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Network neighborhood for query Sequence : SPRY3_HUMAN

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SPRY3_HUMAN
SwissProt Accessions	Q8NCJ5, Q96SK5	Gene names	SPRYD3
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPRY3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NCJ5, Q96SK5	Gene names	SPRYD3
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 3.

RANB9_HUMAN
θ value	1.80466e-16 (rank : 2)	NC score	0.537136 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	179	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RANB9_MOUSE
θ value	1.80466e-16 (rank : 3)	NC score	0.566358 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	P69566	Gene names	Ranbp9, Ranbpm
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (Ran-binding protein M) (RanBPM) (B cell antigen receptor Ig beta-associated protein 1) (IBAP-1).

DDX1_HUMAN
θ value	0.47712 (rank : 4)	NC score	0.064678 (rank : 10)
Query Neighborhood Hits	9	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

PAHX_MOUSE
θ value	0.47712 (rank : 5)	NC score	0.075688 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	O35386, O08527	Gene names	Phyh, Ln1, Lnap1, Pahx
Domain Architecture
Description	Phytanoyl-CoA dioxygenase, peroxisomal precursor (EC 1.14.11.18) (Phytanoyl-CoA alpha-hydroxylase) (PhyH) (Phytanic acid oxidase) (Lupus nephritis-associated peptide 1).

NSBP1_MOUSE
θ value	1.06291 (rank : 6)	NC score	0.034030 (rank : 15)
Query Neighborhood Hits	9	Target Neighborhood Hits	681	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

RYR1_HUMAN
θ value	1.81305 (rank : 7)	NC score	0.067072 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	303	Shared Neighborhood Hits	7
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

DDX1_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.056528 (rank : 11)
Query Neighborhood Hits	9	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

TRI22_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.005646 (rank : 16)
Query Neighborhood Hits	9	Target Neighborhood Hits	396	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

ASH2L_HUMAN
θ value	θ > 10 (rank : 10)	NC score	0.053094 (rank : 13)
Query Neighborhood Hits	9	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ASH2L_MOUSE
θ value	θ > 10 (rank : 11)	NC score	0.053175 (rank : 12)
Query Neighborhood Hits	9	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

CT011_HUMAN
θ value	θ > 10 (rank : 12)	NC score	0.091044 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWU2, Q8N5M5	Gene names	C20orf11
Domain Architecture
Description	Protein C20orf11 (Two-hybrid associated protein 1 with RanBPM) (Twa1).

CT011_MOUSE
θ value	θ > 10 (rank : 13)	NC score	0.091072 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7M1	Gene names
Domain Architecture
Description	Protein C20orf11 homolog (Two-hybrid associated protein 1 with RanBPM) (Twa1).

RN123_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.068356 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 15)	NC score	0.065986 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RYR2_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.050027 (rank : 14)
Query Neighborhood Hits	9	Target Neighborhood Hits	175	Shared Neighborhood Hits	5
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

Hits sorted by NC score

SPRY3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NCJ5, Q96SK5	Gene names	SPRYD3
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 3.

RANB9_MOUSE
NC score	0.566358 (rank : 2)	θ value	1.80466e-16 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	P69566	Gene names	Ranbp9, Ranbpm
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (Ran-binding protein M) (RanBPM) (B cell antigen receptor Ig beta-associated protein 1) (IBAP-1).

RANB9_HUMAN
NC score	0.537136 (rank : 3)	θ value	1.80466e-16 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	179	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

CT011_MOUSE
NC score	0.091072 (rank : 4)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	9	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7M1	Gene names
Domain Architecture
Description	Protein C20orf11 homolog (Two-hybrid associated protein 1 with RanBPM) (Twa1).

CT011_HUMAN
NC score	0.091044 (rank : 5)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	9	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWU2, Q8N5M5	Gene names	C20orf11
Domain Architecture
Description	Protein C20orf11 (Two-hybrid associated protein 1 with RanBPM) (Twa1).

PAHX_MOUSE
NC score	0.075688 (rank : 6)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	O35386, O08527	Gene names	Phyh, Ln1, Lnap1, Pahx
Domain Architecture
Description	Phytanoyl-CoA dioxygenase, peroxisomal precursor (EC 1.14.11.18) (Phytanoyl-CoA alpha-hydroxylase) (PhyH) (Phytanic acid oxidase) (Lupus nephritis-associated peptide 1).

RN123_HUMAN
NC score	0.068356 (rank : 7)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	9	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RYR1_HUMAN
NC score	0.067072 (rank : 8)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	303	Shared Neighborhood Hits	7
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

RN123_MOUSE
NC score	0.065986 (rank : 9)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	9	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

DDX1_HUMAN
NC score	0.064678 (rank : 10)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
NC score	0.056528 (rank : 11)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

ASH2L_MOUSE
NC score	0.053175 (rank : 12)	θ value	θ > 10 (rank : 11)
Query Neighborhood Hits	9	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ASH2L_HUMAN
NC score	0.053094 (rank : 13)	θ value	θ > 10 (rank : 10)
Query Neighborhood Hits	9	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

RYR2_HUMAN
NC score	0.050027 (rank : 14)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	9	Target Neighborhood Hits	175	Shared Neighborhood Hits	5
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

NSBP1_MOUSE
NC score	0.034030 (rank : 15)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	681	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

TRI22_HUMAN
NC score	0.005646 (rank : 16)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	396	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).