Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : MYCD_MOUSE

For an explanation of this page, click here

MYCD_MOUSE
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MYCD_HUMAN
θ value	0 (rank : 1)	NC score	0.948653 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	167	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

MYCD_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

MKL2_HUMAN
θ value	7.44272e-79 (rank : 3)	NC score	0.831993 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

MKL1_HUMAN
θ value	1.15091e-71 (rank : 4)	NC score	0.839745 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	232	Shared Neighborhood Hits	30
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MKL2_MOUSE
θ value	5.17823e-64 (rank : 5)	NC score	0.832556 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

MKL1_MOUSE
θ value	3.84914e-51 (rank : 6)	NC score	0.750030 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	667	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MAML1_HUMAN
θ value	0.000461057 (rank : 7)	NC score	0.087328 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

WNK1_HUMAN
θ value	0.00102713 (rank : 8)	NC score	0.021580 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	1158	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

PO6F2_HUMAN
θ value	0.0252991 (rank : 9)	NC score	0.046602 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	618	Shared Neighborhood Hits	30
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

SAFB1_HUMAN
θ value	0.0330416 (rank : 10)	NC score	0.106884 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	493	Shared Neighborhood Hits	19
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

TCOF_MOUSE
θ value	0.0431538 (rank : 11)	NC score	0.061922 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	471	Shared Neighborhood Hits	26
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

PCNT_MOUSE
θ value	0.0736092 (rank : 12)	NC score	0.024752 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	1207	Shared Neighborhood Hits	26
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PO6F2_MOUSE
θ value	0.0736092 (rank : 13)	NC score	0.057242 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	639	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

ANK2_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.040187 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	1615	Shared Neighborhood Hits	65
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CN145_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.018737 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	1196	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

PHC3_MOUSE
θ value	0.0961366 (rank : 16)	NC score	0.067067 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

HCN4_MOUSE
θ value	0.125558 (rank : 17)	NC score	0.033915 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MLL3_HUMAN
θ value	0.125558 (rank : 18)	NC score	0.058924 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	1644	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PHAR3_MOUSE
θ value	0.163984 (rank : 19)	NC score	0.082851 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	206	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PHC3_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.066784 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	218	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

MAML2_HUMAN
θ value	0.21417 (rank : 21)	NC score	0.076886 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

NCOA6_HUMAN
θ value	0.21417 (rank : 22)	NC score	0.071177 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	1202	Shared Neighborhood Hits	57
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MOR2A_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.041076 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	220	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

LIPS_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.052033 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	314	Shared Neighborhood Hits	30
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

OGFR_MOUSE
θ value	0.365318 (rank : 25)	NC score	0.044881 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	584	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

EVI1_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.003073 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	924	Shared Neighborhood Hits	13
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

FA8A1_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.093420 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

ASXL1_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.034919 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	182	Shared Neighborhood Hits	14
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CJ012_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.045656 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	467	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CK035_MOUSE
θ value	0.62314 (rank : 30)	NC score	0.040699 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q0VET5, Q9CW10	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35 homolog.

HNRPU_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.137113 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

SC24C_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.042112 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	662	Shared Neighborhood Hits	40
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ZEP2_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.010684 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	937	Shared Neighborhood Hits	20
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

AMER1_HUMAN
θ value	0.813845 (rank : 34)	NC score	0.038772 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4X0, Q6P9D8, Q8WX22, Q9UIQ8	Gene names	AMMECR1
Domain Architecture
Description	AMME syndrome candidate gene 1 protein.

CREB5_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.032761 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	222	Shared Neighborhood Hits	16
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

DREB_MOUSE
θ value	0.813845 (rank : 36)	NC score	0.031646 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	446	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MO4L1_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.030554 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

NEDD1_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.019317 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	294	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

NOTC1_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.006167 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SAFB2_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.077634 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	720	Shared Neighborhood Hits	28
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SAFB2_MOUSE
θ value	0.813845 (rank : 41)	NC score	0.097357 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	581	Shared Neighborhood Hits	25
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

UBP37_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.024726 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	9
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

ARRD1_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.030443 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ATBF1_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.023213 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	1547	Shared Neighborhood Hits	38
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BCL9_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.060333 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	1008	Shared Neighborhood Hits	55
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CCD1A_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.036107 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

CD44_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.030163 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	P15379, Q05732, Q61395, Q62060, Q62061, Q62062, Q62063, Q62408, Q62409, Q64296, Q99J14, Q9QYX8	Gene names	Cd44, Ly-24
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein 1) (PGP-1) (HUTCH-I) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen Ly-24).

GGA1_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.023899 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

K0157_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.032661 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q15018, Q96H11	Gene names	KIAA0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

KCNH6_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.018864 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

NCOA6_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.074501 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	1076	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SRRM2_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.040415 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	1470	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WNK1_MOUSE
θ value	1.06291 (rank : 53)	NC score	0.017387 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	1179	Shared Neighborhood Hits	29
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

HNRL1_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.094944 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	173	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

MAGE1_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.037572 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	1389	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MLL3_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.052942 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	1399	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RFX1_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.025271 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	256	Shared Neighborhood Hits	22
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SMRC2_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.032540 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	487	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TROAP_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.068444 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

DCP1A_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.038557 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

GOGA4_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.022247 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	1939	Shared Neighborhood Hits	44
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GP73_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.031664 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

HNRL1_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.087618 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

PDZD2_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.023236 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	772	Shared Neighborhood Hits	26
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

WASF2_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.033252 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	280	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

ATX2L_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.056676 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	443	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BCL9_MOUSE
θ value	2.36792 (rank : 67)	NC score	0.050181 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	770	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

EPAS1_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.011391 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HCC1_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.154451 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D1J3, Q3UJZ4, Q9CU18	Gene names	Hcc1
Domain Architecture
Description	Nuclear protein Hcc-1.

OXR1_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.020662 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	282	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

SOX9_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.013566 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	210	Shared Neighborhood Hits	13
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SYNG_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.031666 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	206	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TTC3_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.020892 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	664	Shared Neighborhood Hits	20
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

ACINU_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.055511 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	828	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.058384 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	712	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

DIDO1_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.029135 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	960	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ELK1_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.011288 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

FA5_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.014226 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FETUB_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.022201 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

FOXJ3_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.013292 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	190	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

HGS_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.032854 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	589	Shared Neighborhood Hits	37
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

LAD1_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.029652 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	391	Shared Neighborhood Hits	23
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MORC2_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.037766 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

NFAT5_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.028047 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	217	Shared Neighborhood Hits	18
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

NR4A3_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.007168 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

RYR2_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.020946 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

ATBF1_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.022349 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	1841	Shared Neighborhood Hits	44
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATN1_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.046734 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	676	Shared Neighborhood Hits	42
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BMP2K_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.004709 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CAR10_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.014064 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	569	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

FOXJ2_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.013371 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	239	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

HGS_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.029800 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	517	Shared Neighborhood Hits	32
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

IREB2_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.016742 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P48200, Q13095	Gene names	IREB2
Domain Architecture
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

KBTBB_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.009342 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BNW9	Gene names	Kbtbd11, Kiaa0711
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 11.

MO4L1_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.024672 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

RUSC2_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.033842 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

TEF_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.014775 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q10587, Q15729, Q7Z3J7, Q8IU94, Q96TG4	Gene names	TEF
Domain Architecture
Description	Thyrotroph embryonic factor.

CM007_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.014946 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	422	Shared Neighborhood Hits	10
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

HCC1_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.146189 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	P82979, Q9P066	Gene names	HCC1
Domain Architecture
Description	Nuclear protein Hcc-1 (Proliferation-associated cytokine-inducible protein CIP29) (Cytokine-induced protein of 29 kDa).

M4K4_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.003805 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	1589	Shared Neighborhood Hits	29
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MOR2B_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.030627 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C5W4, Q8CG24	Gene names	Morc2b, Tce6
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2B (TCE6).

OFD1_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.021017 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	753	Shared Neighborhood Hits	21
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

PREP_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.016407 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K411, Q3THC4, Q3TJI1, Q3TPP0, Q3URQ8, Q4KUG2, Q4KUG3, Q6ZPX6, Q922N1, Q9CV63	Gene names	Pitrm1, Kiaa1104, Ntup1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (Pitrilysin metalloproteinase 1).

RNF8_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.011273 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	618	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SEPT4_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.006142 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	P28661, Q5ND15	Gene names	Sept4, Pnutl2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5).

SYNG_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.028527 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	160	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TRI46_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.007922 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	291	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

XRN1_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.012830 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

AFF4_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.018225 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CASP_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.011712 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	1131	Shared Neighborhood Hits	29
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CN092_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.017651 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CNGB1_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.016505 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	222	Shared Neighborhood Hits	17
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

EAF1_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.015311 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

EEA1_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.009988 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	1637	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EP400_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.021495 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

LRC45_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.009869 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	959	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LUZP1_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.010282 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	940	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MUC5B_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.019624 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	1020	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PPE2_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.007241 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O14830, O14831	Gene names	PPEF2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

RGS3_MOUSE
θ value	6.88961 (rank : 120)	NC score	0.047429 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	1621	Shared Neighborhood Hits	73
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SASH1_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.011431 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	292	Shared Neighborhood Hits	12
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SI1L1_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.007857 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

TAU_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.021878 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	448	Shared Neighborhood Hits	25
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TRI56_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.008103 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	255	Shared Neighborhood Hits	8
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

UBQL2_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.015856 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

ZN438_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.010344 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ARI1B_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.038507 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	567	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ASPP2_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.013957 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	1156	Shared Neighborhood Hits	40
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ATX2L_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.035108 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	401	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

BRDT_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.007657 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CCD21_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.018357 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CN092_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.016364 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	143	Shared Neighborhood Hits	12
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CU013_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.011411 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	405	Shared Neighborhood Hits	11
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

FNDC3_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.003953 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

IREB2_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.014094 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q811J3, O70235	Gene names	Ireb2, Irp2
Domain Architecture	No domain graphic available
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

K1267_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.012150 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

MDC1_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.041927 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	1446	Shared Neighborhood Hits	61
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PCSK7_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.005278 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

PMS2_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.009502 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

SOX9_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.016487 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SRBS1_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.023809 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STABP_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.010577 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	191	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

TTLL4_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.010293 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

ZN335_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.000081 (rank : 152)
Query Neighborhood Hits	144	Target Neighborhood Hits	973	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

MAML1_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.058116 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

NACAM_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.055205 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	1866	Shared Neighborhood Hits	73
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PHAR1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.050668 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

PHAR1_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.051257 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

PHAR2_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.071873 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

PHAR3_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.069479 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

SELPL_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.054259 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	588	Shared Neighborhood Hits	37
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ZCH10_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.059318 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

Hits sorted by NC score

MYCD_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

MYCD_HUMAN
NC score	0.948653 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	167	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

MKL1_HUMAN
NC score	0.839745 (rank : 3)	θ value	1.15091e-71 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	232	Shared Neighborhood Hits	30
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MKL2_MOUSE
NC score	0.832556 (rank : 4)	θ value	5.17823e-64 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

MKL2_HUMAN
NC score	0.831993 (rank : 5)	θ value	7.44272e-79 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

MKL1_MOUSE
NC score	0.750030 (rank : 6)	θ value	3.84914e-51 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	667	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

HCC1_MOUSE
NC score	0.154451 (rank : 7)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D1J3, Q3UJZ4, Q9CU18	Gene names	Hcc1
Domain Architecture
Description	Nuclear protein Hcc-1.

HCC1_HUMAN
NC score	0.146189 (rank : 8)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	P82979, Q9P066	Gene names	HCC1
Domain Architecture
Description	Nuclear protein Hcc-1 (Proliferation-associated cytokine-inducible protein CIP29) (Cytokine-induced protein of 29 kDa).

HNRPU_HUMAN
NC score	0.137113 (rank : 9)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

SAFB1_HUMAN
NC score	0.106884 (rank : 10)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	493	Shared Neighborhood Hits	19
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

SAFB2_MOUSE
NC score	0.097357 (rank : 11)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	581	Shared Neighborhood Hits	25
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

HNRL1_HUMAN
NC score	0.094944 (rank : 12)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	173	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

FA8A1_HUMAN
NC score	0.093420 (rank : 13)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

HNRL1_MOUSE
NC score	0.087618 (rank : 14)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

MAML1_HUMAN
NC score	0.087328 (rank : 15)	θ value	0.000461057 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PHAR3_MOUSE
NC score	0.082851 (rank : 16)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	206	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

SAFB2_HUMAN
NC score	0.077634 (rank : 17)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	720	Shared Neighborhood Hits	28
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

MAML2_HUMAN
NC score	0.076886 (rank : 18)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

NCOA6_MOUSE
NC score	0.074501 (rank : 19)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	1076	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PHAR2_HUMAN
NC score	0.071873 (rank : 20)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

NCOA6_HUMAN
NC score	0.071177 (rank : 21)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	1202	Shared Neighborhood Hits	57
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PHAR3_HUMAN
NC score	0.069479 (rank : 22)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

TROAP_HUMAN
NC score	0.068444 (rank : 23)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

PHC3_MOUSE
NC score	0.067067 (rank : 24)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

PHC3_HUMAN
NC score	0.066784 (rank : 25)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	218	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

TCOF_MOUSE
NC score	0.061922 (rank : 26)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	471	Shared Neighborhood Hits	26
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

BCL9_HUMAN
NC score	0.060333 (rank : 27)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	1008	Shared Neighborhood Hits	55
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

ZCH10_MOUSE
NC score	0.059318 (rank : 28)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	144	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

MLL3_HUMAN
NC score	0.058924 (rank : 29)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	1644	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ACINU_MOUSE
NC score	0.058384 (rank : 30)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	712	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MAML1_MOUSE
NC score	0.058116 (rank : 31)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PO6F2_MOUSE
NC score	0.057242 (rank : 32)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	639	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

ATX2L_HUMAN
NC score	0.056676 (rank : 33)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	443	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ACINU_HUMAN
NC score	0.055511 (rank : 34)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	828	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NACAM_MOUSE
NC score	0.055205 (rank : 35)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	1866	Shared Neighborhood Hits	73
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SELPL_MOUSE
NC score	0.054259 (rank : 36)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	588	Shared Neighborhood Hits	37
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

MLL3_MOUSE
NC score	0.052942 (rank : 37)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	1399	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

LIPS_HUMAN
NC score	0.052033 (rank : 38)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	314	Shared Neighborhood Hits	30
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

PHAR1_MOUSE
NC score	0.051257 (rank : 39)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

PHAR1_HUMAN
NC score	0.050668 (rank : 40)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

BCL9_MOUSE
NC score	0.050181 (rank : 41)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	770	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

RGS3_MOUSE
NC score	0.047429 (rank : 42)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	1621	Shared Neighborhood Hits	73
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ATN1_HUMAN
NC score	0.046734 (rank : 43)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	676	Shared Neighborhood Hits	42
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

PO6F2_HUMAN
NC score	0.046602 (rank : 44)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	618	Shared Neighborhood Hits	30
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

CJ012_HUMAN
NC score	0.045656 (rank : 45)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	467	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

OGFR_MOUSE
NC score	0.044881 (rank : 46)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	584	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SC24C_HUMAN
NC score	0.042112 (rank : 47)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	662	Shared Neighborhood Hits	40
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MDC1_HUMAN
NC score	0.041927 (rank : 48)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	1446	Shared Neighborhood Hits	61
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MOR2A_MOUSE
NC score	0.041076 (rank : 49)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	220	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

CK035_MOUSE
NC score	0.040699 (rank : 50)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q0VET5, Q9CW10	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35 homolog.

SRRM2_MOUSE
NC score	0.040415 (rank : 51)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	1470	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ANK2_HUMAN
NC score	0.040187 (rank : 52)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	1615	Shared Neighborhood Hits	65
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

AMER1_HUMAN
NC score	0.038772 (rank : 53)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4X0, Q6P9D8, Q8WX22, Q9UIQ8	Gene names	AMMECR1
Domain Architecture
Description	AMME syndrome candidate gene 1 protein.

DCP1A_HUMAN
NC score	0.038557 (rank : 54)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

ARI1B_HUMAN
NC score	0.038507 (rank : 55)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	567	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

MORC2_HUMAN
NC score	0.037766 (rank : 56)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

MAGE1_HUMAN
NC score	0.037572 (rank : 57)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	1389	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CCD1A_MOUSE
NC score	0.036107 (rank : 58)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

ATX2L_MOUSE
NC score	0.035108 (rank : 59)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	401	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

ASXL1_MOUSE
NC score	0.034919 (rank : 60)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	182	Shared Neighborhood Hits	14
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

HCN4_MOUSE
NC score	0.033915 (rank : 61)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

RUSC2_HUMAN
NC score	0.033842 (rank : 62)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

WASF2_HUMAN
NC score	0.033252 (rank : 63)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	280	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

HGS_MOUSE
NC score	0.032854 (rank : 64)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	589	Shared Neighborhood Hits	37
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CREB5_HUMAN
NC score	0.032761 (rank : 65)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	222	Shared Neighborhood Hits	16
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

K0157_HUMAN
NC score	0.032661 (rank : 66)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q15018, Q96H11	Gene names	KIAA0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

SMRC2_MOUSE
NC score	0.032540 (rank : 67)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	487	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SYNG_MOUSE
NC score	0.031666 (rank : 68)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	206	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

GP73_MOUSE
NC score	0.031664 (rank : 69)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

DREB_MOUSE
NC score	0.031646 (rank : 70)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	446	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MOR2B_MOUSE
NC score	0.030627 (rank : 71)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C5W4, Q8CG24	Gene names	Morc2b, Tce6
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2B (TCE6).

MO4L1_HUMAN
NC score	0.030554 (rank : 72)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

ARRD1_HUMAN
NC score	0.030443 (rank : 73)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

CD44_MOUSE
NC score	0.030163 (rank : 74)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	P15379, Q05732, Q61395, Q62060, Q62061, Q62062, Q62063, Q62408, Q62409, Q64296, Q99J14, Q9QYX8	Gene names	Cd44, Ly-24
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein 1) (PGP-1) (HUTCH-I) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen Ly-24).

HGS_HUMAN
NC score	0.029800 (rank : 75)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	517	Shared Neighborhood Hits	32
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

LAD1_MOUSE
NC score	0.029652 (rank : 76)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	391	Shared Neighborhood Hits	23
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

DIDO1_HUMAN
NC score	0.029135 (rank : 77)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	960	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SYNG_HUMAN
NC score	0.028527 (rank : 78)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	160	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

NFAT5_HUMAN
NC score	0.028047 (rank : 79)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	217	Shared Neighborhood Hits	18
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

RFX1_HUMAN
NC score	0.025271 (rank : 80)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	256	Shared Neighborhood Hits	22
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

PCNT_MOUSE
NC score	0.024752 (rank : 81)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	1207	Shared Neighborhood Hits	26
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

UBP37_HUMAN
NC score	0.024726 (rank : 82)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	9
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

MO4L1_MOUSE
NC score	0.024672 (rank : 83)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

GGA1_MOUSE
NC score	0.023899 (rank : 84)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

SRBS1_MOUSE
NC score	0.023809 (rank : 85)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PDZD2_HUMAN
NC score	0.023236 (rank : 86)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	772	Shared Neighborhood Hits	26
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

ATBF1_HUMAN
NC score	0.023213 (rank : 87)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	1547	Shared Neighborhood Hits	38
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATBF1_MOUSE
NC score	0.022349 (rank : 88)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	1841	Shared Neighborhood Hits	44
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

GOGA4_MOUSE
NC score	0.022247 (rank : 89)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	1939	Shared Neighborhood Hits	44
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

FETUB_MOUSE
NC score	0.022201 (rank : 90)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

TAU_HUMAN
NC score	0.021878 (rank : 91)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	448	Shared Neighborhood Hits	25
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

WNK1_HUMAN
NC score	0.021580 (rank : 92)	θ value	0.00102713 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	1158	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

EP400_HUMAN
NC score	0.021495 (rank : 93)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

OFD1_HUMAN
NC score	0.021017 (rank : 94)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	753	Shared Neighborhood Hits	21
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

RYR2_HUMAN
NC score	0.020946 (rank : 95)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

TTC3_HUMAN
NC score	0.020892 (rank : 96)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	664	Shared Neighborhood Hits	20
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

OXR1_HUMAN
NC score	0.020662 (rank : 97)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	282	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

MUC5B_HUMAN
NC score	0.019624 (rank : 98)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	1020	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NEDD1_HUMAN
NC score	0.019317 (rank : 99)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	294	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

KCNH6_HUMAN
NC score	0.018864 (rank : 100)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

CN145_HUMAN
NC score	0.018737 (rank : 101)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	1196	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CCD21_MOUSE
NC score	0.018357 (rank : 102)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

AFF4_MOUSE
NC score	0.018225 (rank : 103)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CN092_MOUSE
NC score	0.017651 (rank : 104)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

WNK1_MOUSE
NC score	0.017387 (rank : 105)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	1179	Shared Neighborhood Hits	29
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

IREB2_HUMAN
NC score	0.016742 (rank : 106)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P48200, Q13095	Gene names	IREB2
Domain Architecture
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

CNGB1_HUMAN
NC score	0.016505 (rank : 107)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	222	Shared Neighborhood Hits	17
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

SOX9_MOUSE
NC score	0.016487 (rank : 108)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

PREP_MOUSE
NC score	0.016407 (rank : 109)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K411, Q3THC4, Q3TJI1, Q3TPP0, Q3URQ8, Q4KUG2, Q4KUG3, Q6ZPX6, Q922N1, Q9CV63	Gene names	Pitrm1, Kiaa1104, Ntup1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (Pitrilysin metalloproteinase 1).

CN092_HUMAN
NC score	0.016364 (rank : 110)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	143	Shared Neighborhood Hits	12
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

UBQL2_MOUSE
NC score	0.015856 (rank : 111)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

EAF1_HUMAN
NC score	0.015311 (rank : 112)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

CM007_HUMAN
NC score	0.014946 (rank : 113)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	422	Shared Neighborhood Hits	10
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TEF_HUMAN
NC score	0.014775 (rank : 114)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q10587, Q15729, Q7Z3J7, Q8IU94, Q96TG4	Gene names	TEF
Domain Architecture
Description	Thyrotroph embryonic factor.

FA5_HUMAN
NC score	0.014226 (rank : 115)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

IREB2_MOUSE
NC score	0.014094 (rank : 116)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q811J3, O70235	Gene names	Ireb2, Irp2
Domain Architecture	No domain graphic available
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

CAR10_HUMAN
NC score	0.014064 (rank : 117)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	569	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

ASPP2_HUMAN
NC score	0.013957 (rank : 118)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	1156	Shared Neighborhood Hits	40
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

SOX9_HUMAN
NC score	0.013566 (rank : 119)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	210	Shared Neighborhood Hits	13
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

FOXJ2_HUMAN
NC score	0.013371 (rank : 120)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	239	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

FOXJ3_MOUSE
NC score	0.013292 (rank : 121)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	190	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

XRN1_HUMAN
NC score	0.012830 (rank : 122)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

K1267_HUMAN
NC score	0.012150 (rank : 123)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

CASP_HUMAN
NC score	0.011712 (rank : 124)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	1131	Shared Neighborhood Hits	29
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

SASH1_HUMAN
NC score	0.011431 (rank : 125)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	292	Shared Neighborhood Hits	12
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

CU013_HUMAN
NC score	0.011411 (rank : 126)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	405	Shared Neighborhood Hits	11
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

EPAS1_HUMAN
NC score	0.011391 (rank : 127)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

ELK1_HUMAN
NC score	0.011288 (rank : 128)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

RNF8_MOUSE
NC score	0.011273 (rank : 129)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	618	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

ZEP2_HUMAN
NC score	0.010684 (rank : 130)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	937	Shared Neighborhood Hits	20
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

STABP_MOUSE
NC score	0.010577 (rank : 131)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	191	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

ZN438_HUMAN
NC score	0.010344 (rank : 132)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

TTLL4_MOUSE
NC score	0.010293 (rank : 133)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

LUZP1_MOUSE
NC score	0.010282 (rank : 134)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	940	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

EEA1_MOUSE
NC score	0.009988 (rank : 135)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	1637	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

LRC45_MOUSE
NC score	0.009869 (rank : 136)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	959	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

PMS2_HUMAN
NC score	0.009502 (rank : 137)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

KBTBB_MOUSE
NC score	0.009342 (rank : 138)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	184	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BNW9	Gene names	Kbtbd11, Kiaa0711
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 11.

TRI56_MOUSE
NC score	0.008103 (rank : 139)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	255	Shared Neighborhood Hits	8
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI46_HUMAN
NC score	0.007922 (rank : 140)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	291	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

SI1L1_MOUSE
NC score	0.007857 (rank : 141)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

BRDT_MOUSE
NC score	0.007657 (rank : 142)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

PPE2_HUMAN
NC score	0.007241 (rank : 143)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O14830, O14831	Gene names	PPEF2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

NR4A3_MOUSE
NC score	0.007168 (rank : 144)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NOTC1_HUMAN
NC score	0.006167 (rank : 145)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SEPT4_MOUSE
NC score	0.006142 (rank : 146)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	P28661, Q5ND15	Gene names	Sept4, Pnutl2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5).

PCSK7_MOUSE
NC score	0.005278 (rank : 147)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

BMP2K_MOUSE
NC score	0.004709 (rank : 148)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

FNDC3_MOUSE
NC score	0.003953 (rank : 149)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

M4K4_HUMAN
NC score	0.003805 (rank : 150)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	1589	Shared Neighborhood Hits	29
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

EVI1_HUMAN
NC score	0.003073 (rank : 151)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	924	Shared Neighborhood Hits	13
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

ZN335_HUMAN
NC score	0.000081 (rank : 152)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	973	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.