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Network neighborhood for query Sequence : IREB2_HUMAN

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IREB2_HUMAN
SwissProt Accessions	P48200, Q13095	Gene names	IREB2
Domain Architecture
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IREB1_HUMAN
θ value	0 (rank : 1)	NC score	0.988347 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P21399, Q14652	Gene names	ACO1, IREB1
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

IREB1_MOUSE
θ value	0 (rank : 2)	NC score	0.988029 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	P28271, Q99K54	Gene names	Aco1, Ireb1, Irebp
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

IREB2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P48200, Q13095	Gene names	IREB2
Domain Architecture
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

IREB2_MOUSE
θ value	0 (rank : 4)	NC score	0.999544 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q811J3, O70235	Gene names	Ireb2, Irp2
Domain Architecture	No domain graphic available
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

ACON_MOUSE
θ value	9.83387e-39 (rank : 5)	NC score	0.766384 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KI0	Gene names	Aco2
Domain Architecture	No domain graphic available
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

ACON_HUMAN
θ value	4.88048e-38 (rank : 6)	NC score	0.765874 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q99798, O75809	Gene names	ACO2
Domain Architecture
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

BAF_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.046870 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	O54962, Q542E6	Gene names	Banf1, Baf, Bcrp1, L2bp1
Domain Architecture
Description	Barrier-to-autointegration factor (Breakpoint cluster region protein 1) (LAP2-binding protein 1).

DIAP3_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.011648 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	221	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

MYCD_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.016742 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

DUS16_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.007379 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

Hits sorted by NC score

IREB2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P48200, Q13095	Gene names	IREB2
Domain Architecture
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

IREB2_MOUSE
NC score	0.999544 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q811J3, O70235	Gene names	Ireb2, Irp2
Domain Architecture	No domain graphic available
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

IREB1_HUMAN
NC score	0.988347 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P21399, Q14652	Gene names	ACO1, IREB1
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

IREB1_MOUSE
NC score	0.988029 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	P28271, Q99K54	Gene names	Aco1, Ireb1, Irebp
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

ACON_MOUSE
NC score	0.766384 (rank : 5)	θ value	9.83387e-39 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KI0	Gene names	Aco2
Domain Architecture	No domain graphic available
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

ACON_HUMAN
NC score	0.765874 (rank : 6)	θ value	4.88048e-38 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q99798, O75809	Gene names	ACO2
Domain Architecture
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

BAF_MOUSE
NC score	0.046870 (rank : 7)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	O54962, Q542E6	Gene names	Banf1, Baf, Bcrp1, L2bp1
Domain Architecture
Description	Barrier-to-autointegration factor (Breakpoint cluster region protein 1) (LAP2-binding protein 1).

MYCD_MOUSE
NC score	0.016742 (rank : 8)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

DIAP3_MOUSE
NC score	0.011648 (rank : 9)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	221	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DUS16_HUMAN
NC score	0.007379 (rank : 10)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).