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Network neighborhood for query Sequence : ARRD1_HUMAN

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ARRD1_HUMAN
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARRD1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ARRD1_MOUSE
θ value	0 (rank : 2)	NC score	0.973047 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	24
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ARRD2_MOUSE
θ value	2.87452e-22 (rank : 3)	NC score	0.752141 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D668, Q3UVK8, Q3UXC6	Gene names	Arrdc2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

ARRD2_HUMAN
θ value	1.86321e-21 (rank : 4)	NC score	0.743263 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TBH0, O95895, Q6ZRV9, Q8WYG6	Gene names	ARRDC2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

ARRD4_HUMAN
θ value	1.2077e-20 (rank : 5)	NC score	0.733857 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NCT1, Q6NSI9	Gene names	ARRDC4
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 4.

ARRD3_MOUSE
θ value	3.51386e-20 (rank : 6)	NC score	0.724447 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TPQ9, Q4KMN0, Q80TE6, Q8K0L7	Gene names	Arrdc3, Kiaa1376
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 3.

ARRD3_HUMAN
θ value	4.58923e-20 (rank : 7)	NC score	0.721563 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q96B67, Q9P2H1	Gene names	ARRDC3, KIAA1376
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 3.

TXNIP_HUMAN
θ value	2.60593e-15 (rank : 8)	NC score	0.696128 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3M7, Q16226, Q6PML0, Q9BXG9	Gene names	TXNIP, VDUP1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1) (Thioredoxin-binding protein 2).

TXNIP_MOUSE
θ value	1.29331e-14 (rank : 9)	NC score	0.693026 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BG60, Q8BGQ0, Q8K2B2, Q9DC00, Q9EP90, Q9R115	Gene names	Txnip, Vdup1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1).

ARRD5_MOUSE
θ value	7.59969e-07 (rank : 10)	NC score	0.523572 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q497K5	Gene names	Arrdc5
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 5.

ARRB2_HUMAN
θ value	0.0148317 (rank : 11)	NC score	0.117430 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	P32121, Q0Z8D3, Q2PP19, Q6ICT3, Q8N7Y2, Q9UEQ6	Gene names	ARRB2, ARB2, ARR2
Domain Architecture
Description	Beta-arrestin-2 (Arrestin beta 2).

ARRB2_MOUSE
θ value	0.0431538 (rank : 12)	NC score	0.107866 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YI4, Q3TCM2, Q5F2D8, Q5F2E0	Gene names	Arrb2
Domain Architecture
Description	Beta-arrestin-2 (Arrestin beta 2).

RP1L1_HUMAN
θ value	0.0563607 (rank : 13)	NC score	0.038225 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	1072	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ARRB1_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.115608 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P49407, O75625, O75630, Q2PP20, Q9BTK8	Gene names	ARRB1, ARR1
Domain Architecture
Description	Beta-arrestin-1 (Arrestin beta 1).

DSCR3_MOUSE
θ value	0.0961366 (rank : 15)	NC score	0.138337 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O35075, Q542V5	Gene names	Dscr3, Dcra, Dscra
Domain Architecture
Description	Down syndrome critical region protein 3 homolog (Down syndrome critical region protein A homolog).

MDC1_HUMAN
θ value	0.0961366 (rank : 16)	NC score	0.045382 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	1446	Shared Neighborhood Hits	39
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

DSCR3_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.135726 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O14972	Gene names	DSCR3, DCRA, DSCRA
Domain Architecture
Description	Down syndrome critical region protein 3 (Down syndrome critical region protein A).

ARRB1_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.101323 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BWG8, Q3UH95, Q8BTJ5	Gene names	Arrb1
Domain Architecture	No domain graphic available
Description	Beta-arrestin-1 (Arrestin beta 1).

FOSB_MOUSE
θ value	0.47712 (rank : 19)	NC score	0.033562 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

SPR2H_MOUSE
θ value	0.47712 (rank : 20)	NC score	0.049252 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

CA106_MOUSE
θ value	0.62314 (rank : 21)	NC score	0.048459 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

MLL3_MOUSE
θ value	0.813845 (rank : 22)	NC score	0.033381 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	1399	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

WASF2_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.038906 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

MYCD_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.030443 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

PEF1_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.022774 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PAX3_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.014350 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	513	Shared Neighborhood Hits	11
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

CIC_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.039716 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	992	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.039169 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	742	Shared Neighborhood Hits	24
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LATS1_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.003805 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	1027	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

MLL2_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.045382 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	1788	Shared Neighborhood Hits	29
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PASK_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.003679 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	857	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

PAX3_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.013212 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

PK1L1_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.030349 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PRGC1_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.047550 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

ANX11_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.011596 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	192	Shared Neighborhood Hits	9
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

CC062_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.032320 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZUJ4, Q6P7E9, Q7Z3X6	Gene names	C3orf62
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf62.

CSKI1_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.021819 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	1031	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EGR1_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.001289 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	816	Shared Neighborhood Hits	5
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

ENAH_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.021805 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	919	Shared Neighborhood Hits	20
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FYB_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.027474 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

RERE_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.024229 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	779	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

CA106_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.039215 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

MINT_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.019216 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	1291	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PRGC1_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.046481 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	238	Shared Neighborhood Hits	10
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

TAF4_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.031034 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	687	Shared Neighborhood Hits	18
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

WASF2_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.035936 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	315	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

BMP3B_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.017743 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	P97737	Gene names	Gdf10, Bmp3b
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10).

CSKI1_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.022427 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	997	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DIAP1_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.010983 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	784	Shared Neighborhood Hits	12
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

PCQAP_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.020948 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	549	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

SPR1A_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.027428 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

ADAM8_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.004382 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	326	Shared Neighborhood Hits	3
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

BMP3B_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.017044 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P55107, Q9UCX6	Gene names	GDF10, BMP3B
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10) (Bone-inducing protein) (BIP).

BMP3_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.015048 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	P12645	Gene names	BMP3
Domain Architecture
Description	Bone morphogenetic protein 3 precursor (BMP-3) (Osteogenin) (BMP-3A).

BRSK1_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.000512 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	942	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

EHMT2_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.010199 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	750	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

LBXCO_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.015251 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

MEGF9_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.011227 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	896	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MYO15_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.009729 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	671	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PTCD1_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.018914 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

SPR2E_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.030316 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

ALEX_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.024991 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	361	Shared Neighborhood Hits	18
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ARVC_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.007649 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

BAG4_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.015292 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

CEND_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.024997 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

GA2L1_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.013193 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

K0460_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.017261 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

TRPV2_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.014081 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

AB1IP_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.009301 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

CN004_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.017625 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

CN032_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.016422 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	267	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

LIMD1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.005244 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

LRC50_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.011509 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MKL1_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.022037 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	667	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

WASF4_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.031602 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	282	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

ARRC_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.062368 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P36575, Q5JT23, Q5JT24, Q6IBF5, Q96EN2	Gene names	ARR3, ARRX, CAR
Domain Architecture
Description	Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3) (X- arrestin) (C-arrestin).

ARRC_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.086424 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQP6	Gene names	Arr3
Domain Architecture
Description	Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3).

ARRS_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.061924 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	P10523, Q53SV3, Q99858	Gene names	SAG
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

ARRS_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.064800 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P20443, Q91W62	Gene names	Sag
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

Hits sorted by NC score

ARRD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ARRD1_MOUSE
NC score	0.973047 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	24
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ARRD2_MOUSE
NC score	0.752141 (rank : 3)	θ value	2.87452e-22 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D668, Q3UVK8, Q3UXC6	Gene names	Arrdc2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

ARRD2_HUMAN
NC score	0.743263 (rank : 4)	θ value	1.86321e-21 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TBH0, O95895, Q6ZRV9, Q8WYG6	Gene names	ARRDC2
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 2.

ARRD4_HUMAN
NC score	0.733857 (rank : 5)	θ value	1.2077e-20 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NCT1, Q6NSI9	Gene names	ARRDC4
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 4.

ARRD3_MOUSE
NC score	0.724447 (rank : 6)	θ value	3.51386e-20 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TPQ9, Q4KMN0, Q80TE6, Q8K0L7	Gene names	Arrdc3, Kiaa1376
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 3.

ARRD3_HUMAN
NC score	0.721563 (rank : 7)	θ value	4.58923e-20 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q96B67, Q9P2H1	Gene names	ARRDC3, KIAA1376
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 3.

TXNIP_HUMAN
NC score	0.696128 (rank : 8)	θ value	2.60593e-15 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3M7, Q16226, Q6PML0, Q9BXG9	Gene names	TXNIP, VDUP1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1) (Thioredoxin-binding protein 2).

TXNIP_MOUSE
NC score	0.693026 (rank : 9)	θ value	1.29331e-14 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	11	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BG60, Q8BGQ0, Q8K2B2, Q9DC00, Q9EP90, Q9R115	Gene names	Txnip, Vdup1
Domain Architecture	No domain graphic available
Description	Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1).

ARRD5_MOUSE
NC score	0.523572 (rank : 10)	θ value	7.59969e-07 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q497K5	Gene names	Arrdc5
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 5.

DSCR3_MOUSE
NC score	0.138337 (rank : 11)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O35075, Q542V5	Gene names	Dscr3, Dcra, Dscra
Domain Architecture
Description	Down syndrome critical region protein 3 homolog (Down syndrome critical region protein A homolog).

DSCR3_HUMAN
NC score	0.135726 (rank : 12)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O14972	Gene names	DSCR3, DCRA, DSCRA
Domain Architecture
Description	Down syndrome critical region protein 3 (Down syndrome critical region protein A).

ARRB2_HUMAN
NC score	0.117430 (rank : 13)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	P32121, Q0Z8D3, Q2PP19, Q6ICT3, Q8N7Y2, Q9UEQ6	Gene names	ARRB2, ARB2, ARR2
Domain Architecture
Description	Beta-arrestin-2 (Arrestin beta 2).

ARRB1_HUMAN
NC score	0.115608 (rank : 14)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P49407, O75625, O75630, Q2PP20, Q9BTK8	Gene names	ARRB1, ARR1
Domain Architecture
Description	Beta-arrestin-1 (Arrestin beta 1).

ARRB2_MOUSE
NC score	0.107866 (rank : 15)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YI4, Q3TCM2, Q5F2D8, Q5F2E0	Gene names	Arrb2
Domain Architecture
Description	Beta-arrestin-2 (Arrestin beta 2).

ARRB1_MOUSE
NC score	0.101323 (rank : 16)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BWG8, Q3UH95, Q8BTJ5	Gene names	Arrb1
Domain Architecture	No domain graphic available
Description	Beta-arrestin-1 (Arrestin beta 1).

ARRC_MOUSE
NC score	0.086424 (rank : 17)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQP6	Gene names	Arr3
Domain Architecture
Description	Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3).

ARRS_MOUSE
NC score	0.064800 (rank : 18)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P20443, Q91W62	Gene names	Sag
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

ARRC_HUMAN
NC score	0.062368 (rank : 19)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P36575, Q5JT23, Q5JT24, Q6IBF5, Q96EN2	Gene names	ARR3, ARRX, CAR
Domain Architecture
Description	Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3) (X- arrestin) (C-arrestin).

ARRS_HUMAN
NC score	0.061924 (rank : 20)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	P10523, Q53SV3, Q99858	Gene names	SAG
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

SPR2H_MOUSE
NC score	0.049252 (rank : 21)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

CA106_MOUSE
NC score	0.048459 (rank : 22)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

PRGC1_HUMAN
NC score	0.047550 (rank : 23)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

PRGC1_MOUSE
NC score	0.046481 (rank : 24)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	238	Shared Neighborhood Hits	10
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

MDC1_HUMAN
NC score	0.045382 (rank : 25)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	1446	Shared Neighborhood Hits	39
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MLL2_HUMAN
NC score	0.045382 (rank : 26)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	1788	Shared Neighborhood Hits	29
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CIC_HUMAN
NC score	0.039716 (rank : 27)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	992	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CA106_HUMAN
NC score	0.039215 (rank : 28)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CIC_MOUSE
NC score	0.039169 (rank : 29)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	742	Shared Neighborhood Hits	24
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

WASF2_HUMAN
NC score	0.038906 (rank : 30)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

RP1L1_HUMAN
NC score	0.038225 (rank : 31)	θ value	0.0563607 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	1072	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

WASF2_MOUSE
NC score	0.035936 (rank : 32)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	315	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

FOSB_MOUSE
NC score	0.033562 (rank : 33)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

MLL3_MOUSE
NC score	0.033381 (rank : 34)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	1399	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CC062_HUMAN
NC score	0.032320 (rank : 35)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZUJ4, Q6P7E9, Q7Z3X6	Gene names	C3orf62
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf62.

WASF4_HUMAN
NC score	0.031602 (rank : 36)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	282	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

TAF4_HUMAN
NC score	0.031034 (rank : 37)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	687	Shared Neighborhood Hits	18
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MYCD_MOUSE
NC score	0.030443 (rank : 38)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

PK1L1_HUMAN
NC score	0.030349 (rank : 39)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

SPR2E_MOUSE
NC score	0.030316 (rank : 40)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

FYB_MOUSE
NC score	0.027474 (rank : 41)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

SPR1A_MOUSE
NC score	0.027428 (rank : 42)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	343	Shared Neighborhood Hits	20
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

CEND_HUMAN
NC score	0.024997 (rank : 43)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

ALEX_HUMAN
NC score	0.024991 (rank : 44)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	361	Shared Neighborhood Hits	18
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

RERE_HUMAN
NC score	0.024229 (rank : 45)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	779	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

PEF1_HUMAN
NC score	0.022774 (rank : 46)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

CSKI1_HUMAN
NC score	0.022427 (rank : 47)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	997	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MKL1_MOUSE
NC score	0.022037 (rank : 48)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	667	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

CSKI1_MOUSE
NC score	0.021819 (rank : 49)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	1031	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ENAH_MOUSE
NC score	0.021805 (rank : 50)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	919	Shared Neighborhood Hits	20
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PCQAP_HUMAN
NC score	0.020948 (rank : 51)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	549	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

MINT_HUMAN
NC score	0.019216 (rank : 52)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	1291	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PTCD1_HUMAN
NC score	0.018914 (rank : 53)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

BMP3B_MOUSE
NC score	0.017743 (rank : 54)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	P97737	Gene names	Gdf10, Bmp3b
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10).

CN004_MOUSE
NC score	0.017625 (rank : 55)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

K0460_MOUSE
NC score	0.017261 (rank : 56)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

BMP3B_HUMAN
NC score	0.017044 (rank : 57)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P55107, Q9UCX6	Gene names	GDF10, BMP3B
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10) (Bone-inducing protein) (BIP).

CN032_HUMAN
NC score	0.016422 (rank : 58)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	267	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

BAG4_HUMAN
NC score	0.015292 (rank : 59)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

LBXCO_HUMAN
NC score	0.015251 (rank : 60)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

BMP3_HUMAN
NC score	0.015048 (rank : 61)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	P12645	Gene names	BMP3
Domain Architecture
Description	Bone morphogenetic protein 3 precursor (BMP-3) (Osteogenin) (BMP-3A).

PAX3_HUMAN
NC score	0.014350 (rank : 62)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	513	Shared Neighborhood Hits	11
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

TRPV2_MOUSE
NC score	0.014081 (rank : 63)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

PAX3_MOUSE
NC score	0.013212 (rank : 64)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

GA2L1_MOUSE
NC score	0.013193 (rank : 65)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

ANX11_HUMAN
NC score	0.011596 (rank : 66)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	192	Shared Neighborhood Hits	9
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

LRC50_HUMAN
NC score	0.011509 (rank : 67)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MEGF9_MOUSE
NC score	0.011227 (rank : 68)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	896	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

DIAP1_HUMAN
NC score	0.010983 (rank : 69)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	784	Shared Neighborhood Hits	12
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

EHMT2_MOUSE
NC score	0.010199 (rank : 70)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	750	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MYO15_HUMAN
NC score	0.009729 (rank : 71)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	671	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

AB1IP_MOUSE
NC score	0.009301 (rank : 72)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ARVC_HUMAN
NC score	0.007649 (rank : 73)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

LIMD1_HUMAN
NC score	0.005244 (rank : 74)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

ADAM8_MOUSE
NC score	0.004382 (rank : 75)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	326	Shared Neighborhood Hits	3
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

LATS1_MOUSE
NC score	0.003805 (rank : 76)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	1027	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

PASK_HUMAN
NC score	0.003679 (rank : 77)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	857	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

EGR1_MOUSE
NC score	0.001289 (rank : 78)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	816	Shared Neighborhood Hits	5
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

BRSK1_HUMAN
NC score	0.000512 (rank : 79)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	942	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).