NC score	0.117308 (rank : 250)
Query Neighborhood Hits	326	Target Neighborhood Hits	447	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RBP1_HUMAN
θ value	5.27518 (rank : 277)	NC score	0.051700 (rank : 1123)
Query Neighborhood Hits	326	Target Neighborhood Hits	521	Shared Neighborhood Hits	68
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RCOR2_HUMAN
θ value	5.27518 (rank : 278)	NC score	0.016660 (rank : 1217)
Query Neighborhood Hits	326	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

SEC62_HUMAN
θ value	5.27518 (rank : 279)	NC score	0.042920 (rank : 1177)
Query Neighborhood Hits	326	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

SNPC1_HUMAN
θ value	5.27518 (rank : 280)	NC score	0.021267 (rank : 1212)
Query Neighborhood Hits	326	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q16533	Gene names	SNAPC1, SNAP43
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (snRNA- activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) (Small nuclear RNA-activating complex polypeptide 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE- binding factor subunit gamma) (PTF subunit gamma).

TAOK1_HUMAN
θ value	5.27518 (rank : 281)	NC score	0.088048 (rank : 504)
Query Neighborhood Hits	326	Target Neighborhood Hits	1734	Shared Neighborhood Hits	188
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

VAV3_MOUSE
θ value	5.27518 (rank : 282)	NC score	0.180565 (rank : 65)
Query Neighborhood Hits	326	Target Neighborhood Hits	404	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ANGL3_MOUSE
θ value	6.88961 (rank : 283)	NC score	0.031318 (rank : 1195)
Query Neighborhood Hits	326	Target Neighborhood Hits	306	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ARS2_MOUSE
θ value	6.88961 (rank : 284)	NC score	0.034663 (rank : 1185)
Query Neighborhood Hits	326	Target Neighborhood Hits	212	Shared Neighborhood Hits	26
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

BICD1_MOUSE
θ value	6.88961 (rank : 285)	NC score	0.108936 (rank : 322)
Query Neighborhood Hits	326	Target Neighborhood Hits	837	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BLK_MOUSE
θ value	6.88961 (rank : 286)	NC score	0.128129 (rank : 166)
Query Neighborhood Hits	326	Target Neighborhood Hits	992	Shared Neighborhood Hits	99
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

CCD25_MOUSE
θ value	6.88961 (rank : 287)	NC score	0.032162 (rank : 1193)
Query Neighborhood Hits	326	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q78PG9, Q9CSQ8, Q9CUF8	Gene names	Ccdc25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

CCD96_MOUSE
θ value	6.88961 (rank : 288)	NC score	0.138979 (rank : 124)
Query Neighborhood Hits	326	Target Neighborhood Hits	704	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CIZ1_HUMAN
θ value	6.88961 (rank : 289)	NC score	0.022653 (rank : 1211)
Query Neighborhood Hits	326	Target Neighborhood Hits	359	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

DIAP1_HUMAN
θ value	6.88961 (rank : 290)	NC score	0.049853 (rank : 1167)
Query Neighborhood Hits	326	Target Neighborhood Hits	784	Shared Neighborhood Hits	81
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
θ value	6.88961 (rank : 291)	NC score	0.062655 (rank : 903)
Query Neighborhood Hits	326	Target Neighborhood Hits	839	Shared Neighborhood Hits	97
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

GOGA3_HUMAN
θ value	6.88961 (rank : 292)	NC score	0.105118 (rank : 350)
Query Neighborhood Hits	326	Target Neighborhood Hits	1317	Shared Neighborhood Hits	133
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

LMNB2_HUMAN
θ value	6.88961 (rank : 293)	NC score	0.069600 (rank : 746)
Query Neighborhood Hits	326	Target Neighborhood Hits	723	Shared Neighborhood Hits	100
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

LYN_MOUSE
θ value	6.88961 (rank : 294)	NC score	0.122050 (rank : 212)
Query Neighborhood Hits	326	Target Neighborhood Hits	1023	Shared Neighborhood Hits	98
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

PCLO_HUMAN
θ value	6.88961 (rank : 295)	NC score	0.056856 (rank : 1010)
Query Neighborhood Hits	326	Target Neighborhood Hits	2046	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCNT_HUMAN
θ value	6.88961 (rank : 296)	NC score	0.118903 (rank : 231)
Query Neighborhood Hits	326	Target Neighborhood Hits	1551	Shared Neighborhood Hits	159
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PF21B_HUMAN
θ value	6.88961 (rank : 297)	NC score	0.025623 (rank : 1207)
Query Neighborhood Hits	326	Target Neighborhood Hits	197	Shared Neighborhood Hits	25
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PJA1_MOUSE
θ value	6.88961 (rank : 298)	NC score	0.010056 (rank : 1225)
Query Neighborhood Hits	326	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RBM25_HUMAN
θ value	6.88961 (rank : 299)	NC score	0.115911 (rank : 261)
Query Neighborhood Hits	326	Target Neighborhood Hits	682	Shared Neighborhood Hits	93
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RL4_HUMAN
θ value	6.88961 (rank : 300)	NC score	0.018486 (rank : 1214)
Query Neighborhood Hits	326	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P36578, P39029, Q4VBR0, Q969Z9	Gene names	RPL4, RPL1
Domain Architecture
Description	60S ribosomal protein L4 (L1).

RUFY1_MOUSE
θ value	6.88961 (rank : 301)	NC score	0.071876 (rank : 703)
Query Neighborhood Hits	326	Target Neighborhood Hits	765	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

SCN2A_HUMAN
θ value	6.88961 (rank : 302)	NC score	0.005958 (rank : 1227)
Query Neighborhood Hits	326	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

TEX15_HUMAN
θ value	6.88961 (rank : 303)	NC score	0.033419 (rank : 1190)
Query Neighborhood Hits	326	Target Neighborhood Hits	174	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

ZC313_HUMAN
θ value	6.88961 (rank : 304)	NC score	0.128122 (rank : 167)
Query Neighborhood Hits	326	Target Neighborhood Hits	772	Shared Neighborhood Hits	131
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ADA30_HUMAN
θ value	8.99809 (rank : 305)	NC score	0.016523 (rank : 1218)
Query Neighborhood Hits	326	Target Neighborhood Hits	391	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ARMX5_MOUSE
θ value	8.99809 (rank : 306)	NC score	0.011483 (rank : 1223)
Query Neighborhood Hits	326	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

BICD1_HUMAN
θ value	8.99809 (rank : 307)	NC score	0.105043 (rank : 351)
Query Neighborhood Hits	326	Target Neighborhood Hits	844	Shared Neighborhood Hits	115
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CCAR1_MOUSE
θ value	8.99809 (rank : 308)	NC score	0.062628 (rank : 904)
Query Neighborhood Hits	326	Target Neighborhood Hits	414	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CCD25_HUMAN
θ value	8.99809 (rank : 309)	NC score	0.027699 (rank : 1204)
Query Neighborhood Hits	326	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q86WR0, Q96SI2, Q9NV98	Gene names	CCDC25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

CENPE_HUMAN
θ value	8.99809 (rank : 310)	NC score	0.122375 (rank : 210)
Query Neighborhood Hits	326	Target Neighborhood Hits	2060	Shared Neighborhood Hits	186
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CJ118_HUMAN
θ value	8.99809 (rank : 311)	NC score	0.091064 (rank : 470)
Query Neighborhood Hits	326	Target Neighborhood Hits	937	Shared Neighborhood Hits	99
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

DACH2_HUMAN
θ value	8.99809 (rank : 312)	NC score	0.027728 (rank : 1203)
Query Neighborhood Hits	326	Target Neighborhood Hits	122	Shared Neighborhood Hits	24
SwissProt Accessions	Q96NX9, Q8NAY3, Q8ND17, Q96N55	Gene names	DACH2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

DACH2_MOUSE
θ value	8.99809 (rank : 313)	NC score	0.027499 (rank : 1205)
Query Neighborhood Hits	326	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	Q925Q8, Q8BMA0	Gene names	Dach2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

DAXX_MOUSE
θ value	8.99809 (rank : 314)	NC score	0.033750 (rank : 1188)
Query Neighborhood Hits	326	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DDX27_HUMAN
θ value	8.99809 (rank : 315)	NC score	0.013147 (rank : 1220)
Query Neighborhood Hits	326	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

EDC3_HUMAN
θ value	8.99809 (rank : 316)	NC score	0.023394 (rank : 1210)
Query Neighborhood Hits	326	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96F86, Q9H797	Gene names	EDC3, YJDC
Domain Architecture	No domain graphic available
Description	Enhancer of mRNA decapping protein 3 (YjeF domain-containing protein 1).

GOGA1_MOUSE
θ value	8.99809 (rank : 317)	NC score	0.108323 (rank : 326)
Query Neighborhood Hits	326	Target Neighborhood Hits	994	Shared Neighborhood Hits	118
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

KIF5A_HUMAN
θ value	8.99809 (rank : 318)	NC score	0.068131 (rank : 782)
Query Neighborhood Hits	326	Target Neighborhood Hits	843	Shared Neighborhood Hits	107
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

LEO1_MOUSE
θ value	8.99809 (rank : 319)	NC score	0.109398 (rank : 318)
Query Neighborhood Hits	326	Target Neighborhood Hits	946	Shared Neighborhood Hits	113
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LOX12_MOUSE
θ value	8.99809 (rank : 320)	NC score	0.004190 (rank : 1228)
Query Neighborhood Hits	326	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

NEK11_HUMAN
θ value	8.99809 (rank : 321)	NC score	0.054523 (rank : 1062)
Query Neighborhood Hits	326	Target Neighborhood Hits	1043	Shared Neighborhood Hits	94
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

RSF1_HUMAN
θ value	8.99809 (rank : 322)	NC score	0.087865 (rank : 506)
Query Neighborhood Hits	326	Target Neighborhood Hits	539	Shared Neighborhood Hits	83
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

S12A4_MOUSE
θ value	8.99809 (rank : 323)	NC score	0.003799 (rank : 1229)
Query Neighborhood Hits	326	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIS8, O55069, Q9ET57	Gene names	Slc12a4, Kcc1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).

TAOK2_MOUSE
θ value	8.99809 (rank : 324)	NC score	0.064429 (rank : 864)
Query Neighborhood Hits	326	Target Neighborhood Hits	1373	Shared Neighborhood Hits	127
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

THOC2_HUMAN
θ value	8.99809 (rank : 325)	NC score	0.060144 (rank : 948)
Query Neighborhood Hits	326	Target Neighborhood Hits	337	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

UACA_HUMAN
θ value	8.99809 (rank : 326)	NC score	0.100478 (rank : 386)
Query Neighborhood Hits	326	Target Neighborhood Hits	1622	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

3BP5_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.077630 (rank : 616)
Query Neighborhood Hits	326	Target Neighborhood Hits	375	Shared Neighborhood Hits	71
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

3BP5_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.077729 (rank : 615)
Query Neighborhood Hits	326	Target Neighborhood Hits	346	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

AATK_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.070725 (rank : 724)
Query Neighborhood Hits	326	Target Neighborhood Hits	1243	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AATK_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.073762 (rank : 664)
Query Neighborhood Hits	326	Target Neighborhood Hits	942	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABI2_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.055948 (rank : 1036)
Query Neighborhood Hits	326	Target Neighborhood Hits	350	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.053900 (rank : 1073)
Query Neighborhood Hits	326	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.054363 (rank : 1069)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.050446 (rank : 1156)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABTAP_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.055483 (rank : 1050)
Query Neighborhood Hits	326	Target Neighborhood Hits	290	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ACK1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.078117 (rank : 608)
Query Neighborhood Hits	326	Target Neighborhood Hits	1140	Shared Neighborhood Hits	59
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.078865 (rank : 601)
Query Neighborhood Hits	326	Target Neighborhood Hits	1080	Shared Neighborhood Hits	55
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ADIP_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.092972 (rank : 450)
Query Neighborhood Hits	326	Target Neighborhood Hits	470	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

ADIP_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.082923 (rank : 554)
Query Neighborhood Hits	326	Target Neighborhood Hits	415	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

AFF4_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.057426 (rank : 987)
Query Neighborhood Hits	326	Target Neighborhood Hits	611	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AHI1_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.053038 (rank : 1089)
Query Neighborhood Hits	326	Target Neighborhood Hits	537	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AHI1_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.051519 (rank : 1128)
Query Neighborhood Hits	326	Target Neighborhood Hits	496	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

AKA12_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.102391 (rank : 375)
Query Neighborhood Hits	326	Target Neighborhood Hits	825	Shared Neighborhood Hits	118
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

AL2SB_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.057220 (rank : 998)
Query Neighborhood Hits	326	Target Neighborhood Hits	294	Shared Neighborhood Hits	50
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

ALK_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.076121 (rank : 639)
Query Neighborhood Hits	326	Target Neighborhood Hits	795	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.076538 (rank : 633)
Query Neighborhood Hits	326	Target Neighborhood Hits	811	Shared Neighborhood Hits	42
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

AMOL1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.053067 (rank : 1087)
Query Neighborhood Hits	326	Target Neighborhood Hits	435	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

AMOL2_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.066282 (rank : 822)
Query Neighborhood Hits	326	Target Neighborhood Hits	603	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

AMOL2_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.065164 (rank : 853)
Query Neighborhood Hits	326	Target Neighborhood Hits	591	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

AMOT_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.059719 (rank : 956)
Query Neighborhood Hits	326	Target Neighborhood Hits	712	Shared Neighborhood Hits	79
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

AN30A_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.095260 (rank : 425)
Query Neighborhood Hits	326	Target Neighborhood Hits	1119	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANPRA_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.060552 (rank : 943)
Query Neighborhood Hits	326	Target Neighborhood Hits	612	Shared Neighborhood Hits	39
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRA_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.060565 (rank : 941)
Query Neighborhood Hits	326	Target Neighborhood Hits	600	Shared Neighborhood Hits	39
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRB_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.056632 (rank : 1016)
Query Neighborhood Hits	326	Target Neighborhood Hits	646	Shared Neighborhood Hits	43
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.056740 (rank : 1013)
Query Neighborhood Hits	326	Target Neighborhood Hits	607	Shared Neighborhood Hits	43
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANR18_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.069040 (rank : 759)
Query Neighborhood Hits	326	Target Neighborhood Hits	1106	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR21_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.052790 (rank : 1097)
Query Neighborhood Hits	326	Target Neighborhood Hits	864	Shared Neighborhood Hits	132
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR26_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.100313 (rank : 387)
Query Neighborhood Hits	326	Target Neighborhood Hits	1614	Shared Neighborhood Hits	163
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR26_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.104851 (rank : 354)
Query Neighborhood Hits	326	Target Neighborhood Hits	1554	Shared Neighborhood Hits	159
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

APOA1_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.050342 (rank : 1160)
Query Neighborhood Hits	326	Target Neighborhood Hits	210	Shared Neighborhood Hits	44
SwissProt Accessions	Q00623	Gene names	Apoa1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I).

APOA4_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.058936 (rank : 962)
Query Neighborhood Hits	326	Target Neighborhood Hits	399	Shared Neighborhood Hits	63
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

APOA4_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.068623 (rank : 771)
Query Neighborhood Hits	326	Target Neighborhood Hits	435	Shared Neighborhood Hits	65
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

APOE_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.061163 (rank : 928)
Query Neighborhood Hits	326	Target Neighborhood Hits	319	Shared Neighborhood Hits	53
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

ARAF_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.057246 (rank : 997)
Query Neighborhood Hits	326	Target Neighborhood Hits	924	Shared Neighborhood Hits	45
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.057201 (rank : 999)
Query Neighborhood Hits	326	Target Neighborhood Hits	874	Shared Neighborhood Hits	44
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

ARHG6_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.067341 (rank : 795)
Query Neighborhood Hits	326	Target Neighborhood Hits	376	Shared Neighborhood Hits	62
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.066506 (rank : 818)
Query Neighborhood Hits	326	Target Neighborhood Hits	394	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG7_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.063305 (rank : 890)
Query Neighborhood Hits	326	Target Neighborhood Hits	347	Shared Neighborhood Hits	46
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.072218 (rank : 692)
Query Neighborhood Hits	326	Target Neighborhood Hits	396	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARI4A_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.068828 (rank : 765)
Query Neighborhood Hits	326	Target Neighborhood Hits	434	Shared Neighborhood Hits	67
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ASPP1_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.062298 (rank : 911)
Query Neighborhood Hits	326	Target Neighborhood Hits	956	Shared Neighborhood Hits	101
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.061043 (rank : 932)
Query Neighborhood Hits	326	Target Neighborhood Hits	1244	Shared Neighborhood Hits	108
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.062669 (rank : 902)
Query Neighborhood Hits	326	Target Neighborhood Hits	1156	Shared Neighborhood Hits	105
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

AZI1_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.105874 (rank : 343)
Query Neighborhood Hits	326	Target Neighborhood Hits	1000	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.119790 (rank : 224)
Query Neighborhood Hits	326	Target Neighborhood Hits	990	Shared Neighborhood Hits	121
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BAP29_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.079226 (rank : 592)
Query Neighborhood Hits	326	Target Neighborhood Hits	362	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

BAP29_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.056177 (rank : 1030)
Query Neighborhood Hits	326	Target Neighborhood Hits	285	Shared Neighborhood Hits	60
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.078383 (rank : 607)
Query Neighborhood Hits	326	Target Neighborhood Hits	693	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.087252 (rank : 514)
Query Neighborhood Hits	326	Target Neighborhood Hits	701	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.055078 (rank : 1058)
Query Neighborhood Hits	326	Target Neighborhood Hits	803	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BCAR3_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.178787 (rank : 67)
Query Neighborhood Hits	326	Target Neighborhood Hits	129	Shared Neighborhood Hits	76
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

BCAR3_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.175959 (rank : 69)
Query Neighborhood Hits	326	Target Neighborhood Hits	127	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

BCLF1_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.053138 (rank : 1086)
Query Neighborhood Hits	326	Target Neighborhood Hits	303	Shared Neighborhood Hits	66
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

BCN1_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.051961 (rank : 1115)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	67
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

BCN1_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.050454 (rank : 1155)
Query Neighborhood Hits	326	Target Neighborhood Hits	367	Shared Neighborhood Hits	65
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

BICD2_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.100832 (rank : 383)
Query Neighborhood Hits	326	Target Neighborhood Hits	856	Shared Neighborhood Hits	115
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.099801 (rank : 392)
Query Neighborhood Hits	326	Target Neighborhood Hits	864	Shared Neighborhood Hits	114
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BLK_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.116391 (rank : 259)
Query Neighborhood Hits	326	Target Neighborhood Hits	994	Shared Neighborhood Hits	91
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLNK_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.081907 (rank : 567)
Query Neighborhood Hits	326	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BLNK_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.074924 (rank : 649)
Query Neighborhood Hits	326	Target Neighborhood Hits	296	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BMR1A_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.051616 (rank : 1126)
Query Neighborhood Hits	326	Target Neighborhood Hits	759	Shared Neighborhood Hits	39
SwissProt Accessions	P36894, Q8NEN8	Gene names	BMPR1A, ACVRLK3, ALK3
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen).

BMR1A_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.051616 (rank : 1125)
Query Neighborhood Hits	326	Target Neighborhood Hits	758	Shared Neighborhood Hits	39
SwissProt Accessions	P36895	Gene names	Bmpr1a, Acvrlk3, Bmpr
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor).

BMR1B_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.053225 (rank : 1083)
Query Neighborhood Hits	326	Target Neighborhood Hits	760	Shared Neighborhood Hits	39
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

BMR1B_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.052986 (rank : 1090)
Query Neighborhood Hits	326	Target Neighborhood Hits	758	Shared Neighborhood Hits	39
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

BMX_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.111252 (rank : 300)
Query Neighborhood Hits	326	Target Neighborhood Hits	942	Shared Neighborhood Hits	89
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.109846 (rank : 312)
Query Neighborhood Hits	326	Target Neighborhood Hits	912	Shared Neighborhood Hits	87
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BPA1_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.081427 (rank : 571)
Query Neighborhood Hits	326	Target Neighborhood Hits	1477	Shared Neighborhood Hits	133
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.089144 (rank : 493)
Query Neighborhood Hits	326	Target Neighborhood Hits	1369	Shared Neighborhood Hits	135
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.118867 (rank : 233)
Query Neighborhood Hits	326	Target Neighborhood Hits	1480	Shared Neighborhood Hits	170
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPTF_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.050047 (rank : 1165)
Query Neighborhood Hits	326	Target Neighborhood Hits	786	Shared Neighborhood Hits	89
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRAF1_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.057000 (rank : 1008)
Query Neighborhood Hits	326	Target Neighborhood Hits	883	Shared Neighborhood Hits	46
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BRAP_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.063907 (rank : 875)
Query Neighborhood Hits	326	Target Neighborhood Hits	560	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRD4_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.050021 (rank : 1166)
Query Neighborhood Hits	326	Target Neighborhood Hits	851	Shared Neighborhood Hits	87
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.054475 (rank : 1066)
Query Neighborhood Hits	326	Target Neighborhood Hits	845	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRE1B_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.122906 (rank : 207)
Query Neighborhood Hits	326	Target Neighborhood Hits	1040	Shared Neighborhood Hits	128
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.113615 (rank : 272)
Query Neighborhood Hits	326	Target Neighborhood Hits	970	Shared Neighborhood Hits	115
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BTK_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.118999 (rank : 229)
Query Neighborhood Hits	326	Target Neighborhood Hits	1026	Shared Neighborhood Hits	90
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.118384 (rank : 239)
Query Neighborhood Hits	326	Target Neighborhood Hits	1017	Shared Neighborhood Hits	90
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

C102B_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.093476 (rank : 449)
Query Neighborhood Hits	326	Target Neighborhood Hits	542	Shared Neighborhood Hits	88
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

C8AP2_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.095211 (rank : 426)
Query Neighborhood Hits	326	Target Neighborhood Hits	548	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CA065_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.093584 (rank : 448)
Query Neighborhood Hits	326	Target Neighborhood Hits	469	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CAR10_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.073903 (rank : 662)
Query Neighborhood Hits	326	Target Neighborhood Hits	569	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CAR11_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.089507 (rank : 489)
Query Neighborhood Hits	326	Target Neighborhood Hits	690	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CAR14_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.057508 (rank : 984)
Query Neighborhood Hits	326	Target Neighborhood Hits	449	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CAR14_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.063128 (rank : 895)
Query Neighborhood Hits	326	Target Neighborhood Hits	526	Shared Neighborhood Hits	81
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

CARD9_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.102085 (rank : 378)
Query Neighborhood Hits	326	Target Neighborhood Hits	602	Shared Neighborhood Hits	106
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CASP_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.113307 (rank : 275)
Query Neighborhood Hits	326	Target Neighborhood Hits	1131	Shared Neighborhood Hits	146
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.112464 (rank : 287)
Query Neighborhood Hits	326	Target Neighborhood Hits	1152	Shared Neighborhood Hits	145
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCAR1_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.055355 (rank : 1053)
Query Neighborhood Hits	326	Target Neighborhood Hits	444	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CCD11_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.131707 (rank : 152)
Query Neighborhood Hits	326	Target Neighborhood Hits	822	Shared Neighborhood Hits	133
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD11_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.082068 (rank : 564)
Query Neighborhood Hits	326	Target Neighborhood Hits	498	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD13_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.094773 (rank : 433)
Query Neighborhood Hits	326	Target Neighborhood Hits	721	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD21_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.123767 (rank : 203)
Query Neighborhood Hits	326	Target Neighborhood Hits	1228	Shared Neighborhood Hits	162
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD21_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.124773 (rank : 193)
Query Neighborhood Hits	326	Target Neighborhood Hits	1135	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD27_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.077910 (rank : 609)
Query Neighborhood Hits	326	Target Neighborhood Hits	594	Shared Neighborhood Hits	82
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD27_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.067924 (rank : 787)
Query Neighborhood Hits	326	Target Neighborhood Hits	461	Shared Neighborhood Hits	68
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD38_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.072167 (rank : 694)
Query Neighborhood Hits	326	Target Neighborhood Hits	287	Shared Neighborhood Hits	81
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CCD39_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.106933 (rank : 335)
Query Neighborhood Hits	326	Target Neighborhood Hits	868	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.117998 (rank : 242)
Query Neighborhood Hits	326	Target Neighborhood Hits	1026	Shared Neighborhood Hits	135
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.132174 (rank : 149)
Query Neighborhood Hits	326	Target Neighborhood Hits	1139	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.139405 (rank : 123)
Query Neighborhood Hits	326	Target Neighborhood Hits	1399	Shared Neighborhood Hits	173
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD42_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.088377 (rank : 501)
Query Neighborhood Hits	326	Target Neighborhood Hits	406	Shared Neighborhood Hits	82
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD42_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.065595 (rank : 841)
Query Neighborhood Hits	326	Target Neighborhood Hits	284	Shared Neighborhood Hits	58
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD45_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.114505 (rank : 266)
Query Neighborhood Hits	326	Target Neighborhood Hits	525	Shared Neighborhood Hits	116
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD45_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.106763 (rank : 336)
Query Neighborhood Hits	326	Target Neighborhood Hits	663	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD50_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.081289 (rank : 572)
Query Neighborhood Hits	326	Target Neighborhood Hits	237	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CCD50_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.050926 (rank : 1147)
Query Neighborhood Hits	326	Target Neighborhood Hits	172	Shared Neighborhood Hits	48
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CCD55_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.128509 (rank : 164)
Query Neighborhood Hits	326	Target Neighborhood Hits	513	Shared Neighborhood Hits	110
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD55_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.105590 (rank : 345)
Query Neighborhood Hits	326	Target Neighborhood Hits	519	Shared Neighborhood Hits	99
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD62_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.095739 (rank : 420)
Query Neighborhood Hits	326	Target Neighborhood Hits	631	Shared Neighborhood Hits	99
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD91_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.128069 (rank : 170)
Query Neighborhood Hits	326	Target Neighborhood Hits	868	Shared Neighborhood Hits	148
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CCD91_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.119693 (rank : 225)
Query Neighborhood Hits	326	Target Neighborhood Hits	699	Shared Neighborhood Hits	116
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD93_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.102635 (rank : 374)
Query Neighborhood Hits	326	Target Neighborhood Hits	600	Shared Neighborhood Hits	103
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD93_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.058769 (rank : 965)
Query Neighborhood Hits	326	Target Neighborhood Hits	362	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD96_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.109974 (rank : 310)
Query Neighborhood Hits	326	Target Neighborhood Hits	595	Shared Neighborhood Hits	91
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.100632 (rank : 385)
Query Neighborhood Hits	326	Target Neighborhood Hits	723	Shared Neighborhood Hits	111
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.083116 (rank : 552)
Query Neighborhood Hits	326	Target Neighborhood Hits	717	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.106366 (rank : 340)
Query Neighborhood Hits	326	Target Neighborhood Hits	932	Shared Neighborhood Hits	139
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CCNB3_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.057011 (rank : 1007)
Query Neighborhood Hits	326	Target Neighborhood Hits	368	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CD2AP_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.068871 (rank : 763)
Query Neighborhood Hits	326	Target Neighborhood Hits	315	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.067599 (rank : 790)
Query Neighborhood Hits	326	Target Neighborhood Hits	336	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CDC37_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.112207 (rank : 291)
Query Neighborhood Hits	326	Target Neighborhood Hits	506	Shared Neighborhood Hits	114
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CDC37_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.083150 (rank : 551)
Query Neighborhood Hits	326	Target Neighborhood Hits	359	Shared Neighborhood Hits	83
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CDR2_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.060852 (rank : 937)
Query Neighborhood Hits	326	Target Neighborhood Hits	404	Shared Neighborhood Hits	69
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

CDR2_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.086311 (rank : 525)
Query Neighborhood Hits	326	Target Neighborhood Hits	482	Shared Neighborhood Hits	82
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

CE152_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.117011 (rank : 252)
Query Neighborhood Hits	326	Target Neighborhood Hits	976	Shared Neighborhood Hits	124
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CENPH_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.072177 (rank : 693)
Query Neighborhood Hits	326	Target Neighborhood Hits	335	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

CENPJ_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.121821 (rank : 213)
Query Neighborhood Hits	326	Target Neighborhood Hits	721	Shared Neighborhood Hits	140
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CENPU_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.050410 (rank : 1157)
Query Neighborhood Hits	326	Target Neighborhood Hits	289	Shared Neighborhood Hits	56
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CEP35_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.112982 (rank : 281)
Query Neighborhood Hits	326	Target Neighborhood Hits	811	Shared Neighborhood Hits	124
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CEP55_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.090842 (rank : 471)
Query Neighborhood Hits	326	Target Neighborhood Hits	504	Shared Neighborhood Hits	87
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP55_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.102859 (rank : 371)
Query Neighborhood Hits	326	Target Neighborhood Hits	693	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP57_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.073886 (rank : 663)
Query Neighborhood Hits	326	Target Neighborhood Hits	576	Shared Neighborhood Hits	94
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

CEP57_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.079300 (rank : 589)
Query Neighborhood Hits	326	Target Neighborhood Hits	580	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CEP63_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.107176 (rank : 334)
Query Neighborhood Hits	326	Target Neighborhood Hits	1005	Shared Neighborhood Hits	120
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CEP70_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.086117 (rank : 530)
Query Neighborhood Hits	326	Target Neighborhood Hits	432	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

CEP70_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.077042 (rank : 625)
Query Neighborhood Hits	326	Target Neighborhood Hits	532	Shared Neighborhood Hits	87
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

CF010_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.105789 (rank : 344)
Query Neighborhood Hits	326	Target Neighborhood Hits	329	Shared Neighborhood Hits	84
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CF060_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.117650 (rank : 245)
Query Neighborhood Hits	326	Target Neighborhood Hits	1270	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CF152_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.108399 (rank : 324)
Query Neighborhood Hits	326	Target Neighborhood Hits	704	Shared Neighborhood Hits	123
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CF152_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.096402 (rank : 414)
Query Neighborhood Hits	326	Target Neighborhood Hits	597	Shared Neighborhood Hits	100
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CF182_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.071813 (rank : 705)
Query Neighborhood Hits	326	Target Neighborhood Hits	474	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

CF182_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.085262 (rank : 539)
Query Neighborhood Hits	326	Target Neighborhood Hits	551	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CHCH3_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.062089 (rank : 914)
Query Neighborhood Hits	326	Target Neighborhood Hits	249	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CHIN_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.108037 (rank : 328)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.110980 (rank : 303)
Query Neighborhood Hits	326	Target Neighborhood Hits	229	Shared Neighborhood Hits	77
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CI039_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.151184 (rank : 96)
Query Neighborhood Hits	326	Target Neighborhood Hits	1171	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.127443 (rank : 176)
Query Neighborhood Hits	326	Target Neighborhood Hits	1088	Shared Neighborhood Hits	153
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CING_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.124764 (rank : 194)
Query Neighborhood Hits	326	Target Neighborhood Hits	1432	Shared Neighborhood Hits	167
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CIP4_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.111808 (rank : 295)
Query Neighborhood Hits	326	Target Neighborhood Hits	374	Shared Neighborhood Hits	83
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CIR_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.051223 (rank : 1134)
Query Neighborhood Hits	326	Target Neighborhood Hits	255	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

CISH_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.120067 (rank : 222)
Query Neighborhood Hits	326	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NSE2, Q9NS38, Q9Y5R1	Gene names	CISH, G18
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS) (Protein G18).

CISH_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.120262 (rank : 220)
Query Neighborhood Hits	326	Target Neighborhood Hits	94	Shared Neighborhood Hits	55
SwissProt Accessions	Q62225, Q3TC70	Gene names	Cish, Cis
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS).

CJ049_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.051715 (rank : 1122)
Query Neighborhood Hits	326	Target Neighborhood Hits	90	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

CJ068_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.103177 (rank : 366)
Query Neighborhood Hits	326	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CJ118_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.107719 (rank : 331)
Query Neighborhood Hits	326	Target Neighborhood Hits	1132	Shared Neighborhood Hits	143
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CK5P2_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.124925 (rank : 192)
Query Neighborhood Hits	326	Target Neighborhood Hits	1151	Shared Neighborhood Hits	147
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CKAP4_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.081945 (rank : 565)
Query Neighborhood Hits	326	Target Neighborhood Hits	592	Shared Neighborhood Hits	86
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CKAP4_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.079222 (rank : 593)
Query Neighborhood Hits	326	Target Neighborhood Hits	596	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CLC4F_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.055339 (rank : 1054)
Query Neighborhood Hits	326	Target Neighborhood Hits	513	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

CLCB_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.082182 (rank : 563)
Query Neighborhood Hits	326	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q6IRU5, Q8BR04, Q8CDX9, Q9CV35	Gene names	Cltb
Domain Architecture	No domain graphic available
Description	Clathrin light chain B (Lcb).

CLUA1_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.051209 (rank : 1137)
Query Neighborhood Hits	326	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

CN044_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.061989 (rank : 915)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

CN045_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.052874 (rank : 1095)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	44
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

CNTRB_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.122787 (rank : 208)
Query Neighborhood Hits	326	Target Neighborhood Hits	1029	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP135_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.115711 (rank : 263)
Query Neighborhood Hits	326	Target Neighborhood Hits	1290	Shared Neighborhood Hits	159
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP135_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.119353 (rank : 227)
Query Neighborhood Hits	326	Target Neighborhood Hits	1278	Shared Neighborhood Hits	156
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CR034_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.072071 (rank : 697)
Query Neighborhood Hits	326	Target Neighborhood Hits	538	Shared Neighborhood Hits	80
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CR034_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.087634 (rank : 509)
Query Neighborhood Hits	326	Target Neighborhood Hits	643	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CRCM_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.073252 (rank : 673)
Query Neighborhood Hits	326	Target Neighborhood Hits	520	Shared Neighborhood Hits	79
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

CROCC_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.098659 (rank : 397)
Query Neighborhood Hits	326	Target Neighborhood Hits	1409	Shared Neighborhood Hits	133
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.117635 (rank : 246)
Query Neighborhood Hits	326	Target Neighborhood Hits	1460	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CS029_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.084264 (rank : 543)
Query Neighborhood Hits	326	Target Neighborhood Hits	329	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

CS029_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.056316 (rank : 1023)
Query Neighborhood Hits	326	Target Neighborhood Hits	201	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

CSF1R_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.071857 (rank : 704)
Query Neighborhood Hits	326	Target Neighborhood Hits	943	Shared Neighborhood Hits	42
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF1R_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.069771 (rank : 743)
Query Neighborhood Hits	326	Target Neighborhood Hits	983	Shared Neighborhood Hits	42
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CT096_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.069941 (rank : 736)
Query Neighborhood Hits	326	Target Neighborhood Hits	438	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT116_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.076685 (rank : 631)
Query Neighborhood Hits	326	Target Neighborhood Hits	294	Shared Neighborhood Hits	55
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

CT2NL_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.137830 (rank : 130)
Query Neighborhood Hits	326	Target Neighborhood Hits	1059	Shared Neighborhood Hits	166
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.124364 (rank : 199)
Query Neighborhood Hits	326	Target Neighborhood Hits	902	Shared Neighborhood Hits	154
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CTGE2_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.065578 (rank : 845)
Query Neighborhood Hits	326	Target Neighborhood Hits	594	Shared Neighborhood Hits	78
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

CTGE5_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.086987 (rank : 518)
Query Neighborhood Hits	326	Target Neighborhood Hits	800	Shared Neighborhood Hits	119
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

CTGE5_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.090617 (rank : 473)
Query Neighborhood Hits	326	Target Neighborhood Hits	928	Shared Neighborhood Hits	126
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CTGE6_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.076401 (rank : 634)
Query Neighborhood Hits	326	Target Neighborhood Hits	650	Shared Neighborhood Hits	101
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

CTRO_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.075940 (rank : 641)
Query Neighborhood Hits	326	Target Neighborhood Hits	2092	Shared Neighborhood Hits	179
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.088495 (rank : 498)
Query Neighborhood Hits	326	Target Neighborhood Hits	2344	Shared Neighborhood Hits	206
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CU013_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.067612 (rank : 789)
Query Neighborhood Hits	326	Target Neighborhood Hits	405	Shared Neighborhood Hits	66
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CUTL1_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.104256 (rank : 359)
Query Neighborhood Hits	326	Target Neighborhood Hits	1574	Shared Neighborhood Hits	154
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.102248 (rank : 376)
Query Neighborhood Hits	326	Target Neighborhood Hits	1620	Shared Neighborhood Hits	155
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CYLN2_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.113187 (rank : 278)
Query Neighborhood Hits	326	Target Neighborhood Hits	1004	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.104948 (rank : 353)
Query Neighborhood Hits	326	Target Neighborhood Hits	1002	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CYTSA_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.097054 (rank : 411)
Query Neighborhood Hits	326	Target Neighborhood Hits	1138	Shared Neighborhood Hits	131
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.097765 (rank : 401)
Query Neighborhood Hits	326	Target Neighborhood Hits	1104	Shared Neighborhood Hits	134
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DBNL_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.051222 (rank : 1135)
Query Neighborhood Hits	326	Target Neighborhood Hits	244	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.050577 (rank : 1153)
Query Neighborhood Hits	326	Target Neighborhood Hits	306	Shared Neighborhood Hits	47
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DDR1_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.072850 (rank : 680)
Query Neighborhood Hits	326	Target Neighborhood Hits	819	Shared Neighborhood Hits	44
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.073240 (rank : 675)
Query Neighborhood Hits	326	Target Neighborhood Hits	818	Shared Neighborhood Hits	44
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.071612 (rank : 708)
Query Neighborhood Hits	326	Target Neighborhood Hits	818	Shared Neighborhood Hits	42
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.071261 (rank : 716)
Query Neighborhood Hits	326	Target Neighborhood Hits	813	Shared Neighborhood Hits	42
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DEK_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.057951 (rank : 976)
Query Neighborhood Hits	326	Target Neighborhood Hits	280	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DESP_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.125585 (rank : 187)
Query Neighborhood Hits	326	Target Neighborhood Hits	1470	Shared Neighborhood Hits	158
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DLG5_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.078522 (rank : 605)
Query Neighborhood Hits	326	Target Neighborhood Hits	1088	Shared Neighborhood Hits	116
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DMD_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.082796 (rank : 558)
Query Neighborhood Hits	326	Target Neighborhood Hits	1135	Shared Neighborhood Hits	136
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.089430 (rank : 490)
Query Neighborhood Hits	326	Target Neighborhood Hits	1111	Shared Neighborhood Hits	139
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DMN_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.086905 (rank : 519)
Query Neighborhood Hits	326	Target Neighborhood Hits	690	Shared Neighborhood Hits	143
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

DMP1_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.063407 (rank : 887)
Query Neighborhood Hits	326	Target Neighborhood Hits	491	Shared Neighborhood Hits	63
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DNJC8_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.096492 (rank : 413)
Query Neighborhood Hits	326	Target Neighborhood Hits	380	Shared Neighborhood Hits	104
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.100265 (rank : 388)
Query Neighborhood Hits	326	Target Neighborhood Hits	392	Shared Neighborhood Hits	107
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

DNMBP_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.063241 (rank : 891)
Query Neighborhood Hits	326	Target Neighborhood Hits	413	Shared Neighborhood Hits	60
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.059916 (rank : 951)
Query Neighborhood Hits	326	Target Neighborhood Hits	435	Shared Neighborhood Hits	58
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMT1_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.062393 (rank : 908)
Query Neighborhood Hits	326	Target Neighborhood Hits	401	Shared Neighborhood Hits	86
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DREB_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.063154 (rank : 894)
Query Neighborhood Hits	326	Target Neighborhood Hits	450	Shared Neighborhood Hits	71
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DREB_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.067296 (rank : 798)
Query Neighborhood Hits	326	Target Neighborhood Hits	446	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DYHC_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.061311 (rank : 923)
Query Neighborhood Hits	326	Target Neighborhood Hits	733	Shared Neighborhood Hits	114
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.061008 (rank : 933)
Query Neighborhood Hits	326	Target Neighborhood Hits	729	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYNA_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.094007 (rank : 443)
Query Neighborhood Hits	326	Target Neighborhood Hits	1194	Shared Neighborhood Hits	133
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.092015 (rank : 460)
Query Neighborhood Hits	326	Target Neighborhood Hits	1084	Shared Neighborhood Hits	124
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

DZIP1_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.066742 (rank : 811)
Query Neighborhood Hits	326	Target Neighborhood Hits	675	Shared Neighborhood Hits	69
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

DZIP1_MOUSE
θ value	θ > 10 (rank : 549)	NC score	0.071246 (rank : 718)
Query Neighborhood Hits	326	Target Neighborhood Hits	530	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

EGFR_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.070668 (rank : 727)
Query Neighborhood Hits	326	Target Neighborhood Hits	939	Shared Neighborhood Hits	42
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.070708 (rank : 726)
Query Neighborhood Hits	326	Target Neighborhood Hits	927	Shared Neighborhood Hits	42
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ELOA1_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.077798 (rank : 613)
Query Neighborhood Hits	326	Target Neighborhood Hits	388	Shared Neighborhood Hits	77
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ENAH_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.060319 (rank : 945)
Query Neighborhood Hits	326	Target Neighborhood Hits	784	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAH_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.056080 (rank : 1032)
Query Neighborhood Hits	326	Target Neighborhood Hits	919	Shared Neighborhood Hits	81
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP15R_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.097200 (rank : 408)
Query Neighborhood Hits	326	Target Neighborhood Hits	1083	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.097756 (rank : 402)
Query Neighborhood Hits	326	Target Neighborhood Hits	1135	Shared Neighborhood Hits	145
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.071979 (rank : 699)
Query Neighborhood Hits	326	Target Neighborhood Hits	1021	Shared Neighborhood Hits	105
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.074877 (rank : 650)
Query Neighborhood Hits	326	Target Neighborhood Hits	820	Shared Neighborhood Hits	81
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EPHA1_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.068850 (rank : 764)
Query Neighborhood Hits	326	Target Neighborhood Hits	997	Shared Neighborhood Hits	41
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA1_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.069958 (rank : 735)
Query Neighborhood Hits	326	Target Neighborhood Hits	958	Shared Neighborhood Hits	41
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA2_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.067052 (rank : 805)
Query Neighborhood Hits	326	Target Neighborhood Hits	1021	Shared Neighborhood Hits	41
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA2_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.067080 (rank : 804)
Query Neighborhood Hits	326	Target Neighborhood Hits	1020	Shared Neighborhood Hits	41
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA3_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.065398 (rank : 847)
Query Neighborhood Hits	326	Target Neighborhood Hits	1005	Shared Neighborhood Hits	41
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA3_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.065616 (rank : 839)
Query Neighborhood Hits	326	Target Neighborhood Hits	1009	Shared Neighborhood Hits	41
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA4_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.066049 (rank : 831)
Query Neighborhood Hits	326	Target Neighborhood Hits	975	Shared Neighborhood Hits	41
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.066011 (rank : 834)
Query Neighborhood Hits	326	Target Neighborhood Hits	982	Shared Neighborhood Hits	41
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA5_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.065594 (rank : 842)
Query Neighborhood Hits	326	Target Neighborhood Hits	1009	Shared Neighborhood Hits	41
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA5_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.068628 (rank : 770)
Query Neighborhood Hits	326	Target Neighborhood Hits	950	Shared Neighborhood Hits	41
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHA6_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.069160 (rank : 756)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA6_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.069142 (rank : 757)
Query Neighborhood Hits	326	Target Neighborhood Hits	946	Shared Neighborhood Hits	41
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA7_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.064688 (rank : 860)
Query Neighborhood Hits	326	Target Neighborhood Hits	1053	Shared Neighborhood Hits	41
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA7_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.064643 (rank : 862)
Query Neighborhood Hits	326	Target Neighborhood Hits	1025	Shared Neighborhood Hits	41
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHA8_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.066363 (rank : 820)
Query Neighborhood Hits	326	Target Neighborhood Hits	956	Shared Neighborhood Hits	43
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.066823 (rank : 808)
Query Neighborhood Hits	326	Target Neighborhood Hits	969	Shared Neighborhood Hits	43
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

EPHAA_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.070944 (rank : 722)
Query Neighborhood Hits	326	Target Neighborhood Hits	960	Shared Neighborhood Hits	40
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB1_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.065614 (rank : 840)
Query Neighborhood Hits	326	Target Neighborhood Hits	988	Shared Neighborhood Hits	41
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHB2_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.066124 (rank : 829)
Query Neighborhood Hits	326	Target Neighborhood Hits	983	Shared Neighborhood Hits	41
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.066149 (rank : 828)
Query Neighborhood Hits	326	Target Neighborhood Hits	982	Shared Neighborhood Hits	41
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB3_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.066794 (rank : 810)
Query Neighborhood Hits	326	Target Neighborhood Hits	996	Shared Neighborhood Hits	41
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB3_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.066893 (rank : 806)
Query Neighborhood Hits	326	Target Neighborhood Hits	996	Shared Neighborhood Hits	41
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHB4_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.066267 (rank : 823)
Query Neighborhood Hits	326	Target Neighborhood Hits	1056	Shared Neighborhood Hits	41
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB4_MOUSE
θ value	θ > 10 (rank : 582)	NC score	0.066028 (rank : 832)
Query Neighborhood Hits	326	Target Neighborhood Hits	1013	Shared Neighborhood Hits	41
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHB6_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.067574 (rank : 791)
Query Neighborhood Hits	326	Target Neighborhood Hits	912	Shared Neighborhood Hits	37
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.068025 (rank : 784)
Query Neighborhood Hits	326	Target Neighborhood Hits	906	Shared Neighborhood Hits	38
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

ERBB2_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.071481 (rank : 712)
Query Neighborhood Hits	326	Target Neighborhood Hits	1073	Shared Neighborhood Hits	44
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.071454 (rank : 713)
Query Neighborhood Hits	326	Target Neighborhood Hits	918	Shared Neighborhood Hits	42
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.071919 (rank : 701)
Query Neighborhood Hits	326	Target Neighborhood Hits	918	Shared Neighborhood Hits	41
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.071964 (rank : 700)
Query Neighborhood Hits	326	Target Neighborhood Hits	898	Shared Neighborhood Hits	41
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.071017 (rank : 721)
Query Neighborhood Hits	326	Target Neighborhood Hits	910	Shared Neighborhood Hits	41
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ERC2_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.107387 (rank : 333)
Query Neighborhood Hits	326	Target Neighborhood Hits	1156	Shared Neighborhood Hits	140
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.106734 (rank : 337)
Query Neighborhood Hits	326	Target Neighborhood Hits	1166	Shared Neighborhood Hits	143
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ESCO1_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.065364 (rank : 848)
Query Neighborhood Hits	326	Target Neighborhood Hits	361	Shared Neighborhood Hits	77
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

EVPL_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.109563 (rank : 314)
Query Neighborhood Hits	326	Target Neighborhood Hits	895	Shared Neighborhood Hits	121
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EZRI_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.077488 (rank : 621)
Query Neighborhood Hits	326	Target Neighborhood Hits	663	Shared Neighborhood Hits	104
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.077889 (rank : 611)
Query Neighborhood Hits	326	Target Neighborhood Hits	693	Shared Neighborhood Hits	110
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FA50A_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.050104 (rank : 1163)
Query Neighborhood Hits	326	Target Neighborhood Hits	293	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

FAK1_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.072087 (rank : 696)
Query Neighborhood Hits	326	Target Neighborhood Hits	850	Shared Neighborhood Hits	42
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.072017 (rank : 698)
Query Neighborhood Hits	326	Target Neighborhood Hits	850	Shared Neighborhood Hits	41
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.074453 (rank : 655)
Query Neighborhood Hits	326	Target Neighborhood Hits	847	Shared Neighborhood Hits	46
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.074123 (rank : 659)
Query Neighborhood Hits	326	Target Neighborhood Hits	851	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FGFR1_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.064774 (rank : 856)
Query Neighborhood Hits	326	Target Neighborhood Hits	1069	Shared Neighborhood Hits	42
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.064746 (rank : 857)
Query Neighborhood Hits	326	Target Neighborhood Hits	1068	Shared Neighborhood Hits	42
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FGFR2_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.065593 (rank : 843)
Query Neighborhood Hits	326	Target Neighborhood Hits	1062	Shared Neighborhood Hits	43
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

FGFR2_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.065786 (rank : 838)
Query Neighborhood Hits	326	Target Neighborhood Hits	1062	Shared Neighborhood Hits	43
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

FGFR3_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.065542 (rank : 846)
Query Neighborhood Hits	326	Target Neighborhood Hits	1042	Shared Neighborhood Hits	41
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FGFR3_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.065304 (rank : 851)
Query Neighborhood Hits	326	Target Neighborhood Hits	1059	Shared Neighborhood Hits	43
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

FGFR4_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.067082 (rank : 803)
Query Neighborhood Hits	326	Target Neighborhood Hits	1037	Shared Neighborhood Hits	41
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FGFR4_MOUSE
θ value	θ > 10 (rank : 608)	NC score	0.068316 (rank : 776)
Query Neighborhood Hits	326	Target Neighborhood Hits	1026	Shared Neighborhood Hits	41
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FLIP1_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.113885 (rank : 269)
Query Neighborhood Hits	326	Target Neighborhood Hits	1405	Shared Neighborhood Hits	157
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.103441 (rank : 364)
Query Neighborhood Hits	326	Target Neighborhood Hits	1176	Shared Neighborhood Hits	134
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLT3_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.072827 (rank : 684)
Query Neighborhood Hits	326	Target Neighborhood Hits	843	Shared Neighborhood Hits	42
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

FLT3_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.072643 (rank : 686)
Query Neighborhood Hits	326	Target Neighborhood Hits	847	Shared Neighborhood Hits	41
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FNBP2_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.050899 (rank : 1148)
Query Neighborhood Hits	326	Target Neighborhood Hits	432	Shared Neighborhood Hits	76
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

FYCO1_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.090445 (rank : 476)
Query Neighborhood Hits	326	Target Neighborhood Hits	1149	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYCO1_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.091971 (rank : 462)
Query Neighborhood Hits	326	Target Neighborhood Hits	1059	Shared Neighborhood Hits	107
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

FYN_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.133943 (rank : 143)
Query Neighborhood Hits	326	Target Neighborhood Hits	1073	Shared Neighborhood Hits	96
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GAS8_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.120443 (rank : 219)
Query Neighborhood Hits	326	Target Neighborhood Hits	819	Shared Neighborhood Hits	125
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GAS8_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.111801 (rank : 296)
Query Neighborhood Hits	326	Target Neighborhood Hits	622	Shared Neighborhood Hits	112
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GBP1_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.051045 (rank : 1143)
Query Neighborhood Hits	326	Target Neighborhood Hits	339	Shared Neighborhood Hits	65
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

GCC1_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.094465 (rank : 436)
Query Neighborhood Hits	326	Target Neighborhood Hits	887	Shared Neighborhood Hits	106
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.097557 (rank : 404)
Query Neighborhood Hits	326	Target Neighborhood Hits	777	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC2_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.112155 (rank : 292)
Query Neighborhood Hits	326	Target Neighborhood Hits	1558	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GCC2_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.118392 (rank : 238)
Query Neighborhood Hits	326	Target Neighborhood Hits	1619	Shared Neighborhood Hits	160
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GCP60_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.067465 (rank : 792)
Query Neighborhood Hits	326	Target Neighborhood Hits	419	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GCP60_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.064424 (rank : 865)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

GFAP_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.058499 (rank : 971)
Query Neighborhood Hits	326	Target Neighborhood Hits	723	Shared Neighborhood Hits	106
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GFAP_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.058113 (rank : 974)
Query Neighborhood Hits	326	Target Neighborhood Hits	725	Shared Neighborhood Hits	99
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GLE1_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.094217 (rank : 438)
Query Neighborhood Hits	326	Target Neighborhood Hits	445	Shared Neighborhood Hits	92
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

GLE1_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.092323 (rank : 457)
Query Neighborhood Hits	326	Target Neighborhood Hits	504	Shared Neighborhood Hits	103
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

GOG8A_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.087507 (rank : 511)
Query Neighborhood Hits	326	Target Neighborhood Hits	635	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA1_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.111579 (rank : 299)
Query Neighborhood Hits	326	Target Neighborhood Hits	1222	Shared Neighborhood Hits	132
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.086232 (rank : 528)
Query Neighborhood Hits	326	Target Neighborhood Hits	856	Shared Neighborhood Hits	94
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA2_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.097823 (rank : 400)
Query Neighborhood Hits	326	Target Neighborhood Hits	944	Shared Neighborhood Hits	110
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.112830 (rank : 283)
Query Neighborhood Hits	326	Target Neighborhood Hits	1437	Shared Neighborhood Hits	149
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA4_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.134404 (rank : 138)
Query Neighborhood Hits	326	Target Neighborhood Hits	2034	Shared Neighborhood Hits	191
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGA4_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.127609 (rank : 174)
Query Neighborhood Hits	326	Target Neighborhood Hits	1939	Shared Neighborhood Hits	187
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.113489 (rank : 273)
Query Neighborhood Hits	326	Target Neighborhood Hits	1168	Shared Neighborhood Hits	147
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA5_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.127595 (rank : 175)
Query Neighborhood Hits	326	Target Neighborhood Hits	1434	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GP73_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.061542 (rank : 919)
Query Neighborhood Hits	326	Target Neighborhood Hits	309	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

GP73_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.086355 (rank : 524)
Query Neighborhood Hits	326	Target Neighborhood Hits	506	Shared Neighborhood Hits	93
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

GRAP1_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.095008 (rank : 430)
Query Neighborhood Hits	326	Target Neighborhood Hits	944	Shared Neighborhood Hits	116
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GRAP1_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.117560 (rank : 247)
Query Neighborhood Hits	326	Target Neighborhood Hits	1234	Shared Neighborhood Hits	154
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRAP_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.276641 (rank : 35)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	87
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.278531 (rank : 33)
Query Neighborhood Hits	326	Target Neighborhood Hits	309	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB10_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.170704 (rank : 74)
Query Neighborhood Hits	326	Target Neighborhood Hits	147	Shared Neighborhood Hits	80
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.165291 (rank : 77)
Query Neighborhood Hits	326	Target Neighborhood Hits	156	Shared Neighborhood Hits	79
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB14_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.210224 (rank : 58)
Query Neighborhood Hits	326	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB14_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.207032 (rank : 61)
Query Neighborhood Hits	326	Target Neighborhood Hits	149	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.217179 (rank : 55)
Query Neighborhood Hits	326	Target Neighborhood Hits	156	Shared Neighborhood Hits	83
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GUC2C_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.056253 (rank : 1026)
Query Neighborhood Hits	326	Target Neighborhood Hits	624	Shared Neighborhood Hits	35
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2D_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.051213 (rank : 1136)
Query Neighborhood Hits	326	Target Neighborhood Hits	715	Shared Neighborhood Hits	40
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

GUC2E_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.052065 (rank : 1111)
Query Neighborhood Hits	326	Target Neighborhood Hits	692	Shared Neighborhood Hits	39
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

GUC2F_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.061304 (rank : 925)
Query Neighborhood Hits	326	Target Neighborhood Hits	740	Shared Neighborhood Hits	39
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

HAP1_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.082409 (rank : 560)
Query Neighborhood Hits	326	Target Neighborhood Hits	606	Shared Neighborhood Hits	90
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HAP1_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.062567 (rank : 906)
Query Neighborhood Hits	326	Target Neighborhood Hits	388	Shared Neighborhood Hits	64
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

HC127_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.052100 (rank : 1109)
Query Neighborhood Hits	326	Target Neighborhood Hits	292	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.052100 (rank : 1110)
Query Neighborhood Hits	326	Target Neighborhood Hits	292	Shared Neighborhood Hits	60
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

HCK_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.125744 (rank : 185)
Query Neighborhood Hits	326	Target Neighborhood Hits	1029	Shared Neighborhood Hits	95
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HCLS1_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.051095 (rank : 1141)
Query Neighborhood Hits	326	Target Neighborhood Hits	358	Shared Neighborhood Hits	36
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.055106 (rank : 1057)
Query Neighborhood Hits	326	Target Neighborhood Hits	329	Shared Neighborhood Hits	42
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HIP1R_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.086103 (rank : 532)
Query Neighborhood Hits	326	Target Neighborhood Hits	809	Shared Neighborhood Hits	109
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.111592 (rank : 298)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	137
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.109383 (rank : 319)
Query Neighborhood Hits	326	Target Neighborhood Hits	1016	Shared Neighborhood Hits	135
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HM20A_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.051820 (rank : 1117)
Query Neighborhood Hits	326	Target Neighborhood Hits	343	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.052810 (rank : 1096)
Query Neighborhood Hits	326	Target Neighborhood Hits	348	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

HMMR_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.097659 (rank : 403)
Query Neighborhood Hits	326	Target Neighborhood Hits	1082	Shared Neighborhood Hits	121
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 667)	NC score	0.111917 (rank : 294)
Query Neighborhood Hits	326	Target Neighborhood Hits	1178	Shared Neighborhood Hits	137
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOME1_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.055877 (rank : 1038)
Query Neighborhood Hits	326	Target Neighborhood Hits	630	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

HOME2_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.065802 (rank : 836)
Query Neighborhood Hits	326	Target Neighborhood Hits	532	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

HOME2_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.113674 (rank : 271)
Query Neighborhood Hits	326	Target Neighborhood Hits	882	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

HOOK1_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.083910 (rank : 544)
Query Neighborhood Hits	326	Target Neighborhood Hits	942	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.082800 (rank : 557)
Query Neighborhood Hits	326	Target Neighborhood Hits	910	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.077017 (rank : 626)
Query Neighborhood Hits	326	Target Neighborhood Hits	714	Shared Neighborhood Hits	98
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

HOOK2_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.076366 (rank : 636)
Query Neighborhood Hits	326	Target Neighborhood Hits	736	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

HOOK3_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.095662 (rank : 422)
Query Neighborhood Hits	326	Target Neighborhood Hits	1070	Shared Neighborhood Hits	125
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.092737 (rank : 451)
Query Neighborhood Hits	326	Target Neighborhood Hits	1007	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

IDLC_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.073736 (rank : 665)
Query Neighborhood Hits	326	Target Neighborhood Hits	348	Shared Neighborhood Hits	77
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

IDLC_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.074665 (rank : 653)
Query Neighborhood Hits	326	Target Neighborhood Hits	321	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

IFT74_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.105143 (rank : 348)
Query Neighborhood Hits	326	Target Neighborhood Hits	949	Shared Neighborhood Hits	121
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.100052 (rank : 389)
Query Neighborhood Hits	326	Target Neighborhood Hits	939	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.113151 (rank : 279)
Query Neighborhood Hits	326	Target Neighborhood Hits	893	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 682)	NC score	0.127309 (rank : 177)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	136
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IGF1R_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.071916 (rank : 702)
Query Neighborhood Hits	326	Target Neighborhood Hits	977	Shared Neighborhood Hits	42
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 684)	NC score	0.071734 (rank : 707)
Query Neighborhood Hits	326	Target Neighborhood Hits	973	Shared Neighborhood Hits	41
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

ILK1_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.060140 (rank : 949)
Query Neighborhood Hits	326	Target Neighborhood Hits	857	Shared Neighborhood Hits	43
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.059784 (rank : 954)
Query Neighborhood Hits	326	Target Neighborhood Hits	848	Shared Neighborhood Hits	43
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
θ value	θ > 10 (rank : 687)	NC score	0.060791 (rank : 939)
Query Neighborhood Hits	326	Target Neighborhood Hits	858	Shared Neighborhood Hits	43
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

IMMT_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.086059 (rank : 533)
Query Neighborhood Hits	326	Target Neighborhood Hits	494	Shared Neighborhood Hits	97
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

IMMT_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.056084 (rank : 1031)
Query Neighborhood Hits	326	Target Neighborhood Hits	326	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

INSRR_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.071498 (rank : 711)
Query Neighborhood Hits	326	Target Neighborhood Hits	950	Shared Neighborhood Hits	41
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 691)	NC score	0.071307 (rank : 714)
Query Neighborhood Hits	326	Target Neighborhood Hits	961	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.070355 (rank : 731)
Query Neighborhood Hits	326	Target Neighborhood Hits	963	Shared Neighborhood Hits	41
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.069884 (rank : 738)
Query Neighborhood Hits	326	Target Neighborhood Hits	968	Shared Neighborhood Hits	41
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INVO_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.082815 (rank : 556)
Query Neighborhood Hits	326	Target Neighborhood Hits	636	Shared Neighborhood Hits	69
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.081746 (rank : 569)
Query Neighborhood Hits	326	Target Neighborhood Hits	474	Shared Neighborhood Hits	72
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

IRAK1_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.053040 (rank : 1088)
Query Neighborhood Hits	326	Target Neighborhood Hits	820	Shared Neighborhood Hits	41
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	θ > 10 (rank : 697)	NC score	0.056069 (rank : 1033)
Query Neighborhood Hits	326	Target Neighborhood Hits	784	Shared Neighborhood Hits	42
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

IRAK3_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.051518 (rank : 1129)
Query Neighborhood Hits	326	Target Neighborhood Hits	644	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK3_MOUSE
θ value	θ > 10 (rank : 699)	NC score	0.051124 (rank : 1140)
Query Neighborhood Hits	326	Target Neighborhood Hits	628	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK4_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.051054 (rank : 1142)
Query Neighborhood Hits	326	Target Neighborhood Hits	816	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

ITK_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.111722 (rank : 297)
Query Neighborhood Hits	326	Target Neighborhood Hits	1016	Shared Neighborhood Hits	95
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITSN1_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.132946 (rank : 147)
Query Neighborhood Hits	326	Target Neighborhood Hits	1757	Shared Neighborhood Hits	203
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	θ > 10 (rank : 703)	NC score	0.140190 (rank : 120)
Query Neighborhood Hits	326	Target Neighborhood Hits	1669	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

IWS1_HUMAN
θ value	θ > 10 (rank : 704)	NC score	0.113099 (rank : 280)
Query Neighborhood Hits	326	Target Neighborhood Hits	1241	Shared Neighborhood Hits	124
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 705)	NC score	0.087315 (rank : 513)
Query Neighborhood Hits	326	Target Neighborhood Hits	1258	Shared Neighborhood Hits	110
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JAK1_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.067361 (rank : 794)
Query Neighborhood Hits	326	Target Neighborhood Hits	858	Shared Neighborhood Hits	46
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_MOUSE
θ value	θ > 10 (rank : 707)	NC score	0.068344 (rank : 775)
Query Neighborhood Hits	326	Target Neighborhood Hits	854	Shared Neighborhood Hits	47
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK2_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.063422 (rank : 884)
Query Neighborhood Hits	326	Target Neighborhood Hits	847	Shared Neighborhood Hits	44
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK2_MOUSE
θ value	θ > 10 (rank : 709)	NC score	0.063840 (rank : 877)
Query Neighborhood Hits	326	Target Neighborhood Hits	839	Shared Neighborhood Hits	43
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK3_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.064167 (rank : 871)
Query Neighborhood Hits	326	Target Neighborhood Hits	827	Shared Neighborhood Hits	41
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

JAK3_MOUSE
θ value	θ > 10 (rank : 711)	NC score	0.062113 (rank : 913)
Query Neighborhood Hits	326	Target Neighborhood Hits	821	Shared Neighborhood Hits	41
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

JIP3_HUMAN
θ value	θ > 10 (rank : 712)	NC score	0.066002 (rank : 835)
Query Neighborhood Hits	326	Target Neighborhood Hits	1039	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

JIP3_MOUSE
θ value	θ > 10 (rank : 713)	NC score	0.063411 (rank : 886)
Query Neighborhood Hits	326	Target Neighborhood Hits	759	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

K0494_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.055568 (rank : 1044)
Query Neighborhood Hits	326	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

K0552_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.064259 (rank : 869)
Query Neighborhood Hits	326	Target Neighborhood Hits	442	Shared Neighborhood Hits	67
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

K0555_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.132124 (rank : 150)
Query Neighborhood Hits	326	Target Neighborhood Hits	880	Shared Neighborhood Hits	132
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

K0586_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.056310 (rank : 1024)
Query Neighborhood Hits	326	Target Neighborhood Hits	311	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

K0831_MOUSE
θ value	θ > 10 (rank : 718)	NC score	0.061807 (rank : 918)
Query Neighborhood Hits	326	Target Neighborhood Hits	277	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

KI21A_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.075428 (rank : 645)
Query Neighborhood Hits	326	Target Neighborhood Hits	1317	Shared Neighborhood Hits	148
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KI21B_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.054555 (rank : 1061)
Query Neighborhood Hits	326	Target Neighborhood Hits	1017	Shared Neighborhood Hits	104
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

KI21B_MOUSE
θ value	θ > 10 (rank : 721)	NC score	0.055523 (rank : 1047)
Query Neighborhood Hits	326	Target Neighborhood Hits	997	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

KI67_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.080413 (rank : 580)
Query Neighborhood Hits	326	Target Neighborhood Hits	581	Shared Neighborhood Hits	77
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KIF11_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.062328 (rank : 910)
Query Neighborhood Hits	326	Target Neighborhood Hits	583	Shared Neighborhood Hits	81
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

KIF14_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.066260 (rank : 825)
Query Neighborhood Hits	326	Target Neighborhood Hits	732	Shared Neighborhood Hits	121
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

KIF23_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.079321 (rank : 587)
Query Neighborhood Hits	326	Target Neighborhood Hits	618	Shared Neighborhood Hits	116
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

KIF3A_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.057753 (rank : 979)
Query Neighborhood Hits	326	Target Neighborhood Hits	704	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3A_MOUSE
θ value	θ > 10 (rank : 727)	NC score	0.063397 (rank : 888)
Query Neighborhood Hits	326	Target Neighborhood Hits	715	Shared Neighborhood Hits	114
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF5C_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.072833 (rank : 682)
Query Neighborhood Hits	326	Target Neighborhood Hits	974	Shared Neighborhood Hits	115
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_MOUSE
θ value	θ > 10 (rank : 729)	NC score	0.087033 (rank : 516)
Query Neighborhood Hits	326	Target Neighborhood Hits	1040	Shared Neighborhood Hits	139
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIFC3_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.054123 (rank : 1071)
Query Neighborhood Hits	326	Target Neighborhood Hits	619	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIFC3_MOUSE
θ value	θ > 10 (rank : 731)	NC score	0.054597 (rank : 1060)
Query Neighborhood Hits	326	Target Neighborhood Hits	571	Shared Neighborhood Hits	81
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KINH_MOUSE
θ value	θ > 10 (rank : 732)	NC score	0.093727 (rank : 446)
Query Neighborhood Hits	326	Target Neighborhood Hits	1082	Shared Neighborhood Hits	153
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KIT_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.071254 (rank : 717)
Query Neighborhood Hits	326	Target Neighborhood Hits	953	Shared Neighborhood Hits	41
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 734)	NC score	0.071280 (rank : 715)
Query Neighborhood Hits	326	Target Neighborhood Hits	949	Shared Neighborhood Hits	41
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KMHN1_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.116850 (rank : 253)
Query Neighborhood Hits	326	Target Neighborhood Hits	950	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KMHN1_MOUSE
θ value	θ > 10 (rank : 736)	NC score	0.111015 (rank : 302)
Query Neighborhood Hits	326	Target Neighborhood Hits	949	Shared Neighborhood Hits	135
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

KNTC2_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.079398 (rank : 586)
Query Neighborhood Hits	326	Target Neighborhood Hits	673	Shared Neighborhood Hits	85
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KNTC2_MOUSE
θ value	θ > 10 (rank : 738)	NC score	0.088128 (rank : 503)
Query Neighborhood Hits	326	Target Neighborhood Hits	692	Shared Neighborhood Hits	90
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

KSR1_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.055233 (rank : 1055)
Query Neighborhood Hits	326	Target Neighborhood Hits	867	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

KSR1_MOUSE
θ value	θ > 10 (rank : 740)	NC score	0.054401 (rank : 1068)
Query Neighborhood Hits	326	Target Neighborhood Hits	870	Shared Neighborhood Hits	43
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

KSR2_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.055442 (rank : 1051)
Query Neighborhood Hits	326	Target Neighborhood Hits	920	Shared Neighborhood Hits	42
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

KTN1_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.092108 (rank : 459)
Query Neighborhood Hits	326	Target Neighborhood Hits	1197	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KTN1_MOUSE
θ value	θ > 10 (rank : 743)	NC score	0.116673 (rank : 254)
Query Neighborhood Hits	326	Target Neighborhood Hits	1324	Shared Neighborhood Hits	155
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LAD1_MOUSE
θ value	θ > 10 (rank : 744)	NC score	0.060854 (rank : 936)
Query Neighborhood Hits	326	Target Neighborhood Hits	391	Shared Neighborhood Hits	65
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LBN_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.061333 (rank : 922)
Query Neighborhood Hits	326	Target Neighborhood Hits	308	Shared Neighborhood Hits	59
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

LBN_MOUSE
θ value	θ > 10 (rank : 746)	NC score	0.057088 (rank : 1002)
Query Neighborhood Hits	326	Target Neighborhood Hits	310	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

LC7L2_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.056328 (rank : 1022)
Query Neighborhood Hits	326	Target Neighborhood Hits	235	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

LC7L2_MOUSE
θ value	θ > 10 (rank : 748)	NC score	0.056228 (rank : 1028)
Query Neighborhood Hits	326	Target Neighborhood Hits	244	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

LCP2_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.090116 (rank : 479)
Query Neighborhood Hits	326	Target Neighborhood Hits	531	Shared Neighborhood Hits	67
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LCP2_MOUSE
θ value	θ > 10 (rank : 750)	NC score	0.109995 (rank : 309)
Query Neighborhood Hits	326	Target Neighborhood Hits	177	Shared Neighborhood Hits	50
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LIMK1_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.051193 (rank : 1138)
Query Neighborhood Hits	326	Target Neighborhood Hits	1005	Shared Neighborhood Hits	43
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK1_MOUSE
θ value	θ > 10 (rank : 752)	NC score	0.051151 (rank : 1139)
Query Neighborhood Hits	326	Target Neighborhood Hits	1008	Shared Neighborhood Hits	43
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

LIMK2_MOUSE
θ value	θ > 10 (rank : 753)	NC score	0.050404 (rank : 1158)
Query Neighborhood Hits	326	Target Neighborhood Hits	998	Shared Neighborhood Hits	44
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LIPA1_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.118980 (rank : 230)
Query Neighborhood Hits	326	Target Neighborhood Hits	1294	Shared Neighborhood Hits	169
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LIPA2_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.094939 (rank : 431)
Query Neighborhood Hits	326	Target Neighborhood Hits	1044	Shared Neighborhood Hits	132
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.109451 (rank : 317)
Query Neighborhood Hits	326	Target Neighborhood Hits	1282	Shared Neighborhood Hits	155
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA3_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.068960 (rank : 761)
Query Neighborhood Hits	326	Target Neighborhood Hits	828	Shared Neighborhood Hits	96
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPA3_MOUSE
θ value	θ > 10 (rank : 758)	NC score	0.056187 (rank : 1029)
Query Neighborhood Hits	326	Target Neighborhood Hits	636	Shared Neighborhood Hits	82
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPB1_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.060897 (rank : 935)
Query Neighborhood Hits	326	Target Neighborhood Hits	640	Shared Neighborhood Hits	80
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

LIPB1_MOUSE
θ value	θ > 10 (rank : 760)	NC score	0.075938 (rank : 642)
Query Neighborhood Hits	326	Target Neighborhood Hits	727	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

LIPB2_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.050329 (rank : 1161)
Query Neighborhood Hits	326	Target Neighborhood Hits	599	Shared Neighborhood Hits	77
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LMNA_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.058581 (rank : 969)
Query Neighborhood Hits	326	Target Neighborhood Hits	653	Shared Neighborhood Hits	96
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LMNA_MOUSE
θ value	θ > 10 (rank : 763)	NC score	0.058691 (rank : 966)
Query Neighborhood Hits	326	Target Neighborhood Hits	661	Shared Neighborhood Hits	100
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

LMNB1_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.069216 (rank : 752)
Query Neighborhood Hits	326	Target Neighborhood Hits	714	Shared Neighborhood Hits	106
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

LMNB1_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.067287 (rank : 800)
Query Neighborhood Hits	326	Target Neighborhood Hits	719	Shared Neighborhood Hits	106
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

LMNB2_MOUSE
θ value	θ > 10 (rank : 766)	NC score	0.063208 (rank : 892)
Query Neighborhood Hits	326	Target Neighborhood Hits	674	Shared Neighborhood Hits	94
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

LMO7_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.059433 (rank : 957)
Query Neighborhood Hits	326	Target Neighborhood Hits	507	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LRC27_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.087822 (rank : 508)
Query Neighborhood Hits	326	Target Neighborhood Hits	710	Shared Neighborhood Hits	111
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

LRC45_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.096036 (rank : 418)
Query Neighborhood Hits	326	Target Neighborhood Hits	933	Shared Neighborhood Hits	120
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.109497 (rank : 316)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRF1_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.086262 (rank : 527)
Query Neighborhood Hits	326	Target Neighborhood Hits	625	Shared Neighborhood Hits	104
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

LRRF1_MOUSE
θ value	θ > 10 (rank : 772)	NC score	0.052886 (rank : 1094)
Query Neighborhood Hits	326	Target Neighborhood Hits	440	Shared Neighborhood Hits	71
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

LRRF2_HUMAN
θ value	θ > 10 (rank : 773)	NC score	0.102952 (rank : 369)
Query Neighborhood Hits	326	Target Neighborhood Hits	791	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LRRF2_MOUSE
θ value	θ > 10 (rank : 774)	NC score	0.094104 (rank : 441)
Query Neighborhood Hits	326	Target Neighborhood Hits	556	Shared Neighborhood Hits	92
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LRSM1_HUMAN
θ value	θ > 10 (rank : 775)	NC score	0.067338 (rank : 796)
Query Neighborhood Hits	326	Target Neighborhood Hits	1078	Shared Neighborhood Hits	112
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LRSM1_MOUSE
θ value	θ > 10 (rank : 776)	NC score	0.059168 (rank : 959)
Query Neighborhood Hits	326	Target Neighborhood Hits	874	Shared Neighborhood Hits	90
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

LTK_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.077625 (rank : 617)
Query Neighborhood Hits	326	Target Neighborhood Hits	774	Shared Neighborhood Hits	41
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.076397 (rank : 635)
Query Neighborhood Hits	326	Target Neighborhood Hits	770	Shared Neighborhood Hits	41
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LUZP1_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.079288 (rank : 590)
Query Neighborhood Hits	326	Target Neighborhood Hits	739	Shared Neighborhood Hits	95
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LUZP1_MOUSE
θ value	θ > 10 (rank : 780)	NC score	0.102659 (rank : 372)
Query Neighborhood Hits	326	Target Neighborhood Hits	940	Shared Neighborhood Hits	141
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

LZTS1_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.060513 (rank : 944)
Query Neighborhood Hits	326	Target Neighborhood Hits	532	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LZTS1_MOUSE
θ value	θ > 10 (rank : 782)	NC score	0.068289 (rank : 777)
Query Neighborhood Hits	326	Target Neighborhood Hits	540	Shared Neighborhood Hits	72
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LZTS2_HUMAN
θ value	θ > 10 (rank : 783)	NC score	0.052529 (rank : 1101)
Query Neighborhood Hits	326	Target Neighborhood Hits	427	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

M3K10_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.066689 (rank : 813)
Query Neighborhood Hits	326	Target Neighborhood Hits	1071	Shared Neighborhood Hits	77
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

M3K11_HUMAN
θ value	θ > 10 (rank : 785)	NC score	0.068690 (rank : 768)
Query Neighborhood Hits	326	Target Neighborhood Hits	1136	Shared Neighborhood Hits	71
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

M3K12_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.055176 (rank : 1056)
Query Neighborhood Hits	326	Target Neighborhood Hits	940	Shared Neighborhood Hits	45
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	θ > 10 (rank : 787)	NC score	0.055510 (rank : 1049)
Query Neighborhood Hits	326	Target Neighborhood Hits	957	Shared Neighborhood Hits	48
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K13_HUMAN
θ value	θ > 10 (rank : 788)	NC score	0.055437 (rank : 1052)
Query Neighborhood Hits	326	Target Neighborhood Hits	911	Shared Neighborhood Hits	44
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M3K7_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.053886 (rank : 1074)
Query Neighborhood Hits	326	Target Neighborhood Hits	892	Shared Neighborhood Hits	54
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_MOUSE
θ value	θ > 10 (rank : 790)	NC score	0.053901 (rank : 1072)
Query Neighborhood Hits	326	Target Neighborhood Hits	892	Shared Neighborhood Hits	54
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K9_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.067755 (rank : 788)
Query Neighborhood Hits	326	Target Neighborhood Hits	1123	Shared Neighborhood Hits	77
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M3KL4_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.071550 (rank : 710)
Query Neighborhood Hits	326	Target Neighborhood Hits	1087	Shared Neighborhood Hits	80
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

M4K4_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.054502 (rank : 1063)
Query Neighborhood Hits	326	Target Neighborhood Hits	1589	Shared Neighborhood Hits	128
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	θ > 10 (rank : 794)	NC score	0.056555 (rank : 1018)
Query Neighborhood Hits	326	Target Neighborhood Hits	1560	Shared Neighborhood Hits	131
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MACF1_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.074652 (rank : 654)
Query Neighborhood Hits	326	Target Neighborhood Hits	1341	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF1_MOUSE
θ value	θ > 10 (rank : 796)	NC score	0.074803 (rank : 651)
Query Neighborhood Hits	326	Target Neighborhood Hits	1313	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MACF4_HUMAN
θ value	θ > 10 (rank : 797)	NC score	0.077586 (rank : 618)
Query Neighborhood Hits	326	Target Neighborhood Hits	1321	Shared Neighborhood Hits	121
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MD1L1_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.100793 (rank : 384)
Query Neighborhood Hits	326	Target Neighborhood Hits	893	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 799)	NC score	0.106427 (rank : 338)
Query Neighborhood Hits	326	Target Neighborhood Hits	1001	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MDC1_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.062331 (rank : 909)
Query Neighborhood Hits	326	Target Neighborhood Hits	1446	Shared Neighborhood Hits	116
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDN1_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.067246 (rank : 801)
Query Neighborhood Hits	326	Target Neighborhood Hits	662	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MERL_HUMAN
θ value	θ > 10 (rank : 802)	NC score	0.064367 (rank : 867)
Query Neighborhood Hits	326	Target Neighborhood Hits	532	Shared Neighborhood Hits	87
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	θ > 10 (rank : 803)	NC score	0.066675 (rank : 814)
Query Neighborhood Hits	326	Target Neighborhood Hits	524	Shared Neighborhood Hits	88
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERTK_HUMAN
θ value	θ > 10 (rank : 804)	NC score	0.072856 (rank : 679)
Query Neighborhood Hits	326	Target Neighborhood Hits	988	Shared Neighborhood Hits	41
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	θ > 10 (rank : 805)	NC score	0.072244 (rank : 691)
Query Neighborhood Hits	326	Target Neighborhood Hits	974	Shared Neighborhood Hits	43
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MET_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.068821 (rank : 766)
Query Neighborhood Hits	326	Target Neighborhood Hits	831	Shared Neighborhood Hits	41
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 807)	NC score	0.068956 (rank : 762)
Query Neighborhood Hits	326	Target Neighborhood Hits	844	Shared Neighborhood Hits	41
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MINK1_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.051348 (rank : 1132)
Query Neighborhood Hits	326	Target Neighborhood Hits	1477	Shared Neighborhood Hits	114
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	θ > 10 (rank : 809)	NC score	0.050927 (rank : 1146)
Query Neighborhood Hits	326	Target Neighborhood Hits	1451	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINT_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.091960 (rank : 463)
Query Neighborhood Hits	326	Target Neighborhood Hits	1291	Shared Neighborhood Hits	130
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MINT_MOUSE
θ value	θ > 10 (rank : 811)	NC score	0.076803 (rank : 630)
Query Neighborhood Hits	326	Target Neighborhood Hits	1514	Shared Neighborhood Hits	114
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MIPO1_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.079245 (rank : 591)
Query Neighborhood Hits	326	Target Neighborhood Hits	486	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

MLKL_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.067098 (rank : 802)
Query Neighborhood Hits	326	Target Neighborhood Hits	600	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 814)	NC score	0.067288 (rank : 799)
Query Neighborhood Hits	326	Target Neighborhood Hits	707	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLTK_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.057867 (rank : 978)
Query Neighborhood Hits	326	Target Neighborhood Hits	911	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
θ value	θ > 10 (rank : 816)	NC score	0.058064 (rank : 975)
Query Neighborhood Hits	326	Target Neighborhood Hits	874	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MMRN1_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.063601 (rank : 880)
Query Neighborhood Hits	326	Target Neighborhood Hits	636	Shared Neighborhood Hits	65
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MMRN2_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.054810 (rank : 1059)
Query Neighborhood Hits	326	Target Neighborhood Hits	400	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

MOES_HUMAN
θ value	θ > 10 (rank : 819)	NC score	0.082490 (rank : 559)
Query Neighborhood Hits	326	Target Neighborhood Hits	892	Shared Neighborhood Hits	110
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MORC3_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.058780 (rank : 964)
Query Neighborhood Hits	326	Target Neighborhood Hits	489	Shared Neighborhood Hits	83
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

MOS_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.056682 (rank : 1015)
Query Neighborhood Hits	326	Target Neighborhood Hits	829	Shared Neighborhood Hits	41
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MOS_MOUSE
θ value	θ > 10 (rank : 822)	NC score	0.055536 (rank : 1046)
Query Neighborhood Hits	326	Target Neighborhood Hits	833	Shared Neighborhood Hits	42
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MPP10_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.057429 (rank : 986)
Query Neighborhood Hits	326	Target Neighborhood Hits	306	Shared Neighborhood Hits	61
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MPP10_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.056554 (rank : 1019)
Query Neighborhood Hits	326	Target Neighborhood Hits	251	Shared Neighborhood Hits	57
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MPP9_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.077748 (rank : 614)
Query Neighborhood Hits	326	Target Neighborhood Hits	529	Shared Neighborhood Hits	76
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

MRCKA_HUMAN
θ value	θ > 10 (rank : 826)	NC score	0.072321 (rank : 690)
Query Neighborhood Hits	326	Target Neighborhood Hits	1999	Shared Neighborhood Hits	179
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MRCKB_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.086274 (rank : 526)
Query Neighborhood Hits	326	Target Neighborhood Hits	2239	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.086226 (rank : 529)
Query Neighborhood Hits	326	Target Neighborhood Hits	2180	Shared Neighborhood Hits	201
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRIP_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.064657 (rank : 861)
Query Neighborhood Hits	326	Target Neighborhood Hits	578	Shared Neighborhood Hits	77
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.066830 (rank : 807)
Query Neighborhood Hits	326	Target Neighborhood Hits	569	Shared Neighborhood Hits	78
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MUSK_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.066023 (rank : 833)
Query Neighborhood Hits	326	Target Neighborhood Hits	1074	Shared Neighborhood Hits	41
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 832)	NC score	0.066330 (rank : 821)
Query Neighborhood Hits	326	Target Neighborhood Hits	1057	Shared Neighborhood Hits	41
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MY18B_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.098370 (rank : 398)
Query Neighborhood Hits	326	Target Neighborhood Hits	1299	Shared Neighborhood Hits	132
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH14_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.081944 (rank : 566)
Query Neighborhood Hits	326	Target Neighborhood Hits	995	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 835)	NC score	0.097534 (rank : 406)
Query Neighborhood Hits	326	Target Neighborhood Hits	1225	Shared Neighborhood Hits	123
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH1_HUMAN
θ value	θ > 10 (rank : 836)	NC score	0.092638 (rank : 452)
Query Neighborhood Hits	326	Target Neighborhood Hits	1478	Shared Neighborhood Hits	150
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	θ > 10 (rank : 837)	NC score	0.094260 (rank : 437)
Query Neighborhood Hits	326	Target Neighborhood Hits	1461	Shared Neighborhood Hits	144
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.093971 (rank : 445)
Query Neighborhood Hits	326	Target Neighborhood Hits	1491	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH3_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.103926 (rank : 362)
Query Neighborhood Hits	326	Target Neighborhood Hits	1660	Shared Neighborhood Hits	165
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH4_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.087823 (rank : 507)
Query Neighborhood Hits	326	Target Neighborhood Hits	1377	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH4_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.091570 (rank : 466)
Query Neighborhood Hits	326	Target Neighborhood Hits	1476	Shared Neighborhood Hits	143
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.096342 (rank : 416)
Query Neighborhood Hits	326	Target Neighborhood Hits	1426	Shared Neighborhood Hits	142
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.095324 (rank : 424)
Query Neighborhood Hits	326	Target Neighborhood Hits	1501	Shared Neighborhood Hits	146
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.094719 (rank : 434)
Query Neighborhood Hits	326	Target Neighborhood Hits	1559	Shared Neighborhood Hits	158
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH8_HUMAN
θ value	θ > 10 (rank : 845)	NC score	0.100838 (rank : 382)
Query Neighborhood Hits	326	Target Neighborhood Hits	1610	Shared Neighborhood Hits	168
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	θ > 10 (rank : 846)	NC score	0.097974 (rank : 399)
Query Neighborhood Hits	326	Target Neighborhood Hits	1600	Shared Neighborhood Hits	159
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYO10_HUMAN
θ value	θ > 10 (rank : 847)	NC score	0.072361 (rank : 688)
Query Neighborhood Hits	326	Target Neighborhood Hits	920	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO1E_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.058264 (rank : 973)
Query Neighborhood Hits	326	Target Neighborhood Hits	293	Shared Neighborhood Hits	46
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYO1F_HUMAN
θ value	θ > 10 (rank : 849)	NC score	0.056540 (rank : 1020)
Query Neighborhood Hits	326	Target Neighborhood Hits	275	Shared Neighborhood Hits	46
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 850)	NC score	0.056760 (rank : 1012)
Query Neighborhood Hits	326	Target Neighborhood Hits	262	Shared Neighborhood Hits	46
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

MYO3A_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.056557 (rank : 1017)
Query Neighborhood Hits	326	Target Neighborhood Hits	1033	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

MYO5A_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.092012 (rank : 461)
Query Neighborhood Hits	326	Target Neighborhood Hits	1092	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	θ > 10 (rank : 853)	NC score	0.091730 (rank : 464)
Query Neighborhood Hits	326	Target Neighborhood Hits	1117	Shared Neighborhood Hits	151
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5B_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.077907 (rank : 610)
Query Neighborhood Hits	326	Target Neighborhood Hits	911	Shared Neighborhood Hits	131
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO5C_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.094007 (rank : 444)
Query Neighborhood Hits	326	Target Neighborhood Hits	1206	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYO6_MOUSE
θ value	θ > 10 (rank : 856)	NC score	0.069560 (rank : 747)
Query Neighborhood Hits	326	Target Neighborhood Hits	586	Shared Neighborhood Hits	88
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

NAF1_MOUSE
θ value	θ > 10 (rank : 857)	NC score	0.105123 (rank : 349)
Query Neighborhood Hits	326	Target Neighborhood Hits	852	Shared Neighborhood Hits	119
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NALP5_MOUSE
θ value	θ > 10 (rank : 858)	NC score	0.052058 (rank : 1112)
Query Neighborhood Hits	326	Target Neighborhood Hits	560	Shared Neighborhood Hits	107
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NASP_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.110709 (rank : 304)
Query Neighborhood Hits	326	Target Neighborhood Hits	709	Shared Neighborhood Hits	115
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NBN_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.052469 (rank : 1103)
Query Neighborhood Hits	326	Target Neighborhood Hits	226	Shared Neighborhood Hits	59
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

NCF1_HUMAN
θ value	θ > 10 (rank : 861)	NC score	0.057031 (rank : 1005)
Query Neighborhood Hits	326	Target Neighborhood Hits	198	Shared Neighborhood Hits	33
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	θ > 10 (rank : 862)	NC score	0.057350 (rank : 991)
Query Neighborhood Hits	326	Target Neighborhood Hits	198	Shared Neighborhood Hits	34
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCF2_HUMAN
θ value	θ > 10 (rank : 863)	NC score	0.051578 (rank : 1127)
Query Neighborhood Hits	326	Target Neighborhood Hits	229	Shared Neighborhood Hits	36
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCK1_HUMAN
θ value	θ > 10 (rank : 864)	NC score	0.270952 (rank : 37)
Query Neighborhood Hits	326	Target Neighborhood Hits	312	Shared Neighborhood Hits	87
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 865)	NC score	0.273496 (rank : 36)
Query Neighborhood Hits	326	Target Neighborhood Hits	310	Shared Neighborhood Hits	92
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NDEL1_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.075316 (rank : 646)
Query Neighborhood Hits	326	Target Neighborhood Hits	415	Shared Neighborhood Hits	65
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

NDEL1_MOUSE
θ value	θ > 10 (rank : 867)	NC score	0.075032 (rank : 648)
Query Neighborhood Hits	326	Target Neighborhood Hits	420	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

NEB1_HUMAN
θ value	θ > 10 (rank : 868)	NC score	0.073455 (rank : 669)
Query Neighborhood Hits	326	Target Neighborhood Hits	829	Shared Neighborhood Hits	110
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEB2_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.077483 (rank : 622)
Query Neighborhood Hits	326	Target Neighborhood Hits	883	Shared Neighborhood Hits	114
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.079494 (rank : 584)
Query Neighborhood Hits	326	Target Neighborhood Hits	889	Shared Neighborhood Hits	115
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEBL_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.118431 (rank : 237)
Query Neighborhood Hits	326	Target Neighborhood Hits	457	Shared Neighborhood Hits	117
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	θ > 10 (rank : 872)	NC score	0.059777 (rank : 955)
Query Neighborhood Hits	326	Target Neighborhood Hits	420	Shared Neighborhood Hits	84
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NEK1_MOUSE
θ value	θ > 10 (rank : 873)	NC score	0.050941 (rank : 1145)
Query Neighborhood Hits	326	Target Neighborhood Hits	1311	Shared Neighborhood Hits	135
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

NEMO_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.101004 (rank : 381)
Query Neighborhood Hits	326	Target Neighborhood Hits	820	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEMO_MOUSE
θ value	θ > 10 (rank : 875)	NC score	0.091588 (rank : 465)
Query Neighborhood Hits	326	Target Neighborhood Hits	658	Shared Neighborhood Hits	95
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NFM_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.075837 (rank : 643)
Query Neighborhood Hits	326	Target Neighborhood Hits	1328	Shared Neighborhood Hits	143
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NIN_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.109121 (rank : 320)
Query Neighborhood Hits	326	Target Neighborhood Hits	1416	Shared Neighborhood Hits	137
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NIN_MOUSE
θ value	θ > 10 (rank : 878)	NC score	0.109890 (rank : 311)
Query Neighborhood Hits	326	Target Neighborhood Hits	1376	Shared Neighborhood Hits	137
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NKTR_HUMAN
θ value	θ > 10 (rank : 879)	NC score	0.062937 (rank : 897)
Query Neighborhood Hits	326	Target Neighborhood Hits	658	Shared Neighborhood Hits	101
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NOL10_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.054496 (rank : 1064)
Query Neighborhood Hits	326	Target Neighborhood Hits	254	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NOP14_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.145366 (rank : 106)
Query Neighborhood Hits	326	Target Neighborhood Hits	573	Shared Neighborhood Hits	136
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NPBL_MOUSE
θ value	θ > 10 (rank : 882)	NC score	0.127253 (rank : 179)
Query Neighborhood Hits	326	Target Neighborhood Hits	1041	Shared Neighborhood Hits	132
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NPHP1_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.088505 (rank : 497)
Query Neighborhood Hits	326	Target Neighborhood Hits	288	Shared Neighborhood Hits	65
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP1_MOUSE
θ value	θ > 10 (rank : 884)	NC score	0.083546 (rank : 547)
Query Neighborhood Hits	326	Target Neighborhood Hits	267	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NSBP1_HUMAN
θ value	θ > 10 (rank : 885)	NC score	0.064306 (rank : 868)
Query Neighborhood Hits	326	Target Neighborhood Hits	251	Shared Neighborhood Hits	42
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NSBP1_MOUSE
θ value	θ > 10 (rank : 886)	NC score	0.072839 (rank : 681)
Query Neighborhood Hits	326	Target Neighborhood Hits	681	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NTBP1_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.096082 (rank : 417)
Query Neighborhood Hits	326	Target Neighborhood Hits	528	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

NTRK1_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.071169 (rank : 719)
Query Neighborhood Hits	326	Target Neighborhood Hits	1023	Shared Neighborhood Hits	41
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 889)	NC score	0.066236 (rank : 827)
Query Neighborhood Hits	326	Target Neighborhood Hits	1081	Shared Neighborhood Hits	41
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 890)	NC score	0.066240 (rank : 826)
Query Neighborhood Hits	326	Target Neighborhood Hits	1088	Shared Neighborhood Hits	41
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 891)	NC score	0.068038 (rank : 783)
Query Neighborhood Hits	326	Target Neighborhood Hits	1115	Shared Neighborhood Hits	41
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

NUCB1_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.057294 (rank : 994)
Query Neighborhood Hits	326	Target Neighborhood Hits	359	Shared Neighborhood Hits	83
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

NUCB1_MOUSE
θ value	θ > 10 (rank : 893)	NC score	0.059346 (rank : 958)
Query Neighborhood Hits	326	Target Neighborhood Hits	414	Shared Neighborhood Hits	81
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

NUCB2_MOUSE
θ value	θ > 10 (rank : 894)	NC score	0.050671 (rank : 1151)
Query Neighborhood Hits	326	Target Neighborhood Hits	459	Shared Neighborhood Hits	77
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

NUF2_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.090525 (rank : 475)
Query Neighborhood Hits	326	Target Neighborhood Hits	661	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

NUF2_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.082372 (rank : 562)
Query Neighborhood Hits	326	Target Neighborhood Hits	585	Shared Neighborhood Hits	92
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

NUMA1_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.110587 (rank : 305)
Query Neighborhood Hits	326	Target Neighborhood Hits	1523	Shared Neighborhood Hits	149
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

NUP88_HUMAN
θ value	θ > 10 (rank : 898)	NC score	0.062517 (rank : 907)
Query Neighborhood Hits	326	Target Neighborhood Hits	354	Shared Neighborhood Hits	77
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

NUP88_MOUSE
θ value	θ > 10 (rank : 899)	NC score	0.058348 (rank : 972)
Query Neighborhood Hits	326	Target Neighborhood Hits	239	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

OFD1_HUMAN
θ value	θ > 10 (rank : 900)	NC score	0.095837 (rank : 419)
Query Neighborhood Hits	326	Target Neighborhood Hits	753	Shared Neighborhood Hits	108
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

OPTN_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.112676 (rank : 286)
Query Neighborhood Hits	326	Target Neighborhood Hits	827	Shared Neighborhood Hits	137
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
θ value	θ > 10 (rank : 902)	NC score	0.122477 (rank : 209)
Query Neighborhood Hits	326	Target Neighborhood Hits	1120	Shared Neighborhood Hits	150
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

OSTF1_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.059843 (rank : 953)
Query Neighborhood Hits	326	Target Neighborhood Hits	466	Shared Neighborhood Hits	42
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	θ > 10 (rank : 904)	NC score	0.057652 (rank : 981)
Query Neighborhood Hits	326	Target Neighborhood Hits	467	Shared Neighborhood Hits	42
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

OXR1_MOUSE
θ value	θ > 10 (rank : 905)	NC score	0.073111 (rank : 677)
Query Neighborhood Hits	326	Target Neighborhood Hits	516	Shared Neighborhood Hits	83
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PACN1_HUMAN
θ value	θ > 10 (rank : 906)	NC score	0.063862 (rank : 876)
Query Neighborhood Hits	326	Target Neighborhood Hits	320	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	θ > 10 (rank : 907)	NC score	0.069183 (rank : 755)
Query Neighborhood Hits	326	Target Neighborhood Hits	283	Shared Neighborhood Hits	56
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN2_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.069126 (rank : 758)
Query Neighborhood Hits	326	Target Neighborhood Hits	339	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	θ > 10 (rank : 909)	NC score	0.072134 (rank : 695)
Query Neighborhood Hits	326	Target Neighborhood Hits	382	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.078673 (rank : 602)
Query Neighborhood Hits	326	Target Neighborhood Hits	385	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.074026 (rank : 660)
Query Neighborhood Hits	326	Target Neighborhood Hits	380	Shared Neighborhood Hits	84
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PCNT_MOUSE
θ value	θ > 10 (rank : 912)	NC score	0.110166 (rank : 307)
Query Neighborhood Hits	326	Target Neighborhood Hits	1207	Shared Neighborhood Hits	127
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PGFRA_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.069804 (rank : 740)
Query Neighborhood Hits	326	Target Neighborhood Hits	980	Shared Neighborhood Hits	44
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
θ value	θ > 10 (rank : 914)	NC score	0.069772 (rank : 742)
Query Neighborhood Hits	326	Target Neighborhood Hits	975	Shared Neighborhood Hits	41
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_HUMAN
θ value	θ > 10 (rank : 915)	NC score	0.069610 (rank : 745)
Query Neighborhood Hits	326	Target Neighborhood Hits	962	Shared Neighborhood Hits	41
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
θ value	θ > 10 (rank : 916)	NC score	0.069799 (rank : 741)
Query Neighborhood Hits	326	Target Neighborhood Hits	960	Shared Neighborhood Hits	42
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PHF20_HUMAN
θ value	θ > 10 (rank : 917)	NC score	0.085358 (rank : 538)
Query Neighborhood Hits	326	Target Neighborhood Hits	394	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 918)	NC score	0.104259 (rank : 358)
Query Neighborhood Hits	326	Target Neighborhood Hits	513	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF3_HUMAN
θ value	θ > 10 (rank : 919)	NC score	0.055942 (rank : 1037)
Query Neighborhood Hits	326	Target Neighborhood Hits	419	Shared Neighborhood Hits	68
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PHLB1_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.082909 (rank : 555)
Query Neighborhood Hits	326	Target Neighborhood Hits	1038	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	θ > 10 (rank : 921)	NC score	0.053185 (rank : 1084)
Query Neighborhood Hits	326	Target Neighborhood Hits	678	Shared Neighborhood Hits	69
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB2_HUMAN
θ value	θ > 10 (rank : 922)	NC score	0.104368 (rank : 357)
Query Neighborhood Hits	326	Target Neighborhood Hits	964	Shared Neighborhood Hits	135
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
θ value	θ > 10 (rank : 923)	NC score	0.109751 (rank : 313)
Query Neighborhood Hits	326	Target Neighborhood Hits	1016	Shared Neighborhood Hits	142
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB3_HUMAN
θ value	θ > 10 (rank : 924)	NC score	0.050183 (rank : 1162)
Query Neighborhood Hits	326	Target Neighborhood Hits	304	Shared Neighborhood Hits	49
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

PIBF1_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.129208 (rank : 161)
Query Neighborhood Hits	326	Target Neighborhood Hits	1041	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PININ_HUMAN
θ value	θ > 10 (rank : 926)	NC score	0.110423 (rank : 306)
Query Neighborhood Hits	326	Target Neighborhood Hits	753	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	θ > 10 (rank : 927)	NC score	0.108180 (rank : 327)
Query Neighborhood Hits	326	Target Neighborhood Hits	777	Shared Neighborhood Hits	127
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PKHA5_HUMAN
θ value	θ > 10 (rank : 928)	NC score	0.053682 (rank : 1078)
Query Neighborhood Hits	326	Target Neighborhood Hits	455	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PLCB1_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.092543 (rank : 454)
Query Neighborhood Hits	326	Target Neighborhood Hits	614	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB1_MOUSE
θ value	θ > 10 (rank : 930)	NC score	0.086109 (rank : 531)
Query Neighborhood Hits	326	Target Neighborhood Hits	531	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB2_HUMAN
θ value	θ > 10 (rank : 931)	NC score	0.097171 (rank : 409)
Query Neighborhood Hits	326	Target Neighborhood Hits	608	Shared Neighborhood Hits	114
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

PLCB3_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.089691 (rank : 486)
Query Neighborhood Hits	326	Target Neighborhood Hits	445	Shared Neighborhood Hits	112
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLCB3_MOUSE
θ value	θ > 10 (rank : 933)	NC score	0.067985 (rank : 785)
Query Neighborhood Hits	326	Target Neighborhood Hits	344	Shared Neighborhood Hits	71
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLCB4_HUMAN
θ value	θ > 10 (rank : 934)	NC score	0.123649 (rank : 204)
Query Neighborhood Hits	326	Target Neighborhood Hits	658	Shared Neighborhood Hits	129
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

PLVAP_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.075535 (rank : 644)
Query Neighborhood Hits	326	Target Neighborhood Hits	397	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

POF1B_HUMAN
θ value	θ > 10 (rank : 936)	NC score	0.069212 (rank : 753)
Query Neighborhood Hits	326	Target Neighborhood Hits	494	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

POF1B_MOUSE
θ value	θ > 10 (rank : 937)	NC score	0.069806 (rank : 739)
Query Neighborhood Hits	326	Target Neighborhood Hits	530	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

POT15_HUMAN
θ value	θ > 10 (rank : 938)	NC score	0.057171 (rank : 1000)
Query Neighborhood Hits	326	Target Neighborhood Hits	893	Shared Neighborhood Hits	134
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

PPIP1_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.081651 (rank : 570)
Query Neighborhood Hits	326	Target Neighborhood Hits	389	Shared Neighborhood Hits	84
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PPIP1_MOUSE
θ value	θ > 10 (rank : 940)	NC score	0.081144 (rank : 575)
Query Neighborhood Hits	326	Target Neighborhood Hits	377	Shared Neighborhood Hits	85
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PPIP2_MOUSE
θ value	θ > 10 (rank : 941)	NC score	0.056251 (rank : 1027)
Query Neighborhood Hits	326	Target Neighborhood Hits	308	Shared Neighborhood Hits	79
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PRC1_HUMAN
θ value	θ > 10 (rank : 942)	NC score	0.073372 (rank : 671)
Query Neighborhood Hits	326	Target Neighborhood Hits	328	Shared Neighborhood Hits	69
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

PRC1_MOUSE
θ value	θ > 10 (rank : 943)	NC score	0.076573 (rank : 632)
Query Neighborhood Hits	326	Target Neighborhood Hits	382	Shared Neighborhood Hits	83
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

PTK7_HUMAN
θ value	θ > 10 (rank : 944)	NC score	0.063450 (rank : 883)
Query Neighborhood Hits	326	Target Neighborhood Hits	1103	Shared Neighborhood Hits	41
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

PTN6_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.161228 (rank : 80)
Query Neighborhood Hits	326	Target Neighborhood Hits	234	Shared Neighborhood Hits	90
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

RAB3I_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.055645 (rank : 1042)
Query Neighborhood Hits	326	Target Neighborhood Hits	270	Shared Neighborhood Hits	61
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

RABE2_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.091175 (rank : 469)
Query Neighborhood Hits	326	Target Neighborhood Hits	545	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RABE2_MOUSE
θ value	θ > 10 (rank : 948)	NC score	0.092581 (rank : 453)
Query Neighborhood Hits	326	Target Neighborhood Hits	598	Shared Neighborhood Hits	98
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RAD50_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.124648 (rank : 195)
Query Neighborhood Hits	326	Target Neighborhood Hits	1317	Shared Neighborhood Hits	150
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 950)	NC score	0.127057 (rank : 181)
Query Neighborhood Hits	326	Target Neighborhood Hits	1366	Shared Neighborhood Hits	156
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RAF1_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.057108 (rank : 1001)
Query Neighborhood Hits	326	Target Neighborhood Hits	886	Shared Neighborhood Hits	46
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	θ > 10 (rank : 952)	NC score	0.056873 (rank : 1009)
Query Neighborhood Hits	326	Target Neighborhood Hits	886	Shared Neighborhood Hits	46
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAI14_HUMAN
θ value	θ > 10 (rank : 953)	NC score	0.066803 (rank : 809)
Query Neighborhood Hits	326	Target Neighborhood Hits	1367	Shared Neighborhood Hits	121
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RAI14_MOUSE
θ value	θ > 10 (rank : 954)	NC score	0.090534 (rank : 474)
Query Neighborhood Hits	326	Target Neighborhood Hits	1505	Shared Neighborhood Hits	157
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RASF8_HUMAN
θ value	θ > 10 (rank : 955)	NC score	0.069715 (rank : 744)
Query Neighborhood Hits	326	Target Neighborhood Hits	469	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

RASF8_MOUSE
θ value	θ > 10 (rank : 956)	NC score	0.059131 (rank : 961)
Query Neighborhood Hits	326	Target Neighborhood Hits	391	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

RB6I2_HUMAN
θ value	θ > 10 (rank : 957)	NC score	0.132346 (rank : 148)
Query Neighborhood Hits	326	Target Neighborhood Hits	1584	Shared Neighborhood Hits	174
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	θ > 10 (rank : 958)	NC score	0.126966 (rank : 182)
Query Neighborhood Hits	326	Target Neighborhood Hits	1433	Shared Neighborhood Hits	167
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBBP8_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.086521 (rank : 522)
Query Neighborhood Hits	326	Target Neighborhood Hits	476	Shared Neighborhood Hits	95
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

RBCC1_HUMAN
θ value	θ > 10 (rank : 960)	NC score	0.093626 (rank : 447)
Query Neighborhood Hits	326	Target Neighborhood Hits	1023	Shared Neighborhood Hits	123
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBCC1_MOUSE
θ value	θ > 10 (rank : 961)	NC score	0.100003 (rank : 390)
Query Neighborhood Hits	326	Target Neighborhood Hits	1048	Shared Neighborhood Hits	127
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RBP24_HUMAN
θ value	θ > 10 (rank : 962)	NC score	0.112940 (rank : 282)
Query Neighborhood Hits	326	Target Neighborhood Hits	1559	Shared Neighborhood Hits	146
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

REN3A_HUMAN
θ value	θ > 10 (rank : 963)	NC score	0.060554 (rank : 942)
Query Neighborhood Hits	326	Target Neighborhood Hits	248	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

REST_HUMAN
θ value	θ > 10 (rank : 964)	NC score	0.128119 (rank : 168)
Query Neighborhood Hits	326	Target Neighborhood Hits	1605	Shared Neighborhood Hits	173
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RET_HUMAN
θ value	θ > 10 (rank : 965)	NC score	0.070636 (rank : 728)
Query Neighborhood Hits	326	Target Neighborhood Hits	873	Shared Neighborhood Hits	41
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 966)	NC score	0.070279 (rank : 733)
Query Neighborhood Hits	326	Target Neighborhood Hits	884	Shared Neighborhood Hits	41
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RFC1_HUMAN
θ value	θ > 10 (rank : 967)	NC score	0.103156 (rank : 367)
Query Neighborhood Hits	326	Target Neighborhood Hits	352	Shared Neighborhood Hits	75
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFIP3_HUMAN
θ value	θ > 10 (rank : 968)	NC score	0.102241 (rank : 377)
Query Neighborhood Hits	326	Target Neighborhood Hits	1055	Shared Neighborhood Hits	132
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RFIP4_HUMAN
θ value	θ > 10 (rank : 969)	NC score	0.091189 (rank : 468)
Query Neighborhood Hits	326	Target Neighborhood Hits	785	Shared Neighborhood Hits	113
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RFIP4_MOUSE
θ value	θ > 10 (rank : 970)	NC score	0.079464 (rank : 585)
Query Neighborhood Hits	326	Target Neighborhood Hits	708	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RGNEF_MOUSE
θ value	θ > 10 (rank : 971)	NC score	0.065789 (rank : 837)
Query Neighborhood Hits	326	Target Neighborhood Hits	641	Shared Neighborhood Hits	105
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RHG25_HUMAN
θ value	θ > 10 (rank : 972)	NC score	0.056837 (rank : 1011)
Query Neighborhood Hits	326	Target Neighborhood Hits	550	Shared Neighborhood Hits	82
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RIMB1_MOUSE
θ value	θ > 10 (rank : 973)	NC score	0.127756 (rank : 171)
Query Neighborhood Hits	326	Target Neighborhood Hits	1376	Shared Neighborhood Hits	163
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIPK1_HUMAN
θ value	θ > 10 (rank : 974)	NC score	0.055965 (rank : 1035)
Query Neighborhood Hits	326	Target Neighborhood Hits	891	Shared Neighborhood Hits	44
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_MOUSE
θ value	θ > 10 (rank : 975)	NC score	0.057276 (rank : 996)
Query Neighborhood Hits	326	Target Neighborhood Hits	874	Shared Neighborhood Hits	46
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK2_HUMAN
θ value	θ > 10 (rank : 976)	NC score	0.051767 (rank : 1119)
Query Neighborhood Hits	326	Target Neighborhood Hits	774	Shared Neighborhood Hits	39
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	θ > 10 (rank : 977)	NC score	0.053756 (rank : 1077)
Query Neighborhood Hits	326	Target Neighborhood Hits	776	Shared Neighborhood Hits	39
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK3_HUMAN
θ value	θ > 10 (rank : 978)	NC score	0.051781 (rank : 1118)
Query Neighborhood Hits	326	Target Neighborhood Hits	828	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

RNF8_HUMAN
θ value	θ > 10 (rank : 979)	NC score	0.050819 (rank : 1149)
Query Neighborhood Hits	326	Target Neighborhood Hits	622	Shared Neighborhood Hits	65
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 980)	NC score	0.053619 (rank : 1079)
Query Neighborhood Hits	326	Target Neighborhood Hits	618	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

ROCK1_HUMAN
θ value	θ > 10 (rank : 981)	NC score	0.076200 (rank : 637)
Query Neighborhood Hits	326	Target Neighborhood Hits	2000	Shared Neighborhood Hits	177
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
θ value	θ > 10 (rank : 982)	NC score	0.085740 (rank : 534)
Query Neighborhood Hits	326	Target Neighborhood Hits	2126	Shared Neighborhood Hits	191
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

ROCK2_HUMAN
θ value	θ > 10 (rank : 983)	NC score	0.080926 (rank : 576)
Query Neighborhood Hits	326	Target Neighborhood Hits	2073	Shared Neighborhood Hits	195
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
θ value	θ > 10 (rank : 984)	NC score	0.081259 (rank : 573)
Query Neighborhood Hits	326	Target Neighborhood Hits	2072	Shared Neighborhood Hits	192
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RON_HUMAN
θ value	θ > 10 (rank : 985)	NC score	0.069519 (rank : 748)
Query Neighborhood Hits	326	Target Neighborhood Hits	842	Shared Neighborhood Hits	41
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 986)	NC score	0.071028 (rank : 720)
Query Neighborhood Hits	326	Target Neighborhood Hits	836	Shared Neighborhood Hits	41
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 987)	NC score	0.068500 (rank : 773)
Query Neighborhood Hits	326	Target Neighborhood Hits	1018	Shared Neighborhood Hits	43
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 988)	NC score	0.068560 (rank : 772)
Query Neighborhood Hits	326	Target Neighborhood Hits	1025	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 989)	NC score	0.069191 (rank : 754)
Query Neighborhood Hits	326	Target Neighborhood Hits	1014	Shared Neighborhood Hits	43
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 990)	NC score	0.070451 (rank : 730)
Query Neighborhood Hits	326	Target Neighborhood Hits	1000	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

ROS_HUMAN
θ value	θ > 10 (rank : 991)	NC score	0.074435 (rank : 656)
Query Neighborhood Hits	326	Target Neighborhood Hits	907	Shared Neighborhood Hits	41
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

RPGR1_HUMAN
θ value	θ > 10 (rank : 992)	NC score	0.080730 (rank : 579)
Query Neighborhood Hits	326	Target Neighborhood Hits	578	Shared Neighborhood Hits	85
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RPTN_MOUSE
θ value	θ > 10 (rank : 993)	NC score	0.056731 (rank : 1014)
Query Neighborhood Hits	326	Target Neighborhood Hits	650	Shared Neighborhood Hits	85
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RRBP1_HUMAN
θ value	θ > 10 (rank : 994)	NC score	0.117222 (rank : 251)
Query Neighborhood Hits	326	Target Neighborhood Hits	1306	Shared Neighborhood Hits	143
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RRP5_HUMAN
θ value	θ > 10 (rank : 995)	NC score	0.057455 (rank : 985)
Query Neighborhood Hits	326	Target Neighborhood Hits	291	Shared Neighborhood Hits	77
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

RUFY1_HUMAN
θ value	θ > 10 (rank : 996)	NC score	0.079598 (rank : 583)
Query Neighborhood Hits	326	Target Neighborhood Hits	848	Shared Neighborhood Hits	103
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY2_HUMAN
θ value	θ > 10 (rank : 997)	NC score	0.101752 (rank : 379)
Query Neighborhood Hits	326	Target Neighborhood Hits	1208	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	θ > 10 (rank : 998)	NC score	0.074700 (rank : 652)
Query Neighborhood Hits	326	Target Neighborhood Hits	820	Shared Neighborhood Hits	102
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RUFY3_HUMAN
θ value	θ > 10 (rank : 999)	NC score	0.087230 (rank : 515)
Query Neighborhood Hits	326	Target Neighborhood Hits	594	Shared Neighborhood Hits	110
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 1000)	NC score	0.085399 (rank : 537)
Query Neighborhood Hits	326	Target Neighborhood Hits	579	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RYK_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.079110 (rank : 595)
Query Neighborhood Hits	326	Target Neighborhood Hits	701	Shared Neighborhood Hits	41
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 1002)	NC score	0.078603 (rank : 604)
Query Neighborhood Hits	326	Target Neighborhood Hits	715	Shared Neighborhood Hits	41
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SAFB2_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.060960 (rank : 934)
Query Neighborhood Hits	326	Target Neighborhood Hits	720	Shared Neighborhood Hits	92
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SAS6_HUMAN
θ value	θ > 10 (rank : 1004)	NC score	0.088442 (rank : 499)
Query Neighborhood Hits	326	Target Neighborhood Hits	791	Shared Neighborhood Hits	103
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SAS6_MOUSE
θ value	θ > 10 (rank : 1005)	NC score	0.113387 (rank : 274)
Query Neighborhood Hits	326	Target Neighborhood Hits	931	Shared Neighborhood Hits	125
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SDCG8_HUMAN
θ value	θ > 10 (rank : 1006)	NC score	0.123450 (rank : 205)
Query Neighborhood Hits	326	Target Neighborhood Hits	1002	Shared Neighborhood Hits	147
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	θ > 10 (rank : 1007)	NC score	0.113285 (rank : 276)
Query Neighborhood Hits	326	Target Neighborhood Hits	886	Shared Neighborhood Hits	142
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SDPR_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.077139 (rank : 624)
Query Neighborhood Hits	326	Target Neighborhood Hits	337	Shared Neighborhood Hits	78
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SDPR_MOUSE
θ value	θ > 10 (rank : 1009)	NC score	0.103417 (rank : 365)
Query Neighborhood Hits	326	Target Neighborhood Hits	485	Shared Neighborhood Hits	113
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SDS3_HUMAN
θ value	θ > 10 (rank : 1010)	NC score	0.057395 (rank : 989)
Query Neighborhood Hits	326	Target Neighborhood Hits	257	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SDS3_MOUSE
θ value	θ > 10 (rank : 1011)	NC score	0.055549 (rank : 1045)
Query Neighborhood Hits	326	Target Neighborhood Hits	248	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SEC20_HUMAN
θ value	θ > 10 (rank : 1012)	NC score	0.050946 (rank : 1144)
Query Neighborhood Hits	326	Target Neighborhood Hits	200	Shared Neighborhood Hits	42
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

SEC20_MOUSE
θ value	θ > 10 (rank : 1013)	NC score	0.066072 (rank : 830)
Query Neighborhood Hits	326	Target Neighborhood Hits	323	Shared Neighborhood Hits	67
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

SEC63_HUMAN
θ value	θ > 10 (rank : 1014)	NC score	0.052426 (rank : 1105)
Query Neighborhood Hits	326	Target Neighborhood Hits	586	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
θ value	θ > 10 (rank : 1015)	NC score	0.052469 (rank : 1104)
Query Neighborhood Hits	326	Target Neighborhood Hits	601	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEMG2_HUMAN
θ value	θ > 10 (rank : 1016)	NC score	0.060213 (rank : 947)
Query Neighborhood Hits	326	Target Neighborhood Hits	251	Shared Neighborhood Hits	48
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SFR11_HUMAN
θ value	θ > 10 (rank : 1017)	NC score	0.066452 (rank : 819)
Query Neighborhood Hits	326	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFRIP_HUMAN
θ value	θ > 10 (rank : 1018)	NC score	0.076114 (rank : 640)
Query Neighborhood Hits	326	Target Neighborhood Hits	530	Shared Neighborhood Hits	72
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SH21A_HUMAN
θ value	θ > 10 (rank : 1019)	NC score	0.212353 (rank : 57)
Query Neighborhood Hits	326	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 1020)	NC score	0.219486 (rank : 54)
Query Neighborhood Hits	326	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH2D3_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.169172 (rank : 75)
Query Neighborhood Hits	326	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SH2D3_MOUSE
θ value	θ > 10 (rank : 1022)	NC score	0.166803 (rank : 76)
Query Neighborhood Hits	326	Target Neighborhood Hits	174	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SH3G1_HUMAN
θ value	θ > 10 (rank : 1023)	NC score	0.058581 (rank : 968)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G1_MOUSE
θ value	θ > 10 (rank : 1024)	NC score	0.057518 (rank : 983)
Query Neighborhood Hits	326	Target Neighborhood Hits	291	Shared Neighborhood Hits	56
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G2_HUMAN
θ value	θ > 10 (rank : 1025)	NC score	0.053468 (rank : 1080)
Query Neighborhood Hits	326	Target Neighborhood Hits	324	Shared Neighborhood Hits	51
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G3_MOUSE
θ value	θ > 10 (rank : 1026)	NC score	0.050102 (rank : 1164)
Query Neighborhood Hits	326	Target Neighborhood Hits	236	Shared Neighborhood Hits	42
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3K1_HUMAN
θ value	θ > 10 (rank : 1027)	NC score	0.065303 (rank : 852)
Query Neighborhood Hits	326	Target Neighborhood Hits	341	Shared Neighborhood Hits	52
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 1028)	NC score	0.062756 (rank : 899)
Query Neighborhood Hits	326	Target Neighborhood Hits	332	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SHC3_HUMAN
θ value	θ > 10 (rank : 1029)	NC score	0.232518 (rank : 52)
Query Neighborhood Hits	326	Target Neighborhood Hits	155	Shared Neighborhood Hits	78
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 1030)	NC score	0.232386 (rank : 53)
Query Neighborhood Hits	326	Target Neighborhood Hits	151	Shared Neighborhood Hits	81
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SKIL_MOUSE
θ value	θ > 10 (rank : 1031)	NC score	0.079666 (rank : 582)
Query Neighborhood Hits	326	Target Neighborhood Hits	719	Shared Neighborhood Hits	110
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SKI_HUMAN
θ value	θ > 10 (rank : 1032)	NC score	0.057624 (rank : 982)
Query Neighborhood Hits	326	Target Neighborhood Hits	423	Shared Neighborhood Hits	79
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

SKI_MOUSE
θ value	θ > 10 (rank : 1033)	NC score	0.058501 (rank : 970)
Query Neighborhood Hits	326	Target Neighborhood Hits	423	Shared Neighborhood Hits	82
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

SLAP2_HUMAN
θ value	θ > 10 (rank : 1034)	NC score	0.257288 (rank : 42)
Query Neighborhood Hits	326	Target Neighborhood Hits	139	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 1035)	NC score	0.252279 (rank : 45)
Query Neighborhood Hits	326	Target Neighborhood Hits	136	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SLK_HUMAN
θ value	θ > 10 (rank : 1036)	NC score	0.073711 (rank : 666)
Query Neighborhood Hits	326	Target Neighborhood Hits	1775	Shared Neighborhood Hits	174
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SLK_MOUSE
θ value	θ > 10 (rank : 1037)	NC score	0.074290 (rank : 657)
Query Neighborhood Hits	326	Target Neighborhood Hits	1798	Shared Neighborhood Hits	182
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SM1L2_HUMAN
θ value	θ > 10 (rank : 1038)	NC score	0.131820 (rank : 151)
Query Neighborhood Hits	326	Target Neighborhood Hits	1019	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SM1L2_MOUSE
θ value	θ > 10 (rank : 1039)	NC score	0.111184 (rank : 301)
Query Neighborhood Hits	326	Target Neighborhood Hits	918	Shared Neighborhood Hits	121
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SMC2_HUMAN
θ value	θ > 10 (rank : 1040)	NC score	0.144517 (rank : 108)
Query Neighborhood Hits	326	Target Neighborhood Hits	1405	Shared Neighborhood Hits	178
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC3_HUMAN
θ value	θ > 10 (rank : 1041)	NC score	0.124364 (rank : 198)
Query Neighborhood Hits	326	Target Neighborhood Hits	1186	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	θ > 10 (rank : 1042)	NC score	0.124310 (rank : 200)
Query Neighborhood Hits	326	Target Neighborhood Hits	1187	Shared Neighborhood Hits	157
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC4_HUMAN
θ value	θ > 10 (rank : 1043)	NC score	0.092235 (rank : 458)
Query Neighborhood Hits	326	Target Neighborhood Hits	937	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SMC4_MOUSE
θ value	θ > 10 (rank : 1044)	NC score	0.084658 (rank : 541)
Query Neighborhood Hits	326	Target Neighborhood Hits	830	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SNX23_HUMAN
θ value	θ > 10 (rank : 1045)	NC score	0.073123 (rank : 676)
Query Neighborhood Hits	326	Target Neighborhood Hits	944	Shared Neighborhood Hits	110
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

SOCS1_HUMAN
θ value	θ > 10 (rank : 1046)	NC score	0.089337 (rank : 492)
Query Neighborhood Hits	326	Target Neighborhood Hits	79	Shared Neighborhood Hits	43
SwissProt Accessions	O15524, O15097, Q9NSA7	Gene names	SOCS1, SSI1, TIP3
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3).

SOCS1_MOUSE
θ value	θ > 10 (rank : 1047)	NC score	0.090704 (rank : 472)
Query Neighborhood Hits	326	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	O35716, O35960, Q3U3L0	Gene names	Socs1, Cish1, Ssi1
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1).

SOCS2_HUMAN
θ value	θ > 10 (rank : 1048)	NC score	0.135494 (rank : 133)
Query Neighborhood Hits	326	Target Neighborhood Hits	104	Shared Neighborhood Hits	54
SwissProt Accessions	O14508, O14542, O95102, Q9UKS5	Gene names	SOCS2, CIS2, SSI2, STATI2
Domain Architecture
Description	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2).

SOCS2_MOUSE
θ value	θ > 10 (rank : 1049)	NC score	0.138262 (rank : 127)
Query Neighborhood Hits	326	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	O35717	Gene names	Socs2, Cis2, Cish2
Domain Architecture
Description	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2).

SOCS3_HUMAN
θ value	θ > 10 (rank : 1050)	NC score	0.104998 (rank : 352)
Query Neighborhood Hits	326	Target Neighborhood Hits	77	Shared Neighborhood Hits	45
SwissProt Accessions	O14543, O14509	Gene names	SOCS3, CIS3, SSI3
Domain Architecture
Description	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3).

SOCS3_MOUSE
θ value	θ > 10 (rank : 1051)	NC score	0.103938 (rank : 361)
Query Neighborhood Hits	326	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	O35718, P97803, Q3U7X5	Gene names	Socs3, Cis3, Cish3
Domain Architecture
Description	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (Protein EF-10).

SOCS4_HUMAN
θ value	θ > 10 (rank : 1052)	NC score	0.055804 (rank : 1040)
Query Neighborhood Hits	326	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXH5	Gene names	SOCS4, SOCS7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

SOCS4_MOUSE
θ value	θ > 10 (rank : 1053)	NC score	0.057021 (rank : 1006)
Query Neighborhood Hits	326	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZA6	Gene names	Socs4, Socs7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

SOCS5_HUMAN
θ value	θ > 10 (rank : 1054)	NC score	0.070801 (rank : 723)
Query Neighborhood Hits	326	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	O75159, Q8IYZ4	Gene names	SOCS5, CIS6, CISH5, CISH6, KIAA0671
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6).

SOCS5_MOUSE
θ value	θ > 10 (rank : 1055)	NC score	0.070578 (rank : 729)
Query Neighborhood Hits	326	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	O54928	Gene names	Socs5, Cish5
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5).

SOCS7_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.140661 (rank : 118)
Query Neighborhood Hits	326	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SPAG5_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.077566 (rank : 619)
Query Neighborhood Hits	326	Target Neighborhood Hits	625	Shared Neighborhood Hits	91
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

SPAG5_MOUSE
θ value	θ > 10 (rank : 1058)	NC score	0.072646 (rank : 685)
Query Neighborhood Hits	326	Target Neighborhood Hits	612	Shared Neighborhood Hits	79
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SPC24_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.078983 (rank : 599)
Query Neighborhood Hits	326	Target Neighborhood Hits	324	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

SPC25_HUMAN
θ value	θ > 10 (rank : 1060)	NC score	0.064717 (rank : 859)
Query Neighborhood Hits	326	Target Neighborhood Hits	273	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

SPC25_MOUSE
θ value	θ > 10 (rank : 1061)	NC score	0.051764 (rank : 1120)
Query Neighborhood Hits	326	Target Neighborhood Hits	241	Shared Neighborhood Hits	52
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

SPTA1_HUMAN
θ value	θ > 10 (rank : 1062)	NC score	0.075235 (rank : 647)
Query Neighborhood Hits	326	Target Neighborhood Hits	748	Shared Neighborhood Hits	120
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 1063)	NC score	0.071772 (rank : 706)
Query Neighborhood Hits	326	Target Neighborhood Hits	675	Shared Neighborhood Hits	109
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 1064)	NC score	0.088377 (rank : 502)
Query Neighborhood Hits	326	Target Neighborhood Hits	888	Shared Neighborhood Hits	130
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SPTB1_MOUSE
θ value	θ > 10 (rank : 1065)	NC score	0.051275 (rank : 1133)
Query Neighborhood Hits	326	Target Neighborhood Hits	543	Shared Neighborhood Hits	81
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB2_HUMAN
θ value	θ > 10 (rank : 1066)	NC score	0.066664 (rank : 815)
Query Neighborhood Hits	326	Target Neighborhood Hits	748	Shared Neighborhood Hits	106
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	θ > 10 (rank : 1067)	NC score	0.066263 (rank : 824)
Query Neighborhood Hits	326	Target Neighborhood Hits	770	Shared Neighborhood Hits	107
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SRBS1_HUMAN
θ value	θ > 10 (rank : 1068)	NC score	0.076911 (rank : 628)
Query Neighborhood Hits	326	Target Neighborhood Hits	396	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	θ > 10 (rank : 1069)	NC score	0.072829 (rank : 683)
Query Neighborhood Hits	326	Target Neighborhood Hits	409	Shared Neighborhood Hits	59
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	θ > 10 (rank : 1070)	NC score	0.057348 (rank : 992)
Query Neighborhood Hits	326	Target Neighborhood Hits	269	Shared Neighborhood Hits	47
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	θ > 10 (rank : 1071)	NC score	0.057380 (rank : 990)
Query Neighborhood Hits	326	Target Neighborhood Hits	292	Shared Neighborhood Hits	48
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRGP1_HUMAN
θ value	θ > 10 (rank : 1072)	NC score	0.051909 (rank : 1116)
Query Neighborhood Hits	326	Target Neighborhood Hits	390	Shared Neighborhood Hits	81
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRRM2_MOUSE
θ value	θ > 10 (rank : 1073)	NC score	0.053310 (rank : 1082)
Query Neighborhood Hits	326	Target Neighborhood Hits	1470	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SSNA1_MOUSE
θ value	θ > 10 (rank : 1074)	NC score	0.052688 (rank : 1100)
Query Neighborhood Hits	326	Target Neighborhood Hits	182	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JJ94	Gene names	Ssna1
Domain Architecture	No domain graphic available
Description	Sjoegren syndrome nuclear autoantigen 1 homolog.

STAC3_HUMAN
θ value	θ > 10 (rank : 1075)	NC score	0.061419 (rank : 921)
Query Neighborhood Hits	326	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 1076)	NC score	0.061913 (rank : 917)
Query Neighborhood Hits	326	Target Neighborhood Hits	232	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 1077)	NC score	0.054479 (rank : 1065)
Query Neighborhood Hits	326	Target Neighborhood Hits	276	Shared Neighborhood Hits	39
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 1078)	NC score	0.057044 (rank : 1004)
Query Neighborhood Hits	326	Target Neighborhood Hits	268	Shared Neighborhood Hits	36
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAM1_HUMAN
θ value	θ > 10 (rank : 1079)	NC score	0.064976 (rank : 855)
Query Neighborhood Hits	326	Target Neighborhood Hits	271	Shared Neighborhood Hits	37
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 1080)	NC score	0.065582 (rank : 844)
Query Neighborhood Hits	326	Target Neighborhood Hits	273	Shared Neighborhood Hits	37
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
θ value	θ > 10 (rank : 1081)	NC score	0.061977 (rank : 916)
Query Neighborhood Hits	326	Target Neighborhood Hits	288	Shared Neighborhood Hits	39
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	θ > 10 (rank : 1082)	NC score	0.061147 (rank : 930)
Query Neighborhood Hits	326	Target Neighborhood Hits	285	Shared Neighborhood Hits	41
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STIM1_HUMAN
θ value	θ > 10 (rank : 1083)	NC score	0.086378 (rank : 523)
Query Neighborhood Hits	326	Target Neighborhood Hits	665	Shared Neighborhood Hits	120
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
θ value	θ > 10 (rank : 1084)	NC score	0.089791 (rank : 484)
Query Neighborhood Hits	326	Target Neighborhood Hits	660	Shared Neighborhood Hits	125
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM2_HUMAN
θ value	θ > 10 (rank : 1085)	NC score	0.056270 (rank : 1025)
Query Neighborhood Hits	326	Target Neighborhood Hits	420	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

STIM2_MOUSE
θ value	θ > 10 (rank : 1086)	NC score	0.055995 (rank : 1034)
Query Neighborhood Hits	326	Target Neighborhood Hits	403	Shared Neighborhood Hits	90
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

STK10_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.095357 (rank : 423)
Query Neighborhood Hits	326	Target Neighborhood Hits	1921	Shared Neighborhood Hits	194
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STMN1_HUMAN
θ value	θ > 10 (rank : 1088)	NC score	0.124460 (rank : 196)
Query Neighborhood Hits	326	Target Neighborhood Hits	554	Shared Neighborhood Hits	133
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

STMN1_MOUSE
θ value	θ > 10 (rank : 1089)	NC score	0.124294 (rank : 201)
Query Neighborhood Hits	326	Target Neighborhood Hits	560	Shared Neighborhood Hits	132
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

STMN2_HUMAN
θ value	θ > 10 (rank : 1090)	NC score	0.080746 (rank : 577)
Query Neighborhood Hits	326	Target Neighborhood Hits	458	Shared Neighborhood Hits	94
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
θ value	θ > 10 (rank : 1091)	NC score	0.080746 (rank : 578)
Query Neighborhood Hits	326	Target Neighborhood Hits	458	Shared Neighborhood Hits	94
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN3_HUMAN
θ value	θ > 10 (rank : 1092)	NC score	0.078497 (rank : 606)
Query Neighborhood Hits	326	Target Neighborhood Hits	348	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NZ72, O75527, Q969Y4	Gene names	STMN3, SCLIP
Domain Architecture
Description	Stathmin-3 (SCG10-like protein).

STMN3_MOUSE
θ value	θ > 10 (rank : 1093)	NC score	0.066550 (rank : 817)
Query Neighborhood Hits	326	Target Neighborhood Hits	331	Shared Neighborhood Hits	83
SwissProt Accessions	O70166	Gene names	Stmn3, Sclip
Domain Architecture
Description	Stathmin-3 (SCG10-like protein) (SCG10-related protein HiAT3) (Hippocampus abundant transcript 3).

STMN4_HUMAN
θ value	θ > 10 (rank : 1094)	NC score	0.090025 (rank : 480)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	101
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
θ value	θ > 10 (rank : 1095)	NC score	0.090004 (rank : 481)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	101
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STX12_MOUSE
θ value	θ > 10 (rank : 1096)	NC score	0.055778 (rank : 1041)
Query Neighborhood Hits	326	Target Neighborhood Hits	283	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

STXB4_HUMAN
θ value	θ > 10 (rank : 1097)	NC score	0.064151 (rank : 872)
Query Neighborhood Hits	326	Target Neighborhood Hits	616	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 1098)	NC score	0.062685 (rank : 900)
Query Neighborhood Hits	326	Target Neighborhood Hits	629	Shared Neighborhood Hits	79
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STYK1_HUMAN
θ value	θ > 10 (rank : 1099)	NC score	0.079182 (rank : 594)
Query Neighborhood Hits	326	Target Neighborhood Hits	786	Shared Neighborhood Hits	41
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

STYK1_MOUSE
θ value	θ > 10 (rank : 1100)	NC score	0.079302 (rank : 588)
Query Neighborhood Hits	326	Target Neighborhood Hits	779	Shared Neighborhood Hits	41
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

SURF6_MOUSE
θ value	θ > 10 (rank : 1101)	NC score	0.063412 (rank : 885)
Query Neighborhood Hits	326	Target Neighborhood Hits	195	Shared Neighborhood Hits	40
SwissProt Accessions	P70279, Q8BPI4, Q8BRL7, Q8R0Q7	Gene names	Surf6, Surf-6
Domain Architecture
Description	Surfeit locus protein 6.

SWP70_HUMAN
θ value	θ > 10 (rank : 1102)	NC score	0.097549 (rank : 405)
Query Neighborhood Hits	326	Target Neighborhood Hits	973	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 1103)	NC score	0.112740 (rank : 284)
Query Neighborhood Hits	326	Target Neighborhood Hits	1097	Shared Neighborhood Hits	138
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYCP1_HUMAN
θ value	θ > 10 (rank : 1104)	NC score	0.125374 (rank : 189)
Query Neighborhood Hits	326	Target Neighborhood Hits	1313	Shared Neighborhood Hits	162
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYCP2_HUMAN
θ value	θ > 10 (rank : 1105)	NC score	0.059142 (rank : 960)
Query Neighborhood Hits	326	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

SYCP3_HUMAN
θ value	θ > 10 (rank : 1106)	NC score	0.051499 (rank : 1130)
Query Neighborhood Hits	326	Target Neighborhood Hits	276	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

SYGP1_HUMAN
θ value	θ > 10 (rank : 1107)	NC score	0.068416 (rank : 774)
Query Neighborhood Hits	326	Target Neighborhood Hits	589	Shared Neighborhood Hits	99
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

SYNE1_HUMAN
θ value	θ > 10 (rank : 1108)	NC score	0.083489 (rank : 548)
Query Neighborhood Hits	326	Target Neighborhood Hits	1484	Shared Neighborhood Hits	122
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYNE2_HUMAN
θ value	θ > 10 (rank : 1109)	NC score	0.083406 (rank : 549)
Query Neighborhood Hits	326	Target Neighborhood Hits	1323	Shared Neighborhood Hits	131
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

T2FA_HUMAN
θ value	θ > 10 (rank : 1110)	NC score	0.053179 (rank : 1085)
Query Neighborhood Hits	326	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

T2_MOUSE
θ value	θ > 10 (rank : 1111)	NC score	0.050345 (rank : 1159)
Query Neighborhood Hits	326	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

T3JAM_HUMAN
θ value	θ > 10 (rank : 1112)	NC score	0.083852 (rank : 545)
Query Neighborhood Hits	326	Target Neighborhood Hits	533	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

T3JAM_MOUSE
θ value	θ > 10 (rank : 1113)	NC score	0.065124 (rank : 854)
Query Neighborhood Hits	326	Target Neighborhood Hits	535	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TACC1_HUMAN
θ value	θ > 10 (rank : 1114)	NC score	0.087391 (rank : 512)
Query Neighborhood Hits	326	Target Neighborhood Hits	597	Shared Neighborhood Hits	104
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
θ value	θ > 10 (rank : 1115)	NC score	0.089941 (rank : 483)
Query Neighborhood Hits	326	Target Neighborhood Hits	667	Shared Neighborhood Hits	106
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TACC2_HUMAN
θ value	θ > 10 (rank : 1116)	NC score	0.104815 (rank : 355)
Query Neighborhood Hits	326	Target Neighborhood Hits	856	Shared Neighborhood Hits	119
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 1117)	NC score	0.094929 (rank : 432)
Query Neighborhood Hits	326	Target Neighborhood Hits	774	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TACC3_HUMAN
θ value	θ > 10 (rank : 1118)	NC score	0.087603 (rank : 510)
Query Neighborhood Hits	326	Target Neighborhood Hits	779	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TACC3_MOUSE
θ value	θ > 10 (rank : 1119)	NC score	0.089776 (rank : 485)
Query Neighborhood Hits	326	Target Neighborhood Hits	607	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TAD3L_HUMAN
θ value	θ > 10 (rank : 1120)	NC score	0.055607 (rank : 1043)
Query Neighborhood Hits	326	Target Neighborhood Hits	189	Shared Neighborhood Hits	57
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

TAD3L_MOUSE
θ value	θ > 10 (rank : 1121)	NC score	0.056444 (rank : 1021)
Query Neighborhood Hits	326	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

TAF4_HUMAN
θ value	θ > 10 (rank : 1122)	NC score	0.057870 (rank : 977)
Query Neighborhood Hits	326	Target Neighborhood Hits	687	Shared Neighborhood Hits	79
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TAOK1_MOUSE
θ value	θ > 10 (rank : 1123)	NC score	0.085463 (rank : 536)
Query Neighborhood Hits	326	Target Neighborhood Hits	1720	Shared Neighborhood Hits	185
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

TAOK2_HUMAN
θ value	θ > 10 (rank : 1124)	NC score	0.052895 (rank : 1093)
Query Neighborhood Hits	326	Target Neighborhood Hits	1172	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

TAOK3_HUMAN
θ value	θ > 10 (rank : 1125)	NC score	0.073429 (rank : 670)
Query Neighborhood Hits	326	Target Neighborhood Hits	1494	Shared Neighborhood Hits	147
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TAOK3_MOUSE
θ value	θ > 10 (rank : 1126)	NC score	0.069218 (rank : 751)
Query Neighborhood Hits	326	Target Neighborhood Hits	1458	Shared Neighborhood Hits	142
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

TARA_MOUSE
θ value	θ > 10 (rank : 1127)	NC score	0.086631 (rank : 521)
Query Neighborhood Hits	326	Target Neighborhood Hits	1133	Shared Neighborhood Hits	116
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAXB1_HUMAN
θ value	θ > 10 (rank : 1128)	NC score	0.116439 (rank : 258)
Query Neighborhood Hits	326	Target Neighborhood Hits	829	Shared Neighborhood Hits	127
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TAXB1_MOUSE
θ value	θ > 10 (rank : 1129)	NC score	0.105192 (rank : 347)
Query Neighborhood Hits	326	Target Neighborhood Hits	886	Shared Neighborhood Hits	117
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TCAL5_HUMAN
θ value	θ > 10 (rank : 1130)	NC score	0.081798 (rank : 568)
Query Neighborhood Hits	326	Target Neighborhood Hits	806	Shared Neighborhood Hits	101
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCRG1_HUMAN
θ value	θ > 10 (rank : 1131)	NC score	0.152003 (rank : 93)
Query Neighborhood Hits	326	Target Neighborhood Hits	929	Shared Neighborhood Hits	156
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 1132)	NC score	0.151985 (rank : 94)
Query Neighborhood Hits	326	Target Neighborhood Hits	947	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEC_HUMAN
θ value	θ > 10 (rank : 1133)	NC score	0.109026 (rank : 321)
Query Neighborhood Hits	326	Target Neighborhood Hits	1006	Shared Neighborhood Hits	86
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 1134)	NC score	0.105465 (rank : 346)
Query Neighborhood Hits	326	Target Neighborhood Hits	1006	Shared Neighborhood Hits	82
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEKT1_HUMAN
θ value	θ > 10 (rank : 1135)	NC score	0.060788 (rank : 940)
Query Neighborhood Hits	326	Target Neighborhood Hits	289	Shared Neighborhood Hits	60
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

TEKT1_MOUSE
θ value	θ > 10 (rank : 1136)	NC score	0.071603 (rank : 709)
Query Neighborhood Hits	326	Target Neighborhood Hits	399	Shared Neighborhood Hits	71
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

TESK1_HUMAN
θ value	θ > 10 (rank : 1137)	NC score	0.052043 (rank : 1113)
Query Neighborhood Hits	326	Target Neighborhood Hits	864	Shared Neighborhood Hits	46
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TESK1_MOUSE
θ value	θ > 10 (rank : 1138)	NC score	0.051692 (rank : 1124)
Query Neighborhood Hits	326	Target Neighborhood Hits	862	Shared Neighborhood Hits	42
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TESK2_HUMAN
θ value	θ > 10 (rank : 1139)	NC score	0.053384 (rank : 1081)
Query Neighborhood Hits	326	Target Neighborhood Hits	851	Shared Neighborhood Hits	44
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TESK2_MOUSE
θ value	θ > 10 (rank : 1140)	NC score	0.051724 (rank : 1121)
Query Neighborhood Hits	326	Target Neighborhood Hits	833	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TEX14_HUMAN
θ value	θ > 10 (rank : 1141)	NC score	0.090132 (rank : 478)
Query Neighborhood Hits	326	Target Neighborhood Hits	1103	Shared Neighborhood Hits	111
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_MOUSE
θ value	θ > 10 (rank : 1142)	NC score	0.095680 (rank : 421)
Query Neighborhood Hits	326	Target Neighborhood Hits	1333	Shared Neighborhood Hits	146
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX9_HUMAN
θ value	θ > 10 (rank : 1143)	NC score	0.080139 (rank : 581)
Query Neighborhood Hits	326	Target Neighborhood Hits	541	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TEX9_MOUSE
θ value	θ > 10 (rank : 1144)	NC score	0.091396 (rank : 467)
Query Neighborhood Hits	326	Target Neighborhood Hits	581	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TGON2_HUMAN
θ value	θ > 10 (rank : 1145)	NC score	0.072337 (rank : 689)
Query Neighborhood Hits	326	Target Neighborhood Hits	1037	Shared Neighborhood Hits	85
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIE1_HUMAN
θ value	θ > 10 (rank : 1146)	NC score	0.064740 (rank : 858)
Query Neighborhood Hits	326	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 1147)	NC score	0.064502 (rank : 863)
Query Neighborhood Hits	326	Target Neighborhood Hits	1266	Shared Neighborhood Hits	42
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 1148)	NC score	0.063920 (rank : 874)
Query Neighborhood Hits	326	Target Neighborhood Hits	1192	Shared Neighborhood Hits	40
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 1149)	NC score	0.063810 (rank : 878)
Query Neighborhood Hits	326	Target Neighborhood Hits	1204	Shared Neighborhood Hits	40
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TIM44_MOUSE
θ value	θ > 10 (rank : 1150)	NC score	0.073615 (rank : 667)
Query Neighborhood Hits	326	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

TLK2_MOUSE
θ value	θ > 10 (rank : 1151)	NC score	0.052024 (rank : 1114)
Query Neighborhood Hits	326	Target Neighborhood Hits	1088	Shared Neighborhood Hits	118
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

TNIK_HUMAN
θ value	θ > 10 (rank : 1152)	NC score	0.055511 (rank : 1048)
Query Neighborhood Hits	326	Target Neighborhood Hits	1570	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TNIP3_HUMAN
θ value	θ > 10 (rank : 1153)	NC score	0.088389 (rank : 500)
Query Neighborhood Hits	326	Target Neighborhood Hits	511	Shared Neighborhood Hits	88
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TNK1_HUMAN
θ value	θ > 10 (rank : 1154)	NC score	0.074162 (rank : 658)
Query Neighborhood Hits	326	Target Neighborhood Hits	815	Shared Neighborhood Hits	47
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 1155)	NC score	0.073243 (rank : 674)
Query Neighborhood Hits	326	Target Neighborhood Hits	806	Shared Neighborhood Hits	47
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TNNT2_HUMAN
θ value	θ > 10 (rank : 1156)	NC score	0.069274 (rank : 750)
Query Neighborhood Hits	326	Target Neighborhood Hits	433	Shared Neighborhood Hits	77
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TNNT2_MOUSE
θ value	θ > 10 (rank : 1157)	NC score	0.067378 (rank : 793)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	79
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TNNT3_HUMAN
θ value	θ > 10 (rank : 1158)	NC score	0.058858 (rank : 963)
Query Neighborhood Hits	326	Target Neighborhood Hits	327	Shared Neighborhood Hits	64
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

TNNT3_MOUSE
θ value	θ > 10 (rank : 1159)	NC score	0.082373 (rank : 561)
Query Neighborhood Hits	326	Target Neighborhood Hits	317	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

TOPK_HUMAN
θ value	θ > 10 (rank : 1160)	NC score	0.052963 (rank : 1092)
Query Neighborhood Hits	326	Target Neighborhood Hits	605	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

TOPK_MOUSE
θ value	θ > 10 (rank : 1161)	NC score	0.052528 (rank : 1102)
Query Neighborhood Hits	326	Target Neighborhood Hits	618	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

TPM1_HUMAN
θ value	θ > 10 (rank : 1162)	NC score	0.077884 (rank : 612)
Query Neighborhood Hits	326	Target Neighborhood Hits	716	Shared Neighborhood Hits	96
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	θ > 10 (rank : 1163)	NC score	0.078667 (rank : 603)
Query Neighborhood Hits	326	Target Neighborhood Hits	729	Shared Neighborhood Hits	98
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM2_HUMAN
θ value	θ > 10 (rank : 1164)	NC score	0.068795 (rank : 767)
Query Neighborhood Hits	326	Target Neighborhood Hits	677	Shared Neighborhood Hits	80
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM2_MOUSE
θ value	θ > 10 (rank : 1165)	NC score	0.068245 (rank : 778)
Query Neighborhood Hits	326	Target Neighborhood Hits	676	Shared Neighborhood Hits	82
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM3_HUMAN
θ value	θ > 10 (rank : 1166)	NC score	0.070088 (rank : 734)
Query Neighborhood Hits	326	Target Neighborhood Hits	689	Shared Neighborhood Hits	80
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

TPM3_MOUSE
θ value	θ > 10 (rank : 1167)	NC score	0.068687 (rank : 769)
Query Neighborhood Hits	326	Target Neighborhood Hits	676	Shared Neighborhood Hits	78
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

TPM4_HUMAN
θ value	θ > 10 (rank : 1168)	NC score	0.068206 (rank : 780)
Query Neighborhood Hits	326	Target Neighborhood Hits	525	Shared Neighborhood Hits	72
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

TPM4_MOUSE
θ value	θ > 10 (rank : 1169)	NC score	0.089965 (rank : 482)
Query Neighborhood Hits	326	Target Neighborhood Hits	703	Shared Neighborhood Hits	106
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TPR_HUMAN
θ value	θ > 10 (rank : 1170)	NC score	0.128811 (rank : 163)
Query Neighborhood Hits	326	Target Neighborhood Hits	1921	Shared Neighborhood Hits	174
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TR150_HUMAN
θ value	θ > 10 (rank : 1171)	NC score	0.054189 (rank : 1070)
Query Neighborhood Hits	326	Target Neighborhood Hits	313	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TR150_MOUSE
θ value	θ > 10 (rank : 1172)	NC score	0.114497 (rank : 267)
Query Neighborhood Hits	326	Target Neighborhood Hits	468	Shared Neighborhood Hits	113
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRAIP_HUMAN
θ value	θ > 10 (rank : 1173)	NC score	0.088710 (rank : 495)
Query Neighborhood Hits	326	Target Neighborhood Hits	780	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 1174)	NC score	0.089536 (rank : 488)
Query Neighborhood Hits	326	Target Neighborhood Hits	745	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRAK1_HUMAN
θ value	θ > 10 (rank : 1175)	NC score	0.082993 (rank : 553)
Query Neighborhood Hits	326	Target Neighborhood Hits	660	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

TRAK2_HUMAN
θ value	θ > 10 (rank : 1176)	NC score	0.066589 (rank : 816)
Query Neighborhood Hits	326	Target Neighborhood Hits	476	Shared Neighborhood Hits	75
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

TS101_HUMAN
θ value	θ > 10 (rank : 1177)	NC score	0.054429 (rank : 1067)
Query Neighborhood Hits	326	Target Neighborhood Hits	359	Shared Neighborhood Hits	66
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

TSC1_HUMAN
θ value	θ > 10 (rank : 1178)	NC score	0.098901 (rank : 395)
Query Neighborhood Hits	326	Target Neighborhood Hits	765	Shared Neighborhood Hits	98
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TTC1_HUMAN
θ value	θ > 10 (rank : 1179)	NC score	0.060257 (rank : 946)
Query Neighborhood Hits	326	Target Neighborhood Hits	417	Shared Neighborhood Hits	97
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TTC3_HUMAN
θ value	θ > 10 (rank : 1180)	NC score	0.052969 (rank : 1091)
Query Neighborhood Hits	326	Target Neighborhood Hits	664	Shared Neighborhood Hits	80
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TTF1_MOUSE
θ value	θ > 10 (rank : 1181)	NC score	0.057679 (rank : 980)
Query Neighborhood Hits	326	Target Neighborhood Hits	277	Shared Neighborhood Hits	69
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

TUFT1_HUMAN
θ value	θ > 10 (rank : 1182)	NC score	0.090309 (rank : 477)
Query Neighborhood Hits	326	Target Neighborhood Hits	686	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	θ > 10 (rank : 1183)	NC score	0.099788 (rank : 393)
Query Neighborhood Hits	326	Target Neighborhood Hits	732	Shared Neighborhood Hits	112
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

TXK_HUMAN
θ value	θ > 10 (rank : 1184)	NC score	0.117467 (rank : 248)
Query Neighborhood Hits	326	Target Neighborhood Hits	971	Shared Neighborhood Hits	91
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1185)	NC score	0.118861 (rank : 234)
Query Neighborhood Hits	326	Target Neighborhood Hits	980	Shared Neighborhood Hits	94
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TXLNA_HUMAN
θ value	θ > 10 (rank : 1186)	NC score	0.077515 (rank : 620)
Query Neighborhood Hits	326	Target Neighborhood Hits	982	Shared Neighborhood Hits	112
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNA_MOUSE
θ value	θ > 10 (rank : 1187)	NC score	0.076931 (rank : 627)
Query Neighborhood Hits	326	Target Neighborhood Hits	846	Shared Neighborhood Hits	107
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNB_HUMAN
θ value	θ > 10 (rank : 1188)	NC score	0.063560 (rank : 882)
Query Neighborhood Hits	326	Target Neighborhood Hits	912	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

TXLNB_MOUSE
θ value	θ > 10 (rank : 1189)	NC score	0.057290 (rank : 995)
Query Neighborhood Hits	326	Target Neighborhood Hits	640	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

TXLNG_HUMAN
θ value	θ > 10 (rank : 1190)	NC score	0.066716 (rank : 812)
Query Neighborhood Hits	326	Target Neighborhood Hits	568	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

TXLNG_MOUSE
θ value	θ > 10 (rank : 1191)	NC score	0.065336 (rank : 849)
Query Neighborhood Hits	326	Target Neighborhood Hits	552	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

TXND2_HUMAN
θ value	θ > 10 (rank : 1192)	NC score	0.061229 (rank : 927)
Query Neighborhood Hits	326	Target Neighborhood Hits	793	Shared Neighborhood Hits	66
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 1193)	NC score	0.130462 (rank : 156)
Query Neighborhood Hits	326	Target Neighborhood Hits	828	Shared Neighborhood Hits	129
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TYK2_HUMAN
θ value	θ > 10 (rank : 1194)	NC score	0.063190 (rank : 893)
Query Neighborhood Hits	326	Target Neighborhood Hits	841	Shared Neighborhood Hits	41
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYK2_MOUSE
θ value	θ > 10 (rank : 1195)	NC score	0.064065 (rank : 873)
Query Neighborhood Hits	326	Target Neighborhood Hits	850	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYRO3_HUMAN
θ value	θ > 10 (rank : 1196)	NC score	0.067963 (rank : 786)
Query Neighborhood Hits	326	Target Neighborhood Hits	995	Shared Neighborhood Hits	39
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	θ > 10 (rank : 1197)	NC score	0.068245 (rank : 779)
Query Neighborhood Hits	326	Target Neighborhood Hits	1007	Shared Neighborhood Hits	39
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

U2AFL_HUMAN
θ value	θ > 10 (rank : 1198)	NC score	0.072492 (rank : 687)
Query Neighborhood Hits	326	Target Neighborhood Hits	503	Shared Neighborhood Hits	79
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

U2AFM_HUMAN
θ value	θ > 10 (rank : 1199)	NC score	0.088639 (rank : 496)
Query Neighborhood Hits	326	Target Neighborhood Hits	577	Shared Neighborhood Hits	87
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

UACA_MOUSE
θ value	θ > 10 (rank : 1200)	NC score	0.107875 (rank : 330)
Query Neighborhood Hits	326	Target Neighborhood Hits	1620	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

UBF1_MOUSE
θ value	θ > 10 (rank : 1201)	NC score	0.068165 (rank : 781)
Query Neighborhood Hits	326	Target Neighborhood Hits	419	Shared Neighborhood Hits	65
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

UFO_HUMAN
θ value	θ > 10 (rank : 1202)	NC score	0.070710 (rank : 725)
Query Neighborhood Hits	326	Target Neighborhood Hits	981	Shared Neighborhood Hits	40
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 1203)	NC score	0.069928 (rank : 737)
Query Neighborhood Hits	326	Target Neighborhood Hits	988	Shared Neighborhood Hits	40
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

UTRO_HUMAN
θ value	θ > 10 (rank : 1204)	NC score	0.073090 (rank : 678)
Query Neighborhood Hits	326	Target Neighborhood Hits	960	Shared Neighborhood Hits	113
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

VAV_HUMAN
θ value	θ > 10 (rank : 1205)	NC score	0.162013 (rank : 79)
Query Neighborhood Hits	326	Target Neighborhood Hits	452	Shared Neighborhood Hits	84
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 1206)	NC score	0.149463 (rank : 98)
Query Neighborhood Hits	326	Target Neighborhood Hits	430	Shared Neighborhood Hits	78
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VDP_HUMAN
θ value	θ > 10 (rank : 1207)	NC score	0.078934 (rank : 600)
Query Neighborhood Hits	326	Target Neighborhood Hits	645	Shared Neighborhood Hits	87
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VDP_MOUSE
θ value	θ > 10 (rank : 1208)	NC score	0.060044 (rank : 950)
Query Neighborhood Hits	326	Target Neighborhood Hits	469	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VGFR1_HUMAN
θ value	θ > 10 (rank : 1209)	NC score	0.061307 (rank : 924)
Query Neighborhood Hits	326	Target Neighborhood Hits	1109	Shared Neighborhood Hits	41
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

VGFR1_MOUSE
θ value	θ > 10 (rank : 1210)	NC score	0.061285 (rank : 926)
Query Neighborhood Hits	326	Target Neighborhood Hits	1118	Shared Neighborhood Hits	41
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

VGFR2_HUMAN
θ value	θ > 10 (rank : 1211)	NC score	0.062600 (rank : 905)
Query Neighborhood Hits	326	Target Neighborhood Hits	1103	Shared Neighborhood Hits	42
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

VGFR2_MOUSE
θ value	θ > 10 (rank : 1212)	NC score	0.062673 (rank : 901)
Query Neighborhood Hits	326	Target Neighborhood Hits	1089	Shared Neighborhood Hits	42
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

VGFR3_HUMAN
θ value	θ > 10 (rank : 1213)	NC score	0.063572 (rank : 881)
Query Neighborhood Hits	326	Target Neighborhood Hits	1037	Shared Neighborhood Hits	41
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VGFR3_MOUSE
θ value	θ > 10 (rank : 1214)	NC score	0.063363 (rank : 889)
Query Neighborhood Hits	326	Target Neighborhood Hits	1056	Shared Neighborhood Hits	41
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VIME_HUMAN
θ value	θ > 10 (rank : 1215)	NC score	0.052301 (rank : 1107)
Query Neighborhood Hits	326	Target Neighborhood Hits	706	Shared Neighborhood Hits	94
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

VIME_MOUSE
θ value	θ > 10 (rank : 1216)	NC score	0.052767 (rank : 1098)
Query Neighborhood Hits	326	Target Neighborhood Hits	716	Shared Neighborhood Hits	97
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

VINEX_HUMAN
θ value	θ > 10 (rank : 1217)	NC score	0.063121 (rank : 896)
Query Neighborhood Hits	326	Target Neighborhood Hits	270	Shared Neighborhood Hits	42
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 1218)	NC score	0.061157 (rank : 929)
Query Neighborhood Hits	326	Target Neighborhood Hits	286	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

WDR60_MOUSE
θ value	θ > 10 (rank : 1219)	NC score	0.077417 (rank : 623)
Query Neighborhood Hits	326	Target Neighborhood Hits	344	Shared Neighborhood Hits	75
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

WDR67_HUMAN
θ value	θ > 10 (rank : 1220)	NC score	0.101548 (rank : 380)
Query Neighborhood Hits	326	Target Neighborhood Hits	782	Shared Neighborhood Hits	111
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

XE7_HUMAN
θ value	θ > 10 (rank : 1221)	NC score	0.116131 (rank : 260)
Query Neighborhood Hits	326	Target Neighborhood Hits	738	Shared Neighborhood Hits	105
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

YES_HUMAN
θ value	θ > 10 (rank : 1222)	NC score	0.130505 (rank : 155)
Query Neighborhood Hits	326	Target Neighborhood Hits	1059	Shared Neighborhood Hits	99
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 1223)	NC score	0.130173 (rank : 157)
Query Neighborhood Hits	326	Target Neighborhood Hits	1052	Shared Neighborhood Hits	99
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YO11_MOUSE
θ value	θ > 10 (rank : 1224)	NC score	0.050589 (rank : 1152)
Query Neighborhood Hits	326	Target Neighborhood Hits	272	Shared Neighborhood Hits	53
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

YTDC1_HUMAN
θ value	θ > 10 (rank : 1225)	NC score	0.094114 (rank : 440)
Query Neighborhood Hits	326	Target Neighborhood Hits	458	Shared Neighborhood Hits	76
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZCPW1_MOUSE
θ value	θ > 10 (rank : 1226)	NC score	0.050746 (rank : 1150)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	57
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ZN318_HUMAN
θ value	θ > 10 (rank : 1227)	NC score	0.057075 (rank : 1003)
Query Neighborhood Hits	326	Target Neighborhood Hits	497	Shared Neighborhood Hits	96
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ZN318_MOUSE
θ value	θ > 10 (rank : 1228)	NC score	0.094154 (rank : 439)
Query Neighborhood Hits	326	Target Neighborhood Hits	642	Shared Neighborhood Hits	108
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ZWINT_HUMAN
θ value	θ > 10 (rank : 1229)	NC score	0.079051 (rank : 598)
Query Neighborhood Hits	326	Target Neighborhood Hits	333	Shared Neighborhood Hits	68
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

ZWINT_MOUSE
θ value	θ > 10 (rank : 1230)	NC score	0.097125 (rank : 410)
Query Neighborhood Hits	326	Target Neighborhood Hits	497	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

Hits sorted by NC score

SH24A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	326	Target Neighborhood Hits	326	Shared Neighborhood Hits	326
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

SH24A_HUMAN
NC score	0.829632 (rank : 2)	θ value	4.39142e-172 (rank : 2)
Query Neighborhood Hits	326	Target Neighborhood Hits	455	Shared Neighborhood Hits	194
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

HSH2D_MOUSE
NC score	0.616340 (rank : 3)	θ value	5.25075e-16 (rank : 3)
Query Neighborhood Hits	326	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HSH2D_HUMAN
NC score	0.604287 (rank : 4)	θ value	9.90251e-15 (rank : 4)
Query Neighborhood Hits	326	Target Neighborhood Hits	159	Shared Neighborhood Hits	83
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

SH22A_MOUSE
NC score	0.544818 (rank : 5)	θ value	2.98157e-11 (rank : 5)
Query Neighborhood Hits	326	Target Neighborhood Hits	179	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH22A_HUMAN
NC score	0.529761 (rank : 6)	θ value	4.30538e-10 (rank : 6)
Query Neighborhood Hits	326	Target Neighborhood Hits	144	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SHD_MOUSE
NC score	0.443241 (rank : 7)	θ value	8.40245e-06 (rank : 8)
Query Neighborhood Hits	326	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHD_HUMAN
NC score	0.422888 (rank : 8)	θ value	5.44631e-05 (rank : 12)
Query Neighborhood Hits	326	Target Neighborhood Hits	204	Shared Neighborhood Hits	89
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHE_HUMAN
NC score	0.386745 (rank : 9)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	326	Target Neighborhood Hits	164	Shared Neighborhood Hits	85
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

DAPP1_HUMAN
NC score	0.385807 (rank : 10)	θ value	3.19293e-05 (rank : 10)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
NC score	0.379399 (rank : 11)	θ value	5.44631e-05 (rank : 11)
Query Neighborhood Hits	326	Target Neighborhood Hits	225	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

SHE_MOUSE
NC score	0.377307 (rank : 12)	θ value	0.0113563 (rank : 45)
Query Neighborhood Hits	326	Target Neighborhood Hits	169	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

APS_HUMAN
NC score	0.362254 (rank : 13)	θ value	0.00102713 (rank : 26)
Query Neighborhood Hits	326	Target Neighborhood Hits	162	Shared Neighborhood Hits	83
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

SHB_MOUSE
NC score	0.340631 (rank : 14)	θ value	0.0148317 (rank : 50)
Query Neighborhood Hits	326	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

LNK_HUMAN
NC score	0.337124 (rank : 15)	θ value	0.0252991 (rank : 57)
Query Neighborhood Hits	326	Target Neighborhood Hits	151	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

SHB_HUMAN
NC score	0.336151 (rank : 16)	θ value	0.0252991 (rank : 59)
Query Neighborhood Hits	326	Target Neighborhood Hits	141	Shared Neighborhood Hits	85
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

LNK_MOUSE
NC score	0.330812 (rank : 17)	θ value	0.0563607 (rank : 74)
Query Neighborhood Hits	326	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

P55G_HUMAN
NC score	0.323183 (rank : 18)	θ value	0.00869519 (rank : 40)
Query Neighborhood Hits	326	Target Neighborhood Hits	451	Shared Neighborhood Hits	149
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
NC score	0.319315 (rank : 19)	θ value	0.00869519 (rank : 41)
Query Neighborhood Hits	326	Target Neighborhood Hits	401	Shared Neighborhood Hits	144
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

APS_MOUSE
NC score	0.317054 (rank : 20)	θ value	0.00869519 (rank : 38)
Query Neighborhood Hits	326	Target Neighborhood Hits	134	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

P85B_MOUSE
NC score	0.312955 (rank : 21)	θ value	0.0563607 (rank : 75)
Query Neighborhood Hits	326	Target Neighborhood Hits	519	Shared Neighborhood Hits	160
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_HUMAN
NC score	0.312459 (rank : 22)	θ value	0.0193708 (rank : 55)
Query Neighborhood Hits	326	Target Neighborhood Hits	543	Shared Neighborhood Hits	164
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PLCG1_HUMAN
NC score	0.311538 (rank : 23)	θ value	0.000121331 (rank : 15)
Query Neighborhood Hits	326	Target Neighborhood Hits	293	Shared Neighborhood Hits	87
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
NC score	0.309842 (rank : 24)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	326	Target Neighborhood Hits	314	Shared Neighborhood Hits	88
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SHC1_MOUSE
NC score	0.303654 (rank : 25)	θ value	0.00102713 (rank : 29)
Query Neighborhood Hits	326	Target Neighborhood Hits	180	Shared Neighborhood Hits	87
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

RASA1_HUMAN
NC score	0.301798 (rank : 26)	θ value	0.00175202 (rank : 31)
Query Neighborhood Hits	326	Target Neighborhood Hits	258	Shared Neighborhood Hits	88
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

GRB2_MOUSE
NC score	0.300437 (rank : 27)	θ value	0.00020696 (rank : 18)
Query Neighborhood Hits	326	Target Neighborhood Hits	312	Shared Neighborhood Hits	92
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRB2_HUMAN
NC score	0.298536 (rank : 28)	θ value	0.00035302 (rank : 21)
Query Neighborhood Hits	326	Target Neighborhood Hits	310	Shared Neighborhood Hits	90
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRAP2_HUMAN
NC score	0.297392 (rank : 29)	θ value	0.00509761 (rank : 34)
Query Neighborhood Hits	326	Target Neighborhood Hits	304	Shared Neighborhood Hits	89
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

SHC1_HUMAN
NC score	0.297049 (rank : 30)	θ value	0.00102713 (rank : 28)
Query Neighborhood Hits	326	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

GRAP2_MOUSE
NC score	0.289647 (rank : 31)	θ value	0.0431538 (rank : 66)
Query Neighborhood Hits	326	Target Neighborhood Hits	297	Shared Neighborhood Hits	88
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

PLCG2_HUMAN
NC score	0.287690 (rank : 32)	θ value	0.62314 (rank : 142)
Query Neighborhood Hits	326	Target Neighborhood Hits	280	Shared Neighborhood Hits	88
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

GRAP_MOUSE
NC score	0.278531 (rank : 33)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	326	Target Neighborhood Hits	309	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SH21B_MOUSE
NC score	0.277092 (rank : 34)	θ value	0.365318 (rank : 124)
Query Neighborhood Hits	326	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

GRAP_HUMAN
NC score	0.276641 (rank : 35)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	87
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

NCK2_HUMAN
NC score	0.273496 (rank : 36)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	326	Target Neighborhood Hits	310	Shared Neighborhood Hits	92
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCK1_HUMAN
NC score	0.270952 (rank : 37)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	326	Target Neighborhood Hits	312	Shared Neighborhood Hits	87
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

P85A_HUMAN
NC score	0.268854 (rank : 38)	θ value	0.0113563 (rank : 44)
Query Neighborhood Hits	326	Target Neighborhood Hits	479	Shared Neighborhood Hits	126
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.268360 (rank : 39)	θ value	0.0193708 (rank : 54)
Query Neighborhood Hits	326	Target Neighborhood Hits	435	Shared Neighborhood Hits	119
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SH21B_HUMAN
NC score	0.264872 (rank : 40)	θ value	1.38821 (rank : 189)
Query Neighborhood Hits	326	Target Neighborhood Hits	101	Shared Neighborhood Hits	61
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

CRKL_MOUSE
NC score	0.259951 (rank : 41)	θ value	0.21417 (rank : 103)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	92
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

SLAP2_HUMAN
NC score	0.257288 (rank : 42)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	326	Target Neighborhood Hits	139	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

CRKL_HUMAN
NC score	0.255655 (rank : 43)	θ value	0.62314 (rank : 137)
Query Neighborhood Hits	326	Target Neighborhood Hits	313	Shared Neighborhood Hits	92
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

GRB7_MOUSE
NC score	0.252429 (rank : 44)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	326	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

SLAP2_MOUSE
NC score	0.252279 (rank : 45)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	326	Target Neighborhood Hits	136	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SHC2_MOUSE
NC score	0.252206 (rank : 46)	θ value	0.62314 (rank : 144)
Query Neighborhood Hits	326	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC2_HUMAN
NC score	0.250559 (rank : 47)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	326	Target Neighborhood Hits	170	Shared Neighborhood Hits	81
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SLAP1_HUMAN
NC score	0.243901 (rank : 48)	θ value	0.47712 (rank : 134)
Query Neighborhood Hits	326	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
NC score	0.242686 (rank : 49)	θ value	0.813845 (rank : 160)
Query Neighborhood Hits	326	Target Neighborhood Hits	117	Shared Neighborhood Hits	75
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

CRK_HUMAN
NC score	0.238301 (rank : 50)	θ value	5.27518 (rank : 263)
Query Neighborhood Hits	326	Target Neighborhood Hits	308	Shared Neighborhood Hits	91
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
NC score	0.236695 (rank : 51)	θ value	5.27518 (rank : 264)
Query Neighborhood Hits	326	Target Neighborhood Hits	314	Shared Neighborhood Hits	91
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

SHC3_HUMAN
NC score	0.232518 (rank : 52)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	326	Target Neighborhood Hits	155	Shared Neighborhood Hits	78
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
NC score	0.232386 (rank : 53)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	326	Target Neighborhood Hits	151	Shared Neighborhood Hits	81
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SH21A_MOUSE
NC score	0.219486 (rank : 54)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	326	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

GRB7_HUMAN
NC score	0.217179 (rank : 55)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	326	Target Neighborhood Hits	156	Shared Neighborhood Hits	83
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

SH23A_HUMAN
NC score	0.216365 (rank : 56)	θ value	1.81305 (rank : 206)
Query Neighborhood Hits	326	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

SH21A_HUMAN
NC score	0.212353 (rank : 57)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	326	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

GRB14_HUMAN
NC score	0.210224 (rank : 58)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	326	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

PTN11_MOUSE
NC score	0.208123 (rank : 59)	θ value	0.000270298 (rank : 20)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	89
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.208099 (rank : 60)	θ value	0.000270298 (rank : 19)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	89
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

GRB14_MOUSE
NC score	0.207032 (rank : 61)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	326	Target Neighborhood Hits	149	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

PTN6_MOUSE
NC score	0.187154 (rank : 62)	θ value	1.87187e-05 (rank : 9)
Query Neighborhood Hits	326	Target Neighborhood Hits	225	Shared Neighborhood Hits	90
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

MAP1A_HUMAN
NC score	0.181721 (rank : 63)	θ value	0.00298849 (rank : 33)
Query Neighborhood Hits	326	Target Neighborhood Hits	1626	Shared Neighborhood Hits	183
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

VAV3_HUMAN
NC score	0.180681 (rank : 64)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	326	Target Neighborhood Hits	398	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
NC score	0.180565 (rank : 65)	θ value	5.27518 (rank : 282)
Query Neighborhood Hits	326	Target Neighborhood Hits	404	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV2_HUMAN
NC score	0.179652 (rank : 66)	θ value	0.62314 (rank : 149)
Query Neighborhood Hits	326	Target Neighborhood Hits	453	Shared Neighborhood Hits	88
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

BCAR3_HUMAN
NC score	0.178787 (rank : 67)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	326	Target Neighborhood Hits	129	Shared Neighborhood Hits	76
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

SOCS6_MOUSE
NC score	0.178664 (rank : 68)	θ value	1.06291 (rank : 171)
Query Neighborhood Hits	326	Target Neighborhood Hits	146	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

BCAR3_MOUSE
NC score	0.175959 (rank : 69)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	326	Target Neighborhood Hits	127	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

MAP9_HUMAN
NC score	0.173997 (rank : 70)	θ value	0.00509761 (rank : 36)
Query Neighborhood Hits	326	Target Neighborhood Hits	518	Shared Neighborhood Hits	88
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

SOCS6_HUMAN
NC score	0.173923 (rank : 71)	θ value	1.06291 (rank : 170)
Query Neighborhood Hits	326	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	O14544	Gene names	SOCS6, CIS4, SOCS4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

VAV2_MOUSE
NC score	0.173896 (rank : 72)	θ value	1.38821 (rank : 190)
Query Neighborhood Hits	326	Target Neighborhood Hits	456	Shared Neighborhood Hits	85
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

TENS4_MOUSE
NC score	0.170987 (rank : 73)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	326	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

GRB10_HUMAN
NC score	0.170704 (rank : 74)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	326	Target Neighborhood Hits	147	Shared Neighborhood Hits	80
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

SH2D3_HUMAN
NC score	0.169172 (rank : 75)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	326	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SH2D3_MOUSE
NC score	0.166803 (rank : 76)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	326	Target Neighborhood Hits	174	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

GRB10_MOUSE
NC score	0.165291 (rank : 77)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	326	Target Neighborhood Hits	156	Shared Neighborhood Hits	79
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

SFR12_HUMAN
NC score	0.164545 (rank : 78)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	326	Target Neighborhood Hits	553	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

VAV_HUMAN
NC score	0.162013 (rank : 79)	θ value	θ > 10 (rank : 1205)
Query Neighborhood Hits	326	Target Neighborhood Hits	452	Shared Neighborhood Hits	84
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

PTN6_HUMAN
NC score	0.161228 (rank : 80)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	326	Target Neighborhood Hits	234	Shared Neighborhood Hits	90
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

RBBP6_HUMAN
NC score	0.159411 (rank : 81)	θ value	0.0736092 (rank : 79)
Query Neighborhood Hits	326	Target Neighborhood Hits	1135	Shared Neighborhood Hits	132
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CCD46_MOUSE
NC score	0.158986 (rank : 82)	θ value	0.0961366 (rank : 80)
Query Neighborhood Hits	326	Target Neighborhood Hits	1405	Shared Neighborhood Hits	178
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

MAP9_MOUSE
NC score	0.157389 (rank : 83)	θ value	0.0330416 (rank : 61)
Query Neighborhood Hits	326	Target Neighborhood Hits	529	Shared Neighborhood Hits	79
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

ABL2_HUMAN
NC score	0.157121 (rank : 84)	θ value	0.00020696 (rank : 17)
Query Neighborhood Hits	326	Target Neighborhood Hits	1045	Shared Neighborhood Hits	107
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABL1_HUMAN
NC score	0.156909 (rank : 85)	θ value	7.1131e-05 (rank : 13)
Query Neighborhood Hits	326	Target Neighborhood Hits	1220	Shared Neighborhood Hits	116
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
NC score	0.156444 (rank : 86)	θ value	7.1131e-05 (rank : 14)
Query Neighborhood Hits	326	Target Neighborhood Hits	1178	Shared Neighborhood Hits	110
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CCD46_HUMAN
NC score	0.156013 (rank : 87)	θ value	0.0193708 (rank : 52)
Query Neighborhood Hits	326	Target Neighborhood Hits	1430	Shared Neighborhood Hits	162
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

SMC1A_MOUSE
NC score	0.154412 (rank : 88)	θ value	1.06291 (rank : 169)
Query Neighborhood Hits	326	Target Neighborhood Hits	1384	Shared Neighborhood Hits	174
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TENS4_HUMAN
NC score	0.154310 (rank : 89)	θ value	0.0961366 (rank : 88)
Query Neighborhood Hits	326	Target Neighborhood Hits	214	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

IF2P_HUMAN
NC score	0.154167 (rank : 90)	θ value	0.0113563 (rank : 43)
Query Neighborhood Hits	326	Target Neighborhood Hits	889	Shared Neighborhood Hits	100
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CAF1A_HUMAN
NC score	0.152685 (rank : 91)	θ value	0.0113563 (rank : 42)
Query Neighborhood Hits	326	Target Neighborhood Hits	750	Shared Neighborhood Hits	101
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

ACINU_HUMAN
NC score	0.152632 (rank : 92)	θ value	1.38821 (rank : 176)
Query Neighborhood Hits	326	Target Neighborhood Hits	828	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TCRG1_HUMAN
NC score	0.152003 (rank : 93)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	326	Target Neighborhood Hits	929	Shared Neighborhood Hits	156
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.151985 (rank : 94)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	326	Target Neighborhood Hits	947	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

IF3A_HUMAN
NC score	0.151834 (rank : 95)	θ value	0.0961366 (rank : 82)
Query Neighborhood Hits	326	Target Neighborhood Hits	875	Shared Neighborhood Hits	128
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

CI039_HUMAN
NC score	0.151184 (rank : 96)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	326	Target Neighborhood Hits	1171	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

FER_HUMAN
NC score	0.150688 (rank : 97)	θ value	0.00102713 (rank : 27)
Query Neighborhood Hits	326	Target Neighborhood Hits	1278	Shared Neighborhood Hits	175
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

VAV_MOUSE
NC score	0.149463 (rank : 98)	θ value	θ > 10 (rank : 1206)
Query Neighborhood Hits	326	Target Neighborhood Hits	430	Shared Neighborhood Hits	78
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

FGR_MOUSE
NC score	0.149165 (rank : 99)	θ value	0.279714 (rank : 115)
Query Neighborhood Hits	326	Target Neighborhood Hits	1069	Shared Neighborhood Hits	104
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

IF3A_MOUSE
NC score	0.148957 (rank : 100)	θ value	0.0961366 (rank : 83)
Query Neighborhood Hits	326	Target Neighborhood Hits	871	Shared Neighborhood Hits	123
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

SMC1A_HUMAN
NC score	0.148886 (rank : 101)	θ value	1.06291 (rank : 168)
Query Neighborhood Hits	326	Target Neighborhood Hits	1346	Shared Neighborhood Hits	169
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

MY18A_MOUSE
NC score	0.146966 (rank : 102)	θ value	0.0148317 (rank : 48)
Query Neighborhood Hits	326	Target Neighborhood Hits	1989	Shared Neighborhood Hits	199
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CAF1A_MOUSE
NC score	0.145864 (rank : 103)	θ value	0.21417 (rank : 101)
Query Neighborhood Hits	326	Target Neighborhood Hits	736	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CN145_HUMAN
NC score	0.145558 (rank : 104)	θ value	0.0431538 (rank : 65)
Query Neighborhood Hits	326	Target Neighborhood Hits	1196	Shared Neighborhood Hits	156
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

GOGB1_HUMAN
NC score	0.145492 (rank : 105)	θ value	0.0252991 (rank : 56)
Query Neighborhood Hits	326	Target Neighborhood Hits	2297	Shared Neighborhood Hits	194
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NOP14_HUMAN
NC score	0.145366 (rank : 106)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	326	Target Neighborhood Hits	573	Shared Neighborhood Hits	136
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

SFR12_MOUSE
NC score	0.144604 (rank : 107)	θ value	0.0563607 (rank : 76)
Query Neighborhood Hits	326	Target Neighborhood Hits	486	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SMC2_HUMAN
NC score	0.144517 (rank : 108)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	326	Target Neighborhood Hits	1405	Shared Neighborhood Hits	178
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CSK_MOUSE
NC score	0.144075 (rank : 109)	θ value	0.00869519 (rank : 39)
Query Neighborhood Hits	326	Target Neighborhood Hits	1009	Shared Neighborhood Hits	103
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

RBBP6_MOUSE
NC score	0.143592 (rank : 110)	θ value	0.365318 (rank : 123)
Query Neighborhood Hits	326	Target Neighborhood Hits	1014	Shared Neighborhood Hits	113
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

CSK_HUMAN
NC score	0.142776 (rank : 111)	θ value	0.0148317 (rank : 47)
Query Neighborhood Hits	326	Target Neighborhood Hits	1009	Shared Neighborhood Hits	103
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

SYCP1_MOUSE
NC score	0.142256 (rank : 112)	θ value	0.62314 (rank : 145)
Query Neighborhood Hits	326	Target Neighborhood Hits	1456	Shared Neighborhood Hits	172
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

MY18A_HUMAN
NC score	0.142211 (rank : 113)	θ value	0.0961366 (rank : 84)
Query Neighborhood Hits	326	Target Neighborhood Hits	1929	Shared Neighborhood Hits	198
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CK5P2_HUMAN
NC score	0.142079 (rank : 114)	θ value	2.36792 (rank : 210)
Query Neighborhood Hits	326	Target Neighborhood Hits	1433	Shared Neighborhood Hits	180
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

NIPBL_HUMAN
NC score	0.141736 (rank : 115)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	326	Target Neighborhood Hits	1311	Shared Neighborhood Hits	150
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TRHY_HUMAN
NC score	0.141134 (rank : 116)	θ value	0.000602161 (rank : 23)
Query Neighborhood Hits	326	Target Neighborhood Hits	1385	Shared Neighborhood Hits	131
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

KSYK_MOUSE
NC score	0.140704 (rank : 117)	θ value	0.000786445 (rank : 25)
Query Neighborhood Hits	326	Target Neighborhood Hits	944	Shared Neighborhood Hits	95
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

SOCS7_MOUSE
NC score	0.140661 (rank : 118)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	326	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

FGR_HUMAN
NC score	0.140319 (rank : 119)	θ value	1.81305 (rank : 198)
Query Neighborhood Hits	326	Target Neighborhood Hits	1067	Shared Neighborhood Hits	100
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ITSN1_MOUSE
NC score	0.140190 (rank : 120)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	326	Target Neighborhood Hits	1669	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

REN3B_HUMAN
NC score	0.139585 (rank : 121)	θ value	0.21417 (rank : 110)
Query Neighborhood Hits	326	Target Neighborhood Hits	412	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

NEST_HUMAN
NC score	0.139584 (rank : 122)	θ value	0.0961366 (rank : 86)
Query Neighborhood Hits	326	Target Neighborhood Hits	1305	Shared Neighborhood Hits	160
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CCD41_MOUSE
NC score	0.139405 (rank : 123)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	326	Target Neighborhood Hits	1399	Shared Neighborhood Hits	173
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD96_MOUSE
NC score	0.138979 (rank : 124)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	326	Target Neighborhood Hits	704	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

SRMS_HUMAN
NC score	0.138956 (rank : 125)	θ value	0.0113563 (rank : 46)
Query Neighborhood Hits	326	Target Neighborhood Hits	946	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

KSYK_HUMAN
NC score	0.138654 (rank : 126)	θ value	0.00509761 (rank : 35)
Query Neighborhood Hits	326	Target Neighborhood Hits	901	Shared Neighborhood Hits	95
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

SOCS2_MOUSE
NC score	0.138262 (rank : 127)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	326	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	O35717	Gene names	Socs2, Cis2, Cish2
Domain Architecture
Description	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2).

RRBP1_MOUSE
NC score	0.138174 (rank : 128)	θ value	1.81305 (rank : 204)
Query Neighborhood Hits	326	Target Neighborhood Hits	1650	Shared Neighborhood Hits	177
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

FYN_HUMAN
NC score	0.138102 (rank : 129)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	326	Target Neighborhood Hits	1078	Shared Neighborhood Hits	102
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

CT2NL_HUMAN
NC score	0.137830 (rank : 130)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	326	Target Neighborhood Hits	1059	Shared Neighborhood Hits	166
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

PTK6_MOUSE
NC score	0.136238 (rank : 131)	θ value	0.00175202 (rank : 30)
Query Neighborhood Hits	326	Target Neighborhood Hits	1026	Shared Neighborhood Hits	94
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

MAP1B_HUMAN
NC score	0.135687 (rank : 132)	θ value	0.21417 (rank : 108)
Query Neighborhood Hits	326	Target Neighborhood Hits	903	Shared Neighborhood Hits	103
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SOCS2_HUMAN
NC score	0.135494 (rank : 133)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	326	Target Neighborhood Hits	104	Shared Neighborhood Hits	54
SwissProt Accessions	O14508, O14542, O95102, Q9UKS5	Gene names	SOCS2, CIS2, SSI2, STATI2
Domain Architecture
Description	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2).

FRK_HUMAN
NC score	0.135172 (rank : 134)	θ value	0.279714 (rank : 116)
Query Neighborhood Hits	326	Target Neighborhood Hits	1058	Shared Neighborhood Hits	98
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

PTK6_HUMAN
NC score	0.134860 (rank : 135)	θ value	0.00228821 (rank : 32)
Query Neighborhood Hits	326	Target Neighborhood Hits	1020	Shared Neighborhood Hits	94
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

CE290_HUMAN
NC score	0.134857 (rank : 136)	θ value	0.47712 (rank : 127)
Query Neighborhood Hits	326	Target Neighborhood Hits	1553	Shared Neighborhood Hits	161
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

SRMS_MOUSE
NC score	0.134456 (rank : 137)	θ value	0.0148317 (rank : 51)
Query Neighborhood Hits	326	Target Neighborhood Hits	964	Shared Neighborhood Hits	97
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

GOGA4_HUMAN
NC score	0.134404 (rank : 138)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	326	Target Neighborhood Hits	2034	Shared Neighborhood Hits	191
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

SRC_MOUSE
NC score	0.134396 (rank : 139)	θ value	1.06291 (rank : 173)
Query Neighborhood Hits	326	Target Neighborhood Hits	1033	Shared Neighborhood Hits	99
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRC_HUMAN
NC score	0.134352 (rank : 140)	θ value	1.06291 (rank : 172)
Query Neighborhood Hits	326	Target Neighborhood Hits	1058	Shared Neighborhood Hits	99
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

ITSN2_MOUSE
NC score	0.134217 (rank : 141)	θ value	0.47712 (rank : 131)
Query Neighborhood Hits	326	Target Neighborhood Hits	1371	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

SMC2_MOUSE
NC score	0.134128 (rank : 142)	θ value	0.0431538 (rank : 68)
Query Neighborhood Hits	326	Target Neighborhood Hits	1131	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

FYN_MOUSE
NC score	0.133943 (rank : 143)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	326	Target Neighborhood Hits	1073	Shared Neighborhood Hits	96
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

CYLC1_HUMAN
NC score	0.133771 (rank : 144)	θ value	0.21417 (rank : 104)
Query Neighborhood Hits	326	Target Neighborhood Hits	408	Shared Neighborhood Hits	66
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

INCE_MOUSE
NC score	0.133573 (rank : 145)	θ value	0.279714 (rank : 117)
Query Neighborhood Hits	326	Target Neighborhood Hits	903	Shared Neighborhood Hits	111
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

CALD1_HUMAN
NC score	0.133250 (rank : 146)	θ value	0.365318 (rank : 118)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	133
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

ITSN1_HUMAN
NC score	0.132946 (rank : 147)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	326	Target Neighborhood Hits	1757	Shared Neighborhood Hits	203
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

RB6I2_HUMAN
NC score	0.132346 (rank : 148)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	326	Target Neighborhood Hits	1584	Shared Neighborhood Hits	174
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CCD41_HUMAN
NC score	0.132174 (rank : 149)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	326	Target Neighborhood Hits	1139	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

K0555_HUMAN
NC score	0.132124 (rank : 150)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	326	Target Neighborhood Hits	880	Shared Neighborhood Hits	132
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

SM1L2_HUMAN
NC score	0.131820 (rank : 151)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	326	Target Neighborhood Hits	1019	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

CCD11_HUMAN
NC score	0.131707 (rank : 152)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	326	Target Neighborhood Hits	822	Shared Neighborhood Hits	133
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CP250_HUMAN
NC score	0.131678 (rank : 153)	θ value	4.03905 (rank : 241)
Query Neighborhood Hits	326	Target Neighborhood Hits	1805	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

RENT2_HUMAN
NC score	0.130575 (rank : 154)	θ value	0.163984 (rank : 99)
Query Neighborhood Hits	326	Target Neighborhood Hits	618	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

YES_HUMAN
NC score	0.130505 (rank : 155)	θ value	θ > 10 (rank : 1222)
Query Neighborhood Hits	326	Target Neighborhood Hits	1059	Shared Neighborhood Hits	99
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

TXND2_MOUSE
NC score	0.130462 (rank : 156)	θ value	θ > 10 (rank : 1193)
Query Neighborhood Hits	326	Target Neighborhood Hits	828	Shared Neighborhood Hits	129
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

YES_MOUSE
NC score	0.130173 (rank : 157)	θ value	θ > 10 (rank : 1223)
Query Neighborhood Hits	326	Target Neighborhood Hits	1052	Shared Neighborhood Hits	99
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

HCK_HUMAN
NC score	0.130167 (rank : 158)	θ value	1.06291 (rank : 163)
Query Neighborhood Hits	326	Target Neighborhood Hits	1035	Shared Neighborhood Hits	100
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

LCK_HUMAN
NC score	0.129985 (rank : 159)	θ value	0.163984 (rank : 97)
Query Neighborhood Hits	326	Target Neighborhood Hits	987	Shared Neighborhood Hits	93
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

INCE_HUMAN
NC score	0.129647 (rank : 160)	θ value	1.06291 (rank : 164)
Query Neighborhood Hits	326	Target Neighborhood Hits	978	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

PIBF1_HUMAN
NC score	0.129208 (rank : 161)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	326	Target Neighborhood Hits	1041	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

LCK_MOUSE
NC score	0.129156 (rank : 162)	θ value	0.21417 (rank : 107)
Query Neighborhood Hits	326	Target Neighborhood Hits	981	Shared Neighborhood Hits	95
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

TPR_HUMAN
NC score	0.128811 (rank : 163)	θ value	θ > 10 (rank : 1170)
Query Neighborhood Hits	326	Target Neighborhood Hits	1921	Shared Neighborhood Hits	174
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CCD55_HUMAN
NC score	0.128509 (rank : 164)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	326	Target Neighborhood Hits	513	Shared Neighborhood Hits	110
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

PEPL_MOUSE
NC score	0.128496 (rank : 165)	θ value	0.813845 (rank : 156)
Query Neighborhood Hits	326	Target Neighborhood Hits	1105	Shared Neighborhood Hits	141
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

BLK_MOUSE
NC score	0.128129 (rank : 166)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	326	Target Neighborhood Hits	992	Shared Neighborhood Hits	99
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

ZC313_HUMAN
NC score	0.128122 (rank : 167)	θ value	6.88961 (rank : 304)
Query Neighborhood Hits	326	Target Neighborhood Hits	772	Shared Neighborhood Hits	131
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

REST_HUMAN
NC score	0.128119 (rank : 168)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	326	Target Neighborhood Hits	1605	Shared Neighborhood Hits	173
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

TAF3_MOUSE
NC score	0.128072 (rank : 169)	θ value	0.0563607 (rank : 77)
Query Neighborhood Hits	326	Target Neighborhood Hits	463	Shared Neighborhood Hits	76
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CCD91_HUMAN
NC score	0.128069 (rank : 170)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	326	Target Neighborhood Hits	868	Shared Neighborhood Hits	148
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

RIMB1_MOUSE
NC score	0.127756 (rank : 171)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	326	Target Neighborhood Hits	1376	Shared Neighborhood Hits	163
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

LEO1_HUMAN
NC score	0.127754 (rank : 172)	θ value	0.163984 (rank : 98)
Query Neighborhood Hits	326	Target Neighborhood Hits	958	Shared Neighborhood Hits	116
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MPP8_HUMAN
NC score	0.127616 (rank : 173)	θ value	0.21417 (rank : 109)
Query Neighborhood Hits	326	Target Neighborhood Hits	948	Shared Neighborhood Hits	153
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

GOGA4_MOUSE
NC score	0.127609 (rank : 174)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	326	Target Neighborhood Hits	1939	Shared Neighborhood Hits	187
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_MOUSE
NC score	0.127595 (rank : 175)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	326	Target Neighborhood Hits	1434	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CI093_HUMAN
NC score	0.127443 (rank : 176)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	326	Target Neighborhood Hits	1088	Shared Neighborhood Hits	153
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

IFT81_MOUSE
NC score	0.127309 (rank : 177)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	136
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

ZN291_HUMAN
NC score	0.127261 (rank : 178)	θ value	0.125558 (rank : 92)
Query Neighborhood Hits	326	Target Neighborhood Hits	647	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

NPBL_MOUSE
NC score	0.127253 (rank : 179)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	326	Target Neighborhood Hits	1041	Shared Neighborhood Hits	132
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TRIPB_HUMAN
NC score	0.127210 (rank : 180)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	326	Target Neighborhood Hits	1587	Shared Neighborhood Hits	158
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

RAD50_MOUSE
NC score	0.127057 (rank : 181)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	326	Target Neighborhood Hits	1366	Shared Neighborhood Hits	156
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RB6I2_MOUSE
NC score	0.126966 (rank : 182)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	326	Target Neighborhood Hits	1433	Shared Neighborhood Hits	167
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

MATK_HUMAN
NC score	0.126688 (rank : 183)	θ value	4.03905 (rank : 252)
Query Neighborhood Hits	326	Target Neighborhood Hits	954	Shared Neighborhood Hits	99
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MAP1B_MOUSE
NC score	0.125750 (rank : 184)	θ value	1.06291 (rank : 166)
Query Neighborhood Hits	326	Target Neighborhood Hits	977	Shared Neighborhood Hits	97
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

HCK_MOUSE
NC score	0.125744 (rank : 185)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	326	Target Neighborhood Hits	1029	Shared Neighborhood Hits	95
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

MATK_MOUSE
NC score	0.125739 (rank : 186)	θ value	5.27518 (rank : 270)
Query Neighborhood Hits	326	Target Neighborhood Hits	952	Shared Neighborhood Hits	99
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

DESP_HUMAN
NC score	0.125585 (rank : 187)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	326	Target Neighborhood Hits	1470	Shared Neighborhood Hits	158
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

CENPF_HUMAN
NC score	0.125498 (rank : 188)	θ value	4.03905 (rank : 239)
Query Neighborhood Hits	326	Target Neighborhood Hits	1932	Shared Neighborhood Hits	182
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

SYCP1_HUMAN
NC score	0.125374 (rank : 189)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	326	Target Neighborhood Hits	1313	Shared Neighborhood Hits	162
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

RIMB1_HUMAN
NC score	0.125346 (rank : 190)	θ value	2.36792 (rank : 216)
Query Neighborhood Hits	326	Target Neighborhood Hits	1479	Shared Neighborhood Hits	163
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CCD19_HUMAN
NC score	0.124936 (rank : 191)	θ value	1.81305 (rank : 193)
Query Neighborhood Hits	326	Target Neighborhood Hits	639	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CK5P2_MOUSE
NC score	0.124925 (rank : 192)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	326	Target Neighborhood Hits	1151	Shared Neighborhood Hits	147
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CCD21_MOUSE
NC score	0.124773 (rank : 193)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	326	Target Neighborhood Hits	1135	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CING_MOUSE
NC score	0.124764 (rank : 194)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	326	Target Neighborhood Hits	1432	Shared Neighborhood Hits	167
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

RAD50_HUMAN
NC score	0.124648 (rank : 195)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	326	Target Neighborhood Hits	1317	Shared Neighborhood Hits	150
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

STMN1_HUMAN
NC score	0.124460 (rank : 196)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	326	Target Neighborhood Hits	554	Shared Neighborhood Hits	133
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

ZAP70_MOUSE
NC score	0.124398 (rank : 197)	θ value	0.0431538 (rank : 70)
Query Neighborhood Hits	326	Target Neighborhood Hits	905	Shared Neighborhood Hits	97
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

SMC3_HUMAN
NC score	0.124364 (rank : 198)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	326	Target Neighborhood Hits	1186	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

CT2NL_MOUSE
NC score	0.124364 (rank : 199)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	326	Target Neighborhood Hits	902	Shared Neighborhood Hits	154
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

SMC3_MOUSE
NC score	0.124310 (rank : 200)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	326	Target Neighborhood Hits	1187	Shared Neighborhood Hits	157
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

STMN1_MOUSE
NC score	0.124294 (rank : 201)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	326	Target Neighborhood Hits	560	Shared Neighborhood Hits	132
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

BRE1A_HUMAN
NC score	0.124243 (rank : 202)	θ value	0.000786445 (rank : 24)
Query Neighborhood Hits	326	Target Neighborhood Hits	1071	Shared Neighborhood Hits	114
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CCD21_HUMAN
NC score	0.123767 (rank : 203)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	326	Target Neighborhood Hits	1228	Shared Neighborhood Hits	162
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

PLCB4_HUMAN
NC score	0.123649 (rank : 204)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	326	Target Neighborhood Hits	658	Shared Neighborhood Hits	129
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

SDCG8_HUMAN
NC score	0.123450 (rank : 205)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	326	Target Neighborhood Hits	1002	Shared Neighborhood Hits	147
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

ZAP70_HUMAN
NC score	0.123313 (rank : 206)	θ value	0.0330416 (rank : 64)
Query Neighborhood Hits	326	Target Neighborhood Hits	893	Shared Neighborhood Hits	95
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

BRE1B_HUMAN
NC score	0.122906 (rank : 207)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	326	Target Neighborhood Hits	1040	Shared Neighborhood Hits	128
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CNTRB_MOUSE
NC score	0.122787 (rank : 208)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	326	Target Neighborhood Hits	1029	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

OPTN_MOUSE
NC score	0.122477 (rank : 209)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	326	Target Neighborhood Hits	1120	Shared Neighborhood Hits	150
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CENPE_HUMAN
NC score	0.122375 (rank : 210)	θ value	8.99809 (rank : 310)
Query Neighborhood Hits	326	Target Neighborhood Hits	2060	Shared Neighborhood Hits	186
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

EEA1_HUMAN
NC score	0.122115 (rank : 211)	θ value	0.163984 (rank : 96)
Query Neighborhood Hits	326	Target Neighborhood Hits	1796	Shared Neighborhood Hits	168
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

LYN_MOUSE
NC score	0.122050 (rank : 212)	θ value	6.88961 (rank : 294)
Query Neighborhood Hits	326	Target Neighborhood Hits	1023	Shared Neighborhood Hits	98
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

CENPJ_HUMAN
NC score	0.121821 (rank : 213)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	326	Target Neighborhood Hits	721	Shared Neighborhood Hits	140
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

LYN_HUMAN
NC score	0.121572 (rank : 214)	θ value	4.03905 (rank : 251)
Query Neighborhood Hits	326	Target Neighborhood Hits	1022	Shared Neighborhood Hits	97
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

EEA1_MOUSE
NC score	0.121366 (rank : 215)	θ value	3.0926 (rank : 227)
Query Neighborhood Hits	326	Target Neighborhood Hits	1637	Shared Neighborhood Hits	166
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

BRE1A_MOUSE
NC score	0.121217 (rank : 216)	θ value	0.47712 (rank : 126)
Query Neighborhood Hits	326	Target Neighborhood Hits	1025	Shared Neighborhood Hits	110
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

KIF4A_HUMAN
NC score	0.120811 (rank : 217)	θ value	0.0330416 (rank : 60)
Query Neighborhood Hits	326	Target Neighborhood Hits	1159	Shared Neighborhood Hits	160
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

REST_MOUSE
NC score	0.120597 (rank : 218)	θ value	0.47712 (rank : 133)
Query Neighborhood Hits	326	Target Neighborhood Hits	1506	Shared Neighborhood Hits	161
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

GAS8_HUMAN
NC score	0.120443 (rank : 219)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	326	Target Neighborhood Hits	819	Shared Neighborhood Hits	125
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

CISH_MOUSE
NC score	0.120262 (rank : 220)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	326	Target Neighborhood Hits	94	Shared Neighborhood Hits	55
SwissProt Accessions	Q62225, Q3TC70	Gene names	Cish, Cis
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS).

ATRX_HUMAN
NC score	0.120176 (rank : 221)	θ value	0.0736092 (rank : 78)
Query Neighborhood Hits	326	Target Neighborhood Hits	842	Shared Neighborhood Hits	117
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CISH_HUMAN
NC score	0.120067 (rank : 222)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	326	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NSE2, Q9NS38, Q9Y5R1	Gene names	CISH, G18
Domain Architecture
Description	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS) (Protein G18).

CYLC2_HUMAN
NC score	0.119998 (rank : 223)	θ value	0.163984 (rank : 94)
Query Neighborhood Hits	326	Target Neighborhood Hits	223	Shared Neighborhood Hits	36
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

AZI1_MOUSE
NC score	0.119790 (rank : 224)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	326	Target Neighborhood Hits	990	Shared Neighborhood Hits	121
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CCD91_MOUSE
NC score	0.119693 (rank : 225)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	326	Target Neighborhood Hits	699	Shared Neighborhood Hits	116
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

ITSN2_HUMAN
NC score	0.119605 (rank : 226)	θ value	0.365318 (rank : 119)
Query Neighborhood Hits	326	Target Neighborhood Hits	1173	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

CP135_MOUSE
NC score	0.119353 (rank : 227)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	326	Target Neighborhood Hits	1278	Shared Neighborhood Hits	156
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TRDN_HUMAN
NC score	0.119254 (rank : 228)	θ value	0.0330416 (rank : 63)
Query Neighborhood Hits	326	Target Neighborhood Hits	542	Shared Neighborhood Hits	71
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

BTK_HUMAN
NC score	0.118999 (rank : 229)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	326	Target Neighborhood Hits	1026	Shared Neighborhood Hits	90
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

LIPA1_HUMAN
NC score	0.118980 (rank : 230)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	326	Target Neighborhood Hits	1294	Shared Neighborhood Hits	169
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

PCNT_HUMAN
NC score	0.118903 (rank : 231)	θ value	6.88961 (rank : 296)
Query Neighborhood Hits	326	Target Neighborhood Hits	1551	Shared Neighborhood Hits	159
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RABE1_MOUSE
NC score	0.118882 (rank : 232)	θ value	2.36792 (rank : 214)
Query Neighborhood Hits	326	Target Neighborhood Hits	1105	Shared Neighborhood Hits	139
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

BPAEA_MOUSE
NC score	0.118867 (rank : 233)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	326	Target Neighborhood Hits	1480	Shared Neighborhood Hits	170
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TXK_MOUSE
NC score	0.118861 (rank : 234)	θ value	θ > 10 (rank : 1185)
Query Neighborhood Hits	326	Target Neighborhood Hits	980	Shared Neighborhood Hits	94
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

GOGA6_HUMAN
NC score	0.118844 (rank : 235)	θ value	3.0926 (rank : 229)
Query Neighborhood Hits	326	Target Neighborhood Hits	1007	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

TMF1_HUMAN
NC score	0.118662 (rank : 236)	θ value	0.62314 (rank : 146)
Query Neighborhood Hits	326	Target Neighborhood Hits	987	Shared Neighborhood Hits	121
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

NEBL_HUMAN
NC score	0.118431 (rank : 237)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	326	Target Neighborhood Hits	457	Shared Neighborhood Hits	117
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

GCC2_MOUSE
NC score	0.118392 (rank : 238)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	326	Target Neighborhood Hits	1619	Shared Neighborhood Hits	160
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

BTK_MOUSE
NC score	0.118384 (rank : 239)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	326	Target Neighborhood Hits	1017	Shared Neighborhood Hits	90
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CING_HUMAN
NC score	0.118383 (rank : 240)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	326	Target Neighborhood Hits	1275	Shared Neighborhood Hits	153
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

NDE1_HUMAN
NC score	0.118336 (rank : 241)	θ value	0.47712 (rank : 132)
Query Neighborhood Hits	326	Target Neighborhood Hits	823	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

CCD39_MOUSE
NC score	0.117998 (rank : 242)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	326	Target Neighborhood Hits	1026	Shared Neighborhood Hits	135
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

MACOI_HUMAN
NC score	0.117933 (rank : 243)	θ value	0.125558 (rank : 89)
Query Neighborhood Hits	326	Target Neighborhood Hits	650	Shared Neighborhood Hits	95
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

AKAP9_HUMAN
NC score	0.117713 (rank : 244)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	326	Target Neighborhood Hits	1710	Shared Neighborhood Hits	159
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CF060_HUMAN
NC score	0.117650 (rank : 245)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	326	Target Neighborhood Hits	1270	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CROCC_MOUSE
NC score	0.117635 (rank : 246)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	326	Target Neighborhood Hits	1460	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GRAP1_MOUSE
NC score	0.117560 (rank : 247)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	326	Target Neighborhood Hits	1234	Shared Neighborhood Hits	154
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

TXK_HUMAN
NC score	0.117467 (rank : 248)	θ value	θ > 10 (rank : 1184)
Query Neighborhood Hits	326	Target Neighborhood Hits	971	Shared Neighborhood Hits	91
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

PRP40_HUMAN
NC score	0.117433 (rank : 249)	θ value	1.38821 (rank : 186)
Query Neighborhood Hits	326	Target Neighborhood Hits	442	Shared Neighborhood Hits	92
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
NC score	0.117308 (rank : 250)	θ value	5.27518 (rank : 276)
Query Neighborhood Hits	326	Target Neighborhood Hits	447	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RRBP1_HUMAN
NC score	0.117222 (rank : 251)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	326	Target Neighborhood Hits	1306	Shared Neighborhood Hits	143
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

CE152_HUMAN
NC score	0.117011 (rank : 252)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	326	Target Neighborhood Hits	976	Shared Neighborhood Hits	124
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

KMHN1_HUMAN
NC score	0.116850 (rank : 253)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	326	Target Neighborhood Hits	950	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KTN1_MOUSE
NC score	0.116673 (rank : 254)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	326	Target Neighborhood Hits	1324	Shared Neighborhood Hits	155
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

PEPL_HUMAN
NC score	0.116600 (rank : 255)	θ value	5.27518 (rank : 273)
Query Neighborhood Hits	326	Target Neighborhood Hits	1141	Shared Neighborhood Hits	141
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

TAF3_HUMAN
NC score	0.116492 (rank : 256)	θ value	0.47712 (rank : 135)
Query Neighborhood Hits	326	Target Neighborhood Hits	568	Shared Neighborhood Hits	78
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CP250_MOUSE
NC score	0.116445 (rank : 257)	θ value	0.47712 (rank : 128)
Query Neighborhood Hits	326	Target Neighborhood Hits	1583	Shared Neighborhood Hits	158
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

TAXB1_HUMAN
NC score	0.116439 (rank : 258)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	326	Target Neighborhood Hits	829	Shared Neighborhood Hits	127
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

BLK_HUMAN
NC score	0.116391 (rank : 259)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	326	Target Neighborhood Hits	994	Shared Neighborhood Hits	91
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

XE7_HUMAN
NC score	0.116131 (rank : 260)	θ value	θ > 10 (rank : 1221)
Query Neighborhood Hits	326	Target Neighborhood Hits	738	Shared Neighborhood Hits	105
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

RBM25_HUMAN
NC score	0.115911 (rank : 261)	θ value	6.88961 (rank : 299)
Query Neighborhood Hits	326	Target Neighborhood Hits	682	Shared Neighborhood Hits	93
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

ACINU_MOUSE
NC score	0.115746 (rank : 262)	θ value	1.38821 (rank : 177)
Query Neighborhood Hits	326	Target Neighborhood Hits	712	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CP135_HUMAN
NC score	0.115711 (rank : 263)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	326	Target Neighborhood Hits	1290	Shared Neighborhood Hits	159
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

NAF1_HUMAN
NC score	0.115422 (rank : 264)	θ value	4.03905 (rank : 255)
Query Neighborhood Hits	326	Target Neighborhood Hits	937	Shared Neighborhood Hits	132
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

RABE1_HUMAN
NC score	0.114907 (rank : 265)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	326	Target Neighborhood Hits	1104	Shared Neighborhood Hits	128
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

CCD45_HUMAN
NC score	0.114505 (rank : 266)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	326	Target Neighborhood Hits	525	Shared Neighborhood Hits	116
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

TR150_MOUSE
NC score	0.114497 (rank : 267)	θ value	θ > 10 (rank : 1172)
Query Neighborhood Hits	326	Target Neighborhood Hits	468	Shared Neighborhood Hits	113
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ITK_MOUSE
NC score	0.114490 (rank : 268)	θ value	4.03905 (rank : 247)
Query Neighborhood Hits	326	Target Neighborhood Hits	985	Shared Neighborhood Hits	93
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

FLIP1_HUMAN
NC score	0.113885 (rank : 269)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	326	Target Neighborhood Hits	1405	Shared Neighborhood Hits	157
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MACOI_MOUSE
NC score	0.113826 (rank : 270)	θ value	1.06291 (rank : 165)
Query Neighborhood Hits	326	Target Neighborhood Hits	620	Shared Neighborhood Hits	93
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

HOME2_MOUSE
NC score	0.113674 (rank : 271)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	326	Target Neighborhood Hits	882	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

BRE1B_MOUSE
NC score	0.113615 (rank : 272)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	326	Target Neighborhood Hits	970	Shared Neighborhood Hits	115
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

GOGA5_HUMAN
NC score	0.113489 (rank : 273)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	326	Target Neighborhood Hits	1168	Shared Neighborhood Hits	147
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

SAS6_MOUSE
NC score	0.113387 (rank : 274)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	326	Target Neighborhood Hits	931	Shared Neighborhood Hits	125
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

CASP_HUMAN
NC score	0.113307 (rank : 275)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	326	Target Neighborhood Hits	1131	Shared Neighborhood Hits	146
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

SDCG8_MOUSE
NC score	0.113285 (rank : 276)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	326	Target Neighborhood Hits	886	Shared Neighborhood Hits	142
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

FES_HUMAN
NC score	0.113269 (rank : 277)	θ value	0.0961366 (rank : 81)
Query Neighborhood Hits	326	Target Neighborhood Hits	978	Shared Neighborhood Hits	99
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

CYLN2_HUMAN
NC score	0.113187 (rank : 278)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	326	Target Neighborhood Hits	1004	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

IFT81_HUMAN
NC score	0.113151 (rank : 279)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	326	Target Neighborhood Hits	893	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IWS1_HUMAN
NC score	0.113099 (rank : 280)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	326	Target Neighborhood Hits	1241	Shared Neighborhood Hits	124
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CEP35_HUMAN
NC score	0.112982 (rank : 281)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	326	Target Neighborhood Hits	811	Shared Neighborhood Hits	124
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

RBP24_HUMAN
NC score	0.112940 (rank : 282)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	326	Target Neighborhood Hits	1559	Shared Neighborhood Hits	146
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GOGA3_MOUSE
NC score	0.112830 (rank : 283)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	326	Target Neighborhood Hits	1437	Shared Neighborhood Hits	149
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

SWP70_MOUSE
NC score	0.112740 (rank : 284)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	326	Target Neighborhood Hits	1097	Shared Neighborhood Hits	138
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

MFAP1_HUMAN
NC score	0.112736 (rank : 285)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	326	Target Neighborhood Hits	321	Shared Neighborhood Hits	64
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

OPTN_HUMAN
NC score	0.112676 (rank : 286)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	326	Target Neighborhood Hits	827	Shared Neighborhood Hits	137
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

CASP_MOUSE
NC score	0.112464 (rank : 287)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	326	Target Neighborhood Hits	1152	Shared Neighborhood Hits	145
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

MYH11_HUMAN
NC score	0.112390 (rank : 288)	θ value	0.813845 (rank : 153)
Query Neighborhood Hits	326	Target Neighborhood Hits	1806	Shared Neighborhood Hits	182
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
NC score	0.112326 (rank : 289)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	326	Target Neighborhood Hits	1829	Shared Neighborhood Hits	182
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

STK10_MOUSE
NC score	0.112273 (rank : 290)	θ value	0.0330416 (rank : 62)
Query Neighborhood Hits	326	Target Neighborhood Hits	2132	Shared Neighborhood Hits	214
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

CDC37_HUMAN
NC score	0.112207 (rank : 291)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	326	Target Neighborhood Hits	506	Shared Neighborhood Hits	114
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

GCC2_HUMAN
NC score	0.112155 (rank : 292)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	326	Target Neighborhood Hits	1558	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

MYH11_MOUSE
NC score	0.111961 (rank : 293)	θ value	0.813845 (rank : 154)
Query Neighborhood Hits	326	Target Neighborhood Hits	1777	Shared Neighborhood Hits	179
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

HMMR_MOUSE
NC score	0.111917 (rank : 294)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	326	Target Neighborhood Hits	1178	Shared Neighborhood Hits	137
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CIP4_HUMAN
NC score	0.111808 (rank : 295)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	326	Target Neighborhood Hits	374	Shared Neighborhood Hits	83
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

GAS8_MOUSE
NC score	0.111801 (rank : 296)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	326	Target Neighborhood Hits	622	Shared Neighborhood Hits	112
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

ITK_HUMAN
NC score	0.111722 (rank : 297)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	326	Target Neighborhood Hits	1016	Shared Neighborhood Hits	95
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

HIP1R_MOUSE
NC score	0.111592 (rank : 298)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	137
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

GOGA1_HUMAN
NC score	0.111579 (rank : 299)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	326	Target Neighborhood Hits	1222	Shared Neighborhood Hits	132
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

BMX_HUMAN
NC score	0.111252 (rank : 300)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	326	Target Neighborhood Hits	942	Shared Neighborhood Hits	89
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

SM1L2_MOUSE
NC score	0.111184 (rank : 301)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	326	Target Neighborhood Hits	918	Shared Neighborhood Hits	121
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

KMHN1_MOUSE
NC score	0.111015 (rank : 302)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	326	Target Neighborhood Hits	949	Shared Neighborhood Hits	135
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

CHIN_MOUSE
NC score	0.110980 (rank : 303)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	326	Target Neighborhood Hits	229	Shared Neighborhood Hits	77
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

NASP_HUMAN
NC score	0.110709 (rank : 304)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	326	Target Neighborhood Hits	709	Shared Neighborhood Hits	115
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NUMA1_HUMAN
NC score	0.110587 (rank : 305)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	326	Target Neighborhood Hits	1523	Shared Neighborhood Hits	149
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PININ_HUMAN
NC score	0.110423 (rank : 306)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	326	Target Neighborhood Hits	753	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PCNT_MOUSE
NC score	0.110166 (rank : 307)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	326	Target Neighborhood Hits	1207	Shared Neighborhood Hits	127
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

MFAP1_MOUSE
NC score	0.110130 (rank : 308)	θ value	0.365318 (rank : 120)
Query Neighborhood Hits	326	Target Neighborhood Hits	353	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

LCP2_MOUSE
NC score	0.109995 (rank : 309)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	326	Target Neighborhood Hits	177	Shared Neighborhood Hits	50
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

CCD96_HUMAN
NC score	0.109974 (rank : 310)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	326	Target Neighborhood Hits	595	Shared Neighborhood Hits	91
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

NIN_MOUSE
NC score	0.109890 (rank : 311)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	326	Target Neighborhood Hits	1376	Shared Neighborhood Hits	137
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

BMX_MOUSE
NC score	0.109846 (rank : 312)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	326	Target Neighborhood Hits	912	Shared Neighborhood Hits	87
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

PHLB2_MOUSE
NC score	0.109751 (rank : 313)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	326	Target Neighborhood Hits	1016	Shared Neighborhood Hits	142
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

EVPL_HUMAN
NC score	0.109563 (rank : 314)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	326	Target Neighborhood Hits	895	Shared Neighborhood Hits	121
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

MYH9_HUMAN
NC score	0.109498 (rank : 315)	θ value	0.62314 (rank : 139)
Query Neighborhood Hits	326	Target Neighborhood Hits	1762	Shared Neighborhood Hits	172
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

LRC45_MOUSE
NC score	0.109497 (rank : 316)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LIPA2_MOUSE
NC score	0.109451 (rank : 317)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	326	Target Neighborhood Hits	1282	Shared Neighborhood Hits	155
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LEO1_MOUSE
NC score	0.109398 (rank : 318)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	326	Target Neighborhood Hits	946	Shared Neighborhood Hits	113
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

HIP1_HUMAN
NC score	0.109383 (rank : 319)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	326	Target Neighborhood Hits	1016	Shared Neighborhood Hits	135
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

NIN_HUMAN
NC score	0.109121 (rank : 320)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	326	Target Neighborhood Hits	1416	Shared Neighborhood Hits	137
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

TEC_HUMAN
NC score	0.109026 (rank : 321)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	326	Target Neighborhood Hits	1006	Shared Neighborhood Hits	86
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

BICD1_MOUSE
NC score	0.108936 (rank : 322)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	326	Target Neighborhood Hits	837	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

EVPL_MOUSE
NC score	0.108481 (rank : 323)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	326	Target Neighborhood Hits	952	Shared Neighborhood Hits	123
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

CF152_HUMAN
NC score	0.108399 (rank : 324)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	326	Target Neighborhood Hits	704	Shared Neighborhood Hits	123
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CROP_MOUSE
NC score	0.108387 (rank : 325)	θ value	0.47712 (rank : 129)
Query Neighborhood Hits	326	Target Neighborhood Hits	403	Shared Neighborhood Hits	69
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

GOGA1_MOUSE
NC score	0.108323 (rank : 326)	θ value	8.99809 (rank : 317)
Query Neighborhood Hits	326	Target Neighborhood Hits	994	Shared Neighborhood Hits	118
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

PININ_MOUSE
NC score	0.108180 (rank : 327)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	326	Target Neighborhood Hits	777	Shared Neighborhood Hits	127
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

CHIN_HUMAN
NC score	0.108037 (rank : 328)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

ATRX_MOUSE
NC score	0.107921 (rank : 329)	θ value	0.163984 (rank : 93)
Query Neighborhood Hits	326	Target Neighborhood Hits	682	Shared Neighborhood Hits	99
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

UACA_MOUSE
NC score	0.107875 (rank : 330)	θ value	θ > 10 (rank : 1200)
Query Neighborhood Hits	326	Target Neighborhood Hits	1620	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

CJ118_MOUSE
NC score	0.107719 (rank : 331)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	326	Target Neighborhood Hits	1132	Shared Neighborhood Hits	143
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

MYH10_MOUSE
NC score	0.107477 (rank : 332)	θ value	0.0961366 (rank : 85)
Query Neighborhood Hits	326	Target Neighborhood Hits	1612	Shared Neighborhood Hits	151
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ERC2_HUMAN
NC score	0.107387 (rank : 333)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	326	Target Neighborhood Hits	1156	Shared Neighborhood Hits	140
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CEP63_HUMAN
NC score	0.107176 (rank : 334)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	326	Target Neighborhood Hits	1005	Shared Neighborhood Hits	120
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CCD39_HUMAN
NC score	0.106933 (rank : 335)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	326	Target Neighborhood Hits	868	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD45_MOUSE
NC score	0.106763 (rank : 336)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	326	Target Neighborhood Hits	663	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

ERC2_MOUSE
NC score	0.106734 (rank : 337)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	326	Target Neighborhood Hits	1166	Shared Neighborhood Hits	143
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

MD1L1_MOUSE
NC score	0.106427 (rank : 338)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	326	Target Neighborhood Hits	1001	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MYH10_HUMAN
NC score	0.106385 (rank : 339)	θ value	0.125558 (rank : 90)
Query Neighborhood Hits	326	Target Neighborhood Hits	1620	Shared Neighborhood Hits	151
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CCHCR_MOUSE
NC score	0.106366 (rank : 340)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	326	Target Neighborhood Hits	932	Shared Neighborhood Hits	139
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CN145_MOUSE
NC score	0.106211 (rank : 341)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	326	Target Neighborhood Hits	916	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

FES_MOUSE
NC score	0.106015 (rank : 342)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	326	Target Neighborhood Hits	980	Shared Neighborhood Hits	91
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

AZI1_HUMAN
NC score	0.105874 (rank : 343)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	326	Target Neighborhood Hits	1000	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CF010_HUMAN
NC score	0.105789 (rank : 344)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	326	Target Neighborhood Hits	329	Shared Neighborhood Hits	84
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CCD55_MOUSE
NC score	0.105590 (rank : 345)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	326	Target Neighborhood Hits	519	Shared Neighborhood Hits	99
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

TEC_MOUSE
NC score	0.105465 (rank : 346)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	326	Target Neighborhood Hits	1006	Shared Neighborhood Hits	82
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TAXB1_MOUSE
NC score	0.105192 (rank : 347)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	326	Target Neighborhood Hits	886	Shared Neighborhood Hits	117
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

IFT74_HUMAN
NC score	0.105143 (rank : 348)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	326	Target Neighborhood Hits	949	Shared Neighborhood Hits	121
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

NAF1_MOUSE
NC score	0.105123 (rank : 349)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	326	Target Neighborhood Hits	852	Shared Neighborhood Hits	119
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

GOGA3_HUMAN
NC score	0.105118 (rank : 350)	θ value	6.88961 (rank : 292)
Query Neighborhood Hits	326	Target Neighborhood Hits	1317	Shared Neighborhood Hits	133
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

BICD1_HUMAN
NC score	0.105043 (rank : 351)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	326	Target Neighborhood Hits	844	Shared Neighborhood Hits	115
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

SOCS3_HUMAN
NC score	0.104998 (rank : 352)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	326	Target Neighborhood Hits	77	Shared Neighborhood Hits	45
SwissProt Accessions	O14543, O14509	Gene names	SOCS3, CIS3, SSI3
Domain Architecture
Description	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3).

CYLN2_MOUSE
NC score	0.104948 (rank : 353)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	326	Target Neighborhood Hits	1002	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

ANR26_MOUSE
NC score	0.104851 (rank : 354)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	326	Target Neighborhood Hits	1554	Shared Neighborhood Hits	159
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

TACC2_HUMAN
NC score	0.104815 (rank : 355)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	326	Target Neighborhood Hits	856	Shared Neighborhood Hits	119
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

SFR17_HUMAN
NC score	0.104672 (rank : 356)	θ value	0.125558 (rank : 91)
Query Neighborhood Hits	326	Target Neighborhood Hits	325	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

PHLB2_HUMAN
NC score	0.104368 (rank : 357)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	326	Target Neighborhood Hits	964	Shared Neighborhood Hits	135
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHF20_MOUSE
NC score	0.104259 (rank : 358)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	326	Target Neighborhood Hits	513	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

CUTL1_HUMAN
NC score	0.104256 (rank : 359)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	326	Target Neighborhood Hits	1574	Shared Neighborhood Hits	154
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CHIO_HUMAN
NC score	0.103956 (rank : 360)	θ value	2.36792 (rank : 209)
Query Neighborhood Hits	326	Target Neighborhood Hits	220	Shared Neighborhood Hits	73
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

SOCS3_MOUSE
NC score	0.103938 (rank : 361)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	326	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	O35718, P97803, Q3U7X5	Gene names	Socs3, Cis3, Cish3
Domain Architecture
Description	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (Protein EF-10).

MYH3_HUMAN
NC score	0.103926 (rank : 362)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	326	Target Neighborhood Hits	1660	Shared Neighborhood Hits	165
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

KIF4A_MOUSE
NC score	0.103536 (rank : 363)	θ value	0.0563607 (rank : 73)
Query Neighborhood Hits	326	Target Neighborhood Hits	1033	Shared Neighborhood Hits	140
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

FLIP1_MOUSE
NC score	0.103441 (rank : 364)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	326	Target Neighborhood Hits	1176	Shared Neighborhood Hits	134
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

SDPR_MOUSE
NC score	0.103417 (rank : 365)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	326	Target Neighborhood Hits	485	Shared Neighborhood Hits	113
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

CJ068_HUMAN
NC score	0.103177 (rank : 366)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	326	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

RFC1_HUMAN
NC score	0.103156 (rank : 367)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	326	Target Neighborhood Hits	352	Shared Neighborhood Hits	75
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

CROP_HUMAN
NC score	0.103150 (rank : 368)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	326	Target Neighborhood Hits	402	Shared Neighborhood Hits	69
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

LRRF2_HUMAN
NC score	0.102952 (rank : 369)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	326	Target Neighborhood Hits	791	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

RBMX2_HUMAN
NC score	0.102916 (rank : 370)	θ value	4.92598e-06 (rank : 7)
Query Neighborhood Hits	326	Target Neighborhood Hits	351	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y388, Q5JY82, Q9Y3I8	Gene names	RBMX2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

CEP55_MOUSE
NC score	0.102859 (rank : 371)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	326	Target Neighborhood Hits	693	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

LUZP1_MOUSE
NC score	0.102659 (rank : 372)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	326	Target Neighborhood Hits	940	Shared Neighborhood Hits	141
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

KINH_HUMAN
NC score	0.102657 (rank : 373)	θ value	4.03905 (rank : 250)
Query Neighborhood Hits	326	Target Neighborhood Hits	1231	Shared Neighborhood Hits	158
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

CCD93_HUMAN
NC score	0.102635 (rank : 374)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	326	Target Neighborhood Hits	600	Shared Neighborhood Hits	103
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

AKA12_HUMAN
NC score	0.102391 (rank : 375)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	326	Target Neighborhood Hits	825	Shared Neighborhood Hits	118
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CUTL1_MOUSE
NC score	0.102248 (rank : 376)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	326	Target Neighborhood Hits	1620	Shared Neighborhood Hits	155
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

RFIP3_HUMAN
NC score	0.102241 (rank : 377)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	326	Target Neighborhood Hits	1055	Shared Neighborhood Hits	132
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

CARD9_HUMAN
NC score	0.102085 (rank : 378)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	326	Target Neighborhood Hits	602	Shared Neighborhood Hits	106
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

RUFY2_HUMAN
NC score	0.101752 (rank : 379)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	326	Target Neighborhood Hits	1208	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

WDR67_HUMAN
NC score	0.101548 (rank : 380)	θ value	θ > 10 (rank : 1220)
Query Neighborhood Hits	326	Target Neighborhood Hits	782	Shared Neighborhood Hits	111
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

NEMO_HUMAN
NC score	0.101004 (rank : 381)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	326	Target Neighborhood Hits	820	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

MYH8_HUMAN
NC score	0.100838 (rank : 382)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	326	Target Neighborhood Hits	1610	Shared Neighborhood Hits	168
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

BICD2_HUMAN
NC score	0.100832 (rank : 383)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	326	Target Neighborhood Hits	856	Shared Neighborhood Hits	115
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

MD1L1_HUMAN
NC score	0.100793 (rank : 384)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	326	Target Neighborhood Hits	893	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

CCDC6_HUMAN
NC score	0.100632 (rank : 385)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	326	Target Neighborhood Hits	723	Shared Neighborhood Hits	111
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

UACA_HUMAN
NC score	0.100478 (rank : 386)	θ value	8.99809 (rank : 326)
Query Neighborhood Hits	326	Target Neighborhood Hits	1622	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ANR26_HUMAN
NC score	0.100313 (rank : 387)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	326	Target Neighborhood Hits	1614	Shared Neighborhood Hits	163
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DNJC8_MOUSE
NC score	0.100265 (rank : 388)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	326	Target Neighborhood Hits	392	Shared Neighborhood Hits	107
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

IFT74_MOUSE
NC score	0.100052 (rank : 389)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	326	Target Neighborhood Hits	939	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

RBCC1_MOUSE
NC score	0.100003 (rank : 390)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	326	Target Neighborhood Hits	1048	Shared Neighborhood Hits	127
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

MYH13_HUMAN
NC score	0.099927 (rank : 391)	θ value	4.03905 (rank : 253)
Query Neighborhood Hits	326	Target Neighborhood Hits	1504	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

BICD2_MOUSE
NC score	0.099801 (rank : 392)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	326	Target Neighborhood Hits	864	Shared Neighborhood Hits	114
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

TUFT1_MOUSE
NC score	0.099788 (rank : 393)	θ value	θ > 10 (rank : 1183)
Query Neighborhood Hits	326	Target Neighborhood Hits	732	Shared Neighborhood Hits	112
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

NDE1_MOUSE
NC score	0.099595 (rank : 394)	θ value	3.0926 (rank : 231)
Query Neighborhood Hits	326	Target Neighborhood Hits	602	Shared Neighborhood Hits	93
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

TSC1_HUMAN
NC score	0.098901 (rank : 395)	θ value	θ > 10 (rank : 1178)
Query Neighborhood Hits	326	Target Neighborhood Hits	765	Shared Neighborhood Hits	98
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

CNTRB_HUMAN
NC score	0.098685 (rank : 396)	θ value	4.03905 (rank : 240)
Query Neighborhood Hits	326	Target Neighborhood Hits	690	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CROCC_HUMAN
NC score	0.098659 (rank : 397)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	326	Target Neighborhood Hits	1409	Shared Neighborhood Hits	133
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MY18B_HUMAN
NC score	0.098370 (rank : 398)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	326	Target Neighborhood Hits	1299	Shared Neighborhood Hits	132
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH8_MOUSE
NC score	0.097974 (rank : 399)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	326	Target Neighborhood Hits	1600	Shared Neighborhood Hits	159
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

GOGA2_MOUSE
NC score	0.097823 (rank : 400)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	326	Target Neighborhood Hits	944	Shared Neighborhood Hits	110
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

CYTSA_MOUSE
NC score	0.097765 (rank : 401)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	326	Target Neighborhood Hits	1104	Shared Neighborhood Hits	134
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

EP15R_MOUSE
NC score	0.097756 (rank : 402)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	326	Target Neighborhood Hits	1135	Shared Neighborhood Hits	145
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

HMMR_HUMAN
NC score	0.097659 (rank : 403)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	326	Target Neighborhood Hits	1082	Shared Neighborhood Hits	121
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

GCC1_MOUSE
NC score	0.097557 (rank : 404)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	326	Target Neighborhood Hits	777	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

SWP70_HUMAN
NC score	0.097549 (rank : 405)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	326	Target Neighborhood Hits	973	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

MYH14_MOUSE
NC score	0.097534 (rank : 406)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	326	Target Neighborhood Hits	1225	Shared Neighborhood Hits	123
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

RFC1_MOUSE
NC score	0.097376 (rank : 407)	θ value	0.0431538 (rank : 67)
Query Neighborhood Hits	326	Target Neighborhood Hits	290	Shared Neighborhood Hits	60
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

EP15R_HUMAN
NC score	0.097200 (rank : 408)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	326	Target Neighborhood Hits	1083	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

PLCB2_HUMAN
NC score	0.097171 (rank : 409)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	326	Target Neighborhood Hits	608	Shared Neighborhood Hits	114
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

ZWINT_MOUSE
NC score	0.097125 (rank : 410)	θ value	θ > 10 (rank : 1230)
Query Neighborhood Hits	326	Target Neighborhood Hits	497	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

CYTSA_HUMAN
NC score	0.097054 (rank : 411)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	326	Target Neighborhood Hits	1138	Shared Neighborhood Hits	131
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

ZRF1_MOUSE
NC score	0.096734 (rank : 412)	θ value	1.06291 (rank : 175)
Query Neighborhood Hits	326	Target Neighborhood Hits	414	Shared Neighborhood Hits	62
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

DNJC8_HUMAN
NC score	0.096492 (rank : 413)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	326	Target Neighborhood Hits	380	Shared Neighborhood Hits	104
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

CF152_MOUSE
NC score	0.096402 (rank : 414)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	326	Target Neighborhood Hits	597	Shared Neighborhood Hits	100
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

TENS1_HUMAN
NC score	0.096381 (rank : 415)	θ value	4.03905 (rank : 259)
Query Neighborhood Hits	326	Target Neighborhood Hits	400	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

MYH6_HUMAN
NC score	0.096342 (rank : 416)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	326	Target Neighborhood Hits	1426	Shared Neighborhood Hits	142
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NTBP1_MOUSE
NC score	0.096082 (rank : 417)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	326	Target Neighborhood Hits	528	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

LRC45_HUMAN
NC score	0.096036 (rank : 418)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	326	Target Neighborhood Hits	933	Shared Neighborhood Hits	120
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

OFD1_HUMAN
NC score	0.095837 (rank : 419)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	326	Target Neighborhood Hits	753	Shared Neighborhood Hits	108
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

CCD62_HUMAN
NC score	0.095739 (rank : 420)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	326	Target Neighborhood Hits	631	Shared Neighborhood Hits	99
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

TEX14_MOUSE
NC score	0.095680 (rank : 421)	θ value	θ > 10 (rank : 1142)
Query Neighborhood Hits	326	Target Neighborhood Hits	1333	Shared Neighborhood Hits	146
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

HOOK3_HUMAN
NC score	0.095662 (rank : 422)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	326	Target Neighborhood Hits	1070	Shared Neighborhood Hits	125
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

STK10_HUMAN
NC score	0.095357 (rank : 423)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	326	Target Neighborhood Hits	1921	Shared Neighborhood Hits	194
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MYH6_MOUSE
NC score	0.095324 (rank : 424)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	326	Target Neighborhood Hits	1501	Shared Neighborhood Hits	146
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

AN30A_HUMAN
NC score	0.095260 (rank : 425)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	326	Target Neighborhood Hits	1119	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

C8AP2_HUMAN
NC score	0.095211 (rank : 426)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	326	Target Neighborhood Hits	548	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

HIRP3_HUMAN
NC score	0.095063 (rank : 427)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	326	Target Neighborhood Hits	323	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

TOP1_MOUSE
NC score	0.095041 (rank : 428)	θ value	1.06291 (rank : 174)
Query Neighborhood Hits	326	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

PLEC1_HUMAN
NC score	0.095041 (rank : 429)	θ value	0.0252991 (rank : 58)
Query Neighborhood Hits	326	Target Neighborhood Hits	1326	Shared Neighborhood Hits	123
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

GRAP1_HUMAN
NC score	0.095008 (rank : 430)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	326	Target Neighborhood Hits	944	Shared Neighborhood Hits	116
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

LIPA2_HUMAN
NC score	0.094939 (rank : 431)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	326	Target Neighborhood Hits	1044	Shared Neighborhood Hits	132
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

TACC2_MOUSE
NC score	0.094929 (rank : 432)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	326	Target Neighborhood Hits	774	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

CCD13_HUMAN
NC score	0.094773 (rank : 433)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	326	Target Neighborhood Hits	721	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

MYH7_HUMAN
NC score	0.094719 (rank : 434)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	326	Target Neighborhood Hits	1559	Shared Neighborhood Hits	158
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PPIG_HUMAN
NC score	0.094708 (rank : 435)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	326	Target Neighborhood Hits	670	Shared Neighborhood Hits	125
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

GCC1_HUMAN
NC score	0.094465 (rank : 436)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	326	Target Neighborhood Hits	887	Shared Neighborhood Hits	106
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

MYH1_MOUSE
NC score	0.094260 (rank : 437)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	326	Target Neighborhood Hits	1461	Shared Neighborhood Hits	144
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

GLE1_HUMAN
NC score	0.094217 (rank : 438)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	326	Target Neighborhood Hits	445	Shared Neighborhood Hits	92
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

ZN318_MOUSE
NC score	0.094154 (rank : 439)	θ value	θ > 10 (rank : 1228)
Query Neighborhood Hits	326	Target Neighborhood Hits	642	Shared Neighborhood Hits	108
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

YTDC1_HUMAN
NC score	0.094114 (rank : 440)	θ value	θ > 10 (rank : 1225)
Query Neighborhood Hits	326	Target Neighborhood Hits	458	Shared Neighborhood Hits	76
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

LRRF2_MOUSE
NC score	0.094104 (rank : 441)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	326	Target Neighborhood Hits	556	Shared Neighborhood Hits	92
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

RPGR1_MOUSE
NC score	0.094038 (rank : 442)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	326	Target Neighborhood Hits	713	Shared Neighborhood Hits	91
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

DYNA_HUMAN
NC score	0.094007 (rank : 443)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	326	Target Neighborhood Hits	1194	Shared Neighborhood Hits	133
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

MYO5C_HUMAN
NC score	0.094007 (rank : 444)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	326	Target Neighborhood Hits	1206	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYH2_HUMAN
NC score	0.093971 (rank : 445)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	326	Target Neighborhood Hits	1491	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

KINH_MOUSE
NC score	0.093727 (rank : 446)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	326	Target Neighborhood Hits	1082	Shared Neighborhood Hits	153
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

RBCC1_HUMAN
NC score	0.093626 (rank : 447)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	326	Target Neighborhood Hits	1023	Shared Neighborhood Hits	123
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CA065_HUMAN
NC score	0.093584 (rank : 448)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	326	Target Neighborhood Hits	469	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

C102B_HUMAN
NC score	0.093476 (rank : 449)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	326	Target Neighborhood Hits	542	Shared Neighborhood Hits	88
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

ADIP_HUMAN
NC score	0.092972 (rank : 450)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	326	Target Neighborhood Hits	470	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

HOOK3_MOUSE
NC score	0.092737 (rank : 451)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	326	Target Neighborhood Hits	1007	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

MYH1_HUMAN
NC score	0.092638 (rank : 452)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	326	Target Neighborhood Hits	1478	Shared Neighborhood Hits	150
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

RABE2_MOUSE
NC score	0.092581 (rank : 453)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	326	Target Neighborhood Hits	598	Shared Neighborhood Hits	98
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

PLCB1_HUMAN
NC score	0.092543 (rank : 454)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	326	Target Neighborhood Hits	614	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

ZRF1_HUMAN
NC score	0.092435 (rank : 455)	θ value	0.62314 (rank : 150)
Query Neighborhood Hits	326	Target Neighborhood Hits	457	Shared Neighborhood Hits	63
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

TARA_HUMAN
NC score	0.092422 (rank : 456)	θ value	1.81305 (rank : 208)
Query Neighborhood Hits	326	Target Neighborhood Hits	1626	Shared Neighborhood Hits	142
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GLE1_MOUSE
NC score	0.092323 (rank : 457)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	326	Target Neighborhood Hits	504	Shared Neighborhood Hits	103
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

SMC4_HUMAN
NC score	0.092235 (rank : 458)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	326	Target Neighborhood Hits	937	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

KTN1_HUMAN
NC score	0.092108 (rank : 459)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	326	Target Neighborhood Hits	1197	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

DYNA_MOUSE
NC score	0.092015 (rank : 460)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	326	Target Neighborhood Hits	1084	Shared Neighborhood Hits	124
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

MYO5A_HUMAN
NC score	0.092012 (rank : 461)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	326	Target Neighborhood Hits	1092	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

FYCO1_MOUSE
NC score	0.091971 (rank : 462)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	326	Target Neighborhood Hits	1059	Shared Neighborhood Hits	107
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

MINT_HUMAN
NC score	0.091960 (rank : 463)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	326	Target Neighborhood Hits	1291	Shared Neighborhood Hits	130
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYO5A_MOUSE
NC score	0.091730 (rank : 464)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	326	Target Neighborhood Hits	1117	Shared Neighborhood Hits	151
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

NEMO_MOUSE
NC score	0.091588 (rank : 465)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	326	Target Neighborhood Hits	658	Shared Neighborhood Hits	95
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

MYH4_MOUSE
NC score	0.091570 (rank : 466)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	326	Target Neighborhood Hits	1476	Shared Neighborhood Hits	143
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

TEX9_MOUSE
NC score	0.091396 (rank : 467)	θ value	θ > 10 (rank : 1144)
Query Neighborhood Hits	326	Target Neighborhood Hits	581	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

RFIP4_HUMAN
NC score	0.091189 (rank : 468)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	326	Target Neighborhood Hits	785	Shared Neighborhood Hits	113
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RABE2_HUMAN
NC score	0.091175 (rank : 469)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	326	Target Neighborhood Hits	545	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

CJ118_HUMAN
NC score	0.091064 (rank : 470)	θ value	8.99809 (rank : 311)
Query Neighborhood Hits	326	Target Neighborhood Hits	937	Shared Neighborhood Hits	99
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CEP55_HUMAN
NC score	0.090842 (rank : 471)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	326	Target Neighborhood Hits	504	Shared Neighborhood Hits	87
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

SOCS1_MOUSE
NC score	0.090704 (rank : 472)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	326	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	O35716, O35960, Q3U3L0	Gene names	Socs1, Cish1, Ssi1
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1).

CTGE5_MOUSE
NC score	0.090617 (rank : 473)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	326	Target Neighborhood Hits	928	Shared Neighborhood Hits	126
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

RAI14_MOUSE
NC score	0.090534 (rank : 474)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	326	Target Neighborhood Hits	1505	Shared Neighborhood Hits	157
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

NUF2_HUMAN
NC score	0.090525 (rank : 475)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	326	Target Neighborhood Hits	661	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

FYCO1_HUMAN
NC score	0.090445 (rank : 476)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	326	Target Neighborhood Hits	1149	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

TUFT1_HUMAN
NC score	0.090309 (rank : 477)	θ value	θ > 10 (rank : 1182)
Query Neighborhood Hits	326	Target Neighborhood Hits	686	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TEX14_HUMAN
NC score	0.090132 (rank : 478)	θ value	θ > 10 (rank : 1141)
Query Neighborhood Hits	326	Target Neighborhood Hits	1103	Shared Neighborhood Hits	111
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

LCP2_HUMAN
NC score	0.090116 (rank : 479)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	326	Target Neighborhood Hits	531	Shared Neighborhood Hits	67
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

STMN4_HUMAN
NC score	0.090025 (rank : 480)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	101
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
NC score	0.090004 (rank : 481)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	101
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

TPM4_MOUSE
NC score	0.089965 (rank : 482)	θ value	θ > 10 (rank : 1169)
Query Neighborhood Hits	326	Target Neighborhood Hits	703	Shared Neighborhood Hits	106
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TACC1_MOUSE
NC score	0.089941 (rank : 483)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	326	Target Neighborhood Hits	667	Shared Neighborhood Hits	106
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

STIM1_MOUSE
NC score	0.089791 (rank : 484)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	326	Target Neighborhood Hits	660	Shared Neighborhood Hits	125
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TACC3_MOUSE
NC score	0.089776 (rank : 485)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	326	Target Neighborhood Hits	607	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

PLCB3_HUMAN
NC score	0.089691 (rank : 486)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	326	Target Neighborhood Hits	445	Shared Neighborhood Hits	112
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

NOP14_MOUSE
NC score	0.089584 (rank : 487)	θ value	1.81305 (rank : 202)
Query Neighborhood Hits	326	Target Neighborhood Hits	324	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

TRAIP_MOUSE
NC score	0.089536 (rank : 488)	θ value	θ > 10 (rank : 1174)
Query Neighborhood Hits	326	Target Neighborhood Hits	745	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

CAR11_HUMAN
NC score	0.089507 (rank : 489)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	326	Target Neighborhood Hits	690	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

DMD_MOUSE
NC score	0.089430 (rank : 490)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	326	Target Neighborhood Hits	1111	Shared Neighborhood Hits	139
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

ANR12_HUMAN
NC score	0.089393 (rank : 491)	θ value	1.81305 (rank : 192)
Query Neighborhood Hits	326	Target Neighborhood Hits	1081	Shared Neighborhood Hits	150
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

SOCS1_HUMAN
NC score	0.089337 (rank : 492)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	326	Target Neighborhood Hits	79	Shared Neighborhood Hits	43
SwissProt Accessions	O15524, O15097, Q9NSA7	Gene names	SOCS1, SSI1, TIP3
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3).

BPAEA_HUMAN
NC score	0.089144 (rank : 493)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	326	Target Neighborhood Hits	1369	Shared Neighborhood Hits	135
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

KI21A_HUMAN
NC score	0.089114 (rank : 494)	θ value	4.03905 (rank : 248)
Query Neighborhood Hits	326	Target Neighborhood Hits	1543	Shared Neighborhood Hits	163
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

TRAIP_HUMAN
NC score	0.088710 (rank : 495)	θ value	θ > 10 (rank : 1173)
Query Neighborhood Hits	326	Target Neighborhood Hits	780	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

U2AFM_HUMAN
NC score	0.088639 (rank : 496)	θ value	θ > 10 (rank : 1199)
Query Neighborhood Hits	326	Target Neighborhood Hits	577	Shared Neighborhood Hits	87
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

NPHP1_HUMAN
NC score	0.088505 (rank : 497)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	326	Target Neighborhood Hits	288	Shared Neighborhood Hits	65
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

CTRO_MOUSE
NC score	0.088495 (rank : 498)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	326	Target Neighborhood Hits	2344	Shared Neighborhood Hits	206
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SAS6_HUMAN
NC score	0.088442 (rank : 499)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	326	Target Neighborhood Hits	791	Shared Neighborhood Hits	103
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

TNIP3_HUMAN
NC score	0.088389 (rank : 500)	θ value	θ > 10 (rank : 1153)
Query Neighborhood Hits	326	Target Neighborhood Hits	511	Shared Neighborhood Hits	88
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

CCD42_HUMAN
NC score	0.088377 (rank : 501)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	326	Target Neighborhood Hits	406	Shared Neighborhood Hits	82
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

SPTA2_HUMAN
NC score	0.088377 (rank : 502)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	326	Target Neighborhood Hits	888	Shared Neighborhood Hits	130
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

KNTC2_MOUSE
NC score	0.088128 (rank : 503)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	326	Target Neighborhood Hits	692	Shared Neighborhood Hits	90
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

TAOK1_HUMAN
NC score	0.088048 (rank : 504)	θ value	5.27518 (rank : 281)
Query Neighborhood Hits	326	Target Neighborhood Hits	1734	Shared Neighborhood Hits	188
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

U2AFL_MOUSE
NC score	0.087897 (rank : 505)	θ value	0.62314 (rank : 147)
Query Neighborhood Hits	326	Target Neighborhood Hits	389	Shared Neighborhood Hits	63
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

RSF1_HUMAN
NC score	0.087865 (rank : 506)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	326	Target Neighborhood Hits	539	Shared Neighborhood Hits	83
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

MYH4_HUMAN
NC score	0.087823 (rank : 507)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	326	Target Neighborhood Hits	1377	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

LRC27_HUMAN
NC score	0.087822 (rank : 508)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	326	Target Neighborhood Hits	710	Shared Neighborhood Hits	111
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

CR034_MOUSE
NC score	0.087634 (rank : 509)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	326	Target Neighborhood Hits	643	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

TACC3_HUMAN
NC score	0.087603 (rank : 510)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	326	Target Neighborhood Hits	779	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

GOG8A_HUMAN
NC score	0.087507 (rank : 511)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	326	Target Neighborhood Hits	635	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

TACC1_HUMAN
NC score	0.087391 (rank : 512)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	326	Target Neighborhood Hits	597	Shared Neighborhood Hits	104
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

IWS1_MOUSE
NC score	0.087315 (rank : 513)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	326	Target Neighborhood Hits	1258	Shared Neighborhood Hits	110
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BAZ1B_HUMAN
NC score	0.087252 (rank : 514)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	326	Target Neighborhood Hits	701	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

RUFY3_HUMAN
NC score	0.087230 (rank : 515)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	326	Target Neighborhood Hits	594	Shared Neighborhood Hits	110
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

KIF5C_MOUSE
NC score	0.087033 (rank : 516)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	326	Target Neighborhood Hits	1040	Shared Neighborhood Hits	139
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

U2AFM_MOUSE
NC score	0.086999 (rank : 517)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	326	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

CTGE5_HUMAN
NC score	0.086987 (rank : 518)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	326	Target Neighborhood Hits	800	Shared Neighborhood Hits	119
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

DMN_HUMAN
NC score	0.086905 (rank : 519)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	326	Target Neighborhood Hits	690	Shared Neighborhood Hits	143
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

RADI_HUMAN
NC score	0.086644 (rank : 520)	θ value	0.365318 (rank : 122)
Query Neighborhood Hits	326	Target Neighborhood Hits	741	Shared Neighborhood Hits	100
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

TARA_MOUSE
NC score	0.086631 (rank : 521)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	326	Target Neighborhood Hits	1133	Shared Neighborhood Hits	116
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RBBP8_HUMAN
NC score	0.086521 (rank : 522)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	326	Target Neighborhood Hits	476	Shared Neighborhood Hits	95
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

STIM1_HUMAN
NC score	0.086378 (rank : 523)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	326	Target Neighborhood Hits	665	Shared Neighborhood Hits	120
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

GP73_MOUSE
NC score	0.086355 (rank : 524)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	326	Target Neighborhood Hits	506	Shared Neighborhood Hits	93
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

CDR2_MOUSE
NC score	0.086311 (rank : 525)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	326	Target Neighborhood Hits	482	Shared Neighborhood Hits	82
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

MRCKB_HUMAN
NC score	0.086274 (rank : 526)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	326	Target Neighborhood Hits	2239	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

LRRF1_HUMAN
NC score	0.086262 (rank : 527)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	326	Target Neighborhood Hits	625	Shared Neighborhood Hits	104
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

GOGA2_HUMAN
NC score	0.086232 (rank : 528)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	326	Target Neighborhood Hits	856	Shared Neighborhood Hits	94
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

MRCKB_MOUSE
NC score	0.086226 (rank : 529)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	326	Target Neighborhood Hits	2180	Shared Neighborhood Hits	201
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CEP70_HUMAN
NC score	0.086117 (rank : 530)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	326	Target Neighborhood Hits	432	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

PLCB1_MOUSE
NC score	0.086109 (rank : 531)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	326	Target Neighborhood Hits	531	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

HIP1R_HUMAN
NC score	0.086103 (rank : 532)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	326	Target Neighborhood Hits	809	Shared Neighborhood Hits	109
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

IMMT_HUMAN
NC score	0.086059 (rank : 533)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	326	Target Neighborhood Hits	494	Shared Neighborhood Hits	97
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

ROCK1_MOUSE
NC score	0.085740 (rank : 534)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	326	Target Neighborhood Hits	2126	Shared Neighborhood Hits	191
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

TOP1_HUMAN
NC score	0.085576 (rank : 535)	θ value	0.21417 (rank : 111)
Query Neighborhood Hits	326	Target Neighborhood Hits	207	Shared Neighborhood Hits	49
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

TAOK1_MOUSE
NC score	0.085463 (rank : 536)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	326	Target Neighborhood Hits	1720	Shared Neighborhood Hits	185
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

RUFY3_MOUSE
NC score	0.085399 (rank : 537)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	326	Target Neighborhood Hits	579	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

PHF20_HUMAN
NC score	0.085358 (rank : 538)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	326	Target Neighborhood Hits	394	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

CF182_MOUSE
NC score	0.085262 (rank : 539)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	326	Target Neighborhood Hits	551	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

SFRS4_MOUSE
NC score	0.084898 (rank : 540)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	326	Target Neighborhood Hits	406	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SMC4_MOUSE
NC score	0.084658 (rank : 541)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	326	Target Neighborhood Hits	830	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

CT116_MOUSE
NC score	0.084417 (rank : 542)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	326	Target Neighborhood Hits	268	Shared Neighborhood Hits	52
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

CS029_HUMAN
NC score	0.084264 (rank : 543)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	326	Target Neighborhood Hits	329	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

HOOK1_HUMAN
NC score	0.083910 (rank : 544)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	326	Target Neighborhood Hits	942	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

T3JAM_HUMAN
NC score	0.083852 (rank : 545)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	326	Target Neighborhood Hits	533	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

MOES_MOUSE
NC score	0.083809 (rank : 546)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	326	Target Neighborhood Hits	923	Shared Neighborhood Hits	112
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NPHP1_MOUSE
NC score	0.083546 (rank : 547)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	326	Target Neighborhood Hits	267	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

SYNE1_HUMAN
NC score	0.083489 (rank : 548)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	326	Target Neighborhood Hits	1484	Shared Neighborhood Hits	122
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYNE2_HUMAN
NC score	0.083406 (rank : 549)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	326	Target Neighborhood Hits	1323	Shared Neighborhood Hits	131
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

DYXC1_HUMAN
NC score	0.083392 (rank : 550)	θ value	1.81305 (rank : 197)
Query Neighborhood Hits	326	Target Neighborhood Hits	261	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

CDC37_MOUSE
NC score	0.083150 (rank : 551)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	326	Target Neighborhood Hits	359	Shared Neighborhood Hits	83
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CCHCR_HUMAN
NC score	0.083116 (rank : 552)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	326	Target Neighborhood Hits	717	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

TRAK1_HUMAN
NC score	0.082993 (rank : 553)	θ value	θ > 10 (rank : 1175)
Query Neighborhood Hits	326	Target Neighborhood Hits	660	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

ADIP_MOUSE
NC score	0.082923 (rank : 554)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	326	Target Neighborhood Hits	415	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

PHLB1_HUMAN
NC score	0.082909 (rank : 555)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	326	Target Neighborhood Hits	1038	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

INVO_HUMAN
NC score	0.082815 (rank : 556)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	326	Target Neighborhood Hits	636	Shared Neighborhood Hits	69
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

HOOK1_MOUSE
NC score	0.082800 (rank : 557)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	326	Target Neighborhood Hits	910	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

DMD_HUMAN
NC score	0.082796 (rank : 558)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	326	Target Neighborhood Hits	1135	Shared Neighborhood Hits	136
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

MOES_HUMAN
NC score	0.082490 (rank : 559)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	326	Target Neighborhood Hits	892	Shared Neighborhood Hits	110
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

HAP1_HUMAN
NC score	0.082409 (rank : 560)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	326	Target Neighborhood Hits	606	Shared Neighborhood Hits	90
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

TNNT3_MOUSE
NC score	0.082373 (rank : 561)	θ value	θ > 10 (rank : 1159)
Query Neighborhood Hits	326	Target Neighborhood Hits	317	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

NUF2_MOUSE
NC score	0.082372 (rank : 562)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	326	Target Neighborhood Hits	585	Shared Neighborhood Hits	92
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

CLCB_MOUSE
NC score	0.082182 (rank : 563)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	326	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q6IRU5, Q8BR04, Q8CDX9, Q9CV35	Gene names	Cltb
Domain Architecture	No domain graphic available
Description	Clathrin light chain B (Lcb).

CCD11_MOUSE
NC score	0.082068 (rank : 564)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	326	Target Neighborhood Hits	498	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CKAP4_HUMAN
NC score	0.081945 (rank : 565)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	326	Target Neighborhood Hits	592	Shared Neighborhood Hits	86
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MYH14_HUMAN
NC score	0.081944 (rank : 566)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	326	Target Neighborhood Hits	995	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

BLNK_HUMAN
NC score	0.081907 (rank : 567)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	326	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

TCAL5_HUMAN
NC score	0.081798 (rank : 568)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	326	Target Neighborhood Hits	806	Shared Neighborhood Hits	101
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

INVO_MOUSE
NC score	0.081746 (rank : 569)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	326	Target Neighborhood Hits	474	Shared Neighborhood Hits	72
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

PPIP1_HUMAN
NC score	0.081651 (rank : 570)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	326	Target Neighborhood Hits	389	Shared Neighborhood Hits	84
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

BPA1_MOUSE
NC score	0.081427 (rank : 571)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	326	Target Neighborhood Hits	1477	Shared Neighborhood Hits	133
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD50_HUMAN
NC score	0.081289 (rank : 572)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	326	Target Neighborhood Hits	237	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

ROCK2_MOUSE
NC score	0.081259 (rank : 573)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	326	Target Neighborhood Hits	2072	Shared Neighborhood Hits	192
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RADI_MOUSE
NC score	0.081248 (rank : 574)	θ value	0.813845 (rank : 158)
Query Neighborhood Hits	326	Target Neighborhood Hits	773	Shared Neighborhood Hits	97
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

PPIP1_MOUSE
NC score	0.081144 (rank : 575)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	326	Target Neighborhood Hits	377	Shared Neighborhood Hits	85
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

ROCK2_HUMAN
NC score	0.080926 (rank : 576)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	326	Target Neighborhood Hits	2073	Shared Neighborhood Hits	195
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

STMN2_HUMAN
NC score	0.080746 (rank : 577)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	326	Target Neighborhood Hits	458	Shared Neighborhood Hits	94
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
NC score	0.080746 (rank : 578)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	326	Target Neighborhood Hits	458	Shared Neighborhood Hits	94
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

RPGR1_HUMAN
NC score	0.080730 (rank : 579)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	326	Target Neighborhood Hits	578	Shared Neighborhood Hits	85
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

KI67_HUMAN
NC score	0.080413 (rank : 580)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	326	Target Neighborhood Hits	581	Shared Neighborhood Hits	77
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

TEX9_HUMAN
NC score	0.080139 (rank : 581)	θ value	θ > 10 (rank : 1143)
Query Neighborhood Hits	326	Target Neighborhood Hits	541	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

SKIL_MOUSE
NC score	0.079666 (rank : 582)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	326	Target Neighborhood Hits	719	Shared Neighborhood Hits	110
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

RUFY1_HUMAN
NC score	0.079598 (rank : 583)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	326	Target Neighborhood Hits	848	Shared Neighborhood Hits	103
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

NEB2_MOUSE
NC score	0.079494 (rank : 584)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	326	Target Neighborhood Hits	889	Shared Neighborhood Hits	115
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

RFIP4_MOUSE
NC score	0.079464 (rank : 585)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	326	Target Neighborhood Hits	708	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

KNTC2_HUMAN
NC score	0.079398 (rank : 586)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	326	Target Neighborhood Hits	673	Shared Neighborhood Hits	85
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KIF23_HUMAN
NC score	0.079321 (rank : 587)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	326	Target Neighborhood Hits	618	Shared Neighborhood Hits	116
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

STYK1_MOUSE
NC score	0.079302 (rank : 588)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	326	Target Neighborhood Hits	779	Shared Neighborhood Hits	41
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

CEP57_MOUSE
NC score	0.079300 (rank : 589)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	326	Target Neighborhood Hits	580	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

LUZP1_HUMAN
NC score	0.079288 (rank : 590)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	326	Target Neighborhood Hits	739	Shared Neighborhood Hits	95
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MIPO1_HUMAN
NC score	0.079245 (rank : 591)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	326	Target Neighborhood Hits	486	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

BAP29_HUMAN
NC score	0.079226 (rank : 592)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	326	Target Neighborhood Hits	362	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

CKAP4_MOUSE
NC score	0.079222 (rank : 593)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	326	Target Neighborhood Hits	596	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

STYK1_HUMAN
NC score	0.079182 (rank : 594)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	326	Target Neighborhood Hits	786	Shared Neighborhood Hits	41
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

RYK_HUMAN
NC score	0.079110 (rank : 595)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	326	Target Neighborhood Hits	701	Shared Neighborhood Hits	41
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

NFH_HUMAN
NC score	0.079090 (rank : 596)	θ value	0.62314 (rank : 141)
Query Neighborhood Hits	326	Target Neighborhood Hits	1242	Shared Neighborhood Hits	134
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CIR_HUMAN
NC score	0.079079 (rank : 597)	θ value	0.279714 (rank : 114)
Query Neighborhood Hits	326	Target Neighborhood Hits	249	Shared Neighborhood Hits	39
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

ZWINT_HUMAN
NC score	0.079051 (rank : 598)	θ value	θ > 10 (rank : 1229)
Query Neighborhood Hits	326	Target Neighborhood Hits	333	Shared Neighborhood Hits	68
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

SPC24_HUMAN
NC score	0.078983 (rank : 599)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	326	Target Neighborhood Hits	324	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

VDP_HUMAN
NC score	0.078934 (rank : 600)	θ value	θ > 10 (rank : 1207)
Query Neighborhood Hits	326	Target Neighborhood Hits	645	Shared Neighborhood Hits	87
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

ACK1_MOUSE
NC score	0.078865 (rank : 601)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	326	Target Neighborhood Hits	1080	Shared Neighborhood Hits	55
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

PACN3_HUMAN
NC score	0.078673 (rank : 602)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	326	Target Neighborhood Hits	385	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

TPM1_MOUSE
NC score	0.078667 (rank : 603)	θ value	θ > 10 (rank : 1163)
Query Neighborhood Hits	326	Target Neighborhood Hits	729	Shared Neighborhood Hits	98
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

RYK_MOUSE
NC score	0.078603 (rank : 604)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	326	Target Neighborhood Hits	715	Shared Neighborhood Hits	41
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

DLG5_HUMAN
NC score	0.078522 (rank : 605)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	326	Target Neighborhood Hits	1088	Shared Neighborhood Hits	116
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

STMN3_HUMAN
NC score	0.078497 (rank : 606)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	326	Target Neighborhood Hits	348	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NZ72, O75527, Q969Y4	Gene names	STMN3, SCLIP
Domain Architecture
Description	Stathmin-3 (SCG10-like protein).

BAZ1A_HUMAN
NC score	0.078383 (rank : 607)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	326	Target Neighborhood Hits	693	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

ACK1_HUMAN
NC score	0.078117 (rank : 608)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	326	Target Neighborhood Hits	1140	Shared Neighborhood Hits	59
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CCD27_HUMAN
NC score	0.077910 (rank : 609)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	326	Target Neighborhood Hits	594	Shared Neighborhood Hits	82
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

MYO5B_HUMAN
NC score	0.077907 (rank : 610)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	326	Target Neighborhood Hits	911	Shared Neighborhood Hits	131
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

EZRI_MOUSE
NC score	0.077889 (rank : 611)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	326	Target Neighborhood Hits	693	Shared Neighborhood Hits	110
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

TPM1_HUMAN
NC score	0.077884 (rank : 612)	θ value	θ > 10 (rank : 1162)
Query Neighborhood Hits	326	Target Neighborhood Hits	716	Shared Neighborhood Hits	96
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

ELOA1_HUMAN
NC score	0.077798 (rank : 613)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	326	Target Neighborhood Hits	388	Shared Neighborhood Hits	77
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MPP9_HUMAN
NC score	0.077748 (rank : 614)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	326	Target Neighborhood Hits	529	Shared Neighborhood Hits	76
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

3BP5_MOUSE
NC score	0.077729 (rank : 615)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	326	Target Neighborhood Hits	346	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

3BP5_HUMAN
NC score	0.077630 (rank : 616)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	326	Target Neighborhood Hits	375	Shared Neighborhood Hits	71
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

LTK_HUMAN
NC score	0.077625 (rank : 617)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	326	Target Neighborhood Hits	774	Shared Neighborhood Hits	41
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

MACF4_HUMAN
NC score	0.077586 (rank : 618)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	326	Target Neighborhood Hits	1321	Shared Neighborhood Hits	121
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SPAG5_HUMAN
NC score	0.077566 (rank : 619)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	326	Target Neighborhood Hits	625	Shared Neighborhood Hits	91
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

TXLNA_HUMAN
NC score	0.077515 (rank : 620)	θ value	θ > 10 (rank : 1186)
Query Neighborhood Hits	326	Target Neighborhood Hits	982	Shared Neighborhood Hits	112
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

EZRI_HUMAN
NC score	0.077488 (rank : 621)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	326	Target Neighborhood Hits	663	Shared Neighborhood Hits	104
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

NEB2_HUMAN
NC score	0.077483 (rank : 622)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	326	Target Neighborhood Hits	883	Shared Neighborhood Hits	114
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

WDR60_MOUSE
NC score	0.077417 (rank : 623)	θ value	θ > 10 (rank : 1219)
Query Neighborhood Hits	326	Target Neighborhood Hits	344	Shared Neighborhood Hits	75
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

SDPR_HUMAN
NC score	0.077139 (rank : 624)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	326	Target Neighborhood Hits	337	Shared Neighborhood Hits	78
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

CEP70_MOUSE
NC score	0.077042 (rank : 625)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	326	Target Neighborhood Hits	532	Shared Neighborhood Hits	87
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

HOOK2_HUMAN
NC score	0.077017 (rank : 626)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	326	Target Neighborhood Hits	714	Shared Neighborhood Hits	98
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

TXLNA_MOUSE
NC score	0.076931 (rank : 627)	θ value	θ > 10 (rank : 1187)
Query Neighborhood Hits	326	Target Neighborhood Hits	846	Shared Neighborhood Hits	107
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

SRBS1_HUMAN
NC score	0.076911 (rank : 628)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	326	Target Neighborhood Hits	396	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

NFM_MOUSE
NC score	0.076897 (rank : 629)	θ value	4.03905 (rank : 256)
Query Neighborhood Hits	326	Target Neighborhood Hits	1159	Shared Neighborhood Hits	135
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

MINT_MOUSE
NC score	0.076803 (rank : 630)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	326	Target Neighborhood Hits	1514	Shared Neighborhood Hits	114
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CT116_HUMAN
NC score	0.076685 (rank : 631)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	326	Target Neighborhood Hits	294	Shared Neighborhood Hits	55
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

PRC1_MOUSE
NC score	0.076573 (rank : 632)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	326	Target Neighborhood Hits	382	Shared Neighborhood Hits	83
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

ALK_MOUSE
NC score	0.076538 (rank : 633)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	326	Target Neighborhood Hits	811	Shared Neighborhood Hits	42
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

CTGE6_HUMAN
NC score	0.076401 (rank : 634)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	326	Target Neighborhood Hits	650	Shared Neighborhood Hits	101
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

LTK_MOUSE
NC score	0.076397 (rank : 635)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	326	Target Neighborhood Hits	770	Shared Neighborhood Hits	41
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

HOOK2_MOUSE
NC score	0.076366 (rank : 636)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	326	Target Neighborhood Hits	736	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

ROCK1_HUMAN
NC score	0.076200 (rank : 637)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	326	Target Neighborhood Hits	2000	Shared Neighborhood Hits	177
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

MYO6_HUMAN
NC score	0.076128 (rank : 638)	θ value	4.03905 (rank : 254)
Query Neighborhood Hits	326	Target Neighborhood Hits	727	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

ALK_HUMAN
NC score	0.076121 (rank : 639)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	326	Target Neighborhood Hits	795	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

SFRIP_HUMAN
NC score	0.076114 (rank : 640)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	326	Target Neighborhood Hits	530	Shared Neighborhood Hits	72
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CTRO_HUMAN
NC score	0.075940 (rank : 641)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	326	Target Neighborhood Hits	2092	Shared Neighborhood Hits	179
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

LIPB1_MOUSE
NC score	0.075938 (rank : 642)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	326	Target Neighborhood Hits	727	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

NFM_HUMAN
NC score	0.075837 (rank : 643)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	326	Target Neighborhood Hits	1328	Shared Neighborhood Hits	143
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PLVAP_HUMAN
NC score	0.075535 (rank : 644)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	326	Target Neighborhood Hits	397	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

KI21A_MOUSE
NC score	0.075428 (rank : 645)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	326	Target Neighborhood Hits	1317	Shared Neighborhood Hits	148
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

NDEL1_HUMAN
NC score	0.075316 (rank : 646)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	326	Target Neighborhood Hits	415	Shared Neighborhood Hits	65
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

SPTA1_HUMAN
NC score	0.075235 (rank : 647)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	326	Target Neighborhood Hits	748	Shared Neighborhood Hits	120
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

NDEL1_MOUSE
NC score	0.075032 (rank : 648)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	326	Target Neighborhood Hits	420	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

BLNK_MOUSE
NC score	0.074924 (rank : 649)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	326	Target Neighborhood Hits	296	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

EP15_MOUSE
NC score	0.074877 (rank : 650)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	326	Target Neighborhood Hits	820	Shared Neighborhood Hits	81
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MACF1_MOUSE
NC score	0.074803 (rank : 651)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	326	Target Neighborhood Hits	1313	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

RUFY2_MOUSE
NC score	0.074700 (rank : 652)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	326	Target Neighborhood Hits	820	Shared Neighborhood Hits	102
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

IDLC_MOUSE
NC score	0.074665 (rank : 653)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	326	Target Neighborhood Hits	321	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

MACF1_HUMAN
NC score	0.074652 (rank : 654)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	326	Target Neighborhood Hits	1341	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

FAK2_HUMAN
NC score	0.074453 (rank : 655)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	326	Target Neighborhood Hits	847	Shared Neighborhood Hits	46
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

ROS_HUMAN
NC score	0.074435 (rank : 656)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	326	Target Neighborhood Hits	907	Shared Neighborhood Hits	41
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SLK_MOUSE
NC score	0.074290 (rank : 657)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	326	Target Neighborhood Hits	1798	Shared Neighborhood Hits	182
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TNK1_HUMAN
NC score	0.074162 (rank : 658)	θ value	θ > 10 (rank : 1154)
Query Neighborhood Hits	326	Target Neighborhood Hits	815	Shared Neighborhood Hits	47
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

FAK2_MOUSE
NC score	0.074123 (rank : 659)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	326	Target Neighborhood Hits	851	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

PACN3_MOUSE
NC score	0.074026 (rank : 660)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	326	Target Neighborhood Hits	380	Shared Neighborhood Hits	84
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

WDR60_HUMAN
NC score	0.074006 (rank : 661)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	326	Target Neighborhood Hits	286	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

CAR10_HUMAN
NC score	0.073903 (rank : 662)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	326	Target Neighborhood Hits	569	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CEP57_HUMAN
NC score	0.073886 (rank : 663)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	326	Target Neighborhood Hits	576	Shared Neighborhood Hits	94
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

AATK_MOUSE
NC score	0.073762 (rank : 664)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	326	Target Neighborhood Hits	942	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

IDLC_HUMAN
NC score	0.073736 (rank : 665)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	326	Target Neighborhood Hits	348	Shared Neighborhood Hits	77
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

SLK_HUMAN
NC score	0.073711 (rank : 666)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	326	Target Neighborhood Hits	1775	Shared Neighborhood Hits	174
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TIM44_MOUSE
NC score	0.073615 (rank : 667)	θ value	θ > 10 (rank : 1150)
Query Neighborhood Hits	326	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

UBP8_HUMAN
NC score	0.073589 (rank : 668)	θ value	0.62314 (rank : 148)
Query Neighborhood Hits	326	Target Neighborhood Hits	751	Shared Neighborhood Hits	129
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

NEB1_HUMAN
NC score	0.073455 (rank : 669)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	326	Target Neighborhood Hits	829	Shared Neighborhood Hits	110
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

TAOK3_HUMAN
NC score	0.073429 (rank : 670)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	326	Target Neighborhood Hits	1494	Shared Neighborhood Hits	147
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

PRC1_HUMAN
NC score	0.073372 (rank : 671)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	326	Target Neighborhood Hits	328	Shared Neighborhood Hits	69
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

ANR11_HUMAN
NC score	0.073278 (rank : 672)	θ value	1.81305 (rank : 191)
Query Neighborhood Hits	326	Target Neighborhood Hits	1289	Shared Neighborhood Hits	129
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CRCM_HUMAN
NC score	0.073252 (rank : 673)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	326	Target Neighborhood Hits	520	Shared Neighborhood Hits	79
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

TNK1_MOUSE
NC score	0.073243 (rank : 674)	θ value	θ > 10 (rank : 1155)
Query Neighborhood Hits	326	Target Neighborhood Hits	806	Shared Neighborhood Hits	47
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

DDR1_MOUSE
NC score	0.073240 (rank : 675)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	326	Target Neighborhood Hits	818	Shared Neighborhood Hits	44
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

SNX23_HUMAN
NC score	0.073123 (rank : 676)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	326	Target Neighborhood Hits	944	Shared Neighborhood Hits	110
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

OXR1_MOUSE
NC score	0.073111 (rank : 677)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	326	Target Neighborhood Hits	516	Shared Neighborhood Hits	83
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

UTRO_HUMAN
NC score	0.073090 (rank : 678)	θ value	θ > 10 (rank : 1204)
Query Neighborhood Hits	326	Target Neighborhood Hits	960	Shared Neighborhood Hits	113
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

MERTK_HUMAN
NC score	0.072856 (rank : 679)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	326	Target Neighborhood Hits	988	Shared Neighborhood Hits	41
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

DDR1_HUMAN
NC score	0.072850 (rank : 680)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	326	Target Neighborhood Hits	819	Shared Neighborhood Hits	44
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

NSBP1_MOUSE
NC score	0.072839 (rank : 681)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	326	Target Neighborhood Hits	681	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

KIF5C_HUMAN
NC score	0.072833 (rank : 682)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	326	Target Neighborhood Hits	974	Shared Neighborhood Hits	115
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

SRBS1_MOUSE
NC score	0.072829 (rank : 683)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	326	Target Neighborhood Hits	409	Shared Neighborhood Hits	59
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

FLT3_HUMAN
NC score	0.072827 (rank : 684)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	326	Target Neighborhood Hits	843	Shared Neighborhood Hits	42
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

SPAG5_MOUSE
NC score	0.072646 (rank : 685)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	326	Target Neighborhood Hits	612	Shared Neighborhood Hits	79
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

FLT3_MOUSE
NC score	0.072643 (rank : 686)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	326	Target Neighborhood Hits	847	Shared Neighborhood Hits	41
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

U2AFL_HUMAN
NC score	0.072492 (rank : 687)	θ value	θ > 10 (rank : 1198)
Query Neighborhood Hits	326	Target Neighborhood Hits	503	Shared Neighborhood Hits	79
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

MYO10_HUMAN
NC score	0.072361 (rank : 688)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	326	Target Neighborhood Hits	920	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

TGON2_HUMAN
NC score	0.072337 (rank : 689)	θ value	θ > 10 (rank : 1145)
Query Neighborhood Hits	326	Target Neighborhood Hits	1037	Shared Neighborhood Hits	85
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

MRCKA_HUMAN
NC score	0.072321 (rank : 690)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	326	Target Neighborhood Hits	1999	Shared Neighborhood Hits	179
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MERTK_MOUSE
NC score	0.072244 (rank : 691)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	326	Target Neighborhood Hits	974	Shared Neighborhood Hits	43
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

ARHG7_MOUSE
NC score	0.072218 (rank : 692)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	326	Target Neighborhood Hits	396	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

CENPH_HUMAN
NC score	0.072177 (rank : 693)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	326	Target Neighborhood Hits	335	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

CCD38_HUMAN
NC score	0.072167 (rank : 694)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	326	Target Neighborhood Hits	287	Shared Neighborhood Hits	81
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

PACN2_MOUSE
NC score	0.072134 (rank : 695)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	326	Target Neighborhood Hits	382	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

FAK1_HUMAN
NC score	0.072087 (rank : 696)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	326	Target Neighborhood Hits	850	Shared Neighborhood Hits	42
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

CR034_HUMAN
NC score	0.072071 (rank : 697)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	326	Target Neighborhood Hits	538	Shared Neighborhood Hits	80
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

FAK1_MOUSE
NC score	0.072017 (rank : 698)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	326	Target Neighborhood Hits	850	Shared Neighborhood Hits	41
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

EP15_HUMAN
NC score	0.071979 (rank : 699)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	326	Target Neighborhood Hits	1021	Shared Neighborhood Hits	105
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ERBB3_MOUSE
NC score	0.071964 (rank : 700)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	326	Target Neighborhood Hits	898	Shared Neighborhood Hits	41
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB3_HUMAN
NC score	0.071919 (rank : 701)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	326	Target Neighborhood Hits	918	Shared Neighborhood Hits	41
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

IGF1R_HUMAN
NC score	0.071916 (rank : 702)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	326	Target Neighborhood Hits	977	Shared Neighborhood Hits	42
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

RUFY1_MOUSE
NC score	0.071876 (rank : 703)	θ value	6.88961 (rank : 301)
Query Neighborhood Hits	326	Target Neighborhood Hits	765	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

CSF1R_HUMAN
NC score	0.071857 (rank : 704)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	326	Target Neighborhood Hits	943	Shared Neighborhood Hits	42
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CF182_HUMAN
NC score	0.071813 (rank : 705)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	326	Target Neighborhood Hits	474	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

SPTA1_MOUSE
NC score	0.071772 (rank : 706)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	326	Target Neighborhood Hits	675	Shared Neighborhood Hits	109
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

IGF1R_MOUSE
NC score	0.071734 (rank : 707)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	326	Target Neighborhood Hits	973	Shared Neighborhood Hits	41
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

DDR2_HUMAN
NC score	0.071612 (rank : 708)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	326	Target Neighborhood Hits	818	Shared Neighborhood Hits	42
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

TEKT1_MOUSE
NC score	0.071603 (rank : 709)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	326	Target Neighborhood Hits	399	Shared Neighborhood Hits	71
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

M3KL4_HUMAN
NC score	0.071550 (rank : 710)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	326	Target Neighborhood Hits	1087	Shared Neighborhood Hits	80
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

INSRR_HUMAN
NC score	0.071498 (rank : 711)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	326	Target Neighborhood Hits	950	Shared Neighborhood Hits	41
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

ERBB2_HUMAN
NC score	0.071481 (rank : 712)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	326	Target Neighborhood Hits	1073	Shared Neighborhood Hits	44
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
NC score	0.071454 (rank : 713)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	326	Target Neighborhood Hits	918	Shared Neighborhood Hits	42
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

INSRR_MOUSE
NC score	0.071307 (rank : 714)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	326	Target Neighborhood Hits	961	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KIT_MOUSE
NC score	0.071280 (rank : 715)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	326	Target Neighborhood Hits	949	Shared Neighborhood Hits	41
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

DDR2_MOUSE
NC score	0.071261 (rank : 716)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	326	Target Neighborhood Hits	813	Shared Neighborhood Hits	42
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

KIT_HUMAN
NC score	0.071254 (rank : 717)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	326	Target Neighborhood Hits	953	Shared Neighborhood Hits	41
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

DZIP1_MOUSE
NC score	0.071246 (rank : 718)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	326	Target Neighborhood Hits	530	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

NTRK1_HUMAN
NC score	0.071169 (rank : 719)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	326	Target Neighborhood Hits	1023	Shared Neighborhood Hits	41
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

RON_MOUSE
NC score	0.071028 (rank : 720)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	326	Target Neighborhood Hits	836	Shared Neighborhood Hits	41
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ERBB4_HUMAN
NC score	0.071017 (rank : 721)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	326	Target Neighborhood Hits	910	Shared Neighborhood Hits	41
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

EPHAA_HUMAN
NC score	0.070944 (rank : 722)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	326	Target Neighborhood Hits	960	Shared Neighborhood Hits	40
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

SOCS5_HUMAN
NC score	0.070801 (rank : 723)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	326	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	O75159, Q8IYZ4	Gene names	SOCS5, CIS6, CISH5, CISH6, KIAA0671
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6).

AATK_HUMAN
NC score	0.070725 (rank : 724)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	326	Target Neighborhood Hits	1243	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

UFO_HUMAN
NC score	0.070710 (rank : 725)	θ value	θ > 10 (rank : 1202)
Query Neighborhood Hits	326	Target Neighborhood Hits	981	Shared Neighborhood Hits	40
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

EGFR_MOUSE
NC score	0.070708 (rank : 726)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	326	Target Neighborhood Hits	927	Shared Neighborhood Hits	42
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EGFR_HUMAN
NC score	0.070668 (rank : 727)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	326	Target Neighborhood Hits	939	Shared Neighborhood Hits	42
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

RET_HUMAN
NC score	0.070636 (rank : 728)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	326	Target Neighborhood Hits	873	Shared Neighborhood Hits	41
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

SOCS5_MOUSE
NC score	0.070578 (rank : 729)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	326	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	O54928	Gene names	Socs5, Cish5
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5).

ROR2_MOUSE
NC score	0.070451 (rank : 730)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	326	Target Neighborhood Hits	1000	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

INSR_HUMAN
NC score	0.070355 (rank : 731)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	326	Target Neighborhood Hits	963	Shared Neighborhood Hits	41
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

NFH_MOUSE
NC score	0.070329 (rank : 732)	θ value	0.365318 (rank : 121)
Query Neighborhood Hits	326	Target Neighborhood Hits	2247	Shared Neighborhood Hits	154
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RET_MOUSE
NC score	0.070279 (rank : 733)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	326	Target Neighborhood Hits	884	Shared Neighborhood Hits	41
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

TPM3_HUMAN
NC score	0.070088 (rank : 734)	θ value	θ > 10 (rank : 1166)
Query Neighborhood Hits	326	Target Neighborhood Hits	689	Shared Neighborhood Hits	80
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

EPHA1_MOUSE
NC score	0.069958 (rank : 735)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	326	Target Neighborhood Hits	958	Shared Neighborhood Hits	41
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

CT096_HUMAN
NC score	0.069941 (rank : 736)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	326	Target Neighborhood Hits	438	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

UFO_MOUSE
NC score	0.069928 (rank : 737)	θ value	θ > 10 (rank : 1203)
Query Neighborhood Hits	326	Target Neighborhood Hits	988	Shared Neighborhood Hits	40
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

INSR_MOUSE
NC score	0.069884 (rank : 738)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	326	Target Neighborhood Hits	968	Shared Neighborhood Hits	41
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

POF1B_MOUSE
NC score	0.069806 (rank : 739)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	326	Target Neighborhood Hits	530	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

PGFRA_HUMAN
NC score	0.069804 (rank : 740)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	326	Target Neighborhood Hits	980	Shared Neighborhood Hits	44
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_MOUSE
NC score	0.069799 (rank : 741)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	326	Target Neighborhood Hits	960	Shared Neighborhood Hits	42
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRA_MOUSE
NC score	0.069772 (rank : 742)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	326	Target Neighborhood Hits	975	Shared Neighborhood Hits	41
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

CSF1R_MOUSE
NC score	0.069771 (rank : 743)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	326	Target Neighborhood Hits	983	Shared Neighborhood Hits	42
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

RASF8_HUMAN
NC score	0.069715 (rank : 744)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	326	Target Neighborhood Hits	469	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

PGFRB_HUMAN
NC score	0.069610 (rank : 745)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	326	Target Neighborhood Hits	962	Shared Neighborhood Hits	41
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

LMNB2_HUMAN
NC score	0.069600 (rank : 746)	θ value	6.88961 (rank : 293)
Query Neighborhood Hits	326	Target Neighborhood Hits	723	Shared Neighborhood Hits	100
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

MYO6_MOUSE
NC score	0.069560 (rank : 747)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	326	Target Neighborhood Hits	586	Shared Neighborhood Hits	88
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

RON_HUMAN
NC score	0.069519 (rank : 748)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	326	Target Neighborhood Hits	842	Shared Neighborhood Hits	41
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

UBF1_HUMAN
NC score	0.069378 (rank : 749)	θ value	4.03905 (rank : 260)
Query Neighborhood Hits	326	Target Neighborhood Hits	415	Shared Neighborhood Hits	63
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

TNNT2_HUMAN
NC score	0.069274 (rank : 750)	θ value	θ > 10 (rank : 1156)
Query Neighborhood Hits	326	Target Neighborhood Hits	433	Shared Neighborhood Hits	77
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TAOK3_MOUSE
NC score	0.069218 (rank : 751)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	326	Target Neighborhood Hits	1458	Shared Neighborhood Hits	142
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

LMNB1_HUMAN
NC score	0.069216 (rank : 752)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	326	Target Neighborhood Hits	714	Shared Neighborhood Hits	106
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

POF1B_HUMAN
NC score	0.069212 (rank : 753)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	326	Target Neighborhood Hits	494	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

ROR2_HUMAN
NC score	0.069191 (rank : 754)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	326	Target Neighborhood Hits	1014	Shared Neighborhood Hits	43
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

PACN1_MOUSE
NC score	0.069183 (rank : 755)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	326	Target Neighborhood Hits	283	Shared Neighborhood Hits	56
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

EPHA6_HUMAN
NC score	0.069160 (rank : 756)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	326	Target Neighborhood Hits	959	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA6_MOUSE
NC score	0.069142 (rank : 757)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	326	Target Neighborhood Hits	946	Shared Neighborhood Hits	41
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

PACN2_HUMAN
NC score	0.069126 (rank : 758)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	326	Target Neighborhood Hits	339	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

ANR18_HUMAN
NC score	0.069040 (rank : 759)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	326	Target Neighborhood Hits	1106	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

KIF5A_MOUSE
NC score	0.068962 (rank : 760)	θ value	4.03905 (rank : 249)
Query Neighborhood Hits	326	Target Neighborhood Hits	859	Shared Neighborhood Hits	107
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

LIPA3_HUMAN
NC score	0.068960 (rank : 761)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	326	Target Neighborhood Hits	828	Shared Neighborhood Hits	96
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MET_MOUSE
NC score	0.068956 (rank : 762)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	326	Target Neighborhood Hits	844	Shared Neighborhood Hits	41
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

CD2AP_HUMAN
NC score	0.068871 (rank : 763)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	326	Target Neighborhood Hits	315	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

EPHA1_HUMAN
NC score	0.068850 (rank : 764)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	326	Target Neighborhood Hits	997	Shared Neighborhood Hits	41
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

ARI4A_HUMAN
NC score	0.068828 (rank : 765)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	326	Target Neighborhood Hits	434	Shared Neighborhood Hits	67
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

MET_HUMAN
NC score	0.068821 (rank : 766)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	326	Target Neighborhood Hits	831	Shared Neighborhood Hits	41
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

TPM2_HUMAN
NC score	0.068795 (rank : 767)	θ value	θ > 10 (rank : 1164)
Query Neighborhood Hits	326	Target Neighborhood Hits	677	Shared Neighborhood Hits	80
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

M3K11_HUMAN
NC score	0.068690 (rank : 768)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	326	Target Neighborhood Hits	1136	Shared Neighborhood Hits	71
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

TPM3_MOUSE
NC score	0.068687 (rank : 769)	θ value	θ > 10 (rank : 1167)
Query Neighborhood Hits	326	Target Neighborhood Hits	676	Shared Neighborhood Hits	78
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

EPHA5_MOUSE
NC score	0.068628 (rank : 770)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	326	Target Neighborhood Hits	950	Shared Neighborhood Hits	41
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

APOA4_MOUSE
NC score	0.068623 (rank : 771)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	326	Target Neighborhood Hits	435	Shared Neighborhood Hits	65
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

ROR1_MOUSE
NC score	0.068560 (rank : 772)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	326	Target Neighborhood Hits	1025	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR1_HUMAN
NC score	0.068500 (rank : 773)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	326	Target Neighborhood Hits	1018	Shared Neighborhood Hits	43
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

SYGP1_HUMAN
NC score	0.068416 (rank : 774)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	326	Target Neighborhood Hits	589	Shared Neighborhood Hits	99
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

JAK1_MOUSE
NC score	0.068344 (rank : 775)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	326	Target Neighborhood Hits	854	Shared Neighborhood Hits	47
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

FGFR4_MOUSE
NC score	0.068316 (rank : 776)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	326	Target Neighborhood Hits	1026	Shared Neighborhood Hits	41
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

LZTS1_MOUSE
NC score	0.068289 (rank : 777)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	326	Target Neighborhood Hits	540	Shared Neighborhood Hits	72
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

TPM2_MOUSE
NC score	0.068245 (rank : 778)	θ value	θ > 10 (rank : 1165)
Query Neighborhood Hits	326	Target Neighborhood Hits	676	Shared Neighborhood Hits	82
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TYRO3_MOUSE
NC score	0.068245 (rank : 779)	θ value	θ > 10 (rank : 1197)
Query Neighborhood Hits	326	Target Neighborhood Hits	1007	Shared Neighborhood Hits	39
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

TPM4_HUMAN
NC score	0.068206 (rank : 780)	θ value	θ > 10 (rank : 1168)
Query Neighborhood Hits	326	Target Neighborhood Hits	525	Shared Neighborhood Hits	72
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

UBF1_MOUSE
NC score	0.068165 (rank : 781)	θ value	θ > 10 (rank : 1201)
Query Neighborhood Hits	326	Target Neighborhood Hits	419	Shared Neighborhood Hits	65
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

KIF5A_HUMAN
NC score	0.068131 (rank : 782)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	326	Target Neighborhood Hits	843	Shared Neighborhood Hits	107
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

NTRK3_HUMAN
NC score	0.068038 (rank : 783)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	326	Target Neighborhood Hits	1115	Shared Neighborhood Hits	41
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

EPHB6_MOUSE
NC score	0.068025 (rank : 784)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	326	Target Neighborhood Hits	906	Shared Neighborhood Hits	38
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

PLCB3_MOUSE
NC score	0.067985 (rank : 785)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	326	Target Neighborhood Hits	344	Shared Neighborhood Hits	71
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

TYRO3_HUMAN
NC score	0.067963 (rank : 786)	θ value	θ > 10 (rank : 1196)
Query Neighborhood Hits	326	Target Neighborhood Hits	995	Shared Neighborhood Hits	39
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

CCD27_MOUSE
NC score	0.067924 (rank : 787)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	326	Target Neighborhood Hits	461	Shared Neighborhood Hits	68
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

M3K9_HUMAN
NC score	0.067755 (rank : 788)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	326	Target Neighborhood Hits	1123	Shared Neighborhood Hits	77
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

CU013_HUMAN
NC score	0.067612 (rank : 789)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	326	Target Neighborhood Hits	405	Shared Neighborhood Hits	66
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CD2AP_MOUSE
NC score	0.067599 (rank : 790)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	326	Target Neighborhood Hits	336	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

EPHB6_HUMAN
NC score	0.067574 (rank : 791)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	326	Target Neighborhood Hits	912	Shared Neighborhood Hits	37
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

GCP60_HUMAN
NC score	0.067465 (rank : 792)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	326	Target Neighborhood Hits	419	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

TNNT2_MOUSE
NC score	0.067378 (rank : 793)	θ value	θ > 10 (rank : 1157)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	79
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

JAK1_HUMAN
NC score	0.067361 (rank : 794)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	326	Target Neighborhood Hits	858	Shared Neighborhood Hits	46
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

ARHG6_HUMAN
NC score	0.067341 (rank : 795)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	326	Target Neighborhood Hits	376	Shared Neighborhood Hits	62
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

LRSM1_HUMAN
NC score	0.067338 (rank : 796)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	326	Target Neighborhood Hits	1078	Shared Neighborhood Hits	112
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

TTC16_HUMAN
NC score	0.067322 (rank : 797)	θ value	0.813845 (rank : 161)
Query Neighborhood Hits	326	Target Neighborhood Hits	417	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

DREB_MOUSE
NC score	0.067296 (rank : 798)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	326	Target Neighborhood Hits	446	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MLKL_MOUSE
NC score	0.067288 (rank : 799)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	326	Target Neighborhood Hits	707	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

LMNB1_MOUSE
NC score	0.067287 (rank : 800)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	326	Target Neighborhood Hits	719	Shared Neighborhood Hits	106
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

MDN1_HUMAN
NC score	0.067246 (rank : 801)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	326	Target Neighborhood Hits	662	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MLKL_HUMAN
NC score	0.067098 (rank : 802)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	326	Target Neighborhood Hits	600	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

FGFR4_HUMAN
NC score	0.067082 (rank : 803)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	326	Target Neighborhood Hits	1037	Shared Neighborhood Hits	41
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

EPHA2_MOUSE
NC score	0.067080 (rank : 804)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	326	Target Neighborhood Hits	1020	Shared Neighborhood Hits	41
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA2_HUMAN
NC score	0.067052 (rank : 805)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	326	Target Neighborhood Hits	1021	Shared Neighborhood Hits	41
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHB3_MOUSE
NC score	0.066893 (rank : 806)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	326	Target Neighborhood Hits	996	Shared Neighborhood Hits	41
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

MRIP_MOUSE
NC score	0.066830 (rank : 807)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	326	Target Neighborhood Hits	569	Shared Neighborhood Hits	78
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

EPHA8_MOUSE
NC score	0.066823 (rank : 808)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	326	Target Neighborhood Hits	969	Shared Neighborhood Hits	43
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

RAI14_HUMAN
NC score	0.066803 (rank : 809)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	326	Target Neighborhood Hits	1367	Shared Neighborhood Hits	121
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

EPHB3_HUMAN
NC score	0.066794 (rank : 810)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	326	Target Neighborhood Hits	996	Shared Neighborhood Hits	41
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

DZIP1_HUMAN
NC score	0.066742 (rank : 811)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	326	Target Neighborhood Hits	675	Shared Neighborhood Hits	69
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

TXLNG_HUMAN
NC score	0.066716 (rank : 812)	θ value	θ > 10 (rank : 1190)
Query Neighborhood Hits	326	Target Neighborhood Hits	568	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

M3K10_HUMAN
NC score	0.066689 (rank : 813)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	326	Target Neighborhood Hits	1071	Shared Neighborhood Hits	77
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MERL_MOUSE
NC score	0.066675 (rank : 814)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	326	Target Neighborhood Hits	524	Shared Neighborhood Hits	88
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

SPTB2_HUMAN
NC score	0.066664 (rank : 815)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	326	Target Neighborhood Hits	748	Shared Neighborhood Hits	106
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

TRAK2_HUMAN
NC score	0.066589 (rank : 816)	θ value	θ > 10 (rank : 1176)
Query Neighborhood Hits	326	Target Neighborhood Hits	476	Shared Neighborhood Hits	75
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

STMN3_MOUSE
NC score	0.066550 (rank : 817)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	326	Target Neighborhood Hits	331	Shared Neighborhood Hits	83
SwissProt Accessions	O70166	Gene names	Stmn3, Sclip
Domain Architecture
Description	Stathmin-3 (SCG10-like protein) (SCG10-related protein HiAT3) (Hippocampus abundant transcript 3).

ARHG6_MOUSE
NC score	0.066506 (rank : 818)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	326	Target Neighborhood Hits	394	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

SFR11_HUMAN
NC score	0.066452 (rank : 819)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	326	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

EPHA8_HUMAN
NC score	0.066363 (rank : 820)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	326	Target Neighborhood Hits	956	Shared Neighborhood Hits	43
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

MUSK_MOUSE
NC score	0.066330 (rank : 821)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	326	Target Neighborhood Hits	1057	Shared Neighborhood Hits	41
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

AMOL2_HUMAN
NC score	0.066282 (rank : 822)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	326	Target Neighborhood Hits	603	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

EPHB4_HUMAN
NC score	0.066267 (rank : 823)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	326	Target Neighborhood Hits	1056	Shared Neighborhood Hits	41
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

SPTB2_MOUSE
NC score	0.066263 (rank : 824)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	326	Target Neighborhood Hits	770	Shared Neighborhood Hits	107
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

KIF14_HUMAN
NC score	0.066260 (rank : 825)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	326	Target Neighborhood Hits	732	Shared Neighborhood Hits	121
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

NTRK2_MOUSE
NC score	0.066240 (rank : 826)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	326	Target Neighborhood Hits	1088	Shared Neighborhood Hits	41
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK2_HUMAN
NC score	0.066236 (rank : 827)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	326	Target Neighborhood Hits	1081	Shared Neighborhood Hits	41
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

EPHB2_MOUSE
NC score	0.066149 (rank : 828)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	326	Target Neighborhood Hits	982	Shared Neighborhood Hits	41
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB2_HUMAN
NC score	0.066124 (rank : 829)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	326	Target Neighborhood Hits	983	Shared Neighborhood Hits	41
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

SEC20_MOUSE
NC score	0.066072 (rank : 830)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	326	Target Neighborhood Hits	323	Shared Neighborhood Hits	67
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

EPHA4_HUMAN
NC score	0.066049 (rank : 831)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	326	Target Neighborhood Hits	975	Shared Neighborhood Hits	41
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHB4_MOUSE
NC score	0.066028 (rank : 832)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	326	Target Neighborhood Hits	1013	Shared Neighborhood Hits	41
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

MUSK_HUMAN
NC score	0.066023 (rank : 833)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	326	Target Neighborhood Hits	1074	Shared Neighborhood Hits	41
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

EPHA4_MOUSE
NC score	0.066011 (rank : 834)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	326	Target Neighborhood Hits	982	Shared Neighborhood Hits	41
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

JIP3_HUMAN
NC score	0.066002 (rank : 835)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	326	Target Neighborhood Hits	1039	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

HOME2_HUMAN
NC score	0.065802 (rank : 836)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	326	Target Neighborhood Hits	532	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

RGNEF_MOUSE
NC score	0.065789 (rank : 837)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	326	Target Neighborhood Hits	641	Shared Neighborhood Hits	105
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

FGFR2_MOUSE
NC score	0.065786 (rank : 838)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	326	Target Neighborhood Hits	1062	Shared Neighborhood Hits	43
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

EPHA3_MOUSE
NC score	0.065616 (rank : 839)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	326	Target Neighborhood Hits	1009	Shared Neighborhood Hits	41
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHB1_HUMAN
NC score	0.065614 (rank : 840)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	326	Target Neighborhood Hits	988	Shared Neighborhood Hits	41
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

CCD42_MOUSE
NC score	0.065595 (rank : 841)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	326	Target Neighborhood Hits	284	Shared Neighborhood Hits	58
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

EPHA5_HUMAN
NC score	0.065594 (rank : 842)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	326	Target Neighborhood Hits	1009	Shared Neighborhood Hits	41
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

FGFR2_HUMAN
NC score	0.065593 (rank : 843)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	326	Target Neighborhood Hits	1062	Shared Neighborhood Hits	43
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

STAM1_MOUSE
NC score	0.065582 (rank : 844)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	326	Target Neighborhood Hits	273	Shared Neighborhood Hits	37
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CTGE2_HUMAN
NC score	0.065578 (rank : 845)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	326	Target Neighborhood Hits	594	Shared Neighborhood Hits	78
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

FGFR3_HUMAN
NC score	0.065542 (rank : 846)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	326	Target Neighborhood Hits	1042	Shared Neighborhood Hits	41
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

EPHA3_HUMAN
NC score	0.065398 (rank : 847)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	326	Target Neighborhood Hits	1005	Shared Neighborhood Hits	41
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

ESCO1_HUMAN
NC score	0.065364 (rank : 848)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	326	Target Neighborhood Hits	361	Shared Neighborhood Hits	77
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

TXLNG_MOUSE
NC score	0.065336 (rank : 849)	θ value	θ > 10 (rank : 1191)
Query Neighborhood Hits	326	Target Neighborhood Hits	552	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

SELS_HUMAN
NC score	0.065322 (rank : 850)	θ value	0.62314 (rank : 143)
Query Neighborhood Hits	326	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQE4, Q3B771, Q9P0I6	Gene names	SELS, VIMP
Domain Architecture
Description	Selenoprotein S (VCP-interacting membrane protein).

FGFR3_MOUSE
NC score	0.065304 (rank : 851)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	326	Target Neighborhood Hits	1059	Shared Neighborhood Hits	43
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

SH3K1_HUMAN
NC score	0.065303 (rank : 852)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	326	Target Neighborhood Hits	341	Shared Neighborhood Hits	52
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

AMOL2_MOUSE
NC score	0.065164 (rank : 853)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	326	Target Neighborhood Hits	591	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

T3JAM_MOUSE
NC score	0.065124 (rank : 854)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	326	Target Neighborhood Hits	535	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

STAM1_HUMAN
NC score	0.064976 (rank : 855)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	326	Target Neighborhood Hits	271	Shared Neighborhood Hits	37
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

FGFR1_HUMAN
NC score	0.064774 (rank : 856)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	326	Target Neighborhood Hits	1069	Shared Neighborhood Hits	42
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
NC score	0.064746 (rank : 857)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	326	Target Neighborhood Hits	1068	Shared Neighborhood Hits	42
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

TIE1_HUMAN
NC score	0.064740 (rank : 858)	θ value	θ > 10 (rank : 1146)
Query Neighborhood Hits	326	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

SPC25_HUMAN
NC score	0.064717 (rank : 859)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	326	Target Neighborhood Hits	273	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

EPHA7_HUMAN
NC score	0.064688 (rank : 860)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	326	Target Neighborhood Hits	1053	Shared Neighborhood Hits	41
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

MRIP_HUMAN
NC score	0.064657 (rank : 861)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	326	Target Neighborhood Hits	578	Shared Neighborhood Hits	77
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

EPHA7_MOUSE
NC score	0.064643 (rank : 862)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	326	Target Neighborhood Hits	1025	Shared Neighborhood Hits	41
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

TIE1_MOUSE
NC score	0.064502 (rank : 863)	θ value	θ > 10 (rank : 1147)
Query Neighborhood Hits	326	Target Neighborhood Hits	1266	Shared Neighborhood Hits	42
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TAOK2_MOUSE
NC score	0.064429 (rank : 864)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	326	Target Neighborhood Hits	1373	Shared Neighborhood Hits	127
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

GCP60_MOUSE
NC score	0.064424 (rank : 865)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

MYST3_HUMAN
NC score	0.064403 (rank : 866)	θ value	0.813845 (rank : 155)
Query Neighborhood Hits	326	Target Neighborhood Hits	772	Shared Neighborhood Hits	80
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MERL_HUMAN
NC score	0.064367 (rank : 867)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	326	Target Neighborhood Hits	532	Shared Neighborhood Hits	87
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

NSBP1_HUMAN
NC score	0.064306 (rank : 868)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	326	Target Neighborhood Hits	251	Shared Neighborhood Hits	42
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

K0552_HUMAN
NC score	0.064259 (rank : 869)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	326	Target Neighborhood Hits	442	Shared Neighborhood Hits	67
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

GBP4_HUMAN
NC score	0.064243 (rank : 870)	θ value	0.21417 (rank : 105)
Query Neighborhood Hits	326	Target Neighborhood Hits	484	Shared Neighborhood Hits	61
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

JAK3_HUMAN
NC score	0.064167 (rank : 871)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	326	Target Neighborhood Hits	827	Shared Neighborhood Hits	41
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

STXB4_HUMAN
NC score	0.064151 (rank : 872)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	326	Target Neighborhood Hits	616	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TYK2_MOUSE
NC score	0.064065 (rank : 873)	θ value	θ > 10 (rank : 1195)
Query Neighborhood Hits	326	Target Neighborhood Hits	850	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TIE2_HUMAN
NC score	0.063920 (rank : 874)	θ value	θ > 10 (rank : 1148)
Query Neighborhood Hits	326	Target Neighborhood Hits	1192	Shared Neighborhood Hits	40
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

BRAP_HUMAN
NC score	0.063907 (rank : 875)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	326	Target Neighborhood Hits	560	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

PACN1_HUMAN
NC score	0.063862 (rank : 876)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	326	Target Neighborhood Hits	320	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

JAK2_MOUSE
NC score	0.063840 (rank : 877)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	326	Target Neighborhood Hits	839	Shared Neighborhood Hits	43
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

TIE2_MOUSE
NC score	0.063810 (rank : 878)	θ value	θ > 10 (rank : 1149)
Query Neighborhood Hits	326	Target Neighborhood Hits	1204	Shared Neighborhood Hits	40
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

SCG1_MOUSE
NC score	0.063795 (rank : 879)	θ value	0.813845 (rank : 159)
Query Neighborhood Hits	326	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

MMRN1_HUMAN
NC score	0.063601 (rank : 880)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	326	Target Neighborhood Hits	636	Shared Neighborhood Hits	65
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

VGFR3_HUMAN
NC score	0.063572 (rank : 881)	θ value	θ > 10 (rank : 1213)
Query Neighborhood Hits	326	Target Neighborhood Hits	1037	Shared Neighborhood Hits	41
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

TXLNB_HUMAN
NC score	0.063560 (rank : 882)	θ value	θ > 10 (rank : 1188)
Query Neighborhood Hits	326	Target Neighborhood Hits	912	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

PTK7_HUMAN
NC score	0.063450 (rank : 883)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	326	Target Neighborhood Hits	1103	Shared Neighborhood Hits	41
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

JAK2_HUMAN
NC score	0.063422 (rank : 884)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	326	Target Neighborhood Hits	847	Shared Neighborhood Hits	44
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

SURF6_MOUSE
NC score	0.063412 (rank : 885)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	326	Target Neighborhood Hits	195	Shared Neighborhood Hits	40
SwissProt Accessions	P70279, Q8BPI4, Q8BRL7, Q8R0Q7	Gene names	Surf6, Surf-6
Domain Architecture
Description	Surfeit locus protein 6.

JIP3_MOUSE
NC score	0.063411 (rank : 886)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	326	Target Neighborhood Hits	759	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

DMP1_HUMAN
NC score	0.063407 (rank : 887)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	326	Target Neighborhood Hits	491	Shared Neighborhood Hits	63
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

KIF3A_MOUSE
NC score	0.063397 (rank : 888)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	326	Target Neighborhood Hits	715	Shared Neighborhood Hits	114
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

VGFR3_MOUSE
NC score	0.063363 (rank : 889)	θ value	θ > 10 (rank : 1214)
Query Neighborhood Hits	326	Target Neighborhood Hits	1056	Shared Neighborhood Hits	41
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

ARHG7_HUMAN
NC score	0.063305 (rank : 890)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	326	Target Neighborhood Hits	347	Shared Neighborhood Hits	46
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

DNMBP_HUMAN
NC score	0.063241 (rank : 891)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	326	Target Neighborhood Hits	413	Shared Neighborhood Hits	60
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

LMNB2_MOUSE
NC score	0.063208 (rank : 892)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	326	Target Neighborhood Hits	674	Shared Neighborhood Hits	94
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

TYK2_HUMAN
NC score	0.063190 (rank : 893)	θ value	θ > 10 (rank : 1194)
Query Neighborhood Hits	326	Target Neighborhood Hits	841	Shared Neighborhood Hits	41
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

DREB_HUMAN
NC score	0.063154 (rank : 894)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	326	Target Neighborhood Hits	450	Shared Neighborhood Hits	71
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

CAR14_MOUSE
NC score	0.063128 (rank : 895)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	326	Target Neighborhood Hits	526	Shared Neighborhood Hits	81
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

VINEX_HUMAN
NC score	0.063121 (rank : 896)	θ value	θ > 10 (rank : 1217)
Query Neighborhood Hits	326	Target Neighborhood Hits	270	Shared Neighborhood Hits	42
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

NKTR_HUMAN
NC score	0.062937 (rank : 897)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	326	Target Neighborhood Hits	658	Shared Neighborhood Hits	101
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

DYXC1_MOUSE
NC score	0.062781 (rank : 898)	θ value	0.47712 (rank : 130)
Query Neighborhood Hits	326	Target Neighborhood Hits	172	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

SH3K1_MOUSE
NC score	0.062756 (rank : 899)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	326	Target Neighborhood Hits	332	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

STXB4_MOUSE
NC score	0.062685 (rank : 900)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	326	Target Neighborhood Hits	629	Shared Neighborhood Hits	79
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

VGFR2_MOUSE
NC score	0.062673 (rank : 901)	θ value	θ > 10 (rank : 1212)
Query Neighborhood Hits	326	Target Neighborhood Hits	1089	Shared Neighborhood Hits	42
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

ASPP2_HUMAN
NC score	0.062669 (rank : 902)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	326	Target Neighborhood Hits	1156	Shared Neighborhood Hits	105
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

DIAP1_MOUSE
NC score	0.062655 (rank : 903)	θ value	6.88961 (rank : 291)
Query Neighborhood Hits	326	Target Neighborhood Hits	839	Shared Neighborhood Hits	97
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

CCAR1_MOUSE
NC score	0.062628 (rank : 904)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	326	Target Neighborhood Hits	414	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

VGFR2_HUMAN
NC score	0.062600 (rank : 905)	θ value	θ > 10 (rank : 1211)
Query Neighborhood Hits	326	Target Neighborhood Hits	1103	Shared Neighborhood Hits	42
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

HAP1_MOUSE
NC score	0.062567 (rank : 906)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	326	Target Neighborhood Hits	388	Shared Neighborhood Hits	64
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

NUP88_HUMAN
NC score	0.062517 (rank : 907)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	326	Target Neighborhood Hits	354	Shared Neighborhood Hits	77
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

DNMT1_HUMAN
NC score	0.062393 (rank : 908)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	326	Target Neighborhood Hits	401	Shared Neighborhood Hits	86
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

MDC1_HUMAN
NC score	0.062331 (rank : 909)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	326	Target Neighborhood Hits	1446	Shared Neighborhood Hits	116
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

KIF11_HUMAN
NC score	0.062328 (rank : 910)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	326	Target Neighborhood Hits	583	Shared Neighborhood Hits	81
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

ASPP1_HUMAN
NC score	0.062298 (rank : 911)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	326	Target Neighborhood Hits	956	Shared Neighborhood Hits	101
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

DHX16_HUMAN
NC score	0.062170 (rank : 912)	θ value	5.27518 (rank : 265)
Query Neighborhood Hits	326	Target Neighborhood Hits	356	Shared Neighborhood Hits	74
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

JAK3_MOUSE
NC score	0.062113 (rank : 913)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	326	Target Neighborhood Hits	821	Shared Neighborhood Hits	41
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

CHCH3_MOUSE
NC score	0.062089 (rank : 914)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	326	Target Neighborhood Hits	249	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CN044_HUMAN
NC score	0.061989 (rank : 915)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

STAM2_HUMAN
NC score	0.061977 (rank : 916)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	326	Target Neighborhood Hits	288	Shared Neighborhood Hits	39
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAC3_MOUSE
NC score	0.061913 (rank : 917)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	326	Target Neighborhood Hits	232	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

K0831_MOUSE
NC score	0.061807 (rank : 918)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	326	Target Neighborhood Hits	277	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

GP73_HUMAN
NC score	0.061542 (rank : 919)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	326	Target Neighborhood Hits	309	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

CD2L1_HUMAN
NC score	0.061534 (rank : 920)	θ value	0.62314 (rank : 136)
Query Neighborhood Hits	326	Target Neighborhood Hits	1467	Shared Neighborhood Hits	119
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

STAC3_HUMAN
NC score	0.061419 (rank : 921)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	326	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

LBN_HUMAN
NC score	0.061333 (rank : 922)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	326	Target Neighborhood Hits	308	Shared Neighborhood Hits	59
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

DYHC_HUMAN
NC score	0.061311 (rank : 923)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	326	Target Neighborhood Hits	733	Shared Neighborhood Hits	114
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

VGFR1_HUMAN
NC score	0.061307 (rank : 924)	θ value	θ > 10 (rank : 1209)
Query Neighborhood Hits	326	Target Neighborhood Hits	1109	Shared Neighborhood Hits	41
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

GUC2F_HUMAN
NC score	0.061304 (rank : 925)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	326	Target Neighborhood Hits	740	Shared Neighborhood Hits	39
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

VGFR1_MOUSE
NC score	0.061285 (rank : 926)	θ value	θ > 10 (rank : 1210)
Query Neighborhood Hits	326	Target Neighborhood Hits	1118	Shared Neighborhood Hits	41
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

TXND2_HUMAN
NC score	0.061229 (rank : 927)	θ value	θ > 10 (rank : 1192)
Query Neighborhood Hits	326	Target Neighborhood Hits	793	Shared Neighborhood Hits	66
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

APOE_MOUSE
NC score	0.061163 (rank : 928)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	326	Target Neighborhood Hits	319	Shared Neighborhood Hits	53
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

VINEX_MOUSE
NC score	0.061157 (rank : 929)	θ value	θ > 10 (rank : 1218)
Query Neighborhood Hits	326	Target Neighborhood Hits	286	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

STAM2_MOUSE
NC score	0.061147 (rank : 930)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	326	Target Neighborhood Hits	285	Shared Neighborhood Hits	41
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

CD2L2_HUMAN
NC score	0.061067 (rank : 931)	θ value	0.21417 (rank : 102)
Query Neighborhood Hits	326	Target Neighborhood Hits	1439	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

ASPP1_MOUSE
NC score	0.061043 (rank : 932)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	326	Target Neighborhood Hits	1244	Shared Neighborhood Hits	108
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

DYHC_MOUSE
NC score	0.061008 (rank : 933)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	326	Target Neighborhood Hits	729	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

SAFB2_HUMAN
NC score	0.060960 (rank : 934)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	326	Target Neighborhood Hits	720	Shared Neighborhood Hits	92
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

LIPB1_HUMAN
NC score	0.060897 (rank : 935)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	326	Target Neighborhood Hits	640	Shared Neighborhood Hits	80
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

LAD1_MOUSE
NC score	0.060854 (rank : 936)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	326	Target Neighborhood Hits	391	Shared Neighborhood Hits	65
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

CDR2_HUMAN
NC score	0.060852 (rank : 937)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	326	Target Neighborhood Hits	404	Shared Neighborhood Hits	69
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

MYST4_HUMAN
NC score	0.060831 (rank : 938)	θ value	0.62314 (rank : 140)
Query Neighborhood Hits	326	Target Neighborhood Hits	671	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

ILK_MOUSE
NC score	0.060791 (rank : 939)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	326	Target Neighborhood Hits	858	Shared Neighborhood Hits	43
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

TEKT1_HUMAN
NC score	0.060788 (rank : 940)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	326	Target Neighborhood Hits	289	Shared Neighborhood Hits	60
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

ANPRA_MOUSE
NC score	0.060565 (rank : 941)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	326	Target Neighborhood Hits	600	Shared Neighborhood Hits	39
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

REN3A_HUMAN
NC score	0.060554 (rank : 942)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	326	Target Neighborhood Hits	248	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

ANPRA_HUMAN
NC score	0.060552 (rank : 943)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	326	Target Neighborhood Hits	612	Shared Neighborhood Hits	39
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

LZTS1_HUMAN
NC score	0.060513 (rank : 944)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	326	Target Neighborhood Hits	532	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

ENAH_HUMAN
NC score	0.060319 (rank : 945)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	326	Target Neighborhood Hits	784	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

TTC1_HUMAN
NC score	0.060257 (rank : 946)	θ value	θ > 10 (rank : 1179)
Query Neighborhood Hits	326	Target Neighborhood Hits	417	Shared Neighborhood Hits	97
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

SEMG2_HUMAN
NC score	0.060213 (rank : 947)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	326	Target Neighborhood Hits	251	Shared Neighborhood Hits	48
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

THOC2_HUMAN
NC score	0.060144 (rank : 948)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	326	Target Neighborhood Hits	337	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

ILK1_HUMAN
NC score	0.060140 (rank : 949)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	326	Target Neighborhood Hits	857	Shared Neighborhood Hits	43
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

VDP_MOUSE
NC score	0.060044 (rank : 950)	θ value	θ > 10 (rank : 1208)
Query Neighborhood Hits	326	Target Neighborhood Hits	469	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

DNMBP_MOUSE
NC score	0.059916 (rank : 951)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	326	Target Neighborhood Hits	435	Shared Neighborhood Hits	58
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

CD2L1_MOUSE
NC score	0.059846 (rank : 952)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	326	Target Neighborhood Hits	1463	Shared Neighborhood Hits	115
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

OSTF1_HUMAN
NC score	0.059843 (rank : 953)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	326	Target Neighborhood Hits	466	Shared Neighborhood Hits	42
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ILK2_HUMAN
NC score	0.059784 (rank : 954)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	326	Target Neighborhood Hits	848	Shared Neighborhood Hits	43
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

NEBU_HUMAN
NC score	0.059777 (rank : 955)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	326	Target Neighborhood Hits	420	Shared Neighborhood Hits	84
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

AMOT_HUMAN
NC score	0.059719 (rank : 956)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	326	Target Neighborhood Hits	712	Shared Neighborhood Hits	79
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

LMO7_HUMAN
NC score	0.059433 (rank : 957)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	326	Target Neighborhood Hits	507	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

NUCB1_MOUSE
NC score	0.059346 (rank : 958)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	326	Target Neighborhood Hits	414	Shared Neighborhood Hits	81
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

LRSM1_MOUSE
NC score	0.059168 (rank : 959)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	326	Target Neighborhood Hits	874	Shared Neighborhood Hits	90
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

SYCP2_HUMAN
NC score	0.059142 (rank : 960)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	326	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

RASF8_MOUSE
NC score	0.059131 (rank : 961)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	326	Target Neighborhood Hits	391	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

APOA4_HUMAN
NC score	0.058936 (rank : 962)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	326	Target Neighborhood Hits	399	Shared Neighborhood Hits	63
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

TNNT3_HUMAN
NC score	0.058858 (rank : 963)	θ value	θ > 10 (rank : 1158)
Query Neighborhood Hits	326	Target Neighborhood Hits	327	Shared Neighborhood Hits	64
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

MORC3_HUMAN
NC score	0.058780 (rank : 964)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	326	Target Neighborhood Hits	489	Shared Neighborhood Hits	83
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

CCD93_MOUSE
NC score	0.058769 (rank : 965)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	326	Target Neighborhood Hits	362	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

LMNA_MOUSE
NC score	0.058691 (rank : 966)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	326	Target Neighborhood Hits	661	Shared Neighborhood Hits	100
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

PCLO_MOUSE
NC score	0.058630 (rank : 967)	θ value	0.0961366 (rank : 87)
Query Neighborhood Hits	326	Target Neighborhood Hits	2275	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SH3G1_HUMAN
NC score	0.058581 (rank : 968)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

LMNA_HUMAN
NC score	0.058581 (rank : 969)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	326	Target Neighborhood Hits	653	Shared Neighborhood Hits	96
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

SKI_MOUSE
NC score	0.058501 (rank : 970)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	326	Target Neighborhood Hits	423	Shared Neighborhood Hits	82
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

GFAP_HUMAN
NC score	0.058499 (rank : 971)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	326	Target Neighborhood Hits	723	Shared Neighborhood Hits	106
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

NUP88_MOUSE
NC score	0.058348 (rank : 972)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	326	Target Neighborhood Hits	239	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

MYO1E_HUMAN
NC score	0.058264 (rank : 973)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	326	Target Neighborhood Hits	293	Shared Neighborhood Hits	46
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

GFAP_MOUSE
NC score	0.058113 (rank : 974)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	326	Target Neighborhood Hits	725	Shared Neighborhood Hits	99
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

MLTK_MOUSE
NC score	0.058064 (rank : 975)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	326	Target Neighborhood Hits	874	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

DEK_MOUSE
NC score	0.057951 (rank : 976)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	326	Target Neighborhood Hits	280	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

TAF4_HUMAN
NC score	0.057870 (rank : 977)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	326	Target Neighborhood Hits	687	Shared Neighborhood Hits	79
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MLTK_HUMAN
NC score	0.057867 (rank : 978)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	326	Target Neighborhood Hits	911	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

KIF3A_HUMAN
NC score	0.057753 (rank : 979)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	326	Target Neighborhood Hits	704	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

TTF1_MOUSE
NC score	0.057679 (rank : 980)	θ value	θ > 10 (rank : 1181)
Query Neighborhood Hits	326	Target Neighborhood Hits	277	Shared Neighborhood Hits	69
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

OSTF1_MOUSE
NC score	0.057652 (rank : 981)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	326	Target Neighborhood Hits	467	Shared Neighborhood Hits	42
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

SKI_HUMAN
NC score	0.057624 (rank : 982)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	326	Target Neighborhood Hits	423	Shared Neighborhood Hits	79
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

SH3G1_MOUSE
NC score	0.057518 (rank : 983)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	326	Target Neighborhood Hits	291	Shared Neighborhood Hits	56
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

CAR14_HUMAN
NC score	0.057508 (rank : 984)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	326	Target Neighborhood Hits	449	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

RRP5_HUMAN
NC score	0.057455 (rank : 985)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	326	Target Neighborhood Hits	291	Shared Neighborhood Hits	77
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

MPP10_HUMAN
NC score	0.057429 (rank : 986)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	326	Target Neighborhood Hits	306	Shared Neighborhood Hits	61
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

AFF4_HUMAN
NC score	0.057426 (rank : 987)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	326	Target Neighborhood Hits	611	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

RBMX2_MOUSE
NC score	0.057398 (rank : 988)	θ value	2.36792 (rank : 215)
Query Neighborhood Hits	326	Target Neighborhood Hits	287	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

SDS3_HUMAN
NC score	0.057395 (rank : 989)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	326	Target Neighborhood Hits	257	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SRC8_MOUSE
NC score	0.057380 (rank : 990)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	326	Target Neighborhood Hits	292	Shared Neighborhood Hits	48
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

NCF1_MOUSE
NC score	0.057350 (rank : 991)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	326	Target Neighborhood Hits	198	Shared Neighborhood Hits	34
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

SRC8_HUMAN
NC score	0.057348 (rank : 992)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	326	Target Neighborhood Hits	269	Shared Neighborhood Hits	47
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SELS_MOUSE
NC score	0.057297 (rank : 993)	θ value	2.36792 (rank : 217)
Query Neighborhood Hits	326	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BCZ4, Q921S1, Q9DB55	Gene names	Sels, H47, Vimp
Domain Architecture
Description	Selenoprotein S (VCP-interacting membrane protein) (Minor histocompatibility antigen H47).

NUCB1_HUMAN
NC score	0.057294 (rank : 994)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	326	Target Neighborhood Hits	359	Shared Neighborhood Hits	83
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

TXLNB_MOUSE
NC score	0.057290 (rank : 995)	θ value	θ > 10 (rank : 1189)
Query Neighborhood Hits	326	Target Neighborhood Hits	640	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

RIPK1_MOUSE
NC score	0.057276 (rank : 996)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	326	Target Neighborhood Hits	874	Shared Neighborhood Hits	46
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ARAF_HUMAN
NC score	0.057246 (rank : 997)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	326	Target Neighborhood Hits	924	Shared Neighborhood Hits	45
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

AL2SB_HUMAN
NC score	0.057220 (rank : 998)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	326	Target Neighborhood Hits	294	Shared Neighborhood Hits	50
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

ARAF_MOUSE
NC score	0.057201 (rank : 999)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	326	Target Neighborhood Hits	874	Shared Neighborhood Hits	44
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

POT15_HUMAN
NC score	0.057171 (rank : 1000)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	326	Target Neighborhood Hits	893	Shared Neighborhood Hits	134
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

RAF1_HUMAN
NC score	0.057108 (rank : 1001)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	326	Target Neighborhood Hits	886	Shared Neighborhood Hits	46
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

LBN_MOUSE
NC score	0.057088 (rank : 1002)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	326	Target Neighborhood Hits	310	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

ZN318_HUMAN
NC score	0.057075 (rank : 1003)	θ value	θ > 10 (rank : 1227)
Query Neighborhood Hits	326	Target Neighborhood Hits	497	Shared Neighborhood Hits	96
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

STAC_MOUSE
NC score	0.057044 (rank : 1004)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	326	Target Neighborhood Hits	268	Shared Neighborhood Hits	36
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

NCF1_HUMAN
NC score	0.057031 (rank : 1005)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	326	Target Neighborhood Hits	198	Shared Neighborhood Hits	33
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

SOCS4_MOUSE
NC score	0.057021 (rank : 1006)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	326	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZA6	Gene names	Socs4, Socs7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

CCNB3_HUMAN
NC score	0.057011 (rank : 1007)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	326	Target Neighborhood Hits	368	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

BRAF1_HUMAN
NC score	0.057000 (rank : 1008)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	326	Target Neighborhood Hits	883	Shared Neighborhood Hits	46
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

RAF1_MOUSE
NC score	0.056873 (rank : 1009)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	326	Target Neighborhood Hits	886	Shared Neighborhood Hits	46
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

PCLO_HUMAN
NC score	0.056856 (rank : 1010)	θ value	6.88961 (rank : 295)
Query Neighborhood Hits	326	Target Neighborhood Hits	2046	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RHG25_HUMAN
NC score	0.056837 (rank : 1011)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	326	Target Neighborhood Hits	550	Shared Neighborhood Hits	82
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MYO1F_MOUSE
NC score	0.056760 (rank : 1012)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	326	Target Neighborhood Hits	262	Shared Neighborhood Hits	46
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

ANPRB_MOUSE
NC score	0.056740 (rank : 1013)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	326	Target Neighborhood Hits	607	Shared Neighborhood Hits	43
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

RPTN_MOUSE
NC score	0.056731 (rank : 1014)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	326	Target Neighborhood Hits	650	Shared Neighborhood Hits	85
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

MOS_HUMAN
NC score	0.056682 (rank : 1015)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	326	Target Neighborhood Hits	829	Shared Neighborhood Hits	41
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

ANPRB_HUMAN
NC score	0.056632 (rank : 1016)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	326	Target Neighborhood Hits	646	Shared Neighborhood Hits	43
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

MYO3A_HUMAN
NC score	0.056557 (rank : 1017)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	326	Target Neighborhood Hits	1033	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

M4K4_MOUSE
NC score	0.056555 (rank : 1018)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	326	Target Neighborhood Hits	1560	Shared Neighborhood Hits	131
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MPP10_MOUSE
NC score	0.056554 (rank : 1019)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	326	Target Neighborhood Hits	251	Shared Neighborhood Hits	57
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MYO1F_HUMAN
NC score	0.056540 (rank : 1020)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	326	Target Neighborhood Hits	275	Shared Neighborhood Hits	46
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

TAD3L_MOUSE
NC score	0.056444 (rank : 1021)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	326	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

LC7L2_HUMAN
NC score	0.056328 (rank : 1022)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	326	Target Neighborhood Hits	235	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

CS029_MOUSE
NC score	0.056316 (rank : 1023)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	326	Target Neighborhood Hits	201	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

K0586_HUMAN
NC score	0.056310 (rank : 1024)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	326	Target Neighborhood Hits	311	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

STIM2_HUMAN
NC score	0.056270 (rank : 1025)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	326	Target Neighborhood Hits	420	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

GUC2C_HUMAN
NC score	0.056253 (rank : 1026)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	326	Target Neighborhood Hits	624	Shared Neighborhood Hits	35
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

PPIP2_MOUSE
NC score	0.056251 (rank : 1027)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	326	Target Neighborhood Hits	308	Shared Neighborhood Hits	79
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

LC7L2_MOUSE
NC score	0.056228 (rank : 1028)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	326	Target Neighborhood Hits	244	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

LIPA3_MOUSE
NC score	0.056187 (rank : 1029)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	326	Target Neighborhood Hits	636	Shared Neighborhood Hits	82
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

BAP29_MOUSE
NC score	0.056177 (rank : 1030)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	326	Target Neighborhood Hits	285	Shared Neighborhood Hits	60
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

IMMT_MOUSE
NC score	0.056084 (rank : 1031)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	326	Target Neighborhood Hits	326	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

ENAH_MOUSE
NC score	0.056080 (rank : 1032)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	326	Target Neighborhood Hits	919	Shared Neighborhood Hits	81
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

IRAK1_MOUSE
NC score	0.056069 (rank : 1033)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	326	Target Neighborhood Hits	784	Shared Neighborhood Hits	42
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

STIM2_MOUSE
NC score	0.055995 (rank : 1034)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	326	Target Neighborhood Hits	403	Shared Neighborhood Hits	90
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

RIPK1_HUMAN
NC score	0.055965 (rank : 1035)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	326	Target Neighborhood Hits	891	Shared Neighborhood Hits	44
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ABI2_HUMAN
NC score	0.055948 (rank : 1036)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	326	Target Neighborhood Hits	350	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

PHF3_HUMAN
NC score	0.055942 (rank : 1037)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	326	Target Neighborhood Hits	419	Shared Neighborhood Hits	68
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

HOME1_MOUSE
NC score	0.055877 (rank : 1038)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	326	Target Neighborhood Hits	630	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

IGB1B_MOUSE
NC score	0.055811 (rank : 1039)	θ value	0.21417 (rank : 106)
Query Neighborhood Hits	326	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZ29	Gene names	Igbp1b
Domain Architecture
Description	Immunoglobulin-binding protein 1b (CD79a-binding protein 1b) (Alpha 4- b protein) (Alpha4-b).

SOCS4_HUMAN
NC score	0.055804 (rank : 1040)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	326	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXH5	Gene names	SOCS4, SOCS7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

STX12_MOUSE
NC score	0.055778 (rank : 1041)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	326	Target Neighborhood Hits	283	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

RAB3I_HUMAN
NC score	0.055645 (rank : 1042)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	326	Target Neighborhood Hits	270	Shared Neighborhood Hits	61
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

TAD3L_HUMAN
NC score	0.055607 (rank : 1043)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	326	Target Neighborhood Hits	189	Shared Neighborhood Hits	57
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

K0494_HUMAN
NC score	0.055568 (rank : 1044)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	326	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

SDS3_MOUSE
NC score	0.055549 (rank : 1045)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	326	Target Neighborhood Hits	248	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

MOS_MOUSE
NC score	0.055536 (rank : 1046)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	326	Target Neighborhood Hits	833	Shared Neighborhood Hits	42
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

KI21B_MOUSE
NC score	0.055523 (rank : 1047)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	326	Target Neighborhood Hits	997	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

TNIK_HUMAN
NC score	0.055511 (rank : 1048)	θ value	θ > 10 (rank : 1152)
Query Neighborhood Hits	326	Target Neighborhood Hits	1570	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

M3K12_MOUSE
NC score	0.055510 (rank : 1049)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	326	Target Neighborhood Hits	957	Shared Neighborhood Hits	48
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

ABTAP_HUMAN
NC score	0.055483 (rank : 1050)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	326	Target Neighborhood Hits	290	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

KSR2_HUMAN
NC score	0.055442 (rank : 1051)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	326	Target Neighborhood Hits	920	Shared Neighborhood Hits	42
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

M3K13_HUMAN
NC score	0.055437 (rank : 1052)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	326	Target Neighborhood Hits	911	Shared Neighborhood Hits	44
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

CCAR1_HUMAN
NC score	0.055355 (rank : 1053)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	326	Target Neighborhood Hits	444	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CLC4F_HUMAN
NC score	0.055339 (rank : 1054)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	326	Target Neighborhood Hits	513	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

KSR1_HUMAN
NC score	0.055233 (rank : 1055)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	326	Target Neighborhood Hits	867	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

M3K12_HUMAN
NC score	0.055176 (rank : 1056)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	326	Target Neighborhood Hits	940	Shared Neighborhood Hits	45
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

HCLS1_MOUSE
NC score	0.055106 (rank : 1057)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	326	Target Neighborhood Hits	329	Shared Neighborhood Hits	42
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

BAZ2B_HUMAN
NC score	0.055078 (rank : 1058)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	326	Target Neighborhood Hits	803	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MMRN2_HUMAN
NC score	0.054810 (rank : 1059)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	326	Target Neighborhood Hits	400	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

KIFC3_MOUSE
NC score	0.054597 (rank : 1060)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	326	Target Neighborhood Hits	571	Shared Neighborhood Hits	81
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KI21B_HUMAN
NC score	0.054555 (rank : 1061)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	326	Target Neighborhood Hits	1017	Shared Neighborhood Hits	104
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

NEK11_HUMAN
NC score	0.054523 (rank : 1062)	θ value	8.99809 (rank : 321)
Query Neighborhood Hits	326	Target Neighborhood Hits	1043	Shared Neighborhood Hits	94
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

M4K4_HUMAN
NC score	0.054502 (rank : 1063)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	326	Target Neighborhood Hits	1589	Shared Neighborhood Hits	128
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

NOL10_HUMAN
NC score	0.054496 (rank : 1064)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	326	Target Neighborhood Hits	254	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

STAC_HUMAN
NC score	0.054479 (rank : 1065)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	326	Target Neighborhood Hits	276	Shared Neighborhood Hits	39
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

BRD4_MOUSE
NC score	0.054475 (rank : 1066)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	326	Target Neighborhood Hits	845	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

TS101_HUMAN
NC score	0.054429 (rank : 1067)	θ value	θ > 10 (rank : 1177)
Query Neighborhood Hits	326	Target Neighborhood Hits	359	Shared Neighborhood Hits	66
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

KSR1_MOUSE
NC score	0.054401 (rank : 1068)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	326	Target Neighborhood Hits	870	Shared Neighborhood Hits	43
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

ABI3_HUMAN
NC score	0.054363 (rank : 1069)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

TR150_HUMAN
NC score	0.054189 (rank : 1070)	θ value	θ > 10 (rank : 1171)
Query Neighborhood Hits	326	Target Neighborhood Hits	313	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

KIFC3_HUMAN
NC score	0.054123 (rank : 1071)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	326	Target Neighborhood Hits	619	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

M3K7_MOUSE
NC score	0.053901 (rank : 1072)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	326	Target Neighborhood Hits	892	Shared Neighborhood Hits	54
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

ABI2_MOUSE
NC score	0.053900 (rank : 1073)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	326	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

M3K7_HUMAN
NC score	0.053886 (rank : 1074)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	326	Target Neighborhood Hits	892	Shared Neighborhood Hits	54
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

BAZ2A_HUMAN
NC score	0.053783 (rank : 1075)	θ value	1.06291 (rank : 162)
Query Neighborhood Hits	326	Target Neighborhood Hits	780	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CTR9_MOUSE
NC score	0.053764 (rank : 1076)	θ value	1.81305 (rank : 196)
Query Neighborhood Hits	326	Target Neighborhood Hits	427	Shared Neighborhood Hits	54
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

RIPK2_MOUSE
NC score	0.053756 (rank : 1077)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	326	Target Neighborhood Hits	776	Shared Neighborhood Hits	39
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

PKHA5_HUMAN
NC score	0.053682 (rank : 1078)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	326	Target Neighborhood Hits	455	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RNF8_MOUSE
NC score	0.053619 (rank : 1079)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	326	Target Neighborhood Hits	618	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SH3G2_HUMAN
NC score	0.053468 (rank : 1080)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	326	Target Neighborhood Hits	324	Shared Neighborhood Hits	51
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

TESK2_HUMAN
NC score	0.053384 (rank : 1081)	θ value	θ > 10 (rank : 1139)
Query Neighborhood Hits	326	Target Neighborhood Hits	851	Shared Neighborhood Hits	44
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

SRRM2_MOUSE
NC score	0.053310 (rank : 1082)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	326	Target Neighborhood Hits	1470	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BMR1B_HUMAN
NC score	0.053225 (rank : 1083)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	326	Target Neighborhood Hits	760	Shared Neighborhood Hits	39
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

PHLB1_MOUSE
NC score	0.053185 (rank : 1084)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	326	Target Neighborhood Hits	678	Shared Neighborhood Hits	69
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

T2FA_HUMAN
NC score	0.053179 (rank : 1085)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	326	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

BCLF1_MOUSE
NC score	0.053138 (rank : 1086)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	326	Target Neighborhood Hits	303	Shared Neighborhood Hits	66
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

AMOL1_HUMAN
NC score	0.053067 (rank : 1087)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	326	Target Neighborhood Hits	435	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

IRAK1_HUMAN
NC score	0.053040 (rank : 1088)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	326	Target Neighborhood Hits	820	Shared Neighborhood Hits	41
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

AHI1_HUMAN
NC score	0.053038 (rank : 1089)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	326	Target Neighborhood Hits	537	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

BMR1B_MOUSE
NC score	0.052986 (rank : 1090)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	326	Target Neighborhood Hits	758	Shared Neighborhood Hits	39
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

TTC3_HUMAN
NC score	0.052969 (rank : 1091)	θ value	θ > 10 (rank : 1180)
Query Neighborhood Hits	326	Target Neighborhood Hits	664	Shared Neighborhood Hits	80
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TOPK_HUMAN
NC score	0.052963 (rank : 1092)	θ value	θ > 10 (rank : 1160)
Query Neighborhood Hits	326	Target Neighborhood Hits	605	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

TAOK2_HUMAN
NC score	0.052895 (rank : 1093)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	326	Target Neighborhood Hits	1172	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

LRRF1_MOUSE
NC score	0.052886 (rank : 1094)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	326	Target Neighborhood Hits	440	Shared Neighborhood Hits	71
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

CN045_HUMAN
NC score	0.052874 (rank : 1095)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	44
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

HM20A_MOUSE
NC score	0.052810 (rank : 1096)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	326	Target Neighborhood Hits	348	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

ANR21_HUMAN
NC score	0.052790 (rank : 1097)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	326	Target Neighborhood Hits	864	Shared Neighborhood Hits	132
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

VIME_MOUSE
NC score	0.052767 (rank : 1098)	θ value	θ > 10 (rank : 1216)
Query Neighborhood Hits	326	Target Neighborhood Hits	716	Shared Neighborhood Hits	97
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

ING2_HUMAN
NC score	0.052702 (rank : 1099)	θ value	1.81305 (rank : 199)
Query Neighborhood Hits	326	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

SSNA1_MOUSE
NC score	0.052688 (rank : 1100)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	326	Target Neighborhood Hits	182	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JJ94	Gene names	Ssna1
Domain Architecture	No domain graphic available
Description	Sjoegren syndrome nuclear autoantigen 1 homolog.

LZTS2_HUMAN
NC score	0.052529 (rank : 1101)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	326	Target Neighborhood Hits	427	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

TOPK_MOUSE
NC score	0.052528 (rank : 1102)	θ value	θ > 10 (rank : 1161)
Query Neighborhood Hits	326	Target Neighborhood Hits	618	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

NBN_HUMAN
NC score	0.052469 (rank : 1103)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	326	Target Neighborhood Hits	226	Shared Neighborhood Hits	59
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

SEC63_MOUSE
NC score	0.052469 (rank : 1104)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	326	Target Neighborhood Hits	601	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_HUMAN
NC score	0.052426 (rank : 1105)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	326	Target Neighborhood Hits	586	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

PRP4B_HUMAN
NC score	0.052335 (rank : 1106)	θ value	0.813845 (rank : 157)
Query Neighborhood Hits	326	Target Neighborhood Hits	1030	Shared Neighborhood Hits	86
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

VIME_HUMAN
NC score	0.052301 (rank : 1107)	θ value	θ > 10 (rank : 1215)
Query Neighborhood Hits	326	Target Neighborhood Hits	706	Shared Neighborhood Hits	94
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

PRP4B_MOUSE
NC score	0.052215 (rank : 1108)	θ value	4.03905 (rank : 257)
Query Neighborhood Hits	326	Target Neighborhood Hits	1040	Shared Neighborhood Hits	87
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

HC127_HUMAN
NC score	0.052100 (rank : 1109)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	326	Target Neighborhood Hits	292	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
NC score	0.052100 (rank : 1110)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	326	Target Neighborhood Hits	292	Shared Neighborhood Hits	60
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

GUC2E_MOUSE
NC score	0.052065 (rank : 1111)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	326	Target Neighborhood Hits	692	Shared Neighborhood Hits	39
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

NALP5_MOUSE
NC score	0.052058 (rank : 1112)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	326	Target Neighborhood Hits	560	Shared Neighborhood Hits	107
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

TESK1_HUMAN
NC score	0.052043 (rank : 1113)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	326	Target Neighborhood Hits	864	Shared Neighborhood Hits	46
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TLK2_MOUSE
NC score	0.052024 (rank : 1114)	θ value	θ > 10 (rank : 1151)
Query Neighborhood Hits	326	Target Neighborhood Hits	1088	Shared Neighborhood Hits	118
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

BCN1_HUMAN
NC score	0.051961 (rank : 1115)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	326	Target Neighborhood Hits	395	Shared Neighborhood Hits	67
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

SRGP1_HUMAN
NC score	0.051909 (rank : 1116)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	326	Target Neighborhood Hits	390	Shared Neighborhood Hits	81
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

HM20A_HUMAN
NC score	0.051820 (rank : 1117)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	326	Target Neighborhood Hits	343	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

RIPK3_HUMAN
NC score	0.051781 (rank : 1118)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	326	Target Neighborhood Hits	828	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

RIPK2_HUMAN
NC score	0.051767 (rank : 1119)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	326	Target Neighborhood Hits	774	Shared Neighborhood Hits	39
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

SPC25_MOUSE
NC score	0.051764 (rank : 1120)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	326	Target Neighborhood Hits	241	Shared Neighborhood Hits	52
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

TESK2_MOUSE
NC score	0.051724 (rank : 1121)	θ value	θ > 10 (rank : 1140)
Query Neighborhood Hits	326	Target Neighborhood Hits	833	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

CJ049_HUMAN
NC score	0.051715 (rank : 1122)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	326	Target Neighborhood Hits	90	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

RBP1_HUMAN
NC score	0.051700 (rank : 1123)	θ value	5.27518 (rank : 277)
Query Neighborhood Hits	326	Target Neighborhood Hits	521	Shared Neighborhood Hits	68
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

TESK1_MOUSE
NC score	0.051692 (rank : 1124)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	326	Target Neighborhood Hits	862	Shared Neighborhood Hits	42
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

BMR1A_MOUSE
NC score	0.051616 (rank : 1125)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	326	Target Neighborhood Hits	758	Shared Neighborhood Hits	39
SwissProt Accessions	P36895	Gene names	Bmpr1a, Acvrlk3, Bmpr
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor).

BMR1A_HUMAN
NC score	0.051616 (rank : 1126)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	326	Target Neighborhood Hits	759	Shared Neighborhood Hits	39
SwissProt Accessions	P36894, Q8NEN8	Gene names	BMPR1A, ACVRLK3, ALK3
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen).

NCF2_HUMAN
NC score	0.051578 (rank : 1127)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	326	Target Neighborhood Hits	229	Shared Neighborhood Hits	36
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

AHI1_MOUSE
NC score	0.051519 (rank : 1128)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	326	Target Neighborhood Hits	496	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

IRAK3_HUMAN
NC score	0.051518 (rank : 1129)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	326	Target Neighborhood Hits	644	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

SYCP3_HUMAN
NC score	0.051499 (rank : 1130)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	326	Target Neighborhood Hits	276	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

NPHP3_MOUSE
NC score	0.051409 (rank : 1131)	θ value	5.27518 (rank : 272)
Query Neighborhood Hits	326	Target Neighborhood Hits	335	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

MINK1_HUMAN
NC score	0.051348 (rank : 1132)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	326	Target Neighborhood Hits	1477	Shared Neighborhood Hits	114
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

SPTB1_MOUSE
NC score	0.051275 (rank : 1133)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	326	Target Neighborhood Hits	543	Shared Neighborhood Hits	81
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

CIR_MOUSE
NC score	0.051223 (rank : 1134)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	326	Target Neighborhood Hits	255	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

DBNL_HUMAN
NC score	0.051222 (rank : 1135)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	326	Target Neighborhood Hits	244	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

GUC2D_HUMAN
NC score	0.051213 (rank : 1136)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	326	Target Neighborhood Hits	715	Shared Neighborhood Hits	40
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

CLUA1_MOUSE
NC score	0.051209 (rank : 1137)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	326	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

LIMK1_HUMAN
NC score	0.051193 (rank : 1138)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	326	Target Neighborhood Hits	1005	Shared Neighborhood Hits	43
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK1_MOUSE
NC score	0.051151 (rank : 1139)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	326	Target Neighborhood Hits	1008	Shared Neighborhood Hits	43
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

IRAK3_MOUSE
NC score	0.051124 (rank : 1140)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	326	Target Neighborhood Hits	628	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

HCLS1_HUMAN
NC score	0.051095 (rank : 1141)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	326	Target Neighborhood Hits	358	Shared Neighborhood Hits	36
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

IRAK4_HUMAN
NC score	0.051054 (rank : 1142)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	326	Target Neighborhood Hits	816	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

GBP1_HUMAN
NC score	0.051045 (rank : 1143)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	326	Target Neighborhood Hits	339	Shared Neighborhood Hits	65
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

SEC20_HUMAN
NC score	0.050946 (rank : 1144)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	326	Target Neighborhood Hits	200	Shared Neighborhood Hits	42
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

NEK1_MOUSE
NC score	0.050941 (rank : 1145)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	326	Target Neighborhood Hits	1311	Shared Neighborhood Hits	135
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

MINK1_MOUSE
NC score	0.050927 (rank : 1146)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	326	Target Neighborhood Hits	1451	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

CCD50_MOUSE
NC score	0.050926 (rank : 1147)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	326	Target Neighborhood Hits	172	Shared Neighborhood Hits	48
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

FNBP2_HUMAN
NC score	0.050899 (rank : 1148)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	326	Target Neighborhood Hits	432	Shared Neighborhood Hits	76
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RNF8_HUMAN
NC score	0.050819 (rank : 1149)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	326	Target Neighborhood Hits	622	Shared Neighborhood Hits	65
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

ZCPW1_MOUSE
NC score	0.050746 (rank : 1150)	θ value	θ > 10 (rank : 1226)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	57
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

NUCB2_MOUSE
NC score	0.050671 (rank : 1151)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	326	Target Neighborhood Hits	459	Shared Neighborhood Hits	77
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

YO11_MOUSE
NC score	0.050589 (rank : 1152)	θ value	θ > 10 (rank : 1224)
Query Neighborhood Hits	326	Target Neighborhood Hits	272	Shared Neighborhood Hits	53
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

DBNL_MOUSE
NC score	0.050577 (rank : 1153)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	326	Target Neighborhood Hits	306	Shared Neighborhood Hits	47
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

NPHP3_HUMAN
NC score	0.050541 (rank : 1154)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	326	Target Neighborhood Hits	304	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

BCN1_MOUSE
NC score	0.050454 (rank : 1155)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	326	Target Neighborhood Hits	367	Shared Neighborhood Hits	65
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

ABI3_MOUSE
NC score	0.050446 (rank : 1156)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	326	Target Neighborhood Hits	227	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CENPU_HUMAN
NC score	0.050410 (rank : 1157)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	326	Target Neighborhood Hits	289	Shared Neighborhood Hits	56
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

LIMK2_MOUSE
NC score	0.050404 (rank : 1158)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	326	Target Neighborhood Hits	998	Shared Neighborhood Hits	44
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

T2_MOUSE
NC score	0.050345 (rank : 1159)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	326	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

APOA1_MOUSE
NC score	0.050342 (rank : 1160)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	326	Target Neighborhood Hits	210	Shared Neighborhood Hits	44
SwissProt Accessions	Q00623	Gene names	Apoa1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I).

LIPB2_HUMAN
NC score	0.050329 (rank : 1161)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	326	Target Neighborhood Hits	599	Shared Neighborhood Hits	77
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

PHLB3_HUMAN
NC score	0.050183 (rank : 1162)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	326	Target Neighborhood Hits	304	Shared Neighborhood Hits	49
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

FA50A_MOUSE
NC score	0.050104 (rank : 1163)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	326	Target Neighborhood Hits	293	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

SH3G3_MOUSE
NC score	0.050102 (rank : 1164)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	326	Target Neighborhood Hits	236	Shared Neighborhood Hits	42
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

BPTF_HUMAN
NC score	0.050047 (rank : 1165)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	326	Target Neighborhood Hits	786	Shared Neighborhood Hits	89
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD4_HUMAN
NC score	0.050021 (rank : 1166)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	326	Target Neighborhood Hits	851	Shared Neighborhood Hits	87
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

DIAP1_HUMAN
NC score	0.049853 (rank : 1167)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	326	Target Neighborhood Hits	784	Shared Neighborhood Hits	81
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

RU17_HUMAN
NC score	0.049329 (rank : 1168)	θ value	1.38821 (rank : 188)
Query Neighborhood Hits	326	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

NEK11_MOUSE
NC score	0.048117 (rank : 1169)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	326	Target Neighborhood Hits	875	Shared Neighborhood Hits	46
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

RU17_MOUSE
NC score	0.047573 (rank : 1170)	θ value	1.81305 (rank : 205)
Query Neighborhood Hits	326	Target Neighborhood Hits	278	Shared Neighborhood Hits	25
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

DAXX_HUMAN
NC score	0.047351 (rank : 1171)	θ value	4.03905 (rank : 242)
Query Neighborhood Hits	326	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

EXOC5_HUMAN
NC score	0.047287 (rank : 1172)	θ value	4.03905 (rank : 245)
Query Neighborhood Hits	326	Target Neighborhood Hits	194	Shared Neighborhood Hits	44
SwissProt Accessions	O00471	Gene names	EXOC5, SEC10, SEC10L1
Domain Architecture
Description	Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10).

SON_MOUSE
NC score	0.045408 (rank : 1173)	θ value	4.03905 (rank : 258)
Query Neighborhood Hits	326	Target Neighborhood Hits	957	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

PHF14_HUMAN
NC score	0.045391 (rank : 1174)	θ value	5.27518 (rank : 274)
Query Neighborhood Hits	326	Target Neighborhood Hits	447	Shared Neighborhood Hits	67
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

SON_HUMAN
NC score	0.043476 (rank : 1175)	θ value	0.163984 (rank : 100)
Query Neighborhood Hits	326	Target Neighborhood Hits	1568	Shared Neighborhood Hits	63
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MYT1_HUMAN
NC score	0.043134 (rank : 1176)	θ value	1.81305 (rank : 200)
Query Neighborhood Hits	326	Target Neighborhood Hits	475	Shared Neighborhood Hits	64
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

SEC62_HUMAN
NC score	0.042920 (rank : 1177)	θ value	5.27518 (rank : 279)
Query Neighborhood Hits	326	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

ING2_MOUSE
NC score	0.041661 (rank : 1178)	θ value	4.03905 (rank : 246)
Query Neighborhood Hits	326	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

IGBP1_HUMAN
NC score	0.041009 (rank : 1179)	θ value	3.0926 (rank : 230)
Query Neighborhood Hits	326	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	P78318, Q8TAB2	Gene names	IGBP1
Domain Architecture
Description	Immunoglobulin-binding protein 1 (CD79a-binding protein 1) (B cell signal transduction molecule alpha 4) (Alpha 4 protein) (NY-REN-16 antigen).

BRDT_MOUSE
NC score	0.039124 (rank : 1180)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	326	Target Neighborhood Hits	243	Shared Neighborhood Hits	46
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

SEP11_MOUSE
NC score	0.037941 (rank : 1181)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	326	Target Neighborhood Hits	300	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

PRGC2_HUMAN
NC score	0.037639 (rank : 1182)	θ value	1.38821 (rank : 185)
Query Neighborhood Hits	326	Target Neighborhood Hits	272	Shared Neighborhood Hits	14
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

MYPT1_HUMAN
NC score	0.035647 (rank : 1183)	θ value	5.27518 (rank : 271)
Query Neighborhood Hits	326	Target Neighborhood Hits	723	Shared Neighborhood Hits	89
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

DIDO1_HUMAN
NC score	0.034956 (rank : 1184)	θ value	4.03905 (rank : 243)
Query Neighborhood Hits	326	Target Neighborhood Hits	960	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ARS2_MOUSE
NC score	0.034663 (rank : 1185)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	326	Target Neighborhood Hits	212	Shared Neighborhood Hits	26
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

SEP11_HUMAN
NC score	0.034406 (rank : 1186)	θ value	2.36792 (rank : 218)
Query Neighborhood Hits	326	Target Neighborhood Hits	296	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

EST1A_MOUSE
NC score	0.034328 (rank : 1187)	θ value	3.0926 (rank : 228)
Query Neighborhood Hits	326	Target Neighborhood Hits	138	Shared Neighborhood Hits	30
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

DAXX_MOUSE
NC score	0.033750 (rank : 1188)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	326	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

NOG1_HUMAN
NC score	0.033421 (rank : 1189)	θ value	1.81305 (rank : 201)
Query Neighborhood Hits	326	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

TEX15_HUMAN
NC score	0.033419 (rank : 1190)	θ value	6.88961 (rank : 303)
Query Neighborhood Hits	326	Target Neighborhood Hits	174	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

RHG12_HUMAN
NC score	0.032713 (rank : 1191)	θ value	1.38821 (rank : 187)
Query Neighborhood Hits	326	Target Neighborhood Hits	190	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CHD2_HUMAN
NC score	0.032482 (rank : 1192)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	326	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CCD25_MOUSE
NC score	0.032162 (rank : 1193)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	326	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q78PG9, Q9CSQ8, Q9CUF8	Gene names	Ccdc25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

SRR35_HUMAN
NC score	0.031634 (rank : 1194)	θ value	1.81305 (rank : 207)
Query Neighborhood Hits	326	Target Neighborhood Hits	215	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXF0, Q8WW25	Gene names	SRRP35
Domain Architecture
Description	35 kDa SR repressor protein (SRrp35).

ANGL3_MOUSE
NC score	0.031318 (rank : 1195)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	326	Target Neighborhood Hits	306	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

NO40_HUMAN
NC score	0.030388 (rank : 1196)	θ value	2.36792 (rank : 213)
Query Neighborhood Hits	326	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP64, Q6PKH4, Q9NYG4, Q9P0M8	Gene names	ZCCHC17, PS1D
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein) (Pnn-interacting nucleolar protein).

PRGC2_MOUSE
NC score	0.030351 (rank : 1197)	θ value	5.27518 (rank : 275)
Query Neighborhood Hits	326	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

DDX21_MOUSE
NC score	0.029870 (rank : 1198)	θ value	0.163984 (rank : 95)
Query Neighborhood Hits	326	Target Neighborhood Hits	350	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

JAD1A_HUMAN
NC score	0.029409 (rank : 1199)	θ value	5.27518 (rank : 269)
Query Neighborhood Hits	326	Target Neighborhood Hits	328	Shared Neighborhood Hits	50
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JHD2C_MOUSE
NC score	0.029326 (rank : 1200)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	326	Target Neighborhood Hits	297	Shared Neighborhood Hits	40
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

BRD2_HUMAN
NC score	0.028906 (rank : 1201)	θ value	3.0926 (rank : 224)
Query Neighborhood Hits	326	Target Neighborhood Hits	242	Shared Neighborhood Hits	25
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

EDC3_MOUSE
NC score	0.028808 (rank : 1202)	θ value	3.0926 (rank : 226)
Query Neighborhood Hits	326	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2D3, Q3THV7	Gene names	Edc3, Yjdc
Domain Architecture	No domain graphic available
Description	Enhancer of mRNA decapping protein 3 (YjeF domain-containing protein 1).

DACH2_HUMAN
NC score	0.027728 (rank : 1203)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	326	Target Neighborhood Hits	122	Shared Neighborhood Hits	24
SwissProt Accessions	Q96NX9, Q8NAY3, Q8ND17, Q96N55	Gene names	DACH2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

CCD25_HUMAN
NC score	0.027699 (rank : 1204)	θ value	8.99809 (rank : 309)
Query Neighborhood Hits	326	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q86WR0, Q96SI2, Q9NV98	Gene names	CCDC25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

DACH2_MOUSE
NC score	0.027499 (rank : 1205)	θ value	8.99809 (rank : 313)
Query Neighborhood Hits	326	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	Q925Q8, Q8BMA0	Gene names	Dach2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

DDX21_HUMAN
NC score	0.026601 (rank : 1206)	θ value	0.62314 (rank : 138)
Query Neighborhood Hits	326	Target Neighborhood Hits	308	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

PF21B_HUMAN
NC score	0.025623 (rank : 1207)	θ value	6.88961 (rank : 297)
Query Neighborhood Hits	326	Target Neighborhood Hits	197	Shared Neighborhood Hits	25
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

CLOCK_MOUSE
NC score	0.024368 (rank : 1208)	θ value	2.36792 (rank : 211)
Query Neighborhood Hits	326	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
NC score	0.023413 (rank : 1209)	θ value	3.0926 (rank : 225)
Query Neighborhood Hits	326	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

EDC3_HUMAN
NC score	0.023394 (rank : 1210)	θ value	8.99809 (rank : 316)
Query Neighborhood Hits	326	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96F86, Q9H797	Gene names	EDC3, YJDC
Domain Architecture	No domain graphic available
Description	Enhancer of mRNA decapping protein 3 (YjeF domain-containing protein 1).

CIZ1_HUMAN
NC score	0.022653 (rank : 1211)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	326	Target Neighborhood Hits	359	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

SNPC1_HUMAN
NC score	0.021267 (rank : 1212)	θ value	5.27518 (rank : 280)
Query Neighborhood Hits	326	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q16533	Gene names	SNAPC1, SNAP43
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (snRNA- activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) (Small nuclear RNA-activating complex polypeptide 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE- binding factor subunit gamma) (PTF subunit gamma).

PRP16_HUMAN
NC score	0.018715 (rank : 1213)	θ value	1.81305 (rank : 203)
Query Neighborhood Hits	326	Target Neighborhood Hits	135	Shared Neighborhood Hits	18
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

RL4_HUMAN
NC score	0.018486 (rank : 1214)	θ value	6.88961 (rank : 300)
Query Neighborhood Hits	326	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P36578, P39029, Q4VBR0, Q969Z9	Gene names	RPL4, RPL1
Domain Architecture
Description	60S ribosomal protein L4 (L1).

LRC59_MOUSE
NC score	0.017300 (rank : 1215)	θ value	2.36792 (rank : 212)
Query Neighborhood Hits	326	Target Neighborhood Hits	415	Shared Neighborhood Hits	26
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

EXOSX_MOUSE
NC score	0.016876 (rank : 1216)	θ value	5.27518 (rank : 267)
Query Neighborhood Hits	326	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P56960, Q9QYS8, Q9R0B1	Gene names	Exosc10, Pmscl2
Domain Architecture
Description	Exosome component 10 (Polymyositis/scleroderma autoantigen 2 homolog) (Autoantigen PM/Scl 2 homolog).

RCOR2_HUMAN
NC score	0.016660 (rank : 1217)	θ value	5.27518 (rank : 278)
Query Neighborhood Hits	326	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

ADA30_HUMAN
NC score	0.016523 (rank : 1218)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	326	Target Neighborhood Hits	391	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

EHMT2_MOUSE
NC score	0.015512 (rank : 1219)	θ value	5.27518 (rank : 266)
Query Neighborhood Hits	326	Target Neighborhood Hits	750	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

DDX27_HUMAN
NC score	0.013147 (rank : 1220)	θ value	8.99809 (rank : 315)
Query Neighborhood Hits	326	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

EHMT2_HUMAN
NC score	0.011568 (rank : 1221)	θ value	4.03905 (rank : 244)
Query Neighborhood Hits	326	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

BC11A_MOUSE
NC score	0.011551 (rank : 1222)	θ value	0.279714 (rank : 113)
Query Neighborhood Hits	326	Target Neighborhood Hits	732	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

ARMX5_MOUSE
NC score	0.011483 (rank : 1223)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	326	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

CAC1H_HUMAN
NC score	0.010584 (rank : 1224)	θ value	4.03905 (rank : 238)
Query Neighborhood Hits	326	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

PJA1_MOUSE
NC score	0.010056 (rank : 1225)	θ value	6.88961 (rank : 298)
Query Neighborhood Hits	326	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

BC11A_HUMAN
NC score	0.007728 (rank : 1226)	θ value	0.279714 (rank : 112)
Query Neighborhood Hits	326	Target Neighborhood Hits	745	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

SCN2A_HUMAN
NC score	0.005958 (rank : 1227)	θ value	6.88961 (rank : 302)
Query Neighborhood Hits	326	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

LOX12_MOUSE
NC score	0.004190 (rank : 1228)	θ value	8.99809 (rank : 320)
Query Neighborhood Hits	326	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

S12A4_MOUSE
NC score	0.003799 (rank : 1229)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	326	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIS8, O55069, Q9ET57	Gene names	Slc12a4, Kcc1
Domain Architecture
Description	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1).

ZFP37_MOUSE
NC score	0.000832 (rank : 1230)	θ value	0.365318 (rank : 125)
Query Neighborhood Hits	326	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).