Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : ASH2L_MOUSE

For an explanation of this page, click here

ASH2L_MOUSE
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ASH2L_HUMAN
θ value	0 (rank : 1)	NC score	0.993403 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ASH2L_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

RYR3_HUMAN
θ value	2.88788e-06 (rank : 3)	NC score	0.267440 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

RN123_HUMAN
θ value	4.92598e-06 (rank : 4)	NC score	0.320079 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RYR2_HUMAN
θ value	1.09739e-05 (rank : 5)	NC score	0.267962 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	175	Shared Neighborhood Hits	13
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

RN123_MOUSE
θ value	1.43324e-05 (rank : 6)	NC score	0.313874 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RYR1_HUMAN
θ value	3.19293e-05 (rank : 7)	NC score	0.258955 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	303	Shared Neighborhood Hits	17
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

HNRL1_HUMAN
θ value	9.29e-05 (rank : 8)	NC score	0.264971 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
θ value	9.29e-05 (rank : 9)	NC score	0.264442 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

RANB9_HUMAN
θ value	0.000270298 (rank : 10)	NC score	0.266998 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RANB9_MOUSE
θ value	0.000270298 (rank : 11)	NC score	0.280048 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	P69566	Gene names	Ranbp9, Ranbpm
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (Ran-binding protein M) (RanBPM) (B cell antigen receptor Ig beta-associated protein 1) (IBAP-1).

HNRPU_HUMAN
θ value	0.00228821 (rank : 12)	NC score	0.246908 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

CSR2B_HUMAN
θ value	0.0113563 (rank : 13)	NC score	0.165476 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H8E8, Q96GW6, Q96IH3, Q9HBF0, Q9UIY5	Gene names	CSRP2BP
Domain Architecture
Description	Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (CRP2BP) (CRP2-binding partner).

RBBP6_HUMAN
θ value	0.0431538 (rank : 14)	NC score	0.058480 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	1135	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

PGCA_MOUSE
θ value	0.0961366 (rank : 15)	NC score	0.042154 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	643	Shared Neighborhood Hits	12
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

MINT_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.035249 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	1514	Shared Neighborhood Hits	14
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PGCA_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.035053 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	821	Shared Neighborhood Hits	12
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LBXCO_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.031530 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

NSD1_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.031342 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	472	Shared Neighborhood Hits	7
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

OGFR_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.031221 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	1582	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ZIMP7_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.037708 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	290	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

DEND_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.032536 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

DOT1L_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.031369 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	660	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GRIN1_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.032003 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	337	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SON_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.021237 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	1568	Shared Neighborhood Hits	14
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TRIM9_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.034823 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

CLIC6_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.024382 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	289	Shared Neighborhood Hits	11
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

DNAI1_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.031253 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI46, Q9UEZ8	Gene names	DNAI1
Domain Architecture
Description	Dynein intermediate chain 1, axonemal (Axonemal dynein intermediate chain 1).

EDD1_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.023588 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

EDD1_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.022364 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

HDAC6_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.011846 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

MUCDL_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.013797 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	461	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PHF1_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.035611 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.035479 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

X3CL1_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.040893 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	152	Shared Neighborhood Hits	6
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

EXOC6_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.014401 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R313	Gene names	Exoc6, Sec15a, Sec15l1
Domain Architecture
Description	Exocyst complex component 6 (Exocyst complex component Sec15A) (Sec15- like 1).

CTDP1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.014529 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	416	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

HTF4_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.009125 (rank : 43)
Query Neighborhood Hits	40	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

SEC13_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.013279 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	P55735, Q9BRM6, Q9BUG7	Gene names	SEC13L1, SEC13R
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

TRIM9_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.028873 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	274	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

DDX1_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.062699 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.060839 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

SPRY3_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.053175 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NCJ5, Q96SK5	Gene names	SPRYD3
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 3.

Hits sorted by NC score

ASH2L_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ASH2L_HUMAN
NC score	0.993403 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

RN123_HUMAN
NC score	0.320079 (rank : 3)	θ value	4.92598e-06 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
NC score	0.313874 (rank : 4)	θ value	1.43324e-05 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RANB9_MOUSE
NC score	0.280048 (rank : 5)	θ value	0.000270298 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	P69566	Gene names	Ranbp9, Ranbpm
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (Ran-binding protein M) (RanBPM) (B cell antigen receptor Ig beta-associated protein 1) (IBAP-1).

RYR2_HUMAN
NC score	0.267962 (rank : 6)	θ value	1.09739e-05 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	175	Shared Neighborhood Hits	13
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

RYR3_HUMAN
NC score	0.267440 (rank : 7)	θ value	2.88788e-06 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

RANB9_HUMAN
NC score	0.266998 (rank : 8)	θ value	0.000270298 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

HNRL1_HUMAN
NC score	0.264971 (rank : 9)	θ value	9.29e-05 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
NC score	0.264442 (rank : 10)	θ value	9.29e-05 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

RYR1_HUMAN
NC score	0.258955 (rank : 11)	θ value	3.19293e-05 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	303	Shared Neighborhood Hits	17
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

HNRPU_HUMAN
NC score	0.246908 (rank : 12)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

CSR2B_HUMAN
NC score	0.165476 (rank : 13)	θ value	0.0113563 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H8E8, Q96GW6, Q96IH3, Q9HBF0, Q9UIY5	Gene names	CSRP2BP
Domain Architecture
Description	Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (CRP2BP) (CRP2-binding partner).

DDX1_HUMAN
NC score	0.062699 (rank : 14)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
NC score	0.060839 (rank : 15)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

RBBP6_HUMAN
NC score	0.058480 (rank : 16)	θ value	0.0431538 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	1135	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SPRY3_HUMAN
NC score	0.053175 (rank : 17)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	40	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NCJ5, Q96SK5	Gene names	SPRYD3
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 3.

PGCA_MOUSE
NC score	0.042154 (rank : 18)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	643	Shared Neighborhood Hits	12
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

X3CL1_HUMAN
NC score	0.040893 (rank : 19)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	152	Shared Neighborhood Hits	6
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ZIMP7_HUMAN
NC score	0.037708 (rank : 20)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	290	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

PHF1_HUMAN
NC score	0.035611 (rank : 21)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
NC score	0.035479 (rank : 22)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

MINT_MOUSE
NC score	0.035249 (rank : 23)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	1514	Shared Neighborhood Hits	14
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PGCA_HUMAN
NC score	0.035053 (rank : 24)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	821	Shared Neighborhood Hits	12
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

TRIM9_HUMAN
NC score	0.034823 (rank : 25)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	294	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

DEND_HUMAN
NC score	0.032536 (rank : 26)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

GRIN1_MOUSE
NC score	0.032003 (rank : 27)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	337	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

LBXCO_MOUSE
NC score	0.031530 (rank : 28)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

DOT1L_HUMAN
NC score	0.031369 (rank : 29)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	660	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

NSD1_MOUSE
NC score	0.031342 (rank : 30)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	472	Shared Neighborhood Hits	7
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

DNAI1_HUMAN
NC score	0.031253 (rank : 31)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI46, Q9UEZ8	Gene names	DNAI1
Domain Architecture
Description	Dynein intermediate chain 1, axonemal (Axonemal dynein intermediate chain 1).

OGFR_HUMAN
NC score	0.031221 (rank : 32)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	1582	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TRIM9_MOUSE
NC score	0.028873 (rank : 33)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	274	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

CLIC6_HUMAN
NC score	0.024382 (rank : 34)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	289	Shared Neighborhood Hits	11
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

EDD1_MOUSE
NC score	0.023588 (rank : 35)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

EDD1_HUMAN
NC score	0.022364 (rank : 36)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

SON_HUMAN
NC score	0.021237 (rank : 37)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	1568	Shared Neighborhood Hits	14
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CTDP1_HUMAN
NC score	0.014529 (rank : 38)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	416	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

EXOC6_MOUSE
NC score	0.014401 (rank : 39)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R313	Gene names	Exoc6, Sec15a, Sec15l1
Domain Architecture
Description	Exocyst complex component 6 (Exocyst complex component Sec15A) (Sec15- like 1).

MUCDL_MOUSE
NC score	0.013797 (rank : 40)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	461	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SEC13_HUMAN
NC score	0.013279 (rank : 41)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	P55735, Q9BRM6, Q9BUG7	Gene names	SEC13L1, SEC13R
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

HDAC6_HUMAN
NC score	0.011846 (rank : 42)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

HTF4_MOUSE
NC score	0.009125 (rank : 43)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).