Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : RUSC2_HUMAN

For an explanation of this page, click here

RUSC2_HUMAN
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RUSC2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	205	Target Neighborhood Hits	205	Shared Neighborhood Hits	205
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RUSC2_MOUSE
θ value	0 (rank : 2)	NC score	0.934883 (rank : 2)
Query Neighborhood Hits	205	Target Neighborhood Hits	305	Shared Neighborhood Hits	93
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RUSC1_HUMAN
θ value	3.0428e-56 (rank : 3)	NC score	0.711900 (rank : 3)
Query Neighborhood Hits	205	Target Neighborhood Hits	226	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

RUSC1_MOUSE
θ value	9.83387e-39 (rank : 4)	NC score	0.681593 (rank : 4)
Query Neighborhood Hits	205	Target Neighborhood Hits	206	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

EFS_MOUSE
θ value	0.000121331 (rank : 5)	NC score	0.239928 (rank : 5)
Query Neighborhood Hits	205	Target Neighborhood Hits	389	Shared Neighborhood Hits	75
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

RHG04_HUMAN
θ value	0.000461057 (rank : 6)	NC score	0.155842 (rank : 15)
Query Neighborhood Hits	205	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

GRAP_HUMAN
θ value	0.00175202 (rank : 7)	NC score	0.171430 (rank : 8)
Query Neighborhood Hits	205	Target Neighborhood Hits	307	Shared Neighborhood Hits	70
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

ITSN1_HUMAN
θ value	0.00228821 (rank : 8)	NC score	0.127057 (rank : 29)
Query Neighborhood Hits	205	Target Neighborhood Hits	1757	Shared Neighborhood Hits	95
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_HUMAN
θ value	0.00228821 (rank : 9)	NC score	0.130830 (rank : 26)
Query Neighborhood Hits	205	Target Neighborhood Hits	1173	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

GRAP_MOUSE
θ value	0.00509761 (rank : 10)	NC score	0.163109 (rank : 9)
Query Neighborhood Hits	205	Target Neighborhood Hits	309	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

MKL1_MOUSE
θ value	0.00509761 (rank : 11)	NC score	0.077800 (rank : 97)
Query Neighborhood Hits	205	Target Neighborhood Hits	667	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

EFS_HUMAN
θ value	0.00665767 (rank : 12)	NC score	0.224815 (rank : 6)
Query Neighborhood Hits	205	Target Neighborhood Hits	348	Shared Neighborhood Hits	73
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

ITSN2_MOUSE
θ value	0.00665767 (rank : 13)	NC score	0.122721 (rank : 35)
Query Neighborhood Hits	205	Target Neighborhood Hits	1371	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ADA2B_HUMAN
θ value	0.00869519 (rank : 14)	NC score	0.016794 (rank : 271)
Query Neighborhood Hits	205	Target Neighborhood Hits	881	Shared Neighborhood Hits	5
SwissProt Accessions	P18089, Q4TUH9, Q53RF2, Q9BZK0	Gene names	ADRA2B
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor) (Alpha-2 adrenergic receptor subtype C2).

ITSN1_MOUSE
θ value	0.0113563 (rank : 15)	NC score	0.126309 (rank : 30)
Query Neighborhood Hits	205	Target Neighborhood Hits	1669	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NCF2_HUMAN
θ value	0.0113563 (rank : 16)	NC score	0.213482 (rank : 7)
Query Neighborhood Hits	205	Target Neighborhood Hits	229	Shared Neighborhood Hits	63
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

MAGE1_HUMAN
θ value	0.0148317 (rank : 17)	NC score	0.049791 (rank : 193)
Query Neighborhood Hits	205	Target Neighborhood Hits	1389	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NFH_MOUSE
θ value	0.0148317 (rank : 18)	NC score	0.045259 (rank : 197)
Query Neighborhood Hits	205	Target Neighborhood Hits	2247	Shared Neighborhood Hits	89
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SH3G1_HUMAN
θ value	0.0148317 (rank : 19)	NC score	0.152881 (rank : 17)
Query Neighborhood Hits	205	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

NCOA6_MOUSE
θ value	0.0193708 (rank : 20)	NC score	0.079304 (rank : 94)
Query Neighborhood Hits	205	Target Neighborhood Hits	1076	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PPIP1_HUMAN
θ value	0.0193708 (rank : 21)	NC score	0.162460 (rank : 10)
Query Neighborhood Hits	205	Target Neighborhood Hits	389	Shared Neighborhood Hits	67
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

ADA2B_MOUSE
θ value	0.0563607 (rank : 22)	NC score	0.024645 (rank : 242)
Query Neighborhood Hits	205	Target Neighborhood Hits	891	Shared Neighborhood Hits	7
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).

GRAP2_MOUSE
θ value	0.0736092 (rank : 23)	NC score	0.161714 (rank : 11)
Query Neighborhood Hits	205	Target Neighborhood Hits	297	Shared Neighborhood Hits	68
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

SPTA1_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.090646 (rank : 75)
Query Neighborhood Hits	205	Target Neighborhood Hits	748	Shared Neighborhood Hits	68
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TARA_HUMAN
θ value	0.0736092 (rank : 25)	NC score	0.067259 (rank : 134)
Query Neighborhood Hits	205	Target Neighborhood Hits	1626	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GRAP2_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.159906 (rank : 12)
Query Neighborhood Hits	205	Target Neighborhood Hits	304	Shared Neighborhood Hits	70
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

MDC1_HUMAN
θ value	0.0961366 (rank : 27)	NC score	0.074532 (rank : 107)
Query Neighborhood Hits	205	Target Neighborhood Hits	1446	Shared Neighborhood Hits	70
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	0.0961366 (rank : 28)	NC score	0.074809 (rank : 105)
Query Neighborhood Hits	205	Target Neighborhood Hits	998	Shared Neighborhood Hits	59
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ALO17_HUMAN
θ value	0.125558 (rank : 29)	NC score	0.063780 (rank : 141)
Query Neighborhood Hits	205	Target Neighborhood Hits	317	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

GRB2_HUMAN
θ value	0.125558 (rank : 30)	NC score	0.159426 (rank : 13)
Query Neighborhood Hits	205	Target Neighborhood Hits	310	Shared Neighborhood Hits	69
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.159358 (rank : 14)
Query Neighborhood Hits	205	Target Neighborhood Hits	312	Shared Neighborhood Hits	69
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

SPTA2_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.083803 (rank : 85)
Query Neighborhood Hits	205	Target Neighborhood Hits	888	Shared Neighborhood Hits	71
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

TENN_MOUSE
θ value	0.125558 (rank : 33)	NC score	0.020783 (rank : 257)
Query Neighborhood Hits	205	Target Neighborhood Hits	484	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ANK2_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.026336 (rank : 234)
Query Neighborhood Hits	205	Target Neighborhood Hits	1615	Shared Neighborhood Hits	67
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BCAR1_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.155121 (rank : 16)
Query Neighborhood Hits	205	Target Neighborhood Hits	438	Shared Neighborhood Hits	78
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

JPH2_HUMAN
θ value	0.163984 (rank : 36)	NC score	0.041515 (rank : 203)
Query Neighborhood Hits	205	Target Neighborhood Hits	639	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

RGS3_MOUSE
θ value	0.163984 (rank : 37)	NC score	0.050835 (rank : 187)
Query Neighborhood Hits	205	Target Neighborhood Hits	1621	Shared Neighborhood Hits	78
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SELPL_MOUSE
θ value	0.163984 (rank : 38)	NC score	0.077792 (rank : 98)
Query Neighborhood Hits	205	Target Neighborhood Hits	588	Shared Neighborhood Hits	47
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

TXK_MOUSE
θ value	0.163984 (rank : 39)	NC score	0.036222 (rank : 212)
Query Neighborhood Hits	205	Target Neighborhood Hits	980	Shared Neighborhood Hits	62
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

CBP_MOUSE
θ value	0.279714 (rank : 40)	NC score	0.053169 (rank : 175)
Query Neighborhood Hits	205	Target Neighborhood Hits	1051	Shared Neighborhood Hits	65
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CTDP1_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.060057 (rank : 149)
Query Neighborhood Hits	205	Target Neighborhood Hits	416	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

NPHP1_MOUSE
θ value	0.279714 (rank : 42)	NC score	0.132979 (rank : 24)
Query Neighborhood Hits	205	Target Neighborhood Hits	267	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

SRMS_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.027915 (rank : 232)
Query Neighborhood Hits	205	Target Neighborhood Hits	946	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

STK10_HUMAN
θ value	0.279714 (rank : 44)	NC score	0.021766 (rank : 252)
Query Neighborhood Hits	205	Target Neighborhood Hits	1921	Shared Neighborhood Hits	47
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ABL1_HUMAN
θ value	0.365318 (rank : 45)	NC score	0.040187 (rank : 205)
Query Neighborhood Hits	205	Target Neighborhood Hits	1220	Shared Neighborhood Hits	74
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	0.365318 (rank : 46)	NC score	0.040687 (rank : 204)
Query Neighborhood Hits	205	Target Neighborhood Hits	1178	Shared Neighborhood Hits	73
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CK024_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.095084 (rank : 65)
Query Neighborhood Hits	205	Target Neighborhood Hits	408	Shared Neighborhood Hits	40
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

TCGAP_HUMAN
θ value	0.365318 (rank : 48)	NC score	0.080581 (rank : 91)
Query Neighborhood Hits	205	Target Neighborhood Hits	872	Shared Neighborhood Hits	86
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ABL2_HUMAN
θ value	0.47712 (rank : 49)	NC score	0.036032 (rank : 215)
Query Neighborhood Hits	205	Target Neighborhood Hits	1045	Shared Neighborhood Hits	53
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ACH10_HUMAN
θ value	0.47712 (rank : 50)	NC score	0.016105 (rank : 274)
Query Neighborhood Hits	205	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZZ6	Gene names	CHRNA10, NACHRA10
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-10 precursor (Nicotinic acetylcholine receptor subunit alpha 10) (NACHR alpha 10).

CAC1G_HUMAN
θ value	0.47712 (rank : 51)	NC score	0.037166 (rank : 209)
Query Neighborhood Hits	205	Target Neighborhood Hits	587	Shared Neighborhood Hits	34
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CIC_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.056217 (rank : 159)
Query Neighborhood Hits	205	Target Neighborhood Hits	992	Shared Neighborhood Hits	63
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

NCK1_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.141163 (rank : 20)
Query Neighborhood Hits	205	Target Neighborhood Hits	312	Shared Neighborhood Hits	69
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

ARNT_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.023370 (rank : 246)
Query Neighborhood Hits	205	Target Neighborhood Hits	213	Shared Neighborhood Hits	15
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BCAR1_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.147120 (rank : 18)
Query Neighborhood Hits	205	Target Neighborhood Hits	554	Shared Neighborhood Hits	82
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CAC1A_MOUSE
θ value	0.62314 (rank : 56)	NC score	0.025934 (rank : 238)
Query Neighborhood Hits	205	Target Neighborhood Hits	267	Shared Neighborhood Hits	21
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

DNMBP_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.124270 (rank : 33)
Query Neighborhood Hits	205	Target Neighborhood Hits	413	Shared Neighborhood Hits	67
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

LRC56_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.061473 (rank : 146)
Query Neighborhood Hits	205	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

OGFR_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.068004 (rank : 132)
Query Neighborhood Hits	205	Target Neighborhood Hits	1582	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RECQ5_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.041625 (rank : 201)
Query Neighborhood Hits	205	Target Neighborhood Hits	390	Shared Neighborhood Hits	31
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SRBS1_MOUSE
θ value	0.62314 (rank : 61)	NC score	0.133215 (rank : 22)
Query Neighborhood Hits	205	Target Neighborhood Hits	409	Shared Neighborhood Hits	76
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

AHI1_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.106211 (rank : 51)
Query Neighborhood Hits	205	Target Neighborhood Hits	496	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

BAZ2A_MOUSE
θ value	0.813845 (rank : 63)	NC score	0.036906 (rank : 211)
Query Neighborhood Hits	205	Target Neighborhood Hits	744	Shared Neighborhood Hits	51
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

GPTC8_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.053172 (rank : 174)
Query Neighborhood Hits	205	Target Neighborhood Hits	366	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

LNK_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.053556 (rank : 171)
Query Neighborhood Hits	205	Target Neighborhood Hits	151	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

PDZD2_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.050275 (rank : 190)
Query Neighborhood Hits	205	Target Neighborhood Hits	772	Shared Neighborhood Hits	51
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SPTA1_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.077730 (rank : 99)
Query Neighborhood Hits	205	Target Neighborhood Hits	675	Shared Neighborhood Hits	67
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CF150_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.050651 (rank : 188)
Query Neighborhood Hits	205	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

GPS2_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.094915 (rank : 66)
Query Neighborhood Hits	205	Target Neighborhood Hits	459	Shared Neighborhood Hits	18
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

MINK1_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.016595 (rank : 272)
Query Neighborhood Hits	205	Target Neighborhood Hits	1477	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

SRGP1_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.091674 (rank : 70)
Query Neighborhood Hits	205	Target Neighborhood Hits	390	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SSBP4_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.028355 (rank : 230)
Query Neighborhood Hits	205	Target Neighborhood Hits	753	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TBX21_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.019131 (rank : 262)
Query Neighborhood Hits	205	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

ZYX_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.030079 (rank : 227)
Query Neighborhood Hits	205	Target Neighborhood Hits	387	Shared Neighborhood Hits	35
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

B4GT1_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.023840 (rank : 243)
Query Neighborhood Hits	205	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CAC1A_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.025000 (rank : 239)
Query Neighborhood Hits	205	Target Neighborhood Hits	387	Shared Neighborhood Hits	25
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CSPG3_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.019076 (rank : 264)
Query Neighborhood Hits	205	Target Neighborhood Hits	657	Shared Neighborhood Hits	29
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DOS_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.049127 (rank : 194)
Query Neighborhood Hits	205	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

ERBB2_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.017382 (rank : 269)
Query Neighborhood Hits	205	Target Neighborhood Hits	1073	Shared Neighborhood Hits	25
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

FYN_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.044903 (rank : 199)
Query Neighborhood Hits	205	Target Neighborhood Hits	1078	Shared Neighborhood Hits	71
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.045422 (rank : 196)
Query Neighborhood Hits	205	Target Neighborhood Hits	1073	Shared Neighborhood Hits	71
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GCC1_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.028521 (rank : 229)
Query Neighborhood Hits	205	Target Neighborhood Hits	777	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

HNF1A_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.033102 (rank : 221)
Query Neighborhood Hits	205	Target Neighborhood Hits	193	Shared Neighborhood Hits	14
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

LRIG3_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.005082 (rank : 306)
Query Neighborhood Hits	205	Target Neighborhood Hits	611	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

MLL3_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.047190 (rank : 195)
Query Neighborhood Hits	205	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SFR15_HUMAN
θ value	1.38821 (rank : 86)	NC score	0.058216 (rank : 154)
Query Neighborhood Hits	205	Target Neighborhood Hits	368	Shared Neighborhood Hits	32
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SH3G1_MOUSE
θ value	1.38821 (rank : 87)	NC score	0.132367 (rank : 25)
Query Neighborhood Hits	205	Target Neighborhood Hits	291	Shared Neighborhood Hits	65
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G2_MOUSE
θ value	1.38821 (rank : 88)	NC score	0.130545 (rank : 27)
Query Neighborhood Hits	205	Target Neighborhood Hits	319	Shared Neighborhood Hits	67
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G3_MOUSE
θ value	1.38821 (rank : 89)	NC score	0.123172 (rank : 34)
Query Neighborhood Hits	205	Target Neighborhood Hits	236	Shared Neighborhood Hits	62
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SMG7_MOUSE
θ value	1.38821 (rank : 90)	NC score	0.050149 (rank : 191)
Query Neighborhood Hits	205	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

ZSCA5_HUMAN
θ value	1.38821 (rank : 91)	NC score	0.000236 (rank : 311)
Query Neighborhood Hits	205	Target Neighborhood Hits	862	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

DDEF2_MOUSE
θ value	1.81305 (rank : 92)	NC score	0.073674 (rank : 115)
Query Neighborhood Hits	205	Target Neighborhood Hits	625	Shared Neighborhood Hits	74
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

IQEC3_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.022411 (rank : 251)
Query Neighborhood Hits	205	Target Neighborhood Hits	274	Shared Neighborhood Hits	24
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

NCF4_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.146038 (rank : 19)
Query Neighborhood Hits	205	Target Neighborhood Hits	161	Shared Neighborhood Hits	55
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

PHLPP_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.022516 (rank : 250)
Query Neighborhood Hits	205	Target Neighborhood Hits	604	Shared Neighborhood Hits	33
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PK1L1_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.037331 (rank : 208)
Query Neighborhood Hits	205	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

SRGP2_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.097591 (rank : 61)
Query Neighborhood Hits	205	Target Neighborhood Hits	331	Shared Neighborhood Hits	58
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRRM2_MOUSE
θ value	1.81305 (rank : 98)	NC score	0.068587 (rank : 131)
Query Neighborhood Hits	205	Target Neighborhood Hits	1470	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCF19_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.045069 (rank : 198)
Query Neighborhood Hits	205	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

TS13_MOUSE
θ value	1.81305 (rank : 100)	NC score	0.036946 (rank : 210)
Query Neighborhood Hits	205	Target Neighborhood Hits	191	Shared Neighborhood Hits	7
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

USH1C_MOUSE
θ value	1.81305 (rank : 101)	NC score	0.036089 (rank : 214)
Query Neighborhood Hits	205	Target Neighborhood Hits	557	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

CD2AP_MOUSE
θ value	2.36792 (rank : 102)	NC score	0.124896 (rank : 32)
Query Neighborhood Hits	205	Target Neighborhood Hits	336	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

DLL1_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.006868 (rank : 303)
Query Neighborhood Hits	205	Target Neighborhood Hits	455	Shared Neighborhood Hits	8
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

FNBP2_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.085972 (rank : 81)
Query Neighborhood Hits	205	Target Neighborhood Hits	432	Shared Neighborhood Hits	60
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GRIN1_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.049885 (rank : 192)
Query Neighborhood Hits	205	Target Neighborhood Hits	337	Shared Neighborhood Hits	37
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MAST2_HUMAN
θ value	2.36792 (rank : 106)	NC score	0.008787 (rank : 297)
Query Neighborhood Hits	205	Target Neighborhood Hits	1189	Shared Neighborhood Hits	44
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NCOA2_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.021701 (rank : 253)
Query Neighborhood Hits	205	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

OSBP2_HUMAN
θ value	2.36792 (rank : 108)	NC score	0.014883 (rank : 279)
Query Neighborhood Hits	205	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

PERQ1_MOUSE
θ value	2.36792 (rank : 109)	NC score	0.035462 (rank : 217)
Query Neighborhood Hits	205	Target Neighborhood Hits	215	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

SRGP2_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.098952 (rank : 59)
Query Neighborhood Hits	205	Target Neighborhood Hits	324	Shared Neighborhood Hits	59
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

T22D4_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.036194 (rank : 213)
Query Neighborhood Hits	205	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

UBP28_MOUSE
θ value	2.36792 (rank : 112)	NC score	0.015476 (rank : 277)
Query Neighborhood Hits	205	Target Neighborhood Hits	178	Shared Neighborhood Hits	5
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

ANM2_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.084712 (rank : 84)
Query Neighborhood Hits	205	Target Neighborhood Hits	175	Shared Neighborhood Hits	54
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ARHG9_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.091735 (rank : 69)
Query Neighborhood Hits	205	Target Neighborhood Hits	235	Shared Neighborhood Hits	62
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.091344 (rank : 72)
Query Neighborhood Hits	205	Target Neighborhood Hits	234	Shared Neighborhood Hits	62
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

CASL_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.112992 (rank : 41)
Query Neighborhood Hits	205	Target Neighborhood Hits	225	Shared Neighborhood Hits	55
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

LCK_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.031352 (rank : 225)
Query Neighborhood Hits	205	Target Neighborhood Hits	981	Shared Neighborhood Hits	45
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

MPRI_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.025956 (rank : 237)
Query Neighborhood Hits	205	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

PCDA8_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.002792 (rank : 309)
Query Neighborhood Hits	205	Target Neighborhood Hits	187	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

PZRN3_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.012505 (rank : 285)
Query Neighborhood Hits	205	Target Neighborhood Hits	461	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SH3G3_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.120601 (rank : 36)
Query Neighborhood Hits	205	Target Neighborhood Hits	222	Shared Neighborhood Hits	61
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SMG5_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.024835 (rank : 241)
Query Neighborhood Hits	205	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

SYP2L_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.053362 (rank : 173)
Query Neighborhood Hits	205	Target Neighborhood Hits	400	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CU002_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.026613 (rank : 233)
Query Neighborhood Hits	205	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	O43822, O14993, Q99837, Q99838	Gene names	C21orf2
Domain Architecture	No domain graphic available
Description	Protein C21orf2 (C21orf-HUMF09G8.5) (YF5/A2).

E41L2_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.007042 (rank : 301)
Query Neighborhood Hits	205	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

EPN3_MOUSE
θ value	4.03905 (rank : 126)	NC score	0.023410 (rank : 245)
Query Neighborhood Hits	205	Target Neighborhood Hits	312	Shared Neighborhood Hits	29
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

HXD3_HUMAN
θ value	4.03905 (rank : 127)	NC score	0.010114 (rank : 290)
Query Neighborhood Hits	205	Target Neighborhood Hits	433	Shared Neighborhood Hits	17
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

MATK_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.030211 (rank : 226)
Query Neighborhood Hits	205	Target Neighborhood Hits	954	Shared Neighborhood Hits	42
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MICA2_HUMAN
θ value	4.03905 (rank : 129)	NC score	0.008732 (rank : 298)
Query Neighborhood Hits	205	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

MPRI_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.024900 (rank : 240)
Query Neighborhood Hits	205	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

MYCD_MOUSE
θ value	4.03905 (rank : 131)	NC score	0.033842 (rank : 218)
Query Neighborhood Hits	205	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

MYLK2_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.013447 (rank : 283)
Query Neighborhood Hits	205	Target Neighborhood Hits	920	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

NFKB2_MOUSE
θ value	4.03905 (rank : 133)	NC score	0.008728 (rank : 299)
Query Neighborhood Hits	205	Target Neighborhood Hits	326	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

RN166_MOUSE
θ value	4.03905 (rank : 134)	NC score	0.015455 (rank : 278)
Query Neighborhood Hits	205	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

SETBP_MOUSE
θ value	4.03905 (rank : 135)	NC score	0.042429 (rank : 200)
Query Neighborhood Hits	205	Target Neighborhood Hits	352	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SMAL1_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.013266 (rank : 284)
Query Neighborhood Hits	205	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SNPC2_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.025965 (rank : 236)
Query Neighborhood Hits	205	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

ZN516_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.004918 (rank : 307)
Query Neighborhood Hits	205	Target Neighborhood Hits	1197	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN750_MOUSE
θ value	4.03905 (rank : 139)	NC score	0.035991 (rank : 216)
Query Neighborhood Hits	205	Target Neighborhood Hits	346	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

AIRE_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.015770 (rank : 275)
Query Neighborhood Hits	205	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ANR38_MOUSE
θ value	5.27518 (rank : 141)	NC score	0.010931 (rank : 289)
Query Neighborhood Hits	205	Target Neighborhood Hits	512	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASPP1_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.074587 (rank : 106)
Query Neighborhood Hits	205	Target Neighborhood Hits	956	Shared Neighborhood Hits	83
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	5.27518 (rank : 143)	NC score	0.075379 (rank : 101)
Query Neighborhood Hits	205	Target Neighborhood Hits	1244	Shared Neighborhood Hits	100
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

B3A3_MOUSE
θ value	5.27518 (rank : 144)	NC score	0.009814 (rank : 292)
Query Neighborhood Hits	205	Target Neighborhood Hits	112	Shared Neighborhood Hits	10
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

BAT2_HUMAN
θ value	5.27518 (rank : 145)	NC score	0.069280 (rank : 127)
Query Neighborhood Hits	205	Target Neighborhood Hits	931	Shared Neighborhood Hits	68
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.062369 (rank : 144)
Query Neighborhood Hits	205	Target Neighborhood Hits	947	Shared Neighborhood Hits	71
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CK016_MOUSE
θ value	5.27518 (rank : 147)	NC score	0.020208 (rank : 259)
Query Neighborhood Hits	205	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJR6, Q80XE7	Gene names	D7h11orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf16 homolog.

FA21C_HUMAN
θ value	5.27518 (rank : 148)	NC score	0.022882 (rank : 249)
Query Neighborhood Hits	205	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

FMN1B_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.028110 (rank : 231)
Query Neighborhood Hits	205	Target Neighborhood Hits	447	Shared Neighborhood Hits	39
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

MPP5_HUMAN
θ value	5.27518 (rank : 150)	NC score	0.033495 (rank : 219)
Query Neighborhood Hits	205	Target Neighborhood Hits	231	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	5.27518 (rank : 151)	NC score	0.033299 (rank : 220)
Query Neighborhood Hits	205	Target Neighborhood Hits	226	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MYLK_MOUSE
θ value	5.27518 (rank : 152)	NC score	0.011844 (rank : 287)
Query Neighborhood Hits	205	Target Neighborhood Hits	1489	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NMD3B_HUMAN
θ value	5.27518 (rank : 153)	NC score	0.006956 (rank : 302)
Query Neighborhood Hits	205	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

RN166_HUMAN
θ value	5.27518 (rank : 154)	NC score	0.014408 (rank : 282)
Query Neighborhood Hits	205	Target Neighborhood Hits	240	Shared Neighborhood Hits	4
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RPGF6_HUMAN
θ value	5.27518 (rank : 155)	NC score	0.014757 (rank : 280)
Query Neighborhood Hits	205	Target Neighborhood Hits	266	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

S1769_HUMAN
θ value	5.27518 (rank : 156)	NC score	0.023484 (rank : 244)
Query Neighborhood Hits	205	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q99871, Q96HS8, Q9NP54	Gene names	UIP1
Domain Architecture	No domain graphic available
Description	26S proteasome-associated UCH37-interacting protein 1 (X-linked protein STS1769).

SON_MOUSE
θ value	5.27518 (rank : 157)	NC score	0.037715 (rank : 207)
Query Neighborhood Hits	205	Target Neighborhood Hits	957	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

STAM2_MOUSE
θ value	5.27518 (rank : 158)	NC score	0.110647 (rank : 44)
Query Neighborhood Hits	205	Target Neighborhood Hits	285	Shared Neighborhood Hits	65
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

TRIO_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.023010 (rank : 248)
Query Neighborhood Hits	205	Target Neighborhood Hits	1580	Shared Neighborhood Hits	63
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

ANM2_MOUSE
θ value	6.88961 (rank : 160)	NC score	0.081257 (rank : 88)
Query Neighborhood Hits	205	Target Neighborhood Hits	175	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ARHG7_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.096219 (rank : 64)
Query Neighborhood Hits	205	Target Neighborhood Hits	396	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

BACH1_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.004105 (rank : 308)
Query Neighborhood Hits	205	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

CCD22_HUMAN
θ value	6.88961 (rank : 163)	NC score	0.017337 (rank : 270)
Query Neighborhood Hits	205	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CRSP7_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.020550 (rank : 258)
Query Neighborhood Hits	205	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CSPG2_MOUSE
θ value	6.88961 (rank : 165)	NC score	0.010035 (rank : 291)
Query Neighborhood Hits	205	Target Neighborhood Hits	711	Shared Neighborhood Hits	20
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

HCLS1_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.133116 (rank : 23)
Query Neighborhood Hits	205	Target Neighborhood Hits	358	Shared Neighborhood Hits	77
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCN4_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.021616 (rank : 254)
Query Neighborhood Hits	205	Target Neighborhood Hits	303	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HNF1A_MOUSE
θ value	6.88961 (rank : 168)	NC score	0.026222 (rank : 235)
Query Neighborhood Hits	205	Target Neighborhood Hits	212	Shared Neighborhood Hits	15
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

K1683_HUMAN
θ value	6.88961 (rank : 169)	NC score	0.031837 (rank : 224)
Query Neighborhood Hits	205	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

LCK_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.032336 (rank : 223)
Query Neighborhood Hits	205	Target Neighborhood Hits	987	Shared Neighborhood Hits	46
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

NPTX2_MOUSE
θ value	6.88961 (rank : 171)	NC score	0.008973 (rank : 295)
Query Neighborhood Hits	205	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	O70340	Gene names	Nptx2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

OTU7A_MOUSE
θ value	6.88961 (rank : 172)	NC score	0.017446 (rank : 268)
Query Neighborhood Hits	205	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

PTTG1_MOUSE
θ value	6.88961 (rank : 173)	NC score	0.019223 (rank : 261)
Query Neighborhood Hits	205	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQJ7, O88887, Q9Z2E6	Gene names	Pttg1, Pttg
Domain Architecture
Description	Securin (Pituitary tumor-transforming protein 1).

RRBP1_MOUSE
θ value	6.88961 (rank : 174)	NC score	0.029725 (rank : 228)
Query Neighborhood Hits	205	Target Neighborhood Hits	1650	Shared Neighborhood Hits	52
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TTBK1_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.021542 (rank : 255)
Query Neighborhood Hits	205	Target Neighborhood Hits	1058	Shared Neighborhood Hits	47
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

TULP4_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.016462 (rank : 273)
Query Neighborhood Hits	205	Target Neighborhood Hits	426	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

VINEX_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.137194 (rank : 21)
Query Neighborhood Hits	205	Target Neighborhood Hits	286	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

AHI1_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.089607 (rank : 79)
Query Neighborhood Hits	205	Target Neighborhood Hits	537	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AMOL1_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.009240 (rank : 294)
Query Neighborhood Hits	205	Target Neighborhood Hits	435	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

BRD8_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.020789 (rank : 256)
Query Neighborhood Hits	205	Target Neighborhood Hits	422	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BSN_MOUSE
θ value	8.99809 (rank : 181)	NC score	0.052140 (rank : 181)
Query Neighborhood Hits	205	Target Neighborhood Hits	2057	Shared Neighborhood Hits	95
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAR10_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.017926 (rank : 267)
Query Neighborhood Hits	205	Target Neighborhood Hits	569	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CELR3_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.001961 (rank : 310)
Query Neighborhood Hits	205	Target Neighborhood Hits	680	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CF064_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.019089 (rank : 263)
Query Neighborhood Hits	205	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPB0, Q9H0D8	Gene names	C6orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf64.

DDEF2_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.066653 (rank : 136)
Query Neighborhood Hits	205	Target Neighborhood Hits	599	Shared Neighborhood Hits	79
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DOT1L_HUMAN
θ value	8.99809 (rank : 186)	NC score	0.038246 (rank : 206)
Query Neighborhood Hits	205	Target Neighborhood Hits	660	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

HXD3_MOUSE
θ value	8.99809 (rank : 187)	NC score	0.008946 (rank : 296)
Query Neighborhood Hits	205	Target Neighborhood Hits	435	Shared Neighborhood Hits	17
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

ITB7_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.006295 (rank : 304)
Query Neighborhood Hits	205	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

KLF17_MOUSE
θ value	8.99809 (rank : 189)	NC score	-0.001877 (rank : 312)
Query Neighborhood Hits	205	Target Neighborhood Hits	684	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CFA7, Q3UT30, Q6P233, Q9D351	Gene names	Klf17, Gzf, Zfp393, Znf393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393) (Germ cell-specific zinc finger protein).

LARP4_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.019978 (rank : 260)
Query Neighborhood Hits	205	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LIRB4_HUMAN
θ value	8.99809 (rank : 191)	NC score	0.005279 (rank : 305)
Query Neighborhood Hits	205	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

MOCOS_MOUSE
θ value	8.99809 (rank : 192)	NC score	0.011296 (rank : 288)
Query Neighborhood Hits	205	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q14CH1	Gene names	Mocos
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS).

NACAM_MOUSE
θ value	8.99809 (rank : 193)	NC score	0.054053 (rank : 169)
Query Neighborhood Hits	205	Target Neighborhood Hits	1866	Shared Neighborhood Hits	93
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NAR1_HUMAN
θ value	8.99809 (rank : 194)	NC score	0.009582 (rank : 293)
Query Neighborhood Hits	205	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P52961, Q96KT9	Gene names	ART1
Domain Architecture
Description	GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 precursor (EC 2.4.2.31) (Mono(ADP-ribosyl)transferase) (CD296 antigen).

NIPBL_HUMAN
θ value	8.99809 (rank : 195)	NC score	0.023255 (rank : 247)
Query Neighborhood Hits	205	Target Neighborhood Hits	1311	Shared Neighborhood Hits	48
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PCNT_MOUSE
θ value	8.99809 (rank : 196)	NC score	0.014477 (rank : 281)
Query Neighborhood Hits	205	Target Neighborhood Hits	1207	Shared Neighborhood Hits	33
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RASF5_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.008312 (rank : 300)
Query Neighborhood Hits	205	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

RASF7_MOUSE
θ value	8.99809 (rank : 198)	NC score	0.011874 (rank : 286)
Query Neighborhood Hits	205	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

SC24C_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.032981 (rank : 222)
Query Neighborhood Hits	205	Target Neighborhood Hits	662	Shared Neighborhood Hits	36
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

STAM1_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.099989 (rank : 57)
Query Neighborhood Hits	205	Target Neighborhood Hits	271	Shared Neighborhood Hits	65
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TBC20_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.018128 (rank : 266)
Query Neighborhood Hits	205	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q96BZ9, Q5JWQ7, Q96NE1, Q9BYM7, Q9H140	Gene names	TBC1D20, C20orf140
Domain Architecture
Description	TBC1 domain family member 20.

TBC20_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.018182 (rank : 265)
Query Neighborhood Hits	205	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9I4, Q3TYW9, Q99LW2	Gene names	Tbc1d20
Domain Architecture
Description	TBC1 domain family member 20.

WDR46_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.015580 (rank : 276)
Query Neighborhood Hits	205	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

ZAR1_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.041547 (rank : 202)
Query Neighborhood Hits	205	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZSCA4_HUMAN
θ value	8.99809 (rank : 205)	NC score	-0.002268 (rank : 313)
Query Neighborhood Hits	205	Target Neighborhood Hits	713	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NAM6	Gene names	ZSCAN4, ZNF494
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494).

3BP1_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.051545 (rank : 183)
Query Neighborhood Hits	205	Target Neighborhood Hits	376	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ABI1_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.091567 (rank : 71)
Query Neighborhood Hits	205	Target Neighborhood Hits	257	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.093348 (rank : 67)
Query Neighborhood Hits	205	Target Neighborhood Hits	246	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.118580 (rank : 37)
Query Neighborhood Hits	205	Target Neighborhood Hits	350	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.112357 (rank : 42)
Query Neighborhood Hits	205	Target Neighborhood Hits	266	Shared Neighborhood Hits	67
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.073615 (rank : 116)
Query Neighborhood Hits	205	Target Neighborhood Hits	227	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.075197 (rank : 103)
Query Neighborhood Hits	205	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ARHG4_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.073769 (rank : 113)
Query Neighborhood Hits	205	Target Neighborhood Hits	242	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.060126 (rank : 148)
Query Neighborhood Hits	205	Target Neighborhood Hits	185	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG6_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.073427 (rank : 118)
Query Neighborhood Hits	205	Target Neighborhood Hits	376	Shared Neighborhood Hits	58
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.075316 (rank : 102)
Query Neighborhood Hits	205	Target Neighborhood Hits	394	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG7_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.085280 (rank : 83)
Query Neighborhood Hits	205	Target Neighborhood Hits	347	Shared Neighborhood Hits	61
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ATN1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.061048 (rank : 147)
Query Neighborhood Hits	205	Target Neighborhood Hits	676	Shared Neighborhood Hits	57
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BASP_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.053150 (rank : 176)
Query Neighborhood Hits	205	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BSN_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.053082 (rank : 177)
Query Neighborhood Hits	205	Target Neighborhood Hits	1537	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CASL_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.108599 (rank : 49)
Query Neighborhood Hits	205	Target Neighborhood Hits	259	Shared Neighborhood Hits	58
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CD2AP_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.110143 (rank : 45)
Query Neighborhood Hits	205	Target Neighborhood Hits	315	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CN155_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.053882 (rank : 170)
Query Neighborhood Hits	205	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CO039_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.050371 (rank : 189)
Query Neighborhood Hits	205	Target Neighborhood Hits	264	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CRKL_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.109939 (rank : 47)
Query Neighborhood Hits	205	Target Neighborhood Hits	313	Shared Neighborhood Hits	65
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.102233 (rank : 56)
Query Neighborhood Hits	205	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.103647 (rank : 55)
Query Neighborhood Hits	205	Target Neighborhood Hits	308	Shared Neighborhood Hits	66
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.104574 (rank : 53)
Query Neighborhood Hits	205	Target Neighborhood Hits	314	Shared Neighborhood Hits	66
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CT032_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.110128 (rank : 46)
Query Neighborhood Hits	205	Target Neighborhood Hits	235	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DBNL_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.081017 (rank : 89)
Query Neighborhood Hits	205	Target Neighborhood Hits	244	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.078766 (rank : 95)
Query Neighborhood Hits	205	Target Neighborhood Hits	306	Shared Neighborhood Hits	57
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DDEF1_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.052742 (rank : 179)
Query Neighborhood Hits	205	Target Neighborhood Hits	592	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DNMBP_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.103692 (rank : 54)
Query Neighborhood Hits	205	Target Neighborhood Hits	435	Shared Neighborhood Hits	72
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

EP300_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.053079 (rank : 178)
Query Neighborhood Hits	205	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ES8L3_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.056165 (rank : 160)
Query Neighborhood Hits	205	Target Neighborhood Hits	168	Shared Neighborhood Hits	56
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

GGN_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.055533 (rank : 163)
Query Neighborhood Hits	205	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GSCR1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.063161 (rank : 143)
Query Neighborhood Hits	205	Target Neighborhood Hits	674	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HCLS1_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.111299 (rank : 43)
Query Neighborhood Hits	205	Target Neighborhood Hits	329	Shared Neighborhood Hits	72
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

IASPP_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.090259 (rank : 76)
Query Neighborhood Hits	205	Target Neighborhood Hits	688	Shared Neighborhood Hits	91
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IASPP_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.080867 (rank : 90)
Query Neighborhood Hits	205	Target Neighborhood Hits	1024	Shared Neighborhood Hits	92
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LASP1_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.090790 (rank : 74)
Query Neighborhood Hits	205	Target Neighborhood Hits	293	Shared Neighborhood Hits	51
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.078436 (rank : 96)
Query Neighborhood Hits	205	Target Neighborhood Hits	297	Shared Neighborhood Hits	52
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MARCS_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.055280 (rank : 165)
Query Neighborhood Hits	205	Target Neighborhood Hits	227	Shared Neighborhood Hits	27
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MUC7_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.072380 (rank : 120)
Query Neighborhood Hits	205	Target Neighborhood Hits	538	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCF1_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.089625 (rank : 78)
Query Neighborhood Hits	205	Target Neighborhood Hits	198	Shared Neighborhood Hits	55
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.089752 (rank : 77)
Query Neighborhood Hits	205	Target Neighborhood Hits	198	Shared Neighborhood Hits	55
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCF4_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.127399 (rank : 28)
Query Neighborhood Hits	205	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK2_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.113974 (rank : 40)
Query Neighborhood Hits	205	Target Neighborhood Hits	310	Shared Neighborhood Hits	66
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCOA6_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.056881 (rank : 157)
Query Neighborhood Hits	205	Target Neighborhood Hits	1202	Shared Neighborhood Hits	69
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NEBL_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.069264 (rank : 128)
Query Neighborhood Hits	205	Target Neighborhood Hits	457	Shared Neighborhood Hits	53
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.064745 (rank : 138)
Query Neighborhood Hits	205	Target Neighborhood Hits	420	Shared Neighborhood Hits	60
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NOXO1_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.051628 (rank : 182)
Query Neighborhood Hits	205	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.064367 (rank : 140)
Query Neighborhood Hits	205	Target Neighborhood Hits	114	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHP1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.098987 (rank : 58)
Query Neighborhood Hits	205	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

OSTF1_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.090926 (rank : 73)
Query Neighborhood Hits	205	Target Neighborhood Hits	466	Shared Neighborhood Hits	65
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.086247 (rank : 80)
Query Neighborhood Hits	205	Target Neighborhood Hits	467	Shared Neighborhood Hits	65
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

PACN1_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.074392 (rank : 109)
Query Neighborhood Hits	205	Target Neighborhood Hits	320	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.074880 (rank : 104)
Query Neighborhood Hits	205	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN2_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.074495 (rank : 108)
Query Neighborhood Hits	205	Target Neighborhood Hits	339	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.073764 (rank : 114)
Query Neighborhood Hits	205	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.070415 (rank : 122)
Query Neighborhood Hits	205	Target Neighborhood Hits	385	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.074354 (rank : 110)
Query Neighborhood Hits	205	Target Neighborhood Hits	380	Shared Neighborhood Hits	59
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PCQAP_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.062192 (rank : 145)
Query Neighborhood Hits	205	Target Neighborhood Hits	549	Shared Neighborhood Hits	51
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PEX13_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.069254 (rank : 129)
Query Neighborhood Hits	205	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.069078 (rank : 130)
Query Neighborhood Hits	205	Target Neighborhood Hits	126	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PLCG1_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.054473 (rank : 168)
Query Neighborhood Hits	205	Target Neighborhood Hits	293	Shared Neighborhood Hits	56
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.059157 (rank : 151)
Query Neighborhood Hits	205	Target Neighborhood Hits	314	Shared Neighborhood Hits	57
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.059687 (rank : 150)
Query Neighborhood Hits	205	Target Neighborhood Hits	280	Shared Neighborhood Hits	58
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PPIP1_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.117620 (rank : 38)
Query Neighborhood Hits	205	Target Neighborhood Hits	377	Shared Neighborhood Hits	68
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PRB3_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.073506 (rank : 117)
Query Neighborhood Hits	205	Target Neighborhood Hits	318	Shared Neighborhood Hits	35
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.051083 (rank : 185)
Query Neighborhood Hits	205	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.056932 (rank : 156)
Query Neighborhood Hits	205	Target Neighborhood Hits	764	Shared Neighborhood Hits	56
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.051351 (rank : 184)
Query Neighborhood Hits	205	Target Neighborhood Hits	624	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.059002 (rank : 152)
Query Neighborhood Hits	205	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.053405 (rank : 172)
Query Neighborhood Hits	205	Target Neighborhood Hits	347	Shared Neighborhood Hits	37
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.050842 (rank : 186)
Query Neighborhood Hits	205	Target Neighborhood Hits	460	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RERE_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.052432 (rank : 180)
Query Neighborhood Hits	205	Target Neighborhood Hits	785	Shared Neighborhood Hits	55
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SH3G2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.114036 (rank : 39)
Query Neighborhood Hits	205	Target Neighborhood Hits	324	Shared Neighborhood Hits	64
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3K1_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.105872 (rank : 52)
Query Neighborhood Hits	205	Target Neighborhood Hits	341	Shared Neighborhood Hits	73
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.106725 (rank : 50)
Query Neighborhood Hits	205	Target Neighborhood Hits	332	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SHLB1_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.067887 (rank : 133)
Query Neighborhood Hits	205	Target Neighborhood Hits	96	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SHLB1_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.066758 (rank : 135)
Query Neighborhood Hits	205	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SHLB2_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.074257 (rank : 111)
Query Neighborhood Hits	205	Target Neighborhood Hits	86	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.075560 (rank : 100)
Query Neighborhood Hits	205	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SLAP2_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.058738 (rank : 153)
Query Neighborhood Hits	205	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.057507 (rank : 155)
Query Neighborhood Hits	205	Target Neighborhood Hits	136	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SNX18_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.054474 (rank : 167)
Query Neighborhood Hits	205	Target Neighborhood Hits	207	Shared Neighborhood Hits	45
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.055651 (rank : 162)
Query Neighborhood Hits	205	Target Neighborhood Hits	198	Shared Neighborhood Hits	45
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SRBS1_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.108722 (rank : 48)
Query Neighborhood Hits	205	Target Neighborhood Hits	396	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.098642 (rank : 60)
Query Neighborhood Hits	205	Target Neighborhood Hits	269	Shared Neighborhood Hits	65
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.096440 (rank : 63)
Query Neighborhood Hits	205	Target Neighborhood Hits	292	Shared Neighborhood Hits	64
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRRM1_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.065978 (rank : 137)
Query Neighborhood Hits	205	Target Neighborhood Hits	690	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.079483 (rank : 93)
Query Neighborhood Hits	205	Target Neighborhood Hits	966	Shared Neighborhood Hits	63
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.056633 (rank : 158)
Query Neighborhood Hits	205	Target Neighborhood Hits	1296	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

STAC3_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.073292 (rank : 119)
Query Neighborhood Hits	205	Target Neighborhood Hits	228	Shared Neighborhood Hits	55
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.073962 (rank : 112)
Query Neighborhood Hits	205	Target Neighborhood Hits	232	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.083533 (rank : 86)
Query Neighborhood Hits	205	Target Neighborhood Hits	276	Shared Neighborhood Hits	60
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.082315 (rank : 87)
Query Neighborhood Hits	205	Target Neighborhood Hits	268	Shared Neighborhood Hits	60
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAM1_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.096837 (rank : 62)
Query Neighborhood Hits	205	Target Neighborhood Hits	273	Shared Neighborhood Hits	63
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.092546 (rank : 68)
Query Neighborhood Hits	205	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

SYN1_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.054607 (rank : 166)
Query Neighborhood Hits	205	Target Neighborhood Hits	419	Shared Neighborhood Hits	57
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.055890 (rank : 161)
Query Neighborhood Hits	205	Target Neighborhood Hits	363	Shared Neighborhood Hits	52
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TAF4_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.085857 (rank : 82)
Query Neighborhood Hits	205	Target Neighborhood Hits	687	Shared Neighborhood Hits	60
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TCGAP_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.080428 (rank : 92)
Query Neighborhood Hits	205	Target Neighborhood Hits	409	Shared Neighborhood Hits	64
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

VAV2_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.070179 (rank : 123)
Query Neighborhood Hits	205	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.069809 (rank : 126)
Query Neighborhood Hits	205	Target Neighborhood Hits	456	Shared Neighborhood Hits	60
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.064615 (rank : 139)
Query Neighborhood Hits	205	Target Neighborhood Hits	398	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.063664 (rank : 142)
Query Neighborhood Hits	205	Target Neighborhood Hits	404	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.071704 (rank : 121)
Query Neighborhood Hits	205	Target Neighborhood Hits	452	Shared Neighborhood Hits	64
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.070080 (rank : 124)
Query Neighborhood Hits	205	Target Neighborhood Hits	430	Shared Neighborhood Hits	64
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VINEX_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.125937 (rank : 31)
Query Neighborhood Hits	205	Target Neighborhood Hits	270	Shared Neighborhood Hits	67
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

WASIP_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.055498 (rank : 164)
Query Neighborhood Hits	205	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.069892 (rank : 125)
Query Neighborhood Hits	205	Target Neighborhood Hits	392	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

Hits sorted by NC score

RUSC2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	205	Target Neighborhood Hits	205	Shared Neighborhood Hits	205
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RUSC2_MOUSE
NC score	0.934883 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	205	Target Neighborhood Hits	305	Shared Neighborhood Hits	93
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RUSC1_HUMAN
NC score	0.711900 (rank : 3)	θ value	3.0428e-56 (rank : 3)
Query Neighborhood Hits	205	Target Neighborhood Hits	226	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

RUSC1_MOUSE
NC score	0.681593 (rank : 4)	θ value	9.83387e-39 (rank : 4)
Query Neighborhood Hits	205	Target Neighborhood Hits	206	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

EFS_MOUSE
NC score	0.239928 (rank : 5)	θ value	0.000121331 (rank : 5)
Query Neighborhood Hits	205	Target Neighborhood Hits	389	Shared Neighborhood Hits	75
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

EFS_HUMAN
NC score	0.224815 (rank : 6)	θ value	0.00665767 (rank : 12)
Query Neighborhood Hits	205	Target Neighborhood Hits	348	Shared Neighborhood Hits	73
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

NCF2_HUMAN
NC score	0.213482 (rank : 7)	θ value	0.0113563 (rank : 16)
Query Neighborhood Hits	205	Target Neighborhood Hits	229	Shared Neighborhood Hits	63
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

GRAP_HUMAN
NC score	0.171430 (rank : 8)	θ value	0.00175202 (rank : 7)
Query Neighborhood Hits	205	Target Neighborhood Hits	307	Shared Neighborhood Hits	70
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
NC score	0.163109 (rank : 9)	θ value	0.00509761 (rank : 10)
Query Neighborhood Hits	205	Target Neighborhood Hits	309	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

PPIP1_HUMAN
NC score	0.162460 (rank : 10)	θ value	0.0193708 (rank : 21)
Query Neighborhood Hits	205	Target Neighborhood Hits	389	Shared Neighborhood Hits	67
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

GRAP2_MOUSE
NC score	0.161714 (rank : 11)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	205	Target Neighborhood Hits	297	Shared Neighborhood Hits	68
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP2_HUMAN
NC score	0.159906 (rank : 12)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	205	Target Neighborhood Hits	304	Shared Neighborhood Hits	70
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRB2_HUMAN
NC score	0.159426 (rank : 13)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	205	Target Neighborhood Hits	310	Shared Neighborhood Hits	69
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.159358 (rank : 14)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	205	Target Neighborhood Hits	312	Shared Neighborhood Hits	69
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

RHG04_HUMAN
NC score	0.155842 (rank : 15)	θ value	0.000461057 (rank : 6)
Query Neighborhood Hits	205	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

BCAR1_MOUSE
NC score	0.155121 (rank : 16)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	205	Target Neighborhood Hits	438	Shared Neighborhood Hits	78
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SH3G1_HUMAN
NC score	0.152881 (rank : 17)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	205	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

BCAR1_HUMAN
NC score	0.147120 (rank : 18)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	205	Target Neighborhood Hits	554	Shared Neighborhood Hits	82
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

NCF4_HUMAN
NC score	0.146038 (rank : 19)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	205	Target Neighborhood Hits	161	Shared Neighborhood Hits	55
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK1_HUMAN
NC score	0.141163 (rank : 20)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	205	Target Neighborhood Hits	312	Shared Neighborhood Hits	69
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

VINEX_MOUSE
NC score	0.137194 (rank : 21)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	205	Target Neighborhood Hits	286	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SRBS1_MOUSE
NC score	0.133215 (rank : 22)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	205	Target Neighborhood Hits	409	Shared Neighborhood Hits	76
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

HCLS1_HUMAN
NC score	0.133116 (rank : 23)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	205	Target Neighborhood Hits	358	Shared Neighborhood Hits	77
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

NPHP1_MOUSE
NC score	0.132979 (rank : 24)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	205	Target Neighborhood Hits	267	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

SH3G1_MOUSE
NC score	0.132367 (rank : 25)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	205	Target Neighborhood Hits	291	Shared Neighborhood Hits	65
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

ITSN2_HUMAN
NC score	0.130830 (rank : 26)	θ value	0.00228821 (rank : 9)
Query Neighborhood Hits	205	Target Neighborhood Hits	1173	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SH3G2_MOUSE
NC score	0.130545 (rank : 27)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	205	Target Neighborhood Hits	319	Shared Neighborhood Hits	67
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

NCF4_MOUSE
NC score	0.127399 (rank : 28)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	205	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

ITSN1_HUMAN
NC score	0.127057 (rank : 29)	θ value	0.00228821 (rank : 8)
Query Neighborhood Hits	205	Target Neighborhood Hits	1757	Shared Neighborhood Hits	95
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
NC score	0.126309 (rank : 30)	θ value	0.0113563 (rank : 15)
Query Neighborhood Hits	205	Target Neighborhood Hits	1669	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

VINEX_HUMAN
NC score	0.125937 (rank : 31)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	205	Target Neighborhood Hits	270	Shared Neighborhood Hits	67
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

CD2AP_MOUSE
NC score	0.124896 (rank : 32)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	205	Target Neighborhood Hits	336	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

DNMBP_HUMAN
NC score	0.124270 (rank : 33)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	205	Target Neighborhood Hits	413	Shared Neighborhood Hits	67
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SH3G3_MOUSE
NC score	0.123172 (rank : 34)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	205	Target Neighborhood Hits	236	Shared Neighborhood Hits	62
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

ITSN2_MOUSE
NC score	0.122721 (rank : 35)	θ value	0.00665767 (rank : 13)
Query Neighborhood Hits	205	Target Neighborhood Hits	1371	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

SH3G3_HUMAN
NC score	0.120601 (rank : 36)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	205	Target Neighborhood Hits	222	Shared Neighborhood Hits	61
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

ABI2_HUMAN
NC score	0.118580 (rank : 37)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	205	Target Neighborhood Hits	350	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

PPIP1_MOUSE
NC score	0.117620 (rank : 38)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	205	Target Neighborhood Hits	377	Shared Neighborhood Hits	68
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SH3G2_HUMAN
NC score	0.114036 (rank : 39)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	205	Target Neighborhood Hits	324	Shared Neighborhood Hits	64
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

NCK2_HUMAN
NC score	0.113974 (rank : 40)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	205	Target Neighborhood Hits	310	Shared Neighborhood Hits	66
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

CASL_MOUSE
NC score	0.112992 (rank : 41)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	205	Target Neighborhood Hits	225	Shared Neighborhood Hits	55
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

ABI2_MOUSE
NC score	0.112357 (rank : 42)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	205	Target Neighborhood Hits	266	Shared Neighborhood Hits	67
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

HCLS1_MOUSE
NC score	0.111299 (rank : 43)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	205	Target Neighborhood Hits	329	Shared Neighborhood Hits	72
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

STAM2_MOUSE
NC score	0.110647 (rank : 44)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	205	Target Neighborhood Hits	285	Shared Neighborhood Hits	65
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

CD2AP_HUMAN
NC score	0.110143 (rank : 45)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	205	Target Neighborhood Hits	315	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CT032_HUMAN
NC score	0.110128 (rank : 46)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	205	Target Neighborhood Hits	235	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CRKL_HUMAN
NC score	0.109939 (rank : 47)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	205	Target Neighborhood Hits	313	Shared Neighborhood Hits	65
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

SRBS1_HUMAN
NC score	0.108722 (rank : 48)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	205	Target Neighborhood Hits	396	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CASL_HUMAN
NC score	0.108599 (rank : 49)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	205	Target Neighborhood Hits	259	Shared Neighborhood Hits	58
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

SH3K1_MOUSE
NC score	0.106725 (rank : 50)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	205	Target Neighborhood Hits	332	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

AHI1_MOUSE
NC score	0.106211 (rank : 51)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	205	Target Neighborhood Hits	496	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

SH3K1_HUMAN
NC score	0.105872 (rank : 52)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	205	Target Neighborhood Hits	341	Shared Neighborhood Hits	73
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

CRK_MOUSE
NC score	0.104574 (rank : 53)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	205	Target Neighborhood Hits	314	Shared Neighborhood Hits	66
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

DNMBP_MOUSE
NC score	0.103692 (rank : 54)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	205	Target Neighborhood Hits	435	Shared Neighborhood Hits	72
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

CRK_HUMAN
NC score	0.103647 (rank : 55)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	205	Target Neighborhood Hits	308	Shared Neighborhood Hits	66
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRKL_MOUSE
NC score	0.102233 (rank : 56)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	205	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

STAM1_HUMAN
NC score	0.099989 (rank : 57)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	205	Target Neighborhood Hits	271	Shared Neighborhood Hits	65
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

NPHP1_HUMAN
NC score	0.098987 (rank : 58)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	205	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

SRGP2_MOUSE
NC score	0.098952 (rank : 59)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	205	Target Neighborhood Hits	324	Shared Neighborhood Hits	59
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRC8_HUMAN
NC score	0.098642 (rank : 60)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	205	Target Neighborhood Hits	269	Shared Neighborhood Hits	65
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRGP2_HUMAN
NC score	0.097591 (rank : 61)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	205	Target Neighborhood Hits	331	Shared Neighborhood Hits	58
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

STAM1_MOUSE
NC score	0.096837 (rank : 62)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	205	Target Neighborhood Hits	273	Shared Neighborhood Hits	63
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

SRC8_MOUSE
NC score	0.096440 (rank : 63)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	205	Target Neighborhood Hits	292	Shared Neighborhood Hits	64
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

ARHG7_MOUSE
NC score	0.096219 (rank : 64)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	205	Target Neighborhood Hits	396	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

CK024_HUMAN
NC score	0.095084 (rank : 65)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	205	Target Neighborhood Hits	408	Shared Neighborhood Hits	40
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

GPS2_HUMAN
NC score	0.094915 (rank : 66)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	205	Target Neighborhood Hits	459	Shared Neighborhood Hits	18
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

ABI1_MOUSE
NC score	0.093348 (rank : 67)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	205	Target Neighborhood Hits	246	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

STAM2_HUMAN
NC score	0.092546 (rank : 68)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	205	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

ARHG9_HUMAN
NC score	0.091735 (rank : 69)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	205	Target Neighborhood Hits	235	Shared Neighborhood Hits	62
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

SRGP1_HUMAN
NC score	0.091674 (rank : 70)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	205	Target Neighborhood Hits	390	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

ABI1_HUMAN
NC score	0.091567 (rank : 71)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	205	Target Neighborhood Hits	257	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ARHG9_MOUSE
NC score	0.091344 (rank : 72)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	205	Target Neighborhood Hits	234	Shared Neighborhood Hits	62
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

OSTF1_HUMAN
NC score	0.090926 (rank : 73)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	205	Target Neighborhood Hits	466	Shared Neighborhood Hits	65
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

LASP1_HUMAN
NC score	0.090790 (rank : 74)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	205	Target Neighborhood Hits	293	Shared Neighborhood Hits	51
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

SPTA1_HUMAN
NC score	0.090646 (rank : 75)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	205	Target Neighborhood Hits	748	Shared Neighborhood Hits	68
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

IASPP_HUMAN
NC score	0.090259 (rank : 76)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	205	Target Neighborhood Hits	688	Shared Neighborhood Hits	91
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NCF1_MOUSE
NC score	0.089752 (rank : 77)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	205	Target Neighborhood Hits	198	Shared Neighborhood Hits	55
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCF1_HUMAN
NC score	0.089625 (rank : 78)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	205	Target Neighborhood Hits	198	Shared Neighborhood Hits	55
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

AHI1_HUMAN
NC score	0.089607 (rank : 79)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	205	Target Neighborhood Hits	537	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

OSTF1_MOUSE
NC score	0.086247 (rank : 80)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	205	Target Neighborhood Hits	467	Shared Neighborhood Hits	65
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

FNBP2_HUMAN
NC score	0.085972 (rank : 81)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	205	Target Neighborhood Hits	432	Shared Neighborhood Hits	60
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

TAF4_HUMAN
NC score	0.085857 (rank : 82)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	205	Target Neighborhood Hits	687	Shared Neighborhood Hits	60
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ARHG7_HUMAN
NC score	0.085280 (rank : 83)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	205	Target Neighborhood Hits	347	Shared Neighborhood Hits	61
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ANM2_HUMAN
NC score	0.084712 (rank : 84)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	205	Target Neighborhood Hits	175	Shared Neighborhood Hits	54
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

SPTA2_HUMAN
NC score	0.083803 (rank : 85)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	205	Target Neighborhood Hits	888	Shared Neighborhood Hits	71
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

STAC_HUMAN
NC score	0.083533 (rank : 86)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	205	Target Neighborhood Hits	276	Shared Neighborhood Hits	60
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
NC score	0.082315 (rank : 87)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	205	Target Neighborhood Hits	268	Shared Neighborhood Hits	60
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ANM2_MOUSE
NC score	0.081257 (rank : 88)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	205	Target Neighborhood Hits	175	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

DBNL_HUMAN
NC score	0.081017 (rank : 89)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	205	Target Neighborhood Hits	244	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

IASPP_MOUSE
NC score	0.080867 (rank : 90)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	205	Target Neighborhood Hits	1024	Shared Neighborhood Hits	92
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TCGAP_HUMAN
NC score	0.080581 (rank : 91)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	205	Target Neighborhood Hits	872	Shared Neighborhood Hits	86
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
NC score	0.080428 (rank : 92)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	205	Target Neighborhood Hits	409	Shared Neighborhood Hits	64
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SRRM1_MOUSE
NC score	0.079483 (rank : 93)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	205	Target Neighborhood Hits	966	Shared Neighborhood Hits	63
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

NCOA6_MOUSE
NC score	0.079304 (rank : 94)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	205	Target Neighborhood Hits	1076	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

DBNL_MOUSE
NC score	0.078766 (rank : 95)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	205	Target Neighborhood Hits	306	Shared Neighborhood Hits	57
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

LASP1_MOUSE
NC score	0.078436 (rank : 96)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	205	Target Neighborhood Hits	297	Shared Neighborhood Hits	52
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MKL1_MOUSE
NC score	0.077800 (rank : 97)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	205	Target Neighborhood Hits	667	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SELPL_MOUSE
NC score	0.077792 (rank : 98)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	205	Target Neighborhood Hits	588	Shared Neighborhood Hits	47
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SPTA1_MOUSE
NC score	0.077730 (rank : 99)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	205	Target Neighborhood Hits	675	Shared Neighborhood Hits	67
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SHLB2_MOUSE
NC score	0.075560 (rank : 100)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	205	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

ASPP1_MOUSE
NC score	0.075379 (rank : 101)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	205	Target Neighborhood Hits	1244	Shared Neighborhood Hits	100
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ARHG6_MOUSE
NC score	0.075316 (rank : 102)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	205	Target Neighborhood Hits	394	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ABI3_MOUSE
NC score	0.075197 (rank : 103)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	205	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

PACN1_MOUSE
NC score	0.074880 (rank : 104)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	205	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

MDC1_MOUSE
NC score	0.074809 (rank : 105)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	205	Target Neighborhood Hits	998	Shared Neighborhood Hits	59
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ASPP1_HUMAN
NC score	0.074587 (rank : 106)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	205	Target Neighborhood Hits	956	Shared Neighborhood Hits	83
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MDC1_HUMAN
NC score	0.074532 (rank : 107)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	205	Target Neighborhood Hits	1446	Shared Neighborhood Hits	70
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PACN2_HUMAN
NC score	0.074495 (rank : 108)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	205	Target Neighborhood Hits	339	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN1_HUMAN
NC score	0.074392 (rank : 109)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	205	Target Neighborhood Hits	320	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN3_MOUSE
NC score	0.074354 (rank : 110)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	205	Target Neighborhood Hits	380	Shared Neighborhood Hits	59
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

SHLB2_HUMAN
NC score	0.074257 (rank : 111)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	205	Target Neighborhood Hits	86	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

STAC3_MOUSE
NC score	0.073962 (rank : 112)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	205	Target Neighborhood Hits	232	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

ARHG4_HUMAN
NC score	0.073769 (rank : 113)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	205	Target Neighborhood Hits	242	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

PACN2_MOUSE
NC score	0.073764 (rank : 114)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	205	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

DDEF2_MOUSE
NC score	0.073674 (rank : 115)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	205	Target Neighborhood Hits	625	Shared Neighborhood Hits	74
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ABI3_HUMAN
NC score	0.073615 (rank : 116)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	205	Target Neighborhood Hits	227	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

PRB3_HUMAN
NC score	0.073506 (rank : 117)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	205	Target Neighborhood Hits	318	Shared Neighborhood Hits	35
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

ARHG6_HUMAN
NC score	0.073427 (rank : 118)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	205	Target Neighborhood Hits	376	Shared Neighborhood Hits	58
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

STAC3_HUMAN
NC score	0.073292 (rank : 119)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	205	Target Neighborhood Hits	228	Shared Neighborhood Hits	55
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

MUC7_HUMAN
NC score	0.072380 (rank : 120)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	205	Target Neighborhood Hits	538	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

VAV_HUMAN
NC score	0.071704 (rank : 121)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	205	Target Neighborhood Hits	452	Shared Neighborhood Hits	64
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

PACN3_HUMAN
NC score	0.070415 (rank : 122)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	205	Target Neighborhood Hits	385	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

VAV2_HUMAN
NC score	0.070179 (rank : 123)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	205	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV_MOUSE
NC score	0.070080 (rank : 124)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	205	Target Neighborhood Hits	430	Shared Neighborhood Hits	64
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

WASIP_MOUSE
NC score	0.069892 (rank : 125)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	205	Target Neighborhood Hits	392	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

VAV2_MOUSE
NC score	0.069809 (rank : 126)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	205	Target Neighborhood Hits	456	Shared Neighborhood Hits	60
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

BAT2_HUMAN
NC score	0.069280 (rank : 127)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	205	Target Neighborhood Hits	931	Shared Neighborhood Hits	68
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NEBL_HUMAN
NC score	0.069264 (rank : 128)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	205	Target Neighborhood Hits	457	Shared Neighborhood Hits	53
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

PEX13_HUMAN
NC score	0.069254 (rank : 129)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	205	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
NC score	0.069078 (rank : 130)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	205	Target Neighborhood Hits	126	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

SRRM2_MOUSE
NC score	0.068587 (rank : 131)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	205	Target Neighborhood Hits	1470	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

OGFR_HUMAN
NC score	0.068004 (rank : 132)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	205	Target Neighborhood Hits	1582	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SHLB1_HUMAN
NC score	0.067887 (rank : 133)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	205	Target Neighborhood Hits	96	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

TARA_HUMAN
NC score	0.067259 (rank : 134)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	205	Target Neighborhood Hits	1626	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SHLB1_MOUSE
NC score	0.066758 (rank : 135)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	205	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

DDEF2_HUMAN
NC score	0.066653 (rank : 136)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	205	Target Neighborhood Hits	599	Shared Neighborhood Hits	79
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SRRM1_HUMAN
NC score	0.065978 (rank : 137)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	205	Target Neighborhood Hits	690	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

NEBU_HUMAN
NC score	0.064745 (rank : 138)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	205	Target Neighborhood Hits	420	Shared Neighborhood Hits	60
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

VAV3_HUMAN
NC score	0.064615 (rank : 139)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	205	Target Neighborhood Hits	398	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

NOXO1_MOUSE
NC score	0.064367 (rank : 140)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	205	Target Neighborhood Hits	114	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

ALO17_HUMAN
NC score	0.063780 (rank : 141)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	205	Target Neighborhood Hits	317	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

VAV3_MOUSE
NC score	0.063664 (rank : 142)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	205	Target Neighborhood Hits	404	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

GSCR1_HUMAN
NC score	0.063161 (rank : 143)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	205	Target Neighborhood Hits	674	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

BAT2_MOUSE
NC score	0.062369 (rank : 144)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	205	Target Neighborhood Hits	947	Shared Neighborhood Hits	71
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PCQAP_HUMAN
NC score	0.062192 (rank : 145)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	205	Target Neighborhood Hits	549	Shared Neighborhood Hits	51
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

LRC56_HUMAN
NC score	0.061473 (rank : 146)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	205	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

ATN1_HUMAN
NC score	0.061048 (rank : 147)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	205	Target Neighborhood Hits	676	Shared Neighborhood Hits	57
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ARHG4_MOUSE
NC score	0.060126 (rank : 148)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	205	Target Neighborhood Hits	185	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CTDP1_HUMAN
NC score	0.060057 (rank : 149)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	205	Target Neighborhood Hits	416	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

PLCG2_HUMAN
NC score	0.059687 (rank : 150)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	205	Target Neighborhood Hits	280	Shared Neighborhood Hits	58
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PLCG1_MOUSE
NC score	0.059157 (rank : 151)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	205	Target Neighborhood Hits	314	Shared Neighborhood Hits	57
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PRP1_HUMAN
NC score	0.059002 (rank : 152)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	205	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SLAP2_HUMAN
NC score	0.058738 (rank : 153)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	205	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SFR15_HUMAN
NC score	0.058216 (rank : 154)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	205	Target Neighborhood Hits	368	Shared Neighborhood Hits	32
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SLAP2_MOUSE
NC score	0.057507 (rank : 155)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	205	Target Neighborhood Hits	136	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

PRG4_HUMAN
NC score	0.056932 (rank : 156)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	205	Target Neighborhood Hits	764	Shared Neighborhood Hits	56
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

NCOA6_HUMAN
NC score	0.056881 (rank : 157)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	205	Target Neighborhood Hits	1202	Shared Neighborhood Hits	69
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SRRM2_HUMAN
NC score	0.056633 (rank : 158)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	205	Target Neighborhood Hits	1296	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CIC_HUMAN
NC score	0.056217 (rank : 159)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	205	Target Neighborhood Hits	992	Shared Neighborhood Hits	63
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ES8L3_MOUSE
NC score	0.056165 (rank : 160)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	205	Target Neighborhood Hits	168	Shared Neighborhood Hits	56
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

SYN1_MOUSE
NC score	0.055890 (rank : 161)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	205	Target Neighborhood Hits	363	Shared Neighborhood Hits	52
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SNX18_MOUSE
NC score	0.055651 (rank : 162)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	205	Target Neighborhood Hits	198	Shared Neighborhood Hits	45
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

GGN_HUMAN
NC score	0.055533 (rank : 163)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	205	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

WASIP_HUMAN
NC score	0.055498 (rank : 164)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	205	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

MARCS_MOUSE
NC score	0.055280 (rank : 165)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	205	Target Neighborhood Hits	227	Shared Neighborhood Hits	27
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

SYN1_HUMAN
NC score	0.054607 (rank : 166)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	205	Target Neighborhood Hits	419	Shared Neighborhood Hits	57
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SNX18_HUMAN
NC score	0.054474 (rank : 167)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	205	Target Neighborhood Hits	207	Shared Neighborhood Hits	45
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

PLCG1_HUMAN
NC score	0.054473 (rank : 168)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	205	Target Neighborhood Hits	293	Shared Neighborhood Hits	56
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

NACAM_MOUSE
NC score	0.054053 (rank : 169)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	205	Target Neighborhood Hits	1866	Shared Neighborhood Hits	93
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CN155_HUMAN
NC score	0.053882 (rank : 170)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	205	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

LNK_HUMAN
NC score	0.053556 (rank : 171)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	205	Target Neighborhood Hits	151	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

PRP2_MOUSE
NC score	0.053405 (rank : 172)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	205	Target Neighborhood Hits	347	Shared Neighborhood Hits	37
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SYP2L_HUMAN
NC score	0.053362 (rank : 173)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	205	Target Neighborhood Hits	400	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

GPTC8_HUMAN
NC score	0.053172 (rank : 174)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	205	Target Neighborhood Hits	366	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

CBP_MOUSE
NC score	0.053169 (rank : 175)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	205	Target Neighborhood Hits	1051	Shared Neighborhood Hits	65
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BASP_MOUSE
NC score	0.053150 (rank : 176)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	205	Target Neighborhood Hits	260	Shared Neighborhood Hits	31
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BSN_HUMAN
NC score	0.053082 (rank : 177)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	205	Target Neighborhood Hits	1537	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

EP300_HUMAN
NC score	0.053079 (rank : 178)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	205	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

DDEF1_MOUSE
NC score	0.052742 (rank : 179)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	205	Target Neighborhood Hits	592	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

RERE_MOUSE
NC score	0.052432 (rank : 180)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	205	Target Neighborhood Hits	785	Shared Neighborhood Hits	55
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

BSN_MOUSE
NC score	0.052140 (rank : 181)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	205	Target Neighborhood Hits	2057	Shared Neighborhood Hits	95
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NOXO1_HUMAN
NC score	0.051628 (rank : 182)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	205	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

3BP1_HUMAN
NC score	0.051545 (rank : 183)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	205	Target Neighborhood Hits	376	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

PRG4_MOUSE
NC score	0.051351 (rank : 184)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	205	Target Neighborhood Hits	624	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRB4S_HUMAN
NC score	0.051083 (rank : 185)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	205	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRR12_HUMAN
NC score	0.050842 (rank : 186)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	205	Target Neighborhood Hits	460	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RGS3_MOUSE
NC score	0.050835 (rank : 187)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	205	Target Neighborhood Hits	1621	Shared Neighborhood Hits	78
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CF150_HUMAN
NC score	0.050651 (rank : 188)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	205	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N884, Q32NC9, Q5SWL0, Q5SWL1, Q96E45	Gene names	C6orf150
Domain Architecture	No domain graphic available
Description	Protein C6orf150.

CO039_HUMAN
NC score	0.050371 (rank : 189)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	205	Target Neighborhood Hits	264	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

PDZD2_HUMAN
NC score	0.050275 (rank : 190)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	205	Target Neighborhood Hits	772	Shared Neighborhood Hits	51
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SMG7_MOUSE
NC score	0.050149 (rank : 191)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	205	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

GRIN1_MOUSE
NC score	0.049885 (rank : 192)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	205	Target Neighborhood Hits	337	Shared Neighborhood Hits	37
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MAGE1_HUMAN
NC score	0.049791 (rank : 193)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	205	Target Neighborhood Hits	1389	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

DOS_HUMAN
NC score	0.049127 (rank : 194)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	205	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

MLL3_HUMAN
NC score	0.047190 (rank : 195)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	205	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

FYN_MOUSE
NC score	0.045422 (rank : 196)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	205	Target Neighborhood Hits	1073	Shared Neighborhood Hits	71
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

NFH_MOUSE
NC score	0.045259 (rank : 197)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	205	Target Neighborhood Hits	2247	Shared Neighborhood Hits	89
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TCF19_MOUSE
NC score	0.045069 (rank : 198)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	205	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

FYN_HUMAN
NC score	0.044903 (rank : 199)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	205	Target Neighborhood Hits	1078	Shared Neighborhood Hits	71
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

SETBP_MOUSE
NC score	0.042429 (rank : 200)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	205	Target Neighborhood Hits	352	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

RECQ5_HUMAN
NC score	0.041625 (rank : 201)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	205	Target Neighborhood Hits	390	Shared Neighborhood Hits	31
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

ZAR1_MOUSE
NC score	0.041547 (rank : 202)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	205	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

JPH2_HUMAN
NC score	0.041515 (rank : 203)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	205	Target Neighborhood Hits	639	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

ABL1_MOUSE
NC score	0.040687 (rank : 204)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	205	Target Neighborhood Hits	1178	Shared Neighborhood Hits	73
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_HUMAN
NC score	0.040187 (rank : 205)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	205	Target Neighborhood Hits	1220	Shared Neighborhood Hits	74
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

DOT1L_HUMAN
NC score	0.038246 (rank : 206)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	205	Target Neighborhood Hits	660	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

SON_MOUSE
NC score	0.037715 (rank : 207)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	205	Target Neighborhood Hits	957	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

PK1L1_HUMAN
NC score	0.037331 (rank : 208)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	205	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

CAC1G_HUMAN
NC score	0.037166 (rank : 209)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	205	Target Neighborhood Hits	587	Shared Neighborhood Hits	34
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

TS13_MOUSE
NC score	0.036946 (rank : 210)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	205	Target Neighborhood Hits	191	Shared Neighborhood Hits	7
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

BAZ2A_MOUSE
NC score	0.036906 (rank : 211)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	205	Target Neighborhood Hits	744	Shared Neighborhood Hits	51
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

TXK_MOUSE
NC score	0.036222 (rank : 212)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	205	Target Neighborhood Hits	980	Shared Neighborhood Hits	62
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

T22D4_HUMAN
NC score	0.036194 (rank : 213)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	205	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

USH1C_MOUSE
NC score	0.036089 (rank : 214)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	205	Target Neighborhood Hits	557	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ABL2_HUMAN
NC score	0.036032 (rank : 215)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	205	Target Neighborhood Hits	1045	Shared Neighborhood Hits	53
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ZN750_MOUSE
NC score	0.035991 (rank : 216)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	205	Target Neighborhood Hits	346	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

PERQ1_MOUSE
NC score	0.035462 (rank : 217)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	205	Target Neighborhood Hits	215	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

MYCD_MOUSE
NC score	0.033842 (rank : 218)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	205	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

MPP5_HUMAN
NC score	0.033495 (rank : 219)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	205	Target Neighborhood Hits	231	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.033299 (rank : 220)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	205	Target Neighborhood Hits	226	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

HNF1A_HUMAN
NC score	0.033102 (rank : 221)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	205	Target Neighborhood Hits	193	Shared Neighborhood Hits	14
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

SC24C_HUMAN
NC score	0.032981 (rank : 222)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	205	Target Neighborhood Hits	662	Shared Neighborhood Hits	36
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

LCK_HUMAN
NC score	0.032336 (rank : 223)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	205	Target Neighborhood Hits	987	Shared Neighborhood Hits	46
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

K1683_HUMAN
NC score	0.031837 (rank : 224)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	205	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

LCK_MOUSE
NC score	0.031352 (rank : 225)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	205	Target Neighborhood Hits	981	Shared Neighborhood Hits	45
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

MATK_HUMAN
NC score	0.030211 (rank : 226)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	205	Target Neighborhood Hits	954	Shared Neighborhood Hits	42
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

ZYX_HUMAN
NC score	0.030079 (rank : 227)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	205	Target Neighborhood Hits	387	Shared Neighborhood Hits	35
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

RRBP1_MOUSE
NC score	0.029725 (rank : 228)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	205	Target Neighborhood Hits	1650	Shared Neighborhood Hits	52
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

GCC1_MOUSE
NC score	0.028521 (rank : 229)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	205	Target Neighborhood Hits	777	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

SSBP4_HUMAN
NC score	0.028355 (rank : 230)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	205	Target Neighborhood Hits	753	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

FMN1B_MOUSE
NC score	0.028110 (rank : 231)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	205	Target Neighborhood Hits	447	Shared Neighborhood Hits	39
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

SRMS_HUMAN
NC score	0.027915 (rank : 232)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	205	Target Neighborhood Hits	946	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

CU002_HUMAN
NC score	0.026613 (rank : 233)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	205	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	O43822, O14993, Q99837, Q99838	Gene names	C21orf2
Domain Architecture	No domain graphic available
Description	Protein C21orf2 (C21orf-HUMF09G8.5) (YF5/A2).

ANK2_HUMAN
NC score	0.026336 (rank : 234)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	205	Target Neighborhood Hits	1615	Shared Neighborhood Hits	67
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

HNF1A_MOUSE
NC score	0.026222 (rank : 235)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	205	Target Neighborhood Hits	212	Shared Neighborhood Hits	15
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

SNPC2_MOUSE
NC score	0.025965 (rank : 236)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	205	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

MPRI_MOUSE
NC score	0.025956 (rank : 237)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	205	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

CAC1A_MOUSE
NC score	0.025934 (rank : 238)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	205	Target Neighborhood Hits	267	Shared Neighborhood Hits	21
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_HUMAN
NC score	0.025000 (rank : 239)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	205	Target Neighborhood Hits	387	Shared Neighborhood Hits	25
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

MPRI_HUMAN
NC score	0.024900 (rank : 240)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	205	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

SMG5_HUMAN
NC score	0.024835 (rank : 241)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	205	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

ADA2B_MOUSE
NC score	0.024645 (rank : 242)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	205	Target Neighborhood Hits	891	Shared Neighborhood Hits	7
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).

B4GT1_HUMAN
NC score	0.023840 (rank : 243)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	205	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

S1769_HUMAN
NC score	0.023484 (rank : 244)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	205	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q99871, Q96HS8, Q9NP54	Gene names	UIP1
Domain Architecture	No domain graphic available
Description	26S proteasome-associated UCH37-interacting protein 1 (X-linked protein STS1769).

EPN3_MOUSE
NC score	0.023410 (rank : 245)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	205	Target Neighborhood Hits	312	Shared Neighborhood Hits	29
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

ARNT_MOUSE
NC score	0.023370 (rank : 246)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	205	Target Neighborhood Hits	213	Shared Neighborhood Hits	15
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NIPBL_HUMAN
NC score	0.023255 (rank : 247)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	205	Target Neighborhood Hits	1311	Shared Neighborhood Hits	48
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TRIO_HUMAN
NC score	0.023010 (rank : 248)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	205	Target Neighborhood Hits	1580	Shared Neighborhood Hits	63
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

FA21C_HUMAN
NC score	0.022882 (rank : 249)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	205	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

PHLPP_HUMAN
NC score	0.022516 (rank : 250)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	205	Target Neighborhood Hits	604	Shared Neighborhood Hits	33
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

IQEC3_MOUSE
NC score	0.022411 (rank : 251)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	205	Target Neighborhood Hits	274	Shared Neighborhood Hits	24
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

STK10_HUMAN
NC score	0.021766 (rank : 252)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	205	Target Neighborhood Hits	1921	Shared Neighborhood Hits	47
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

NCOA2_HUMAN
NC score	0.021701 (rank : 253)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	205	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

HCN4_HUMAN
NC score	0.021616 (rank : 254)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	205	Target Neighborhood Hits	303	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

TTBK1_HUMAN
NC score	0.021542 (rank : 255)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	205	Target Neighborhood Hits	1058	Shared Neighborhood Hits	47
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

BRD8_MOUSE
NC score	0.020789 (rank : 256)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	205	Target Neighborhood Hits	422	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

TENN_MOUSE
NC score	0.020783 (rank : 257)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	205	Target Neighborhood Hits	484	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CRSP7_HUMAN
NC score	0.020550 (rank : 258)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	205	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CK016_MOUSE
NC score	0.020208 (rank : 259)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	205	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJR6, Q80XE7	Gene names	D7h11orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf16 homolog.

LARP4_MOUSE
NC score	0.019978 (rank : 260)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	205	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

PTTG1_MOUSE
NC score	0.019223 (rank : 261)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	205	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQJ7, O88887, Q9Z2E6	Gene names	Pttg1, Pttg
Domain Architecture
Description	Securin (Pituitary tumor-transforming protein 1).

TBX21_MOUSE
NC score	0.019131 (rank : 262)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	205	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

CF064_HUMAN
NC score	0.019089 (rank : 263)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	205	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPB0, Q9H0D8	Gene names	C6orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf64.

CSPG3_MOUSE
NC score	0.019076 (rank : 264)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	205	Target Neighborhood Hits	657	Shared Neighborhood Hits	29
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TBC20_MOUSE
NC score	0.018182 (rank : 265)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	205	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9I4, Q3TYW9, Q99LW2	Gene names	Tbc1d20
Domain Architecture
Description	TBC1 domain family member 20.

TBC20_HUMAN
NC score	0.018128 (rank : 266)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	205	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q96BZ9, Q5JWQ7, Q96NE1, Q9BYM7, Q9H140	Gene names	TBC1D20, C20orf140
Domain Architecture
Description	TBC1 domain family member 20.

CAR10_HUMAN
NC score	0.017926 (rank : 267)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	205	Target Neighborhood Hits	569	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

OTU7A_MOUSE
NC score	0.017446 (rank : 268)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	205	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

ERBB2_HUMAN
NC score	0.017382 (rank : 269)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	205	Target Neighborhood Hits	1073	Shared Neighborhood Hits	25
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

CCD22_HUMAN
NC score	0.017337 (rank : 270)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	205	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

ADA2B_HUMAN
NC score	0.016794 (rank : 271)	θ value	0.00869519 (rank : 14)
Query Neighborhood Hits	205	Target Neighborhood Hits	881	Shared Neighborhood Hits	5
SwissProt Accessions	P18089, Q4TUH9, Q53RF2, Q9BZK0	Gene names	ADRA2B
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor) (Alpha-2 adrenergic receptor subtype C2).

MINK1_HUMAN
NC score	0.016595 (rank : 272)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	205	Target Neighborhood Hits	1477	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

TULP4_HUMAN
NC score	0.016462 (rank : 273)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	205	Target Neighborhood Hits	426	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ACH10_HUMAN
NC score	0.016105 (rank : 274)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	205	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZZ6	Gene names	CHRNA10, NACHRA10
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-10 precursor (Nicotinic acetylcholine receptor subunit alpha 10) (NACHR alpha 10).

AIRE_MOUSE
NC score	0.015770 (rank : 275)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	205	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

WDR46_MOUSE
NC score	0.015580 (rank : 276)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	205	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

UBP28_MOUSE
NC score	0.015476 (rank : 277)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	205	Target Neighborhood Hits	178	Shared Neighborhood Hits	5
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

RN166_MOUSE
NC score	0.015455 (rank : 278)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	205	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

OSBP2_HUMAN
NC score	0.014883 (rank : 279)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	205	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

RPGF6_HUMAN
NC score	0.014757 (rank : 280)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	205	Target Neighborhood Hits	266	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PCNT_MOUSE
NC score	0.014477 (rank : 281)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	205	Target Neighborhood Hits	1207	Shared Neighborhood Hits	33
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RN166_HUMAN
NC score	0.014408 (rank : 282)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	205	Target Neighborhood Hits	240	Shared Neighborhood Hits	4
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

MYLK2_HUMAN
NC score	0.013447 (rank : 283)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	205	Target Neighborhood Hits	920	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

SMAL1_HUMAN
NC score	0.013266 (rank : 284)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	205	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

PZRN3_HUMAN
NC score	0.012505 (rank : 285)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	205	Target Neighborhood Hits	461	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RASF7_MOUSE
NC score	0.011874 (rank : 286)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	205	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

MYLK_MOUSE
NC score	0.011844 (rank : 287)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	205	Target Neighborhood Hits	1489	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MOCOS_MOUSE
NC score	0.011296 (rank : 288)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	205	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q14CH1	Gene names	Mocos
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS).

ANR38_MOUSE
NC score	0.010931 (rank : 289)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	205	Target Neighborhood Hits	512	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

HXD3_HUMAN
NC score	0.010114 (rank : 290)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	205	Target Neighborhood Hits	433	Shared Neighborhood Hits	17
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

CSPG2_MOUSE
NC score	0.010035 (rank : 291)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	205	Target Neighborhood Hits	711	Shared Neighborhood Hits	20
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

B3A3_MOUSE
NC score	0.009814 (rank : 292)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	205	Target Neighborhood Hits	112	Shared Neighborhood Hits	10
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

NAR1_HUMAN
NC score	0.009582 (rank : 293)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	205	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P52961, Q96KT9	Gene names	ART1
Domain Architecture
Description	GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 precursor (EC 2.4.2.31) (Mono(ADP-ribosyl)transferase) (CD296 antigen).

AMOL1_HUMAN
NC score	0.009240 (rank : 294)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	205	Target Neighborhood Hits	435	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

NPTX2_MOUSE
NC score	0.008973 (rank : 295)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	205	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	O70340	Gene names	Nptx2
Domain Architecture
Description	Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II).

HXD3_MOUSE
NC score	0.008946 (rank : 296)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	205	Target Neighborhood Hits	435	Shared Neighborhood Hits	17
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

MAST2_HUMAN
NC score	0.008787 (rank : 297)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	205	Target Neighborhood Hits	1189	Shared Neighborhood Hits	44
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MICA2_HUMAN
NC score	0.008732 (rank : 298)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	205	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

NFKB2_MOUSE
NC score	0.008728 (rank : 299)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	205	Target Neighborhood Hits	326	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

RASF5_HUMAN
NC score	0.008312 (rank : 300)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	205	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

E41L2_HUMAN
NC score	0.007042 (rank : 301)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	205	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

NMD3B_HUMAN
NC score	0.006956 (rank : 302)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	205	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

DLL1_HUMAN
NC score	0.006868 (rank : 303)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	205	Target Neighborhood Hits	455	Shared Neighborhood Hits	8
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

ITB7_HUMAN
NC score	0.006295 (rank : 304)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	205	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LIRB4_HUMAN
NC score	0.005279 (rank : 305)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	205	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHJ6, O15468, O75021, Q8N1C7, Q8NHL5	Gene names	LILRB4, ILT3, LIR5
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Immunoglobulin- like transcript 3) (ILT-3) (Monocyte inhibitory receptor HM18) (CD85k antigen).

LRIG3_MOUSE
NC score	0.005082 (rank : 306)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	205	Target Neighborhood Hits	611	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

ZN516_MOUSE
NC score	0.004918 (rank : 307)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	205	Target Neighborhood Hits	1197	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

BACH1_HUMAN
NC score	0.004105 (rank : 308)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	205	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

PCDA8_HUMAN
NC score	0.002792 (rank : 309)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	205	Target Neighborhood Hits	187	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

CELR3_HUMAN
NC score	0.001961 (rank : 310)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	205	Target Neighborhood Hits	680	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

ZSCA5_HUMAN
NC score	0.000236 (rank : 311)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	205	Target Neighborhood Hits	862	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

KLF17_MOUSE
NC score	-0.001877 (rank : 312)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	205	Target Neighborhood Hits	684	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CFA7, Q3UT30, Q6P233, Q9D351	Gene names	Klf17, Gzf, Zfp393, Znf393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393) (Germ cell-specific zinc finger protein).

ZSCA4_HUMAN
NC score	-0.002268 (rank : 313)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	205	Target Neighborhood Hits	713	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NAM6	Gene names	ZSCAN4, ZNF494
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494).