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Network neighborhood for query Sequence : RYR2_HUMAN

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RYR2_HUMAN
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RYR1_HUMAN
θ value	0 (rank : 1)	NC score	0.960515 (rank : 3)
Query Neighborhood Hits	175	Target Neighborhood Hits	303	Shared Neighborhood Hits	42
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

RYR2_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	175	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

RYR3_HUMAN
θ value	0 (rank : 3)	NC score	0.975845 (rank : 2)
Query Neighborhood Hits	175	Target Neighborhood Hits	134	Shared Neighborhood Hits	53
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

ITPR1_HUMAN
θ value	2.50655e-34 (rank : 4)	NC score	0.551793 (rank : 4)
Query Neighborhood Hits	175	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
θ value	3.61944e-33 (rank : 5)	NC score	0.547645 (rank : 5)
Query Neighborhood Hits	175	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

ITPR3_MOUSE
θ value	4.14116e-29 (rank : 6)	NC score	0.536082 (rank : 6)
Query Neighborhood Hits	175	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR3_HUMAN
θ value	3.50572e-28 (rank : 7)	NC score	0.532386 (rank : 7)
Query Neighborhood Hits	175	Target Neighborhood Hits	114	Shared Neighborhood Hits	15
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR2_MOUSE
θ value	8.63488e-27 (rank : 8)	NC score	0.530770 (rank : 8)
Query Neighborhood Hits	175	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

ITPR2_HUMAN
θ value	1.12775e-26 (rank : 9)	NC score	0.530373 (rank : 9)
Query Neighborhood Hits	175	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

RN123_HUMAN
θ value	1.16975e-15 (rank : 10)	NC score	0.385322 (rank : 10)
Query Neighborhood Hits	175	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	1.16975e-15 (rank : 11)	NC score	0.384725 (rank : 11)
Query Neighborhood Hits	175	Target Neighborhood Hits	174	Shared Neighborhood Hits	15
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

DDX1_HUMAN
θ value	1.53129e-07 (rank : 12)	NC score	0.134068 (rank : 18)
Query Neighborhood Hits	175	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	2.61198e-07 (rank : 13)	NC score	0.131565 (rank : 19)
Query Neighborhood Hits	175	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

ASH2L_HUMAN
θ value	1.09739e-05 (rank : 14)	NC score	0.268550 (rank : 12)
Query Neighborhood Hits	175	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ASH2L_MOUSE
θ value	1.09739e-05 (rank : 15)	NC score	0.267962 (rank : 13)
Query Neighborhood Hits	175	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

RANB9_HUMAN
θ value	0.000158464 (rank : 16)	NC score	0.229152 (rank : 15)
Query Neighborhood Hits	175	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RANB9_MOUSE
θ value	0.000158464 (rank : 17)	NC score	0.242435 (rank : 14)
Query Neighborhood Hits	175	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	P69566	Gene names	Ranbp9, Ranbpm
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (Ran-binding protein M) (RanBPM) (B cell antigen receptor Ig beta-associated protein 1) (IBAP-1).

HNRL1_HUMAN
θ value	0.000786445 (rank : 18)	NC score	0.153746 (rank : 16)
Query Neighborhood Hits	175	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
θ value	0.000786445 (rank : 19)	NC score	0.153470 (rank : 17)
Query Neighborhood Hits	175	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

CABP5_HUMAN
θ value	0.0148317 (rank : 20)	NC score	0.096737 (rank : 21)
Query Neighborhood Hits	175	Target Neighborhood Hits	197	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

MYPT1_HUMAN
θ value	0.0193708 (rank : 21)	NC score	0.024030 (rank : 101)
Query Neighborhood Hits	175	Target Neighborhood Hits	723	Shared Neighborhood Hits	28
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

NKTR_MOUSE
θ value	0.0193708 (rank : 22)	NC score	0.027944 (rank : 95)
Query Neighborhood Hits	175	Target Neighborhood Hits	417	Shared Neighborhood Hits	14
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

CABP7_HUMAN
θ value	0.0330416 (rank : 23)	NC score	0.096707 (rank : 22)
Query Neighborhood Hits	175	Target Neighborhood Hits	205	Shared Neighborhood Hits	40
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
θ value	0.0330416 (rank : 24)	NC score	0.096707 (rank : 23)
Query Neighborhood Hits	175	Target Neighborhood Hits	205	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP3_HUMAN
θ value	0.0431538 (rank : 25)	NC score	0.100066 (rank : 20)
Query Neighborhood Hits	175	Target Neighborhood Hits	162	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CABP5_MOUSE
θ value	0.0736092 (rank : 26)	NC score	0.092515 (rank : 25)
Query Neighborhood Hits	175	Target Neighborhood Hits	207	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CALM_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.087480 (rank : 30)
Query Neighborhood Hits	175	Target Neighborhood Hits	232	Shared Neighborhood Hits	48
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.087480 (rank : 31)
Query Neighborhood Hits	175	Target Neighborhood Hits	232	Shared Neighborhood Hits	48
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

TRIM9_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.051346 (rank : 70)
Query Neighborhood Hits	175	Target Neighborhood Hits	294	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

ADA30_HUMAN
θ value	0.0961366 (rank : 30)	NC score	0.015382 (rank : 133)
Query Neighborhood Hits	175	Target Neighborhood Hits	391	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CALL3_HUMAN
θ value	0.0961366 (rank : 31)	NC score	0.085742 (rank : 32)
Query Neighborhood Hits	175	Target Neighborhood Hits	225	Shared Neighborhood Hits	46
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

MLRV_HUMAN
θ value	0.0961366 (rank : 32)	NC score	0.090892 (rank : 27)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	33
SwissProt Accessions	P10916, Q16123	Gene names	MYL2
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

TRIM9_MOUSE
θ value	0.0961366 (rank : 33)	NC score	0.051425 (rank : 69)
Query Neighborhood Hits	175	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

MPP8_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.025141 (rank : 99)
Query Neighborhood Hits	175	Target Neighborhood Hits	948	Shared Neighborhood Hits	32
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

DJBP_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.065157 (rank : 49)
Query Neighborhood Hits	175	Target Neighborhood Hits	152	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

GOGB1_HUMAN
θ value	0.163984 (rank : 36)	NC score	0.017276 (rank : 128)
Query Neighborhood Hits	175	Target Neighborhood Hits	2297	Shared Neighborhood Hits	49
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IWS1_MOUSE
θ value	0.21417 (rank : 37)	NC score	0.045687 (rank : 77)
Query Neighborhood Hits	175	Target Neighborhood Hits	1258	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MLR5_HUMAN
θ value	0.21417 (rank : 38)	NC score	0.090993 (rank : 26)
Query Neighborhood Hits	175	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q02045	Gene names	MYL5
Domain Architecture
Description	Superfast myosin regulatory light chain 2 (MyLC-2) (MYLC2) (Myosin regulatory light chain 5).

CALL6_HUMAN
θ value	0.279714 (rank : 39)	NC score	0.079802 (rank : 38)
Query Neighborhood Hits	175	Target Neighborhood Hits	157	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

RHBD4_HUMAN
θ value	0.279714 (rank : 40)	NC score	0.053511 (rank : 65)
Query Neighborhood Hits	175	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	P58872	Gene names	RHBDL4, VRHO
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

CABP2_MOUSE
θ value	0.365318 (rank : 41)	NC score	0.088388 (rank : 28)
Query Neighborhood Hits	175	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

MLRS_MOUSE
θ value	0.365318 (rank : 42)	NC score	0.081986 (rank : 36)
Query Neighborhood Hits	175	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	P97457	Gene names	Mylpf
Domain Architecture
Description	Myosin regulatory light chain 2, skeletal muscle isoform (MLC2F).

RHBD4_MOUSE
θ value	0.365318 (rank : 43)	NC score	0.052322 (rank : 67)
Query Neighborhood Hits	175	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	P58873	Gene names	Rhbdl4, Vrho
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

SDF2_HUMAN
θ value	0.365318 (rank : 44)	NC score	0.051064 (rank : 71)
Query Neighborhood Hits	175	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q99470, Q9BQ79	Gene names	SDF2
Domain Architecture
Description	Stromal cell-derived factor 2 precursor (SDF-2).

CABP2_HUMAN
θ value	0.47712 (rank : 45)	NC score	0.087669 (rank : 29)
Query Neighborhood Hits	175	Target Neighborhood Hits	205	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CAN2_MOUSE
θ value	0.47712 (rank : 46)	NC score	0.021960 (rank : 106)
Query Neighborhood Hits	175	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

PCAT1_HUMAN
θ value	0.47712 (rank : 47)	NC score	0.025103 (rank : 100)
Query Neighborhood Hits	175	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NF37, Q1HAQ1, Q7Z4G6, Q8N3U7, Q8WUL8, Q9GZW6	Gene names	AYTL2, LPCAT1, PFAAP3
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3).

UBP47_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.023286 (rank : 102)
Query Neighborhood Hits	175	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

MEP50_MOUSE
θ value	0.62314 (rank : 49)	NC score	0.017886 (rank : 123)
Query Neighborhood Hits	175	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

MLRV_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.082663 (rank : 34)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	P51667	Gene names	Myl2, Mylpc
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

MYPT1_MOUSE
θ value	0.62314 (rank : 51)	NC score	0.019121 (rank : 117)
Query Neighborhood Hits	175	Target Neighborhood Hits	539	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

SDF2_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.048861 (rank : 75)
Query Neighborhood Hits	175	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCT5, P97307	Gene names	Sdf2
Domain Architecture
Description	Stromal cell-derived factor 2 precursor (SDF-2).

SOMA_HUMAN
θ value	0.813845 (rank : 53)	NC score	0.041995 (rank : 79)
Query Neighborhood Hits	175	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	P01241, Q14405, Q16631, Q5EB53, Q9HBZ1, Q9UMJ7, Q9UNL5	Gene names	GH1
Domain Architecture
Description	Somatotropin precursor (Growth hormone) (GH) (GH-N) (Pituitary growth hormone) (Growth hormone 1).

SPTN4_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.016581 (rank : 130)
Query Neighborhood Hits	175	Target Neighborhood Hits	570	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

UBP47_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.022298 (rank : 104)
Query Neighborhood Hits	175	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

ZCPW1_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.028517 (rank : 94)
Query Neighborhood Hits	175	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

CABP1_MOUSE
θ value	1.06291 (rank : 57)	NC score	0.079602 (rank : 40)
Query Neighborhood Hits	175	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CH60_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.021791 (rank : 107)
Query Neighborhood Hits	175	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

CP135_MOUSE
θ value	1.06291 (rank : 59)	NC score	0.010609 (rank : 153)
Query Neighborhood Hits	175	Target Neighborhood Hits	1278	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

SESN2_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.017594 (rank : 127)
Query Neighborhood Hits	175	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

SMC4_HUMAN
θ value	1.06291 (rank : 61)	NC score	0.013683 (rank : 139)
Query Neighborhood Hits	175	Target Neighborhood Hits	937	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SMRCD_MOUSE
θ value	1.06291 (rank : 62)	NC score	0.009881 (rank : 158)
Query Neighborhood Hits	175	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

XRCC4_HUMAN
θ value	1.06291 (rank : 63)	NC score	0.031893 (rank : 91)
Query Neighborhood Hits	175	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

CABP1_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.078916 (rank : 43)
Query Neighborhood Hits	175	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CALL5_HUMAN
θ value	1.38821 (rank : 65)	NC score	0.085319 (rank : 33)
Query Neighborhood Hits	175	Target Neighborhood Hits	231	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

LETM1_HUMAN
θ value	1.38821 (rank : 66)	NC score	0.026238 (rank : 96)
Query Neighborhood Hits	175	Target Neighborhood Hits	338	Shared Neighborhood Hits	18
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

MATR3_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.054857 (rank : 64)
Query Neighborhood Hits	175	Target Neighborhood Hits	325	Shared Neighborhood Hits	12
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MATR3_MOUSE
θ value	1.38821 (rank : 68)	NC score	0.061785 (rank : 54)
Query Neighborhood Hits	175	Target Neighborhood Hits	321	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MLRA_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.082496 (rank : 35)
Query Neighborhood Hits	175	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QVP4, Q63977, Q9JIE8	Gene names	Myl7, Mylc2a
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

MYL3_MOUSE
θ value	1.38821 (rank : 70)	NC score	0.055679 (rank : 61)
Query Neighborhood Hits	175	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P09542, Q3UIF4, Q9CQZ2	Gene names	Myl3, Mlc1v, Mylc
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain).

MYST3_HUMAN
θ value	1.38821 (rank : 71)	NC score	0.021969 (rank : 105)
Query Neighborhood Hits	175	Target Neighborhood Hits	772	Shared Neighborhood Hits	20
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NEB2_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.017603 (rank : 126)
Query Neighborhood Hits	175	Target Neighborhood Hits	883	Shared Neighborhood Hits	22
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PLSL_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.039336 (rank : 83)
Query Neighborhood Hits	175	Target Neighborhood Hits	168	Shared Neighborhood Hits	32
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

PLSL_MOUSE
θ value	1.38821 (rank : 74)	NC score	0.039428 (rank : 82)
Query Neighborhood Hits	175	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

POGK_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.010631 (rank : 152)
Query Neighborhood Hits	175	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TC5, Q8BPJ3, Q8C887	Gene names	Pogk, Kiaa1513
Domain Architecture
Description	Pogo transposable element with KRAB domain.

SDF2L_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.043488 (rank : 78)
Query Neighborhood Hits	175	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESP1, Q9ESP2	Gene names	Sdf2l1
Domain Architecture
Description	Stromal cell-derived factor 2-like protein 1 precursor (SDF2-like protein 1).

ST17A_HUMAN
θ value	1.38821 (rank : 77)	NC score	-0.000939 (rank : 188)
Query Neighborhood Hits	175	Target Neighborhood Hits	843	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UEE5, Q8IVC8	Gene names	STK17A, DRAK1
Domain Architecture
Description	Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1).

TBCD1_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.017211 (rank : 129)
Query Neighborhood Hits	175	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

CALN1_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.079467 (rank : 42)
Query Neighborhood Hits	175	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
θ value	1.81305 (rank : 80)	NC score	0.079511 (rank : 41)
Query Neighborhood Hits	175	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

CAN2_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.019671 (rank : 114)
Query Neighborhood Hits	175	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CLSPN_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.021781 (rank : 108)
Query Neighborhood Hits	175	Target Neighborhood Hits	433	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

DJBP_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.073451 (rank : 46)
Query Neighborhood Hits	175	Target Neighborhood Hits	156	Shared Neighborhood Hits	34
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

DOCK1_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.010551 (rank : 154)
Query Neighborhood Hits	175	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

IQGA1_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.014603 (rank : 137)
Query Neighborhood Hits	175	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

MLRA_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.080998 (rank : 37)
Query Neighborhood Hits	175	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q01449	Gene names	MYL7, MYLC2A
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

MYL3_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.053387 (rank : 66)
Query Neighborhood Hits	175	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	P08590, Q9NRS8	Gene names	MYL3
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain) (Cardiac myosin light chain-1) (CMLC1).

PRP40_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.031151 (rank : 92)
Query Neighborhood Hits	175	Target Neighborhood Hits	442	Shared Neighborhood Hits	20
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

CD33_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.012149 (rank : 147)
Query Neighborhood Hits	175	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q63994, Q63997	Gene names	Cd33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3).

HMGN1_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.039154 (rank : 84)
Query Neighborhood Hits	175	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P05114, Q3KQR8	Gene names	HMGN1, HMG14
Domain Architecture	No domain graphic available
Description	Nonhistone chromosomal protein HMG-14 (High-mobility group nucleosome- binding domain-containing protein 1).

PPE1_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.021011 (rank : 110)
Query Neighborhood Hits	175	Target Neighborhood Hits	137	Shared Neighborhood Hits	23
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

TRPC4_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.017735 (rank : 124)
Query Neighborhood Hits	175	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.017676 (rank : 125)
Query Neighborhood Hits	175	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC6_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.018054 (rank : 120)
Query Neighborhood Hits	175	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

CAN3_MOUSE
θ value	3.0926 (rank : 95)	NC score	0.021460 (rank : 109)
Query Neighborhood Hits	175	Target Neighborhood Hits	115	Shared Neighborhood Hits	22
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

EFHB_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.041430 (rank : 80)
Query Neighborhood Hits	175	Target Neighborhood Hits	120	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

EGLX_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.033756 (rank : 88)
Query Neighborhood Hits	175	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NXG6, Q6PAG6, Q8TCJ9, Q8WV55, Q96F22, Q9BW77	Gene names	PH4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

EGLX_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.032144 (rank : 90)
Query Neighborhood Hits	175	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BG58, Q8CAF1, Q9D499	Gene names	Ph4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

MYCD_MOUSE
θ value	3.0926 (rank : 99)	NC score	0.020946 (rank : 111)
Query Neighborhood Hits	175	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

NEB2_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.015193 (rank : 135)
Query Neighborhood Hits	175	Target Neighborhood Hits	889	Shared Neighborhood Hits	21
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NIBA_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.017905 (rank : 122)
Query Neighborhood Hits	175	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

POT14_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.012473 (rank : 146)
Query Neighborhood Hits	175	Target Neighborhood Hits	403	Shared Neighborhood Hits	16
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

SUHW4_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.003032 (rank : 183)
Query Neighborhood Hits	175	Target Neighborhood Hits	860	Shared Neighborhood Hits	15
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

AIF1_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.036336 (rank : 86)
Query Neighborhood Hits	175	Target Neighborhood Hits	44	Shared Neighborhood Hits	19
SwissProt Accessions	P55008, Q9UKS9	Gene names	AIF1, G1, IBA1
Domain Architecture
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1).

CPNS2_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.023089 (rank : 103)
Query Neighborhood Hits	175	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

FIGN_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.006728 (rank : 172)
Query Neighborhood Hits	175	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

LIMK2_HUMAN
θ value	4.03905 (rank : 107)	NC score	-0.000714 (rank : 187)
Query Neighborhood Hits	175	Target Neighborhood Hits	986	Shared Neighborhood Hits	7
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

MYCD_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.019136 (rank : 116)
Query Neighborhood Hits	175	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

ONCO_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.050876 (rank : 72)
Query Neighborhood Hits	175	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

RRP5_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.019298 (rank : 115)
Query Neighborhood Hits	175	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

SDF2L_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.037981 (rank : 85)
Query Neighborhood Hits	175	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCN8, Q9BRI5	Gene names	SDF2L1
Domain Architecture
Description	Stromal cell-derived factor 2-like protein 1 precursor (SDF2-like protein 1) (PWP1-interacting protein 8).

TEX14_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.006942 (rank : 169)
Query Neighborhood Hits	175	Target Neighborhood Hits	1103	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

UNC5B_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.013662 (rank : 141)
Query Neighborhood Hits	175	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

WDR7_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.010365 (rank : 156)
Query Neighborhood Hits	175	Target Neighborhood Hits	244	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

ASM_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.011215 (rank : 149)
Query Neighborhood Hits	175	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P17405, P17406, Q13811, Q16837, Q16841	Gene names	SMPD1, ASM
Domain Architecture
Description	Sphingomyelin phosphodiesterase precursor (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase).

CAYP2_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.035376 (rank : 87)
Query Neighborhood Hits	175	Target Neighborhood Hits	98	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

EEA1_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.007438 (rank : 168)
Query Neighborhood Hits	175	Target Neighborhood Hits	1637	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

IWS1_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.029616 (rank : 93)
Query Neighborhood Hits	175	Target Neighborhood Hits	1241	Shared Neighborhood Hits	32
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYH10_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.005895 (rank : 178)
Query Neighborhood Hits	175	Target Neighborhood Hits	1620	Shared Neighborhood Hits	33
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.006768 (rank : 171)
Query Neighborhood Hits	175	Target Neighborhood Hits	1612	Shared Neighborhood Hits	36
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

N4BP2_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.017959 (rank : 121)
Query Neighborhood Hits	175	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

POK7_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.005199 (rank : 181)
Query Neighborhood Hits	175	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

RIMS1_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.006841 (rank : 170)
Query Neighborhood Hits	175	Target Neighborhood Hits	437	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SC11A_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.010951 (rank : 150)
Query Neighborhood Hits	175	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SFRIP_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.018307 (rank : 119)
Query Neighborhood Hits	175	Target Neighborhood Hits	530	Shared Neighborhood Hits	13
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

TNNC2_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.063876 (rank : 53)
Query Neighborhood Hits	175	Target Neighborhood Hits	234	Shared Neighborhood Hits	50
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

TNNC2_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.064151 (rank : 51)
Query Neighborhood Hits	175	Target Neighborhood Hits	233	Shared Neighborhood Hits	49
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

TRPC6_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.016267 (rank : 131)
Query Neighborhood Hits	175	Target Neighborhood Hits	171	Shared Neighborhood Hits	9
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

UNC5B_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.013668 (rank : 140)
Query Neighborhood Hits	175	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

ZN366_HUMAN
θ value	5.27518 (rank : 130)	NC score	-0.002145 (rank : 190)
Query Neighborhood Hits	175	Target Neighborhood Hits	732	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.

ZN586_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.000266 (rank : 185)
Query Neighborhood Hits	175	Target Neighborhood Hits	637	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NXT0	Gene names	ZNF586
Domain Architecture	No domain graphic available
Description	Zinc finger protein 586.

ANKR5_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.009611 (rank : 159)
Query Neighborhood Hits	175	Target Neighborhood Hits	298	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ATX2_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.006706 (rank : 173)
Query Neighborhood Hits	175	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CAN3_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.019782 (rank : 112)
Query Neighborhood Hits	175	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CCD38_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.012569 (rank : 145)
Query Neighborhood Hits	175	Target Neighborhood Hits	287	Shared Neighborhood Hits	14
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CENPF_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.009036 (rank : 161)
Query Neighborhood Hits	175	Target Neighborhood Hits	1932	Shared Neighborhood Hits	43
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CND3_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.045830 (rank : 76)
Query Neighborhood Hits	175	Target Neighborhood Hits	74	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BPX3, Q96SV9, Q9BUR3, Q9BVY1, Q9H914, Q9H9Z6, Q9HBI9	Gene names	NCAPG, CAPG, NYMEL3
Domain Architecture
Description	Condensin complex subunit 3 (Non-SMC condensin I complex subunit G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (XCAP-G homolog) (Antigen NY-MEL-3).

CSH_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.015976 (rank : 132)
Query Neighborhood Hits	175	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P01243, Q14407	Gene names	CSH1
Domain Architecture
Description	Chorionic somatomammotropin hormone precursor (Choriomammotropin) (Lactogen).

DNMT1_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.012821 (rank : 144)
Query Neighborhood Hits	175	Target Neighborhood Hits	401	Shared Neighborhood Hits	16
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

SNW1_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.011217 (rank : 148)
Query Neighborhood Hits	175	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

SPRY4_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.040663 (rank : 81)
Query Neighborhood Hits	175	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TYRO_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.007958 (rank : 164)
Query Neighborhood Hits	175	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

ZFP59_MOUSE
θ value	6.88961 (rank : 143)	NC score	-0.001708 (rank : 189)
Query Neighborhood Hits	175	Target Neighborhood Hits	768	Shared Neighborhood Hits	7
SwissProt Accessions	P16373, Q61849	Gene names	Zfp59, Mfg2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 59 (Zfp-59) (Zinc finger protein Mfg-2).

ARHG3_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.005859 (rank : 179)
Query Neighborhood Hits	175	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.005856 (rank : 180)
Query Neighborhood Hits	175	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

BCOR_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.007721 (rank : 166)
Query Neighborhood Hits	175	Target Neighborhood Hits	609	Shared Neighborhood Hits	16
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BSH_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.000204 (rank : 186)
Query Neighborhood Hits	175	Target Neighborhood Hits	349	Shared Neighborhood Hits	2
SwissProt Accessions	Q810B3	Gene names	Bsx
Domain Architecture	No domain graphic available
Description	Brain-specific homeobox protein homolog.

CALM4_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.065467 (rank : 48)
Query Neighborhood Hits	175	Target Neighborhood Hits	229	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CEP72_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.010483 (rank : 155)
Query Neighborhood Hits	175	Target Neighborhood Hits	374	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CJ118_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.014616 (rank : 136)
Query Neighborhood Hits	175	Target Neighborhood Hits	1132	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CYLN2_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.006412 (rank : 174)
Query Neighborhood Hits	175	Target Neighborhood Hits	1004	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

DPOD4_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.015336 (rank : 134)
Query Neighborhood Hits	175	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CWP8	Gene names	Pold4
Domain Architecture
Description	DNA polymerase subunit delta 4 (DNA polymerase subunit delta p12).

EP15R_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.008361 (rank : 163)
Query Neighborhood Hits	175	Target Neighborhood Hits	1135	Shared Neighborhood Hits	36
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EXOC8_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.009178 (rank : 160)
Query Neighborhood Hits	175	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYI6, Q5TE82	Gene names	EXOC8
Domain Architecture	No domain graphic available
Description	Exocyst complex component 8 (Exocyst complex 84 kDa subunit).

FAK2_MOUSE
θ value	8.99809 (rank : 155)	NC score	-0.002272 (rank : 192)
Query Neighborhood Hits	175	Target Neighborhood Hits	851	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

JHD3C_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.003896 (rank : 182)
Query Neighborhood Hits	175	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

LETM1_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.019695 (rank : 113)
Query Neighborhood Hits	175	Target Neighborhood Hits	240	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LYST_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.008578 (rank : 162)
Query Neighborhood Hits	175	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

MKL2_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.013324 (rank : 142)
Query Neighborhood Hits	175	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

MLE1_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.049632 (rank : 74)
Query Neighborhood Hits	175	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	P05976	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MYH11_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.006373 (rank : 175)
Query Neighborhood Hits	175	Target Neighborhood Hits	1806	Shared Neighborhood Hits	40
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYST3_MOUSE
θ value	8.99809 (rank : 162)	NC score	0.013284 (rank : 143)
Query Neighborhood Hits	175	Target Neighborhood Hits	688	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NASP_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.019057 (rank : 118)
Query Neighborhood Hits	175	Target Neighborhood Hits	709	Shared Neighborhood Hits	30
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCOR2_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.010924 (rank : 151)
Query Neighborhood Hits	175	Target Neighborhood Hits	790	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PTN13_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.001490 (rank : 184)
Query Neighborhood Hits	175	Target Neighborhood Hits	426	Shared Neighborhood Hits	6
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

RM40_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.033712 (rank : 89)
Query Neighborhood Hits	175	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2Q5, Q9CS52	Gene names	Mrpl40, Nlvcf
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L40, mitochondrial precursor (L40mt) (MRP-40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog).

TAF1_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.006222 (rank : 177)
Query Neighborhood Hits	175	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TRPC3_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.014386 (rank : 138)
Query Neighborhood Hits	175	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TXLNA_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.007803 (rank : 165)
Query Neighborhood Hits	175	Target Neighborhood Hits	846	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

UACA_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.006271 (rank : 176)
Query Neighborhood Hits	175	Target Neighborhood Hits	1620	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

UBCP1_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.026229 (rank : 97)
Query Neighborhood Hits	175	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVY7, Q96DK5	Gene names	UBLCP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16).

UBCP1_MOUSE
θ value	8.99809 (rank : 172)	NC score	0.026226 (rank : 98)
Query Neighborhood Hits	175	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGR9, Q52L62, Q5XJH1, Q6PH96, Q99LT3	Gene names	Ublcp1
Domain Architecture	No domain graphic available
Description	Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16).

UT14B_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.007592 (rank : 167)
Query Neighborhood Hits	175	Target Neighborhood Hits	226	Shared Neighborhood Hits	13
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

VATC_MOUSE
θ value	8.99809 (rank : 174)	NC score	0.010151 (rank : 157)
Query Neighborhood Hits	175	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1G3	Gene names	Atp6v1c1, Atp6c, Vatc
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

ZBT40_HUMAN
θ value	8.99809 (rank : 175)	NC score	-0.002221 (rank : 191)
Query Neighborhood Hits	175	Target Neighborhood Hits	949	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

CABP4_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.064902 (rank : 50)
Query Neighborhood Hits	175	Target Neighborhood Hits	250	Shared Neighborhood Hits	39
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CABP4_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.063878 (rank : 52)
Query Neighborhood Hits	175	Target Neighborhood Hits	212	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CETN1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.057124 (rank : 57)
Query Neighborhood Hits	175	Target Neighborhood Hits	232	Shared Neighborhood Hits	48
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CETN1_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.056760 (rank : 58)
Query Neighborhood Hits	175	Target Neighborhood Hits	231	Shared Neighborhood Hits	45
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

CETN2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.057599 (rank : 55)
Query Neighborhood Hits	175	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN2_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.057569 (rank : 56)
Query Neighborhood Hits	175	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN3_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.055050 (rank : 62)
Query Neighborhood Hits	175	Target Neighborhood Hits	211	Shared Neighborhood Hits	41
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CETN3_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.054921 (rank : 63)
Query Neighborhood Hits	175	Target Neighborhood Hits	208	Shared Neighborhood Hits	40
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

EFCB2_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.070780 (rank : 47)
Query Neighborhood Hits	175	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CQ46, Q9CS07	Gene names	Efcab2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

HNRPU_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.095155 (rank : 24)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

MLRM_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.077341 (rank : 44)
Query Neighborhood Hits	175	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	P19105	Gene names	MRLC2, MLCB, RLC
Domain Architecture
Description	Myosin regulatory light chain 2, nonsarcomeric (Myosin RLC).

MLRN_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.076807 (rank : 45)
Query Neighborhood Hits	175	Target Neighborhood Hits	107	Shared Neighborhood Hits	33
SwissProt Accessions	P24844, Q9H136	Gene names	MYL9, MLC2, MRLC1, MYRL2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9) (LC20).

MLRN_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.079729 (rank : 39)
Query Neighborhood Hits	175	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CQ19, Q80X77	Gene names	Myl9, Myrl2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9).

MYL6B_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.051481 (rank : 68)
Query Neighborhood Hits	175	Target Neighborhood Hits	78	Shared Neighborhood Hits	32
SwissProt Accessions	P14649	Gene names	MYL6B, MLC1SA
Domain Architecture
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B) (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa).

SPRY3_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.050027 (rank : 73)
Query Neighborhood Hits	175	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NCJ5, Q96SK5	Gene names	SPRYD3
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 3.

TNNC1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.056382 (rank : 60)
Query Neighborhood Hits	175	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC1_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.056547 (rank : 59)
Query Neighborhood Hits	175	Target Neighborhood Hits	221	Shared Neighborhood Hits	46
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

Hits sorted by NC score

RYR2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	175	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

RYR3_HUMAN
NC score	0.975845 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	175	Target Neighborhood Hits	134	Shared Neighborhood Hits	53
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

RYR1_HUMAN
NC score	0.960515 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	175	Target Neighborhood Hits	303	Shared Neighborhood Hits	42
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

ITPR1_HUMAN
NC score	0.551793 (rank : 4)	θ value	2.50655e-34 (rank : 4)
Query Neighborhood Hits	175	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
NC score	0.547645 (rank : 5)	θ value	3.61944e-33 (rank : 5)
Query Neighborhood Hits	175	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

ITPR3_MOUSE
NC score	0.536082 (rank : 6)	θ value	4.14116e-29 (rank : 6)
Query Neighborhood Hits	175	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR3_HUMAN
NC score	0.532386 (rank : 7)	θ value	3.50572e-28 (rank : 7)
Query Neighborhood Hits	175	Target Neighborhood Hits	114	Shared Neighborhood Hits	15
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR2_MOUSE
NC score	0.530770 (rank : 8)	θ value	8.63488e-27 (rank : 8)
Query Neighborhood Hits	175	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

ITPR2_HUMAN
NC score	0.530373 (rank : 9)	θ value	1.12775e-26 (rank : 9)
Query Neighborhood Hits	175	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

RN123_HUMAN
NC score	0.385322 (rank : 10)	θ value	1.16975e-15 (rank : 10)
Query Neighborhood Hits	175	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
NC score	0.384725 (rank : 11)	θ value	1.16975e-15 (rank : 11)
Query Neighborhood Hits	175	Target Neighborhood Hits	174	Shared Neighborhood Hits	15
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

ASH2L_HUMAN
NC score	0.268550 (rank : 12)	θ value	1.09739e-05 (rank : 14)
Query Neighborhood Hits	175	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ASH2L_MOUSE
NC score	0.267962 (rank : 13)	θ value	1.09739e-05 (rank : 15)
Query Neighborhood Hits	175	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

RANB9_MOUSE
NC score	0.242435 (rank : 14)	θ value	0.000158464 (rank : 17)
Query Neighborhood Hits	175	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	P69566	Gene names	Ranbp9, Ranbpm
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (Ran-binding protein M) (RanBPM) (B cell antigen receptor Ig beta-associated protein 1) (IBAP-1).

RANB9_HUMAN
NC score	0.229152 (rank : 15)	θ value	0.000158464 (rank : 16)
Query Neighborhood Hits	175	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

HNRL1_HUMAN
NC score	0.153746 (rank : 16)	θ value	0.000786445 (rank : 18)
Query Neighborhood Hits	175	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
NC score	0.153470 (rank : 17)	θ value	0.000786445 (rank : 19)
Query Neighborhood Hits	175	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

DDX1_HUMAN
NC score	0.134068 (rank : 18)	θ value	1.53129e-07 (rank : 12)
Query Neighborhood Hits	175	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
NC score	0.131565 (rank : 19)	θ value	2.61198e-07 (rank : 13)
Query Neighborhood Hits	175	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

CABP3_HUMAN
NC score	0.100066 (rank : 20)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	175	Target Neighborhood Hits	162	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CABP5_HUMAN
NC score	0.096737 (rank : 21)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	175	Target Neighborhood Hits	197	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP7_HUMAN
NC score	0.096707 (rank : 22)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	175	Target Neighborhood Hits	205	Shared Neighborhood Hits	40
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
NC score	0.096707 (rank : 23)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	175	Target Neighborhood Hits	205	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

HNRPU_HUMAN
NC score	0.095155 (rank : 24)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

CABP5_MOUSE
NC score	0.092515 (rank : 25)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	175	Target Neighborhood Hits	207	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

MLR5_HUMAN
NC score	0.090993 (rank : 26)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	175	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q02045	Gene names	MYL5
Domain Architecture
Description	Superfast myosin regulatory light chain 2 (MyLC-2) (MYLC2) (Myosin regulatory light chain 5).

MLRV_HUMAN
NC score	0.090892 (rank : 27)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	33
SwissProt Accessions	P10916, Q16123	Gene names	MYL2
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

CABP2_MOUSE
NC score	0.088388 (rank : 28)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	175	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP2_HUMAN
NC score	0.087669 (rank : 29)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	175	Target Neighborhood Hits	205	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CALM_HUMAN
NC score	0.087480 (rank : 30)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	175	Target Neighborhood Hits	232	Shared Neighborhood Hits	48
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
NC score	0.087480 (rank : 31)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	175	Target Neighborhood Hits	232	Shared Neighborhood Hits	48
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CALL3_HUMAN
NC score	0.085742 (rank : 32)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	175	Target Neighborhood Hits	225	Shared Neighborhood Hits	46
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

CALL5_HUMAN
NC score	0.085319 (rank : 33)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	175	Target Neighborhood Hits	231	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

MLRV_MOUSE
NC score	0.082663 (rank : 34)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	P51667	Gene names	Myl2, Mylpc
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

MLRA_MOUSE
NC score	0.082496 (rank : 35)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	175	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QVP4, Q63977, Q9JIE8	Gene names	Myl7, Mylc2a
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

MLRS_MOUSE
NC score	0.081986 (rank : 36)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	175	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	P97457	Gene names	Mylpf
Domain Architecture
Description	Myosin regulatory light chain 2, skeletal muscle isoform (MLC2F).

MLRA_HUMAN
NC score	0.080998 (rank : 37)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	175	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q01449	Gene names	MYL7, MYLC2A
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

CALL6_HUMAN
NC score	0.079802 (rank : 38)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	175	Target Neighborhood Hits	157	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

MLRN_MOUSE
NC score	0.079729 (rank : 39)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	175	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CQ19, Q80X77	Gene names	Myl9, Myrl2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9).

CABP1_MOUSE
NC score	0.079602 (rank : 40)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	175	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CALN1_MOUSE
NC score	0.079511 (rank : 41)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	175	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

CALN1_HUMAN
NC score	0.079467 (rank : 42)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	175	Target Neighborhood Hits	161	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CABP1_HUMAN
NC score	0.078916 (rank : 43)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	175	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

MLRM_HUMAN
NC score	0.077341 (rank : 44)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	175	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	P19105	Gene names	MRLC2, MLCB, RLC
Domain Architecture
Description	Myosin regulatory light chain 2, nonsarcomeric (Myosin RLC).

MLRN_HUMAN
NC score	0.076807 (rank : 45)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	175	Target Neighborhood Hits	107	Shared Neighborhood Hits	33
SwissProt Accessions	P24844, Q9H136	Gene names	MYL9, MLC2, MRLC1, MYRL2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9) (LC20).

DJBP_HUMAN
NC score	0.073451 (rank : 46)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	175	Target Neighborhood Hits	156	Shared Neighborhood Hits	34
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

EFCB2_MOUSE
NC score	0.070780 (rank : 47)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	175	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CQ46, Q9CS07	Gene names	Efcab2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

CALM4_MOUSE
NC score	0.065467 (rank : 48)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	175	Target Neighborhood Hits	229	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

DJBP_MOUSE
NC score	0.065157 (rank : 49)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	175	Target Neighborhood Hits	152	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

CABP4_HUMAN
NC score	0.064902 (rank : 50)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	175	Target Neighborhood Hits	250	Shared Neighborhood Hits	39
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

TNNC2_MOUSE
NC score	0.064151 (rank : 51)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	175	Target Neighborhood Hits	233	Shared Neighborhood Hits	49
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

CABP4_MOUSE
NC score	0.063878 (rank : 52)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	175	Target Neighborhood Hits	212	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

TNNC2_HUMAN
NC score	0.063876 (rank : 53)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	175	Target Neighborhood Hits	234	Shared Neighborhood Hits	50
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

MATR3_MOUSE
NC score	0.061785 (rank : 54)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	175	Target Neighborhood Hits	321	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

CETN2_HUMAN
NC score	0.057599 (rank : 55)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	175	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN2_MOUSE
NC score	0.057569 (rank : 56)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	175	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN1_HUMAN
NC score	0.057124 (rank : 57)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	175	Target Neighborhood Hits	232	Shared Neighborhood Hits	48
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CETN1_MOUSE
NC score	0.056760 (rank : 58)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	175	Target Neighborhood Hits	231	Shared Neighborhood Hits	45
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

TNNC1_MOUSE
NC score	0.056547 (rank : 59)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	175	Target Neighborhood Hits	221	Shared Neighborhood Hits	46
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC1_HUMAN
NC score	0.056382 (rank : 60)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	175	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

MYL3_MOUSE
NC score	0.055679 (rank : 61)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	175	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P09542, Q3UIF4, Q9CQZ2	Gene names	Myl3, Mlc1v, Mylc
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain).

CETN3_HUMAN
NC score	0.055050 (rank : 62)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	175	Target Neighborhood Hits	211	Shared Neighborhood Hits	41
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CETN3_MOUSE
NC score	0.054921 (rank : 63)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	175	Target Neighborhood Hits	208	Shared Neighborhood Hits	40
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

MATR3_HUMAN
NC score	0.054857 (rank : 64)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	175	Target Neighborhood Hits	325	Shared Neighborhood Hits	12
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

RHBD4_HUMAN
NC score	0.053511 (rank : 65)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	175	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	P58872	Gene names	RHBDL4, VRHO
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

MYL3_HUMAN
NC score	0.053387 (rank : 66)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	175	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	P08590, Q9NRS8	Gene names	MYL3
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain) (Cardiac myosin light chain-1) (CMLC1).

RHBD4_MOUSE
NC score	0.052322 (rank : 67)	θ value	0.365318 (rank : 43)
Query Neighborhood Hits	175	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	P58873	Gene names	Rhbdl4, Vrho
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

MYL6B_HUMAN
NC score	0.051481 (rank : 68)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	175	Target Neighborhood Hits	78	Shared Neighborhood Hits	32
SwissProt Accessions	P14649	Gene names	MYL6B, MLC1SA
Domain Architecture
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B) (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa).

TRIM9_MOUSE
NC score	0.051425 (rank : 69)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	175	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRIM9_HUMAN
NC score	0.051346 (rank : 70)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	175	Target Neighborhood Hits	294	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

SDF2_HUMAN
NC score	0.051064 (rank : 71)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	175	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q99470, Q9BQ79	Gene names	SDF2
Domain Architecture
Description	Stromal cell-derived factor 2 precursor (SDF-2).

ONCO_HUMAN
NC score	0.050876 (rank : 72)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	175	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

SPRY3_HUMAN
NC score	0.050027 (rank : 73)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	175	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NCJ5, Q96SK5	Gene names	SPRYD3
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 3.

MLE1_HUMAN
NC score	0.049632 (rank : 74)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	175	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	P05976	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

SDF2_MOUSE
NC score	0.048861 (rank : 75)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	175	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCT5, P97307	Gene names	Sdf2
Domain Architecture
Description	Stromal cell-derived factor 2 precursor (SDF-2).

CND3_HUMAN
NC score	0.045830 (rank : 76)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	175	Target Neighborhood Hits	74	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BPX3, Q96SV9, Q9BUR3, Q9BVY1, Q9H914, Q9H9Z6, Q9HBI9	Gene names	NCAPG, CAPG, NYMEL3
Domain Architecture
Description	Condensin complex subunit 3 (Non-SMC condensin I complex subunit G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (XCAP-G homolog) (Antigen NY-MEL-3).

IWS1_MOUSE
NC score	0.045687 (rank : 77)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	175	Target Neighborhood Hits	1258	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SDF2L_MOUSE
NC score	0.043488 (rank : 78)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	175	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESP1, Q9ESP2	Gene names	Sdf2l1
Domain Architecture
Description	Stromal cell-derived factor 2-like protein 1 precursor (SDF2-like protein 1).

SOMA_HUMAN
NC score	0.041995 (rank : 79)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	175	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	P01241, Q14405, Q16631, Q5EB53, Q9HBZ1, Q9UMJ7, Q9UNL5	Gene names	GH1
Domain Architecture
Description	Somatotropin precursor (Growth hormone) (GH) (GH-N) (Pituitary growth hormone) (Growth hormone 1).

EFHB_MOUSE
NC score	0.041430 (rank : 80)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	175	Target Neighborhood Hits	120	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

SPRY4_MOUSE
NC score	0.040663 (rank : 81)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	175	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

PLSL_MOUSE
NC score	0.039428 (rank : 82)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	175	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

PLSL_HUMAN
NC score	0.039336 (rank : 83)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	175	Target Neighborhood Hits	168	Shared Neighborhood Hits	32
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

HMGN1_HUMAN
NC score	0.039154 (rank : 84)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	175	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P05114, Q3KQR8	Gene names	HMGN1, HMG14
Domain Architecture	No domain graphic available
Description	Nonhistone chromosomal protein HMG-14 (High-mobility group nucleosome- binding domain-containing protein 1).

SDF2L_HUMAN
NC score	0.037981 (rank : 85)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	175	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCN8, Q9BRI5	Gene names	SDF2L1
Domain Architecture
Description	Stromal cell-derived factor 2-like protein 1 precursor (SDF2-like protein 1) (PWP1-interacting protein 8).

AIF1_HUMAN
NC score	0.036336 (rank : 86)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	175	Target Neighborhood Hits	44	Shared Neighborhood Hits	19
SwissProt Accessions	P55008, Q9UKS9	Gene names	AIF1, G1, IBA1
Domain Architecture
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1).

CAYP2_HUMAN
NC score	0.035376 (rank : 87)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	175	Target Neighborhood Hits	98	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

EGLX_HUMAN
NC score	0.033756 (rank : 88)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	175	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NXG6, Q6PAG6, Q8TCJ9, Q8WV55, Q96F22, Q9BW77	Gene names	PH4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

RM40_MOUSE
NC score	0.033712 (rank : 89)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	175	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2Q5, Q9CS52	Gene names	Mrpl40, Nlvcf
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L40, mitochondrial precursor (L40mt) (MRP-40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog).

EGLX_MOUSE
NC score	0.032144 (rank : 90)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	175	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BG58, Q8CAF1, Q9D499	Gene names	Ph4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

XRCC4_HUMAN
NC score	0.031893 (rank : 91)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	175	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

PRP40_HUMAN
NC score	0.031151 (rank : 92)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	175	Target Neighborhood Hits	442	Shared Neighborhood Hits	20
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

IWS1_HUMAN
NC score	0.029616 (rank : 93)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	175	Target Neighborhood Hits	1241	Shared Neighborhood Hits	32
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ZCPW1_HUMAN
NC score	0.028517 (rank : 94)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	175	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

NKTR_MOUSE
NC score	0.027944 (rank : 95)	θ value	0.0193708 (rank : 22)
Query Neighborhood Hits	175	Target Neighborhood Hits	417	Shared Neighborhood Hits	14
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

LETM1_HUMAN
NC score	0.026238 (rank : 96)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	175	Target Neighborhood Hits	338	Shared Neighborhood Hits	18
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

UBCP1_HUMAN
NC score	0.026229 (rank : 97)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	175	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVY7, Q96DK5	Gene names	UBLCP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16).

UBCP1_MOUSE
NC score	0.026226 (rank : 98)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	175	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGR9, Q52L62, Q5XJH1, Q6PH96, Q99LT3	Gene names	Ublcp1
Domain Architecture	No domain graphic available
Description	Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16).

MPP8_HUMAN
NC score	0.025141 (rank : 99)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	175	Target Neighborhood Hits	948	Shared Neighborhood Hits	32
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

PCAT1_HUMAN
NC score	0.025103 (rank : 100)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	175	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NF37, Q1HAQ1, Q7Z4G6, Q8N3U7, Q8WUL8, Q9GZW6	Gene names	AYTL2, LPCAT1, PFAAP3
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3).

MYPT1_HUMAN
NC score	0.024030 (rank : 101)	θ value	0.0193708 (rank : 21)
Query Neighborhood Hits	175	Target Neighborhood Hits	723	Shared Neighborhood Hits	28
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

UBP47_MOUSE
NC score	0.023286 (rank : 102)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	175	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

CPNS2_MOUSE
NC score	0.023089 (rank : 103)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	175	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

UBP47_HUMAN
NC score	0.022298 (rank : 104)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	175	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

MYST3_HUMAN
NC score	0.021969 (rank : 105)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	175	Target Neighborhood Hits	772	Shared Neighborhood Hits	20
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

CAN2_MOUSE
NC score	0.021960 (rank : 106)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	175	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

CH60_MOUSE
NC score	0.021791 (rank : 107)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	175	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

CLSPN_HUMAN
NC score	0.021781 (rank : 108)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	175	Target Neighborhood Hits	433	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CAN3_MOUSE
NC score	0.021460 (rank : 109)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	175	Target Neighborhood Hits	115	Shared Neighborhood Hits	22
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

PPE1_HUMAN
NC score	0.021011 (rank : 110)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	175	Target Neighborhood Hits	137	Shared Neighborhood Hits	23
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

MYCD_MOUSE
NC score	0.020946 (rank : 111)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	175	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

CAN3_HUMAN
NC score	0.019782 (rank : 112)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	175	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

LETM1_MOUSE
NC score	0.019695 (rank : 113)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	175	Target Neighborhood Hits	240	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

CAN2_HUMAN
NC score	0.019671 (rank : 114)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	175	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

RRP5_HUMAN
NC score	0.019298 (rank : 115)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	175	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

MYCD_HUMAN
NC score	0.019136 (rank : 116)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	175	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

MYPT1_MOUSE
NC score	0.019121 (rank : 117)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	175	Target Neighborhood Hits	539	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

NASP_HUMAN
NC score	0.019057 (rank : 118)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	175	Target Neighborhood Hits	709	Shared Neighborhood Hits	30
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SFRIP_HUMAN
NC score	0.018307 (rank : 119)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	175	Target Neighborhood Hits	530	Shared Neighborhood Hits	13
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

TRPC6_HUMAN
NC score	0.018054 (rank : 120)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	175	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

N4BP2_HUMAN
NC score	0.017959 (rank : 121)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	175	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

NIBA_HUMAN
NC score	0.017905 (rank : 122)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	175	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

MEP50_MOUSE
NC score	0.017886 (rank : 123)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	175	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

TRPC4_HUMAN
NC score	0.017735 (rank : 124)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	175	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.017676 (rank : 125)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	175	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

NEB2_HUMAN
NC score	0.017603 (rank : 126)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	175	Target Neighborhood Hits	883	Shared Neighborhood Hits	22
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SESN2_HUMAN
NC score	0.017594 (rank : 127)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	175	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

GOGB1_HUMAN
NC score	0.017276 (rank : 128)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	175	Target Neighborhood Hits	2297	Shared Neighborhood Hits	49
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TBCD1_MOUSE
NC score	0.017211 (rank : 129)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	175	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

SPTN4_HUMAN
NC score	0.016581 (rank : 130)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	175	Target Neighborhood Hits	570	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

TRPC6_MOUSE
NC score	0.016267 (rank : 131)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	175	Target Neighborhood Hits	171	Shared Neighborhood Hits	9
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

CSH_HUMAN
NC score	0.015976 (rank : 132)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	175	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P01243, Q14407	Gene names	CSH1
Domain Architecture
Description	Chorionic somatomammotropin hormone precursor (Choriomammotropin) (Lactogen).

ADA30_HUMAN
NC score	0.015382 (rank : 133)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	175	Target Neighborhood Hits	391	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

DPOD4_MOUSE
NC score	0.015336 (rank : 134)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	175	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CWP8	Gene names	Pold4
Domain Architecture
Description	DNA polymerase subunit delta 4 (DNA polymerase subunit delta p12).

NEB2_MOUSE
NC score	0.015193 (rank : 135)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	175	Target Neighborhood Hits	889	Shared Neighborhood Hits	21
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

CJ118_MOUSE
NC score	0.014616 (rank : 136)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	175	Target Neighborhood Hits	1132	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

IQGA1_MOUSE
NC score	0.014603 (rank : 137)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	175	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

TRPC3_MOUSE
NC score	0.014386 (rank : 138)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	175	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

SMC4_HUMAN
NC score	0.013683 (rank : 139)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	175	Target Neighborhood Hits	937	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

UNC5B_MOUSE
NC score	0.013668 (rank : 140)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	175	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
NC score	0.013662 (rank : 141)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	175	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

MKL2_MOUSE
NC score	0.013324 (rank : 142)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	175	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

MYST3_MOUSE
NC score	0.013284 (rank : 143)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	175	Target Neighborhood Hits	688	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

DNMT1_HUMAN
NC score	0.012821 (rank : 144)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	175	Target Neighborhood Hits	401	Shared Neighborhood Hits	16
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

CCD38_HUMAN
NC score	0.012569 (rank : 145)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	175	Target Neighborhood Hits	287	Shared Neighborhood Hits	14
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

POT14_HUMAN
NC score	0.012473 (rank : 146)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	175	Target Neighborhood Hits	403	Shared Neighborhood Hits	16
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

CD33_MOUSE
NC score	0.012149 (rank : 147)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	175	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q63994, Q63997	Gene names	Cd33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3).

SNW1_MOUSE
NC score	0.011217 (rank : 148)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	175	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

ASM_HUMAN
NC score	0.011215 (rank : 149)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	175	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P17405, P17406, Q13811, Q16837, Q16841	Gene names	SMPD1, ASM
Domain Architecture
Description	Sphingomyelin phosphodiesterase precursor (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase).

SC11A_MOUSE
NC score	0.010951 (rank : 150)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	175	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

NCOR2_MOUSE
NC score	0.010924 (rank : 151)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	175	Target Neighborhood Hits	790	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

POGK_MOUSE
NC score	0.010631 (rank : 152)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	175	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TC5, Q8BPJ3, Q8C887	Gene names	Pogk, Kiaa1513
Domain Architecture
Description	Pogo transposable element with KRAB domain.

CP135_MOUSE
NC score	0.010609 (rank : 153)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	175	Target Neighborhood Hits	1278	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DOCK1_HUMAN
NC score	0.010551 (rank : 154)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	175	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

CEP72_HUMAN
NC score	0.010483 (rank : 155)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	175	Target Neighborhood Hits	374	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

WDR7_HUMAN
NC score	0.010365 (rank : 156)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	175	Target Neighborhood Hits	244	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

VATC_MOUSE
NC score	0.010151 (rank : 157)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	175	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1G3	Gene names	Atp6v1c1, Atp6c, Vatc
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

SMRCD_MOUSE
NC score	0.009881 (rank : 158)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	175	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

ANKR5_MOUSE
NC score	0.009611 (rank : 159)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	175	Target Neighborhood Hits	298	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

EXOC8_HUMAN
NC score	0.009178 (rank : 160)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	175	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYI6, Q5TE82	Gene names	EXOC8
Domain Architecture	No domain graphic available
Description	Exocyst complex component 8 (Exocyst complex 84 kDa subunit).

CENPF_HUMAN
NC score	0.009036 (rank : 161)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	175	Target Neighborhood Hits	1932	Shared Neighborhood Hits	43
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

LYST_HUMAN
NC score	0.008578 (rank : 162)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	175	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

EP15R_MOUSE
NC score	0.008361 (rank : 163)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	175	Target Neighborhood Hits	1135	Shared Neighborhood Hits	36
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

TYRO_MOUSE
NC score	0.007958 (rank : 164)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	175	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

TXLNA_MOUSE
NC score	0.007803 (rank : 165)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	175	Target Neighborhood Hits	846	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

BCOR_HUMAN
NC score	0.007721 (rank : 166)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	175	Target Neighborhood Hits	609	Shared Neighborhood Hits	16
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

UT14B_MOUSE
NC score	0.007592 (rank : 167)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	175	Target Neighborhood Hits	226	Shared Neighborhood Hits	13
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

EEA1_MOUSE
NC score	0.007438 (rank : 168)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	175	Target Neighborhood Hits	1637	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

TEX14_HUMAN
NC score	0.006942 (rank : 169)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	175	Target Neighborhood Hits	1103	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

RIMS1_HUMAN
NC score	0.006841 (rank : 170)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	175	Target Neighborhood Hits	437	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

MYH10_MOUSE
NC score	0.006768 (rank : 171)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	175	Target Neighborhood Hits	1612	Shared Neighborhood Hits	36
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

FIGN_MOUSE
NC score	0.006728 (rank : 172)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	175	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

ATX2_MOUSE
NC score	0.006706 (rank : 173)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	175	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CYLN2_HUMAN
NC score	0.006412 (rank : 174)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	175	Target Neighborhood Hits	1004	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

MYH11_HUMAN
NC score	0.006373 (rank : 175)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	175	Target Neighborhood Hits	1806	Shared Neighborhood Hits	40
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

UACA_MOUSE
NC score	0.006271 (rank : 176)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	175	Target Neighborhood Hits	1620	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

TAF1_HUMAN
NC score	0.006222 (rank : 177)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	175	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

MYH10_HUMAN
NC score	0.005895 (rank : 178)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	175	Target Neighborhood Hits	1620	Shared Neighborhood Hits	33
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ARHG3_HUMAN
NC score	0.005859 (rank : 179)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	175	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
NC score	0.005856 (rank : 180)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	175	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

POK7_HUMAN
NC score	0.005199 (rank : 181)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	175	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

JHD3C_MOUSE
NC score	0.003896 (rank : 182)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	175	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

SUHW4_HUMAN
NC score	0.003032 (rank : 183)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	175	Target Neighborhood Hits	860	Shared Neighborhood Hits	15
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

PTN13_MOUSE
NC score	0.001490 (rank : 184)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	175	Target Neighborhood Hits	426	Shared Neighborhood Hits	6
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

ZN586_HUMAN
NC score	0.000266 (rank : 185)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	175	Target Neighborhood Hits	637	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NXT0	Gene names	ZNF586
Domain Architecture	No domain graphic available
Description	Zinc finger protein 586.

BSH_MOUSE
NC score	0.000204 (rank : 186)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	175	Target Neighborhood Hits	349	Shared Neighborhood Hits	2
SwissProt Accessions	Q810B3	Gene names	Bsx
Domain Architecture	No domain graphic available
Description	Brain-specific homeobox protein homolog.

LIMK2_HUMAN
NC score	-0.000714 (rank : 187)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	175	Target Neighborhood Hits	986	Shared Neighborhood Hits	7
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

ST17A_HUMAN
NC score	-0.000939 (rank : 188)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	175	Target Neighborhood Hits	843	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UEE5, Q8IVC8	Gene names	STK17A, DRAK1
Domain Architecture
Description	Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1).

ZFP59_MOUSE
NC score	-0.001708 (rank : 189)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	175	Target Neighborhood Hits	768	Shared Neighborhood Hits	7
SwissProt Accessions	P16373, Q61849	Gene names	Zfp59, Mfg2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 59 (Zfp-59) (Zinc finger protein Mfg-2).

ZN366_HUMAN
NC score	-0.002145 (rank : 190)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	175	Target Neighborhood Hits	732	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.

ZBT40_HUMAN
NC score	-0.002221 (rank : 191)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	175	Target Neighborhood Hits	949	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

FAK2_MOUSE
NC score	-0.002272 (rank : 192)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	175	Target Neighborhood Hits	851	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).