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Network neighborhood for query Sequence : CSKI1_MOUSE

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CSKI1_MOUSE
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CSKI1_HUMAN
θ value	0 (rank : 1)	NC score	0.976254 (rank : 2)
Query Neighborhood Hits	1031	Target Neighborhood Hits	997	Shared Neighborhood Hits	714
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1031	Shared Neighborhood Hits	1031
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
θ value	0 (rank : 3)	NC score	0.942212 (rank : 3)
Query Neighborhood Hits	1031	Target Neighborhood Hits	747	Shared Neighborhood Hits	520
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	0 (rank : 4)	NC score	0.941009 (rank : 4)
Query Neighborhood Hits	1031	Target Neighborhood Hits	812	Shared Neighborhood Hits	529
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKS1_HUMAN
θ value	2.58187e-47 (rank : 5)	NC score	0.879795 (rank : 5)
Query Neighborhood Hits	1031	Target Neighborhood Hits	438	Shared Neighborhood Hits	343
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
θ value	1.41672e-45 (rank : 6)	NC score	0.872490 (rank : 6)
Query Neighborhood Hits	1031	Target Neighborhood Hits	453	Shared Neighborhood Hits	351
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANK1_MOUSE
θ value	7.06379e-29 (rank : 7)	NC score	0.839473 (rank : 31)
Query Neighborhood Hits	1031	Target Neighborhood Hits	430	Shared Neighborhood Hits	310
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

RIPK4_HUMAN
θ value	3.50572e-28 (rank : 8)	NC score	0.578181 (rank : 201)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1094	Shared Neighborhood Hits	362
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANK1_HUMAN
θ value	4.57862e-28 (rank : 9)	NC score	0.840131 (rank : 30)
Query Neighborhood Hits	1031	Target Neighborhood Hits	416	Shared Neighborhood Hits	309
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK2_HUMAN
θ value	2.96777e-27 (rank : 10)	NC score	0.813809 (rank : 65)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1615	Shared Neighborhood Hits	598
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANK3_HUMAN
θ value	8.63488e-27 (rank : 11)	NC score	0.834807 (rank : 36)
Query Neighborhood Hits	1031	Target Neighborhood Hits	853	Shared Neighborhood Hits	381
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR28_MOUSE
θ value	1.47289e-26 (rank : 12)	NC score	0.846678 (rank : 26)
Query Neighborhood Hits	1031	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_HUMAN
θ value	1.92365e-26 (rank : 13)	NC score	0.845427 (rank : 28)
Query Neighborhood Hits	1031	Target Neighborhood Hits	314	Shared Neighborhood Hits	297
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

TNKS2_HUMAN
θ value	1.24688e-25 (rank : 14)	NC score	0.847226 (rank : 23)
Query Neighborhood Hits	1031	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANKK1_HUMAN
θ value	8.08199e-25 (rank : 15)	NC score	0.579871 (rank : 200)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1075	Shared Neighborhood Hits	356
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANKK1_MOUSE
θ value	8.08199e-25 (rank : 16)	NC score	0.566417 (rank : 205)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1072	Shared Neighborhood Hits	354
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR44_HUMAN
θ value	1.05554e-24 (rank : 17)	NC score	0.846727 (rank : 25)
Query Neighborhood Hits	1031	Target Neighborhood Hits	318	Shared Neighborhood Hits	298
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR50_HUMAN
θ value	1.05554e-24 (rank : 18)	NC score	0.858920 (rank : 12)
Query Neighborhood Hits	1031	Target Neighborhood Hits	361	Shared Neighborhood Hits	300
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

DAPK1_MOUSE
θ value	2.35151e-24 (rank : 19)	NC score	0.414339 (rank : 256)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1138	Shared Neighborhood Hits	360
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

INVS_HUMAN
θ value	2.35151e-24 (rank : 20)	NC score	0.849085 (rank : 18)
Query Neighborhood Hits	1031	Target Neighborhood Hits	455	Shared Neighborhood Hits	327
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

TNKS1_HUMAN
θ value	4.01107e-24 (rank : 21)	NC score	0.856055 (rank : 13)
Query Neighborhood Hits	1031	Target Neighborhood Hits	477	Shared Neighborhood Hits	372
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

INVS_MOUSE
θ value	8.93572e-24 (rank : 22)	NC score	0.846937 (rank : 24)
Query Neighborhood Hits	1031	Target Neighborhood Hits	609	Shared Neighborhood Hits	388
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

DAPK1_HUMAN
θ value	1.5242e-23 (rank : 23)	NC score	0.406181 (rank : 263)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1130	Shared Neighborhood Hits	354
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

MYPT1_MOUSE
θ value	1.99067e-23 (rank : 24)	NC score	0.825528 (rank : 45)
Query Neighborhood Hits	1031	Target Neighborhood Hits	539	Shared Neighborhood Hits	313
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

MYPT1_HUMAN
θ value	2.59989e-23 (rank : 25)	NC score	0.805105 (rank : 79)
Query Neighborhood Hits	1031	Target Neighborhood Hits	723	Shared Neighborhood Hits	318
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ANR52_HUMAN
θ value	3.39556e-23 (rank : 26)	NC score	0.838374 (rank : 33)
Query Neighborhood Hits	1031	Target Neighborhood Hits	322	Shared Neighborhood Hits	297
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	4.43474e-23 (rank : 27)	NC score	0.838746 (rank : 32)
Query Neighborhood Hits	1031	Target Neighborhood Hits	318	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

TNI3K_HUMAN
θ value	5.79196e-23 (rank : 28)	NC score	0.469641 (rank : 237)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1084	Shared Neighborhood Hits	354
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANKR6_HUMAN
θ value	7.56453e-23 (rank : 29)	NC score	0.863962 (rank : 10)
Query Neighborhood Hits	1031	Target Neighborhood Hits	439	Shared Neighborhood Hits	314
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

MIB1_HUMAN
θ value	9.87957e-23 (rank : 30)	NC score	0.815872 (rank : 58)
Query Neighborhood Hits	1031	Target Neighborhood Hits	470	Shared Neighborhood Hits	299
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	9.87957e-23 (rank : 31)	NC score	0.815560 (rank : 59)
Query Neighborhood Hits	1031	Target Neighborhood Hits	471	Shared Neighborhood Hits	300
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ANR42_HUMAN
θ value	1.09232e-21 (rank : 32)	NC score	0.853158 (rank : 16)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB10_HUMAN
θ value	1.09232e-21 (rank : 33)	NC score	0.848849 (rank : 22)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB3_MOUSE
θ value	1.42661e-21 (rank : 34)	NC score	0.849085 (rank : 19)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	290
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

TNI3K_MOUSE
θ value	2.43343e-21 (rank : 35)	NC score	0.463968 (rank : 242)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1079	Shared Neighborhood Hits	355
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

RAI14_MOUSE
θ value	7.0802e-21 (rank : 36)	NC score	0.599643 (rank : 194)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1505	Shared Neighborhood Hits	382
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ZDH17_HUMAN
θ value	7.0802e-21 (rank : 37)	NC score	0.750544 (rank : 135)
Query Neighborhood Hits	1031	Target Neighborhood Hits	334	Shared Neighborhood Hits	285
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ASB3_HUMAN
θ value	1.2077e-20 (rank : 38)	NC score	0.849032 (rank : 20)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

RAI14_HUMAN
θ value	1.2077e-20 (rank : 39)	NC score	0.630709 (rank : 190)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1367	Shared Neighborhood Hits	373
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ZDH17_MOUSE
θ value	1.2077e-20 (rank : 40)	NC score	0.746074 (rank : 138)
Query Neighborhood Hits	1031	Target Neighborhood Hits	328	Shared Neighborhood Hits	279
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANR42_MOUSE
θ value	1.5773e-20 (rank : 41)	NC score	0.849690 (rank : 17)
Query Neighborhood Hits	1031	Target Neighborhood Hits	334	Shared Neighborhood Hits	282
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB10_MOUSE
θ value	1.5773e-20 (rank : 42)	NC score	0.848872 (rank : 21)
Query Neighborhood Hits	1031	Target Neighborhood Hits	301	Shared Neighborhood Hits	285
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANR29_HUMAN
θ value	7.82807e-20 (rank : 43)	NC score	0.867573 (rank : 7)
Query Neighborhood Hits	1031	Target Neighborhood Hits	294	Shared Neighborhood Hits	284
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ASB7_MOUSE
θ value	1.33526e-19 (rank : 44)	NC score	0.853677 (rank : 14)
Query Neighborhood Hits	1031	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
θ value	1.74391e-19 (rank : 45)	NC score	0.853669 (rank : 15)
Query Neighborhood Hits	1031	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

MYPT2_HUMAN
θ value	1.74391e-19 (rank : 46)	NC score	0.809150 (rank : 69)
Query Neighborhood Hits	1031	Target Neighborhood Hits	707	Shared Neighborhood Hits	319
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PA2G6_MOUSE
θ value	1.74391e-19 (rank : 47)	NC score	0.824971 (rank : 48)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

TRPA1_HUMAN
θ value	2.97466e-19 (rank : 48)	NC score	0.824672 (rank : 51)
Query Neighborhood Hits	1031	Target Neighborhood Hits	339	Shared Neighborhood Hits	291
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

PSD10_HUMAN
θ value	3.88503e-19 (rank : 49)	NC score	0.866894 (rank : 8)
Query Neighborhood Hits	1031	Target Neighborhood Hits	301	Shared Neighborhood Hits	291
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR16_HUMAN
θ value	1.13037e-18 (rank : 50)	NC score	0.860134 (rank : 11)
Query Neighborhood Hits	1031	Target Neighborhood Hits	286	Shared Neighborhood Hits	280
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

PSD10_MOUSE
θ value	1.13037e-18 (rank : 51)	NC score	0.865168 (rank : 9)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

EHMT1_HUMAN
θ value	1.47631e-18 (rank : 52)	NC score	0.789598 (rank : 100)
Query Neighborhood Hits	1031	Target Neighborhood Hits	417	Shared Neighborhood Hits	312
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

MIB2_MOUSE
θ value	3.28887e-18 (rank : 53)	NC score	0.804098 (rank : 80)
Query Neighborhood Hits	1031	Target Neighborhood Hits	409	Shared Neighborhood Hits	289
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

TRPA1_MOUSE
θ value	5.60996e-18 (rank : 54)	NC score	0.824746 (rank : 50)
Query Neighborhood Hits	1031	Target Neighborhood Hits	343	Shared Neighborhood Hits	290
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

CTTB2_HUMAN
θ value	1.63225e-17 (rank : 55)	NC score	0.734362 (rank : 147)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1061	Shared Neighborhood Hits	382
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

MIB2_HUMAN
θ value	3.63628e-17 (rank : 56)	NC score	0.805299 (rank : 78)
Query Neighborhood Hits	1031	Target Neighborhood Hits	438	Shared Neighborhood Hits	295
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ASB15_MOUSE
θ value	4.74913e-17 (rank : 57)	NC score	0.799045 (rank : 86)
Query Neighborhood Hits	1031	Target Neighborhood Hits	292	Shared Neighborhood Hits	272
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

PP16B_MOUSE
θ value	4.74913e-17 (rank : 58)	NC score	0.806452 (rank : 74)
Query Neighborhood Hits	1031	Target Neighborhood Hits	302	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

NOTC4_HUMAN
θ value	6.20254e-17 (rank : 59)	NC score	0.455140 (rank : 246)
Query Neighborhood Hits	1031	Target Neighborhood Hits	905	Shared Neighborhood Hits	332
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

PP16B_HUMAN
θ value	1.80466e-16 (rank : 60)	NC score	0.808173 (rank : 70)
Query Neighborhood Hits	1031	Target Neighborhood Hits	307	Shared Neighborhood Hits	285
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ASB13_HUMAN
θ value	2.35696e-16 (rank : 61)	NC score	0.830415 (rank : 40)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
θ value	3.07829e-16 (rank : 62)	NC score	0.830731 (rank : 39)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

FANK1_HUMAN
θ value	3.07829e-16 (rank : 63)	NC score	0.845460 (rank : 27)
Query Neighborhood Hits	1031	Target Neighborhood Hits	326	Shared Neighborhood Hits	293
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANKS6_HUMAN
θ value	4.02038e-16 (rank : 64)	NC score	0.824384 (rank : 53)
Query Neighborhood Hits	1031	Target Neighborhood Hits	411	Shared Neighborhood Hits	329
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

OSBL1_HUMAN
θ value	4.02038e-16 (rank : 65)	NC score	0.660972 (rank : 177)
Query Neighborhood Hits	1031	Target Neighborhood Hits	368	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ASB2_MOUSE
θ value	5.25075e-16 (rank : 66)	NC score	0.824576 (rank : 52)
Query Neighborhood Hits	1031	Target Neighborhood Hits	321	Shared Neighborhood Hits	286
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

OSBL1_MOUSE
θ value	5.25075e-16 (rank : 67)	NC score	0.648575 (rank : 181)
Query Neighborhood Hits	1031	Target Neighborhood Hits	336	Shared Neighborhood Hits	281
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANKS6_MOUSE
θ value	6.85773e-16 (rank : 68)	NC score	0.825115 (rank : 47)
Query Neighborhood Hits	1031	Target Neighborhood Hits	435	Shared Neighborhood Hits	345
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

NOTC4_MOUSE
θ value	8.95645e-16 (rank : 69)	NC score	0.458845 (rank : 245)
Query Neighborhood Hits	1031	Target Neighborhood Hits	872	Shared Neighborhood Hits	319
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

EHMT2_MOUSE
θ value	1.16975e-15 (rank : 70)	NC score	0.777198 (rank : 115)
Query Neighborhood Hits	1031	Target Neighborhood Hits	750	Shared Neighborhood Hits	423
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ZDH13_MOUSE
θ value	1.52774e-15 (rank : 71)	NC score	0.736515 (rank : 144)
Query Neighborhood Hits	1031	Target Neighborhood Hits	329	Shared Neighborhood Hits	284
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

EHMT2_HUMAN
θ value	1.99529e-15 (rank : 72)	NC score	0.778664 (rank : 112)
Query Neighborhood Hits	1031	Target Neighborhood Hits	498	Shared Neighborhood Hits	326
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FANK1_MOUSE
θ value	1.99529e-15 (rank : 73)	NC score	0.843974 (rank : 29)
Query Neighborhood Hits	1031	Target Neighborhood Hits	325	Shared Neighborhood Hits	292
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANKR2_MOUSE
θ value	4.44505e-15 (rank : 74)	NC score	0.834277 (rank : 37)
Query Neighborhood Hits	1031	Target Neighborhood Hits	312	Shared Neighborhood Hits	287
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR21_HUMAN
θ value	4.44505e-15 (rank : 75)	NC score	0.712471 (rank : 154)
Query Neighborhood Hits	1031	Target Neighborhood Hits	864	Shared Neighborhood Hits	319
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR35_HUMAN
θ value	5.8054e-15 (rank : 76)	NC score	0.770616 (rank : 122)
Query Neighborhood Hits	1031	Target Neighborhood Hits	784	Shared Neighborhood Hits	316
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB9_HUMAN
θ value	5.8054e-15 (rank : 77)	NC score	0.799944 (rank : 83)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	253
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB9_MOUSE
θ value	9.90251e-15 (rank : 78)	NC score	0.790687 (rank : 98)
Query Neighborhood Hits	1031	Target Neighborhood Hits	257	Shared Neighborhood Hits	250
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB2_HUMAN
θ value	1.68911e-14 (rank : 79)	NC score	0.829959 (rank : 42)
Query Neighborhood Hits	1031	Target Neighborhood Hits	309	Shared Neighborhood Hits	287
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANKS3_HUMAN
θ value	2.20605e-14 (rank : 80)	NC score	0.812617 (rank : 67)
Query Neighborhood Hits	1031	Target Neighborhood Hits	355	Shared Neighborhood Hits	285
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR11_HUMAN
θ value	2.20605e-14 (rank : 81)	NC score	0.751548 (rank : 133)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1289	Shared Neighborhood Hits	447
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ASB15_HUMAN
θ value	2.20605e-14 (rank : 82)	NC score	0.805495 (rank : 77)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

POTE8_HUMAN
θ value	2.20605e-14 (rank : 83)	NC score	0.756240 (rank : 131)
Query Neighborhood Hits	1031	Target Neighborhood Hits	337	Shared Neighborhood Hits	283
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ANKR5_MOUSE
θ value	2.88119e-14 (rank : 84)	NC score	0.806200 (rank : 75)
Query Neighborhood Hits	1031	Target Neighborhood Hits	298	Shared Neighborhood Hits	284
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR12_HUMAN
θ value	2.88119e-14 (rank : 85)	NC score	0.705137 (rank : 158)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1081	Shared Neighborhood Hits	333
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

BCL3_HUMAN
θ value	2.88119e-14 (rank : 86)	NC score	0.827281 (rank : 43)
Query Neighborhood Hits	1031	Target Neighborhood Hits	324	Shared Neighborhood Hits	302
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

NFKB1_HUMAN
θ value	2.88119e-14 (rank : 87)	NC score	0.709391 (rank : 156)
Query Neighborhood Hits	1031	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

PP16A_MOUSE
θ value	2.88119e-14 (rank : 88)	NC score	0.813990 (rank : 64)
Query Neighborhood Hits	1031	Target Neighborhood Hits	318	Shared Neighborhood Hits	286
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

CDN2C_HUMAN
θ value	3.76295e-14 (rank : 89)	NC score	0.824765 (rank : 49)
Query Neighborhood Hits	1031	Target Neighborhood Hits	262	Shared Neighborhood Hits	260
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANFY1_MOUSE
θ value	6.41864e-14 (rank : 90)	NC score	0.743767 (rank : 139)
Query Neighborhood Hits	1031	Target Neighborhood Hits	480	Shared Neighborhood Hits	294
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKS3_MOUSE
θ value	6.41864e-14 (rank : 91)	NC score	0.814754 (rank : 61)
Query Neighborhood Hits	1031	Target Neighborhood Hits	355	Shared Neighborhood Hits	282
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB5_HUMAN
θ value	6.41864e-14 (rank : 92)	NC score	0.795868 (rank : 89)
Query Neighborhood Hits	1031	Target Neighborhood Hits	283	Shared Neighborhood Hits	269
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB5_MOUSE
θ value	6.41864e-14 (rank : 93)	NC score	0.794142 (rank : 93)
Query Neighborhood Hits	1031	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

BCL3_MOUSE
θ value	8.38298e-14 (rank : 94)	NC score	0.825139 (rank : 46)
Query Neighborhood Hits	1031	Target Neighborhood Hits	388	Shared Neighborhood Hits	322
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

POT15_HUMAN
θ value	8.38298e-14 (rank : 95)	NC score	0.711087 (rank : 155)
Query Neighborhood Hits	1031	Target Neighborhood Hits	893	Shared Neighborhood Hits	317
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ZDH13_HUMAN
θ value	8.38298e-14 (rank : 96)	NC score	0.734790 (rank : 145)
Query Neighborhood Hits	1031	Target Neighborhood Hits	322	Shared Neighborhood Hits	280
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ASB11_HUMAN
θ value	1.42992e-13 (rank : 97)	NC score	0.794045 (rank : 94)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANKR2_HUMAN
θ value	1.86753e-13 (rank : 98)	NC score	0.831125 (rank : 38)
Query Neighborhood Hits	1031	Target Neighborhood Hits	321	Shared Neighborhood Hits	290
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR15_HUMAN
θ value	1.86753e-13 (rank : 99)	NC score	0.731569 (rank : 148)
Query Neighborhood Hits	1031	Target Neighborhood Hits	478	Shared Neighborhood Hits	295
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

CDN2C_MOUSE
θ value	1.86753e-13 (rank : 100)	NC score	0.824142 (rank : 54)
Query Neighborhood Hits	1031	Target Neighborhood Hits	270	Shared Neighborhood Hits	266
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANFY1_HUMAN
θ value	2.43908e-13 (rank : 101)	NC score	0.742554 (rank : 140)
Query Neighborhood Hits	1031	Target Neighborhood Hits	480	Shared Neighborhood Hits	289
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKR5_HUMAN
θ value	3.18553e-13 (rank : 102)	NC score	0.801864 (rank : 82)
Query Neighborhood Hits	1031	Target Neighborhood Hits	297	Shared Neighborhood Hits	282
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB14_MOUSE
θ value	5.43371e-13 (rank : 103)	NC score	0.795822 (rank : 90)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

NOTC3_HUMAN
θ value	5.43371e-13 (rank : 104)	NC score	0.416262 (rank : 254)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1062	Shared Neighborhood Hits	396
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ANR39_HUMAN
θ value	7.09661e-13 (rank : 105)	NC score	0.836612 (rank : 34)
Query Neighborhood Hits	1031	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

NOTC3_MOUSE
θ value	9.26847e-13 (rank : 106)	NC score	0.416283 (rank : 253)
Query Neighborhood Hits	1031	Target Neighborhood Hits	975	Shared Neighborhood Hits	358
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ILK_MOUSE
θ value	1.58096e-12 (rank : 107)	NC score	0.534904 (rank : 216)
Query Neighborhood Hits	1031	Target Neighborhood Hits	858	Shared Neighborhood Hits	327
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

RN5A_MOUSE
θ value	1.58096e-12 (rank : 108)	NC score	0.738689 (rank : 142)
Query Neighborhood Hits	1031	Target Neighborhood Hits	899	Shared Neighborhood Hits	335
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

AN30A_HUMAN
θ value	2.0648e-12 (rank : 109)	NC score	0.573005 (rank : 202)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1119	Shared Neighborhood Hits	348
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

BARD1_HUMAN
θ value	2.0648e-12 (rank : 110)	NC score	0.777790 (rank : 113)
Query Neighborhood Hits	1031	Target Neighborhood Hits	427	Shared Neighborhood Hits	293
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	2.0648e-12 (rank : 111)	NC score	0.775193 (rank : 118)
Query Neighborhood Hits	1031	Target Neighborhood Hits	411	Shared Neighborhood Hits	285
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

NFKB1_MOUSE
θ value	2.0648e-12 (rank : 112)	NC score	0.707924 (rank : 157)
Query Neighborhood Hits	1031	Target Neighborhood Hits	300	Shared Neighborhood Hits	273
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ASB16_MOUSE
θ value	2.69671e-12 (rank : 113)	NC score	0.809679 (rank : 68)
Query Neighborhood Hits	1031	Target Neighborhood Hits	306	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

IKBA_HUMAN
θ value	2.69671e-12 (rank : 114)	NC score	0.799261 (rank : 85)
Query Neighborhood Hits	1031	Target Neighborhood Hits	280	Shared Neighborhood Hits	275
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ILK1_HUMAN
θ value	2.69671e-12 (rank : 115)	NC score	0.535700 (rank : 215)
Query Neighborhood Hits	1031	Target Neighborhood Hits	857	Shared Neighborhood Hits	327
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	2.69671e-12 (rank : 116)	NC score	0.552813 (rank : 212)
Query Neighborhood Hits	1031	Target Neighborhood Hits	848	Shared Neighborhood Hits	327
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

PP16A_HUMAN
θ value	2.69671e-12 (rank : 117)	NC score	0.807431 (rank : 73)
Query Neighborhood Hits	1031	Target Neighborhood Hits	340	Shared Neighborhood Hits	297
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR47_MOUSE
θ value	3.52202e-12 (rank : 118)	NC score	0.727878 (rank : 150)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	273
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR18_HUMAN
θ value	4.59992e-12 (rank : 119)	NC score	0.600202 (rank : 193)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1106	Shared Neighborhood Hits	320
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR39_MOUSE
θ value	4.59992e-12 (rank : 120)	NC score	0.835301 (rank : 35)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

NOTC1_HUMAN
θ value	4.59992e-12 (rank : 121)	NC score	0.408462 (rank : 262)
Query Neighborhood Hits	1031	Target Neighborhood Hits	906	Shared Neighborhood Hits	320
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KRIT1_HUMAN
θ value	7.84624e-12 (rank : 122)	NC score	0.683309 (rank : 171)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

POT14_HUMAN
θ value	1.02475e-11 (rank : 123)	NC score	0.697617 (rank : 165)
Query Neighborhood Hits	1031	Target Neighborhood Hits	403	Shared Neighborhood Hits	280
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ASZ1_HUMAN
θ value	1.33837e-11 (rank : 124)	NC score	0.799386 (rank : 84)
Query Neighborhood Hits	1031	Target Neighborhood Hits	341	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

PA2G6_HUMAN
θ value	1.74796e-11 (rank : 125)	NC score	0.805501 (rank : 76)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANRA2_HUMAN
θ value	2.28291e-11 (rank : 126)	NC score	0.795421 (rank : 91)
Query Neighborhood Hits	1031	Target Neighborhood Hits	288	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

CDN2D_HUMAN
θ value	2.28291e-11 (rank : 127)	NC score	0.807492 (rank : 72)
Query Neighborhood Hits	1031	Target Neighborhood Hits	268	Shared Neighborhood Hits	265
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

NOTC2_HUMAN
θ value	2.28291e-11 (rank : 128)	NC score	0.414543 (rank : 255)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1113	Shared Neighborhood Hits	446
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

AN36B_HUMAN
θ value	2.98157e-11 (rank : 129)	NC score	0.779943 (rank : 111)
Query Neighborhood Hits	1031	Target Neighborhood Hits	294	Shared Neighborhood Hits	280
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANKR1_HUMAN
θ value	2.98157e-11 (rank : 130)	NC score	0.822687 (rank : 55)
Query Neighborhood Hits	1031	Target Neighborhood Hits	308	Shared Neighborhood Hits	280
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANR23_MOUSE
θ value	2.98157e-11 (rank : 131)	NC score	0.830113 (rank : 41)
Query Neighborhood Hits	1031	Target Neighborhood Hits	296	Shared Neighborhood Hits	285
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

IKBA_MOUSE
θ value	2.98157e-11 (rank : 132)	NC score	0.787633 (rank : 102)
Query Neighborhood Hits	1031	Target Neighborhood Hits	283	Shared Neighborhood Hits	275
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

KRIT1_MOUSE
θ value	2.98157e-11 (rank : 133)	NC score	0.692954 (rank : 167)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	230
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

MUC1_HUMAN
θ value	2.98157e-11 (rank : 134)	NC score	0.174380 (rank : 302)
Query Neighborhood Hits	1031	Target Neighborhood Hits	975	Shared Neighborhood Hits	346
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NOTC2_MOUSE
θ value	2.98157e-11 (rank : 135)	NC score	0.410106 (rank : 259)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1069	Shared Neighborhood Hits	414
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ANKR1_MOUSE
θ value	3.89403e-11 (rank : 136)	NC score	0.820355 (rank : 56)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	283
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB11_MOUSE
θ value	3.89403e-11 (rank : 137)	NC score	0.790814 (rank : 97)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	256
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

RN5A_HUMAN
θ value	3.89403e-11 (rank : 138)	NC score	0.781407 (rank : 109)
Query Neighborhood Hits	1031	Target Neighborhood Hits	608	Shared Neighborhood Hits	308
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

UACA_HUMAN
θ value	6.64225e-11 (rank : 139)	NC score	0.487983 (rank : 233)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1622	Shared Neighborhood Hits	366
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

NFKB2_HUMAN
θ value	8.67504e-11 (rank : 140)	NC score	0.699793 (rank : 164)
Query Neighborhood Hits	1031	Target Neighborhood Hits	325	Shared Neighborhood Hits	280
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANRA2_MOUSE
θ value	1.133e-10 (rank : 141)	NC score	0.792309 (rank : 95)
Query Neighborhood Hits	1031	Target Neighborhood Hits	287	Shared Neighborhood Hits	271
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR23_HUMAN
θ value	1.47974e-10 (rank : 142)	NC score	0.825972 (rank : 44)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	285
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ASB16_HUMAN
θ value	1.9326e-10 (rank : 143)	NC score	0.798839 (rank : 87)
Query Neighborhood Hits	1031	Target Neighborhood Hits	286	Shared Neighborhood Hits	271
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

NFKB2_MOUSE
θ value	1.9326e-10 (rank : 144)	NC score	0.684007 (rank : 170)
Query Neighborhood Hits	1031	Target Neighborhood Hits	326	Shared Neighborhood Hits	279
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

UACA_MOUSE
θ value	2.52405e-10 (rank : 145)	NC score	0.462495 (rank : 243)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1620	Shared Neighborhood Hits	368
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ANR10_MOUSE
θ value	3.29651e-10 (rank : 146)	NC score	0.786588 (rank : 103)
Query Neighborhood Hits	1031	Target Neighborhood Hits	273	Shared Neighborhood Hits	263
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

NOTC1_MOUSE
θ value	3.29651e-10 (rank : 147)	NC score	0.350428 (rank : 267)
Query Neighborhood Hits	1031	Target Neighborhood Hits	916	Shared Neighborhood Hits	312
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

GABP2_MOUSE
θ value	4.30538e-10 (rank : 148)	NC score	0.816759 (rank : 57)
Query Neighborhood Hits	1031	Target Neighborhood Hits	429	Shared Neighborhood Hits	290
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANR25_HUMAN
θ value	5.62301e-10 (rank : 149)	NC score	0.687442 (rank : 168)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	283
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR38_HUMAN
θ value	5.62301e-10 (rank : 150)	NC score	0.670791 (rank : 176)
Query Neighborhood Hits	1031	Target Neighborhood Hits	443	Shared Neighborhood Hits	269
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

GABP2_HUMAN
θ value	5.62301e-10 (rank : 151)	NC score	0.814824 (rank : 60)
Query Neighborhood Hits	1031	Target Neighborhood Hits	454	Shared Neighborhood Hits	289
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP3_MOUSE
θ value	7.34386e-10 (rank : 152)	NC score	0.814464 (rank : 63)
Query Neighborhood Hits	1031	Target Neighborhood Hits	330	Shared Neighborhood Hits	279
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANR38_MOUSE
θ value	9.59137e-10 (rank : 153)	NC score	0.647407 (rank : 183)
Query Neighborhood Hits	1031	Target Neighborhood Hits	512	Shared Neighborhood Hits	270
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

IKBB_HUMAN
θ value	9.59137e-10 (rank : 154)	NC score	0.765240 (rank : 127)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBB_MOUSE
θ value	9.59137e-10 (rank : 155)	NC score	0.767833 (rank : 125)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

USH1G_HUMAN
θ value	1.25267e-09 (rank : 156)	NC score	0.751657 (rank : 132)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	262
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	1.25267e-09 (rank : 157)	NC score	0.751488 (rank : 134)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANR19_HUMAN
θ value	1.63604e-09 (rank : 158)	NC score	0.748015 (rank : 136)
Query Neighborhood Hits	1031	Target Neighborhood Hits	276	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR32_HUMAN
θ value	1.63604e-09 (rank : 159)	NC score	0.761193 (rank : 128)
Query Neighborhood Hits	1031	Target Neighborhood Hits	270	Shared Neighborhood Hits	257
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

IKBE_MOUSE
θ value	1.63604e-09 (rank : 160)	NC score	0.788507 (rank : 101)
Query Neighborhood Hits	1031	Target Neighborhood Hits	308	Shared Neighborhood Hits	279
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANR25_MOUSE
θ value	2.13673e-09 (rank : 161)	NC score	0.678220 (rank : 175)
Query Neighborhood Hits	1031	Target Neighborhood Hits	398	Shared Neighborhood Hits	300
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR47_HUMAN
θ value	3.64472e-09 (rank : 162)	NC score	0.704793 (rank : 159)
Query Neighborhood Hits	1031	Target Neighborhood Hits	369	Shared Neighborhood Hits	271
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

IKBE_HUMAN
θ value	3.64472e-09 (rank : 163)	NC score	0.770936 (rank : 121)
Query Neighborhood Hits	1031	Target Neighborhood Hits	288	Shared Neighborhood Hits	274
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

SHAN1_HUMAN
θ value	3.64472e-09 (rank : 164)	NC score	0.734368 (rank : 146)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1041	Shared Neighborhood Hits	515
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

CDN2D_MOUSE
θ value	1.38499e-08 (rank : 165)	NC score	0.796537 (rank : 88)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	265
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

EPHA1_MOUSE
θ value	1.38499e-08 (rank : 166)	NC score	0.109461 (rank : 381)
Query Neighborhood Hits	1031	Target Neighborhood Hits	958	Shared Neighborhood Hits	112
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA5_HUMAN
θ value	1.38499e-08 (rank : 167)	NC score	0.112304 (rank : 372)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	119
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

OSTF1_MOUSE
θ value	1.38499e-08 (rank : 168)	NC score	0.647785 (rank : 182)
Query Neighborhood Hits	1031	Target Neighborhood Hits	467	Shared Neighborhood Hits	298
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ANR10_HUMAN
θ value	1.80886e-08 (rank : 169)	NC score	0.786022 (rank : 106)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

NFH_MOUSE
θ value	1.80886e-08 (rank : 170)	NC score	0.110385 (rank : 377)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2247	Shared Neighborhood Hits	436
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

EPHA1_HUMAN
θ value	2.36244e-08 (rank : 171)	NC score	0.109314 (rank : 382)
Query Neighborhood Hits	1031	Target Neighborhood Hits	997	Shared Neighborhood Hits	119
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

ANKR7_HUMAN
θ value	3.08544e-08 (rank : 172)	NC score	0.791709 (rank : 96)
Query Neighborhood Hits	1031	Target Neighborhood Hits	286	Shared Neighborhood Hits	279
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ASB12_HUMAN
θ value	3.08544e-08 (rank : 173)	NC score	0.769623 (rank : 124)
Query Neighborhood Hits	1031	Target Neighborhood Hits	263	Shared Neighborhood Hits	262
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB4_HUMAN
θ value	3.08544e-08 (rank : 174)	NC score	0.777612 (rank : 114)
Query Neighborhood Hits	1031	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

EPHA2_HUMAN
θ value	3.08544e-08 (rank : 175)	NC score	0.108196 (rank : 394)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1021	Shared Neighborhood Hits	110
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

RFXK_HUMAN
θ value	3.08544e-08 (rank : 176)	NC score	0.786393 (rank : 104)
Query Neighborhood Hits	1031	Target Neighborhood Hits	282	Shared Neighborhood Hits	268
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ASB12_MOUSE
θ value	4.0297e-08 (rank : 177)	NC score	0.774223 (rank : 119)
Query Neighborhood Hits	1031	Target Neighborhood Hits	261	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASZ1_MOUSE
θ value	4.0297e-08 (rank : 178)	NC score	0.795197 (rank : 92)
Query Neighborhood Hits	1031	Target Neighborhood Hits	319	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ABTB2_MOUSE
θ value	5.26297e-08 (rank : 179)	NC score	0.560070 (rank : 207)
Query Neighborhood Hits	1031	Target Neighborhood Hits	414	Shared Neighborhood Hits	234
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR26_MOUSE
θ value	5.26297e-08 (rank : 180)	NC score	0.443356 (rank : 249)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1554	Shared Neighborhood Hits	362
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB4_MOUSE
θ value	5.26297e-08 (rank : 181)	NC score	0.776984 (rank : 116)
Query Neighborhood Hits	1031	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

A20A2_HUMAN
θ value	6.87365e-08 (rank : 182)	NC score	0.635662 (rank : 187)
Query Neighborhood Hits	1031	Target Neighborhood Hits	716	Shared Neighborhood Hits	302
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANR49_MOUSE
θ value	6.87365e-08 (rank : 183)	NC score	0.807788 (rank : 71)
Query Neighborhood Hits	1031	Target Neighborhood Hits	285	Shared Neighborhood Hits	272
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ACBD6_MOUSE
θ value	8.97725e-08 (rank : 184)	NC score	0.771663 (rank : 120)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	284
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKY2_MOUSE
θ value	8.97725e-08 (rank : 185)	NC score	0.703959 (rank : 160)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	259
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

EPHA2_MOUSE
θ value	8.97725e-08 (rank : 186)	NC score	0.108158 (rank : 396)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1020	Shared Neighborhood Hits	111
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

OSTF1_HUMAN
θ value	8.97725e-08 (rank : 187)	NC score	0.630557 (rank : 191)
Query Neighborhood Hits	1031	Target Neighborhood Hits	466	Shared Neighborhood Hits	296
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

A20A1_HUMAN
θ value	1.17247e-07 (rank : 188)	NC score	0.634705 (rank : 188)
Query Neighborhood Hits	1031	Target Neighborhood Hits	698	Shared Neighborhood Hits	293
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A3_HUMAN
θ value	1.53129e-07 (rank : 189)	NC score	0.636178 (rank : 186)
Query Neighborhood Hits	1031	Target Neighborhood Hits	692	Shared Neighborhood Hits	297
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	1.53129e-07 (rank : 190)	NC score	0.631632 (rank : 189)
Query Neighborhood Hits	1031	Target Neighborhood Hits	710	Shared Neighborhood Hits	298
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ACBD6_HUMAN
θ value	1.53129e-07 (rank : 191)	NC score	0.767515 (rank : 126)
Query Neighborhood Hits	1031	Target Neighborhood Hits	304	Shared Neighborhood Hits	284
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ASB8_MOUSE
θ value	1.53129e-07 (rank : 192)	NC score	0.814599 (rank : 62)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	281
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

BCOR_MOUSE
θ value	1.53129e-07 (rank : 193)	NC score	0.701236 (rank : 162)
Query Neighborhood Hits	1031	Target Neighborhood Hits	521	Shared Neighborhood Hits	336
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

EPHB2_HUMAN
θ value	1.53129e-07 (rank : 194)	NC score	0.108416 (rank : 391)
Query Neighborhood Hits	1031	Target Neighborhood Hits	983	Shared Neighborhood Hits	111
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

POT22_HUMAN
θ value	1.53129e-07 (rank : 195)	NC score	0.657969 (rank : 179)
Query Neighborhood Hits	1031	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ABTB2_HUMAN
θ value	1.99992e-07 (rank : 196)	NC score	0.571809 (rank : 203)
Query Neighborhood Hits	1031	Target Neighborhood Hits	391	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR26_HUMAN
θ value	1.99992e-07 (rank : 197)	NC score	0.423722 (rank : 252)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1614	Shared Neighborhood Hits	364
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR32_MOUSE
θ value	1.99992e-07 (rank : 198)	NC score	0.746950 (rank : 137)
Query Neighborhood Hits	1031	Target Neighborhood Hits	285	Shared Neighborhood Hits	258
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ASB8_HUMAN
θ value	1.99992e-07 (rank : 199)	NC score	0.813782 (rank : 66)
Query Neighborhood Hits	1031	Target Neighborhood Hits	294	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

EPHA7_HUMAN
θ value	2.61198e-07 (rank : 200)	NC score	0.109903 (rank : 378)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1053	Shared Neighborhood Hits	115
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

ANKY2_HUMAN
θ value	3.41135e-07 (rank : 201)	NC score	0.724938 (rank : 152)
Query Neighborhood Hits	1031	Target Neighborhood Hits	306	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR46_MOUSE
θ value	3.41135e-07 (rank : 202)	NC score	0.780572 (rank : 110)
Query Neighborhood Hits	1031	Target Neighborhood Hits	274	Shared Neighborhood Hits	269
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

BCOR_HUMAN
θ value	3.41135e-07 (rank : 203)	NC score	0.696375 (rank : 166)
Query Neighborhood Hits	1031	Target Neighborhood Hits	609	Shared Neighborhood Hits	370
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

HECD1_HUMAN
θ value	3.41135e-07 (rank : 204)	NC score	0.587973 (rank : 199)
Query Neighborhood Hits	1031	Target Neighborhood Hits	371	Shared Neighborhood Hits	277
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

MPP8_HUMAN
θ value	4.45536e-07 (rank : 205)	NC score	0.649760 (rank : 180)
Query Neighborhood Hits	1031	Target Neighborhood Hits	948	Shared Neighborhood Hits	308
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

SON_HUMAN
θ value	4.45536e-07 (rank : 206)	NC score	0.159820 (rank : 312)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1568	Shared Neighborhood Hits	447
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ASPP2_HUMAN
θ value	5.81887e-07 (rank : 207)	NC score	0.567524 (rank : 204)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1156	Shared Neighborhood Hits	432
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

EPHA5_MOUSE
θ value	5.81887e-07 (rank : 208)	NC score	0.101831 (rank : 426)
Query Neighborhood Hits	1031	Target Neighborhood Hits	950	Shared Neighborhood Hits	105
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHA7_MOUSE
θ value	5.81887e-07 (rank : 209)	NC score	0.108808 (rank : 387)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1025	Shared Neighborhood Hits	109
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

ANR33_MOUSE
θ value	7.59969e-07 (rank : 210)	NC score	0.683198 (rank : 172)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	223
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANS4B_HUMAN
θ value	7.59969e-07 (rank : 211)	NC score	0.740438 (rank : 141)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	262
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

RGS3_MOUSE
θ value	7.59969e-07 (rank : 212)	NC score	0.144650 (rank : 324)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1621	Shared Neighborhood Hits	439
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RFXK_MOUSE
θ value	9.92553e-07 (rank : 213)	NC score	0.769895 (rank : 123)
Query Neighborhood Hits	1031	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

AN36A_HUMAN
θ value	1.29631e-06 (rank : 214)	NC score	0.737370 (rank : 143)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	268
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ASB1_MOUSE
θ value	1.29631e-06 (rank : 215)	NC score	0.760198 (rank : 130)
Query Neighborhood Hits	1031	Target Neighborhood Hits	292	Shared Neighborhood Hits	270
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

MAST4_HUMAN
θ value	1.29631e-06 (rank : 216)	NC score	0.066569 (rank : 613)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1804	Shared Neighborhood Hits	362
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ANS4B_MOUSE
θ value	1.69304e-06 (rank : 217)	NC score	0.727455 (rank : 151)
Query Neighborhood Hits	1031	Target Neighborhood Hits	294	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

PRRT3_HUMAN
θ value	2.21117e-06 (rank : 218)	NC score	0.183280 (rank : 298)
Query Neighborhood Hits	1031	Target Neighborhood Hits	998	Shared Neighborhood Hits	381
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

AN13B_HUMAN
θ value	2.88788e-06 (rank : 219)	NC score	0.524925 (rank : 222)
Query Neighborhood Hits	1031	Target Neighborhood Hits	265	Shared Neighborhood Hits	253
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	2.88788e-06 (rank : 220)	NC score	0.525794 (rank : 221)
Query Neighborhood Hits	1031	Target Neighborhood Hits	276	Shared Neighborhood Hits	255
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANR46_HUMAN
θ value	2.88788e-06 (rank : 221)	NC score	0.785007 (rank : 108)
Query Neighborhood Hits	1031	Target Neighborhood Hits	281	Shared Neighborhood Hits	276
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR49_HUMAN
θ value	3.77169e-06 (rank : 222)	NC score	0.802395 (rank : 81)
Query Neighborhood Hits	1031	Target Neighborhood Hits	282	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

K1802_MOUSE
θ value	3.77169e-06 (rank : 223)	NC score	0.125845 (rank : 345)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1596	Shared Neighborhood Hits	389
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RGS3_HUMAN
θ value	4.92598e-06 (rank : 224)	NC score	0.110678 (rank : 375)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1375	Shared Neighborhood Hits	373
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ANR37_MOUSE
θ value	6.43352e-06 (rank : 225)	NC score	0.701211 (rank : 163)
Query Neighborhood Hits	1031	Target Neighborhood Hits	237	Shared Neighborhood Hits	234
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

CT012_MOUSE
θ value	6.43352e-06 (rank : 226)	NC score	0.469194 (rank : 238)
Query Neighborhood Hits	1031	Target Neighborhood Hits	229	Shared Neighborhood Hits	182
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

DGKI_HUMAN
θ value	6.43352e-06 (rank : 227)	NC score	0.350207 (rank : 268)
Query Neighborhood Hits	1031	Target Neighborhood Hits	609	Shared Neighborhood Hits	226
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

MDC1_MOUSE
θ value	6.43352e-06 (rank : 228)	NC score	0.152714 (rank : 318)
Query Neighborhood Hits	1031	Target Neighborhood Hits	998	Shared Neighborhood Hits	316
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NACAM_MOUSE
θ value	6.43352e-06 (rank : 229)	NC score	0.186702 (rank : 297)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1866	Shared Neighborhood Hits	501
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

EPHB2_MOUSE
θ value	8.40245e-06 (rank : 230)	NC score	0.106768 (rank : 406)
Query Neighborhood Hits	1031	Target Neighborhood Hits	982	Shared Neighborhood Hits	111
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

OGFR_HUMAN
θ value	1.09739e-05 (rank : 231)	NC score	0.171743 (rank : 305)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1582	Shared Neighborhood Hits	455
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ASB1_HUMAN
θ value	1.43324e-05 (rank : 232)	NC score	0.760596 (rank : 129)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CT086_HUMAN
θ value	1.43324e-05 (rank : 233)	NC score	0.786251 (rank : 105)
Query Neighborhood Hits	1031	Target Neighborhood Hits	277	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

MLL3_HUMAN
θ value	1.43324e-05 (rank : 234)	NC score	0.142817 (rank : 326)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1644	Shared Neighborhood Hits	403
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RSNL2_HUMAN
θ value	1.43324e-05 (rank : 235)	NC score	0.266049 (rank : 282)
Query Neighborhood Hits	1031	Target Neighborhood Hits	136	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

ANR37_HUMAN
θ value	1.87187e-05 (rank : 236)	NC score	0.717756 (rank : 153)
Query Neighborhood Hits	1031	Target Neighborhood Hits	247	Shared Neighborhood Hits	244
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ASPP1_MOUSE
θ value	1.87187e-05 (rank : 237)	NC score	0.557684 (rank : 208)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1244	Shared Neighborhood Hits	520
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

EPHB1_HUMAN
θ value	1.87187e-05 (rank : 238)	NC score	0.105600 (rank : 409)
Query Neighborhood Hits	1031	Target Neighborhood Hits	988	Shared Neighborhood Hits	112
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHB4_HUMAN
θ value	1.87187e-05 (rank : 239)	NC score	0.109108 (rank : 383)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1056	Shared Neighborhood Hits	121
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB4_MOUSE
θ value	1.87187e-05 (rank : 240)	NC score	0.107723 (rank : 398)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1013	Shared Neighborhood Hits	118
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

TRPV5_MOUSE
θ value	1.87187e-05 (rank : 241)	NC score	0.484844 (rank : 234)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	246
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

AN13A_HUMAN
θ value	2.44474e-05 (rank : 242)	NC score	0.461963 (rank : 244)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANR22_HUMAN
θ value	2.44474e-05 (rank : 243)	NC score	0.776603 (rank : 117)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	240
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ASPP1_HUMAN
θ value	3.19293e-05 (rank : 244)	NC score	0.556450 (rank : 210)
Query Neighborhood Hits	1031	Target Neighborhood Hits	956	Shared Neighborhood Hits	395
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CENB2_HUMAN
θ value	3.19293e-05 (rank : 245)	NC score	0.518848 (rank : 224)
Query Neighborhood Hits	1031	Target Neighborhood Hits	425	Shared Neighborhood Hits	265
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

MARK2_HUMAN
θ value	3.19293e-05 (rank : 246)	NC score	0.046160 (rank : 931)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1056	Shared Neighborhood Hits	144
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

TRPV6_MOUSE
θ value	3.19293e-05 (rank : 247)	NC score	0.530864 (rank : 220)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TXND2_HUMAN
θ value	3.19293e-05 (rank : 248)	NC score	0.107537 (rank : 400)
Query Neighborhood Hits	1031	Target Neighborhood Hits	793	Shared Neighborhood Hits	194
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ANR41_HUMAN
θ value	4.1701e-05 (rank : 249)	NC score	0.729994 (rank : 149)
Query Neighborhood Hits	1031	Target Neighborhood Hits	332	Shared Neighborhood Hits	273
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

EPHB3_HUMAN
θ value	4.1701e-05 (rank : 250)	NC score	0.108812 (rank : 386)
Query Neighborhood Hits	1031	Target Neighborhood Hits	996	Shared Neighborhood Hits	113
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB3_MOUSE
θ value	4.1701e-05 (rank : 251)	NC score	0.107562 (rank : 399)
Query Neighborhood Hits	1031	Target Neighborhood Hits	996	Shared Neighborhood Hits	107
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

GIT1_HUMAN
θ value	4.1701e-05 (rank : 252)	NC score	0.481576 (rank : 236)
Query Neighborhood Hits	1031	Target Neighborhood Hits	336	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	4.1701e-05 (rank : 253)	NC score	0.482535 (rank : 235)
Query Neighborhood Hits	1031	Target Neighborhood Hits	341	Shared Neighborhood Hits	254
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

CD2A1_HUMAN
θ value	5.44631e-05 (rank : 254)	NC score	0.609898 (rank : 192)
Query Neighborhood Hits	1031	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CD2A1_MOUSE
θ value	5.44631e-05 (rank : 255)	NC score	0.680927 (rank : 173)
Query Neighborhood Hits	1031	Target Neighborhood Hits	206	Shared Neighborhood Hits	203
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

DDEF2_HUMAN
θ value	5.44631e-05 (rank : 256)	NC score	0.413577 (rank : 257)
Query Neighborhood Hits	1031	Target Neighborhood Hits	599	Shared Neighborhood Hits	338
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	5.44631e-05 (rank : 257)	NC score	0.409927 (rank : 260)
Query Neighborhood Hits	1031	Target Neighborhood Hits	625	Shared Neighborhood Hits	351
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_MOUSE
θ value	7.1131e-05 (rank : 258)	NC score	0.467330 (rank : 239)
Query Neighborhood Hits	1031	Target Neighborhood Hits	324	Shared Neighborhood Hits	260
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

NCOA6_MOUSE
θ value	7.1131e-05 (rank : 259)	NC score	0.160050 (rank : 311)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1076	Shared Neighborhood Hits	368
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MDC1_HUMAN
θ value	9.29e-05 (rank : 260)	NC score	0.165407 (rank : 308)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1446	Shared Neighborhood Hits	368
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NCOA6_HUMAN
θ value	9.29e-05 (rank : 261)	NC score	0.173201 (rank : 304)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1202	Shared Neighborhood Hits	407
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

EPHA4_MOUSE
θ value	0.000121331 (rank : 262)	NC score	0.103909 (rank : 415)
Query Neighborhood Hits	1031	Target Neighborhood Hits	982	Shared Neighborhood Hits	106
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

GIT2_HUMAN
θ value	0.000121331 (rank : 263)	NC score	0.464823 (rank : 240)
Query Neighborhood Hits	1031	Target Neighborhood Hits	381	Shared Neighborhood Hits	261
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

PCLO_MOUSE
θ value	0.000121331 (rank : 264)	NC score	0.141660 (rank : 327)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2275	Shared Neighborhood Hits	522
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SC24C_HUMAN
θ value	0.000121331 (rank : 265)	NC score	0.104491 (rank : 413)
Query Neighborhood Hits	1031	Target Neighborhood Hits	662	Shared Neighborhood Hits	266
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ANR33_HUMAN
θ value	0.000158464 (rank : 266)	NC score	0.659729 (rank : 178)
Query Neighborhood Hits	1031	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

MTPN_MOUSE
θ value	0.000158464 (rank : 267)	NC score	0.790472 (rank : 99)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

AN13A_MOUSE
θ value	0.00020696 (rank : 268)	NC score	0.438421 (rank : 250)
Query Neighborhood Hits	1031	Target Neighborhood Hits	226	Shared Neighborhood Hits	214
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

DDEF1_MOUSE
θ value	0.00020696 (rank : 269)	NC score	0.328369 (rank : 274)
Query Neighborhood Hits	1031	Target Neighborhood Hits	592	Shared Neighborhood Hits	306
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

EPHA4_HUMAN
θ value	0.00020696 (rank : 270)	NC score	0.103615 (rank : 418)
Query Neighborhood Hits	1031	Target Neighborhood Hits	975	Shared Neighborhood Hits	106
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

GIT2_MOUSE
θ value	0.00020696 (rank : 271)	NC score	0.499182 (rank : 232)
Query Neighborhood Hits	1031	Target Neighborhood Hits	323	Shared Neighborhood Hits	263
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

MLL3_MOUSE
θ value	0.00020696 (rank : 272)	NC score	0.133504 (rank : 339)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1399	Shared Neighborhood Hits	357
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CENB5_HUMAN
θ value	0.000270298 (rank : 273)	NC score	0.532086 (rank : 218)
Query Neighborhood Hits	1031	Target Neighborhood Hits	395	Shared Neighborhood Hits	272
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

LARP4_MOUSE
θ value	0.000270298 (rank : 274)	NC score	0.089728 (rank : 460)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

PCLO_HUMAN
θ value	0.000270298 (rank : 275)	NC score	0.144288 (rank : 325)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2046	Shared Neighborhood Hits	482
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SNCAP_HUMAN
θ value	0.000270298 (rank : 276)	NC score	0.701580 (rank : 161)
Query Neighborhood Hits	1031	Target Neighborhood Hits	313	Shared Neighborhood Hits	255
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANR45_MOUSE
θ value	0.00035302 (rank : 277)	NC score	0.598083 (rank : 195)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

LIPB2_HUMAN
θ value	0.00035302 (rank : 278)	NC score	0.066675 (rank : 610)
Query Neighborhood Hits	1031	Target Neighborhood Hits	599	Shared Neighborhood Hits	74
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

RTP3_MOUSE
θ value	0.00035302 (rank : 279)	NC score	0.114115 (rank : 365)
Query Neighborhood Hits	1031	Target Neighborhood Hits	374	Shared Neighborhood Hits	161
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

MTPN_HUMAN
θ value	0.000461057 (rank : 280)	NC score	0.785797 (rank : 107)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

RSNL2_MOUSE
θ value	0.000461057 (rank : 281)	NC score	0.227006 (rank : 287)
Query Neighborhood Hits	1031	Target Neighborhood Hits	129	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

CT012_HUMAN
θ value	0.000602161 (rank : 282)	NC score	0.427724 (rank : 251)
Query Neighborhood Hits	1031	Target Neighborhood Hits	205	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DDFL1_HUMAN
θ value	0.000602161 (rank : 283)	NC score	0.376590 (rank : 264)
Query Neighborhood Hits	1031	Target Neighborhood Hits	353	Shared Neighborhood Hits	252
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

TEX14_MOUSE
θ value	0.000602161 (rank : 284)	NC score	0.409352 (rank : 261)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1333	Shared Neighborhood Hits	349
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

EPHA6_HUMAN
θ value	0.000786445 (rank : 285)	NC score	0.110523 (rank : 376)
Query Neighborhood Hits	1031	Target Neighborhood Hits	959	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA8_MOUSE
θ value	0.000786445 (rank : 286)	NC score	0.107003 (rank : 404)
Query Neighborhood Hits	1031	Target Neighborhood Hits	969	Shared Neighborhood Hits	104
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

GLSL_MOUSE
θ value	0.000786445 (rank : 287)	NC score	0.503683 (rank : 230)
Query Neighborhood Hits	1031	Target Neighborhood Hits	212	Shared Neighborhood Hits	202
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ATN1_HUMAN
θ value	0.00102713 (rank : 288)	NC score	0.137167 (rank : 334)
Query Neighborhood Hits	1031	Target Neighborhood Hits	676	Shared Neighborhood Hits	228
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

FA47B_HUMAN
θ value	0.00102713 (rank : 289)	NC score	0.117867 (rank : 357)
Query Neighborhood Hits	1031	Target Neighborhood Hits	431	Shared Neighborhood Hits	185
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

BCL9_HUMAN
θ value	0.00134147 (rank : 290)	NC score	0.148804 (rank : 322)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1008	Shared Neighborhood Hits	358
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

EPHA8_HUMAN
θ value	0.00134147 (rank : 291)	NC score	0.104998 (rank : 411)
Query Neighborhood Hits	1031	Target Neighborhood Hits	956	Shared Neighborhood Hits	103
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

GLSL_HUMAN
θ value	0.00134147 (rank : 292)	NC score	0.507425 (rank : 229)
Query Neighborhood Hits	1031	Target Neighborhood Hits	211	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

MAGE1_HUMAN
θ value	0.00134147 (rank : 293)	NC score	0.137696 (rank : 332)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1389	Shared Neighborhood Hits	420
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SARM1_MOUSE
θ value	0.00134147 (rank : 294)	NC score	0.095731 (rank : 441)
Query Neighborhood Hits	1031	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

SASH1_MOUSE
θ value	0.00134147 (rank : 295)	NC score	0.136758 (rank : 336)
Query Neighborhood Hits	1031	Target Neighborhood Hits	263	Shared Neighborhood Hits	122
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

EPHAA_HUMAN
θ value	0.00175202 (rank : 296)	NC score	0.109085 (rank : 384)
Query Neighborhood Hits	1031	Target Neighborhood Hits	960	Shared Neighborhood Hits	107
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

HRBL_MOUSE
θ value	0.00175202 (rank : 297)	NC score	0.074475 (rank : 543)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	99
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

PRP1_HUMAN
θ value	0.00175202 (rank : 298)	NC score	0.175255 (rank : 300)
Query Neighborhood Hits	1031	Target Neighborhood Hits	385	Shared Neighborhood Hits	178
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SEPT9_HUMAN
θ value	0.00175202 (rank : 299)	NC score	0.067502 (rank : 602)
Query Neighborhood Hits	1031	Target Neighborhood Hits	706	Shared Neighborhood Hits	248
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TRPV1_MOUSE
θ value	0.00175202 (rank : 300)	NC score	0.238516 (rank : 285)
Query Neighborhood Hits	1031	Target Neighborhood Hits	189	Shared Neighborhood Hits	154
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

AHI1_HUMAN
θ value	0.00228821 (rank : 301)	NC score	0.039765 (rank : 986)
Query Neighborhood Hits	1031	Target Neighborhood Hits	537	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AN13C_MOUSE
θ value	0.00228821 (rank : 302)	NC score	0.501637 (rank : 231)
Query Neighborhood Hits	1031	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

DGKZ_MOUSE
θ value	0.00228821 (rank : 303)	NC score	0.349987 (rank : 269)
Query Neighborhood Hits	1031	Target Neighborhood Hits	542	Shared Neighborhood Hits	210
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

EPHA6_MOUSE
θ value	0.00228821 (rank : 304)	NC score	0.109016 (rank : 385)
Query Neighborhood Hits	1031	Target Neighborhood Hits	946	Shared Neighborhood Hits	99
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

FA47A_HUMAN
θ value	0.00228821 (rank : 305)	NC score	0.121022 (rank : 353)
Query Neighborhood Hits	1031	Target Neighborhood Hits	451	Shared Neighborhood Hits	185
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

TEX14_HUMAN
θ value	0.00228821 (rank : 306)	NC score	0.411879 (rank : 258)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1103	Shared Neighborhood Hits	340
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

WASIP_HUMAN
θ value	0.00228821 (rank : 307)	NC score	0.197539 (rank : 295)
Query Neighborhood Hits	1031	Target Neighborhood Hits	458	Shared Neighborhood Hits	222
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ANR43_MOUSE
θ value	0.00298849 (rank : 308)	NC score	0.589835 (rank : 198)
Query Neighborhood Hits	1031	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CDN2B_HUMAN
θ value	0.00298849 (rank : 309)	NC score	0.591216 (rank : 196)
Query Neighborhood Hits	1031	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CENG2_HUMAN
θ value	0.00298849 (rank : 310)	NC score	0.337765 (rank : 271)
Query Neighborhood Hits	1031	Target Neighborhood Hits	471	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CLPB_MOUSE
θ value	0.00298849 (rank : 311)	NC score	0.643567 (rank : 184)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	252
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

AN13C_HUMAN
θ value	0.00390308 (rank : 312)	NC score	0.510507 (rank : 228)
Query Neighborhood Hits	1031	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

CLR59_HUMAN
θ value	0.00390308 (rank : 313)	NC score	0.310161 (rank : 278)
Query Neighborhood Hits	1031	Target Neighborhood Hits	163	Shared Neighborhood Hits	145
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

LIPB2_MOUSE
θ value	0.00390308 (rank : 314)	NC score	0.064755 (rank : 632)
Query Neighborhood Hits	1031	Target Neighborhood Hits	570	Shared Neighborhood Hits	75
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

LRRK1_HUMAN
θ value	0.00390308 (rank : 315)	NC score	0.103013 (rank : 420)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1237	Shared Neighborhood Hits	163
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

NUD12_MOUSE
θ value	0.00390308 (rank : 316)	NC score	0.553589 (rank : 211)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	219
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

TRPV6_HUMAN
θ value	0.00390308 (rank : 317)	NC score	0.447444 (rank : 247)
Query Neighborhood Hits	1031	Target Neighborhood Hits	262	Shared Neighborhood Hits	225
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

WASIP_MOUSE
θ value	0.00390308 (rank : 318)	NC score	0.174503 (rank : 301)
Query Neighborhood Hits	1031	Target Neighborhood Hits	392	Shared Neighborhood Hits	205
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WBP11_HUMAN
θ value	0.00390308 (rank : 319)	NC score	0.138486 (rank : 331)
Query Neighborhood Hits	1031	Target Neighborhood Hits	354	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	0.00390308 (rank : 320)	NC score	0.138760 (rank : 330)
Query Neighborhood Hits	1031	Target Neighborhood Hits	362	Shared Neighborhood Hits	153
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ANR43_HUMAN
θ value	0.00509761 (rank : 321)	NC score	0.590362 (rank : 197)
Query Neighborhood Hits	1031	Target Neighborhood Hits	209	Shared Neighborhood Hits	200
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CENG1_MOUSE
θ value	0.00509761 (rank : 322)	NC score	0.350611 (rank : 266)
Query Neighborhood Hits	1031	Target Neighborhood Hits	531	Shared Neighborhood Hits	300
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CIC_HUMAN
θ value	0.00509761 (rank : 323)	NC score	0.111342 (rank : 374)
Query Neighborhood Hits	1031	Target Neighborhood Hits	992	Shared Neighborhood Hits	365
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

EPHB6_MOUSE
θ value	0.00509761 (rank : 324)	NC score	0.112832 (rank : 370)
Query Neighborhood Hits	1031	Target Neighborhood Hits	906	Shared Neighborhood Hits	109
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FMNL_HUMAN
θ value	0.00509761 (rank : 325)	NC score	0.100736 (rank : 428)
Query Neighborhood Hits	1031	Target Neighborhood Hits	529	Shared Neighborhood Hits	188
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

NFAC1_HUMAN
θ value	0.00509761 (rank : 326)	NC score	0.054409 (rank : 829)
Query Neighborhood Hits	1031	Target Neighborhood Hits	312	Shared Neighborhood Hits	139
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

CENG1_HUMAN
θ value	0.00665767 (rank : 327)	NC score	0.348036 (rank : 270)
Query Neighborhood Hits	1031	Target Neighborhood Hits	544	Shared Neighborhood Hits	303
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG2_MOUSE
θ value	0.00665767 (rank : 328)	NC score	0.335049 (rank : 273)
Query Neighborhood Hits	1031	Target Neighborhood Hits	463	Shared Neighborhood Hits	261
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CNTRB_MOUSE
θ value	0.00665767 (rank : 329)	NC score	0.054862 (rank : 822)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1029	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

HSF1_MOUSE
θ value	0.00665767 (rank : 330)	NC score	0.064699 (rank : 635)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	109
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

IF4G1_MOUSE
θ value	0.00665767 (rank : 331)	NC score	0.072501 (rank : 564)
Query Neighborhood Hits	1031	Target Neighborhood Hits	534	Shared Neighborhood Hits	197
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PRR8_HUMAN
θ value	0.00665767 (rank : 332)	NC score	0.106744 (rank : 407)
Query Neighborhood Hits	1031	Target Neighborhood Hits	217	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

CDN2B_MOUSE
θ value	0.00869519 (rank : 333)	NC score	0.637959 (rank : 185)
Query Neighborhood Hits	1031	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CEL_HUMAN
θ value	0.00869519 (rank : 334)	NC score	0.099172 (rank : 432)
Query Neighborhood Hits	1031	Target Neighborhood Hits	896	Shared Neighborhood Hits	325
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CS007_MOUSE
θ value	0.00869519 (rank : 335)	NC score	0.105415 (rank : 410)
Query Neighborhood Hits	1031	Target Neighborhood Hits	464	Shared Neighborhood Hits	175
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

GGN_MOUSE
θ value	0.00869519 (rank : 336)	NC score	0.123043 (rank : 350)
Query Neighborhood Hits	1031	Target Neighborhood Hits	311	Shared Neighborhood Hits	153
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SEPT9_MOUSE
θ value	0.00869519 (rank : 337)	NC score	0.028415 (rank : 1092)
Query Neighborhood Hits	1031	Target Neighborhood Hits	238	Shared Neighborhood Hits	64
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

TRPV2_HUMAN
θ value	0.00869519 (rank : 338)	NC score	0.213825 (rank : 291)
Query Neighborhood Hits	1031	Target Neighborhood Hits	130	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

WASF3_MOUSE
θ value	0.00869519 (rank : 339)	NC score	0.082842 (rank : 502)
Query Neighborhood Hits	1031	Target Neighborhood Hits	188	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

3BP1_HUMAN
θ value	0.0113563 (rank : 340)	NC score	0.072858 (rank : 561)
Query Neighborhood Hits	1031	Target Neighborhood Hits	376	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ASB6_HUMAN
θ value	0.0113563 (rank : 341)	NC score	0.684766 (rank : 169)
Query Neighborhood Hits	1031	Target Neighborhood Hits	256	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB6_MOUSE
θ value	0.0113563 (rank : 342)	NC score	0.679234 (rank : 174)
Query Neighborhood Hits	1031	Target Neighborhood Hits	264	Shared Neighborhood Hits	244
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

BAT2_HUMAN
θ value	0.0113563 (rank : 343)	NC score	0.151620 (rank : 319)
Query Neighborhood Hits	1031	Target Neighborhood Hits	931	Shared Neighborhood Hits	340
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_HUMAN
θ value	0.0113563 (rank : 344)	NC score	0.140594 (rank : 328)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1537	Shared Neighborhood Hits	414
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	0.0113563 (rank : 345)	NC score	0.159418 (rank : 314)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2057	Shared Neighborhood Hits	512
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DGKZ_HUMAN
θ value	0.0113563 (rank : 346)	NC score	0.367088 (rank : 265)
Query Neighborhood Hits	1031	Target Neighborhood Hits	551	Shared Neighborhood Hits	221
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

EPHB6_HUMAN
θ value	0.0113563 (rank : 347)	NC score	0.114098 (rank : 366)
Query Neighborhood Hits	1031	Target Neighborhood Hits	912	Shared Neighborhood Hits	121
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

MKL1_MOUSE
θ value	0.0113563 (rank : 348)	NC score	0.084893 (rank : 491)
Query Neighborhood Hits	1031	Target Neighborhood Hits	667	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SREC2_HUMAN
θ value	0.0113563 (rank : 349)	NC score	0.071063 (rank : 577)
Query Neighborhood Hits	1031	Target Neighborhood Hits	645	Shared Neighborhood Hits	128
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ALEX_HUMAN
θ value	0.0148317 (rank : 350)	NC score	0.125037 (rank : 346)
Query Neighborhood Hits	1031	Target Neighborhood Hits	361	Shared Neighborhood Hits	163
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BCL9_MOUSE
θ value	0.0148317 (rank : 351)	NC score	0.137432 (rank : 333)
Query Neighborhood Hits	1031	Target Neighborhood Hits	770	Shared Neighborhood Hits	308
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BIN1_HUMAN
θ value	0.0148317 (rank : 352)	NC score	0.064307 (rank : 640)
Query Neighborhood Hits	1031	Target Neighborhood Hits	335	Shared Neighborhood Hits	103
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

F100B_MOUSE
θ value	0.0148317 (rank : 353)	NC score	0.050008 (rank : 915)
Query Neighborhood Hits	1031	Target Neighborhood Hits	91	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

SAMD8_MOUSE
θ value	0.0148317 (rank : 354)	NC score	0.040486 (rank : 975)
Query Neighborhood Hits	1031	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DA37	Gene names	Samd8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

SAPS1_HUMAN
θ value	0.0148317 (rank : 355)	NC score	0.094272 (rank : 446)
Query Neighborhood Hits	1031	Target Neighborhood Hits	704	Shared Neighborhood Hits	275
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ZEP1_MOUSE
θ value	0.0148317 (rank : 356)	NC score	0.011165 (rank : 1229)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1063	Shared Neighborhood Hits	141
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

BCAR1_HUMAN
θ value	0.0193708 (rank : 357)	NC score	0.103717 (rank : 417)
Query Neighborhood Hits	1031	Target Neighborhood Hits	554	Shared Neighborhood Hits	231
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

IASPP_HUMAN
θ value	0.0193708 (rank : 358)	NC score	0.566257 (rank : 206)
Query Neighborhood Hits	1031	Target Neighborhood Hits	688	Shared Neighborhood Hits	420
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NR4A3_MOUSE
θ value	0.0193708 (rank : 359)	NC score	0.012014 (rank : 1223)
Query Neighborhood Hits	1031	Target Neighborhood Hits	127	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

PRB3_HUMAN
θ value	0.0193708 (rank : 360)	NC score	0.149170 (rank : 321)
Query Neighborhood Hits	1031	Target Neighborhood Hits	318	Shared Neighborhood Hits	154
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CD248_HUMAN
θ value	0.0252991 (rank : 361)	NC score	0.081805 (rank : 508)
Query Neighborhood Hits	1031	Target Neighborhood Hits	679	Shared Neighborhood Hits	211
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CENB1_HUMAN
θ value	0.0252991 (rank : 362)	NC score	0.522068 (rank : 223)
Query Neighborhood Hits	1031	Target Neighborhood Hits	383	Shared Neighborhood Hits	272
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CLPB_HUMAN
θ value	0.0252991 (rank : 363)	NC score	0.557609 (rank : 209)
Query Neighborhood Hits	1031	Target Neighborhood Hits	265	Shared Neighborhood Hits	234
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

DGKD_HUMAN
θ value	0.0252991 (rank : 364)	NC score	0.088311 (rank : 467)
Query Neighborhood Hits	1031	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

LRRK1_MOUSE
θ value	0.0252991 (rank : 365)	NC score	0.124891 (rank : 347)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1267	Shared Neighborhood Hits	190
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

ZN516_MOUSE
θ value	0.0252991 (rank : 366)	NC score	0.013802 (rank : 1207)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1197	Shared Neighborhood Hits	212
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CBP_HUMAN
θ value	0.0330416 (rank : 367)	NC score	0.115875 (rank : 359)
Query Neighborhood Hits	1031	Target Neighborhood Hits	941	Shared Neighborhood Hits	333
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CMTA2_HUMAN
θ value	0.0330416 (rank : 368)	NC score	0.190087 (rank : 296)
Query Neighborhood Hits	1031	Target Neighborhood Hits	199	Shared Neighborhood Hits	132
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	0.0330416 (rank : 369)	NC score	0.179021 (rank : 299)
Query Neighborhood Hits	1031	Target Neighborhood Hits	216	Shared Neighborhood Hits	128
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CS007_HUMAN
θ value	0.0330416 (rank : 370)	NC score	0.086007 (rank : 483)
Query Neighborhood Hits	1031	Target Neighborhood Hits	401	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DGKH_HUMAN
θ value	0.0330416 (rank : 371)	NC score	0.072887 (rank : 560)
Query Neighborhood Hits	1031	Target Neighborhood Hits	255	Shared Neighborhood Hits	65
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

EPHA3_HUMAN
θ value	0.0330416 (rank : 372)	NC score	0.095165 (rank : 443)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1005	Shared Neighborhood Hits	99
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

GLSK_HUMAN
θ value	0.0330416 (rank : 373)	NC score	0.464460 (rank : 241)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

HRX_HUMAN
θ value	0.0330416 (rank : 374)	NC score	0.084840 (rank : 492)
Query Neighborhood Hits	1031	Target Neighborhood Hits	825	Shared Neighborhood Hits	199
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IASPP_MOUSE
θ value	0.0330416 (rank : 375)	NC score	0.538728 (rank : 214)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1024	Shared Neighborhood Hits	538
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PHLB1_HUMAN
θ value	0.0330416 (rank : 376)	NC score	0.077007 (rank : 529)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1038	Shared Neighborhood Hits	225
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRB4S_HUMAN
θ value	0.0330416 (rank : 377)	NC score	0.155222 (rank : 315)
Query Neighborhood Hits	1031	Target Neighborhood Hits	330	Shared Neighborhood Hits	146
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SOX13_HUMAN
θ value	0.0330416 (rank : 378)	NC score	0.050461 (rank : 902)
Query Neighborhood Hits	1031	Target Neighborhood Hits	464	Shared Neighborhood Hits	168
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SREC2_MOUSE
θ value	0.0330416 (rank : 379)	NC score	0.063632 (rank : 646)
Query Neighborhood Hits	1031	Target Neighborhood Hits	605	Shared Neighborhood Hits	116
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TULP4_HUMAN
θ value	0.0330416 (rank : 380)	NC score	0.071725 (rank : 570)
Query Neighborhood Hits	1031	Target Neighborhood Hits	426	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

CBP_MOUSE
θ value	0.0431538 (rank : 381)	NC score	0.119411 (rank : 355)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1051	Shared Neighborhood Hits	347
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CECR2_HUMAN
θ value	0.0431538 (rank : 382)	NC score	0.085989 (rank : 484)
Query Neighborhood Hits	1031	Target Neighborhood Hits	543	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CEND3_MOUSE
θ value	0.0431538 (rank : 383)	NC score	0.095244 (rank : 442)
Query Neighborhood Hits	1031	Target Neighborhood Hits	228	Shared Neighborhood Hits	96
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CPSF6_HUMAN
θ value	0.0431538 (rank : 384)	NC score	0.108745 (rank : 389)
Query Neighborhood Hits	1031	Target Neighborhood Hits	359	Shared Neighborhood Hits	137
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	0.0431538 (rank : 385)	NC score	0.109856 (rank : 379)
Query Neighborhood Hits	1031	Target Neighborhood Hits	356	Shared Neighborhood Hits	139
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

LCP2_HUMAN
θ value	0.0431538 (rank : 386)	NC score	0.117879 (rank : 356)
Query Neighborhood Hits	1031	Target Neighborhood Hits	531	Shared Neighborhood Hits	219
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MEGF9_MOUSE
θ value	0.0431538 (rank : 387)	NC score	0.082662 (rank : 504)
Query Neighborhood Hits	1031	Target Neighborhood Hits	896	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MTR1L_HUMAN
θ value	0.0431538 (rank : 388)	NC score	-0.005285 (rank : 1309)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1180	Shared Neighborhood Hits	106
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NUD12_HUMAN
θ value	0.0431538 (rank : 389)	NC score	0.516383 (rank : 226)
Query Neighborhood Hits	1031	Target Neighborhood Hits	222	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

TRPV2_MOUSE
θ value	0.0431538 (rank : 390)	NC score	0.169662 (rank : 306)
Query Neighborhood Hits	1031	Target Neighborhood Hits	111	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

ZDHC5_MOUSE
θ value	0.0431538 (rank : 391)	NC score	0.050842 (rank : 893)
Query Neighborhood Hits	1031	Target Neighborhood Hits	113	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

APXL_HUMAN
θ value	0.0563607 (rank : 392)	NC score	0.058270 (rank : 747)
Query Neighborhood Hits	1031	Target Neighborhood Hits	553	Shared Neighborhood Hits	129
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

FMN2_HUMAN
θ value	0.0563607 (rank : 393)	NC score	0.096850 (rank : 437)
Query Neighborhood Hits	1031	Target Neighborhood Hits	484	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FYB_HUMAN
θ value	0.0563607 (rank : 394)	NC score	0.096355 (rank : 438)
Query Neighborhood Hits	1031	Target Neighborhood Hits	379	Shared Neighborhood Hits	146
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

K1683_HUMAN
θ value	0.0563607 (rank : 395)	NC score	0.080448 (rank : 511)
Query Neighborhood Hits	1031	Target Neighborhood Hits	240	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

PCOC1_HUMAN
θ value	0.0563607 (rank : 396)	NC score	0.012730 (rank : 1217)
Query Neighborhood Hits	1031	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

SASH1_HUMAN
θ value	0.0563607 (rank : 397)	NC score	0.131243 (rank : 341)
Query Neighborhood Hits	1031	Target Neighborhood Hits	292	Shared Neighborhood Hits	161
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SFPQ_MOUSE
θ value	0.0563607 (rank : 398)	NC score	0.100702 (rank : 429)
Query Neighborhood Hits	1031	Target Neighborhood Hits	958	Shared Neighborhood Hits	247
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SLY_HUMAN
θ value	0.0563607 (rank : 399)	NC score	0.085503 (rank : 487)
Query Neighborhood Hits	1031	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SLY_MOUSE
θ value	0.0563607 (rank : 400)	NC score	0.088769 (rank : 463)
Query Neighborhood Hits	1031	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SYNJ1_HUMAN
θ value	0.0563607 (rank : 401)	NC score	0.086970 (rank : 476)
Query Neighborhood Hits	1031	Target Neighborhood Hits	498	Shared Neighborhood Hits	219
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TARSH_HUMAN
θ value	0.0563607 (rank : 402)	NC score	0.162576 (rank : 309)
Query Neighborhood Hits	1031	Target Neighborhood Hits	768	Shared Neighborhood Hits	314
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TLE1_HUMAN
θ value	0.0563607 (rank : 403)	NC score	0.023792 (rank : 1125)
Query Neighborhood Hits	1031	Target Neighborhood Hits	485	Shared Neighborhood Hits	113
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

ENAM_MOUSE
θ value	0.0736092 (rank : 404)	NC score	0.067150 (rank : 606)
Query Neighborhood Hits	1031	Target Neighborhood Hits	229	Shared Neighborhood Hits	95
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

EPHA3_MOUSE
θ value	0.0736092 (rank : 405)	NC score	0.095046 (rank : 444)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	97
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

GA2L2_MOUSE
θ value	0.0736092 (rank : 406)	NC score	0.073706 (rank : 551)
Query Neighborhood Hits	1031	Target Neighborhood Hits	395	Shared Neighborhood Hits	168
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

PTN23_HUMAN
θ value	0.0736092 (rank : 407)	NC score	0.060297 (rank : 702)
Query Neighborhood Hits	1031	Target Neighborhood Hits	646	Shared Neighborhood Hits	195
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SHAN2_HUMAN
θ value	0.0736092 (rank : 408)	NC score	0.108452 (rank : 390)
Query Neighborhood Hits	1031	Target Neighborhood Hits	346	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	0.0736092 (rank : 409)	NC score	0.112205 (rank : 373)
Query Neighborhood Hits	1031	Target Neighborhood Hits	446	Shared Neighborhood Hits	146
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SNIP_HUMAN
θ value	0.0736092 (rank : 410)	NC score	0.052360 (rank : 860)
Query Neighborhood Hits	1031	Target Neighborhood Hits	313	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SRRM1_MOUSE
θ value	0.0736092 (rank : 411)	NC score	0.168197 (rank : 307)
Query Neighborhood Hits	1031	Target Neighborhood Hits	966	Shared Neighborhood Hits	330
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ULK1_MOUSE
θ value	0.0736092 (rank : 412)	NC score	0.055175 (rank : 817)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1214	Shared Neighborhood Hits	256
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

WIRE_MOUSE
θ value	0.0736092 (rank : 413)	NC score	0.154101 (rank : 316)
Query Neighborhood Hits	1031	Target Neighborhood Hits	310	Shared Neighborhood Hits	167
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	0.0736092 (rank : 414)	NC score	0.124470 (rank : 348)
Query Neighborhood Hits	1031	Target Neighborhood Hits	670	Shared Neighborhood Hits	234
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZN341_HUMAN
θ value	0.0736092 (rank : 415)	NC score	-0.009012 (rank : 1314)
Query Neighborhood Hits	1031	Target Neighborhood Hits	803	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ZN385_HUMAN
θ value	0.0736092 (rank : 416)	NC score	0.087202 (rank : 474)
Query Neighborhood Hits	1031	Target Neighborhood Hits	614	Shared Neighborhood Hits	205
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

BCAR1_MOUSE
θ value	0.0961366 (rank : 417)	NC score	0.090501 (rank : 459)
Query Neighborhood Hits	1031	Target Neighborhood Hits	438	Shared Neighborhood Hits	193
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

DYN2_MOUSE
θ value	0.0961366 (rank : 418)	NC score	0.019554 (rank : 1162)
Query Neighborhood Hits	1031	Target Neighborhood Hits	104	Shared Neighborhood Hits	29
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

HAIR_HUMAN
θ value	0.0961366 (rank : 419)	NC score	0.039442 (rank : 989)
Query Neighborhood Hits	1031	Target Neighborhood Hits	172	Shared Neighborhood Hits	63
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

PRR12_HUMAN
θ value	0.0961366 (rank : 420)	NC score	0.159692 (rank : 313)
Query Neighborhood Hits	1031	Target Neighborhood Hits	460	Shared Neighborhood Hits	215
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RTN4_HUMAN
θ value	0.0961366 (rank : 421)	NC score	0.063294 (rank : 647)
Query Neighborhood Hits	1031	Target Neighborhood Hits	357	Shared Neighborhood Hits	126
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SAMN1_MOUSE
θ value	0.0961366 (rank : 422)	NC score	0.088144 (rank : 470)
Query Neighborhood Hits	1031	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

SPR1B_MOUSE
θ value	0.0961366 (rank : 423)	NC score	0.091326 (rank : 456)
Query Neighborhood Hits	1031	Target Neighborhood Hits	395	Shared Neighborhood Hits	180
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SPTA3_MOUSE
θ value	0.0961366 (rank : 424)	NC score	0.075075 (rank : 539)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

SRRM2_MOUSE
θ value	0.0961366 (rank : 425)	NC score	0.133840 (rank : 338)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1470	Shared Neighborhood Hits	358
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TRPC5_HUMAN
θ value	0.0961366 (rank : 426)	NC score	0.069647 (rank : 585)
Query Neighborhood Hits	1031	Target Neighborhood Hits	122	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	0.0961366 (rank : 427)	NC score	0.071119 (rank : 576)
Query Neighborhood Hits	1031	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPV5_HUMAN
θ value	0.0961366 (rank : 428)	NC score	0.443686 (rank : 248)
Query Neighborhood Hits	1031	Target Neighborhood Hits	261	Shared Neighborhood Hits	224
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

WDR46_MOUSE
θ value	0.0961366 (rank : 429)	NC score	0.050367 (rank : 904)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

ZN687_HUMAN
θ value	0.0961366 (rank : 430)	NC score	0.026677 (rank : 1106)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1244	Shared Neighborhood Hits	264
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AFAD_HUMAN
θ value	0.125558 (rank : 431)	NC score	0.026069 (rank : 1111)
Query Neighborhood Hits	1031	Target Neighborhood Hits	689	Shared Neighborhood Hits	89
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ARI1A_HUMAN
θ value	0.125558 (rank : 432)	NC score	0.104907 (rank : 412)
Query Neighborhood Hits	1031	Target Neighborhood Hits	787	Shared Neighborhood Hits	271
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CASL_MOUSE
θ value	0.125558 (rank : 433)	NC score	0.055724 (rank : 805)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CBL_HUMAN
θ value	0.125558 (rank : 434)	NC score	0.032881 (rank : 1060)
Query Neighborhood Hits	1031	Target Neighborhood Hits	353	Shared Neighborhood Hits	88
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CEND3_HUMAN
θ value	0.125558 (rank : 435)	NC score	0.099085 (rank : 433)
Query Neighborhood Hits	1031	Target Neighborhood Hits	275	Shared Neighborhood Hits	117
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CMTA1_HUMAN
θ value	0.125558 (rank : 436)	NC score	0.211509 (rank : 293)
Query Neighborhood Hits	1031	Target Neighborhood Hits	217	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

GNAS1_MOUSE
θ value	0.125558 (rank : 437)	NC score	0.054902 (rank : 820)
Query Neighborhood Hits	1031	Target Neighborhood Hits	651	Shared Neighborhood Hits	235
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GSCR1_HUMAN
θ value	0.125558 (rank : 438)	NC score	0.160171 (rank : 310)
Query Neighborhood Hits	1031	Target Neighborhood Hits	674	Shared Neighborhood Hits	290
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HXA3_MOUSE
θ value	0.125558 (rank : 439)	NC score	0.021649 (rank : 1143)
Query Neighborhood Hits	1031	Target Neighborhood Hits	558	Shared Neighborhood Hits	134
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

JADE2_MOUSE
θ value	0.125558 (rank : 440)	NC score	0.054901 (rank : 821)
Query Neighborhood Hits	1031	Target Neighborhood Hits	560	Shared Neighborhood Hits	194
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

K1802_HUMAN
θ value	0.125558 (rank : 441)	NC score	0.091311 (rank : 457)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1378	Shared Neighborhood Hits	337
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MYO15_HUMAN
θ value	0.125558 (rank : 442)	NC score	0.040356 (rank : 978)
Query Neighborhood Hits	1031	Target Neighborhood Hits	671	Shared Neighborhood Hits	270
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PCD15_MOUSE
θ value	0.125558 (rank : 443)	NC score	0.005354 (rank : 1278)
Query Neighborhood Hits	1031	Target Neighborhood Hits	262	Shared Neighborhood Hits	65
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

S23IP_MOUSE
θ value	0.125558 (rank : 444)	NC score	0.098346 (rank : 434)
Query Neighborhood Hits	1031	Target Neighborhood Hits	363	Shared Neighborhood Hits	165
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SAMN1_HUMAN
θ value	0.125558 (rank : 445)	NC score	0.088368 (rank : 466)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

WASL_MOUSE
θ value	0.125558 (rank : 446)	NC score	0.115451 (rank : 360)
Query Neighborhood Hits	1031	Target Neighborhood Hits	339	Shared Neighborhood Hits	184
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ANKY1_HUMAN
θ value	0.163984 (rank : 447)	NC score	0.517091 (rank : 225)
Query Neighborhood Hits	1031	Target Neighborhood Hits	248	Shared Neighborhood Hits	208
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

C2TA_HUMAN
θ value	0.163984 (rank : 448)	NC score	0.040483 (rank : 976)
Query Neighborhood Hits	1031	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CAC1G_HUMAN
θ value	0.163984 (rank : 449)	NC score	0.036967 (rank : 1012)
Query Neighborhood Hits	1031	Target Neighborhood Hits	587	Shared Neighborhood Hits	203
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

DCC_MOUSE
θ value	0.163984 (rank : 450)	NC score	0.038644 (rank : 1000)
Query Neighborhood Hits	1031	Target Neighborhood Hits	896	Shared Neighborhood Hits	230
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

F100B_HUMAN
θ value	0.163984 (rank : 451)	NC score	0.033600 (rank : 1051)
Query Neighborhood Hits	1031	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IYN6	Gene names	FAM100B
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

GBF1_HUMAN
θ value	0.163984 (rank : 452)	NC score	0.022954 (rank : 1130)
Query Neighborhood Hits	1031	Target Neighborhood Hits	142	Shared Neighborhood Hits	46
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

IKBL_HUMAN
θ value	0.163984 (rank : 453)	NC score	0.323059 (rank : 275)
Query Neighborhood Hits	1031	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	0.163984 (rank : 454)	NC score	0.315465 (rank : 277)
Query Neighborhood Hits	1031	Target Neighborhood Hits	196	Shared Neighborhood Hits	140
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

LTB1L_HUMAN
θ value	0.163984 (rank : 455)	NC score	0.052294 (rank : 863)
Query Neighborhood Hits	1031	Target Neighborhood Hits	553	Shared Neighborhood Hits	88
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.163984 (rank : 456)	NC score	0.050697 (rank : 897)
Query Neighborhood Hits	1031	Target Neighborhood Hits	502	Shared Neighborhood Hits	70
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NCOR2_MOUSE
θ value	0.163984 (rank : 457)	NC score	0.069023 (rank : 588)
Query Neighborhood Hits	1031	Target Neighborhood Hits	790	Shared Neighborhood Hits	178
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NR4A3_HUMAN
θ value	0.163984 (rank : 458)	NC score	0.009006 (rank : 1248)
Query Neighborhood Hits	1031	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

SMAD5_HUMAN
θ value	0.163984 (rank : 459)	NC score	0.020113 (rank : 1159)
Query Neighborhood Hits	1031	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

SMAD5_MOUSE
θ value	0.163984 (rank : 460)	NC score	0.023015 (rank : 1128)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	24
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

SMCA4_HUMAN
θ value	0.163984 (rank : 461)	NC score	0.038195 (rank : 1003)
Query Neighborhood Hits	1031	Target Neighborhood Hits	597	Shared Neighborhood Hits	178
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

STAC_HUMAN
θ value	0.163984 (rank : 462)	NC score	0.058880 (rank : 729)
Query Neighborhood Hits	1031	Target Neighborhood Hits	276	Shared Neighborhood Hits	65
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

WASP_MOUSE
θ value	0.163984 (rank : 463)	NC score	0.102684 (rank : 422)
Query Neighborhood Hits	1031	Target Neighborhood Hits	223	Shared Neighborhood Hits	113
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WNK2_HUMAN
θ value	0.163984 (rank : 464)	NC score	0.075402 (rank : 536)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1407	Shared Neighborhood Hits	325
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZEP2_MOUSE
θ value	0.163984 (rank : 465)	NC score	0.004699 (rank : 1281)
Query Neighborhood Hits	1031	Target Neighborhood Hits	964	Shared Neighborhood Hits	121
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

AMOL1_MOUSE
θ value	0.21417 (rank : 466)	NC score	0.039379 (rank : 990)
Query Neighborhood Hits	1031	Target Neighborhood Hits	445	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

ANKZ1_HUMAN
θ value	0.21417 (rank : 467)	NC score	0.318357 (rank : 276)
Query Neighborhood Hits	1031	Target Neighborhood Hits	236	Shared Neighborhood Hits	164
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

MAGD4_HUMAN
θ value	0.21417 (rank : 468)	NC score	0.037333 (rank : 1007)
Query Neighborhood Hits	1031	Target Neighborhood Hits	338	Shared Neighborhood Hits	128
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MILK1_MOUSE
θ value	0.21417 (rank : 469)	NC score	0.091029 (rank : 458)
Query Neighborhood Hits	1031	Target Neighborhood Hits	788	Shared Neighborhood Hits	292
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PRG4_HUMAN
θ value	0.21417 (rank : 470)	NC score	0.140448 (rank : 329)
Query Neighborhood Hits	1031	Target Neighborhood Hits	764	Shared Neighborhood Hits	257
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP2_MOUSE
θ value	0.21417 (rank : 471)	NC score	0.173804 (rank : 303)
Query Neighborhood Hits	1031	Target Neighborhood Hits	347	Shared Neighborhood Hits	174
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR13_MOUSE
θ value	0.21417 (rank : 472)	NC score	0.093187 (rank : 451)
Query Neighborhood Hits	1031	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PTN14_MOUSE
θ value	0.21417 (rank : 473)	NC score	0.007015 (rank : 1266)
Query Neighborhood Hits	1031	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

RTN1_HUMAN
θ value	0.21417 (rank : 474)	NC score	0.044572 (rank : 947)
Query Neighborhood Hits	1031	Target Neighborhood Hits	173	Shared Neighborhood Hits	61
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SMAD1_HUMAN
θ value	0.21417 (rank : 475)	NC score	0.024898 (rank : 1120)
Query Neighborhood Hits	1031	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SSBP4_HUMAN
θ value	0.21417 (rank : 476)	NC score	0.091350 (rank : 455)
Query Neighborhood Hits	1031	Target Neighborhood Hits	753	Shared Neighborhood Hits	288
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

STAC_MOUSE
θ value	0.21417 (rank : 477)	NC score	0.058779 (rank : 734)
Query Neighborhood Hits	1031	Target Neighborhood Hits	268	Shared Neighborhood Hits	64
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TITIN_HUMAN
θ value	0.21417 (rank : 478)	NC score	0.043274 (rank : 954)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2923	Shared Neighborhood Hits	364
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TLE1_MOUSE
θ value	0.21417 (rank : 479)	NC score	0.022793 (rank : 1132)
Query Neighborhood Hits	1031	Target Neighborhood Hits	491	Shared Neighborhood Hits	112
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

WASP_HUMAN
θ value	0.21417 (rank : 480)	NC score	0.087101 (rank : 475)
Query Neighborhood Hits	1031	Target Neighborhood Hits	195	Shared Neighborhood Hits	115
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

YLPM1_MOUSE
θ value	0.21417 (rank : 481)	NC score	0.126801 (rank : 344)
Query Neighborhood Hits	1031	Target Neighborhood Hits	505	Shared Neighborhood Hits	200
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ADA12_MOUSE
θ value	0.279714 (rank : 482)	NC score	0.027479 (rank : 1102)
Query Neighborhood Hits	1031	Target Neighborhood Hits	474	Shared Neighborhood Hits	156
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ANKZ1_MOUSE
θ value	0.279714 (rank : 483)	NC score	0.336938 (rank : 272)
Query Neighborhood Hits	1031	Target Neighborhood Hits	208	Shared Neighborhood Hits	157
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ASB14_HUMAN
θ value	0.279714 (rank : 484)	NC score	0.511046 (rank : 227)
Query Neighborhood Hits	1031	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CT032_HUMAN
θ value	0.279714 (rank : 485)	NC score	0.063041 (rank : 650)
Query Neighborhood Hits	1031	Target Neighborhood Hits	235	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

HDAC9_HUMAN
θ value	0.279714 (rank : 486)	NC score	0.014798 (rank : 1196)
Query Neighborhood Hits	1031	Target Neighborhood Hits	201	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

HXA3_HUMAN
θ value	0.279714 (rank : 487)	NC score	0.015859 (rank : 1186)
Query Neighborhood Hits	1031	Target Neighborhood Hits	535	Shared Neighborhood Hits	118
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

K1543_MOUSE
θ value	0.279714 (rank : 488)	NC score	0.103568 (rank : 419)
Query Neighborhood Hits	1031	Target Neighborhood Hits	497	Shared Neighborhood Hits	196
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LTBP4_MOUSE
θ value	0.279714 (rank : 489)	NC score	0.058418 (rank : 745)
Query Neighborhood Hits	1031	Target Neighborhood Hits	607	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

PER1_MOUSE
θ value	0.279714 (rank : 490)	NC score	0.040069 (rank : 982)
Query Neighborhood Hits	1031	Target Neighborhood Hits	235	Shared Neighborhood Hits	103
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

SIN3A_MOUSE
θ value	0.279714 (rank : 491)	NC score	0.034323 (rank : 1043)
Query Neighborhood Hits	1031	Target Neighborhood Hits	169	Shared Neighborhood Hits	72
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SMAD1_MOUSE
θ value	0.279714 (rank : 492)	NC score	0.023448 (rank : 1127)
Query Neighborhood Hits	1031	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SNRPA_MOUSE
θ value	0.279714 (rank : 493)	NC score	0.027735 (rank : 1098)
Query Neighborhood Hits	1031	Target Neighborhood Hits	129	Shared Neighborhood Hits	25
SwissProt Accessions	Q62189, Q52LA2	Gene names	Snrpa, Rnu1a-1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein A (U1 snRNP protein A) (U1A protein) (U1-A).

SYN1_MOUSE
θ value	0.279714 (rank : 494)	NC score	0.096201 (rank : 439)
Query Neighborhood Hits	1031	Target Neighborhood Hits	363	Shared Neighborhood Hits	175
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

WASF1_HUMAN
θ value	0.279714 (rank : 495)	NC score	0.097308 (rank : 436)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	148
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	0.279714 (rank : 496)	NC score	0.099914 (rank : 431)
Query Neighborhood Hits	1031	Target Neighborhood Hits	261	Shared Neighborhood Hits	150
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

ARRD1_MOUSE
θ value	0.365318 (rank : 497)	NC score	0.032291 (rank : 1064)
Query Neighborhood Hits	1031	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

BAT2_MOUSE
θ value	0.365318 (rank : 498)	NC score	0.137061 (rank : 335)
Query Neighborhood Hits	1031	Target Neighborhood Hits	947	Shared Neighborhood Hits	352
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CITE4_HUMAN
θ value	0.365318 (rank : 499)	NC score	0.064818 (rank : 631)
Query Neighborhood Hits	1031	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

CO039_MOUSE
θ value	0.365318 (rank : 500)	NC score	0.088972 (rank : 462)
Query Neighborhood Hits	1031	Target Neighborhood Hits	445	Shared Neighborhood Hits	210
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CUTL1_HUMAN
θ value	0.365318 (rank : 501)	NC score	0.038831 (rank : 997)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1574	Shared Neighborhood Hits	198
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GGA3_MOUSE
θ value	0.365318 (rank : 502)	NC score	0.034961 (rank : 1035)
Query Neighborhood Hits	1031	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

LIPA3_HUMAN
θ value	0.365318 (rank : 503)	NC score	0.033417 (rank : 1053)
Query Neighborhood Hits	1031	Target Neighborhood Hits	828	Shared Neighborhood Hits	99
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MYLK_MOUSE
θ value	0.365318 (rank : 504)	NC score	0.042303 (rank : 963)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1489	Shared Neighborhood Hits	200
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PGCB_MOUSE
θ value	0.365318 (rank : 505)	NC score	0.024342 (rank : 1122)
Query Neighborhood Hits	1031	Target Neighborhood Hits	459	Shared Neighborhood Hits	54
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PSL1_HUMAN
θ value	0.365318 (rank : 506)	NC score	0.084943 (rank : 490)
Query Neighborhood Hits	1031	Target Neighborhood Hits	650	Shared Neighborhood Hits	265
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PTN14_HUMAN
θ value	0.365318 (rank : 507)	NC score	0.006935 (rank : 1267)
Query Neighborhood Hits	1031	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

RFX1_HUMAN
θ value	0.365318 (rank : 508)	NC score	0.052992 (rank : 853)
Query Neighborhood Hits	1031	Target Neighborhood Hits	256	Shared Neighborhood Hits	119
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SF3B4_HUMAN
θ value	0.365318 (rank : 509)	NC score	0.040472 (rank : 977)
Query Neighborhood Hits	1031	Target Neighborhood Hits	445	Shared Neighborhood Hits	115
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

STAM1_MOUSE
θ value	0.365318 (rank : 510)	NC score	0.054564 (rank : 827)
Query Neighborhood Hits	1031	Target Neighborhood Hits	273	Shared Neighborhood Hits	75
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TIP60_MOUSE
θ value	0.365318 (rank : 511)	NC score	0.022303 (rank : 1134)
Query Neighborhood Hits	1031	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TRPV1_HUMAN
θ value	0.365318 (rank : 512)	NC score	0.216399 (rank : 290)
Query Neighborhood Hits	1031	Target Neighborhood Hits	184	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

VASP_MOUSE
θ value	0.365318 (rank : 513)	NC score	0.067763 (rank : 598)
Query Neighborhood Hits	1031	Target Neighborhood Hits	195	Shared Neighborhood Hits	93
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

WASF3_HUMAN
θ value	0.365318 (rank : 514)	NC score	0.079613 (rank : 513)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

ZN575_HUMAN
θ value	0.365318 (rank : 515)	NC score	-0.013083 (rank : 1316)
Query Neighborhood Hits	1031	Target Neighborhood Hits	739	Shared Neighborhood Hits	43
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

AAK1_HUMAN
θ value	0.47712 (rank : 516)	NC score	0.044932 (rank : 944)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1077	Shared Neighborhood Hits	211
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ARHG6_MOUSE
θ value	0.47712 (rank : 517)	NC score	0.038842 (rank : 996)
Query Neighborhood Hits	1031	Target Neighborhood Hits	394	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG7_HUMAN
θ value	0.47712 (rank : 518)	NC score	0.035972 (rank : 1022)
Query Neighborhood Hits	1031	Target Neighborhood Hits	347	Shared Neighborhood Hits	74
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

BAG3_MOUSE
θ value	0.47712 (rank : 519)	NC score	0.102027 (rank : 424)
Query Neighborhood Hits	1031	Target Neighborhood Hits	513	Shared Neighborhood Hits	232
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CO3A1_HUMAN
θ value	0.47712 (rank : 520)	NC score	0.046610 (rank : 929)
Query Neighborhood Hits	1031	Target Neighborhood Hits	452	Shared Neighborhood Hits	134
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	0.47712 (rank : 521)	NC score	0.046459 (rank : 930)
Query Neighborhood Hits	1031	Target Neighborhood Hits	466	Shared Neighborhood Hits	137
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CT174_HUMAN
θ value	0.47712 (rank : 522)	NC score	0.059104 (rank : 725)
Query Neighborhood Hits	1031	Target Neighborhood Hits	181	Shared Neighborhood Hits	73
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

FOXO1_MOUSE
θ value	0.47712 (rank : 523)	NC score	0.007844 (rank : 1256)
Query Neighborhood Hits	1031	Target Neighborhood Hits	118	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

LRSM1_MOUSE
θ value	0.47712 (rank : 524)	NC score	0.040879 (rank : 972)
Query Neighborhood Hits	1031	Target Neighborhood Hits	874	Shared Neighborhood Hits	74
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MAST3_HUMAN
θ value	0.47712 (rank : 525)	NC score	0.036371 (rank : 1018)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1128	Shared Neighborhood Hits	178
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MEFV_HUMAN
θ value	0.47712 (rank : 526)	NC score	0.005925 (rank : 1273)
Query Neighborhood Hits	1031	Target Neighborhood Hits	431	Shared Neighborhood Hits	62
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PDXL2_HUMAN
θ value	0.47712 (rank : 527)	NC score	0.032376 (rank : 1063)
Query Neighborhood Hits	1031	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

POGZ_MOUSE
θ value	0.47712 (rank : 528)	NC score	-0.006029 (rank : 1311)
Query Neighborhood Hits	1031	Target Neighborhood Hits	765	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

RT23_MOUSE
θ value	0.47712 (rank : 529)	NC score	0.020766 (rank : 1155)
Query Neighborhood Hits	1031	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VE22, Q9CXH1	Gene names	Mrps23
Domain Architecture	No domain graphic available
Description	Mitochondrial ribosomal protein S23 (S23mt) (MRP-S23).

SEM6C_MOUSE
θ value	0.47712 (rank : 530)	NC score	0.025318 (rank : 1116)
Query Neighborhood Hits	1031	Target Neighborhood Hits	352	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEN2_MOUSE
θ value	0.47712 (rank : 531)	NC score	0.017056 (rank : 1177)
Query Neighborhood Hits	1031	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

SFPQ_HUMAN
θ value	0.47712 (rank : 532)	NC score	0.094088 (rank : 447)
Query Neighborhood Hits	1031	Target Neighborhood Hits	986	Shared Neighborhood Hits	256
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SNRPA_HUMAN
θ value	0.47712 (rank : 533)	NC score	0.027557 (rank : 1101)
Query Neighborhood Hits	1031	Target Neighborhood Hits	128	Shared Neighborhood Hits	24
SwissProt Accessions	P09012	Gene names	SNRPA
Domain Architecture
Description	U1 small nuclear ribonucleoprotein A (U1 snRNP protein A) (U1A protein) (U1-A).

SPHK2_HUMAN
θ value	0.47712 (rank : 534)	NC score	0.025609 (rank : 1113)
Query Neighborhood Hits	1031	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

TCRG1_HUMAN
θ value	0.47712 (rank : 535)	NC score	0.064144 (rank : 641)
Query Neighborhood Hits	1031	Target Neighborhood Hits	929	Shared Neighborhood Hits	157
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TIP60_HUMAN
θ value	0.47712 (rank : 536)	NC score	0.022171 (rank : 1137)
Query Neighborhood Hits	1031	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

ATX2_MOUSE
θ value	0.62314 (rank : 537)	NC score	0.075808 (rank : 535)
Query Neighborhood Hits	1031	Target Neighborhood Hits	445	Shared Neighborhood Hits	173
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CABL2_MOUSE
θ value	0.62314 (rank : 538)	NC score	0.029234 (rank : 1086)
Query Neighborhood Hits	1031	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

CBX2_HUMAN
θ value	0.62314 (rank : 539)	NC score	0.046142 (rank : 932)
Query Neighborhood Hits	1031	Target Neighborhood Hits	264	Shared Neighborhood Hits	87
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CJ078_MOUSE
θ value	0.62314 (rank : 540)	NC score	0.114634 (rank : 364)
Query Neighborhood Hits	1031	Target Neighborhood Hits	559	Shared Neighborhood Hits	165
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	0.62314 (rank : 541)	NC score	0.119565 (rank : 354)
Query Neighborhood Hits	1031	Target Neighborhood Hits	408	Shared Neighborhood Hits	184
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CK024_MOUSE
θ value	0.62314 (rank : 542)	NC score	0.065900 (rank : 619)
Query Neighborhood Hits	1031	Target Neighborhood Hits	307	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CO4A4_HUMAN
θ value	0.62314 (rank : 543)	NC score	0.041074 (rank : 970)
Query Neighborhood Hits	1031	Target Neighborhood Hits	440	Shared Neighborhood Hits	134
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

COAA1_HUMAN
θ value	0.62314 (rank : 544)	NC score	0.034233 (rank : 1044)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	101
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COBA2_HUMAN
θ value	0.62314 (rank : 545)	NC score	0.031929 (rank : 1067)
Query Neighborhood Hits	1031	Target Neighborhood Hits	408	Shared Neighborhood Hits	108
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

ESX1L_HUMAN
θ value	0.62314 (rank : 546)	NC score	0.017495 (rank : 1176)
Query Neighborhood Hits	1031	Target Neighborhood Hits	498	Shared Neighborhood Hits	95
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

GGA3_HUMAN
θ value	0.62314 (rank : 547)	NC score	0.028929 (rank : 1089)
Query Neighborhood Hits	1031	Target Neighborhood Hits	127	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GP152_MOUSE
θ value	0.62314 (rank : 548)	NC score	0.017724 (rank : 1173)
Query Neighborhood Hits	1031	Target Neighborhood Hits	607	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

HCN4_MOUSE
θ value	0.62314 (rank : 549)	NC score	0.034206 (rank : 1045)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	119
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MAST1_HUMAN
θ value	0.62314 (rank : 550)	NC score	0.035765 (rank : 1024)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1146	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MBB1A_HUMAN
θ value	0.62314 (rank : 551)	NC score	0.076960 (rank : 530)
Query Neighborhood Hits	1031	Target Neighborhood Hits	665	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MICA2_HUMAN
θ value	0.62314 (rank : 552)	NC score	0.005393 (rank : 1277)
Query Neighborhood Hits	1031	Target Neighborhood Hits	174	Shared Neighborhood Hits	19
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

OTU7A_HUMAN
θ value	0.62314 (rank : 553)	NC score	0.014191 (rank : 1204)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

PAK4_MOUSE
θ value	0.62314 (rank : 554)	NC score	0.043585 (rank : 951)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1098	Shared Neighborhood Hits	184
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PKHG4_HUMAN
θ value	0.62314 (rank : 555)	NC score	0.026069 (rank : 1112)
Query Neighborhood Hits	1031	Target Neighborhood Hits	200	Shared Neighborhood Hits	53
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PKN3_MOUSE
θ value	0.62314 (rank : 556)	NC score	0.035544 (rank : 1027)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	136
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PO6F2_HUMAN
θ value	0.62314 (rank : 557)	NC score	0.036802 (rank : 1013)
Query Neighborhood Hits	1031	Target Neighborhood Hits	618	Shared Neighborhood Hits	138
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PRGR_MOUSE
θ value	0.62314 (rank : 558)	NC score	0.013313 (rank : 1210)
Query Neighborhood Hits	1031	Target Neighborhood Hits	286	Shared Neighborhood Hits	81
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

RIMB1_HUMAN
θ value	0.62314 (rank : 559)	NC score	0.060748 (rank : 687)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1479	Shared Neighborhood Hits	262
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ROBO3_HUMAN
θ value	0.62314 (rank : 560)	NC score	0.016584 (rank : 1181)
Query Neighborhood Hits	1031	Target Neighborhood Hits	570	Shared Neighborhood Hits	87
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

SAMD8_HUMAN
θ value	0.62314 (rank : 561)	NC score	0.030805 (rank : 1074)
Query Neighborhood Hits	1031	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q96LT4	Gene names	SAMD8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

STAM1_HUMAN
θ value	0.62314 (rank : 562)	NC score	0.052911 (rank : 854)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	70
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TCRG1_MOUSE
θ value	0.62314 (rank : 563)	NC score	0.065745 (rank : 621)
Query Neighborhood Hits	1031	Target Neighborhood Hits	947	Shared Neighborhood Hits	175
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TP53B_MOUSE
θ value	0.62314 (rank : 564)	NC score	0.067590 (rank : 601)
Query Neighborhood Hits	1031	Target Neighborhood Hits	644	Shared Neighborhood Hits	166
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRPC4_HUMAN
θ value	0.62314 (rank : 565)	NC score	0.065062 (rank : 626)
Query Neighborhood Hits	1031	Target Neighborhood Hits	140	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	0.62314 (rank : 566)	NC score	0.065210 (rank : 625)
Query Neighborhood Hits	1031	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TTP_HUMAN
θ value	0.62314 (rank : 567)	NC score	0.021490 (rank : 1146)
Query Neighborhood Hits	1031	Target Neighborhood Hits	86	Shared Neighborhood Hits	28
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

WASL_HUMAN
θ value	0.62314 (rank : 568)	NC score	0.112420 (rank : 371)
Query Neighborhood Hits	1031	Target Neighborhood Hits	312	Shared Neighborhood Hits	168
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZIMP7_MOUSE
θ value	0.62314 (rank : 569)	NC score	0.076102 (rank : 531)
Query Neighborhood Hits	1031	Target Neighborhood Hits	566	Shared Neighborhood Hits	232
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN438_HUMAN
θ value	0.62314 (rank : 570)	NC score	0.000718 (rank : 1296)
Query Neighborhood Hits	1031	Target Neighborhood Hits	906	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

AAK1_MOUSE
θ value	0.813845 (rank : 571)	NC score	0.042678 (rank : 959)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1051	Shared Neighborhood Hits	192
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ACRO_HUMAN
θ value	0.813845 (rank : 572)	NC score	0.001752 (rank : 1293)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	75
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

CCD1A_MOUSE
θ value	0.813845 (rank : 573)	NC score	0.018246 (rank : 1169)
Query Neighborhood Hits	1031	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

CD2_HUMAN
θ value	0.813845 (rank : 574)	NC score	0.092840 (rank : 452)
Query Neighborhood Hits	1031	Target Neighborhood Hits	504	Shared Neighborhood Hits	211
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CG1_HUMAN
θ value	0.813845 (rank : 575)	NC score	0.067165 (rank : 605)
Query Neighborhood Hits	1031	Target Neighborhood Hits	222	Shared Neighborhood Hits	105
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CO4A5_HUMAN
θ value	0.813845 (rank : 576)	NC score	0.046090 (rank : 935)
Query Neighborhood Hits	1031	Target Neighborhood Hits	383	Shared Neighborhood Hits	121
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CRKL_HUMAN
θ value	0.813845 (rank : 577)	NC score	0.037089 (rank : 1010)
Query Neighborhood Hits	1031	Target Neighborhood Hits	313	Shared Neighborhood Hits	66
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	0.813845 (rank : 578)	NC score	0.036772 (rank : 1014)
Query Neighborhood Hits	1031	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

DEN1A_MOUSE
θ value	0.813845 (rank : 579)	NC score	0.036188 (rank : 1020)
Query Neighborhood Hits	1031	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DYN2_HUMAN
θ value	0.813845 (rank : 580)	NC score	0.019466 (rank : 1163)
Query Neighborhood Hits	1031	Target Neighborhood Hits	112	Shared Neighborhood Hits	35
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

FGD1_MOUSE
θ value	0.813845 (rank : 581)	NC score	0.032031 (rank : 1066)
Query Neighborhood Hits	1031	Target Neighborhood Hits	387	Shared Neighborhood Hits	129
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

IF4G1_HUMAN
θ value	0.813845 (rank : 582)	NC score	0.063178 (rank : 648)
Query Neighborhood Hits	1031	Target Neighborhood Hits	347	Shared Neighborhood Hits	135
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

K1543_HUMAN
θ value	0.813845 (rank : 583)	NC score	0.087344 (rank : 472)
Query Neighborhood Hits	1031	Target Neighborhood Hits	435	Shared Neighborhood Hits	183
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LAD1_HUMAN
θ value	0.813845 (rank : 584)	NC score	0.069405 (rank : 587)
Query Neighborhood Hits	1031	Target Neighborhood Hits	441	Shared Neighborhood Hits	108
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MISS_MOUSE
θ value	0.813845 (rank : 585)	NC score	0.112904 (rank : 369)
Query Neighborhood Hits	1031	Target Neighborhood Hits	444	Shared Neighborhood Hits	218
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MMP9_HUMAN
θ value	0.813845 (rank : 586)	NC score	0.009585 (rank : 1243)
Query Neighborhood Hits	1031	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

NU214_HUMAN
θ value	0.813845 (rank : 587)	NC score	0.093483 (rank : 450)
Query Neighborhood Hits	1031	Target Neighborhood Hits	657	Shared Neighborhood Hits	175
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUMBL_HUMAN
θ value	0.813845 (rank : 588)	NC score	0.071375 (rank : 573)
Query Neighborhood Hits	1031	Target Neighborhood Hits	394	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

PELP1_MOUSE
θ value	0.813845 (rank : 589)	NC score	0.094070 (rank : 448)
Query Neighborhood Hits	1031	Target Neighborhood Hits	709	Shared Neighborhood Hits	233
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PRR13_HUMAN
θ value	0.813845 (rank : 590)	NC score	0.100746 (rank : 427)
Query Neighborhood Hits	1031	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RTN4_MOUSE
θ value	0.813845 (rank : 591)	NC score	0.059647 (rank : 717)
Query Neighborhood Hits	1031	Target Neighborhood Hits	341	Shared Neighborhood Hits	125
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SPR1A_MOUSE
θ value	0.813845 (rank : 592)	NC score	0.079973 (rank : 512)
Query Neighborhood Hits	1031	Target Neighborhood Hits	343	Shared Neighborhood Hits	168
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SRRM1_HUMAN
θ value	0.813845 (rank : 593)	NC score	0.152892 (rank : 317)
Query Neighborhood Hits	1031	Target Neighborhood Hits	690	Shared Neighborhood Hits	228
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SYNJ1_MOUSE
θ value	0.813845 (rank : 594)	NC score	0.082179 (rank : 505)
Query Neighborhood Hits	1031	Target Neighborhood Hits	516	Shared Neighborhood Hits	227
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TAU_MOUSE
θ value	0.813845 (rank : 595)	NC score	0.078049 (rank : 525)
Query Neighborhood Hits	1031	Target Neighborhood Hits	502	Shared Neighborhood Hits	188
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TNR3_HUMAN
θ value	0.813845 (rank : 596)	NC score	0.015051 (rank : 1194)
Query Neighborhood Hits	1031	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TXLNA_HUMAN
θ value	0.813845 (rank : 597)	NC score	0.037897 (rank : 1004)
Query Neighborhood Hits	1031	Target Neighborhood Hits	982	Shared Neighborhood Hits	142
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

WIRE_HUMAN
θ value	0.813845 (rank : 598)	NC score	0.149508 (rank : 320)
Query Neighborhood Hits	1031	Target Neighborhood Hits	329	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ZMYM3_HUMAN
θ value	0.813845 (rank : 599)	NC score	0.031500 (rank : 1070)
Query Neighborhood Hits	1031	Target Neighborhood Hits	223	Shared Neighborhood Hits	60
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

3BP1_MOUSE
θ value	1.06291 (rank : 600)	NC score	0.048458 (rank : 922)
Query Neighborhood Hits	1031	Target Neighborhood Hits	238	Shared Neighborhood Hits	90
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AIRE_MOUSE
θ value	1.06291 (rank : 601)	NC score	0.022213 (rank : 1136)
Query Neighborhood Hits	1031	Target Neighborhood Hits	196	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AMPH_HUMAN
θ value	1.06291 (rank : 602)	NC score	0.060137 (rank : 705)
Query Neighborhood Hits	1031	Target Neighborhood Hits	455	Shared Neighborhood Hits	130
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AP180_HUMAN
θ value	1.06291 (rank : 603)	NC score	0.049648 (rank : 917)
Query Neighborhood Hits	1031	Target Neighborhood Hits	183	Shared Neighborhood Hits	76
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

ATS14_HUMAN
θ value	1.06291 (rank : 604)	NC score	0.012353 (rank : 1221)
Query Neighborhood Hits	1031	Target Neighborhood Hits	382	Shared Neighborhood Hits	121
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

BAZ2A_MOUSE
θ value	1.06291 (rank : 605)	NC score	0.060695 (rank : 689)
Query Neighborhood Hits	1031	Target Neighborhood Hits	744	Shared Neighborhood Hits	218
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CT055_MOUSE
θ value	1.06291 (rank : 606)	NC score	0.040115 (rank : 980)
Query Neighborhood Hits	1031	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R184, Q8BQE5, Q8K024, Q8VEM7, Q9CU80	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55 homolog.

DIAP1_MOUSE
θ value	1.06291 (rank : 607)	NC score	0.072527 (rank : 563)
Query Neighborhood Hits	1031	Target Neighborhood Hits	839	Shared Neighborhood Hits	175
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

FXL19_MOUSE
θ value	1.06291 (rank : 608)	NC score	0.032933 (rank : 1059)
Query Neighborhood Hits	1031	Target Neighborhood Hits	217	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

GGA1_MOUSE
θ value	1.06291 (rank : 609)	NC score	0.021107 (rank : 1150)
Query Neighborhood Hits	1031	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GLIS3_MOUSE
θ value	1.06291 (rank : 610)	NC score	-0.008111 (rank : 1312)
Query Neighborhood Hits	1031	Target Neighborhood Hits	861	Shared Neighborhood Hits	107
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

IWS1_MOUSE
θ value	1.06291 (rank : 611)	NC score	0.082041 (rank : 506)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1258	Shared Neighborhood Hits	235
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

M3K11_HUMAN
θ value	1.06291 (rank : 612)	NC score	0.071995 (rank : 567)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1136	Shared Neighborhood Hits	196
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MEFV_MOUSE
θ value	1.06291 (rank : 613)	NC score	0.013374 (rank : 1209)
Query Neighborhood Hits	1031	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

PF21B_MOUSE
θ value	1.06291 (rank : 614)	NC score	0.039104 (rank : 993)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	97
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PIAS3_MOUSE
θ value	1.06291 (rank : 615)	NC score	0.007254 (rank : 1263)
Query Neighborhood Hits	1031	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

PKNX2_MOUSE
θ value	1.06291 (rank : 616)	NC score	0.007633 (rank : 1259)
Query Neighborhood Hits	1031	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

PRAX_HUMAN
θ value	1.06291 (rank : 617)	NC score	0.045287 (rank : 940)
Query Neighborhood Hits	1031	Target Neighborhood Hits	215	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRGC2_MOUSE
θ value	1.06291 (rank : 618)	NC score	0.030659 (rank : 1075)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PRPC_HUMAN
θ value	1.06291 (rank : 619)	NC score	0.078099 (rank : 523)
Query Neighborhood Hits	1031	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

RFIP1_HUMAN
θ value	1.06291 (rank : 620)	NC score	0.042483 (rank : 962)
Query Neighborhood Hits	1031	Target Neighborhood Hits	236	Shared Neighborhood Hits	71
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SARM1_HUMAN
θ value	1.06291 (rank : 621)	NC score	0.080565 (rank : 510)
Query Neighborhood Hits	1031	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

SF3A2_MOUSE
θ value	1.06291 (rank : 622)	NC score	0.108252 (rank : 392)
Query Neighborhood Hits	1031	Target Neighborhood Hits	247	Shared Neighborhood Hits	127
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SON_MOUSE
θ value	1.06291 (rank : 623)	NC score	0.114865 (rank : 363)
Query Neighborhood Hits	1031	Target Neighborhood Hits	957	Shared Neighborhood Hits	290
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPRR3_HUMAN
θ value	1.06291 (rank : 624)	NC score	0.057798 (rank : 762)
Query Neighborhood Hits	1031	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

WNK4_MOUSE
θ value	1.06291 (rank : 625)	NC score	0.051387 (rank : 882)
Query Neighborhood Hits	1031	Target Neighborhood Hits	961	Shared Neighborhood Hits	159
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZC3H6_HUMAN
θ value	1.06291 (rank : 626)	NC score	0.032644 (rank : 1062)
Query Neighborhood Hits	1031	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZN318_MOUSE
θ value	1.06291 (rank : 627)	NC score	0.038327 (rank : 1002)
Query Neighborhood Hits	1031	Target Neighborhood Hits	642	Shared Neighborhood Hits	115
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ZN447_HUMAN
θ value	1.06291 (rank : 628)	NC score	-0.004524 (rank : 1305)
Query Neighborhood Hits	1031	Target Neighborhood Hits	899	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

ABL1_HUMAN
θ value	1.38821 (rank : 629)	NC score	0.063953 (rank : 642)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1220	Shared Neighborhood Hits	198
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BRD4_MOUSE
θ value	1.38821 (rank : 630)	NC score	0.086433 (rank : 480)
Query Neighborhood Hits	1031	Target Neighborhood Hits	845	Shared Neighborhood Hits	235
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD8_MOUSE
θ value	1.38821 (rank : 631)	NC score	0.042221 (rank : 964)
Query Neighborhood Hits	1031	Target Neighborhood Hits	422	Shared Neighborhood Hits	98
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CAMKV_HUMAN
θ value	1.38821 (rank : 632)	NC score	0.035445 (rank : 1028)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1084	Shared Neighborhood Hits	180
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CDT1_HUMAN
θ value	1.38821 (rank : 633)	NC score	0.033375 (rank : 1055)
Query Neighborhood Hits	1031	Target Neighborhood Hits	92	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

CTDP1_HUMAN
θ value	1.38821 (rank : 634)	NC score	0.078116 (rank : 522)
Query Neighborhood Hits	1031	Target Neighborhood Hits	416	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DLG1_HUMAN
θ value	1.38821 (rank : 635)	NC score	0.006372 (rank : 1269)
Query Neighborhood Hits	1031	Target Neighborhood Hits	290	Shared Neighborhood Hits	45
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DMRTD_HUMAN
θ value	1.38821 (rank : 636)	NC score	0.067741 (rank : 599)
Query Neighborhood Hits	1031	Target Neighborhood Hits	216	Shared Neighborhood Hits	111
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

DTD1_MOUSE
θ value	1.38821 (rank : 637)	NC score	0.021622 (rank : 1144)
Query Neighborhood Hits	1031	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DD18, Q9CRE8, Q9CYL0, Q9D013, Q9D1G4	Gene names	Hars2
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

FOXO1_HUMAN
θ value	1.38821 (rank : 638)	NC score	0.007334 (rank : 1262)
Query Neighborhood Hits	1031	Target Neighborhood Hits	126	Shared Neighborhood Hits	20
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

GAK12_HUMAN
θ value	1.38821 (rank : 639)	NC score	0.034928 (rank : 1036)
Query Neighborhood Hits	1031	Target Neighborhood Hits	374	Shared Neighborhood Hits	168
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HDAC9_MOUSE
θ value	1.38821 (rank : 640)	NC score	0.023873 (rank : 1124)
Query Neighborhood Hits	1031	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

INSM1_HUMAN
θ value	1.38821 (rank : 641)	NC score	-0.003753 (rank : 1303)
Query Neighborhood Hits	1031	Target Neighborhood Hits	683	Shared Neighborhood Hits	41
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

LR37A_HUMAN
θ value	1.38821 (rank : 642)	NC score	0.056728 (rank : 782)
Query Neighborhood Hits	1031	Target Neighborhood Hits	720	Shared Neighborhood Hits	183
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MARK2_MOUSE
θ value	1.38821 (rank : 643)	NC score	0.039843 (rank : 984)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1018	Shared Neighborhood Hits	133
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

MBD6_HUMAN
θ value	1.38821 (rank : 644)	NC score	0.131652 (rank : 340)
Query Neighborhood Hits	1031	Target Neighborhood Hits	349	Shared Neighborhood Hits	162
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MINT_HUMAN
θ value	1.38821 (rank : 645)	NC score	0.074985 (rank : 540)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1291	Shared Neighborhood Hits	280
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL4_HUMAN
θ value	1.38821 (rank : 646)	NC score	0.109473 (rank : 380)
Query Neighborhood Hits	1031	Target Neighborhood Hits	722	Shared Neighborhood Hits	249
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MUC7_HUMAN
θ value	1.38821 (rank : 647)	NC score	0.147637 (rank : 323)
Query Neighborhood Hits	1031	Target Neighborhood Hits	538	Shared Neighborhood Hits	216
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PLXB1_MOUSE
θ value	1.38821 (rank : 648)	NC score	0.016658 (rank : 1180)
Query Neighborhood Hits	1031	Target Neighborhood Hits	259	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PRP5_HUMAN
θ value	1.38821 (rank : 649)	NC score	0.100309 (rank : 430)
Query Neighborhood Hits	1031	Target Neighborhood Hits	108	Shared Neighborhood Hits	54
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

RANB9_HUMAN
θ value	1.38821 (rank : 650)	NC score	0.049566 (rank : 918)
Query Neighborhood Hits	1031	Target Neighborhood Hits	179	Shared Neighborhood Hits	88
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RAPH1_HUMAN
θ value	1.38821 (rank : 651)	NC score	0.121148 (rank : 352)
Query Neighborhood Hits	1031	Target Neighborhood Hits	593	Shared Neighborhood Hits	257
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RARG1_MOUSE
θ value	1.38821 (rank : 652)	NC score	0.003204 (rank : 1286)
Query Neighborhood Hits	1031	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
θ value	1.38821 (rank : 653)	NC score	0.003190 (rank : 1287)
Query Neighborhood Hits	1031	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

REV1_MOUSE
θ value	1.38821 (rank : 654)	NC score	0.015728 (rank : 1189)
Query Neighborhood Hits	1031	Target Neighborhood Hits	67	Shared Neighborhood Hits	22
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

SEM6B_MOUSE
θ value	1.38821 (rank : 655)	NC score	0.014284 (rank : 1203)
Query Neighborhood Hits	1031	Target Neighborhood Hits	200	Shared Neighborhood Hits	68
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SNIP_MOUSE
θ value	1.38821 (rank : 656)	NC score	0.050246 (rank : 909)
Query Neighborhood Hits	1031	Target Neighborhood Hits	319	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SYN1_HUMAN
θ value	1.38821 (rank : 657)	NC score	0.103946 (rank : 414)
Query Neighborhood Hits	1031	Target Neighborhood Hits	419	Shared Neighborhood Hits	202
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TFE3_HUMAN
θ value	1.38821 (rank : 658)	NC score	0.007338 (rank : 1261)
Query Neighborhood Hits	1031	Target Neighborhood Hits	190	Shared Neighborhood Hits	21
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

ZAR1_MOUSE
θ value	1.38821 (rank : 659)	NC score	0.044811 (rank : 945)
Query Neighborhood Hits	1031	Target Neighborhood Hits	254	Shared Neighborhood Hits	72
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZN645_HUMAN
θ value	1.38821 (rank : 660)	NC score	0.056330 (rank : 791)
Query Neighborhood Hits	1031	Target Neighborhood Hits	265	Shared Neighborhood Hits	104
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ABCA7_HUMAN
θ value	1.81305 (rank : 661)	NC score	0.000643 (rank : 1297)
Query Neighborhood Hits	1031	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ADA19_MOUSE
θ value	1.81305 (rank : 662)	NC score	0.012183 (rank : 1222)
Query Neighborhood Hits	1031	Target Neighborhood Hits	315	Shared Neighborhood Hits	55
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

AHI1_MOUSE
θ value	1.81305 (rank : 663)	NC score	0.026888 (rank : 1105)
Query Neighborhood Hits	1031	Target Neighborhood Hits	496	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ATX2L_MOUSE
θ value	1.81305 (rank : 664)	NC score	0.070261 (rank : 582)
Query Neighborhood Hits	1031	Target Neighborhood Hits	401	Shared Neighborhood Hits	157
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

AUTS2_HUMAN
θ value	1.81305 (rank : 665)	NC score	0.069641 (rank : 586)
Query Neighborhood Hits	1031	Target Neighborhood Hits	342	Shared Neighborhood Hits	136
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BRD4_HUMAN
θ value	1.81305 (rank : 666)	NC score	0.073472 (rank : 555)
Query Neighborhood Hits	1031	Target Neighborhood Hits	851	Shared Neighborhood Hits	231
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CD2AP_HUMAN
θ value	1.81305 (rank : 667)	NC score	0.050946 (rank : 891)
Query Neighborhood Hits	1031	Target Neighborhood Hits	315	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CO5A1_MOUSE
θ value	1.81305 (rank : 668)	NC score	0.035100 (rank : 1032)
Query Neighborhood Hits	1031	Target Neighborhood Hits	419	Shared Neighborhood Hits	124
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CRTC1_HUMAN
θ value	1.81305 (rank : 669)	NC score	0.083132 (rank : 500)
Query Neighborhood Hits	1031	Target Neighborhood Hits	319	Shared Neighborhood Hits	167
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

DCC_HUMAN
θ value	1.81305 (rank : 670)	NC score	0.021139 (rank : 1149)
Query Neighborhood Hits	1031	Target Neighborhood Hits	583	Shared Neighborhood Hits	87
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DPOLL_MOUSE
θ value	1.81305 (rank : 671)	NC score	0.012969 (rank : 1212)
Query Neighborhood Hits	1031	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

FBN1_MOUSE
θ value	1.81305 (rank : 672)	NC score	0.050928 (rank : 892)
Query Neighborhood Hits	1031	Target Neighborhood Hits	563	Shared Neighborhood Hits	59
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

GA2L1_MOUSE
θ value	1.81305 (rank : 673)	NC score	0.032830 (rank : 1061)
Query Neighborhood Hits	1031	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GAB1_MOUSE
θ value	1.81305 (rank : 674)	NC score	0.026116 (rank : 1110)
Query Neighborhood Hits	1031	Target Neighborhood Hits	233	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAK6_HUMAN
θ value	1.81305 (rank : 675)	NC score	0.038691 (rank : 998)
Query Neighborhood Hits	1031	Target Neighborhood Hits	392	Shared Neighborhood Hits	189
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GTSE1_HUMAN
θ value	1.81305 (rank : 676)	NC score	0.058848 (rank : 731)
Query Neighborhood Hits	1031	Target Neighborhood Hits	193	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

HCN4_HUMAN
θ value	1.81305 (rank : 677)	NC score	0.033018 (rank : 1058)
Query Neighborhood Hits	1031	Target Neighborhood Hits	303	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

ITSN1_HUMAN
θ value	1.81305 (rank : 678)	NC score	0.043042 (rank : 956)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1757	Shared Neighborhood Hits	255
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	1.81305 (rank : 679)	NC score	0.045156 (rank : 942)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1669	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

LAMA5_HUMAN
θ value	1.81305 (rank : 680)	NC score	0.047095 (rank : 925)
Query Neighborhood Hits	1031	Target Neighborhood Hits	976	Shared Neighborhood Hits	139
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MAP1A_HUMAN
θ value	1.81305 (rank : 681)	NC score	0.074402 (rank : 544)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1626	Shared Neighborhood Hits	319
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAVS_MOUSE
θ value	1.81305 (rank : 682)	NC score	0.038690 (rank : 999)
Query Neighborhood Hits	1031	Target Neighborhood Hits	170	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

MK07_MOUSE
θ value	1.81305 (rank : 683)	NC score	0.041275 (rank : 968)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1054	Shared Neighborhood Hits	181
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MYST3_HUMAN
θ value	1.81305 (rank : 684)	NC score	0.048656 (rank : 920)
Query Neighborhood Hits	1031	Target Neighborhood Hits	772	Shared Neighborhood Hits	157
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NFRKB_MOUSE
θ value	1.81305 (rank : 685)	NC score	0.060333 (rank : 700)
Query Neighborhood Hits	1031	Target Neighborhood Hits	393	Shared Neighborhood Hits	145
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

OXRP_HUMAN
θ value	1.81305 (rank : 686)	NC score	0.013925 (rank : 1206)
Query Neighborhood Hits	1031	Target Neighborhood Hits	544	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PDC6I_MOUSE
θ value	1.81305 (rank : 687)	NC score	0.065566 (rank : 623)
Query Neighborhood Hits	1031	Target Neighborhood Hits	275	Shared Neighborhood Hits	108
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PI5PA_HUMAN
θ value	1.81305 (rank : 688)	NC score	0.113858 (rank : 367)
Query Neighborhood Hits	1031	Target Neighborhood Hits	749	Shared Neighborhood Hits	314
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRPE_HUMAN
θ value	1.81305 (rank : 689)	NC score	0.087322 (rank : 473)
Query Neighborhood Hits	1031	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PTN23_MOUSE
θ value	1.81305 (rank : 690)	NC score	0.053238 (rank : 849)
Query Neighborhood Hits	1031	Target Neighborhood Hits	726	Shared Neighborhood Hits	231
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SPEG_MOUSE
θ value	1.81305 (rank : 691)	NC score	0.050120 (rank : 914)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1959	Shared Neighborhood Hits	376
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRRM2_HUMAN
θ value	1.81305 (rank : 692)	NC score	0.135397 (rank : 337)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1296	Shared Neighborhood Hits	334
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYNPO_MOUSE
θ value	1.81305 (rank : 693)	NC score	0.042579 (rank : 960)
Query Neighborhood Hits	1031	Target Neighborhood Hits	242	Shared Neighborhood Hits	103
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

UROL1_MOUSE
θ value	1.81305 (rank : 694)	NC score	0.031115 (rank : 1072)
Query Neighborhood Hits	1031	Target Neighborhood Hits	235	Shared Neighborhood Hits	36
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ZAN_HUMAN
θ value	1.81305 (rank : 695)	NC score	0.057061 (rank : 776)
Query Neighborhood Hits	1031	Target Neighborhood Hits	679	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

AFF1_MOUSE
θ value	2.36792 (rank : 696)	NC score	0.060875 (rank : 684)
Query Neighborhood Hits	1031	Target Neighborhood Hits	351	Shared Neighborhood Hits	119
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

APC_HUMAN
θ value	2.36792 (rank : 697)	NC score	0.043334 (rank : 953)
Query Neighborhood Hits	1031	Target Neighborhood Hits	603	Shared Neighborhood Hits	123
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ARRD1_HUMAN
θ value	2.36792 (rank : 698)	NC score	0.021819 (rank : 1141)
Query Neighborhood Hits	1031	Target Neighborhood Hits	75	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ATX2L_HUMAN
θ value	2.36792 (rank : 699)	NC score	0.083176 (rank : 498)
Query Neighborhood Hits	1031	Target Neighborhood Hits	443	Shared Neighborhood Hits	171
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CABIN_HUMAN
θ value	2.36792 (rank : 700)	NC score	0.091936 (rank : 454)
Query Neighborhood Hits	1031	Target Neighborhood Hits	490	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CO8A1_MOUSE
θ value	2.36792 (rank : 701)	NC score	0.029027 (rank : 1088)
Query Neighborhood Hits	1031	Target Neighborhood Hits	251	Shared Neighborhood Hits	78
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

CS016_HUMAN
θ value	2.36792 (rank : 702)	NC score	0.108180 (rank : 395)
Query Neighborhood Hits	1031	Target Neighborhood Hits	310	Shared Neighborhood Hits	152
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

DAF1_MOUSE
θ value	2.36792 (rank : 703)	NC score	0.010587 (rank : 1232)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DDX24_MOUSE
θ value	2.36792 (rank : 704)	NC score	-0.001195 (rank : 1300)
Query Neighborhood Hits	1031	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DGCR8_HUMAN
θ value	2.36792 (rank : 705)	NC score	0.014076 (rank : 1205)
Query Neighborhood Hits	1031	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

E2AK4_HUMAN
θ value	2.36792 (rank : 706)	NC score	0.027821 (rank : 1096)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1012	Shared Neighborhood Hits	100
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

ENAH_MOUSE
θ value	2.36792 (rank : 707)	NC score	0.107393 (rank : 402)
Query Neighborhood Hits	1031	Target Neighborhood Hits	919	Shared Neighborhood Hits	258
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ETV7_HUMAN
θ value	2.36792 (rank : 708)	NC score	0.002207 (rank : 1292)
Query Neighborhood Hits	1031	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y603, Q9NZ65, Q9NZ66, Q9NZ68, Q9NZR8, Q9UNJ7, Q9Y5K4, Q9Y604	Gene names	ETV7, TEL2, TELB, TREF
Domain Architecture
Description	Transcription factor ETV7 (Transcription factor Tel-2) (ETS-related protein Tel2) (Tel-related Ets factor).

FBX46_MOUSE
θ value	2.36792 (rank : 709)	NC score	0.021940 (rank : 1140)
Query Neighborhood Hits	1031	Target Neighborhood Hits	139	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

FOG1_HUMAN
θ value	2.36792 (rank : 710)	NC score	0.014996 (rank : 1195)
Query Neighborhood Hits	1031	Target Neighborhood Hits	981	Shared Neighborhood Hits	148
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOG1_MOUSE
θ value	2.36792 (rank : 711)	NC score	0.022987 (rank : 1129)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1237	Shared Neighborhood Hits	246
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FREA_HUMAN
θ value	2.36792 (rank : 712)	NC score	0.012741 (rank : 1216)
Query Neighborhood Hits	1031	Target Neighborhood Hits	205	Shared Neighborhood Hits	75
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

GAK5_HUMAN
θ value	2.36792 (rank : 713)	NC score	0.039317 (rank : 991)
Query Neighborhood Hits	1031	Target Neighborhood Hits	429	Shared Neighborhood Hits	196
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GR65_HUMAN
θ value	2.36792 (rank : 714)	NC score	0.035681 (rank : 1025)
Query Neighborhood Hits	1031	Target Neighborhood Hits	148	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

IER5_MOUSE
θ value	2.36792 (rank : 715)	NC score	0.039462 (rank : 988)
Query Neighborhood Hits	1031	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IF4B_MOUSE
θ value	2.36792 (rank : 716)	NC score	0.029975 (rank : 1079)
Query Neighborhood Hits	1031	Target Neighborhood Hits	368	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IRAK2_HUMAN
θ value	2.36792 (rank : 717)	NC score	0.064909 (rank : 628)
Query Neighborhood Hits	1031	Target Neighborhood Hits	714	Shared Neighborhood Hits	86
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

KCNH6_HUMAN
θ value	2.36792 (rank : 718)	NC score	0.012796 (rank : 1214)
Query Neighborhood Hits	1031	Target Neighborhood Hits	222	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

LPP_HUMAN
θ value	2.36792 (rank : 719)	NC score	0.068582 (rank : 590)
Query Neighborhood Hits	1031	Target Neighborhood Hits	775	Shared Neighborhood Hits	275
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LPP_MOUSE
θ value	2.36792 (rank : 720)	NC score	0.020416 (rank : 1158)
Query Neighborhood Hits	1031	Target Neighborhood Hits	247	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

M4K3_HUMAN
θ value	2.36792 (rank : 721)	NC score	0.029850 (rank : 1080)
Query Neighborhood Hits	1031	Target Neighborhood Hits	857	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IVH8, Q8IVH7, Q9UDM5, Q9Y6R5	Gene names	MAP4K3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK).

MAGC1_HUMAN
θ value	2.36792 (rank : 722)	NC score	0.040326 (rank : 979)
Query Neighborhood Hits	1031	Target Neighborhood Hits	431	Shared Neighborhood Hits	147
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

NONO_MOUSE
θ value	2.36792 (rank : 723)	NC score	0.011862 (rank : 1224)
Query Neighborhood Hits	1031	Target Neighborhood Hits	444	Shared Neighborhood Hits	34
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

PAK4_HUMAN
θ value	2.36792 (rank : 724)	NC score	0.036413 (rank : 1017)
Query Neighborhood Hits	1031	Target Neighborhood Hits	924	Shared Neighborhood Hits	126
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PCD15_HUMAN
θ value	2.36792 (rank : 725)	NC score	0.005699 (rank : 1275)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	64
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCX3_MOUSE
θ value	2.36792 (rank : 726)	NC score	0.033205 (rank : 1057)
Query Neighborhood Hits	1031	Target Neighborhood Hits	134	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

PHF12_HUMAN
θ value	2.36792 (rank : 727)	NC score	0.018719 (rank : 1167)
Query Neighborhood Hits	1031	Target Neighborhood Hits	174	Shared Neighborhood Hits	45
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PRDM2_HUMAN
θ value	2.36792 (rank : 728)	NC score	0.016868 (rank : 1178)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1135	Shared Neighborhood Hits	179
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PTN22_MOUSE
θ value	2.36792 (rank : 729)	NC score	0.008988 (rank : 1249)
Query Neighborhood Hits	1031	Target Neighborhood Hits	179	Shared Neighborhood Hits	41
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

RPB1_HUMAN
θ value	2.36792 (rank : 730)	NC score	0.073686 (rank : 553)
Query Neighborhood Hits	1031	Target Neighborhood Hits	362	Shared Neighborhood Hits	132
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	2.36792 (rank : 731)	NC score	0.073662 (rank : 554)
Query Neighborhood Hits	1031	Target Neighborhood Hits	363	Shared Neighborhood Hits	133
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SYP2L_HUMAN
θ value	2.36792 (rank : 732)	NC score	0.062281 (rank : 661)
Query Neighborhood Hits	1031	Target Neighborhood Hits	400	Shared Neighborhood Hits	154
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TAF4_HUMAN
θ value	2.36792 (rank : 733)	NC score	0.130546 (rank : 342)
Query Neighborhood Hits	1031	Target Neighborhood Hits	687	Shared Neighborhood Hits	227
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TENS4_MOUSE
θ value	2.36792 (rank : 734)	NC score	0.028698 (rank : 1091)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

TPO_MOUSE
θ value	2.36792 (rank : 735)	NC score	0.057744 (rank : 765)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	125
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TPP2_MOUSE
θ value	2.36792 (rank : 736)	NC score	0.016142 (rank : 1182)
Query Neighborhood Hits	1031	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q64514	Gene names	Tpp2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

WASF2_MOUSE
θ value	2.36792 (rank : 737)	NC score	0.103847 (rank : 416)
Query Neighborhood Hits	1031	Target Neighborhood Hits	315	Shared Neighborhood Hits	178
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WDR33_HUMAN
θ value	2.36792 (rank : 738)	NC score	0.025125 (rank : 1118)
Query Neighborhood Hits	1031	Target Neighborhood Hits	638	Shared Neighborhood Hits	131
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ZBTB3_HUMAN
θ value	2.36792 (rank : 739)	NC score	-0.005980 (rank : 1310)
Query Neighborhood Hits	1031	Target Neighborhood Hits	910	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

ZDHC5_HUMAN
θ value	2.36792 (rank : 740)	NC score	0.044131 (rank : 949)
Query Neighborhood Hits	1031	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

AMPH_MOUSE
θ value	3.0926 (rank : 741)	NC score	0.048507 (rank : 921)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	79
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ARI1B_HUMAN
θ value	3.0926 (rank : 742)	NC score	0.079589 (rank : 514)
Query Neighborhood Hits	1031	Target Neighborhood Hits	567	Shared Neighborhood Hits	214
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARMX2_MOUSE
θ value	3.0926 (rank : 743)	NC score	0.053288 (rank : 848)
Query Neighborhood Hits	1031	Target Neighborhood Hits	349	Shared Neighborhood Hits	138
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

BRSK1_HUMAN
θ value	3.0926 (rank : 744)	NC score	0.036023 (rank : 1021)
Query Neighborhood Hits	1031	Target Neighborhood Hits	942	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

CBL_MOUSE
θ value	3.0926 (rank : 745)	NC score	0.037301 (rank : 1008)
Query Neighborhood Hits	1031	Target Neighborhood Hits	426	Shared Neighborhood Hits	117
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CN032_MOUSE
θ value	3.0926 (rank : 746)	NC score	0.106669 (rank : 408)
Query Neighborhood Hits	1031	Target Neighborhood Hits	233	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CO5A1_HUMAN
θ value	3.0926 (rank : 747)	NC score	0.037889 (rank : 1005)
Query Neighborhood Hits	1031	Target Neighborhood Hits	434	Shared Neighborhood Hits	125
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CQ028_MOUSE
θ value	3.0926 (rank : 748)	NC score	0.008141 (rank : 1254)
Query Neighborhood Hits	1031	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

CS021_HUMAN
θ value	3.0926 (rank : 749)	NC score	0.019058 (rank : 1164)
Query Neighborhood Hits	1031	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

CT151_HUMAN
θ value	3.0926 (rank : 750)	NC score	0.055968 (rank : 798)
Query Neighborhood Hits	1031	Target Neighborhood Hits	382	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

DGCR8_MOUSE
θ value	3.0926 (rank : 751)	NC score	0.014364 (rank : 1202)
Query Neighborhood Hits	1031	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

DLG5_HUMAN
θ value	3.0926 (rank : 752)	NC score	0.030884 (rank : 1073)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1088	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DOCK4_HUMAN
θ value	3.0926 (rank : 753)	NC score	0.021512 (rank : 1145)
Query Neighborhood Hits	1031	Target Neighborhood Hits	237	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DTD1_HUMAN
θ value	3.0926 (rank : 754)	NC score	0.021106 (rank : 1151)
Query Neighborhood Hits	1031	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TEA8, Q496D1, Q5W184, Q8WXU8, Q9BW67, Q9H464, Q9H474	Gene names	HARS2, C20orf88
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

EP400_MOUSE
θ value	3.0926 (rank : 755)	NC score	0.048990 (rank : 919)
Query Neighborhood Hits	1031	Target Neighborhood Hits	592	Shared Neighborhood Hits	192
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EVL_HUMAN
θ value	3.0926 (rank : 756)	NC score	0.051903 (rank : 874)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FBLI1_HUMAN
θ value	3.0926 (rank : 757)	NC score	0.014608 (rank : 1197)
Query Neighborhood Hits	1031	Target Neighborhood Hits	200	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

FMN2_MOUSE
θ value	3.0926 (rank : 758)	NC score	0.078202 (rank : 519)
Query Neighborhood Hits	1031	Target Neighborhood Hits	349	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FOXN1_MOUSE
θ value	3.0926 (rank : 759)	NC score	0.021388 (rank : 1147)
Query Neighborhood Hits	1031	Target Neighborhood Hits	300	Shared Neighborhood Hits	107
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

GAK10_HUMAN
θ value	3.0926 (rank : 760)	NC score	0.029793 (rank : 1081)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	134
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
θ value	3.0926 (rank : 761)	NC score	0.038950 (rank : 995)
Query Neighborhood Hits	1031	Target Neighborhood Hits	409	Shared Neighborhood Hits	188
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	3.0926 (rank : 762)	NC score	0.038413 (rank : 1001)
Query Neighborhood Hits	1031	Target Neighborhood Hits	406	Shared Neighborhood Hits	186
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	3.0926 (rank : 763)	NC score	0.039240 (rank : 992)
Query Neighborhood Hits	1031	Target Neighborhood Hits	415	Shared Neighborhood Hits	191
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK_HUMAN
θ value	3.0926 (rank : 764)	NC score	0.034962 (rank : 1034)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1028	Shared Neighborhood Hits	160
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GRAP_MOUSE
θ value	3.0926 (rank : 765)	NC score	0.035418 (rank : 1029)
Query Neighborhood Hits	1031	Target Neighborhood Hits	309	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

HIC1_HUMAN
θ value	3.0926 (rank : 766)	NC score	-0.010786 (rank : 1315)
Query Neighborhood Hits	1031	Target Neighborhood Hits	838	Shared Neighborhood Hits	58
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HS12B_HUMAN
θ value	3.0926 (rank : 767)	NC score	0.004899 (rank : 1280)
Query Neighborhood Hits	1031	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

JIP3_HUMAN
θ value	3.0926 (rank : 768)	NC score	0.046698 (rank : 927)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1039	Shared Neighborhood Hits	209
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

K0406_MOUSE
θ value	3.0926 (rank : 769)	NC score	0.007439 (rank : 1260)
Query Neighborhood Hits	1031	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V83, Q9CSY0	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA0406 homolog.

KTNB1_MOUSE
θ value	3.0926 (rank : 770)	NC score	-0.003545 (rank : 1302)
Query Neighborhood Hits	1031	Target Neighborhood Hits	356	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

MAST1_MOUSE
θ value	3.0926 (rank : 771)	NC score	0.034539 (rank : 1041)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1123	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST2_HUMAN
θ value	3.0926 (rank : 772)	NC score	0.034417 (rank : 1042)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1189	Shared Neighborhood Hits	182
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MGMT_MOUSE
θ value	3.0926 (rank : 773)	NC score	0.010876 (rank : 1231)
Query Neighborhood Hits	1031	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P26187, Q54A49	Gene names	Mgmt
Domain Architecture
Description	Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O- methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA- alkyltransferase).

MINT_MOUSE
θ value	3.0926 (rank : 774)	NC score	0.093569 (rank : 449)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1514	Shared Neighborhood Hits	374
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MK07_HUMAN
θ value	3.0926 (rank : 775)	NC score	0.042827 (rank : 958)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1087	Shared Neighborhood Hits	204
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MNT_HUMAN
θ value	3.0926 (rank : 776)	NC score	0.078179 (rank : 520)
Query Neighborhood Hits	1031	Target Neighborhood Hits	496	Shared Neighborhood Hits	191
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MUC2_HUMAN
θ value	3.0926 (rank : 777)	NC score	0.097463 (rank : 435)
Query Neighborhood Hits	1031	Target Neighborhood Hits	906	Shared Neighborhood Hits	244
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	3.0926 (rank : 778)	NC score	0.073977 (rank : 550)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1020	Shared Neighborhood Hits	208
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYO9B_HUMAN
θ value	3.0926 (rank : 779)	NC score	0.024934 (rank : 1119)
Query Neighborhood Hits	1031	Target Neighborhood Hits	641	Shared Neighborhood Hits	161
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NELFA_HUMAN
θ value	3.0926 (rank : 780)	NC score	0.062274 (rank : 662)
Query Neighborhood Hits	1031	Target Neighborhood Hits	161	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NFM_HUMAN
θ value	3.0926 (rank : 781)	NC score	0.033345 (rank : 1056)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1328	Shared Neighborhood Hits	192
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PO6F1_MOUSE
θ value	3.0926 (rank : 782)	NC score	0.019030 (rank : 1165)
Query Neighborhood Hits	1031	Target Neighborhood Hits	581	Shared Neighborhood Hits	127
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

PO6F2_MOUSE
θ value	3.0926 (rank : 783)	NC score	0.037036 (rank : 1011)
Query Neighborhood Hits	1031	Target Neighborhood Hits	639	Shared Neighborhood Hits	147
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

RASF7_MOUSE
θ value	3.0926 (rank : 784)	NC score	0.027140 (rank : 1104)
Query Neighborhood Hits	1031	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

RING1_MOUSE
θ value	3.0926 (rank : 785)	NC score	0.012926 (rank : 1213)
Query Neighborhood Hits	1031	Target Neighborhood Hits	220	Shared Neighborhood Hits	20
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

SC6A5_MOUSE
θ value	3.0926 (rank : 786)	NC score	0.001668 (rank : 1294)
Query Neighborhood Hits	1031	Target Neighborhood Hits	135	Shared Neighborhood Hits	40
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

SMRC2_MOUSE
θ value	3.0926 (rank : 787)	NC score	0.044386 (rank : 948)
Query Neighborhood Hits	1031	Target Neighborhood Hits	487	Shared Neighborhood Hits	123
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SPT5H_HUMAN
θ value	3.0926 (rank : 788)	NC score	0.073983 (rank : 549)
Query Neighborhood Hits	1031	Target Neighborhood Hits	436	Shared Neighborhood Hits	181
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	3.0926 (rank : 789)	NC score	0.074007 (rank : 548)
Query Neighborhood Hits	1031	Target Neighborhood Hits	437	Shared Neighborhood Hits	182
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SYNG_MOUSE
θ value	3.0926 (rank : 790)	NC score	0.027974 (rank : 1095)
Query Neighborhood Hits	1031	Target Neighborhood Hits	206	Shared Neighborhood Hits	75
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TACC3_HUMAN
θ value	3.0926 (rank : 791)	NC score	0.045807 (rank : 938)
Query Neighborhood Hits	1031	Target Neighborhood Hits	779	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TLE4_HUMAN
θ value	3.0926 (rank : 792)	NC score	0.017612 (rank : 1174)
Query Neighborhood Hits	1031	Target Neighborhood Hits	477	Shared Neighborhood Hits	107
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	3.0926 (rank : 793)	NC score	0.017805 (rank : 1171)
Query Neighborhood Hits	1031	Target Neighborhood Hits	482	Shared Neighborhood Hits	107
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TNC6B_HUMAN
θ value	3.0926 (rank : 794)	NC score	0.020535 (rank : 1157)
Query Neighborhood Hits	1031	Target Neighborhood Hits	256	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

TPP2_HUMAN
θ value	3.0926 (rank : 795)	NC score	0.014435 (rank : 1199)
Query Neighborhood Hits	1031	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	P29144	Gene names	TPP2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

TS13_MOUSE
θ value	3.0926 (rank : 796)	NC score	0.049827 (rank : 916)
Query Neighborhood Hits	1031	Target Neighborhood Hits	191	Shared Neighborhood Hits	72
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

WBS14_HUMAN
θ value	3.0926 (rank : 797)	NC score	0.070395 (rank : 580)
Query Neighborhood Hits	1031	Target Neighborhood Hits	273	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WNK4_HUMAN
θ value	3.0926 (rank : 798)	NC score	0.058758 (rank : 736)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1043	Shared Neighborhood Hits	202
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZC3H3_MOUSE
θ value	3.0926 (rank : 799)	NC score	0.025274 (rank : 1117)
Query Neighborhood Hits	1031	Target Neighborhood Hits	188	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZCH14_MOUSE
θ value	3.0926 (rank : 800)	NC score	0.035317 (rank : 1030)
Query Neighborhood Hits	1031	Target Neighborhood Hits	109	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ABL1_MOUSE
θ value	4.03905 (rank : 801)	NC score	0.064535 (rank : 637)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1178	Shared Neighborhood Hits	185
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

AFF3_HUMAN
θ value	4.03905 (rank : 802)	NC score	0.021022 (rank : 1152)
Query Neighborhood Hits	1031	Target Neighborhood Hits	190	Shared Neighborhood Hits	45
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

ARHG1_MOUSE
θ value	4.03905 (rank : 803)	NC score	0.018070 (rank : 1170)
Query Neighborhood Hits	1031	Target Neighborhood Hits	266	Shared Neighborhood Hits	88
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

B3A3_HUMAN
θ value	4.03905 (rank : 804)	NC score	0.005962 (rank : 1272)
Query Neighborhood Hits	1031	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

BAI1_HUMAN
θ value	4.03905 (rank : 805)	NC score	0.013558 (rank : 1208)
Query Neighborhood Hits	1031	Target Neighborhood Hits	375	Shared Neighborhood Hits	94
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAT3_MOUSE
θ value	4.03905 (rank : 806)	NC score	0.085097 (rank : 488)
Query Neighborhood Hits	1031	Target Neighborhood Hits	518	Shared Neighborhood Hits	211
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CARD6_HUMAN
θ value	4.03905 (rank : 807)	NC score	0.031621 (rank : 1069)
Query Neighborhood Hits	1031	Target Neighborhood Hits	145	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

CD008_HUMAN
θ value	4.03905 (rank : 808)	NC score	0.028080 (rank : 1094)
Query Neighborhood Hits	1031	Target Neighborhood Hits	330	Shared Neighborhood Hits	76
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CD248_MOUSE
θ value	4.03905 (rank : 809)	NC score	0.068155 (rank : 596)
Query Neighborhood Hits	1031	Target Neighborhood Hits	578	Shared Neighborhood Hits	182
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD2AP_MOUSE
θ value	4.03905 (rank : 810)	NC score	0.053604 (rank : 842)
Query Neighborhood Hits	1031	Target Neighborhood Hits	336	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2L7_HUMAN
θ value	4.03905 (rank : 811)	NC score	0.042873 (rank : 957)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1275	Shared Neighborhood Hits	224
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CDAN1_HUMAN
θ value	4.03905 (rank : 812)	NC score	0.040936 (rank : 971)
Query Neighborhood Hits	1031	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

CIC_MOUSE
θ value	4.03905 (rank : 813)	NC score	0.087941 (rank : 471)
Query Neighborhood Hits	1031	Target Neighborhood Hits	742	Shared Neighborhood Hits	270
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CNKR2_HUMAN
θ value	4.03905 (rank : 814)	NC score	0.046101 (rank : 934)
Query Neighborhood Hits	1031	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	4.03905 (rank : 815)	NC score	0.046077 (rank : 936)
Query Neighborhood Hits	1031	Target Neighborhood Hits	197	Shared Neighborhood Hits	34
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

COHA1_HUMAN
θ value	4.03905 (rank : 816)	NC score	0.040643 (rank : 973)
Query Neighborhood Hits	1031	Target Neighborhood Hits	400	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CU056_HUMAN
θ value	4.03905 (rank : 817)	NC score	0.009285 (rank : 1245)
Query Neighborhood Hits	1031	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0A9, Q9NSE5	Gene names	C21orf56
Domain Architecture	No domain graphic available
Description	Putative protein C21orf56.

CYTSA_HUMAN
θ value	4.03905 (rank : 818)	NC score	0.028260 (rank : 1093)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1138	Shared Neighborhood Hits	127
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DAAM1_HUMAN
θ value	4.03905 (rank : 819)	NC score	0.033942 (rank : 1048)
Query Neighborhood Hits	1031	Target Neighborhood Hits	483	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DAAM2_HUMAN
θ value	4.03905 (rank : 820)	NC score	0.029570 (rank : 1083)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	64
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ETV5_MOUSE
θ value	4.03905 (rank : 821)	NC score	0.021778 (rank : 1142)
Query Neighborhood Hits	1031	Target Neighborhood Hits	328	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

FMN1A_MOUSE
θ value	4.03905 (rank : 822)	NC score	0.078167 (rank : 521)
Query Neighborhood Hits	1031	Target Neighborhood Hits	423	Shared Neighborhood Hits	167
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	4.03905 (rank : 823)	NC score	0.074358 (rank : 545)
Query Neighborhood Hits	1031	Target Neighborhood Hits	447	Shared Neighborhood Hits	162
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FMNL_MOUSE
θ value	4.03905 (rank : 824)	NC score	0.057225 (rank : 772)
Query Neighborhood Hits	1031	Target Neighborhood Hits	428	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GLI2_HUMAN
θ value	4.03905 (rank : 825)	NC score	-0.004279 (rank : 1304)
Query Neighborhood Hits	1031	Target Neighborhood Hits	971	Shared Neighborhood Hits	127
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

GRAP_HUMAN
θ value	4.03905 (rank : 826)	NC score	0.037477 (rank : 1006)
Query Neighborhood Hits	1031	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

H10_HUMAN
θ value	4.03905 (rank : 827)	NC score	0.022125 (rank : 1139)
Query Neighborhood Hits	1031	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	P07305	Gene names	H1F0, H1FV
Domain Architecture
Description	Histone H1.0 (H1(0)) (Histone H1').

HGS_HUMAN
θ value	4.03905 (rank : 828)	NC score	0.046636 (rank : 928)
Query Neighborhood Hits	1031	Target Neighborhood Hits	517	Shared Neighborhood Hits	124
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HXD1_MOUSE
θ value	4.03905 (rank : 829)	NC score	-0.004770 (rank : 1307)
Query Neighborhood Hits	1031	Target Neighborhood Hits	381	Shared Neighborhood Hits	34
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

IQEC3_MOUSE
θ value	4.03905 (rank : 830)	NC score	0.034898 (rank : 1038)
Query Neighborhood Hits	1031	Target Neighborhood Hits	274	Shared Neighborhood Hits	102
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

JPH2_HUMAN
θ value	4.03905 (rank : 831)	NC score	0.064635 (rank : 636)
Query Neighborhood Hits	1031	Target Neighborhood Hits	639	Shared Neighborhood Hits	250
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K0310_HUMAN
θ value	4.03905 (rank : 832)	NC score	0.078063 (rank : 524)
Query Neighborhood Hits	1031	Target Neighborhood Hits	420	Shared Neighborhood Hits	174
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

LARP4_HUMAN
θ value	4.03905 (rank : 833)	NC score	0.027263 (rank : 1103)
Query Neighborhood Hits	1031	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LEG3_MOUSE
θ value	4.03905 (rank : 834)	NC score	0.015539 (rank : 1190)
Query Neighborhood Hits	1031	Target Neighborhood Hits	113	Shared Neighborhood Hits	35
SwissProt Accessions	P16110	Gene names	Lgals3
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-34 galactoside-binding lectin).

LIPA3_MOUSE
θ value	4.03905 (rank : 835)	NC score	0.034700 (rank : 1039)
Query Neighborhood Hits	1031	Target Neighborhood Hits	636	Shared Neighborhood Hits	80
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MA1B1_HUMAN
θ value	4.03905 (rank : 836)	NC score	0.020899 (rank : 1154)
Query Neighborhood Hits	1031	Target Neighborhood Hits	125	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MAGD1_HUMAN
θ value	4.03905 (rank : 837)	NC score	0.015800 (rank : 1187)
Query Neighborhood Hits	1031	Target Neighborhood Hits	130	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

MYO1F_HUMAN
θ value	4.03905 (rank : 838)	NC score	0.016045 (rank : 1184)
Query Neighborhood Hits	1031	Target Neighborhood Hits	275	Shared Neighborhood Hits	72
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

NRX2A_HUMAN
θ value	4.03905 (rank : 839)	NC score	0.048040 (rank : 923)
Query Neighborhood Hits	1031	Target Neighborhood Hits	614	Shared Neighborhood Hits	215
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	4.03905 (rank : 840)	NC score	0.058170 (rank : 751)
Query Neighborhood Hits	1031	Target Neighborhood Hits	481	Shared Neighborhood Hits	202
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

ODO2_HUMAN
θ value	4.03905 (rank : 841)	NC score	0.022127 (rank : 1138)
Query Neighborhood Hits	1031	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	P36957, Q9BQ32	Gene names	DLST, DLTS
Domain Architecture
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

RP1L1_HUMAN
θ value	4.03905 (rank : 842)	NC score	0.071310 (rank : 574)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1072	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SF04_MOUSE
θ value	4.03905 (rank : 843)	NC score	0.009773 (rank : 1242)
Query Neighborhood Hits	1031	Target Neighborhood Hits	95	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CH02, Q8R094	Gene names	Sf4
Domain Architecture	No domain graphic available
Description	Splicing factor 4.

SI1L3_HUMAN
θ value	4.03905 (rank : 844)	NC score	0.023899 (rank : 1123)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	110
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SMAP1_MOUSE
θ value	4.03905 (rank : 845)	NC score	0.066785 (rank : 608)
Query Neighborhood Hits	1031	Target Neighborhood Hits	120	Shared Neighborhood Hits	51
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMR1_MOUSE
θ value	4.03905 (rank : 846)	NC score	0.066024 (rank : 618)
Query Neighborhood Hits	1031	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	4.03905 (rank : 847)	NC score	0.082903 (rank : 501)
Query Neighborhood Hits	1031	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SRA1_HUMAN
θ value	4.03905 (rank : 848)	NC score	0.025455 (rank : 1115)
Query Neighborhood Hits	1031	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HD15, Q6NVU9, Q8IXM1, Q9HD13, Q9HD14	Gene names	SRA1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

TACC1_MOUSE
θ value	4.03905 (rank : 849)	NC score	0.039094 (rank : 994)
Query Neighborhood Hits	1031	Target Neighborhood Hits	667	Shared Neighborhood Hits	100
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TARA_MOUSE
θ value	4.03905 (rank : 850)	NC score	0.068496 (rank : 592)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1133	Shared Neighborhood Hits	225
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TGON2_MOUSE
θ value	4.03905 (rank : 851)	NC score	0.033588 (rank : 1052)
Query Neighborhood Hits	1031	Target Neighborhood Hits	277	Shared Neighborhood Hits	65
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TM108_HUMAN
θ value	4.03905 (rank : 852)	NC score	0.064747 (rank : 633)
Query Neighborhood Hits	1031	Target Neighborhood Hits	166	Shared Neighborhood Hits	88
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TROAP_HUMAN
θ value	4.03905 (rank : 853)	NC score	0.081979 (rank : 507)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	119
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

UBP8_HUMAN
θ value	4.03905 (rank : 854)	NC score	0.007641 (rank : 1258)
Query Neighborhood Hits	1031	Target Neighborhood Hits	751	Shared Neighborhood Hits	84
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

AKAP6_HUMAN
θ value	5.27518 (rank : 855)	NC score	0.016118 (rank : 1183)
Query Neighborhood Hits	1031	Target Neighborhood Hits	263	Shared Neighborhood Hits	30
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

ALKB3_MOUSE
θ value	5.27518 (rank : 856)	NC score	0.005765 (rank : 1274)
Query Neighborhood Hits	1031	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1E6	Gene names	Alkbh3
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 3.

BTBDC_HUMAN
θ value	5.27518 (rank : 857)	NC score	0.043209 (rank : 955)
Query Neighborhood Hits	1031	Target Neighborhood Hits	248	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

C1QC_HUMAN
θ value	5.27518 (rank : 858)	NC score	0.006191 (rank : 1271)
Query Neighborhood Hits	1031	Target Neighborhood Hits	124	Shared Neighborhood Hits	21
SwissProt Accessions	P02747, Q7Z502, Q96DL2, Q96H05	Gene names	C1QC, C1QG
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

CAC1B_MOUSE
θ value	5.27518 (rank : 859)	NC score	0.010287 (rank : 1237)
Query Neighborhood Hits	1031	Target Neighborhood Hits	351	Shared Neighborhood Hits	90
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CCD96_HUMAN
θ value	5.27518 (rank : 860)	NC score	0.042144 (rank : 965)
Query Neighborhood Hits	1031	Target Neighborhood Hits	595	Shared Neighborhood Hits	100
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CEND1_MOUSE
θ value	5.27518 (rank : 861)	NC score	0.069681 (rank : 584)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CENG3_HUMAN
θ value	5.27518 (rank : 862)	NC score	0.306462 (rank : 279)
Query Neighborhood Hits	1031	Target Neighborhood Hits	455	Shared Neighborhood Hits	239
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	5.27518 (rank : 863)	NC score	0.306400 (rank : 280)
Query Neighborhood Hits	1031	Target Neighborhood Hits	467	Shared Neighborhood Hits	243
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CF055_HUMAN
θ value	5.27518 (rank : 864)	NC score	0.008132 (rank : 1255)
Query Neighborhood Hits	1031	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP79, Q9H0R2, Q9H3K9, Q9P0Q0	Gene names	C6orf55
Domain Architecture
Description	Protein C6orf55 (Dopamine-responsive protein DRG-1).

CN032_HUMAN
θ value	5.27518 (rank : 865)	NC score	0.108756 (rank : 388)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	128
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CO5A2_HUMAN
θ value	5.27518 (rank : 866)	NC score	0.053557 (rank : 843)
Query Neighborhood Hits	1031	Target Neighborhood Hits	760	Shared Neighborhood Hits	211
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CRK_HUMAN
θ value	5.27518 (rank : 867)	NC score	0.036604 (rank : 1015)
Query Neighborhood Hits	1031	Target Neighborhood Hits	308	Shared Neighborhood Hits	64
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CTND2_HUMAN
θ value	5.27518 (rank : 868)	NC score	0.024556 (rank : 1121)
Query Neighborhood Hits	1031	Target Neighborhood Hits	333	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

DIAP1_HUMAN
θ value	5.27518 (rank : 869)	NC score	0.071534 (rank : 571)
Query Neighborhood Hits	1031	Target Neighborhood Hits	784	Shared Neighborhood Hits	178
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DRD4_HUMAN
θ value	5.27518 (rank : 870)	NC score	-0.008935 (rank : 1313)
Query Neighborhood Hits	1031	Target Neighborhood Hits	886	Shared Neighborhood Hits	43
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

E41L3_MOUSE
θ value	5.27518 (rank : 871)	NC score	0.004598 (rank : 1282)
Query Neighborhood Hits	1031	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

EPN3_MOUSE
θ value	5.27518 (rank : 872)	NC score	0.045838 (rank : 937)
Query Neighborhood Hits	1031	Target Neighborhood Hits	312	Shared Neighborhood Hits	129
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

FOXJ1_HUMAN
θ value	5.27518 (rank : 873)	NC score	0.000580 (rank : 1298)
Query Neighborhood Hits	1031	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q92949, O00630	Gene names	FOXJ1, FKHL13, HFH4
Domain Architecture
Description	Forkhead box protein J1 (Forkhead-related protein FKHL13) (Hepatocyte nuclear factor 3 forkhead homolog 4) (HFH-4).

GGN_HUMAN
θ value	5.27518 (rank : 874)	NC score	0.106983 (rank : 405)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	140
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GON4L_HUMAN
θ value	5.27518 (rank : 875)	NC score	0.042095 (rank : 966)
Query Neighborhood Hits	1031	Target Neighborhood Hits	555	Shared Neighborhood Hits	130
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HCN2_HUMAN
θ value	5.27518 (rank : 876)	NC score	0.041808 (rank : 967)
Query Neighborhood Hits	1031	Target Neighborhood Hits	369	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HSPB8_MOUSE
θ value	5.27518 (rank : 877)	NC score	0.003642 (rank : 1285)
Query Neighborhood Hits	1031	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JK92	Gene names	Hspb8, Cryac, Hsp22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22).

IRS1_MOUSE
θ value	5.27518 (rank : 878)	NC score	0.011681 (rank : 1225)
Query Neighborhood Hits	1031	Target Neighborhood Hits	112	Shared Neighborhood Hits	33
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

KI13B_HUMAN
θ value	5.27518 (rank : 879)	NC score	0.010301 (rank : 1235)
Query Neighborhood Hits	1031	Target Neighborhood Hits	492	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

MAP1B_HUMAN
θ value	5.27518 (rank : 880)	NC score	0.057075 (rank : 774)
Query Neighborhood Hits	1031	Target Neighborhood Hits	903	Shared Neighborhood Hits	155
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAVS_HUMAN
θ value	5.27518 (rank : 881)	NC score	0.064718 (rank : 634)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

ODO2_MOUSE
θ value	5.27518 (rank : 882)	NC score	0.029114 (rank : 1087)
Query Neighborhood Hits	1031	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

P2RX2_HUMAN
θ value	5.27518 (rank : 883)	NC score	0.014601 (rank : 1198)
Query Neighborhood Hits	1031	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

PELP1_HUMAN
θ value	5.27518 (rank : 884)	NC score	0.079386 (rank : 515)
Query Neighborhood Hits	1031	Target Neighborhood Hits	596	Shared Neighborhood Hits	157
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PER1_HUMAN
θ value	5.27518 (rank : 885)	NC score	0.044797 (rank : 946)
Query Neighborhood Hits	1031	Target Neighborhood Hits	215	Shared Neighborhood Hits	97
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER3_HUMAN
θ value	5.27518 (rank : 886)	NC score	0.057786 (rank : 763)
Query Neighborhood Hits	1031	Target Neighborhood Hits	479	Shared Neighborhood Hits	183
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PRG4_MOUSE
θ value	5.27518 (rank : 887)	NC score	0.123132 (rank : 349)
Query Neighborhood Hits	1031	Target Neighborhood Hits	624	Shared Neighborhood Hits	196
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

REST_MOUSE
θ value	5.27518 (rank : 888)	NC score	0.034920 (rank : 1037)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1506	Shared Neighborhood Hits	140
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RIN3_MOUSE
θ value	5.27518 (rank : 889)	NC score	0.060150 (rank : 704)
Query Neighborhood Hits	1031	Target Neighborhood Hits	239	Shared Neighborhood Hits	121
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RP3A_MOUSE
θ value	5.27518 (rank : 890)	NC score	0.029540 (rank : 1084)
Query Neighborhood Hits	1031	Target Neighborhood Hits	510	Shared Neighborhood Hits	163
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SFR15_HUMAN
θ value	5.27518 (rank : 891)	NC score	0.077864 (rank : 526)
Query Neighborhood Hits	1031	Target Neighborhood Hits	368	Shared Neighborhood Hits	127
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SH3K1_HUMAN
θ value	5.27518 (rank : 892)	NC score	0.055953 (rank : 799)
Query Neighborhood Hits	1031	Target Neighborhood Hits	341	Shared Neighborhood Hits	82
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	5.27518 (rank : 893)	NC score	0.052359 (rank : 861)
Query Neighborhood Hits	1031	Target Neighborhood Hits	332	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SIN3A_HUMAN
θ value	5.27518 (rank : 894)	NC score	0.033377 (rank : 1054)
Query Neighborhood Hits	1031	Target Neighborhood Hits	180	Shared Neighborhood Hits	89
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SMRC2_HUMAN
θ value	5.27518 (rank : 895)	NC score	0.045325 (rank : 939)
Query Neighborhood Hits	1031	Target Neighborhood Hits	499	Shared Neighborhood Hits	126
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SNPC4_MOUSE
θ value	5.27518 (rank : 896)	NC score	0.026591 (rank : 1107)
Query Neighborhood Hits	1031	Target Neighborhood Hits	237	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SNX18_MOUSE
θ value	5.27518 (rank : 897)	NC score	0.015215 (rank : 1191)
Query Neighborhood Hits	1031	Target Neighborhood Hits	198	Shared Neighborhood Hits	52
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SPN90_MOUSE
θ value	5.27518 (rank : 898)	NC score	0.023612 (rank : 1126)
Query Neighborhood Hits	1031	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SYN2_HUMAN
θ value	5.27518 (rank : 899)	NC score	0.052894 (rank : 855)
Query Neighborhood Hits	1031	Target Neighborhood Hits	213	Shared Neighborhood Hits	110
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

T22D4_HUMAN
θ value	5.27518 (rank : 900)	NC score	0.066512 (rank : 614)
Query Neighborhood Hits	1031	Target Neighborhood Hits	403	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TCF7_MOUSE
θ value	5.27518 (rank : 901)	NC score	0.018616 (rank : 1168)
Query Neighborhood Hits	1031	Target Neighborhood Hits	277	Shared Neighborhood Hits	98
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TESK1_MOUSE
θ value	5.27518 (rank : 902)	NC score	0.050297 (rank : 906)
Query Neighborhood Hits	1031	Target Neighborhood Hits	862	Shared Neighborhood Hits	108
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TPR_HUMAN
θ value	5.27518 (rank : 903)	NC score	0.035787 (rank : 1023)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1921	Shared Neighborhood Hits	162
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TTC17_HUMAN
θ value	5.27518 (rank : 904)	NC score	0.008525 (rank : 1251)
Query Neighborhood Hits	1031	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q96AE7	Gene names	TTC17
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 17 (TPR repeat protein 17).

US6NL_MOUSE
θ value	5.27518 (rank : 905)	NC score	0.012457 (rank : 1220)
Query Neighborhood Hits	1031	Target Neighborhood Hits	157	Shared Neighborhood Hits	43
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

VASP_HUMAN
θ value	5.27518 (rank : 906)	NC score	0.068309 (rank : 595)
Query Neighborhood Hits	1031	Target Neighborhood Hits	201	Shared Neighborhood Hits	99
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VAV3_HUMAN
θ value	5.27518 (rank : 907)	NC score	0.012670 (rank : 1218)
Query Neighborhood Hits	1031	Target Neighborhood Hits	398	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

WEE1_MOUSE
θ value	5.27518 (rank : 908)	NC score	0.033938 (rank : 1049)
Query Neighborhood Hits	1031	Target Neighborhood Hits	794	Shared Neighborhood Hits	82
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

ZYX_MOUSE
θ value	5.27518 (rank : 909)	NC score	0.036354 (rank : 1019)
Query Neighborhood Hits	1031	Target Neighborhood Hits	347	Shared Neighborhood Hits	95
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

AATK_MOUSE
θ value	6.88961 (rank : 910)	NC score	0.059282 (rank : 722)
Query Neighborhood Hits	1031	Target Neighborhood Hits	942	Shared Neighborhood Hits	139
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

AFF1_HUMAN
θ value	6.88961 (rank : 911)	NC score	0.075830 (rank : 534)
Query Neighborhood Hits	1031	Target Neighborhood Hits	506	Shared Neighborhood Hits	145
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AHTF1_MOUSE
θ value	6.88961 (rank : 912)	NC score	0.016683 (rank : 1179)
Query Neighborhood Hits	1031	Target Neighborhood Hits	176	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

AKAP9_HUMAN
θ value	6.88961 (rank : 913)	NC score	0.033841 (rank : 1050)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1710	Shared Neighborhood Hits	143
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ANR40_MOUSE
θ value	6.88961 (rank : 914)	NC score	0.531252 (rank : 219)
Query Neighborhood Hits	1031	Target Neighborhood Hits	228	Shared Neighborhood Hits	214
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANTR1_MOUSE
θ value	6.88961 (rank : 915)	NC score	0.032079 (rank : 1065)
Query Neighborhood Hits	1031	Target Neighborhood Hits	143	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ARHGG_MOUSE
θ value	6.88961 (rank : 916)	NC score	0.008344 (rank : 1252)
Query Neighborhood Hits	1031	Target Neighborhood Hits	152	Shared Neighborhood Hits	34
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

B4GN4_MOUSE
θ value	6.88961 (rank : 917)	NC score	0.009430 (rank : 1244)
Query Neighborhood Hits	1031	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BOC_HUMAN
θ value	6.88961 (rank : 918)	NC score	0.007074 (rank : 1265)
Query Neighborhood Hits	1031	Target Neighborhood Hits	543	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CAR10_MOUSE
θ value	6.88961 (rank : 919)	NC score	0.009794 (rank : 1241)
Query Neighborhood Hits	1031	Target Neighborhood Hits	407	Shared Neighborhood Hits	42
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

CASC3_MOUSE
θ value	6.88961 (rank : 920)	NC score	0.053542 (rank : 844)
Query Neighborhood Hits	1031	Target Neighborhood Hits	333	Shared Neighborhood Hits	120
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CCDC6_HUMAN
θ value	6.88961 (rank : 921)	NC score	0.034670 (rank : 1040)
Query Neighborhood Hits	1031	Target Neighborhood Hits	723	Shared Neighborhood Hits	95
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CO9A3_HUMAN
θ value	6.88961 (rank : 922)	NC score	0.026246 (rank : 1109)
Query Neighborhood Hits	1031	Target Neighborhood Hits	361	Shared Neighborhood Hits	99
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CP003_HUMAN
θ value	6.88961 (rank : 923)	NC score	0.010125 (rank : 1239)
Query Neighborhood Hits	1031	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

CRK_MOUSE
θ value	6.88961 (rank : 924)	NC score	0.035112 (rank : 1031)
Query Neighborhood Hits	1031	Target Neighborhood Hits	314	Shared Neighborhood Hits	67
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CUTL2_MOUSE
θ value	6.88961 (rank : 925)	NC score	0.027695 (rank : 1099)
Query Neighborhood Hits	1031	Target Neighborhood Hits	771	Shared Neighborhood Hits	119
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DAAM1_MOUSE
θ value	6.88961 (rank : 926)	NC score	0.030297 (rank : 1077)
Query Neighborhood Hits	1031	Target Neighborhood Hits	443	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DMPK_HUMAN
θ value	6.88961 (rank : 927)	NC score	0.020571 (rank : 1156)
Query Neighborhood Hits	1031	Target Neighborhood Hits	944	Shared Neighborhood Hits	92
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

DMPK_MOUSE
θ value	6.88961 (rank : 928)	NC score	0.021344 (rank : 1148)
Query Neighborhood Hits	1031	Target Neighborhood Hits	908	Shared Neighborhood Hits	88
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

DOK1_HUMAN
θ value	6.88961 (rank : 929)	NC score	0.010387 (rank : 1234)
Query Neighborhood Hits	1031	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

EFCB2_HUMAN
θ value	6.88961 (rank : 930)	NC score	0.001352 (rank : 1295)
Query Neighborhood Hits	1031	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VUJ9, Q59G23, Q9BS36	Gene names	EFCAB2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

ENV2_MOUSE
θ value	6.88961 (rank : 931)	NC score	0.006905 (rank : 1268)
Query Neighborhood Hits	1031	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

FOXGB_HUMAN
θ value	6.88961 (rank : 932)	NC score	0.000487 (rank : 1299)
Query Neighborhood Hits	1031	Target Neighborhood Hits	123	Shared Neighborhood Hits	26
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

FOXN1_HUMAN
θ value	6.88961 (rank : 933)	NC score	0.027738 (rank : 1097)
Query Neighborhood Hits	1031	Target Neighborhood Hits	377	Shared Neighborhood Hits	142
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

GCM1_MOUSE
θ value	6.88961 (rank : 934)	NC score	0.005099 (rank : 1279)
Query Neighborhood Hits	1031	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	P70348, O09103	Gene names	Gcm1, Gcma
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (mGCMa) (mGCM1).

GP112_HUMAN
θ value	6.88961 (rank : 935)	NC score	0.017776 (rank : 1172)
Query Neighborhood Hits	1031	Target Neighborhood Hits	441	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GRIN1_HUMAN
θ value	6.88961 (rank : 936)	NC score	0.089341 (rank : 461)
Query Neighborhood Hits	1031	Target Neighborhood Hits	681	Shared Neighborhood Hits	218
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

IQEC2_HUMAN
θ value	6.88961 (rank : 937)	NC score	0.035672 (rank : 1026)
Query Neighborhood Hits	1031	Target Neighborhood Hits	403	Shared Neighborhood Hits	143
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	6.88961 (rank : 938)	NC score	0.037290 (rank : 1009)
Query Neighborhood Hits	1031	Target Neighborhood Hits	417	Shared Neighborhood Hits	148
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

KCNC3_HUMAN
θ value	6.88961 (rank : 939)	NC score	0.005399 (rank : 1276)
Query Neighborhood Hits	1031	Target Neighborhood Hits	256	Shared Neighborhood Hits	78
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

LFNG_HUMAN
θ value	6.88961 (rank : 940)	NC score	0.002308 (rank : 1290)
Query Neighborhood Hits	1031	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NES3, O00589, Q96C39, Q9UJW5	Gene names	LFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LRSM1_HUMAN
θ value	6.88961 (rank : 941)	NC score	0.043656 (rank : 950)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1078	Shared Neighborhood Hits	99
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LTBP2_MOUSE
θ value	6.88961 (rank : 942)	NC score	0.054800 (rank : 824)
Query Neighborhood Hits	1031	Target Neighborhood Hits	617	Shared Neighborhood Hits	100
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MOR2A_MOUSE
θ value	6.88961 (rank : 943)	NC score	0.022225 (rank : 1135)
Query Neighborhood Hits	1031	Target Neighborhood Hits	220	Shared Neighborhood Hits	57
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

MTSS1_MOUSE
θ value	6.88961 (rank : 944)	NC score	0.074930 (rank : 541)
Query Neighborhood Hits	1031	Target Neighborhood Hits	592	Shared Neighborhood Hits	221
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MYCN_HUMAN
θ value	6.88961 (rank : 945)	NC score	0.008247 (rank : 1253)
Query Neighborhood Hits	1031	Target Neighborhood Hits	127	Shared Neighborhood Hits	24
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

NCK2_HUMAN
θ value	6.88961 (rank : 946)	NC score	0.026403 (rank : 1108)
Query Neighborhood Hits	1031	Target Neighborhood Hits	310	Shared Neighborhood Hits	62
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NONO_HUMAN
θ value	6.88961 (rank : 947)	NC score	0.010485 (rank : 1233)
Query Neighborhood Hits	1031	Target Neighborhood Hits	441	Shared Neighborhood Hits	32
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

PHLPP_HUMAN
θ value	6.88961 (rank : 948)	NC score	0.016031 (rank : 1185)
Query Neighborhood Hits	1031	Target Neighborhood Hits	604	Shared Neighborhood Hits	129
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PI5PA_MOUSE
θ value	6.88961 (rank : 949)	NC score	0.077291 (rank : 528)
Query Neighborhood Hits	1031	Target Neighborhood Hits	331	Shared Neighborhood Hits	165
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PMYT1_MOUSE
θ value	6.88961 (rank : 950)	NC score	0.029451 (rank : 1085)
Query Neighborhood Hits	1031	Target Neighborhood Hits	910	Shared Neighborhood Hits	131
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

PP1R8_HUMAN
θ value	6.88961 (rank : 951)	NC score	0.012752 (rank : 1215)
Query Neighborhood Hits	1031	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q12972, Q5TIF2, Q6PKF6, Q9UBH1, Q9UBZ0	Gene names	PPP1R8, ARD1, NIPP1
Domain Architecture
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)].

PRGC2_HUMAN
θ value	6.88961 (rank : 952)	NC score	0.029991 (rank : 1078)
Query Neighborhood Hits	1031	Target Neighborhood Hits	272	Shared Neighborhood Hits	76
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

RAI1_MOUSE
θ value	6.88961 (rank : 953)	NC score	0.045102 (rank : 943)
Query Neighborhood Hits	1031	Target Neighborhood Hits	344	Shared Neighborhood Hits	120
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RFIP3_HUMAN
θ value	6.88961 (rank : 954)	NC score	0.040610 (rank : 974)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1055	Shared Neighborhood Hits	152
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RKHD1_HUMAN
θ value	6.88961 (rank : 955)	NC score	0.022953 (rank : 1131)
Query Neighborhood Hits	1031	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RU1C_HUMAN
θ value	6.88961 (rank : 956)	NC score	0.050419 (rank : 903)
Query Neighborhood Hits	1031	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
θ value	6.88961 (rank : 957)	NC score	0.050624 (rank : 900)
Query Neighborhood Hits	1031	Target Neighborhood Hits	83	Shared Neighborhood Hits	44
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

SENP6_HUMAN
θ value	6.88961 (rank : 958)	NC score	0.004010 (rank : 1284)
Query Neighborhood Hits	1031	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SETBP_MOUSE
θ value	6.88961 (rank : 959)	NC score	0.045226 (rank : 941)
Query Neighborhood Hits	1031	Target Neighborhood Hits	352	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SF3A2_HUMAN
θ value	6.88961 (rank : 960)	NC score	0.102985 (rank : 421)
Query Neighborhood Hits	1031	Target Neighborhood Hits	263	Shared Neighborhood Hits	130
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SMG5_MOUSE
θ value	6.88961 (rank : 961)	NC score	0.006292 (rank : 1270)
Query Neighborhood Hits	1031	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

SOX13_MOUSE
θ value	6.88961 (rank : 962)	NC score	0.042531 (rank : 961)
Query Neighborhood Hits	1031	Target Neighborhood Hits	495	Shared Neighborhood Hits	168
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

STAM2_MOUSE
θ value	6.88961 (rank : 963)	NC score	0.041135 (rank : 969)
Query Neighborhood Hits	1031	Target Neighborhood Hits	285	Shared Neighborhood Hits	68
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

TB182_HUMAN
θ value	6.88961 (rank : 964)	NC score	0.070679 (rank : 579)
Query Neighborhood Hits	1031	Target Neighborhood Hits	414	Shared Neighborhood Hits	124
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TP53B_HUMAN
θ value	6.88961 (rank : 965)	NC score	0.034032 (rank : 1046)
Query Neighborhood Hits	1031	Target Neighborhood Hits	413	Shared Neighborhood Hits	79
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRPC3_HUMAN
θ value	6.88961 (rank : 966)	NC score	0.085806 (rank : 486)
Query Neighborhood Hits	1031	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPV3_HUMAN
θ value	6.88961 (rank : 967)	NC score	0.223081 (rank : 288)
Query Neighborhood Hits	1031	Target Neighborhood Hits	198	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

WASF2_HUMAN
θ value	6.88961 (rank : 968)	NC score	0.088228 (rank : 468)
Query Neighborhood Hits	1031	Target Neighborhood Hits	280	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

ZFHX2_HUMAN
θ value	6.88961 (rank : 969)	NC score	0.015757 (rank : 1188)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1178	Shared Neighborhood Hits	149
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

ZMYM3_MOUSE
θ value	6.88961 (rank : 970)	NC score	0.018966 (rank : 1166)
Query Neighborhood Hits	1031	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

AMOL2_HUMAN
θ value	8.99809 (rank : 971)	NC score	0.019698 (rank : 1160)
Query Neighborhood Hits	1031	Target Neighborhood Hits	603	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

ANKR9_MOUSE
θ value	8.99809 (rank : 972)	NC score	0.257109 (rank : 283)
Query Neighborhood Hits	1031	Target Neighborhood Hits	120	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANR40_HUMAN
θ value	8.99809 (rank : 973)	NC score	0.532967 (rank : 217)
Query Neighborhood Hits	1031	Target Neighborhood Hits	224	Shared Neighborhood Hits	211
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

AUXI_MOUSE
θ value	8.99809 (rank : 974)	NC score	0.007151 (rank : 1264)
Query Neighborhood Hits	1031	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

CASL_HUMAN
θ value	8.99809 (rank : 975)	NC score	0.047622 (rank : 924)
Query Neighborhood Hits	1031	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CDC20_HUMAN
θ value	8.99809 (rank : 976)	NC score	-0.002629 (rank : 1301)
Query Neighborhood Hits	1031	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

CE016_HUMAN
θ value	8.99809 (rank : 977)	NC score	0.014419 (rank : 1200)
Query Neighborhood Hits	1031	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

CEND_MOUSE
θ value	8.99809 (rank : 978)	NC score	0.027660 (rank : 1100)
Query Neighborhood Hits	1031	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JKC6, Q9DBA0	Gene names	Cend1, Bm88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

CN155_HUMAN
θ value	8.99809 (rank : 979)	NC score	0.114895 (rank : 362)
Query Neighborhood Hits	1031	Target Neighborhood Hits	385	Shared Neighborhood Hits	140
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CNTP1_MOUSE
θ value	8.99809 (rank : 980)	NC score	0.013144 (rank : 1211)
Query Neighborhood Hits	1031	Target Neighborhood Hits	183	Shared Neighborhood Hits	34
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CO8A1_HUMAN
θ value	8.99809 (rank : 981)	NC score	0.028740 (rank : 1090)
Query Neighborhood Hits	1031	Target Neighborhood Hits	288	Shared Neighborhood Hits	84
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

DLG3_HUMAN
θ value	8.99809 (rank : 982)	NC score	0.002380 (rank : 1289)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	8.99809 (rank : 983)	NC score	0.002505 (rank : 1288)
Query Neighborhood Hits	1031	Target Neighborhood Hits	274	Shared Neighborhood Hits	40
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

EP400_HUMAN
θ value	8.99809 (rank : 984)	NC score	0.046906 (rank : 926)
Query Neighborhood Hits	1031	Target Neighborhood Hits	556	Shared Neighborhood Hits	192
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EST1A_MOUSE
θ value	8.99809 (rank : 985)	NC score	0.008589 (rank : 1250)
Query Neighborhood Hits	1031	Target Neighborhood Hits	138	Shared Neighborhood Hits	21
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

ETV5_HUMAN
θ value	8.99809 (rank : 986)	NC score	0.009805 (rank : 1240)
Query Neighborhood Hits	1031	Target Neighborhood Hits	181	Shared Neighborhood Hits	59
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

FBLI1_MOUSE
θ value	8.99809 (rank : 987)	NC score	0.015074 (rank : 1193)
Query Neighborhood Hits	1031	Target Neighborhood Hits	228	Shared Neighborhood Hits	54
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

FGD1_HUMAN
θ value	8.99809 (rank : 988)	NC score	0.029623 (rank : 1082)
Query Neighborhood Hits	1031	Target Neighborhood Hits	367	Shared Neighborhood Hits	123
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FOXN4_HUMAN
θ value	8.99809 (rank : 989)	NC score	0.009097 (rank : 1247)
Query Neighborhood Hits	1031	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

GLIS1_MOUSE
θ value	8.99809 (rank : 990)	NC score	-0.013841 (rank : 1318)
Query Neighborhood Hits	1031	Target Neighborhood Hits	751	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

GLUD1_MOUSE
θ value	8.99809 (rank : 991)	NC score	0.009200 (rank : 1246)
Query Neighborhood Hits	1031	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

HCN2_MOUSE
θ value	8.99809 (rank : 992)	NC score	0.033946 (rank : 1047)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	131
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

K0423_HUMAN
θ value	8.99809 (rank : 993)	NC score	0.022547 (rank : 1133)
Query Neighborhood Hits	1031	Target Neighborhood Hits	171	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

K1914_MOUSE
θ value	8.99809 (rank : 994)	NC score	0.017504 (rank : 1175)
Query Neighborhood Hits	1031	Target Neighborhood Hits	216	Shared Neighborhood Hits	46
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

KCND1_MOUSE
θ value	8.99809 (rank : 995)	NC score	-0.004622 (rank : 1306)
Query Neighborhood Hits	1031	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KLF17_HUMAN
θ value	8.99809 (rank : 996)	NC score	-0.004779 (rank : 1308)
Query Neighborhood Hits	1031	Target Neighborhood Hits	882	Shared Neighborhood Hits	132
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

LDB3_MOUSE
θ value	8.99809 (rank : 997)	NC score	0.031700 (rank : 1068)
Query Neighborhood Hits	1031	Target Neighborhood Hits	510	Shared Neighborhood Hits	167
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LIMD1_MOUSE
θ value	8.99809 (rank : 998)	NC score	0.014387 (rank : 1201)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MLL2_HUMAN
θ value	8.99809 (rank : 999)	NC score	0.121331 (rank : 351)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1788	Shared Neighborhood Hits	418
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MORN1_HUMAN
θ value	8.99809 (rank : 1000)	NC score	0.012536 (rank : 1219)
Query Neighborhood Hits	1031	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T089, Q8WW30, Q9H852	Gene names	MORN1
Domain Architecture	No domain graphic available
Description	MORN repeat-containing protein 1.

MTR1L_MOUSE
θ value	8.99809 (rank : 1001)	NC score	-0.017580 (rank : 1319)
Query Neighborhood Hits	1031	Target Neighborhood Hits	903	Shared Neighborhood Hits	13
SwissProt Accessions	O88495	Gene names	Gpr50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NCOR2_HUMAN
θ value	8.99809 (rank : 1002)	NC score	0.078404 (rank : 518)
Query Neighborhood Hits	1031	Target Neighborhood Hits	870	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NELFA_MOUSE
θ value	8.99809 (rank : 1003)	NC score	0.061410 (rank : 675)
Query Neighborhood Hits	1031	Target Neighborhood Hits	195	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NET1_HUMAN
θ value	8.99809 (rank : 1004)	NC score	0.011287 (rank : 1228)
Query Neighborhood Hits	1031	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NIPBL_HUMAN
θ value	8.99809 (rank : 1005)	NC score	0.057471 (rank : 771)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1311	Shared Neighborhood Hits	213
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NTBP1_MOUSE
θ value	8.99809 (rank : 1006)	NC score	0.020996 (rank : 1153)
Query Neighborhood Hits	1031	Target Neighborhood Hits	528	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

PALB2_MOUSE
θ value	8.99809 (rank : 1007)	NC score	0.019667 (rank : 1161)
Query Neighborhood Hits	1031	Target Neighborhood Hits	133	Shared Neighborhood Hits	36
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PDCD7_MOUSE
θ value	8.99809 (rank : 1008)	NC score	0.040112 (rank : 981)
Query Neighborhood Hits	1031	Target Neighborhood Hits	214	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PML_HUMAN
θ value	8.99809 (rank : 1009)	NC score	0.011420 (rank : 1227)
Query Neighborhood Hits	1031	Target Neighborhood Hits	248	Shared Neighborhood Hits	39
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PP1R8_MOUSE
θ value	8.99809 (rank : 1010)	NC score	0.010293 (rank : 1236)
Query Neighborhood Hits	1031	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

PYGO2_HUMAN
θ value	8.99809 (rank : 1011)	NC score	0.054735 (rank : 825)
Query Neighborhood Hits	1031	Target Neighborhood Hits	189	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RBM16_HUMAN
θ value	8.99809 (rank : 1012)	NC score	0.039697 (rank : 987)
Query Neighborhood Hits	1031	Target Neighborhood Hits	300	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RIMB1_MOUSE
θ value	8.99809 (rank : 1013)	NC score	0.039771 (rank : 985)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1376	Shared Neighborhood Hits	212
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RUSC2_MOUSE
θ value	8.99809 (rank : 1014)	NC score	0.036511 (rank : 1016)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	110
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SGIP1_MOUSE
θ value	8.99809 (rank : 1015)	NC score	0.071795 (rank : 568)
Query Neighborhood Hits	1031	Target Neighborhood Hits	180	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SMAL1_HUMAN
θ value	8.99809 (rank : 1016)	NC score	0.011069 (rank : 1230)
Query Neighborhood Hits	1031	Target Neighborhood Hits	174	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SRBP1_HUMAN
θ value	8.99809 (rank : 1017)	NC score	0.040011 (rank : 983)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

STABP_MOUSE
θ value	8.99809 (rank : 1018)	NC score	0.007831 (rank : 1257)
Query Neighborhood Hits	1031	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

STK36_HUMAN
θ value	8.99809 (rank : 1019)	NC score	0.034972 (rank : 1033)
Query Neighborhood Hits	1031	Target Neighborhood Hits	896	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

SYN2_MOUSE
θ value	8.99809 (rank : 1020)	NC score	0.043512 (rank : 952)
Query Neighborhood Hits	1031	Target Neighborhood Hits	183	Shared Neighborhood Hits	98
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

SYYC_MOUSE
θ value	8.99809 (rank : 1021)	NC score	0.004537 (rank : 1283)
Query Neighborhood Hits	1031	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183	Gene names	Yars
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

TRRAP_HUMAN
θ value	8.99809 (rank : 1022)	NC score	0.010190 (rank : 1238)
Query Neighborhood Hits	1031	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

TXLNA_MOUSE
θ value	8.99809 (rank : 1023)	NC score	0.031435 (rank : 1071)
Query Neighborhood Hits	1031	Target Neighborhood Hits	846	Shared Neighborhood Hits	94
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

UBP53_MOUSE
θ value	8.99809 (rank : 1024)	NC score	0.015156 (rank : 1192)
Query Neighborhood Hits	1031	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

VAV3_MOUSE
θ value	8.99809 (rank : 1025)	NC score	0.011672 (rank : 1226)
Query Neighborhood Hits	1031	Target Neighborhood Hits	404	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

WNK1_MOUSE
θ value	8.99809 (rank : 1026)	NC score	0.050252 (rank : 908)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1179	Shared Neighborhood Hits	178
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

YETS2_MOUSE
θ value	8.99809 (rank : 1027)	NC score	0.030348 (rank : 1076)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	82
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZCH14_HUMAN
θ value	8.99809 (rank : 1028)	NC score	0.025579 (rank : 1114)
Query Neighborhood Hits	1031	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZDHC8_MOUSE
θ value	8.99809 (rank : 1029)	NC score	0.046108 (rank : 933)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	91
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ZN174_HUMAN
θ value	8.99809 (rank : 1030)	NC score	-0.013218 (rank : 1317)
Query Neighborhood Hits	1031	Target Neighborhood Hits	744	Shared Neighborhood Hits	40
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).

ZN687_MOUSE
θ value	8.99809 (rank : 1031)	NC score	0.002264 (rank : 1291)
Query Neighborhood Hits	1031	Target Neighborhood Hits	913	Shared Neighborhood Hits	126
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AATK_HUMAN
θ value	θ > 10 (rank : 1032)	NC score	0.066384 (rank : 615)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1243	Shared Neighborhood Hits	270
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ABI2_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.051642 (rank : 876)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABL2_HUMAN
θ value	θ > 10 (rank : 1034)	NC score	0.057780 (rank : 764)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1045	Shared Neighborhood Hits	129
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABTB1_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.229231 (rank : 286)
Query Neighborhood Hits	1031	Target Neighborhood Hits	325	Shared Neighborhood Hits	160
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	θ > 10 (rank : 1036)	NC score	0.270556 (rank : 281)
Query Neighborhood Hits	1031	Target Neighborhood Hits	349	Shared Neighborhood Hits	176
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ACINU_MOUSE
θ value	θ > 10 (rank : 1037)	NC score	0.056443 (rank : 789)
Query Neighborhood Hits	1031	Target Neighborhood Hits	712	Shared Neighborhood Hits	143
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACK1_HUMAN
θ value	θ > 10 (rank : 1038)	NC score	0.074251 (rank : 547)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1140	Shared Neighborhood Hits	261
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	θ > 10 (rank : 1039)	NC score	0.073687 (rank : 552)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1080	Shared Neighborhood Hits	237
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ALEX_MOUSE
θ value	θ > 10 (rank : 1040)	NC score	0.073197 (rank : 557)
Query Neighborhood Hits	1031	Target Neighborhood Hits	197	Shared Neighborhood Hits	95
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALK_HUMAN
θ value	θ > 10 (rank : 1041)	NC score	0.057917 (rank : 758)
Query Neighborhood Hits	1031	Target Neighborhood Hits	795	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 1042)	NC score	0.058524 (rank : 743)
Query Neighborhood Hits	1031	Target Neighborhood Hits	811	Shared Neighborhood Hits	87
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

AMOT_HUMAN
θ value	θ > 10 (rank : 1043)	NC score	0.050731 (rank : 896)
Query Neighborhood Hits	1031	Target Neighborhood Hits	712	Shared Neighborhood Hits	155
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

AN13D_HUMAN
θ value	θ > 10 (rank : 1044)	NC score	0.053873 (rank : 838)
Query Neighborhood Hits	1031	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

AN13D_MOUSE
θ value	θ > 10 (rank : 1045)	NC score	0.054026 (rank : 835)
Query Neighborhood Hits	1031	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

ANKF1_HUMAN
θ value	θ > 10 (rank : 1046)	NC score	0.128272 (rank : 343)
Query Neighborhood Hits	1031	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 1047)	NC score	0.206721 (rank : 294)
Query Neighborhood Hits	1031	Target Neighborhood Hits	99	Shared Neighborhood Hits	97
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANPRA_MOUSE
θ value	θ > 10 (rank : 1048)	NC score	0.052089 (rank : 869)
Query Neighborhood Hits	1031	Target Neighborhood Hits	600	Shared Neighborhood Hits	69
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRB_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.053050 (rank : 852)
Query Neighborhood Hits	1031	Target Neighborhood Hits	646	Shared Neighborhood Hits	69
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	θ > 10 (rank : 1050)	NC score	0.053891 (rank : 837)
Query Neighborhood Hits	1031	Target Neighborhood Hits	607	Shared Neighborhood Hits	65
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANR45_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.542860 (rank : 213)
Query Neighborhood Hits	1031	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ARAF_HUMAN
θ value	θ > 10 (rank : 1052)	NC score	0.055374 (rank : 810)
Query Neighborhood Hits	1031	Target Neighborhood Hits	924	Shared Neighborhood Hits	101
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	θ > 10 (rank : 1053)	NC score	0.054358 (rank : 830)
Query Neighborhood Hits	1031	Target Neighborhood Hits	874	Shared Neighborhood Hits	85
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

ARFG1_HUMAN
θ value	θ > 10 (rank : 1054)	NC score	0.051608 (rank : 877)
Query Neighborhood Hits	1031	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_MOUSE
θ value	θ > 10 (rank : 1055)	NC score	0.052038 (rank : 871)
Query Neighborhood Hits	1031	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
θ value	θ > 10 (rank : 1056)	NC score	0.051469 (rank : 880)
Query Neighborhood Hits	1031	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 1057)	NC score	0.051965 (rank : 872)
Query Neighborhood Hits	1031	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ATX2_HUMAN
θ value	θ > 10 (rank : 1058)	NC score	0.064534 (rank : 638)
Query Neighborhood Hits	1031	Target Neighborhood Hits	375	Shared Neighborhood Hits	135
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX7_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.055444 (rank : 809)
Query Neighborhood Hits	1031	Target Neighborhood Hits	351	Shared Neighborhood Hits	158
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

ATX7_MOUSE
θ value	θ > 10 (rank : 1060)	NC score	0.053986 (rank : 836)
Query Neighborhood Hits	1031	Target Neighborhood Hits	328	Shared Neighborhood Hits	171
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BAG3_HUMAN
θ value	θ > 10 (rank : 1061)	NC score	0.070164 (rank : 583)
Query Neighborhood Hits	1031	Target Neighborhood Hits	314	Shared Neighborhood Hits	140
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BASP_HUMAN
θ value	θ > 10 (rank : 1062)	NC score	0.092759 (rank : 453)
Query Neighborhood Hits	1031	Target Neighborhood Hits	321	Shared Neighborhood Hits	100
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 1063)	NC score	0.107483 (rank : 401)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	94
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT3_HUMAN
θ value	θ > 10 (rank : 1064)	NC score	0.079141 (rank : 516)
Query Neighborhood Hits	1031	Target Neighborhood Hits	490	Shared Neighborhood Hits	204
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT4_HUMAN
θ value	θ > 10 (rank : 1065)	NC score	0.212296 (rank : 292)
Query Neighborhood Hits	1031	Target Neighborhood Hits	157	Shared Neighborhood Hits	111
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
θ value	θ > 10 (rank : 1066)	NC score	0.243330 (rank : 284)
Query Neighborhood Hits	1031	Target Neighborhood Hits	171	Shared Neighborhood Hits	125
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BLK_HUMAN
θ value	θ > 10 (rank : 1067)	NC score	0.059020 (rank : 726)
Query Neighborhood Hits	1031	Target Neighborhood Hits	994	Shared Neighborhood Hits	116
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 1068)	NC score	0.058011 (rank : 755)
Query Neighborhood Hits	1031	Target Neighborhood Hits	992	Shared Neighborhood Hits	112
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BMPR2_HUMAN
θ value	θ > 10 (rank : 1069)	NC score	0.051011 (rank : 890)
Query Neighborhood Hits	1031	Target Neighborhood Hits	736	Shared Neighborhood Hits	74
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

BMPR2_MOUSE
θ value	θ > 10 (rank : 1070)	NC score	0.051152 (rank : 887)
Query Neighborhood Hits	1031	Target Neighborhood Hits	738	Shared Neighborhood Hits	77
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

BMX_HUMAN
θ value	θ > 10 (rank : 1071)	NC score	0.056837 (rank : 779)
Query Neighborhood Hits	1031	Target Neighborhood Hits	942	Shared Neighborhood Hits	96
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 1072)	NC score	0.057197 (rank : 773)
Query Neighborhood Hits	1031	Target Neighborhood Hits	912	Shared Neighborhood Hits	93
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BRAF1_HUMAN
θ value	θ > 10 (rank : 1073)	NC score	0.056559 (rank : 786)
Query Neighborhood Hits	1031	Target Neighborhood Hits	883	Shared Neighborhood Hits	91
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BTK_HUMAN
θ value	θ > 10 (rank : 1074)	NC score	0.061740 (rank : 669)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1026	Shared Neighborhood Hits	126
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 1075)	NC score	0.061175 (rank : 677)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1017	Shared Neighborhood Hits	125
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CCNK_MOUSE
θ value	θ > 10 (rank : 1076)	NC score	0.086909 (rank : 478)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	159
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CDN1C_HUMAN
θ value	θ > 10 (rank : 1077)	NC score	0.084104 (rank : 496)
Query Neighborhood Hits	1031	Target Neighborhood Hits	168	Shared Neighborhood Hits	94
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CENA1_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.055733 (rank : 804)
Query Neighborhood Hits	1031	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 1079)	NC score	0.051239 (rank : 885)
Query Neighborhood Hits	1031	Target Neighborhood Hits	83	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 1080)	NC score	0.051378 (rank : 883)
Query Neighborhood Hits	1031	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CEND1_HUMAN
θ value	θ > 10 (rank : 1081)	NC score	0.075185 (rank : 538)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CI079_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.052437 (rank : 857)
Query Neighborhood Hits	1031	Target Neighborhood Hits	288	Shared Neighborhood Hits	114
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CIZ1_HUMAN
θ value	θ > 10 (rank : 1083)	NC score	0.074258 (rank : 546)
Query Neighborhood Hits	1031	Target Neighborhood Hits	359	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CNOT3_HUMAN
θ value	θ > 10 (rank : 1084)	NC score	0.062224 (rank : 663)
Query Neighborhood Hits	1031	Target Neighborhood Hits	425	Shared Neighborhood Hits	115
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	θ > 10 (rank : 1085)	NC score	0.062342 (rank : 659)
Query Neighborhood Hits	1031	Target Neighborhood Hits	504	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO002_HUMAN
θ value	θ > 10 (rank : 1086)	NC score	0.053793 (rank : 839)
Query Neighborhood Hits	1031	Target Neighborhood Hits	387	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.066176 (rank : 616)
Query Neighborhood Hits	1031	Target Neighborhood Hits	264	Shared Neighborhood Hits	131
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CRSP2_HUMAN
θ value	θ > 10 (rank : 1088)	NC score	0.068139 (rank : 597)
Query Neighborhood Hits	1031	Target Neighborhood Hits	380	Shared Neighborhood Hits	167
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CRTC1_MOUSE
θ value	θ > 10 (rank : 1089)	NC score	0.051039 (rank : 889)
Query Neighborhood Hits	1031	Target Neighborhood Hits	230	Shared Neighborhood Hits	105
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CSF1_HUMAN
θ value	θ > 10 (rank : 1090)	NC score	0.071772 (rank : 569)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	116
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CSK_HUMAN
θ value	θ > 10 (rank : 1091)	NC score	0.057071 (rank : 775)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	108
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 1092)	NC score	0.056027 (rank : 797)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	108
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CU081_HUMAN
θ value	θ > 10 (rank : 1093)	NC score	0.088623 (rank : 464)
Query Neighborhood Hits	1031	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DDR1_HUMAN
θ value	θ > 10 (rank : 1094)	NC score	0.060658 (rank : 692)
Query Neighborhood Hits	1031	Target Neighborhood Hits	819	Shared Neighborhood Hits	85
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 1095)	NC score	0.060323 (rank : 701)
Query Neighborhood Hits	1031	Target Neighborhood Hits	818	Shared Neighborhood Hits	85
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 1096)	NC score	0.058572 (rank : 742)
Query Neighborhood Hits	1031	Target Neighborhood Hits	818	Shared Neighborhood Hits	78
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 1097)	NC score	0.058179 (rank : 748)
Query Neighborhood Hits	1031	Target Neighborhood Hits	813	Shared Neighborhood Hits	80
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DGKK_HUMAN
θ value	θ > 10 (rank : 1098)	NC score	0.084773 (rank : 494)
Query Neighborhood Hits	1031	Target Neighborhood Hits	378	Shared Neighborhood Hits	145
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIDO1_HUMAN
θ value	θ > 10 (rank : 1099)	NC score	0.088561 (rank : 465)
Query Neighborhood Hits	1031	Target Neighborhood Hits	960	Shared Neighborhood Hits	257
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DNER_HUMAN
θ value	θ > 10 (rank : 1100)	NC score	0.050641 (rank : 899)
Query Neighborhood Hits	1031	Target Neighborhood Hits	460	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 1101)	NC score	0.050743 (rank : 895)
Query Neighborhood Hits	1031	Target Neighborhood Hits	413	Shared Neighborhood Hits	36
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DOT1L_HUMAN
θ value	θ > 10 (rank : 1102)	NC score	0.067024 (rank : 607)
Query Neighborhood Hits	1031	Target Neighborhood Hits	660	Shared Neighborhood Hits	173
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EFS_HUMAN
θ value	θ > 10 (rank : 1103)	NC score	0.060440 (rank : 697)
Query Neighborhood Hits	1031	Target Neighborhood Hits	348	Shared Neighborhood Hits	141
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	θ > 10 (rank : 1104)	NC score	0.063786 (rank : 643)
Query Neighborhood Hits	1031	Target Neighborhood Hits	389	Shared Neighborhood Hits	151
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

EGFR_HUMAN
θ value	θ > 10 (rank : 1105)	NC score	0.059927 (rank : 710)
Query Neighborhood Hits	1031	Target Neighborhood Hits	939	Shared Neighborhood Hits	89
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 1106)	NC score	0.059805 (rank : 712)
Query Neighborhood Hits	1031	Target Neighborhood Hits	927	Shared Neighborhood Hits	90
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ENAH_HUMAN
θ value	θ > 10 (rank : 1107)	NC score	0.056704 (rank : 783)
Query Neighborhood Hits	1031	Target Neighborhood Hits	784	Shared Neighborhood Hits	177
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

ENAM_HUMAN
θ value	θ > 10 (rank : 1108)	NC score	0.052406 (rank : 859)
Query Neighborhood Hits	1031	Target Neighborhood Hits	227	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

ENL_HUMAN
θ value	θ > 10 (rank : 1109)	NC score	0.056511 (rank : 788)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	93
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

EP300_HUMAN
θ value	θ > 10 (rank : 1110)	NC score	0.108246 (rank : 393)
Query Neighborhood Hits	1031	Target Neighborhood Hits	821	Shared Neighborhood Hits	302
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ERBB2_HUMAN
θ value	θ > 10 (rank : 1111)	NC score	0.063694 (rank : 645)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1073	Shared Neighborhood Hits	155
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	θ > 10 (rank : 1112)	NC score	0.061098 (rank : 679)
Query Neighborhood Hits	1031	Target Neighborhood Hits	918	Shared Neighborhood Hits	98
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_HUMAN
θ value	θ > 10 (rank : 1113)	NC score	0.055479 (rank : 807)
Query Neighborhood Hits	1031	Target Neighborhood Hits	918	Shared Neighborhood Hits	89
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 1114)	NC score	0.055203 (rank : 816)
Query Neighborhood Hits	1031	Target Neighborhood Hits	898	Shared Neighborhood Hits	89
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 1115)	NC score	0.063005 (rank : 651)
Query Neighborhood Hits	1031	Target Neighborhood Hits	910	Shared Neighborhood Hits	92
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

FAK1_HUMAN
θ value	θ > 10 (rank : 1116)	NC score	0.061153 (rank : 678)
Query Neighborhood Hits	1031	Target Neighborhood Hits	850	Shared Neighborhood Hits	88
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 1117)	NC score	0.060836 (rank : 685)
Query Neighborhood Hits	1031	Target Neighborhood Hits	850	Shared Neighborhood Hits	84
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 1118)	NC score	0.062152 (rank : 664)
Query Neighborhood Hits	1031	Target Neighborhood Hits	847	Shared Neighborhood Hits	85
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 1119)	NC score	0.061708 (rank : 670)
Query Neighborhood Hits	1031	Target Neighborhood Hits	851	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FER_HUMAN
θ value	θ > 10 (rank : 1120)	NC score	0.061264 (rank : 676)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1278	Shared Neighborhood Hits	117
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FES_HUMAN
θ value	θ > 10 (rank : 1121)	NC score	0.057658 (rank : 767)
Query Neighborhood Hits	1031	Target Neighborhood Hits	978	Shared Neighborhood Hits	89
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
θ value	θ > 10 (rank : 1122)	NC score	0.058592 (rank : 740)
Query Neighborhood Hits	1031	Target Neighborhood Hits	980	Shared Neighborhood Hits	101
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FGR_HUMAN
θ value	θ > 10 (rank : 1123)	NC score	0.061980 (rank : 666)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1067	Shared Neighborhood Hits	127
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	θ > 10 (rank : 1124)	NC score	0.062427 (rank : 658)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1069	Shared Neighborhood Hits	128
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FRK_HUMAN
θ value	θ > 10 (rank : 1125)	NC score	0.060987 (rank : 682)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1058	Shared Neighborhood Hits	124
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FYN_HUMAN
θ value	θ > 10 (rank : 1126)	NC score	0.061933 (rank : 667)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1078	Shared Neighborhood Hits	129
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	θ > 10 (rank : 1127)	NC score	0.062673 (rank : 655)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1073	Shared Neighborhood Hits	129
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GRIN1_MOUSE
θ value	θ > 10 (rank : 1128)	NC score	0.074879 (rank : 542)
Query Neighborhood Hits	1031	Target Neighborhood Hits	337	Shared Neighborhood Hits	135
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GUC2C_HUMAN
θ value	θ > 10 (rank : 1129)	NC score	0.056312 (rank : 792)
Query Neighborhood Hits	1031	Target Neighborhood Hits	624	Shared Neighborhood Hits	64
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2E_MOUSE
θ value	θ > 10 (rank : 1130)	NC score	0.052089 (rank : 868)
Query Neighborhood Hits	1031	Target Neighborhood Hits	692	Shared Neighborhood Hits	71
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

GUC2F_HUMAN
θ value	θ > 10 (rank : 1131)	NC score	0.054925 (rank : 819)
Query Neighborhood Hits	1031	Target Neighborhood Hits	740	Shared Neighborhood Hits	73
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GUC2G_MOUSE
θ value	θ > 10 (rank : 1132)	NC score	0.059493 (rank : 719)
Query Neighborhood Hits	1031	Target Neighborhood Hits	644	Shared Neighborhood Hits	69
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

HCK_HUMAN
θ value	θ > 10 (rank : 1133)	NC score	0.060038 (rank : 709)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1035	Shared Neighborhood Hits	125
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 1134)	NC score	0.060699 (rank : 688)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1029	Shared Neighborhood Hits	125
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

IF35_MOUSE
θ value	θ > 10 (rank : 1135)	NC score	0.055738 (rank : 803)
Query Neighborhood Hits	1031	Target Neighborhood Hits	210	Shared Neighborhood Hits	111
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IGF1R_HUMAN
θ value	θ > 10 (rank : 1136)	NC score	0.057474 (rank : 770)
Query Neighborhood Hits	1031	Target Neighborhood Hits	977	Shared Neighborhood Hits	94
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 1137)	NC score	0.057884 (rank : 759)
Query Neighborhood Hits	1031	Target Neighborhood Hits	973	Shared Neighborhood Hits	95
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_HUMAN
θ value	θ > 10 (rank : 1138)	NC score	0.060667 (rank : 691)
Query Neighborhood Hits	1031	Target Neighborhood Hits	950	Shared Neighborhood Hits	100
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 1139)	NC score	0.060670 (rank : 690)
Query Neighborhood Hits	1031	Target Neighborhood Hits	961	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 1140)	NC score	0.060453 (rank : 696)
Query Neighborhood Hits	1031	Target Neighborhood Hits	963	Shared Neighborhood Hits	92
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 1141)	NC score	0.059706 (rank : 715)
Query Neighborhood Hits	1031	Target Neighborhood Hits	968	Shared Neighborhood Hits	91
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IRAK1_HUMAN
θ value	θ > 10 (rank : 1142)	NC score	0.061428 (rank : 674)
Query Neighborhood Hits	1031	Target Neighborhood Hits	820	Shared Neighborhood Hits	107
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	θ > 10 (rank : 1143)	NC score	0.056172 (rank : 794)
Query Neighborhood Hits	1031	Target Neighborhood Hits	784	Shared Neighborhood Hits	87
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

IRAK3_HUMAN
θ value	θ > 10 (rank : 1144)	NC score	0.066651 (rank : 611)
Query Neighborhood Hits	1031	Target Neighborhood Hits	644	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK3_MOUSE
θ value	θ > 10 (rank : 1145)	NC score	0.065218 (rank : 624)
Query Neighborhood Hits	1031	Target Neighborhood Hits	628	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

ITK_HUMAN
θ value	θ > 10 (rank : 1146)	NC score	0.059803 (rank : 713)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1016	Shared Neighborhood Hits	111
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 1147)	NC score	0.059317 (rank : 721)
Query Neighborhood Hits	1031	Target Neighborhood Hits	985	Shared Neighborhood Hits	106
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

IWS1_HUMAN
θ value	θ > 10 (rank : 1148)	NC score	0.068830 (rank : 589)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1241	Shared Neighborhood Hits	206
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JAG1_HUMAN
θ value	θ > 10 (rank : 1149)	NC score	0.050239 (rank : 910)
Query Neighborhood Hits	1031	Target Neighborhood Hits	514	Shared Neighborhood Hits	33
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 1150)	NC score	0.050182 (rank : 913)
Query Neighborhood Hits	1031	Target Neighborhood Hits	518	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 1151)	NC score	0.050494 (rank : 901)
Query Neighborhood Hits	1031	Target Neighborhood Hits	491	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 1152)	NC score	0.051812 (rank : 875)
Query Neighborhood Hits	1031	Target Neighborhood Hits	504	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

JAK1_HUMAN
θ value	θ > 10 (rank : 1153)	NC score	0.052424 (rank : 858)
Query Neighborhood Hits	1031	Target Neighborhood Hits	858	Shared Neighborhood Hits	80
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_MOUSE
θ value	θ > 10 (rank : 1154)	NC score	0.052268 (rank : 865)
Query Neighborhood Hits	1031	Target Neighborhood Hits	854	Shared Neighborhood Hits	81
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK2_HUMAN
θ value	θ > 10 (rank : 1155)	NC score	0.051124 (rank : 888)
Query Neighborhood Hits	1031	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK2_MOUSE
θ value	θ > 10 (rank : 1156)	NC score	0.050199 (rank : 911)
Query Neighborhood Hits	1031	Target Neighborhood Hits	839	Shared Neighborhood Hits	81
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK3_HUMAN
θ value	θ > 10 (rank : 1157)	NC score	0.050189 (rank : 912)
Query Neighborhood Hits	1031	Target Neighborhood Hits	827	Shared Neighborhood Hits	81
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

KI67_HUMAN
θ value	θ > 10 (rank : 1158)	NC score	0.067211 (rank : 604)
Query Neighborhood Hits	1031	Target Neighborhood Hits	581	Shared Neighborhood Hits	124
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KIT_HUMAN
θ value	θ > 10 (rank : 1159)	NC score	0.051590 (rank : 878)
Query Neighborhood Hits	1031	Target Neighborhood Hits	953	Shared Neighborhood Hits	80
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 1160)	NC score	0.051218 (rank : 886)
Query Neighborhood Hits	1031	Target Neighborhood Hits	949	Shared Neighborhood Hits	82
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KSR1_HUMAN
θ value	θ > 10 (rank : 1161)	NC score	0.052121 (rank : 866)
Query Neighborhood Hits	1031	Target Neighborhood Hits	867	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

KSR2_HUMAN
θ value	θ > 10 (rank : 1162)	NC score	0.051579 (rank : 879)
Query Neighborhood Hits	1031	Target Neighborhood Hits	920	Shared Neighborhood Hits	122
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

KSYK_HUMAN
θ value	θ > 10 (rank : 1163)	NC score	0.057983 (rank : 756)
Query Neighborhood Hits	1031	Target Neighborhood Hits	901	Shared Neighborhood Hits	88
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 1164)	NC score	0.058879 (rank : 730)
Query Neighborhood Hits	1031	Target Neighborhood Hits	944	Shared Neighborhood Hits	106
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAD1_MOUSE
θ value	θ > 10 (rank : 1165)	NC score	0.086912 (rank : 477)
Query Neighborhood Hits	1031	Target Neighborhood Hits	391	Shared Neighborhood Hits	116
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LCE1B_HUMAN
θ value	θ > 10 (rank : 1166)	NC score	0.054304 (rank : 831)
Query Neighborhood Hits	1031	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 1167)	NC score	0.053702 (rank : 841)
Query Neighborhood Hits	1031	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 1168)	NC score	0.054069 (rank : 833)
Query Neighborhood Hits	1031	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCK_HUMAN
θ value	θ > 10 (rank : 1169)	NC score	0.059412 (rank : 720)
Query Neighborhood Hits	1031	Target Neighborhood Hits	987	Shared Neighborhood Hits	111
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 1170)	NC score	0.059899 (rank : 711)
Query Neighborhood Hits	1031	Target Neighborhood Hits	981	Shared Neighborhood Hits	109
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LTBP2_HUMAN
θ value	θ > 10 (rank : 1171)	NC score	0.050325 (rank : 905)
Query Neighborhood Hits	1031	Target Neighborhood Hits	552	Shared Neighborhood Hits	71
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTK_HUMAN
θ value	θ > 10 (rank : 1172)	NC score	0.060530 (rank : 694)
Query Neighborhood Hits	1031	Target Neighborhood Hits	774	Shared Neighborhood Hits	81
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 1173)	NC score	0.060409 (rank : 699)
Query Neighborhood Hits	1031	Target Neighborhood Hits	770	Shared Neighborhood Hits	84
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LYN_HUMAN
θ value	θ > 10 (rank : 1174)	NC score	0.058663 (rank : 739)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1022	Shared Neighborhood Hits	119
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 1175)	NC score	0.058827 (rank : 732)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1023	Shared Neighborhood Hits	121
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M3K10_HUMAN
θ value	θ > 10 (rank : 1176)	NC score	0.064895 (rank : 629)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1071	Shared Neighborhood Hits	144
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

M3K12_HUMAN
θ value	θ > 10 (rank : 1177)	NC score	0.055791 (rank : 802)
Query Neighborhood Hits	1031	Target Neighborhood Hits	940	Shared Neighborhood Hits	118
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	θ > 10 (rank : 1178)	NC score	0.055214 (rank : 815)
Query Neighborhood Hits	1031	Target Neighborhood Hits	957	Shared Neighborhood Hits	109
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K13_HUMAN
θ value	θ > 10 (rank : 1179)	NC score	0.053122 (rank : 851)
Query Neighborhood Hits	1031	Target Neighborhood Hits	911	Shared Neighborhood Hits	95
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M3K7_HUMAN
θ value	θ > 10 (rank : 1180)	NC score	0.058118 (rank : 752)
Query Neighborhood Hits	1031	Target Neighborhood Hits	892	Shared Neighborhood Hits	83
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_MOUSE
θ value	θ > 10 (rank : 1181)	NC score	0.058176 (rank : 750)
Query Neighborhood Hits	1031	Target Neighborhood Hits	892	Shared Neighborhood Hits	84
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K9_HUMAN
θ value	θ > 10 (rank : 1182)	NC score	0.063143 (rank : 649)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1123	Shared Neighborhood Hits	170
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M3KL4_HUMAN
θ value	θ > 10 (rank : 1183)	NC score	0.062787 (rank : 653)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1087	Shared Neighborhood Hits	145
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MADCA_HUMAN
θ value	θ > 10 (rank : 1184)	NC score	0.073018 (rank : 558)
Query Neighborhood Hits	1031	Target Neighborhood Hits	221	Shared Neighborhood Hits	104
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAP1B_MOUSE
θ value	θ > 10 (rank : 1185)	NC score	0.055367 (rank : 812)
Query Neighborhood Hits	1031	Target Neighborhood Hits	977	Shared Neighborhood Hits	172
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAP4_HUMAN
θ value	θ > 10 (rank : 1186)	NC score	0.072160 (rank : 565)
Query Neighborhood Hits	1031	Target Neighborhood Hits	428	Shared Neighborhood Hits	148
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP4_MOUSE
θ value	θ > 10 (rank : 1187)	NC score	0.066757 (rank : 609)
Query Neighborhood Hits	1031	Target Neighborhood Hits	409	Shared Neighborhood Hits	127
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 1188)	NC score	0.083156 (rank : 499)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	78
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 1189)	NC score	0.075934 (rank : 532)
Query Neighborhood Hits	1031	Target Neighborhood Hits	227	Shared Neighborhood Hits	78
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MATK_HUMAN
θ value	θ > 10 (rank : 1190)	NC score	0.058073 (rank : 754)
Query Neighborhood Hits	1031	Target Neighborhood Hits	954	Shared Neighborhood Hits	98
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 1191)	NC score	0.057661 (rank : 766)
Query Neighborhood Hits	1031	Target Neighborhood Hits	952	Shared Neighborhood Hits	97
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MEGF9_HUMAN
θ value	θ > 10 (rank : 1192)	NC score	0.057856 (rank : 761)
Query Neighborhood Hits	1031	Target Neighborhood Hits	557	Shared Neighborhood Hits	142
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MERTK_HUMAN
θ value	θ > 10 (rank : 1193)	NC score	0.059135 (rank : 724)
Query Neighborhood Hits	1031	Target Neighborhood Hits	988	Shared Neighborhood Hits	87
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	θ > 10 (rank : 1194)	NC score	0.058950 (rank : 728)
Query Neighborhood Hits	1031	Target Neighborhood Hits	974	Shared Neighborhood Hits	84
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MET_HUMAN
θ value	θ > 10 (rank : 1195)	NC score	0.059001 (rank : 727)
Query Neighborhood Hits	1031	Target Neighborhood Hits	831	Shared Neighborhood Hits	80
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 1196)	NC score	0.058783 (rank : 733)
Query Neighborhood Hits	1031	Target Neighborhood Hits	844	Shared Neighborhood Hits	83
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MILK1_HUMAN
θ value	θ > 10 (rank : 1197)	NC score	0.063745 (rank : 644)
Query Neighborhood Hits	1031	Target Neighborhood Hits	427	Shared Neighborhood Hits	159
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MLKL_HUMAN
θ value	θ > 10 (rank : 1198)	NC score	0.068558 (rank : 591)
Query Neighborhood Hits	1031	Target Neighborhood Hits	600	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 1199)	NC score	0.061512 (rank : 671)
Query Neighborhood Hits	1031	Target Neighborhood Hits	707	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLTK_HUMAN
θ value	θ > 10 (rank : 1200)	NC score	0.056953 (rank : 777)
Query Neighborhood Hits	1031	Target Neighborhood Hits	911	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
θ value	θ > 10 (rank : 1201)	NC score	0.056532 (rank : 787)
Query Neighborhood Hits	1031	Target Neighborhood Hits	874	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MNT_MOUSE
θ value	θ > 10 (rank : 1202)	NC score	0.064958 (rank : 627)
Query Neighborhood Hits	1031	Target Neighborhood Hits	432	Shared Neighborhood Hits	155
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MOS_HUMAN
θ value	θ > 10 (rank : 1203)	NC score	0.052350 (rank : 862)
Query Neighborhood Hits	1031	Target Neighborhood Hits	829	Shared Neighborhood Hits	80
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MTSS1_HUMAN
θ value	θ > 10 (rank : 1204)	NC score	0.055562 (rank : 806)
Query Neighborhood Hits	1031	Target Neighborhood Hits	504	Shared Neighborhood Hits	176
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MUC13_MOUSE
θ value	θ > 10 (rank : 1205)	NC score	0.083581 (rank : 497)
Query Neighborhood Hits	1031	Target Neighborhood Hits	447	Shared Neighborhood Hits	110
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	θ > 10 (rank : 1206)	NC score	0.081020 (rank : 509)
Query Neighborhood Hits	1031	Target Neighborhood Hits	388	Shared Neighborhood Hits	96
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUCDL_HUMAN
θ value	θ > 10 (rank : 1207)	NC score	0.101858 (rank : 425)
Query Neighborhood Hits	1031	Target Neighborhood Hits	777	Shared Neighborhood Hits	282
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUSK_HUMAN
θ value	θ > 10 (rank : 1208)	NC score	0.053143 (rank : 850)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1074	Shared Neighborhood Hits	79
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 1209)	NC score	0.052515 (rank : 856)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1057	Shared Neighborhood Hits	79
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

NFH_HUMAN
θ value	θ > 10 (rank : 1210)	NC score	0.052270 (rank : 864)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1242	Shared Neighborhood Hits	202
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOLC1_HUMAN
θ value	θ > 10 (rank : 1211)	NC score	0.086490 (rank : 479)
Query Neighborhood Hits	1031	Target Neighborhood Hits	452	Shared Neighborhood Hits	117
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NSD1_MOUSE
θ value	θ > 10 (rank : 1212)	NC score	0.054037 (rank : 834)
Query Neighborhood Hits	1031	Target Neighborhood Hits	472	Shared Neighborhood Hits	124
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NTRK1_HUMAN
θ value	θ > 10 (rank : 1213)	NC score	0.057872 (rank : 760)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1023	Shared Neighborhood Hits	82
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 1214)	NC score	0.054668 (rank : 826)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1081	Shared Neighborhood Hits	84
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 1215)	NC score	0.054535 (rank : 828)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1088	Shared Neighborhood Hits	84
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 1216)	NC score	0.055146 (rank : 818)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1115	Shared Neighborhood Hits	86
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

OGFR_MOUSE
θ value	θ > 10 (rank : 1217)	NC score	0.082780 (rank : 503)
Query Neighborhood Hits	1031	Target Neighborhood Hits	584	Shared Neighborhood Hits	161
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PCQAP_HUMAN
θ value	θ > 10 (rank : 1218)	NC score	0.085838 (rank : 485)
Query Neighborhood Hits	1031	Target Neighborhood Hits	549	Shared Neighborhood Hits	167
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 1219)	NC score	0.064833 (rank : 630)
Query Neighborhood Hits	1031	Target Neighborhood Hits	506	Shared Neighborhood Hits	153
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDC6I_HUMAN
θ value	θ > 10 (rank : 1220)	NC score	0.055228 (rank : 814)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PHC2_HUMAN
θ value	θ > 10 (rank : 1221)	NC score	0.061489 (rank : 673)
Query Neighborhood Hits	1031	Target Neighborhood Hits	388	Shared Neighborhood Hits	166
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PO121_HUMAN
θ value	θ > 10 (rank : 1222)	NC score	0.072966 (rank : 559)
Query Neighborhood Hits	1031	Target Neighborhood Hits	344	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 1223)	NC score	0.070847 (rank : 578)
Query Neighborhood Hits	1031	Target Neighborhood Hits	345	Shared Neighborhood Hits	123
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PTK6_HUMAN
θ value	θ > 10 (rank : 1224)	NC score	0.058592 (rank : 741)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1020	Shared Neighborhood Hits	121
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 1225)	NC score	0.058472 (rank : 744)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1026	Shared Neighborhood Hits	120
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

RAF1_HUMAN
θ value	θ > 10 (rank : 1226)	NC score	0.056695 (rank : 784)
Query Neighborhood Hits	1031	Target Neighborhood Hits	886	Shared Neighborhood Hits	90
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	θ > 10 (rank : 1227)	NC score	0.056594 (rank : 785)
Query Neighborhood Hits	1031	Target Neighborhood Hits	886	Shared Neighborhood Hits	90
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RELB_HUMAN
θ value	θ > 10 (rank : 1228)	NC score	0.050685 (rank : 898)
Query Neighborhood Hits	1031	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

RELB_MOUSE
θ value	θ > 10 (rank : 1229)	NC score	0.050808 (rank : 894)
Query Neighborhood Hits	1031	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

REL_HUMAN
θ value	θ > 10 (rank : 1230)	NC score	0.052061 (rank : 870)
Query Neighborhood Hits	1031	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

REL_MOUSE
θ value	θ > 10 (rank : 1231)	NC score	0.056103 (rank : 796)
Query Neighborhood Hits	1031	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

RERE_HUMAN
θ value	θ > 10 (rank : 1232)	NC score	0.113468 (rank : 368)
Query Neighborhood Hits	1031	Target Neighborhood Hits	779	Shared Neighborhood Hits	276
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 1233)	NC score	0.114998 (rank : 361)
Query Neighborhood Hits	1031	Target Neighborhood Hits	785	Shared Neighborhood Hits	276
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RET_HUMAN
θ value	θ > 10 (rank : 1234)	NC score	0.055934 (rank : 801)
Query Neighborhood Hits	1031	Target Neighborhood Hits	873	Shared Neighborhood Hits	80
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 1235)	NC score	0.056411 (rank : 790)
Query Neighborhood Hits	1031	Target Neighborhood Hits	884	Shared Neighborhood Hits	82
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIPK1_HUMAN
θ value	θ > 10 (rank : 1236)	NC score	0.053418 (rank : 845)
Query Neighborhood Hits	1031	Target Neighborhood Hits	891	Shared Neighborhood Hits	89
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_MOUSE
θ value	θ > 10 (rank : 1237)	NC score	0.051333 (rank : 884)
Query Neighborhood Hits	1031	Target Neighborhood Hits	874	Shared Neighborhood Hits	89
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK2_HUMAN
θ value	θ > 10 (rank : 1238)	NC score	0.071305 (rank : 575)
Query Neighborhood Hits	1031	Target Neighborhood Hits	774	Shared Neighborhood Hits	77
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	θ > 10 (rank : 1239)	NC score	0.065751 (rank : 620)
Query Neighborhood Hits	1031	Target Neighborhood Hits	776	Shared Neighborhood Hits	77
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK3_HUMAN
θ value	θ > 10 (rank : 1240)	NC score	0.060925 (rank : 683)
Query Neighborhood Hits	1031	Target Neighborhood Hits	828	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

RIPK3_MOUSE
θ value	θ > 10 (rank : 1241)	NC score	0.060284 (rank : 703)
Query Neighborhood Hits	1031	Target Neighborhood Hits	867	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

RON_HUMAN
θ value	θ > 10 (rank : 1242)	NC score	0.056819 (rank : 781)
Query Neighborhood Hits	1031	Target Neighborhood Hits	842	Shared Neighborhood Hits	85
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 1243)	NC score	0.056857 (rank : 778)
Query Neighborhood Hits	1031	Target Neighborhood Hits	836	Shared Neighborhood Hits	82
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 1244)	NC score	0.059774 (rank : 714)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1018	Shared Neighborhood Hits	86
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 1245)	NC score	0.059640 (rank : 718)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1025	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 1246)	NC score	0.059221 (rank : 723)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1014	Shared Neighborhood Hits	88
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 1247)	NC score	0.060111 (rank : 707)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1000	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

ROS_HUMAN
θ value	θ > 10 (rank : 1248)	NC score	0.058397 (rank : 746)
Query Neighborhood Hits	1031	Target Neighborhood Hits	907	Shared Neighborhood Hits	84
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

RYK_HUMAN
θ value	θ > 10 (rank : 1249)	NC score	0.058178 (rank : 749)
Query Neighborhood Hits	1031	Target Neighborhood Hits	701	Shared Neighborhood Hits	70
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 1250)	NC score	0.057623 (rank : 768)
Query Neighborhood Hits	1031	Target Neighborhood Hits	715	Shared Neighborhood Hits	71
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

S23IP_HUMAN
θ value	θ > 10 (rank : 1251)	NC score	0.056118 (rank : 795)
Query Neighborhood Hits	1031	Target Neighborhood Hits	134	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

SAM14_HUMAN
θ value	θ > 10 (rank : 1252)	NC score	0.056821 (rank : 780)
Query Neighborhood Hits	1031	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SAM14_MOUSE
θ value	θ > 10 (rank : 1253)	NC score	0.060109 (rank : 708)
Query Neighborhood Hits	1031	Target Neighborhood Hits	91	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SC24A_MOUSE
θ value	θ > 10 (rank : 1254)	NC score	0.061929 (rank : 668)
Query Neighborhood Hits	1031	Target Neighborhood Hits	394	Shared Neighborhood Hits	182
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SELPL_MOUSE
θ value	θ > 10 (rank : 1255)	NC score	0.084192 (rank : 495)
Query Neighborhood Hits	1031	Target Neighborhood Hits	588	Shared Neighborhood Hits	212
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SELV_HUMAN
θ value	θ > 10 (rank : 1256)	NC score	0.072097 (rank : 566)
Query Neighborhood Hits	1031	Target Neighborhood Hits	118	Shared Neighborhood Hits	70
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SET1A_HUMAN
θ value	θ > 10 (rank : 1257)	NC score	0.107735 (rank : 397)
Query Neighborhood Hits	1031	Target Neighborhood Hits	690	Shared Neighborhood Hits	209
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD2_HUMAN
θ value	θ > 10 (rank : 1258)	NC score	0.055374 (rank : 811)
Query Neighborhood Hits	1031	Target Neighborhood Hits	412	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SF01_HUMAN
θ value	θ > 10 (rank : 1259)	NC score	0.065711 (rank : 622)
Query Neighborhood Hits	1031	Target Neighborhood Hits	287	Shared Neighborhood Hits	137
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 1260)	NC score	0.055461 (rank : 808)
Query Neighborhood Hits	1031	Target Neighborhood Hits	240	Shared Neighborhood Hits	108
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SGIP1_HUMAN
θ value	θ > 10 (rank : 1261)	NC score	0.066592 (rank : 612)
Query Neighborhood Hits	1031	Target Neighborhood Hits	198	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SMAP1_HUMAN
θ value	θ > 10 (rank : 1262)	NC score	0.062772 (rank : 654)
Query Neighborhood Hits	1031	Target Neighborhood Hits	98	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMOO_HUMAN
θ value	θ > 10 (rank : 1263)	NC score	0.053373 (rank : 846)
Query Neighborhood Hits	1031	Target Neighborhood Hits	391	Shared Neighborhood Hits	143
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SMP1L_HUMAN
θ value	θ > 10 (rank : 1264)	NC score	0.060770 (rank : 686)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 1265)	NC score	0.058720 (rank : 738)
Query Neighborhood Hits	1031	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SNPC4_HUMAN
θ value	θ > 10 (rank : 1266)	NC score	0.085092 (rank : 489)
Query Neighborhood Hits	1031	Target Neighborhood Hits	589	Shared Neighborhood Hits	241
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SRC_HUMAN
θ value	θ > 10 (rank : 1267)	NC score	0.061089 (rank : 680)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1058	Shared Neighborhood Hits	131
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRC_MOUSE
θ value	θ > 10 (rank : 1268)	NC score	0.060128 (rank : 706)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1033	Shared Neighborhood Hits	125
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRMS_HUMAN
θ value	θ > 10 (rank : 1269)	NC score	0.056220 (rank : 793)
Query Neighborhood Hits	1031	Target Neighborhood Hits	946	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 1270)	NC score	0.055948 (rank : 800)
Query Neighborhood Hits	1031	Target Neighborhood Hits	964	Shared Neighborhood Hits	101
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

T22D2_HUMAN
θ value	θ > 10 (rank : 1271)	NC score	0.072736 (rank : 562)
Query Neighborhood Hits	1031	Target Neighborhood Hits	250	Shared Neighborhood Hits	114
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TACC2_HUMAN
θ value	θ > 10 (rank : 1272)	NC score	0.051938 (rank : 873)
Query Neighborhood Hits	1031	Target Neighborhood Hits	856	Shared Neighborhood Hits	159
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 1273)	NC score	0.053312 (rank : 847)
Query Neighborhood Hits	1031	Target Neighborhood Hits	774	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TARA_HUMAN
θ value	θ > 10 (rank : 1274)	NC score	0.094289 (rank : 445)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1626	Shared Neighborhood Hits	349
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_HUMAN
θ value	θ > 10 (rank : 1275)	NC score	0.077297 (rank : 527)
Query Neighborhood Hits	1031	Target Neighborhood Hits	448	Shared Neighborhood Hits	186
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCGAP_HUMAN
θ value	θ > 10 (rank : 1276)	NC score	0.095837 (rank : 440)
Query Neighborhood Hits	1031	Target Neighborhood Hits	872	Shared Neighborhood Hits	327
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCOF_HUMAN
θ value	θ > 10 (rank : 1277)	NC score	0.073204 (rank : 556)
Query Neighborhood Hits	1031	Target Neighborhood Hits	543	Shared Neighborhood Hits	137
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 1278)	NC score	0.084797 (rank : 493)
Query Neighborhood Hits	1031	Target Neighborhood Hits	471	Shared Neighborhood Hits	145
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TEC_HUMAN
θ value	θ > 10 (rank : 1279)	NC score	0.060428 (rank : 698)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1006	Shared Neighborhood Hits	113
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 1280)	NC score	0.059658 (rank : 716)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1006	Shared Neighborhood Hits	113
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TENX_HUMAN
θ value	θ > 10 (rank : 1281)	NC score	0.053754 (rank : 840)
Query Neighborhood Hits	1031	Target Neighborhood Hits	789	Shared Neighborhood Hits	113
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TESK2_HUMAN
θ value	θ > 10 (rank : 1282)	NC score	0.052120 (rank : 867)
Query Neighborhood Hits	1031	Target Neighborhood Hits	851	Shared Neighborhood Hits	88
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TF65_HUMAN
θ value	θ > 10 (rank : 1283)	NC score	0.066169 (rank : 617)
Query Neighborhood Hits	1031	Target Neighborhood Hits	115	Shared Neighborhood Hits	54
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TF65_MOUSE
θ value	θ > 10 (rank : 1284)	NC score	0.054232 (rank : 832)
Query Neighborhood Hits	1031	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TGON2_HUMAN
θ value	θ > 10 (rank : 1285)	NC score	0.086060 (rank : 482)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1037	Shared Neighborhood Hits	228
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIE1_HUMAN
θ value	θ > 10 (rank : 1286)	NC score	0.068426 (rank : 594)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1241	Shared Neighborhood Hits	108
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 1287)	NC score	0.068485 (rank : 593)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1266	Shared Neighborhood Hits	107
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 1288)	NC score	0.067378 (rank : 603)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1192	Shared Neighborhood Hits	101
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 1289)	NC score	0.067629 (rank : 600)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1204	Shared Neighborhood Hits	102
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TM108_MOUSE
θ value	θ > 10 (rank : 1290)	NC score	0.078967 (rank : 517)
Query Neighborhood Hits	1031	Target Neighborhood Hits	336	Shared Neighborhood Hits	145
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMAP1_HUMAN
θ value	θ > 10 (rank : 1291)	NC score	0.055255 (rank : 813)
Query Neighborhood Hits	1031	Target Neighborhood Hits	140	Shared Neighborhood Hits	58
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TNK1_HUMAN
θ value	θ > 10 (rank : 1292)	NC score	0.064492 (rank : 639)
Query Neighborhood Hits	1031	Target Neighborhood Hits	815	Shared Neighborhood Hits	93
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 1293)	NC score	0.060989 (rank : 681)
Query Neighborhood Hits	1031	Target Neighborhood Hits	806	Shared Neighborhood Hits	86
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TOPK_HUMAN
θ value	θ > 10 (rank : 1294)	NC score	0.051428 (rank : 881)
Query Neighborhood Hits	1031	Target Neighborhood Hits	605	Shared Neighborhood Hits	65
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

TRDN_HUMAN
θ value	θ > 10 (rank : 1295)	NC score	0.062332 (rank : 660)
Query Neighborhood Hits	1031	Target Neighborhood Hits	542	Shared Neighborhood Hits	77
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRPC3_MOUSE
θ value	θ > 10 (rank : 1296)	NC score	0.075923 (rank : 533)
Query Neighborhood Hits	1031	Target Neighborhood Hits	131	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_HUMAN
θ value	θ > 10 (rank : 1297)	NC score	0.102094 (rank : 423)
Query Neighborhood Hits	1031	Target Neighborhood Hits	171	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC6_MOUSE
θ value	θ > 10 (rank : 1298)	NC score	0.075196 (rank : 537)
Query Neighborhood Hits	1031	Target Neighborhood Hits	171	Shared Neighborhood Hits	97
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_HUMAN
θ value	θ > 10 (rank : 1299)	NC score	0.071500 (rank : 572)
Query Neighborhood Hits	1031	Target Neighborhood Hits	123	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	θ > 10 (rank : 1300)	NC score	0.070348 (rank : 581)
Query Neighborhood Hits	1031	Target Neighborhood Hits	114	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPV3_MOUSE
θ value	θ > 10 (rank : 1301)	NC score	0.222919 (rank : 289)
Query Neighborhood Hits	1031	Target Neighborhood Hits	188	Shared Neighborhood Hits	132
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	θ > 10 (rank : 1302)	NC score	0.116785 (rank : 358)
Query Neighborhood Hits	1031	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 1303)	NC score	0.107375 (rank : 403)
Query Neighborhood Hits	1031	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TXK_HUMAN
θ value	θ > 10 (rank : 1304)	NC score	0.062558 (rank : 657)
Query Neighborhood Hits	1031	Target Neighborhood Hits	971	Shared Neighborhood Hits	112
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1305)	NC score	0.062064 (rank : 665)
Query Neighborhood Hits	1031	Target Neighborhood Hits	980	Shared Neighborhood Hits	114
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TYK2_MOUSE
θ value	θ > 10 (rank : 1306)	NC score	0.050258 (rank : 907)
Query Neighborhood Hits	1031	Target Neighborhood Hits	850	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYRO3_HUMAN
θ value	θ > 10 (rank : 1307)	NC score	0.057532 (rank : 769)
Query Neighborhood Hits	1031	Target Neighborhood Hits	995	Shared Neighborhood Hits	82
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	θ > 10 (rank : 1308)	NC score	0.057937 (rank : 757)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1007	Shared Neighborhood Hits	84
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

UFO_HUMAN
θ value	θ > 10 (rank : 1309)	NC score	0.058729 (rank : 737)
Query Neighborhood Hits	1031	Target Neighborhood Hits	981	Shared Neighborhood Hits	99
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 1310)	NC score	0.058759 (rank : 735)
Query Neighborhood Hits	1031	Target Neighborhood Hits	988	Shared Neighborhood Hits	92
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

WASF4_HUMAN
θ value	θ > 10 (rank : 1311)	NC score	0.086169 (rank : 481)
Query Neighborhood Hits	1031	Target Neighborhood Hits	282	Shared Neighborhood Hits	152
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WNK1_HUMAN
θ value	θ > 10 (rank : 1312)	NC score	0.054804 (rank : 823)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1158	Shared Neighborhood Hits	209
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

YES_HUMAN
θ value	θ > 10 (rank : 1313)	NC score	0.062896 (rank : 652)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1059	Shared Neighborhood Hits	133
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 1314)	NC score	0.062619 (rank : 656)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1052	Shared Neighborhood Hits	128
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ZAN_MOUSE
θ value	θ > 10 (rank : 1315)	NC score	0.058094 (rank : 753)
Query Neighborhood Hits	1031	Target Neighborhood Hits	808	Shared Neighborhood Hits	93
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZAP70_HUMAN
θ value	θ > 10 (rank : 1316)	NC score	0.061498 (rank : 672)
Query Neighborhood Hits	1031	Target Neighborhood Hits	893	Shared Neighborhood Hits	91
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 1317)	NC score	0.060490 (rank : 695)
Query Neighborhood Hits	1031	Target Neighborhood Hits	905	Shared Neighborhood Hits	91
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZIM10_HUMAN
θ value	θ > 10 (rank : 1318)	NC score	0.060557 (rank : 693)
Query Neighborhood Hits	1031	Target Neighborhood Hits	577	Shared Neighborhood Hits	228
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN207_HUMAN
θ value	θ > 10 (rank : 1319)	NC score	0.088145 (rank : 469)
Query Neighborhood Hits	1031	Target Neighborhood Hits	326	Shared Neighborhood Hits	104
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

CSKI1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1031	Shared Neighborhood Hits	1031
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_HUMAN
NC score	0.976254 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	1031	Target Neighborhood Hits	997	Shared Neighborhood Hits	714
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
NC score	0.942212 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	1031	Target Neighborhood Hits	747	Shared Neighborhood Hits	520
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
NC score	0.941009 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	1031	Target Neighborhood Hits	812	Shared Neighborhood Hits	529
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKS1_HUMAN
NC score	0.879795 (rank : 5)	θ value	2.58187e-47 (rank : 5)
Query Neighborhood Hits	1031	Target Neighborhood Hits	438	Shared Neighborhood Hits	343
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
NC score	0.872490 (rank : 6)	θ value	1.41672e-45 (rank : 6)
Query Neighborhood Hits	1031	Target Neighborhood Hits	453	Shared Neighborhood Hits	351
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR29_HUMAN
NC score	0.867573 (rank : 7)	θ value	7.82807e-20 (rank : 43)
Query Neighborhood Hits	1031	Target Neighborhood Hits	294	Shared Neighborhood Hits	284
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

PSD10_HUMAN
NC score	0.866894 (rank : 8)	θ value	3.88503e-19 (rank : 49)
Query Neighborhood Hits	1031	Target Neighborhood Hits	301	Shared Neighborhood Hits	291
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.865168 (rank : 9)	θ value	1.13037e-18 (rank : 51)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR6_HUMAN
NC score	0.863962 (rank : 10)	θ value	7.56453e-23 (rank : 29)
Query Neighborhood Hits	1031	Target Neighborhood Hits	439	Shared Neighborhood Hits	314
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR16_HUMAN
NC score	0.860134 (rank : 11)	θ value	1.13037e-18 (rank : 50)
Query Neighborhood Hits	1031	Target Neighborhood Hits	286	Shared Neighborhood Hits	280
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR50_HUMAN
NC score	0.858920 (rank : 12)	θ value	1.05554e-24 (rank : 18)
Query Neighborhood Hits	1031	Target Neighborhood Hits	361	Shared Neighborhood Hits	300
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

TNKS1_HUMAN
NC score	0.856055 (rank : 13)	θ value	4.01107e-24 (rank : 21)
Query Neighborhood Hits	1031	Target Neighborhood Hits	477	Shared Neighborhood Hits	372
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ASB7_MOUSE
NC score	0.853677 (rank : 14)	θ value	1.33526e-19 (rank : 44)
Query Neighborhood Hits	1031	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.853669 (rank : 15)	θ value	1.74391e-19 (rank : 45)
Query Neighborhood Hits	1031	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR42_HUMAN
NC score	0.853158 (rank : 16)	θ value	1.09232e-21 (rank : 32)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR42_MOUSE
NC score	0.849690 (rank : 17)	θ value	1.5773e-20 (rank : 41)
Query Neighborhood Hits	1031	Target Neighborhood Hits	334	Shared Neighborhood Hits	282
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

INVS_HUMAN
NC score	0.849085 (rank : 18)	θ value	2.35151e-24 (rank : 20)
Query Neighborhood Hits	1031	Target Neighborhood Hits	455	Shared Neighborhood Hits	327
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ASB3_MOUSE
NC score	0.849085 (rank : 19)	θ value	1.42661e-21 (rank : 34)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	290
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_HUMAN
NC score	0.849032 (rank : 20)	θ value	1.2077e-20 (rank : 38)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB10_MOUSE
NC score	0.848872 (rank : 21)	θ value	1.5773e-20 (rank : 42)
Query Neighborhood Hits	1031	Target Neighborhood Hits	301	Shared Neighborhood Hits	285
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB10_HUMAN
NC score	0.848849 (rank : 22)	θ value	1.09232e-21 (rank : 33)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

TNKS2_HUMAN
NC score	0.847226 (rank : 23)	θ value	1.24688e-25 (rank : 14)
Query Neighborhood Hits	1031	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

INVS_MOUSE
NC score	0.846937 (rank : 24)	θ value	8.93572e-24 (rank : 22)
Query Neighborhood Hits	1031	Target Neighborhood Hits	609	Shared Neighborhood Hits	388
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR44_HUMAN
NC score	0.846727 (rank : 25)	θ value	1.05554e-24 (rank : 17)
Query Neighborhood Hits	1031	Target Neighborhood Hits	318	Shared Neighborhood Hits	298
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR28_MOUSE
NC score	0.846678 (rank : 26)	θ value	1.47289e-26 (rank : 12)
Query Neighborhood Hits	1031	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

FANK1_HUMAN
NC score	0.845460 (rank : 27)	θ value	3.07829e-16 (rank : 63)
Query Neighborhood Hits	1031	Target Neighborhood Hits	326	Shared Neighborhood Hits	293
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANR28_HUMAN
NC score	0.845427 (rank : 28)	θ value	1.92365e-26 (rank : 13)
Query Neighborhood Hits	1031	Target Neighborhood Hits	314	Shared Neighborhood Hits	297
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

FANK1_MOUSE
NC score	0.843974 (rank : 29)	θ value	1.99529e-15 (rank : 73)
Query Neighborhood Hits	1031	Target Neighborhood Hits	325	Shared Neighborhood Hits	292
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANK1_HUMAN
NC score	0.840131 (rank : 30)	θ value	4.57862e-28 (rank : 9)
Query Neighborhood Hits	1031	Target Neighborhood Hits	416	Shared Neighborhood Hits	309
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.839473 (rank : 31)	θ value	7.06379e-29 (rank : 7)
Query Neighborhood Hits	1031	Target Neighborhood Hits	430	Shared Neighborhood Hits	310
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANR52_MOUSE
NC score	0.838746 (rank : 32)	θ value	4.43474e-23 (rank : 27)
Query Neighborhood Hits	1031	Target Neighborhood Hits	318	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.838374 (rank : 33)	θ value	3.39556e-23 (rank : 26)
Query Neighborhood Hits	1031	Target Neighborhood Hits	322	Shared Neighborhood Hits	297
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR39_HUMAN
NC score	0.836612 (rank : 34)	θ value	7.09661e-13 (rank : 105)
Query Neighborhood Hits	1031	Target Neighborhood Hits	285	Shared Neighborhood Hits	280
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_MOUSE
NC score	0.835301 (rank : 35)	θ value	4.59992e-12 (rank : 120)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANK3_HUMAN
NC score	0.834807 (rank : 36)	θ value	8.63488e-27 (rank : 11)
Query Neighborhood Hits	1031	Target Neighborhood Hits	853	Shared Neighborhood Hits	381
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANKR2_MOUSE
NC score	0.834277 (rank : 37)	θ value	4.44505e-15 (rank : 74)
Query Neighborhood Hits	1031	Target Neighborhood Hits	312	Shared Neighborhood Hits	287
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR2_HUMAN
NC score	0.831125 (rank : 38)	θ value	1.86753e-13 (rank : 98)
Query Neighborhood Hits	1031	Target Neighborhood Hits	321	Shared Neighborhood Hits	290
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ASB13_MOUSE
NC score	0.830731 (rank : 39)	θ value	3.07829e-16 (rank : 62)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_HUMAN
NC score	0.830415 (rank : 40)	θ value	2.35696e-16 (rank : 61)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANR23_MOUSE
NC score	0.830113 (rank : 41)	θ value	2.98157e-11 (rank : 131)
Query Neighborhood Hits	1031	Target Neighborhood Hits	296	Shared Neighborhood Hits	285
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB2_HUMAN
NC score	0.829959 (rank : 42)	θ value	1.68911e-14 (rank : 79)
Query Neighborhood Hits	1031	Target Neighborhood Hits	309	Shared Neighborhood Hits	287
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

BCL3_HUMAN
NC score	0.827281 (rank : 43)	θ value	2.88119e-14 (rank : 86)
Query Neighborhood Hits	1031	Target Neighborhood Hits	324	Shared Neighborhood Hits	302
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ANR23_HUMAN
NC score	0.825972 (rank : 44)	θ value	1.47974e-10 (rank : 142)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	285
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

MYPT1_MOUSE
NC score	0.825528 (rank : 45)	θ value	1.99067e-23 (rank : 24)
Query Neighborhood Hits	1031	Target Neighborhood Hits	539	Shared Neighborhood Hits	313
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

BCL3_MOUSE
NC score	0.825139 (rank : 46)	θ value	8.38298e-14 (rank : 94)
Query Neighborhood Hits	1031	Target Neighborhood Hits	388	Shared Neighborhood Hits	322
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANKS6_MOUSE
NC score	0.825115 (rank : 47)	θ value	6.85773e-16 (rank : 68)
Query Neighborhood Hits	1031	Target Neighborhood Hits	435	Shared Neighborhood Hits	345
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

PA2G6_MOUSE
NC score	0.824971 (rank : 48)	θ value	1.74391e-19 (rank : 47)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

CDN2C_HUMAN
NC score	0.824765 (rank : 49)	θ value	3.76295e-14 (rank : 89)
Query Neighborhood Hits	1031	Target Neighborhood Hits	262	Shared Neighborhood Hits	260
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

TRPA1_MOUSE
NC score	0.824746 (rank : 50)	θ value	5.60996e-18 (rank : 54)
Query Neighborhood Hits	1031	Target Neighborhood Hits	343	Shared Neighborhood Hits	290
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPA1_HUMAN
NC score	0.824672 (rank : 51)	θ value	2.97466e-19 (rank : 48)
Query Neighborhood Hits	1031	Target Neighborhood Hits	339	Shared Neighborhood Hits	291
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ASB2_MOUSE
NC score	0.824576 (rank : 52)	θ value	5.25075e-16 (rank : 66)
Query Neighborhood Hits	1031	Target Neighborhood Hits	321	Shared Neighborhood Hits	286
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANKS6_HUMAN
NC score	0.824384 (rank : 53)	θ value	4.02038e-16 (rank : 64)
Query Neighborhood Hits	1031	Target Neighborhood Hits	411	Shared Neighborhood Hits	329
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

CDN2C_MOUSE
NC score	0.824142 (rank : 54)	θ value	1.86753e-13 (rank : 100)
Query Neighborhood Hits	1031	Target Neighborhood Hits	270	Shared Neighborhood Hits	266
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANKR1_HUMAN
NC score	0.822687 (rank : 55)	θ value	2.98157e-11 (rank : 130)
Query Neighborhood Hits	1031	Target Neighborhood Hits	308	Shared Neighborhood Hits	280
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
NC score	0.820355 (rank : 56)	θ value	3.89403e-11 (rank : 136)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	283
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

GABP2_MOUSE
NC score	0.816759 (rank : 57)	θ value	4.30538e-10 (rank : 148)
Query Neighborhood Hits	1031	Target Neighborhood Hits	429	Shared Neighborhood Hits	290
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

MIB1_HUMAN
NC score	0.815872 (rank : 58)	θ value	9.87957e-23 (rank : 30)
Query Neighborhood Hits	1031	Target Neighborhood Hits	470	Shared Neighborhood Hits	299
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.815560 (rank : 59)	θ value	9.87957e-23 (rank : 31)
Query Neighborhood Hits	1031	Target Neighborhood Hits	471	Shared Neighborhood Hits	300
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

GABP2_HUMAN
NC score	0.814824 (rank : 60)	θ value	5.62301e-10 (rank : 151)
Query Neighborhood Hits	1031	Target Neighborhood Hits	454	Shared Neighborhood Hits	289
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ANKS3_MOUSE
NC score	0.814754 (rank : 61)	θ value	6.41864e-14 (rank : 91)
Query Neighborhood Hits	1031	Target Neighborhood Hits	355	Shared Neighborhood Hits	282
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB8_MOUSE
NC score	0.814599 (rank : 62)	θ value	1.53129e-07 (rank : 192)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	281
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

GABP3_MOUSE
NC score	0.814464 (rank : 63)	θ value	7.34386e-10 (rank : 152)
Query Neighborhood Hits	1031	Target Neighborhood Hits	330	Shared Neighborhood Hits	279
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

PP16A_MOUSE
NC score	0.813990 (rank : 64)	θ value	2.88119e-14 (rank : 88)
Query Neighborhood Hits	1031	Target Neighborhood Hits	318	Shared Neighborhood Hits	286
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ANK2_HUMAN
NC score	0.813809 (rank : 65)	θ value	2.96777e-27 (rank : 10)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1615	Shared Neighborhood Hits	598
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASB8_HUMAN
NC score	0.813782 (rank : 66)	θ value	1.99992e-07 (rank : 199)
Query Neighborhood Hits	1031	Target Neighborhood Hits	294	Shared Neighborhood Hits	284
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANKS3_HUMAN
NC score	0.812617 (rank : 67)	θ value	2.20605e-14 (rank : 80)
Query Neighborhood Hits	1031	Target Neighborhood Hits	355	Shared Neighborhood Hits	285
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB16_MOUSE
NC score	0.809679 (rank : 68)	θ value	2.69671e-12 (rank : 113)
Query Neighborhood Hits	1031	Target Neighborhood Hits	306	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

MYPT2_HUMAN
NC score	0.809150 (rank : 69)	θ value	1.74391e-19 (rank : 46)
Query Neighborhood Hits	1031	Target Neighborhood Hits	707	Shared Neighborhood Hits	319
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PP16B_HUMAN
NC score	0.808173 (rank : 70)	θ value	1.80466e-16 (rank : 60)
Query Neighborhood Hits	1031	Target Neighborhood Hits	307	Shared Neighborhood Hits	285
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ANR49_MOUSE
NC score	0.807788 (rank : 71)	θ value	6.87365e-08 (rank : 183)
Query Neighborhood Hits	1031	Target Neighborhood Hits	285	Shared Neighborhood Hits	272
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

CDN2D_HUMAN
NC score	0.807492 (rank : 72)	θ value	2.28291e-11 (rank : 127)
Query Neighborhood Hits	1031	Target Neighborhood Hits	268	Shared Neighborhood Hits	265
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

PP16A_HUMAN
NC score	0.807431 (rank : 73)	θ value	2.69671e-12 (rank : 117)
Query Neighborhood Hits	1031	Target Neighborhood Hits	340	Shared Neighborhood Hits	297
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PP16B_MOUSE
NC score	0.806452 (rank : 74)	θ value	4.74913e-17 (rank : 58)
Query Neighborhood Hits	1031	Target Neighborhood Hits	302	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANKR5_MOUSE
NC score	0.806200 (rank : 75)	θ value	2.88119e-14 (rank : 84)
Query Neighborhood Hits	1031	Target Neighborhood Hits	298	Shared Neighborhood Hits	284
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

PA2G6_HUMAN
NC score	0.805501 (rank : 76)	θ value	1.74796e-11 (rank : 125)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB15_HUMAN
NC score	0.805495 (rank : 77)	θ value	2.20605e-14 (rank : 82)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MIB2_HUMAN
NC score	0.805299 (rank : 78)	θ value	3.63628e-17 (rank : 56)
Query Neighborhood Hits	1031	Target Neighborhood Hits	438	Shared Neighborhood Hits	295
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MYPT1_HUMAN
NC score	0.805105 (rank : 79)	θ value	2.59989e-23 (rank : 25)
Query Neighborhood Hits	1031	Target Neighborhood Hits	723	Shared Neighborhood Hits	318
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MIB2_MOUSE
NC score	0.804098 (rank : 80)	θ value	3.28887e-18 (rank : 53)
Query Neighborhood Hits	1031	Target Neighborhood Hits	409	Shared Neighborhood Hits	289
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANR49_HUMAN
NC score	0.802395 (rank : 81)	θ value	3.77169e-06 (rank : 222)
Query Neighborhood Hits	1031	Target Neighborhood Hits	282	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANKR5_HUMAN
NC score	0.801864 (rank : 82)	θ value	3.18553e-13 (rank : 102)
Query Neighborhood Hits	1031	Target Neighborhood Hits	297	Shared Neighborhood Hits	282
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB9_HUMAN
NC score	0.799944 (rank : 83)	θ value	5.8054e-15 (rank : 77)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	253
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASZ1_HUMAN
NC score	0.799386 (rank : 84)	θ value	1.33837e-11 (rank : 124)
Query Neighborhood Hits	1031	Target Neighborhood Hits	341	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

IKBA_HUMAN
NC score	0.799261 (rank : 85)	θ value	2.69671e-12 (rank : 114)
Query Neighborhood Hits	1031	Target Neighborhood Hits	280	Shared Neighborhood Hits	275
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ASB15_MOUSE
NC score	0.799045 (rank : 86)	θ value	4.74913e-17 (rank : 57)
Query Neighborhood Hits	1031	Target Neighborhood Hits	292	Shared Neighborhood Hits	272
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB16_HUMAN
NC score	0.798839 (rank : 87)	θ value	1.9326e-10 (rank : 143)
Query Neighborhood Hits	1031	Target Neighborhood Hits	286	Shared Neighborhood Hits	271
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

CDN2D_MOUSE
NC score	0.796537 (rank : 88)	θ value	1.38499e-08 (rank : 165)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	265
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB5_HUMAN
NC score	0.795868 (rank : 89)	θ value	6.41864e-14 (rank : 92)
Query Neighborhood Hits	1031	Target Neighborhood Hits	283	Shared Neighborhood Hits	269
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB14_MOUSE
NC score	0.795822 (rank : 90)	θ value	5.43371e-13 (rank : 103)
Query Neighborhood Hits	1031	Target Neighborhood Hits	293	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANRA2_HUMAN
NC score	0.795421 (rank : 91)	θ value	2.28291e-11 (rank : 126)
Query Neighborhood Hits	1031	Target Neighborhood Hits	288	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASZ1_MOUSE
NC score	0.795197 (rank : 92)	θ value	4.0297e-08 (rank : 178)
Query Neighborhood Hits	1031	Target Neighborhood Hits	319	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB5_MOUSE
NC score	0.794142 (rank : 93)	θ value	6.41864e-14 (rank : 93)
Query Neighborhood Hits	1031	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB11_HUMAN
NC score	0.794045 (rank : 94)	θ value	1.42992e-13 (rank : 97)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANRA2_MOUSE
NC score	0.792309 (rank : 95)	θ value	1.133e-10 (rank : 141)
Query Neighborhood Hits	1031	Target Neighborhood Hits	287	Shared Neighborhood Hits	271
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANKR7_HUMAN
NC score	0.791709 (rank : 96)	θ value	3.08544e-08 (rank : 172)
Query Neighborhood Hits	1031	Target Neighborhood Hits	286	Shared Neighborhood Hits	279
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ASB11_MOUSE
NC score	0.790814 (rank : 97)	θ value	3.89403e-11 (rank : 137)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	256
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB9_MOUSE
NC score	0.790687 (rank : 98)	θ value	9.90251e-15 (rank : 78)
Query Neighborhood Hits	1031	Target Neighborhood Hits	257	Shared Neighborhood Hits	250
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MTPN_MOUSE
NC score	0.790472 (rank : 99)	θ value	0.000158464 (rank : 267)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

EHMT1_HUMAN
NC score	0.789598 (rank : 100)	θ value	1.47631e-18 (rank : 52)
Query Neighborhood Hits	1031	Target Neighborhood Hits	417	Shared Neighborhood Hits	312
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

IKBE_MOUSE
NC score	0.788507 (rank : 101)	θ value	1.63604e-09 (rank : 160)
Query Neighborhood Hits	1031	Target Neighborhood Hits	308	Shared Neighborhood Hits	279
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

IKBA_MOUSE
NC score	0.787633 (rank : 102)	θ value	2.98157e-11 (rank : 132)
Query Neighborhood Hits	1031	Target Neighborhood Hits	283	Shared Neighborhood Hits	275
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANR10_MOUSE
NC score	0.786588 (rank : 103)	θ value	3.29651e-10 (rank : 146)
Query Neighborhood Hits	1031	Target Neighborhood Hits	273	Shared Neighborhood Hits	263
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

RFXK_HUMAN
NC score	0.786393 (rank : 104)	θ value	3.08544e-08 (rank : 176)
Query Neighborhood Hits	1031	Target Neighborhood Hits	282	Shared Neighborhood Hits	268
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

CT086_HUMAN
NC score	0.786251 (rank : 105)	θ value	1.43324e-05 (rank : 233)
Query Neighborhood Hits	1031	Target Neighborhood Hits	277	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANR10_HUMAN
NC score	0.786022 (rank : 106)	θ value	1.80886e-08 (rank : 169)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

MTPN_HUMAN
NC score	0.785797 (rank : 107)	θ value	0.000461057 (rank : 280)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ANR46_HUMAN
NC score	0.785007 (rank : 108)	θ value	2.88788e-06 (rank : 221)
Query Neighborhood Hits	1031	Target Neighborhood Hits	281	Shared Neighborhood Hits	276
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

RN5A_HUMAN
NC score	0.781407 (rank : 109)	θ value	3.89403e-11 (rank : 138)
Query Neighborhood Hits	1031	Target Neighborhood Hits	608	Shared Neighborhood Hits	308
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR46_MOUSE
NC score	0.780572 (rank : 110)	θ value	3.41135e-07 (rank : 202)
Query Neighborhood Hits	1031	Target Neighborhood Hits	274	Shared Neighborhood Hits	269
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

AN36B_HUMAN
NC score	0.779943 (rank : 111)	θ value	2.98157e-11 (rank : 129)
Query Neighborhood Hits	1031	Target Neighborhood Hits	294	Shared Neighborhood Hits	280
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

EHMT2_HUMAN
NC score	0.778664 (rank : 112)	θ value	1.99529e-15 (rank : 72)
Query Neighborhood Hits	1031	Target Neighborhood Hits	498	Shared Neighborhood Hits	326
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

BARD1_HUMAN
NC score	0.777790 (rank : 113)	θ value	2.0648e-12 (rank : 110)
Query Neighborhood Hits	1031	Target Neighborhood Hits	427	Shared Neighborhood Hits	293
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB4_HUMAN
NC score	0.777612 (rank : 114)	θ value	3.08544e-08 (rank : 174)
Query Neighborhood Hits	1031	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

EHMT2_MOUSE
NC score	0.777198 (rank : 115)	θ value	1.16975e-15 (rank : 70)
Query Neighborhood Hits	1031	Target Neighborhood Hits	750	Shared Neighborhood Hits	423
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB4_MOUSE
NC score	0.776984 (rank : 116)	θ value	5.26297e-08 (rank : 181)
Query Neighborhood Hits	1031	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ANR22_HUMAN
NC score	0.776603 (rank : 117)	θ value	2.44474e-05 (rank : 243)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	240
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

BARD1_MOUSE
NC score	0.775193 (rank : 118)	θ value	2.0648e-12 (rank : 111)
Query Neighborhood Hits	1031	Target Neighborhood Hits	411	Shared Neighborhood Hits	285
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB12_MOUSE
NC score	0.774223 (rank : 119)	θ value	4.0297e-08 (rank : 177)
Query Neighborhood Hits	1031	Target Neighborhood Hits	261	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ACBD6_MOUSE
NC score	0.771663 (rank : 120)	θ value	8.97725e-08 (rank : 184)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	284
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

IKBE_HUMAN
NC score	0.770936 (rank : 121)	θ value	3.64472e-09 (rank : 163)
Query Neighborhood Hits	1031	Target Neighborhood Hits	288	Shared Neighborhood Hits	274
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ANR35_HUMAN
NC score	0.770616 (rank : 122)	θ value	5.8054e-15 (rank : 76)
Query Neighborhood Hits	1031	Target Neighborhood Hits	784	Shared Neighborhood Hits	316
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

RFXK_MOUSE
NC score	0.769895 (rank : 123)	θ value	9.92553e-07 (rank : 213)
Query Neighborhood Hits	1031	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ASB12_HUMAN
NC score	0.769623 (rank : 124)	θ value	3.08544e-08 (rank : 173)
Query Neighborhood Hits	1031	Target Neighborhood Hits	263	Shared Neighborhood Hits	262
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

IKBB_MOUSE
NC score	0.767833 (rank : 125)	θ value	9.59137e-10 (rank : 155)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ACBD6_HUMAN
NC score	0.767515 (rank : 126)	θ value	1.53129e-07 (rank : 191)
Query Neighborhood Hits	1031	Target Neighborhood Hits	304	Shared Neighborhood Hits	284
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

IKBB_HUMAN
NC score	0.765240 (rank : 127)	θ value	9.59137e-10 (rank : 154)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ANR32_HUMAN
NC score	0.761193 (rank : 128)	θ value	1.63604e-09 (rank : 159)
Query Neighborhood Hits	1031	Target Neighborhood Hits	270	Shared Neighborhood Hits	257
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ASB1_HUMAN
NC score	0.760596 (rank : 129)	θ value	1.43324e-05 (rank : 232)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_MOUSE
NC score	0.760198 (rank : 130)	θ value	1.29631e-06 (rank : 215)
Query Neighborhood Hits	1031	Target Neighborhood Hits	292	Shared Neighborhood Hits	270
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

POTE8_HUMAN
NC score	0.756240 (rank : 131)	θ value	2.20605e-14 (rank : 83)
Query Neighborhood Hits	1031	Target Neighborhood Hits	337	Shared Neighborhood Hits	283
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

USH1G_HUMAN
NC score	0.751657 (rank : 132)	θ value	1.25267e-09 (rank : 156)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	262
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

ANR11_HUMAN
NC score	0.751548 (rank : 133)	θ value	2.20605e-14 (rank : 81)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1289	Shared Neighborhood Hits	447
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

USH1G_MOUSE
NC score	0.751488 (rank : 134)	θ value	1.25267e-09 (rank : 157)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ZDH17_HUMAN
NC score	0.750544 (rank : 135)	θ value	7.0802e-21 (rank : 37)
Query Neighborhood Hits	1031	Target Neighborhood Hits	334	Shared Neighborhood Hits	285
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANR19_HUMAN
NC score	0.748015 (rank : 136)	θ value	1.63604e-09 (rank : 158)
Query Neighborhood Hits	1031	Target Neighborhood Hits	276	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR32_MOUSE
NC score	0.746950 (rank : 137)	θ value	1.99992e-07 (rank : 198)
Query Neighborhood Hits	1031	Target Neighborhood Hits	285	Shared Neighborhood Hits	258
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ZDH17_MOUSE
NC score	0.746074 (rank : 138)	θ value	1.2077e-20 (rank : 40)
Query Neighborhood Hits	1031	Target Neighborhood Hits	328	Shared Neighborhood Hits	279
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANFY1_MOUSE
NC score	0.743767 (rank : 139)	θ value	6.41864e-14 (rank : 90)
Query Neighborhood Hits	1031	Target Neighborhood Hits	480	Shared Neighborhood Hits	294
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.742554 (rank : 140)	θ value	2.43908e-13 (rank : 101)
Query Neighborhood Hits	1031	Target Neighborhood Hits	480	Shared Neighborhood Hits	289
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANS4B_HUMAN
NC score	0.740438 (rank : 141)	θ value	7.59969e-07 (rank : 211)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	262
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

RN5A_MOUSE
NC score	0.738689 (rank : 142)	θ value	1.58096e-12 (rank : 108)
Query Neighborhood Hits	1031	Target Neighborhood Hits	899	Shared Neighborhood Hits	335
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

AN36A_HUMAN
NC score	0.737370 (rank : 143)	θ value	1.29631e-06 (rank : 214)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	268
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ZDH13_MOUSE
NC score	0.736515 (rank : 144)	θ value	1.52774e-15 (rank : 71)
Query Neighborhood Hits	1031	Target Neighborhood Hits	329	Shared Neighborhood Hits	284
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ZDH13_HUMAN
NC score	0.734790 (rank : 145)	θ value	8.38298e-14 (rank : 96)
Query Neighborhood Hits	1031	Target Neighborhood Hits	322	Shared Neighborhood Hits	280
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

SHAN1_HUMAN
NC score	0.734368 (rank : 146)	θ value	3.64472e-09 (rank : 164)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1041	Shared Neighborhood Hits	515
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

CTTB2_HUMAN
NC score	0.734362 (rank : 147)	θ value	1.63225e-17 (rank : 55)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1061	Shared Neighborhood Hits	382
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR15_HUMAN
NC score	0.731569 (rank : 148)	θ value	1.86753e-13 (rank : 99)
Query Neighborhood Hits	1031	Target Neighborhood Hits	478	Shared Neighborhood Hits	295
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR41_HUMAN
NC score	0.729994 (rank : 149)	θ value	4.1701e-05 (rank : 249)
Query Neighborhood Hits	1031	Target Neighborhood Hits	332	Shared Neighborhood Hits	273
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR47_MOUSE
NC score	0.727878 (rank : 150)	θ value	3.52202e-12 (rank : 118)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	273
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANS4B_MOUSE
NC score	0.727455 (rank : 151)	θ value	1.69304e-06 (rank : 217)
Query Neighborhood Hits	1031	Target Neighborhood Hits	294	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANKY2_HUMAN
NC score	0.724938 (rank : 152)	θ value	3.41135e-07 (rank : 201)
Query Neighborhood Hits	1031	Target Neighborhood Hits	306	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR37_HUMAN
NC score	0.717756 (rank : 153)	θ value	1.87187e-05 (rank : 236)
Query Neighborhood Hits	1031	Target Neighborhood Hits	247	Shared Neighborhood Hits	244
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANR21_HUMAN
NC score	0.712471 (rank : 154)	θ value	4.44505e-15 (rank : 75)
Query Neighborhood Hits	1031	Target Neighborhood Hits	864	Shared Neighborhood Hits	319
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT15_HUMAN
NC score	0.711087 (rank : 155)	θ value	8.38298e-14 (rank : 95)
Query Neighborhood Hits	1031	Target Neighborhood Hits	893	Shared Neighborhood Hits	317
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

NFKB1_HUMAN
NC score	0.709391 (rank : 156)	θ value	2.88119e-14 (rank : 87)
Query Neighborhood Hits	1031	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NFKB1_MOUSE
NC score	0.707924 (rank : 157)	θ value	2.0648e-12 (rank : 112)
Query Neighborhood Hits	1031	Target Neighborhood Hits	300	Shared Neighborhood Hits	273
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANR12_HUMAN
NC score	0.705137 (rank : 158)	θ value	2.88119e-14 (rank : 85)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1081	Shared Neighborhood Hits	333
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR47_HUMAN
NC score	0.704793 (rank : 159)	θ value	3.64472e-09 (rank : 162)
Query Neighborhood Hits	1031	Target Neighborhood Hits	369	Shared Neighborhood Hits	271
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANKY2_MOUSE
NC score	0.703959 (rank : 160)	θ value	8.97725e-08 (rank : 185)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	259
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

SNCAP_HUMAN
NC score	0.701580 (rank : 161)	θ value	0.000270298 (rank : 276)
Query Neighborhood Hits	1031	Target Neighborhood Hits	313	Shared Neighborhood Hits	255
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

BCOR_MOUSE
NC score	0.701236 (rank : 162)	θ value	1.53129e-07 (rank : 193)
Query Neighborhood Hits	1031	Target Neighborhood Hits	521	Shared Neighborhood Hits	336
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR37_MOUSE
NC score	0.701211 (rank : 163)	θ value	6.43352e-06 (rank : 225)
Query Neighborhood Hits	1031	Target Neighborhood Hits	237	Shared Neighborhood Hits	234
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

NFKB2_HUMAN
NC score	0.699793 (rank : 164)	θ value	8.67504e-11 (rank : 140)
Query Neighborhood Hits	1031	Target Neighborhood Hits	325	Shared Neighborhood Hits	280
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

POT14_HUMAN
NC score	0.697617 (rank : 165)	θ value	1.02475e-11 (rank : 123)
Query Neighborhood Hits	1031	Target Neighborhood Hits	403	Shared Neighborhood Hits	280
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

BCOR_HUMAN
NC score	0.696375 (rank : 166)	θ value	3.41135e-07 (rank : 203)
Query Neighborhood Hits	1031	Target Neighborhood Hits	609	Shared Neighborhood Hits	370
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

KRIT1_MOUSE
NC score	0.692954 (rank : 167)	θ value	2.98157e-11 (rank : 133)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	230
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

ANR25_HUMAN
NC score	0.687442 (rank : 168)	θ value	5.62301e-10 (rank : 149)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	283
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ASB6_HUMAN
NC score	0.684766 (rank : 169)	θ value	0.0113563 (rank : 341)
Query Neighborhood Hits	1031	Target Neighborhood Hits	256	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

NFKB2_MOUSE
NC score	0.684007 (rank : 170)	θ value	1.9326e-10 (rank : 144)
Query Neighborhood Hits	1031	Target Neighborhood Hits	326	Shared Neighborhood Hits	279
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

KRIT1_HUMAN
NC score	0.683309 (rank : 171)	θ value	7.84624e-12 (rank : 122)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ANR33_MOUSE
NC score	0.683198 (rank : 172)	θ value	7.59969e-07 (rank : 210)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	223
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CD2A1_MOUSE
NC score	0.680927 (rank : 173)	θ value	5.44631e-05 (rank : 255)
Query Neighborhood Hits	1031	Target Neighborhood Hits	206	Shared Neighborhood Hits	203
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ASB6_MOUSE
NC score	0.679234 (rank : 174)	θ value	0.0113563 (rank : 342)
Query Neighborhood Hits	1031	Target Neighborhood Hits	264	Shared Neighborhood Hits	244
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR25_MOUSE
NC score	0.678220 (rank : 175)	θ value	2.13673e-09 (rank : 161)
Query Neighborhood Hits	1031	Target Neighborhood Hits	398	Shared Neighborhood Hits	300
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR38_HUMAN
NC score	0.670791 (rank : 176)	θ value	5.62301e-10 (rank : 150)
Query Neighborhood Hits	1031	Target Neighborhood Hits	443	Shared Neighborhood Hits	269
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

OSBL1_HUMAN
NC score	0.660972 (rank : 177)	θ value	4.02038e-16 (rank : 65)
Query Neighborhood Hits	1031	Target Neighborhood Hits	368	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR33_HUMAN
NC score	0.659729 (rank : 178)	θ value	0.000158464 (rank : 266)
Query Neighborhood Hits	1031	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

POT22_HUMAN
NC score	0.657969 (rank : 179)	θ value	1.53129e-07 (rank : 195)
Query Neighborhood Hits	1031	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

MPP8_HUMAN
NC score	0.649760 (rank : 180)	θ value	4.45536e-07 (rank : 205)
Query Neighborhood Hits	1031	Target Neighborhood Hits	948	Shared Neighborhood Hits	308
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

OSBL1_MOUSE
NC score	0.648575 (rank : 181)	θ value	5.25075e-16 (rank : 67)
Query Neighborhood Hits	1031	Target Neighborhood Hits	336	Shared Neighborhood Hits	281
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSTF1_MOUSE
NC score	0.647785 (rank : 182)	θ value	1.38499e-08 (rank : 168)
Query Neighborhood Hits	1031	Target Neighborhood Hits	467	Shared Neighborhood Hits	298
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ANR38_MOUSE
NC score	0.647407 (rank : 183)	θ value	9.59137e-10 (rank : 153)
Query Neighborhood Hits	1031	Target Neighborhood Hits	512	Shared Neighborhood Hits	270
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CLPB_MOUSE
NC score	0.643567 (rank : 184)	θ value	0.00298849 (rank : 311)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	252
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CDN2B_MOUSE
NC score	0.637959 (rank : 185)	θ value	0.00869519 (rank : 333)
Query Neighborhood Hits	1031	Target Neighborhood Hits	201	Shared Neighborhood Hits	199
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

A20A3_HUMAN
NC score	0.636178 (rank : 186)	θ value	1.53129e-07 (rank : 189)
Query Neighborhood Hits	1031	Target Neighborhood Hits	692	Shared Neighborhood Hits	297
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.635662 (rank : 187)	θ value	6.87365e-08 (rank : 182)
Query Neighborhood Hits	1031	Target Neighborhood Hits	716	Shared Neighborhood Hits	302
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.634705 (rank : 188)	θ value	1.17247e-07 (rank : 188)
Query Neighborhood Hits	1031	Target Neighborhood Hits	698	Shared Neighborhood Hits	293
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A4_HUMAN
NC score	0.631632 (rank : 189)	θ value	1.53129e-07 (rank : 190)
Query Neighborhood Hits	1031	Target Neighborhood Hits	710	Shared Neighborhood Hits	298
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

RAI14_HUMAN
NC score	0.630709 (rank : 190)	θ value	1.2077e-20 (rank : 39)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1367	Shared Neighborhood Hits	373
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

OSTF1_HUMAN
NC score	0.630557 (rank : 191)	θ value	8.97725e-08 (rank : 187)
Query Neighborhood Hits	1031	Target Neighborhood Hits	466	Shared Neighborhood Hits	296
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

CD2A1_HUMAN
NC score	0.609898 (rank : 192)	θ value	5.44631e-05 (rank : 254)
Query Neighborhood Hits	1031	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ANR18_HUMAN
NC score	0.600202 (rank : 193)	θ value	4.59992e-12 (rank : 119)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1106	Shared Neighborhood Hits	320
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

RAI14_MOUSE
NC score	0.599643 (rank : 194)	θ value	7.0802e-21 (rank : 36)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1505	Shared Neighborhood Hits	382
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR45_MOUSE
NC score	0.598083 (rank : 195)	θ value	0.00035302 (rank : 277)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

CDN2B_HUMAN
NC score	0.591216 (rank : 196)	θ value	0.00298849 (rank : 309)
Query Neighborhood Hits	1031	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ANR43_HUMAN
NC score	0.590362 (rank : 197)	θ value	0.00509761 (rank : 321)
Query Neighborhood Hits	1031	Target Neighborhood Hits	209	Shared Neighborhood Hits	200
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_MOUSE
NC score	0.589835 (rank : 198)	θ value	0.00298849 (rank : 308)
Query Neighborhood Hits	1031	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

HECD1_HUMAN
NC score	0.587973 (rank : 199)	θ value	3.41135e-07 (rank : 204)
Query Neighborhood Hits	1031	Target Neighborhood Hits	371	Shared Neighborhood Hits	277
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ANKK1_HUMAN
NC score	0.579871 (rank : 200)	θ value	8.08199e-25 (rank : 15)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1075	Shared Neighborhood Hits	356
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

RIPK4_HUMAN
NC score	0.578181 (rank : 201)	θ value	3.50572e-28 (rank : 8)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1094	Shared Neighborhood Hits	362
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

AN30A_HUMAN
NC score	0.573005 (rank : 202)	θ value	2.0648e-12 (rank : 109)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1119	Shared Neighborhood Hits	348
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ABTB2_HUMAN
NC score	0.571809 (rank : 203)	θ value	1.99992e-07 (rank : 196)
Query Neighborhood Hits	1031	Target Neighborhood Hits	391	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP2_HUMAN
NC score	0.567524 (rank : 204)	θ value	5.81887e-07 (rank : 207)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1156	Shared Neighborhood Hits	432
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANKK1_MOUSE
NC score	0.566417 (rank : 205)	θ value	8.08199e-25 (rank : 16)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1072	Shared Neighborhood Hits	354
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

IASPP_HUMAN
NC score	0.566257 (rank : 206)	θ value	0.0193708 (rank : 358)
Query Neighborhood Hits	1031	Target Neighborhood Hits	688	Shared Neighborhood Hits	420
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ABTB2_MOUSE
NC score	0.560070 (rank : 207)	θ value	5.26297e-08 (rank : 179)
Query Neighborhood Hits	1031	Target Neighborhood Hits	414	Shared Neighborhood Hits	234
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ASPP1_MOUSE
NC score	0.557684 (rank : 208)	θ value	1.87187e-05 (rank : 237)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1244	Shared Neighborhood Hits	520
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CLPB_HUMAN
NC score	0.557609 (rank : 209)	θ value	0.0252991 (rank : 363)
Query Neighborhood Hits	1031	Target Neighborhood Hits	265	Shared Neighborhood Hits	234
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ASPP1_HUMAN
NC score	0.556450 (rank : 210)	θ value	3.19293e-05 (rank : 244)
Query Neighborhood Hits	1031	Target Neighborhood Hits	956	Shared Neighborhood Hits	395
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

NUD12_MOUSE
NC score	0.553589 (rank : 211)	θ value	0.00390308 (rank : 316)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	219
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ILK2_HUMAN
NC score	0.552813 (rank : 212)	θ value	2.69671e-12 (rank : 116)
Query Neighborhood Hits	1031	Target Neighborhood Hits	848	Shared Neighborhood Hits	327
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ANR45_HUMAN
NC score	0.542860 (rank : 213)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	1031	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

IASPP_MOUSE
NC score	0.538728 (rank : 214)	θ value	0.0330416 (rank : 375)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1024	Shared Neighborhood Hits	538
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ILK1_HUMAN
NC score	0.535700 (rank : 215)	θ value	2.69671e-12 (rank : 115)
Query Neighborhood Hits	1031	Target Neighborhood Hits	857	Shared Neighborhood Hits	327
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK_MOUSE
NC score	0.534904 (rank : 216)	θ value	1.58096e-12 (rank : 107)
Query Neighborhood Hits	1031	Target Neighborhood Hits	858	Shared Neighborhood Hits	327
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ANR40_HUMAN
NC score	0.532967 (rank : 217)	θ value	8.99809 (rank : 973)
Query Neighborhood Hits	1031	Target Neighborhood Hits	224	Shared Neighborhood Hits	211
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CENB5_HUMAN
NC score	0.532086 (rank : 218)	θ value	0.000270298 (rank : 273)
Query Neighborhood Hits	1031	Target Neighborhood Hits	395	Shared Neighborhood Hits	272
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ANR40_MOUSE
NC score	0.531252 (rank : 219)	θ value	6.88961 (rank : 914)
Query Neighborhood Hits	1031	Target Neighborhood Hits	228	Shared Neighborhood Hits	214
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

TRPV6_MOUSE
NC score	0.530864 (rank : 220)	θ value	3.19293e-05 (rank : 247)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

AN13B_MOUSE
NC score	0.525794 (rank : 221)	θ value	2.88788e-06 (rank : 220)
Query Neighborhood Hits	1031	Target Neighborhood Hits	276	Shared Neighborhood Hits	255
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.524925 (rank : 222)	θ value	2.88788e-06 (rank : 219)
Query Neighborhood Hits	1031	Target Neighborhood Hits	265	Shared Neighborhood Hits	253
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CENB1_HUMAN
NC score	0.522068 (rank : 223)	θ value	0.0252991 (rank : 362)
Query Neighborhood Hits	1031	Target Neighborhood Hits	383	Shared Neighborhood Hits	272
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
NC score	0.518848 (rank : 224)	θ value	3.19293e-05 (rank : 245)
Query Neighborhood Hits	1031	Target Neighborhood Hits	425	Shared Neighborhood Hits	265
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ANKY1_HUMAN
NC score	0.517091 (rank : 225)	θ value	0.163984 (rank : 447)
Query Neighborhood Hits	1031	Target Neighborhood Hits	248	Shared Neighborhood Hits	208
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

NUD12_HUMAN
NC score	0.516383 (rank : 226)	θ value	0.0431538 (rank : 389)
Query Neighborhood Hits	1031	Target Neighborhood Hits	222	Shared Neighborhood Hits	198
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ASB14_HUMAN
NC score	0.511046 (rank : 227)	θ value	0.279714 (rank : 484)
Query Neighborhood Hits	1031	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

AN13C_HUMAN
NC score	0.510507 (rank : 228)	θ value	0.00390308 (rank : 312)
Query Neighborhood Hits	1031	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GLSL_HUMAN
NC score	0.507425 (rank : 229)	θ value	0.00134147 (rank : 292)
Query Neighborhood Hits	1031	Target Neighborhood Hits	211	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GLSL_MOUSE
NC score	0.503683 (rank : 230)	θ value	0.000786445 (rank : 287)
Query Neighborhood Hits	1031	Target Neighborhood Hits	212	Shared Neighborhood Hits	202
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

AN13C_MOUSE
NC score	0.501637 (rank : 231)	θ value	0.00228821 (rank : 302)
Query Neighborhood Hits	1031	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GIT2_MOUSE
NC score	0.499182 (rank : 232)	θ value	0.00020696 (rank : 271)
Query Neighborhood Hits	1031	Target Neighborhood Hits	323	Shared Neighborhood Hits	263
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

UACA_HUMAN
NC score	0.487983 (rank : 233)	θ value	6.64225e-11 (rank : 139)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1622	Shared Neighborhood Hits	366
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

TRPV5_MOUSE
NC score	0.484844 (rank : 234)	θ value	1.87187e-05 (rank : 241)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	246
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

GIT1_MOUSE
NC score	0.482535 (rank : 235)	θ value	4.1701e-05 (rank : 253)
Query Neighborhood Hits	1031	Target Neighborhood Hits	341	Shared Neighborhood Hits	254
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.481576 (rank : 236)	θ value	4.1701e-05 (rank : 252)
Query Neighborhood Hits	1031	Target Neighborhood Hits	336	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

TNI3K_HUMAN
NC score	0.469641 (rank : 237)	θ value	5.79196e-23 (rank : 28)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1084	Shared Neighborhood Hits	354
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CT012_MOUSE
NC score	0.469194 (rank : 238)	θ value	6.43352e-06 (rank : 226)
Query Neighborhood Hits	1031	Target Neighborhood Hits	229	Shared Neighborhood Hits	182
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

DDFL1_MOUSE
NC score	0.467330 (rank : 239)	θ value	7.1131e-05 (rank : 258)
Query Neighborhood Hits	1031	Target Neighborhood Hits	324	Shared Neighborhood Hits	260
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GIT2_HUMAN
NC score	0.464823 (rank : 240)	θ value	0.000121331 (rank : 263)
Query Neighborhood Hits	1031	Target Neighborhood Hits	381	Shared Neighborhood Hits	261
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GLSK_HUMAN
NC score	0.464460 (rank : 241)	θ value	0.0330416 (rank : 373)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

TNI3K_MOUSE
NC score	0.463968 (rank : 242)	θ value	2.43343e-21 (rank : 35)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1079	Shared Neighborhood Hits	355
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

UACA_MOUSE
NC score	0.462495 (rank : 243)	θ value	2.52405e-10 (rank : 145)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1620	Shared Neighborhood Hits	368
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

AN13A_HUMAN
NC score	0.461963 (rank : 244)	θ value	2.44474e-05 (rank : 242)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	223
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

NOTC4_MOUSE
NC score	0.458845 (rank : 245)	θ value	8.95645e-16 (rank : 69)
Query Neighborhood Hits	1031	Target Neighborhood Hits	872	Shared Neighborhood Hits	319
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_HUMAN
NC score	0.455140 (rank : 246)	θ value	6.20254e-17 (rank : 59)
Query Neighborhood Hits	1031	Target Neighborhood Hits	905	Shared Neighborhood Hits	332
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRPV6_HUMAN
NC score	0.447444 (rank : 247)	θ value	0.00390308 (rank : 317)
Query Neighborhood Hits	1031	Target Neighborhood Hits	262	Shared Neighborhood Hits	225
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV5_HUMAN
NC score	0.443686 (rank : 248)	θ value	0.0961366 (rank : 428)
Query Neighborhood Hits	1031	Target Neighborhood Hits	261	Shared Neighborhood Hits	224
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ANR26_MOUSE
NC score	0.443356 (rank : 249)	θ value	5.26297e-08 (rank : 180)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1554	Shared Neighborhood Hits	362
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN13A_MOUSE
NC score	0.438421 (rank : 250)	θ value	0.00020696 (rank : 268)
Query Neighborhood Hits	1031	Target Neighborhood Hits	226	Shared Neighborhood Hits	214
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

CT012_HUMAN
NC score	0.427724 (rank : 251)	θ value	0.000602161 (rank : 282)
Query Neighborhood Hits	1031	Target Neighborhood Hits	205	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

ANR26_HUMAN
NC score	0.423722 (rank : 252)	θ value	1.99992e-07 (rank : 197)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1614	Shared Neighborhood Hits	364
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC3_MOUSE
NC score	0.416283 (rank : 253)	θ value	9.26847e-13 (rank : 106)
Query Neighborhood Hits	1031	Target Neighborhood Hits	975	Shared Neighborhood Hits	358
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.416262 (rank : 254)	θ value	5.43371e-13 (rank : 104)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1062	Shared Neighborhood Hits	396
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.414543 (rank : 255)	θ value	2.28291e-11 (rank : 128)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1113	Shared Neighborhood Hits	446
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DAPK1_MOUSE
NC score	0.414339 (rank : 256)	θ value	2.35151e-24 (rank : 19)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1138	Shared Neighborhood Hits	360
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DDEF2_HUMAN
NC score	0.413577 (rank : 257)	θ value	5.44631e-05 (rank : 256)
Query Neighborhood Hits	1031	Target Neighborhood Hits	599	Shared Neighborhood Hits	338
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

TEX14_HUMAN
NC score	0.411879 (rank : 258)	θ value	0.00228821 (rank : 306)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1103	Shared Neighborhood Hits	340
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

NOTC2_MOUSE
NC score	0.410106 (rank : 259)	θ value	2.98157e-11 (rank : 135)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1069	Shared Neighborhood Hits	414
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DDEF2_MOUSE
NC score	0.409927 (rank : 260)	θ value	5.44631e-05 (rank : 257)
Query Neighborhood Hits	1031	Target Neighborhood Hits	625	Shared Neighborhood Hits	351
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

TEX14_MOUSE
NC score	0.409352 (rank : 261)	θ value	0.000602161 (rank : 284)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1333	Shared Neighborhood Hits	349
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

NOTC1_HUMAN
NC score	0.408462 (rank : 262)	θ value	4.59992e-12 (rank : 121)
Query Neighborhood Hits	1031	Target Neighborhood Hits	906	Shared Neighborhood Hits	320
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DAPK1_HUMAN
NC score	0.406181 (rank : 263)	θ value	1.5242e-23 (rank : 23)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1130	Shared Neighborhood Hits	354
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DDFL1_HUMAN
NC score	0.376590 (rank : 264)	θ value	0.000602161 (rank : 283)
Query Neighborhood Hits	1031	Target Neighborhood Hits	353	Shared Neighborhood Hits	252
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKZ_HUMAN
NC score	0.367088 (rank : 265)	θ value	0.0113563 (rank : 346)
Query Neighborhood Hits	1031	Target Neighborhood Hits	551	Shared Neighborhood Hits	221
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG1_MOUSE
NC score	0.350611 (rank : 266)	θ value	0.00509761 (rank : 322)
Query Neighborhood Hits	1031	Target Neighborhood Hits	531	Shared Neighborhood Hits	300
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

NOTC1_MOUSE
NC score	0.350428 (rank : 267)	θ value	3.29651e-10 (rank : 147)
Query Neighborhood Hits	1031	Target Neighborhood Hits	916	Shared Neighborhood Hits	312
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DGKI_HUMAN
NC score	0.350207 (rank : 268)	θ value	6.43352e-06 (rank : 227)
Query Neighborhood Hits	1031	Target Neighborhood Hits	609	Shared Neighborhood Hits	226
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

DGKZ_MOUSE
NC score	0.349987 (rank : 269)	θ value	0.00228821 (rank : 303)
Query Neighborhood Hits	1031	Target Neighborhood Hits	542	Shared Neighborhood Hits	210
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG1_HUMAN
NC score	0.348036 (rank : 270)	θ value	0.00665767 (rank : 327)
Query Neighborhood Hits	1031	Target Neighborhood Hits	544	Shared Neighborhood Hits	303
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG2_HUMAN
NC score	0.337765 (rank : 271)	θ value	0.00298849 (rank : 310)
Query Neighborhood Hits	1031	Target Neighborhood Hits	471	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

ANKZ1_MOUSE
NC score	0.336938 (rank : 272)	θ value	0.279714 (rank : 483)
Query Neighborhood Hits	1031	Target Neighborhood Hits	208	Shared Neighborhood Hits	157
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CENG2_MOUSE
NC score	0.335049 (rank : 273)	θ value	0.00665767 (rank : 328)
Query Neighborhood Hits	1031	Target Neighborhood Hits	463	Shared Neighborhood Hits	261
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DDEF1_MOUSE
NC score	0.328369 (rank : 274)	θ value	0.00020696 (rank : 269)
Query Neighborhood Hits	1031	Target Neighborhood Hits	592	Shared Neighborhood Hits	306
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

IKBL_HUMAN
NC score	0.323059 (rank : 275)	θ value	0.163984 (rank : 453)
Query Neighborhood Hits	1031	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ANKZ1_HUMAN
NC score	0.318357 (rank : 276)	θ value	0.21417 (rank : 467)
Query Neighborhood Hits	1031	Target Neighborhood Hits	236	Shared Neighborhood Hits	164
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

IKBL_MOUSE
NC score	0.315465 (rank : 277)	θ value	0.163984 (rank : 454)
Query Neighborhood Hits	1031	Target Neighborhood Hits	196	Shared Neighborhood Hits	140
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CLR59_HUMAN
NC score	0.310161 (rank : 278)	θ value	0.00390308 (rank : 313)
Query Neighborhood Hits	1031	Target Neighborhood Hits	163	Shared Neighborhood Hits	145
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CENG3_HUMAN
NC score	0.306462 (rank : 279)	θ value	5.27518 (rank : 862)
Query Neighborhood Hits	1031	Target Neighborhood Hits	455	Shared Neighborhood Hits	239
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
NC score	0.306400 (rank : 280)	θ value	5.27518 (rank : 863)
Query Neighborhood Hits	1031	Target Neighborhood Hits	467	Shared Neighborhood Hits	243
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ABTB1_MOUSE
NC score	0.270556 (rank : 281)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	1031	Target Neighborhood Hits	349	Shared Neighborhood Hits	176
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

RSNL2_HUMAN
NC score	0.266049 (rank : 282)	θ value	1.43324e-05 (rank : 235)
Query Neighborhood Hits	1031	Target Neighborhood Hits	136	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

ANKR9_MOUSE
NC score	0.257109 (rank : 283)	θ value	8.99809 (rank : 972)
Query Neighborhood Hits	1031	Target Neighborhood Hits	120	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BAT4_MOUSE
NC score	0.243330 (rank : 284)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	1031	Target Neighborhood Hits	171	Shared Neighborhood Hits	125
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

TRPV1_MOUSE
NC score	0.238516 (rank : 285)	θ value	0.00175202 (rank : 300)
Query Neighborhood Hits	1031	Target Neighborhood Hits	189	Shared Neighborhood Hits	154
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ABTB1_HUMAN
NC score	0.229231 (rank : 286)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	1031	Target Neighborhood Hits	325	Shared Neighborhood Hits	160
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

RSNL2_MOUSE
NC score	0.227006 (rank : 287)	θ value	0.000461057 (rank : 281)
Query Neighborhood Hits	1031	Target Neighborhood Hits	129	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV3_HUMAN
NC score	0.223081 (rank : 288)	θ value	6.88961 (rank : 967)
Query Neighborhood Hits	1031	Target Neighborhood Hits	198	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.222919 (rank : 289)	θ value	θ > 10 (rank : 1301)
Query Neighborhood Hits	1031	Target Neighborhood Hits	188	Shared Neighborhood Hits	132
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_HUMAN
NC score	0.216399 (rank : 290)	θ value	0.365318 (rank : 512)
Query Neighborhood Hits	1031	Target Neighborhood Hits	184	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV2_HUMAN
NC score	0.213825 (rank : 291)	θ value	0.00869519 (rank : 338)
Query Neighborhood Hits	1031	Target Neighborhood Hits	130	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

BAT4_HUMAN
NC score	0.212296 (rank : 292)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	1031	Target Neighborhood Hits	157	Shared Neighborhood Hits	111
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CMTA1_HUMAN
NC score	0.211509 (rank : 293)	θ value	0.125558 (rank : 436)
Query Neighborhood Hits	1031	Target Neighborhood Hits	217	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

ANKR9_HUMAN
NC score	0.206721 (rank : 294)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	1031	Target Neighborhood Hits	99	Shared Neighborhood Hits	97
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

WASIP_HUMAN
NC score	0.197539 (rank : 295)	θ value	0.00228821 (rank : 307)
Query Neighborhood Hits	1031	Target Neighborhood Hits	458	Shared Neighborhood Hits	222
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CMTA2_HUMAN
NC score	0.190087 (rank : 296)	θ value	0.0330416 (rank : 368)
Query Neighborhood Hits	1031	Target Neighborhood Hits	199	Shared Neighborhood Hits	132
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

NACAM_MOUSE
NC score	0.186702 (rank : 297)	θ value	6.43352e-06 (rank : 229)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1866	Shared Neighborhood Hits	501
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRRT3_HUMAN
NC score	0.183280 (rank : 298)	θ value	2.21117e-06 (rank : 218)
Query Neighborhood Hits	1031	Target Neighborhood Hits	998	Shared Neighborhood Hits	381
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CMTA2_MOUSE
NC score	0.179021 (rank : 299)	θ value	0.0330416 (rank : 369)
Query Neighborhood Hits	1031	Target Neighborhood Hits	216	Shared Neighborhood Hits	128
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

PRP1_HUMAN
NC score	0.175255 (rank : 300)	θ value	0.00175202 (rank : 298)
Query Neighborhood Hits	1031	Target Neighborhood Hits	385	Shared Neighborhood Hits	178
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

WASIP_MOUSE
NC score	0.174503 (rank : 301)	θ value	0.00390308 (rank : 318)
Query Neighborhood Hits	1031	Target Neighborhood Hits	392	Shared Neighborhood Hits	205
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

MUC1_HUMAN
NC score	0.174380 (rank : 302)	θ value	2.98157e-11 (rank : 134)
Query Neighborhood Hits	1031	Target Neighborhood Hits	975	Shared Neighborhood Hits	346
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PRP2_MOUSE
NC score	0.173804 (rank : 303)	θ value	0.21417 (rank : 471)
Query Neighborhood Hits	1031	Target Neighborhood Hits	347	Shared Neighborhood Hits	174
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

NCOA6_HUMAN
NC score	0.173201 (rank : 304)	θ value	9.29e-05 (rank : 261)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1202	Shared Neighborhood Hits	407
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

OGFR_HUMAN
NC score	0.171743 (rank : 305)	θ value	1.09739e-05 (rank : 231)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1582	Shared Neighborhood Hits	455
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TRPV2_MOUSE
NC score	0.169662 (rank : 306)	θ value	0.0431538 (rank : 390)
Query Neighborhood Hits	1031	Target Neighborhood Hits	111	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

SRRM1_MOUSE
NC score	0.168197 (rank : 307)	θ value	0.0736092 (rank : 411)
Query Neighborhood Hits	1031	Target Neighborhood Hits	966	Shared Neighborhood Hits	330
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MDC1_HUMAN
NC score	0.165407 (rank : 308)	θ value	9.29e-05 (rank : 260)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1446	Shared Neighborhood Hits	368
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TARSH_HUMAN
NC score	0.162576 (rank : 309)	θ value	0.0563607 (rank : 402)
Query Neighborhood Hits	1031	Target Neighborhood Hits	768	Shared Neighborhood Hits	314
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

GSCR1_HUMAN
NC score	0.160171 (rank : 310)	θ value	0.125558 (rank : 438)
Query Neighborhood Hits	1031	Target Neighborhood Hits	674	Shared Neighborhood Hits	290
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

NCOA6_MOUSE
NC score	0.160050 (rank : 311)	θ value	7.1131e-05 (rank : 259)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1076	Shared Neighborhood Hits	368
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SON_HUMAN
NC score	0.159820 (rank : 312)	θ value	4.45536e-07 (rank : 206)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1568	Shared Neighborhood Hits	447
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PRR12_HUMAN
NC score	0.159692 (rank : 313)	θ value	0.0961366 (rank : 420)
Query Neighborhood Hits	1031	Target Neighborhood Hits	460	Shared Neighborhood Hits	215
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

BSN_MOUSE
NC score	0.159418 (rank : 314)	θ value	0.0113563 (rank : 345)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2057	Shared Neighborhood Hits	512
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PRB4S_HUMAN
NC score	0.155222 (rank : 315)	θ value	0.0330416 (rank : 377)
Query Neighborhood Hits	1031	Target Neighborhood Hits	330	Shared Neighborhood Hits	146
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

WIRE_MOUSE
NC score	0.154101 (rank : 316)	θ value	0.0736092 (rank : 413)
Query Neighborhood Hits	1031	Target Neighborhood Hits	310	Shared Neighborhood Hits	167
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

SRRM1_HUMAN
NC score	0.152892 (rank : 317)	θ value	0.813845 (rank : 593)
Query Neighborhood Hits	1031	Target Neighborhood Hits	690	Shared Neighborhood Hits	228
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MDC1_MOUSE
NC score	0.152714 (rank : 318)	θ value	6.43352e-06 (rank : 228)
Query Neighborhood Hits	1031	Target Neighborhood Hits	998	Shared Neighborhood Hits	316
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BAT2_HUMAN
NC score	0.151620 (rank : 319)	θ value	0.0113563 (rank : 343)
Query Neighborhood Hits	1031	Target Neighborhood Hits	931	Shared Neighborhood Hits	340
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

WIRE_HUMAN
NC score	0.149508 (rank : 320)	θ value	0.813845 (rank : 598)
Query Neighborhood Hits	1031	Target Neighborhood Hits	329	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

PRB3_HUMAN
NC score	0.149170 (rank : 321)	θ value	0.0193708 (rank : 360)
Query Neighborhood Hits	1031	Target Neighborhood Hits	318	Shared Neighborhood Hits	154
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

BCL9_HUMAN
NC score	0.148804 (rank : 322)	θ value	0.00134147 (rank : 290)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1008	Shared Neighborhood Hits	358
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MUC7_HUMAN
NC score	0.147637 (rank : 323)	θ value	1.38821 (rank : 647)
Query Neighborhood Hits	1031	Target Neighborhood Hits	538	Shared Neighborhood Hits	216
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

RGS3_MOUSE
NC score	0.144650 (rank : 324)	θ value	7.59969e-07 (rank : 212)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1621	Shared Neighborhood Hits	439
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PCLO_HUMAN
NC score	0.144288 (rank : 325)	θ value	0.000270298 (rank : 275)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2046	Shared Neighborhood Hits	482
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MLL3_HUMAN
NC score	0.142817 (rank : 326)	θ value	1.43324e-05 (rank : 234)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1644	Shared Neighborhood Hits	403
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PCLO_MOUSE
NC score	0.141660 (rank : 327)	θ value	0.000121331 (rank : 264)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2275	Shared Neighborhood Hits	522
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

BSN_HUMAN
NC score	0.140594 (rank : 328)	θ value	0.0113563 (rank : 344)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1537	Shared Neighborhood Hits	414
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PRG4_HUMAN
NC score	0.140448 (rank : 329)	θ value	0.21417 (rank : 470)
Query Neighborhood Hits	1031	Target Neighborhood Hits	764	Shared Neighborhood Hits	257
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WBP11_MOUSE
NC score	0.138760 (rank : 330)	θ value	0.00390308 (rank : 320)
Query Neighborhood Hits	1031	Target Neighborhood Hits	362	Shared Neighborhood Hits	153
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBP11_HUMAN
NC score	0.138486 (rank : 331)	θ value	0.00390308 (rank : 319)
Query Neighborhood Hits	1031	Target Neighborhood Hits	354	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

MAGE1_HUMAN
NC score	0.137696 (rank : 332)	θ value	0.00134147 (rank : 293)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1389	Shared Neighborhood Hits	420
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BCL9_MOUSE
NC score	0.137432 (rank : 333)	θ value	0.0148317 (rank : 351)
Query Neighborhood Hits	1031	Target Neighborhood Hits	770	Shared Neighborhood Hits	308
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

ATN1_HUMAN
NC score	0.137167 (rank : 334)	θ value	0.00102713 (rank : 288)
Query Neighborhood Hits	1031	Target Neighborhood Hits	676	Shared Neighborhood Hits	228
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAT2_MOUSE
NC score	0.137061 (rank : 335)	θ value	0.365318 (rank : 498)
Query Neighborhood Hits	1031	Target Neighborhood Hits	947	Shared Neighborhood Hits	352
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SASH1_MOUSE
NC score	0.136758 (rank : 336)	θ value	0.00134147 (rank : 295)
Query Neighborhood Hits	1031	Target Neighborhood Hits	263	Shared Neighborhood Hits	122
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SRRM2_HUMAN
NC score	0.135397 (rank : 337)	θ value	1.81305 (rank : 692)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1296	Shared Neighborhood Hits	334
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.133840 (rank : 338)	θ value	0.0961366 (rank : 425)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1470	Shared Neighborhood Hits	358
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MLL3_MOUSE
NC score	0.133504 (rank : 339)	θ value	0.00020696 (rank : 272)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1399	Shared Neighborhood Hits	357
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MBD6_HUMAN
NC score	0.131652 (rank : 340)	θ value	1.38821 (rank : 644)
Query Neighborhood Hits	1031	Target Neighborhood Hits	349	Shared Neighborhood Hits	162
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

SASH1_HUMAN
NC score	0.131243 (rank : 341)	θ value	0.0563607 (rank : 397)
Query Neighborhood Hits	1031	Target Neighborhood Hits	292	Shared Neighborhood Hits	161
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

TAF4_HUMAN
NC score	0.130546 (rank : 342)	θ value	2.36792 (rank : 733)
Query Neighborhood Hits	1031	Target Neighborhood Hits	687	Shared Neighborhood Hits	227
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ANKF1_HUMAN
NC score	0.128272 (rank : 343)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	1031	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

YLPM1_MOUSE
NC score	0.126801 (rank : 344)	θ value	0.21417 (rank : 481)
Query Neighborhood Hits	1031	Target Neighborhood Hits	505	Shared Neighborhood Hits	200
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

K1802_MOUSE
NC score	0.125845 (rank : 345)	θ value	3.77169e-06 (rank : 223)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1596	Shared Neighborhood Hits	389
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ALEX_HUMAN
NC score	0.125037 (rank : 346)	θ value	0.0148317 (rank : 350)
Query Neighborhood Hits	1031	Target Neighborhood Hits	361	Shared Neighborhood Hits	163
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

LRRK1_MOUSE
NC score	0.124891 (rank : 347)	θ value	0.0252991 (rank : 365)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1267	Shared Neighborhood Hits	190
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

YLPM1_HUMAN
NC score	0.124470 (rank : 348)	θ value	0.0736092 (rank : 414)
Query Neighborhood Hits	1031	Target Neighborhood Hits	670	Shared Neighborhood Hits	234
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

PRG4_MOUSE
NC score	0.123132 (rank : 349)	θ value	5.27518 (rank : 887)
Query Neighborhood Hits	1031	Target Neighborhood Hits	624	Shared Neighborhood Hits	196
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

GGN_MOUSE
NC score	0.123043 (rank : 350)	θ value	0.00869519 (rank : 336)
Query Neighborhood Hits	1031	Target Neighborhood Hits	311	Shared Neighborhood Hits	153
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MLL2_HUMAN
NC score	0.121331 (rank : 351)	θ value	8.99809 (rank : 999)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1788	Shared Neighborhood Hits	418
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RAPH1_HUMAN
NC score	0.121148 (rank : 352)	θ value	1.38821 (rank : 651)
Query Neighborhood Hits	1031	Target Neighborhood Hits	593	Shared Neighborhood Hits	257
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

FA47A_HUMAN
NC score	0.121022 (rank : 353)	θ value	0.00228821 (rank : 305)
Query Neighborhood Hits	1031	Target Neighborhood Hits	451	Shared Neighborhood Hits	185
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

CK024_HUMAN
NC score	0.119565 (rank : 354)	θ value	0.62314 (rank : 541)
Query Neighborhood Hits	1031	Target Neighborhood Hits	408	Shared Neighborhood Hits	184
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CBP_MOUSE
NC score	0.119411 (rank : 355)	θ value	0.0431538 (rank : 381)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1051	Shared Neighborhood Hits	347
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

LCP2_HUMAN
NC score	0.117879 (rank : 356)	θ value	0.0431538 (rank : 386)
Query Neighborhood Hits	1031	Target Neighborhood Hits	531	Shared Neighborhood Hits	219
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

FA47B_HUMAN
NC score	0.117867 (rank : 357)	θ value	0.00102713 (rank : 289)
Query Neighborhood Hits	1031	Target Neighborhood Hits	431	Shared Neighborhood Hits	185
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

TRPV4_HUMAN
NC score	0.116785 (rank : 358)	θ value	θ > 10 (rank : 1302)
Query Neighborhood Hits	1031	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CBP_HUMAN
NC score	0.115875 (rank : 359)	θ value	0.0330416 (rank : 367)
Query Neighborhood Hits	1031	Target Neighborhood Hits	941	Shared Neighborhood Hits	333
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

WASL_MOUSE
NC score	0.115451 (rank : 360)	θ value	0.125558 (rank : 446)
Query Neighborhood Hits	1031	Target Neighborhood Hits	339	Shared Neighborhood Hits	184
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RERE_MOUSE
NC score	0.114998 (rank : 361)	θ value	θ > 10 (rank : 1233)
Query Neighborhood Hits	1031	Target Neighborhood Hits	785	Shared Neighborhood Hits	276
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

CN155_HUMAN
NC score	0.114895 (rank : 362)	θ value	8.99809 (rank : 979)
Query Neighborhood Hits	1031	Target Neighborhood Hits	385	Shared Neighborhood Hits	140
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

SON_MOUSE
NC score	0.114865 (rank : 363)	θ value	1.06291 (rank : 623)
Query Neighborhood Hits	1031	Target Neighborhood Hits	957	Shared Neighborhood Hits	290
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CJ078_MOUSE
NC score	0.114634 (rank : 364)	θ value	0.62314 (rank : 540)
Query Neighborhood Hits	1031	Target Neighborhood Hits	559	Shared Neighborhood Hits	165
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

RTP3_MOUSE
NC score	0.114115 (rank : 365)	θ value	0.00035302 (rank : 279)
Query Neighborhood Hits	1031	Target Neighborhood Hits	374	Shared Neighborhood Hits	161
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

EPHB6_HUMAN
NC score	0.114098 (rank : 366)	θ value	0.0113563 (rank : 347)
Query Neighborhood Hits	1031	Target Neighborhood Hits	912	Shared Neighborhood Hits	121
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

PI5PA_HUMAN
NC score	0.113858 (rank : 367)	θ value	1.81305 (rank : 688)
Query Neighborhood Hits	1031	Target Neighborhood Hits	749	Shared Neighborhood Hits	314
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RERE_HUMAN
NC score	0.113468 (rank : 368)	θ value	θ > 10 (rank : 1232)
Query Neighborhood Hits	1031	Target Neighborhood Hits	779	Shared Neighborhood Hits	276
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

MISS_MOUSE
NC score	0.112904 (rank : 369)	θ value	0.813845 (rank : 585)
Query Neighborhood Hits	1031	Target Neighborhood Hits	444	Shared Neighborhood Hits	218
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

EPHB6_MOUSE
NC score	0.112832 (rank : 370)	θ value	0.00509761 (rank : 324)
Query Neighborhood Hits	1031	Target Neighborhood Hits	906	Shared Neighborhood Hits	109
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

WASL_HUMAN
NC score	0.112420 (rank : 371)	θ value	0.62314 (rank : 568)
Query Neighborhood Hits	1031	Target Neighborhood Hits	312	Shared Neighborhood Hits	168
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

EPHA5_HUMAN
NC score	0.112304 (rank : 372)	θ value	1.38499e-08 (rank : 167)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	119
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

SHAN2_MOUSE
NC score	0.112205 (rank : 373)	θ value	0.0736092 (rank : 409)
Query Neighborhood Hits	1031	Target Neighborhood Hits	446	Shared Neighborhood Hits	146
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

CIC_HUMAN
NC score	0.111342 (rank : 374)	θ value	0.00509761 (rank : 323)
Query Neighborhood Hits	1031	Target Neighborhood Hits	992	Shared Neighborhood Hits	365
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

RGS3_HUMAN
NC score	0.110678 (rank : 375)	θ value	4.92598e-06 (rank : 224)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1375	Shared Neighborhood Hits	373
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

EPHA6_HUMAN
NC score	0.110523 (rank : 376)	θ value	0.000786445 (rank : 285)
Query Neighborhood Hits	1031	Target Neighborhood Hits	959	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

NFH_MOUSE
NC score	0.110385 (rank : 377)	θ value	1.80886e-08 (rank : 170)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2247	Shared Neighborhood Hits	436
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

EPHA7_HUMAN
NC score	0.109903 (rank : 378)	θ value	2.61198e-07 (rank : 200)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1053	Shared Neighborhood Hits	115
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

CPSF6_MOUSE
NC score	0.109856 (rank : 379)	θ value	0.0431538 (rank : 385)
Query Neighborhood Hits	1031	Target Neighborhood Hits	356	Shared Neighborhood Hits	139
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

MLL4_HUMAN
NC score	0.109473 (rank : 380)	θ value	1.38821 (rank : 646)
Query Neighborhood Hits	1031	Target Neighborhood Hits	722	Shared Neighborhood Hits	249
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

EPHA1_MOUSE
NC score	0.109461 (rank : 381)	θ value	1.38499e-08 (rank : 166)
Query Neighborhood Hits	1031	Target Neighborhood Hits	958	Shared Neighborhood Hits	112
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA1_HUMAN
NC score	0.109314 (rank : 382)	θ value	2.36244e-08 (rank : 171)
Query Neighborhood Hits	1031	Target Neighborhood Hits	997	Shared Neighborhood Hits	119
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHB4_HUMAN
NC score	0.109108 (rank : 383)	θ value	1.87187e-05 (rank : 239)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1056	Shared Neighborhood Hits	121
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHAA_HUMAN
NC score	0.109085 (rank : 384)	θ value	0.00175202 (rank : 296)
Query Neighborhood Hits	1031	Target Neighborhood Hits	960	Shared Neighborhood Hits	107
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHA6_MOUSE
NC score	0.109016 (rank : 385)	θ value	0.00228821 (rank : 304)
Query Neighborhood Hits	1031	Target Neighborhood Hits	946	Shared Neighborhood Hits	99
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB3_HUMAN
NC score	0.108812 (rank : 386)	θ value	4.1701e-05 (rank : 250)
Query Neighborhood Hits	1031	Target Neighborhood Hits	996	Shared Neighborhood Hits	113
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHA7_MOUSE
NC score	0.108808 (rank : 387)	θ value	5.81887e-07 (rank : 209)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1025	Shared Neighborhood Hits	109
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

CN032_HUMAN
NC score	0.108756 (rank : 388)	θ value	5.27518 (rank : 865)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	128
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CPSF6_HUMAN
NC score	0.108745 (rank : 389)	θ value	0.0431538 (rank : 384)
Query Neighborhood Hits	1031	Target Neighborhood Hits	359	Shared Neighborhood Hits	137
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

SHAN2_HUMAN
NC score	0.108452 (rank : 390)	θ value	0.0736092 (rank : 408)
Query Neighborhood Hits	1031	Target Neighborhood Hits	346	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

EPHB2_HUMAN
NC score	0.108416 (rank : 391)	θ value	1.53129e-07 (rank : 194)
Query Neighborhood Hits	1031	Target Neighborhood Hits	983	Shared Neighborhood Hits	111
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

SF3A2_MOUSE
NC score	0.108252 (rank : 392)	θ value	1.06291 (rank : 622)
Query Neighborhood Hits	1031	Target Neighborhood Hits	247	Shared Neighborhood Hits	127
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

EP300_HUMAN
NC score	0.108246 (rank : 393)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	1031	Target Neighborhood Hits	821	Shared Neighborhood Hits	302
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EPHA2_HUMAN
NC score	0.108196 (rank : 394)	θ value	3.08544e-08 (rank : 175)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1021	Shared Neighborhood Hits	110
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

CS016_HUMAN
NC score	0.108180 (rank : 395)	θ value	2.36792 (rank : 702)
Query Neighborhood Hits	1031	Target Neighborhood Hits	310	Shared Neighborhood Hits	152
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

EPHA2_MOUSE
NC score	0.108158 (rank : 396)	θ value	8.97725e-08 (rank : 186)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1020	Shared Neighborhood Hits	111
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

SET1A_HUMAN
NC score	0.107735 (rank : 397)	θ value	θ > 10 (rank : 1257)
Query Neighborhood Hits	1031	Target Neighborhood Hits	690	Shared Neighborhood Hits	209
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

EPHB4_MOUSE
NC score	0.107723 (rank : 398)	θ value	1.87187e-05 (rank : 240)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1013	Shared Neighborhood Hits	118
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHB3_MOUSE
NC score	0.107562 (rank : 399)	θ value	4.1701e-05 (rank : 251)
Query Neighborhood Hits	1031	Target Neighborhood Hits	996	Shared Neighborhood Hits	107
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

TXND2_HUMAN
NC score	0.107537 (rank : 400)	θ value	3.19293e-05 (rank : 248)
Query Neighborhood Hits	1031	Target Neighborhood Hits	793	Shared Neighborhood Hits	194
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

BASP_MOUSE
NC score	0.107483 (rank : 401)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	94
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

ENAH_MOUSE
NC score	0.107393 (rank : 402)	θ value	2.36792 (rank : 707)
Query Neighborhood Hits	1031	Target Neighborhood Hits	919	Shared Neighborhood Hits	258
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

TRPV4_MOUSE
NC score	0.107375 (rank : 403)	θ value	θ > 10 (rank : 1303)
Query Neighborhood Hits	1031	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

EPHA8_MOUSE
NC score	0.107003 (rank : 404)	θ value	0.000786445 (rank : 286)
Query Neighborhood Hits	1031	Target Neighborhood Hits	969	Shared Neighborhood Hits	104
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

GGN_HUMAN
NC score	0.106983 (rank : 405)	θ value	5.27518 (rank : 874)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	140
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

EPHB2_MOUSE
NC score	0.106768 (rank : 406)	θ value	8.40245e-06 (rank : 230)
Query Neighborhood Hits	1031	Target Neighborhood Hits	982	Shared Neighborhood Hits	111
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

PRR8_HUMAN
NC score	0.106744 (rank : 407)	θ value	0.00665767 (rank : 332)
Query Neighborhood Hits	1031	Target Neighborhood Hits	217	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

CN032_MOUSE
NC score	0.106669 (rank : 408)	θ value	3.0926 (rank : 746)
Query Neighborhood Hits	1031	Target Neighborhood Hits	233	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

EPHB1_HUMAN
NC score	0.105600 (rank : 409)	θ value	1.87187e-05 (rank : 238)
Query Neighborhood Hits	1031	Target Neighborhood Hits	988	Shared Neighborhood Hits	112
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

CS007_MOUSE
NC score	0.105415 (rank : 410)	θ value	0.00869519 (rank : 335)
Query Neighborhood Hits	1031	Target Neighborhood Hits	464	Shared Neighborhood Hits	175
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

EPHA8_HUMAN
NC score	0.104998 (rank : 411)	θ value	0.00134147 (rank : 291)
Query Neighborhood Hits	1031	Target Neighborhood Hits	956	Shared Neighborhood Hits	103
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

ARI1A_HUMAN
NC score	0.104907 (rank : 412)	θ value	0.125558 (rank : 432)
Query Neighborhood Hits	1031	Target Neighborhood Hits	787	Shared Neighborhood Hits	271
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

SC24C_HUMAN
NC score	0.104491 (rank : 413)	θ value	0.000121331 (rank : 265)
Query Neighborhood Hits	1031	Target Neighborhood Hits	662	Shared Neighborhood Hits	266
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SYN1_HUMAN
NC score	0.103946 (rank : 414)	θ value	1.38821 (rank : 657)
Query Neighborhood Hits	1031	Target Neighborhood Hits	419	Shared Neighborhood Hits	202
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

EPHA4_MOUSE
NC score	0.103909 (rank : 415)	θ value	0.000121331 (rank : 262)
Query Neighborhood Hits	1031	Target Neighborhood Hits	982	Shared Neighborhood Hits	106
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

WASF2_MOUSE
NC score	0.103847 (rank : 416)	θ value	2.36792 (rank : 737)
Query Neighborhood Hits	1031	Target Neighborhood Hits	315	Shared Neighborhood Hits	178
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

BCAR1_HUMAN
NC score	0.103717 (rank : 417)	θ value	0.0193708 (rank : 357)
Query Neighborhood Hits	1031	Target Neighborhood Hits	554	Shared Neighborhood Hits	231
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

EPHA4_HUMAN
NC score	0.103615 (rank : 418)	θ value	0.00020696 (rank : 270)
Query Neighborhood Hits	1031	Target Neighborhood Hits	975	Shared Neighborhood Hits	106
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

K1543_MOUSE
NC score	0.103568 (rank : 419)	θ value	0.279714 (rank : 488)
Query Neighborhood Hits	1031	Target Neighborhood Hits	497	Shared Neighborhood Hits	196
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LRRK1_HUMAN
NC score	0.103013 (rank : 420)	θ value	0.00390308 (rank : 315)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1237	Shared Neighborhood Hits	163
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

SF3A2_HUMAN
NC score	0.102985 (rank : 421)	θ value	6.88961 (rank : 960)
Query Neighborhood Hits	1031	Target Neighborhood Hits	263	Shared Neighborhood Hits	130
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

WASP_MOUSE
NC score	0.102684 (rank : 422)	θ value	0.163984 (rank : 463)
Query Neighborhood Hits	1031	Target Neighborhood Hits	223	Shared Neighborhood Hits	113
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

TRPC6_HUMAN
NC score	0.102094 (rank : 423)	θ value	θ > 10 (rank : 1297)
Query Neighborhood Hits	1031	Target Neighborhood Hits	171	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

BAG3_MOUSE
NC score	0.102027 (rank : 424)	θ value	0.47712 (rank : 519)
Query Neighborhood Hits	1031	Target Neighborhood Hits	513	Shared Neighborhood Hits	232
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

MUCDL_HUMAN
NC score	0.101858 (rank : 425)	θ value	θ > 10 (rank : 1207)
Query Neighborhood Hits	1031	Target Neighborhood Hits	777	Shared Neighborhood Hits	282
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

EPHA5_MOUSE
NC score	0.101831 (rank : 426)	θ value	5.81887e-07 (rank : 208)
Query Neighborhood Hits	1031	Target Neighborhood Hits	950	Shared Neighborhood Hits	105
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

PRR13_HUMAN
NC score	0.100746 (rank : 427)	θ value	0.813845 (rank : 590)
Query Neighborhood Hits	1031	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

FMNL_HUMAN
NC score	0.100736 (rank : 428)	θ value	0.00509761 (rank : 325)
Query Neighborhood Hits	1031	Target Neighborhood Hits	529	Shared Neighborhood Hits	188
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

SFPQ_MOUSE
NC score	0.100702 (rank : 429)	θ value	0.0563607 (rank : 398)
Query Neighborhood Hits	1031	Target Neighborhood Hits	958	Shared Neighborhood Hits	247
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

PRP5_HUMAN
NC score	0.100309 (rank : 430)	θ value	1.38821 (rank : 649)
Query Neighborhood Hits	1031	Target Neighborhood Hits	108	Shared Neighborhood Hits	54
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

WASF1_MOUSE
NC score	0.099914 (rank : 431)	θ value	0.279714 (rank : 496)
Query Neighborhood Hits	1031	Target Neighborhood Hits	261	Shared Neighborhood Hits	150
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

CEL_HUMAN
NC score	0.099172 (rank : 432)	θ value	0.00869519 (rank : 334)
Query Neighborhood Hits	1031	Target Neighborhood Hits	896	Shared Neighborhood Hits	325
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CEND3_HUMAN
NC score	0.099085 (rank : 433)	θ value	0.125558 (rank : 435)
Query Neighborhood Hits	1031	Target Neighborhood Hits	275	Shared Neighborhood Hits	117
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

S23IP_MOUSE
NC score	0.098346 (rank : 434)	θ value	0.125558 (rank : 444)
Query Neighborhood Hits	1031	Target Neighborhood Hits	363	Shared Neighborhood Hits	165
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

MUC2_HUMAN
NC score	0.097463 (rank : 435)	θ value	3.0926 (rank : 777)
Query Neighborhood Hits	1031	Target Neighborhood Hits	906	Shared Neighborhood Hits	244
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

WASF1_HUMAN
NC score	0.097308 (rank : 436)	θ value	0.279714 (rank : 495)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	148
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

FMN2_HUMAN
NC score	0.096850 (rank : 437)	θ value	0.0563607 (rank : 393)
Query Neighborhood Hits	1031	Target Neighborhood Hits	484	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

FYB_HUMAN
NC score	0.096355 (rank : 438)	θ value	0.0563607 (rank : 394)
Query Neighborhood Hits	1031	Target Neighborhood Hits	379	Shared Neighborhood Hits	146
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

SYN1_MOUSE
NC score	0.096201 (rank : 439)	θ value	0.279714 (rank : 494)
Query Neighborhood Hits	1031	Target Neighborhood Hits	363	Shared Neighborhood Hits	175
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TCGAP_HUMAN
NC score	0.095837 (rank : 440)	θ value	θ > 10 (rank : 1276)
Query Neighborhood Hits	1031	Target Neighborhood Hits	872	Shared Neighborhood Hits	327
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SARM1_MOUSE
NC score	0.095731 (rank : 441)	θ value	0.00134147 (rank : 294)
Query Neighborhood Hits	1031	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

CEND3_MOUSE
NC score	0.095244 (rank : 442)	θ value	0.0431538 (rank : 383)
Query Neighborhood Hits	1031	Target Neighborhood Hits	228	Shared Neighborhood Hits	96
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

EPHA3_HUMAN
NC score	0.095165 (rank : 443)	θ value	0.0330416 (rank : 372)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1005	Shared Neighborhood Hits	99
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA3_MOUSE
NC score	0.095046 (rank : 444)	θ value	0.0736092 (rank : 405)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	97
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

TARA_HUMAN
NC score	0.094289 (rank : 445)	θ value	θ > 10 (rank : 1274)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1626	Shared Neighborhood Hits	349
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SAPS1_HUMAN
NC score	0.094272 (rank : 446)	θ value	0.0148317 (rank : 355)
Query Neighborhood Hits	1031	Target Neighborhood Hits	704	Shared Neighborhood Hits	275
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SFPQ_HUMAN
NC score	0.094088 (rank : 447)	θ value	0.47712 (rank : 532)
Query Neighborhood Hits	1031	Target Neighborhood Hits	986	Shared Neighborhood Hits	256
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

PELP1_MOUSE
NC score	0.094070 (rank : 448)	θ value	0.813845 (rank : 589)
Query Neighborhood Hits	1031	Target Neighborhood Hits	709	Shared Neighborhood Hits	233
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

MINT_MOUSE
NC score	0.093569 (rank : 449)	θ value	3.0926 (rank : 774)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1514	Shared Neighborhood Hits	374
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NU214_HUMAN
NC score	0.093483 (rank : 450)	θ value	0.813845 (rank : 587)
Query Neighborhood Hits	1031	Target Neighborhood Hits	657	Shared Neighborhood Hits	175
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PRR13_MOUSE
NC score	0.093187 (rank : 451)	θ value	0.21417 (rank : 472)
Query Neighborhood Hits	1031	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

CD2_HUMAN
NC score	0.092840 (rank : 452)	θ value	0.813845 (rank : 574)
Query Neighborhood Hits	1031	Target Neighborhood Hits	504	Shared Neighborhood Hits	211
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

BASP_HUMAN
NC score	0.092759 (rank : 453)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	1031	Target Neighborhood Hits	321	Shared Neighborhood Hits	100
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CABIN_HUMAN
NC score	0.091936 (rank : 454)	θ value	2.36792 (rank : 700)
Query Neighborhood Hits	1031	Target Neighborhood Hits	490	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

SSBP4_HUMAN
NC score	0.091350 (rank : 455)	θ value	0.21417 (rank : 476)
Query Neighborhood Hits	1031	Target Neighborhood Hits	753	Shared Neighborhood Hits	288
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SPR1B_MOUSE
NC score	0.091326 (rank : 456)	θ value	0.0961366 (rank : 423)
Query Neighborhood Hits	1031	Target Neighborhood Hits	395	Shared Neighborhood Hits	180
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

K1802_HUMAN
NC score	0.091311 (rank : 457)	θ value	0.125558 (rank : 441)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1378	Shared Neighborhood Hits	337
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MILK1_MOUSE
NC score	0.091029 (rank : 458)	θ value	0.21417 (rank : 469)
Query Neighborhood Hits	1031	Target Neighborhood Hits	788	Shared Neighborhood Hits	292
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

BCAR1_MOUSE
NC score	0.090501 (rank : 459)	θ value	0.0961366 (rank : 417)
Query Neighborhood Hits	1031	Target Neighborhood Hits	438	Shared Neighborhood Hits	193
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

LARP4_MOUSE
NC score	0.089728 (rank : 460)	θ value	0.000270298 (rank : 274)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

GRIN1_HUMAN
NC score	0.089341 (rank : 461)	θ value	6.88961 (rank : 936)
Query Neighborhood Hits	1031	Target Neighborhood Hits	681	Shared Neighborhood Hits	218
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

CO039_MOUSE
NC score	0.088972 (rank : 462)	θ value	0.365318 (rank : 500)
Query Neighborhood Hits	1031	Target Neighborhood Hits	445	Shared Neighborhood Hits	210
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

SLY_MOUSE
NC score	0.088769 (rank : 463)	θ value	0.0563607 (rank : 400)
Query Neighborhood Hits	1031	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

CU081_HUMAN
NC score	0.088623 (rank : 464)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	1031	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DIDO1_HUMAN
NC score	0.088561 (rank : 465)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	1031	Target Neighborhood Hits	960	Shared Neighborhood Hits	257
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SAMN1_HUMAN
NC score	0.088368 (rank : 466)	θ value	0.125558 (rank : 445)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

DGKD_HUMAN
NC score	0.088311 (rank : 467)	θ value	0.0252991 (rank : 364)
Query Neighborhood Hits	1031	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

WASF2_HUMAN
NC score	0.088228 (rank : 468)	θ value	6.88961 (rank : 968)
Query Neighborhood Hits	1031	Target Neighborhood Hits	280	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

ZN207_HUMAN
NC score	0.088145 (rank : 469)	θ value	θ > 10 (rank : 1319)
Query Neighborhood Hits	1031	Target Neighborhood Hits	326	Shared Neighborhood Hits	104
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

SAMN1_MOUSE
NC score	0.088144 (rank : 470)	θ value	0.0961366 (rank : 422)
Query Neighborhood Hits	1031	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

CIC_MOUSE
NC score	0.087941 (rank : 471)	θ value	4.03905 (rank : 813)
Query Neighborhood Hits	1031	Target Neighborhood Hits	742	Shared Neighborhood Hits	270
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

K1543_HUMAN
NC score	0.087344 (rank : 472)	θ value	0.813845 (rank : 583)
Query Neighborhood Hits	1031	Target Neighborhood Hits	435	Shared Neighborhood Hits	183
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PRPE_HUMAN
NC score	0.087322 (rank : 473)	θ value	1.81305 (rank : 689)
Query Neighborhood Hits	1031	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

ZN385_HUMAN
NC score	0.087202 (rank : 474)	θ value	0.0736092 (rank : 416)
Query Neighborhood Hits	1031	Target Neighborhood Hits	614	Shared Neighborhood Hits	205
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

WASP_HUMAN
NC score	0.087101 (rank : 475)	θ value	0.21417 (rank : 480)
Query Neighborhood Hits	1031	Target Neighborhood Hits	195	Shared Neighborhood Hits	115
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

SYNJ1_HUMAN
NC score	0.086970 (rank : 476)	θ value	0.0563607 (rank : 401)
Query Neighborhood Hits	1031	Target Neighborhood Hits	498	Shared Neighborhood Hits	219
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

LAD1_MOUSE
NC score	0.086912 (rank : 477)	θ value	θ > 10 (rank : 1165)
Query Neighborhood Hits	1031	Target Neighborhood Hits	391	Shared Neighborhood Hits	116
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

CCNK_MOUSE
NC score	0.086909 (rank : 478)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	159
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

NOLC1_HUMAN
NC score	0.086490 (rank : 479)	θ value	θ > 10 (rank : 1211)
Query Neighborhood Hits	1031	Target Neighborhood Hits	452	Shared Neighborhood Hits	117
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

BRD4_MOUSE
NC score	0.086433 (rank : 480)	θ value	1.38821 (rank : 630)
Query Neighborhood Hits	1031	Target Neighborhood Hits	845	Shared Neighborhood Hits	235
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

WASF4_HUMAN
NC score	0.086169 (rank : 481)	θ value	θ > 10 (rank : 1311)
Query Neighborhood Hits	1031	Target Neighborhood Hits	282	Shared Neighborhood Hits	152
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

TGON2_HUMAN
NC score	0.086060 (rank : 482)	θ value	θ > 10 (rank : 1285)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1037	Shared Neighborhood Hits	228
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CS007_HUMAN
NC score	0.086007 (rank : 483)	θ value	0.0330416 (rank : 370)
Query Neighborhood Hits	1031	Target Neighborhood Hits	401	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CECR2_HUMAN
NC score	0.085989 (rank : 484)	θ value	0.0431538 (rank : 382)
Query Neighborhood Hits	1031	Target Neighborhood Hits	543	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

PCQAP_HUMAN
NC score	0.085838 (rank : 485)	θ value	θ > 10 (rank : 1218)
Query Neighborhood Hits	1031	Target Neighborhood Hits	549	Shared Neighborhood Hits	167
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

TRPC3_HUMAN
NC score	0.085806 (rank : 486)	θ value	6.88961 (rank : 966)
Query Neighborhood Hits	1031	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

SLY_HUMAN
NC score	0.085503 (rank : 487)	θ value	0.0563607 (rank : 399)
Query Neighborhood Hits	1031	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

BAT3_MOUSE
NC score	0.085097 (rank : 488)	θ value	4.03905 (rank : 806)
Query Neighborhood Hits	1031	Target Neighborhood Hits	518	Shared Neighborhood Hits	211
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

SNPC4_HUMAN
NC score	0.085092 (rank : 489)	θ value	θ > 10 (rank : 1266)
Query Neighborhood Hits	1031	Target Neighborhood Hits	589	Shared Neighborhood Hits	241
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

PSL1_HUMAN
NC score	0.084943 (rank : 490)	θ value	0.365318 (rank : 506)
Query Neighborhood Hits	1031	Target Neighborhood Hits	650	Shared Neighborhood Hits	265
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

MKL1_MOUSE
NC score	0.084893 (rank : 491)	θ value	0.0113563 (rank : 348)
Query Neighborhood Hits	1031	Target Neighborhood Hits	667	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

HRX_HUMAN
NC score	0.084840 (rank : 492)	θ value	0.0330416 (rank : 374)
Query Neighborhood Hits	1031	Target Neighborhood Hits	825	Shared Neighborhood Hits	199
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TCOF_MOUSE
NC score	0.084797 (rank : 493)	θ value	θ > 10 (rank : 1278)
Query Neighborhood Hits	1031	Target Neighborhood Hits	471	Shared Neighborhood Hits	145
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

DGKK_HUMAN
NC score	0.084773 (rank : 494)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	1031	Target Neighborhood Hits	378	Shared Neighborhood Hits	145
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

SELPL_MOUSE
NC score	0.084192 (rank : 495)	θ value	θ > 10 (rank : 1255)
Query Neighborhood Hits	1031	Target Neighborhood Hits	588	Shared Neighborhood Hits	212
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CDN1C_HUMAN
NC score	0.084104 (rank : 496)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	1031	Target Neighborhood Hits	168	Shared Neighborhood Hits	94
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

MUC13_MOUSE
NC score	0.083581 (rank : 497)	θ value	θ > 10 (rank : 1205)
Query Neighborhood Hits	1031	Target Neighborhood Hits	447	Shared Neighborhood Hits	110
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ATX2L_HUMAN
NC score	0.083176 (rank : 498)	θ value	2.36792 (rank : 699)
Query Neighborhood Hits	1031	Target Neighborhood Hits	443	Shared Neighborhood Hits	171
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

MARCS_HUMAN
NC score	0.083156 (rank : 499)	θ value	θ > 10 (rank : 1188)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	78
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

CRTC1_HUMAN
NC score	0.083132 (rank : 500)	θ value	1.81305 (rank : 669)
Query Neighborhood Hits	1031	Target Neighborhood Hits	319	Shared Neighborhood Hits	167
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

SMR3A_HUMAN
NC score	0.082903 (rank : 501)	θ value	4.03905 (rank : 847)
Query Neighborhood Hits	1031	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

WASF3_MOUSE
NC score	0.082842 (rank : 502)	θ value	0.00869519 (rank : 339)
Query Neighborhood Hits	1031	Target Neighborhood Hits	188	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

OGFR_MOUSE
NC score	0.082780 (rank : 503)	θ value	θ > 10 (rank : 1217)
Query Neighborhood Hits	1031	Target Neighborhood Hits	584	Shared Neighborhood Hits	161
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

MEGF9_MOUSE
NC score	0.082662 (rank : 504)	θ value	0.0431538 (rank : 387)
Query Neighborhood Hits	1031	Target Neighborhood Hits	896	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SYNJ1_MOUSE
NC score	0.082179 (rank : 505)	θ value	0.813845 (rank : 594)
Query Neighborhood Hits	1031	Target Neighborhood Hits	516	Shared Neighborhood Hits	227
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

IWS1_MOUSE
NC score	0.082041 (rank : 506)	θ value	1.06291 (rank : 611)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1258	Shared Neighborhood Hits	235
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TROAP_HUMAN
NC score	0.081979 (rank : 507)	θ value	4.03905 (rank : 853)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	119
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

CD248_HUMAN
NC score	0.081805 (rank : 508)	θ value	0.0252991 (rank : 361)
Query Neighborhood Hits	1031	Target Neighborhood Hits	679	Shared Neighborhood Hits	211
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MUC1_MOUSE
NC score	0.081020 (rank : 509)	θ value	θ > 10 (rank : 1206)
Query Neighborhood Hits	1031	Target Neighborhood Hits	388	Shared Neighborhood Hits	96
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SARM1_HUMAN
NC score	0.080565 (rank : 510)	θ value	1.06291 (rank : 621)
Query Neighborhood Hits	1031	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

K1683_HUMAN
NC score	0.080448 (rank : 511)	θ value	0.0563607 (rank : 395)
Query Neighborhood Hits	1031	Target Neighborhood Hits	240	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SPR1A_MOUSE
NC score	0.079973 (rank : 512)	θ value	0.813845 (rank : 592)
Query Neighborhood Hits	1031	Target Neighborhood Hits	343	Shared Neighborhood Hits	168
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

WASF3_HUMAN
NC score	0.079613 (rank : 513)	θ value	0.365318 (rank : 514)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

ARI1B_HUMAN
NC score	0.079589 (rank : 514)	θ value	3.0926 (rank : 742)
Query Neighborhood Hits	1031	Target Neighborhood Hits	567	Shared Neighborhood Hits	214
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

PELP1_HUMAN
NC score	0.079386 (rank : 515)	θ value	5.27518 (rank : 884)
Query Neighborhood Hits	1031	Target Neighborhood Hits	596	Shared Neighborhood Hits	157
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

BAT3_HUMAN
NC score	0.079141 (rank : 516)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	1031	Target Neighborhood Hits	490	Shared Neighborhood Hits	204
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

TM108_MOUSE
NC score	0.078967 (rank : 517)	θ value	θ > 10 (rank : 1290)
Query Neighborhood Hits	1031	Target Neighborhood Hits	336	Shared Neighborhood Hits	145
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

NCOR2_HUMAN
NC score	0.078404 (rank : 518)	θ value	8.99809 (rank : 1002)
Query Neighborhood Hits	1031	Target Neighborhood Hits	870	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

FMN2_MOUSE
NC score	0.078202 (rank : 519)	θ value	3.0926 (rank : 758)
Query Neighborhood Hits	1031	Target Neighborhood Hits	349	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MNT_HUMAN
NC score	0.078179 (rank : 520)	θ value	3.0926 (rank : 776)
Query Neighborhood Hits	1031	Target Neighborhood Hits	496	Shared Neighborhood Hits	191
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

FMN1A_MOUSE
NC score	0.078167 (rank : 521)	θ value	4.03905 (rank : 822)
Query Neighborhood Hits	1031	Target Neighborhood Hits	423	Shared Neighborhood Hits	167
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

CTDP1_HUMAN
NC score	0.078116 (rank : 522)	θ value	1.38821 (rank : 634)
Query Neighborhood Hits	1031	Target Neighborhood Hits	416	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

PRPC_HUMAN
NC score	0.078099 (rank : 523)	θ value	1.06291 (rank : 619)
Query Neighborhood Hits	1031	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

K0310_HUMAN
NC score	0.078063 (rank : 524)	θ value	4.03905 (rank : 832)
Query Neighborhood Hits	1031	Target Neighborhood Hits	420	Shared Neighborhood Hits	174
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

TAU_MOUSE
NC score	0.078049 (rank : 525)	θ value	0.813845 (rank : 595)
Query Neighborhood Hits	1031	Target Neighborhood Hits	502	Shared Neighborhood Hits	188
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

SFR15_HUMAN
NC score	0.077864 (rank : 526)	θ value	5.27518 (rank : 891)
Query Neighborhood Hits	1031	Target Neighborhood Hits	368	Shared Neighborhood Hits	127
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

TAU_HUMAN
NC score	0.077297 (rank : 527)	θ value	θ > 10 (rank : 1275)
Query Neighborhood Hits	1031	Target Neighborhood Hits	448	Shared Neighborhood Hits	186
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PI5PA_MOUSE
NC score	0.077291 (rank : 528)	θ value	6.88961 (rank : 949)
Query Neighborhood Hits	1031	Target Neighborhood Hits	331	Shared Neighborhood Hits	165
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PHLB1_HUMAN
NC score	0.077007 (rank : 529)	θ value	0.0330416 (rank : 376)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1038	Shared Neighborhood Hits	225
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MBB1A_HUMAN
NC score	0.076960 (rank : 530)	θ value	0.62314 (rank : 551)
Query Neighborhood Hits	1031	Target Neighborhood Hits	665	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

ZIMP7_MOUSE
NC score	0.076102 (rank : 531)	θ value	0.62314 (rank : 569)
Query Neighborhood Hits	1031	Target Neighborhood Hits	566	Shared Neighborhood Hits	232
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

MARCS_MOUSE
NC score	0.075934 (rank : 532)	θ value	θ > 10 (rank : 1189)
Query Neighborhood Hits	1031	Target Neighborhood Hits	227	Shared Neighborhood Hits	78
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

TRPC3_MOUSE
NC score	0.075923 (rank : 533)	θ value	θ > 10 (rank : 1296)
Query Neighborhood Hits	1031	Target Neighborhood Hits	131	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

AFF1_HUMAN
NC score	0.075830 (rank : 534)	θ value	6.88961 (rank : 911)
Query Neighborhood Hits	1031	Target Neighborhood Hits	506	Shared Neighborhood Hits	145
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ATX2_MOUSE
NC score	0.075808 (rank : 535)	θ value	0.62314 (rank : 537)
Query Neighborhood Hits	1031	Target Neighborhood Hits	445	Shared Neighborhood Hits	173
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

WNK2_HUMAN
NC score	0.075402 (rank : 536)	θ value	0.163984 (rank : 464)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1407	Shared Neighborhood Hits	325
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

TRPC6_MOUSE
NC score	0.075196 (rank : 537)	θ value	θ > 10 (rank : 1298)
Query Neighborhood Hits	1031	Target Neighborhood Hits	171	Shared Neighborhood Hits	97
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

CEND1_HUMAN
NC score	0.075185 (rank : 538)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

SPTA3_MOUSE
NC score	0.075075 (rank : 539)	θ value	0.0961366 (rank : 424)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D9T6, Q80ZS4, Q9D5L5, Q9DAF5	Gene names	Spata3, Tsarg1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1) (mTSARG1).

MINT_HUMAN
NC score	0.074985 (rank : 540)	θ value	1.38821 (rank : 645)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1291	Shared Neighborhood Hits	280
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MTSS1_MOUSE
NC score	0.074930 (rank : 541)	θ value	6.88961 (rank : 944)
Query Neighborhood Hits	1031	Target Neighborhood Hits	592	Shared Neighborhood Hits	221
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

GRIN1_MOUSE
NC score	0.074879 (rank : 542)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	1031	Target Neighborhood Hits	337	Shared Neighborhood Hits	135
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HRBL_MOUSE
NC score	0.074475 (rank : 543)	θ value	0.00175202 (rank : 297)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	99
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

MAP1A_HUMAN
NC score	0.074402 (rank : 544)	θ value	1.81305 (rank : 681)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1626	Shared Neighborhood Hits	319
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

FMN1B_MOUSE
NC score	0.074358 (rank : 545)	θ value	4.03905 (rank : 823)
Query Neighborhood Hits	1031	Target Neighborhood Hits	447	Shared Neighborhood Hits	162
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

CIZ1_HUMAN
NC score	0.074258 (rank : 546)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	1031	Target Neighborhood Hits	359	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

ACK1_HUMAN
NC score	0.074251 (rank : 547)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1140	Shared Neighborhood Hits	261
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

SPT5H_MOUSE
NC score	0.074007 (rank : 548)	θ value	3.0926 (rank : 789)
Query Neighborhood Hits	1031	Target Neighborhood Hits	437	Shared Neighborhood Hits	182
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.073983 (rank : 549)	θ value	3.0926 (rank : 788)
Query Neighborhood Hits	1031	Target Neighborhood Hits	436	Shared Neighborhood Hits	181
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

MUC5B_HUMAN
NC score	0.073977 (rank : 550)	θ value	3.0926 (rank : 778)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1020	Shared Neighborhood Hits	208
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

GA2L2_MOUSE
NC score	0.073706 (rank : 551)	θ value	0.0736092 (rank : 406)
Query Neighborhood Hits	1031	Target Neighborhood Hits	395	Shared Neighborhood Hits	168
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

ACK1_MOUSE
NC score	0.073687 (rank : 552)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1080	Shared Neighborhood Hits	237
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

RPB1_HUMAN
NC score	0.073686 (rank : 553)	θ value	2.36792 (rank : 730)
Query Neighborhood Hits	1031	Target Neighborhood Hits	362	Shared Neighborhood Hits	132
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
NC score	0.073662 (rank : 554)	θ value	2.36792 (rank : 731)
Query Neighborhood Hits	1031	Target Neighborhood Hits	363	Shared Neighborhood Hits	133
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

BRD4_HUMAN
NC score	0.073472 (rank : 555)	θ value	1.81305 (rank : 666)
Query Neighborhood Hits	1031	Target Neighborhood Hits	851	Shared Neighborhood Hits	231
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

TCOF_HUMAN
NC score	0.073204 (rank : 556)	θ value	θ > 10 (rank : 1277)
Query Neighborhood Hits	1031	Target Neighborhood Hits	543	Shared Neighborhood Hits	137
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ALEX_MOUSE
NC score	0.073197 (rank : 557)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	1031	Target Neighborhood Hits	197	Shared Neighborhood Hits	95
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

MADCA_HUMAN
NC score	0.073018 (rank : 558)	θ value	θ > 10 (rank : 1184)
Query Neighborhood Hits	1031	Target Neighborhood Hits	221	Shared Neighborhood Hits	104
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

PO121_HUMAN
NC score	0.072966 (rank : 559)	θ value	θ > 10 (rank : 1222)
Query Neighborhood Hits	1031	Target Neighborhood Hits	344	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

DGKH_HUMAN
NC score	0.072887 (rank : 560)	θ value	0.0330416 (rank : 371)
Query Neighborhood Hits	1031	Target Neighborhood Hits	255	Shared Neighborhood Hits	65
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

3BP1_HUMAN
NC score	0.072858 (rank : 561)	θ value	0.0113563 (rank : 340)
Query Neighborhood Hits	1031	Target Neighborhood Hits	376	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

T22D2_HUMAN
NC score	0.072736 (rank : 562)	θ value	θ > 10 (rank : 1271)
Query Neighborhood Hits	1031	Target Neighborhood Hits	250	Shared Neighborhood Hits	114
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

DIAP1_MOUSE
NC score	0.072527 (rank : 563)	θ value	1.06291 (rank : 607)
Query Neighborhood Hits	1031	Target Neighborhood Hits	839	Shared Neighborhood Hits	175
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

IF4G1_MOUSE
NC score	0.072501 (rank : 564)	θ value	0.00665767 (rank : 331)
Query Neighborhood Hits	1031	Target Neighborhood Hits	534	Shared Neighborhood Hits	197
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

MAP4_HUMAN
NC score	0.072160 (rank : 565)	θ value	θ > 10 (rank : 1186)
Query Neighborhood Hits	1031	Target Neighborhood Hits	428	Shared Neighborhood Hits	148
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SELV_HUMAN
NC score	0.072097 (rank : 566)	θ value	θ > 10 (rank : 1256)
Query Neighborhood Hits	1031	Target Neighborhood Hits	118	Shared Neighborhood Hits	70
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

M3K11_HUMAN
NC score	0.071995 (rank : 567)	θ value	1.06291 (rank : 612)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1136	Shared Neighborhood Hits	196
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

SGIP1_MOUSE
NC score	0.071795 (rank : 568)	θ value	8.99809 (rank : 1015)
Query Neighborhood Hits	1031	Target Neighborhood Hits	180	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CSF1_HUMAN
NC score	0.071772 (rank : 569)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	116
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

TULP4_HUMAN
NC score	0.071725 (rank : 570)	θ value	0.0330416 (rank : 380)
Query Neighborhood Hits	1031	Target Neighborhood Hits	426	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

DIAP1_HUMAN
NC score	0.071534 (rank : 571)	θ value	5.27518 (rank : 869)
Query Neighborhood Hits	1031	Target Neighborhood Hits	784	Shared Neighborhood Hits	178
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

TRPC7_HUMAN
NC score	0.071500 (rank : 572)	θ value	θ > 10 (rank : 1299)
Query Neighborhood Hits	1031	Target Neighborhood Hits	123	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

NUMBL_HUMAN
NC score	0.071375 (rank : 573)	θ value	0.813845 (rank : 588)
Query Neighborhood Hits	1031	Target Neighborhood Hits	394	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

RP1L1_HUMAN
NC score	0.071310 (rank : 574)	θ value	4.03905 (rank : 842)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1072	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RIPK2_HUMAN
NC score	0.071305 (rank : 575)	θ value	θ > 10 (rank : 1238)
Query Neighborhood Hits	1031	Target Neighborhood Hits	774	Shared Neighborhood Hits	77
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

TRPC5_MOUSE
NC score	0.071119 (rank : 576)	θ value	0.0961366 (rank : 427)
Query Neighborhood Hits	1031	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

SREC2_HUMAN
NC score	0.071063 (rank : 577)	θ value	0.0113563 (rank : 349)
Query Neighborhood Hits	1031	Target Neighborhood Hits	645	Shared Neighborhood Hits	128
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

PO121_MOUSE
NC score	0.070847 (rank : 578)	θ value	θ > 10 (rank : 1223)
Query Neighborhood Hits	1031	Target Neighborhood Hits	345	Shared Neighborhood Hits	123
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

TB182_HUMAN
NC score	0.070679 (rank : 579)	θ value	6.88961 (rank : 964)
Query Neighborhood Hits	1031	Target Neighborhood Hits	414	Shared Neighborhood Hits	124
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

WBS14_HUMAN
NC score	0.070395 (rank : 580)	θ value	3.0926 (rank : 797)
Query Neighborhood Hits	1031	Target Neighborhood Hits	273	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

TRPC7_MOUSE
NC score	0.070348 (rank : 581)	θ value	θ > 10 (rank : 1300)
Query Neighborhood Hits	1031	Target Neighborhood Hits	114	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

ATX2L_MOUSE
NC score	0.070261 (rank : 582)	θ value	1.81305 (rank : 664)
Query Neighborhood Hits	1031	Target Neighborhood Hits	401	Shared Neighborhood Hits	157
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

BAG3_HUMAN
NC score	0.070164 (rank : 583)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	1031	Target Neighborhood Hits	314	Shared Neighborhood Hits	140
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CEND1_MOUSE
NC score	0.069681 (rank : 584)	θ value	5.27518 (rank : 861)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

TRPC5_HUMAN
NC score	0.069647 (rank : 585)	θ value	0.0961366 (rank : 426)
Query Neighborhood Hits	1031	Target Neighborhood Hits	122	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

AUTS2_HUMAN
NC score	0.069641 (rank : 586)	θ value	1.81305 (rank : 665)
Query Neighborhood Hits	1031	Target Neighborhood Hits	342	Shared Neighborhood Hits	136
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

LAD1_HUMAN
NC score	0.069405 (rank : 587)	θ value	0.813845 (rank : 584)
Query Neighborhood Hits	1031	Target Neighborhood Hits	441	Shared Neighborhood Hits	108
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

NCOR2_MOUSE
NC score	0.069023 (rank : 588)	θ value	0.163984 (rank : 457)
Query Neighborhood Hits	1031	Target Neighborhood Hits	790	Shared Neighborhood Hits	178
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

IWS1_HUMAN
NC score	0.068830 (rank : 589)	θ value	θ > 10 (rank : 1148)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1241	Shared Neighborhood Hits	206
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LPP_HUMAN
NC score	0.068582 (rank : 590)	θ value	2.36792 (rank : 719)
Query Neighborhood Hits	1031	Target Neighborhood Hits	775	Shared Neighborhood Hits	275
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MLKL_HUMAN
NC score	0.068558 (rank : 591)	θ value	θ > 10 (rank : 1198)
Query Neighborhood Hits	1031	Target Neighborhood Hits	600	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

TARA_MOUSE
NC score	0.068496 (rank : 592)	θ value	4.03905 (rank : 850)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1133	Shared Neighborhood Hits	225
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TIE1_MOUSE
NC score	0.068485 (rank : 593)	θ value	θ > 10 (rank : 1287)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1266	Shared Neighborhood Hits	107
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_HUMAN
NC score	0.068426 (rank : 594)	θ value	θ > 10 (rank : 1286)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1241	Shared Neighborhood Hits	108
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

VASP_HUMAN
NC score	0.068309 (rank : 595)	θ value	5.27518 (rank : 906)
Query Neighborhood Hits	1031	Target Neighborhood Hits	201	Shared Neighborhood Hits	99
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

CD248_MOUSE
NC score	0.068155 (rank : 596)	θ value	4.03905 (rank : 809)
Query Neighborhood Hits	1031	Target Neighborhood Hits	578	Shared Neighborhood Hits	182
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CRSP2_HUMAN
NC score	0.068139 (rank : 597)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	1031	Target Neighborhood Hits	380	Shared Neighborhood Hits	167
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

VASP_MOUSE
NC score	0.067763 (rank : 598)	θ value	0.365318 (rank : 513)
Query Neighborhood Hits	1031	Target Neighborhood Hits	195	Shared Neighborhood Hits	93
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

DMRTD_HUMAN
NC score	0.067741 (rank : 599)	θ value	1.38821 (rank : 636)
Query Neighborhood Hits	1031	Target Neighborhood Hits	216	Shared Neighborhood Hits	111
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

TIE2_MOUSE
NC score	0.067629 (rank : 600)	θ value	θ > 10 (rank : 1289)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1204	Shared Neighborhood Hits	102
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TP53B_MOUSE
NC score	0.067590 (rank : 601)	θ value	0.62314 (rank : 564)
Query Neighborhood Hits	1031	Target Neighborhood Hits	644	Shared Neighborhood Hits	166
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SEPT9_HUMAN
NC score	0.067502 (rank : 602)	θ value	0.00175202 (rank : 299)
Query Neighborhood Hits	1031	Target Neighborhood Hits	706	Shared Neighborhood Hits	248
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TIE2_HUMAN
NC score	0.067378 (rank : 603)	θ value	θ > 10 (rank : 1288)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1192	Shared Neighborhood Hits	101
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

KI67_HUMAN
NC score	0.067211 (rank : 604)	θ value	θ > 10 (rank : 1158)
Query Neighborhood Hits	1031	Target Neighborhood Hits	581	Shared Neighborhood Hits	124
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

CG1_HUMAN
NC score	0.067165 (rank : 605)	θ value	0.813845 (rank : 575)
Query Neighborhood Hits	1031	Target Neighborhood Hits	222	Shared Neighborhood Hits	105
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

ENAM_MOUSE
NC score	0.067150 (rank : 606)	θ value	0.0736092 (rank : 404)
Query Neighborhood Hits	1031	Target Neighborhood Hits	229	Shared Neighborhood Hits	95
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

DOT1L_HUMAN
NC score	0.067024 (rank : 607)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	1031	Target Neighborhood Hits	660	Shared Neighborhood Hits	173
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

SMAP1_MOUSE
NC score	0.066785 (rank : 608)	θ value	4.03905 (rank : 845)
Query Neighborhood Hits	1031	Target Neighborhood Hits	120	Shared Neighborhood Hits	51
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

MAP4_MOUSE
NC score	0.066757 (rank : 609)	θ value	θ > 10 (rank : 1187)
Query Neighborhood Hits	1031	Target Neighborhood Hits	409	Shared Neighborhood Hits	127
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

LIPB2_HUMAN
NC score	0.066675 (rank : 610)	θ value	0.00035302 (rank : 278)
Query Neighborhood Hits	1031	Target Neighborhood Hits	599	Shared Neighborhood Hits	74
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

IRAK3_HUMAN
NC score	0.066651 (rank : 611)	θ value	θ > 10 (rank : 1144)
Query Neighborhood Hits	1031	Target Neighborhood Hits	644	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

SGIP1_HUMAN
NC score	0.066592 (rank : 612)	θ value	θ > 10 (rank : 1261)
Query Neighborhood Hits	1031	Target Neighborhood Hits	198	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

MAST4_HUMAN
NC score	0.066569 (rank : 613)	θ value	1.29631e-06 (rank : 216)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1804	Shared Neighborhood Hits	362
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

T22D4_HUMAN
NC score	0.066512 (rank : 614)	θ value	5.27518 (rank : 900)
Query Neighborhood Hits	1031	Target Neighborhood Hits	403	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

AATK_HUMAN
NC score	0.066384 (rank : 615)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1243	Shared Neighborhood Hits	270
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

CO039_HUMAN
NC score	0.066176 (rank : 616)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	1031	Target Neighborhood Hits	264	Shared Neighborhood Hits	131
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

TF65_HUMAN
NC score	0.066169 (rank : 617)	θ value	θ > 10 (rank : 1283)
Query Neighborhood Hits	1031	Target Neighborhood Hits	115	Shared Neighborhood Hits	54
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

SMR1_MOUSE
NC score	0.066024 (rank : 618)	θ value	4.03905 (rank : 846)
Query Neighborhood Hits	1031	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

CK024_MOUSE
NC score	0.065900 (rank : 619)	θ value	0.62314 (rank : 542)
Query Neighborhood Hits	1031	Target Neighborhood Hits	307	Shared Neighborhood Hits	99
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

RIPK2_MOUSE
NC score	0.065751 (rank : 620)	θ value	θ > 10 (rank : 1239)
Query Neighborhood Hits	1031	Target Neighborhood Hits	776	Shared Neighborhood Hits	77
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

TCRG1_MOUSE
NC score	0.065745 (rank : 621)	θ value	0.62314 (rank : 563)
Query Neighborhood Hits	1031	Target Neighborhood Hits	947	Shared Neighborhood Hits	175
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

SF01_HUMAN
NC score	0.065711 (rank : 622)	θ value	θ > 10 (rank : 1259)
Query Neighborhood Hits	1031	Target Neighborhood Hits	287	Shared Neighborhood Hits	137
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

PDC6I_MOUSE
NC score	0.065566 (rank : 623)	θ value	1.81305 (rank : 687)
Query Neighborhood Hits	1031	Target Neighborhood Hits	275	Shared Neighborhood Hits	108
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

IRAK3_MOUSE
NC score	0.065218 (rank : 624)	θ value	θ > 10 (rank : 1145)
Query Neighborhood Hits	1031	Target Neighborhood Hits	628	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

TRPC4_MOUSE
NC score	0.065210 (rank : 625)	θ value	0.62314 (rank : 566)
Query Neighborhood Hits	1031	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
NC score	0.065062 (rank : 626)	θ value	0.62314 (rank : 565)
Query Neighborhood Hits	1031	Target Neighborhood Hits	140	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

MNT_MOUSE
NC score	0.064958 (rank : 627)	θ value	θ > 10 (rank : 1202)
Query Neighborhood Hits	1031	Target Neighborhood Hits	432	Shared Neighborhood Hits	155
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

IRAK2_HUMAN
NC score	0.064909 (rank : 628)	θ value	2.36792 (rank : 717)
Query Neighborhood Hits	1031	Target Neighborhood Hits	714	Shared Neighborhood Hits	86
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

M3K10_HUMAN
NC score	0.064895 (rank : 629)	θ value	θ > 10 (rank : 1176)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1071	Shared Neighborhood Hits	144
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

PCQAP_MOUSE
NC score	0.064833 (rank : 630)	θ value	θ > 10 (rank : 1219)
Query Neighborhood Hits	1031	Target Neighborhood Hits	506	Shared Neighborhood Hits	153
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

CITE4_HUMAN
NC score	0.064818 (rank : 631)	θ value	0.365318 (rank : 499)
Query Neighborhood Hits	1031	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q96RK1	Gene names	CITED4, MRG2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

LIPB2_MOUSE
NC score	0.064755 (rank : 632)	θ value	0.00390308 (rank : 314)
Query Neighborhood Hits	1031	Target Neighborhood Hits	570	Shared Neighborhood Hits	75
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

TM108_HUMAN
NC score	0.064747 (rank : 633)	θ value	4.03905 (rank : 852)
Query Neighborhood Hits	1031	Target Neighborhood Hits	166	Shared Neighborhood Hits	88
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

MAVS_HUMAN
NC score	0.064718 (rank : 634)	θ value	5.27518 (rank : 881)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

HSF1_MOUSE
NC score	0.064699 (rank : 635)	θ value	0.00665767 (rank : 330)
Query Neighborhood Hits	1031	Target Neighborhood Hits	267	Shared Neighborhood Hits	109
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

JPH2_HUMAN
NC score	0.064635 (rank : 636)	θ value	4.03905 (rank : 831)
Query Neighborhood Hits	1031	Target Neighborhood Hits	639	Shared Neighborhood Hits	250
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

ABL1_MOUSE
NC score	0.064535 (rank : 637)	θ value	4.03905 (rank : 801)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1178	Shared Neighborhood Hits	185
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ATX2_HUMAN
NC score	0.064534 (rank : 638)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	1031	Target Neighborhood Hits	375	Shared Neighborhood Hits	135
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

TNK1_HUMAN
NC score	0.064492 (rank : 639)	θ value	θ > 10 (rank : 1292)
Query Neighborhood Hits	1031	Target Neighborhood Hits	815	Shared Neighborhood Hits	93
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

BIN1_HUMAN
NC score	0.064307 (rank : 640)	θ value	0.0148317 (rank : 352)
Query Neighborhood Hits	1031	Target Neighborhood Hits	335	Shared Neighborhood Hits	103
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

TCRG1_HUMAN
NC score	0.064144 (rank : 641)	θ value	0.47712 (rank : 535)
Query Neighborhood Hits	1031	Target Neighborhood Hits	929	Shared Neighborhood Hits	157
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

ABL1_HUMAN
NC score	0.063953 (rank : 642)	θ value	1.38821 (rank : 629)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1220	Shared Neighborhood Hits	198
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

EFS_MOUSE
NC score	0.063786 (rank : 643)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	1031	Target Neighborhood Hits	389	Shared Neighborhood Hits	151
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

MILK1_HUMAN
NC score	0.063745 (rank : 644)	θ value	θ > 10 (rank : 1197)
Query Neighborhood Hits	1031	Target Neighborhood Hits	427	Shared Neighborhood Hits	159
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

ERBB2_HUMAN
NC score	0.063694 (rank : 645)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1073	Shared Neighborhood Hits	155
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

SREC2_MOUSE
NC score	0.063632 (rank : 646)	θ value	0.0330416 (rank : 379)
Query Neighborhood Hits	1031	Target Neighborhood Hits	605	Shared Neighborhood Hits	116
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

RTN4_HUMAN
NC score	0.063294 (rank : 647)	θ value	0.0961366 (rank : 421)
Query Neighborhood Hits	1031	Target Neighborhood Hits	357	Shared Neighborhood Hits	126
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

IF4G1_HUMAN
NC score	0.063178 (rank : 648)	θ value	0.813845 (rank : 582)
Query Neighborhood Hits	1031	Target Neighborhood Hits	347	Shared Neighborhood Hits	135
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

M3K9_HUMAN
NC score	0.063143 (rank : 649)	θ value	θ > 10 (rank : 1182)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1123	Shared Neighborhood Hits	170
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

CT032_HUMAN
NC score	0.063041 (rank : 650)	θ value	0.279714 (rank : 485)
Query Neighborhood Hits	1031	Target Neighborhood Hits	235	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

ERBB4_HUMAN
NC score	0.063005 (rank : 651)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	1031	Target Neighborhood Hits	910	Shared Neighborhood Hits	92
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

YES_HUMAN
NC score	0.062896 (rank : 652)	θ value	θ > 10 (rank : 1313)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1059	Shared Neighborhood Hits	133
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

M3KL4_HUMAN
NC score	0.062787 (rank : 653)	θ value	θ > 10 (rank : 1183)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1087	Shared Neighborhood Hits	145
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

SMAP1_HUMAN
NC score	0.062772 (rank : 654)	θ value	θ > 10 (rank : 1262)
Query Neighborhood Hits	1031	Target Neighborhood Hits	98	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

FYN_MOUSE
NC score	0.062673 (rank : 655)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1073	Shared Neighborhood Hits	129
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

YES_MOUSE
NC score	0.062619 (rank : 656)	θ value	θ > 10 (rank : 1314)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1052	Shared Neighborhood Hits	128
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

TXK_HUMAN
NC score	0.062558 (rank : 657)	θ value	θ > 10 (rank : 1304)
Query Neighborhood Hits	1031	Target Neighborhood Hits	971	Shared Neighborhood Hits	112
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

FGR_MOUSE
NC score	0.062427 (rank : 658)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1069	Shared Neighborhood Hits	128
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

CNOT3_MOUSE
NC score	0.062342 (rank : 659)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	1031	Target Neighborhood Hits	504	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

TRDN_HUMAN
NC score	0.062332 (rank : 660)	θ value	θ > 10 (rank : 1295)
Query Neighborhood Hits	1031	Target Neighborhood Hits	542	Shared Neighborhood Hits	77
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

SYP2L_HUMAN
NC score	0.062281 (rank : 661)	θ value	2.36792 (rank : 732)
Query Neighborhood Hits	1031	Target Neighborhood Hits	400	Shared Neighborhood Hits	154
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

NELFA_HUMAN
NC score	0.062274 (rank : 662)	θ value	3.0926 (rank : 780)
Query Neighborhood Hits	1031	Target Neighborhood Hits	161	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

CNOT3_HUMAN
NC score	0.062224 (rank : 663)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	1031	Target Neighborhood Hits	425	Shared Neighborhood Hits	115
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

FAK2_HUMAN
NC score	0.062152 (rank : 664)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	1031	Target Neighborhood Hits	847	Shared Neighborhood Hits	85
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

TXK_MOUSE
NC score	0.062064 (rank : 665)	θ value	θ > 10 (rank : 1305)
Query Neighborhood Hits	1031	Target Neighborhood Hits	980	Shared Neighborhood Hits	114
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

FGR_HUMAN
NC score	0.061980 (rank : 666)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1067	Shared Neighborhood Hits	127
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FYN_HUMAN
NC score	0.061933 (rank : 667)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1078	Shared Neighborhood Hits	129
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

SC24A_MOUSE
NC score	0.061929 (rank : 668)	θ value	θ > 10 (rank : 1254)
Query Neighborhood Hits	1031	Target Neighborhood Hits	394	Shared Neighborhood Hits	182
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

BTK_HUMAN
NC score	0.061740 (rank : 669)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1026	Shared Neighborhood Hits	126
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

FAK2_MOUSE
NC score	0.061708 (rank : 670)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	1031	Target Neighborhood Hits	851	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

MLKL_MOUSE
NC score	0.061512 (rank : 671)	θ value	θ > 10 (rank : 1199)
Query Neighborhood Hits	1031	Target Neighborhood Hits	707	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

ZAP70_HUMAN
NC score	0.061498 (rank : 672)	θ value	θ > 10 (rank : 1316)
Query Neighborhood Hits	1031	Target Neighborhood Hits	893	Shared Neighborhood Hits	91
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

PHC2_HUMAN
NC score	0.061489 (rank : 673)	θ value	θ > 10 (rank : 1221)
Query Neighborhood Hits	1031	Target Neighborhood Hits	388	Shared Neighborhood Hits	166
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

IRAK1_HUMAN
NC score	0.061428 (rank : 674)	θ value	θ > 10 (rank : 1142)
Query Neighborhood Hits	1031	Target Neighborhood Hits	820	Shared Neighborhood Hits	107
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

NELFA_MOUSE
NC score	0.061410 (rank : 675)	θ value	8.99809 (rank : 1003)
Query Neighborhood Hits	1031	Target Neighborhood Hits	195	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

FER_HUMAN
NC score	0.061264 (rank : 676)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1278	Shared Neighborhood Hits	117
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

BTK_MOUSE
NC score	0.061175 (rank : 677)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1017	Shared Neighborhood Hits	125
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

FAK1_HUMAN
NC score	0.061153 (rank : 678)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	1031	Target Neighborhood Hits	850	Shared Neighborhood Hits	88
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

ERBB2_MOUSE
NC score	0.061098 (rank : 679)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	1031	Target Neighborhood Hits	918	Shared Neighborhood Hits	98
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

SRC_HUMAN
NC score	0.061089 (rank : 680)	θ value	θ > 10 (rank : 1267)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1058	Shared Neighborhood Hits	131
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

TNK1_MOUSE
NC score	0.060989 (rank : 681)	θ value	θ > 10 (rank : 1293)
Query Neighborhood Hits	1031	Target Neighborhood Hits	806	Shared Neighborhood Hits	86
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

FRK_HUMAN
NC score	0.060987 (rank : 682)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1058	Shared Neighborhood Hits	124
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

RIPK3_HUMAN
NC score	0.060925 (rank : 683)	θ value	θ > 10 (rank : 1240)
Query Neighborhood Hits	1031	Target Neighborhood Hits	828	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

AFF1_MOUSE
NC score	0.060875 (rank : 684)	θ value	2.36792 (rank : 696)
Query Neighborhood Hits	1031	Target Neighborhood Hits	351	Shared Neighborhood Hits	119
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

FAK1_MOUSE
NC score	0.060836 (rank : 685)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	1031	Target Neighborhood Hits	850	Shared Neighborhood Hits	84
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

SMP1L_HUMAN
NC score	0.060770 (rank : 686)	θ value	θ > 10 (rank : 1264)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

RIMB1_HUMAN
NC score	0.060748 (rank : 687)	θ value	0.62314 (rank : 559)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1479	Shared Neighborhood Hits	262
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

HCK_MOUSE
NC score	0.060699 (rank : 688)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1029	Shared Neighborhood Hits	125
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

BAZ2A_MOUSE
NC score	0.060695 (rank : 689)	θ value	1.06291 (rank : 605)
Query Neighborhood Hits	1031	Target Neighborhood Hits	744	Shared Neighborhood Hits	218
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

INSRR_MOUSE
NC score	0.060670 (rank : 690)	θ value	θ > 10 (rank : 1139)
Query Neighborhood Hits	1031	Target Neighborhood Hits	961	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_HUMAN
NC score	0.060667 (rank : 691)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	1031	Target Neighborhood Hits	950	Shared Neighborhood Hits	100
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

DDR1_HUMAN
NC score	0.060658 (rank : 692)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	1031	Target Neighborhood Hits	819	Shared Neighborhood Hits	85
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

ZIM10_HUMAN
NC score	0.060557 (rank : 693)	θ value	θ > 10 (rank : 1318)
Query Neighborhood Hits	1031	Target Neighborhood Hits	577	Shared Neighborhood Hits	228
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

LTK_HUMAN
NC score	0.060530 (rank : 694)	θ value	θ > 10 (rank : 1172)
Query Neighborhood Hits	1031	Target Neighborhood Hits	774	Shared Neighborhood Hits	81
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

ZAP70_MOUSE
NC score	0.060490 (rank : 695)	θ value	θ > 10 (rank : 1317)
Query Neighborhood Hits	1031	Target Neighborhood Hits	905	Shared Neighborhood Hits	91
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

INSR_HUMAN
NC score	0.060453 (rank : 696)	θ value	θ > 10 (rank : 1140)
Query Neighborhood Hits	1031	Target Neighborhood Hits	963	Shared Neighborhood Hits	92
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

EFS_HUMAN
NC score	0.060440 (rank : 697)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	1031	Target Neighborhood Hits	348	Shared Neighborhood Hits	141
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

TEC_HUMAN
NC score	0.060428 (rank : 698)	θ value	θ > 10 (rank : 1279)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1006	Shared Neighborhood Hits	113
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

LTK_MOUSE
NC score	0.060409 (rank : 699)	θ value	θ > 10 (rank : 1173)
Query Neighborhood Hits	1031	Target Neighborhood Hits	770	Shared Neighborhood Hits	84
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

NFRKB_MOUSE
NC score	0.060333 (rank : 700)	θ value	1.81305 (rank : 685)
Query Neighborhood Hits	1031	Target Neighborhood Hits	393	Shared Neighborhood Hits	145
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

DDR1_MOUSE
NC score	0.060323 (rank : 701)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	1031	Target Neighborhood Hits	818	Shared Neighborhood Hits	85
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

PTN23_HUMAN
NC score	0.060297 (rank : 702)	θ value	0.0736092 (rank : 407)
Query Neighborhood Hits	1031	Target Neighborhood Hits	646	Shared Neighborhood Hits	195
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RIPK3_MOUSE
NC score	0.060284 (rank : 703)	θ value	θ > 10 (rank : 1241)
Query Neighborhood Hits	1031	Target Neighborhood Hits	867	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

RIN3_MOUSE
NC score	0.060150 (rank : 704)	θ value	5.27518 (rank : 889)
Query Neighborhood Hits	1031	Target Neighborhood Hits	239	Shared Neighborhood Hits	121
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

AMPH_HUMAN
NC score	0.060137 (rank : 705)	θ value	1.06291 (rank : 602)
Query Neighborhood Hits	1031	Target Neighborhood Hits	455	Shared Neighborhood Hits	130
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

SRC_MOUSE
NC score	0.060128 (rank : 706)	θ value	θ > 10 (rank : 1268)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1033	Shared Neighborhood Hits	125
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

ROR2_MOUSE
NC score	0.060111 (rank : 707)	θ value	θ > 10 (rank : 1247)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1000	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

SAM14_MOUSE
NC score	0.060109 (rank : 708)	θ value	θ > 10 (rank : 1253)
Query Neighborhood Hits	1031	Target Neighborhood Hits	91	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

HCK_HUMAN
NC score	0.060038 (rank : 709)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1035	Shared Neighborhood Hits	125
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

EGFR_HUMAN
NC score	0.059927 (rank : 710)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	1031	Target Neighborhood Hits	939	Shared Neighborhood Hits	89
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

LCK_MOUSE
NC score	0.059899 (rank : 711)	θ value	θ > 10 (rank : 1170)
Query Neighborhood Hits	1031	Target Neighborhood Hits	981	Shared Neighborhood Hits	109
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

EGFR_MOUSE
NC score	0.059805 (rank : 712)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	1031	Target Neighborhood Hits	927	Shared Neighborhood Hits	90
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ITK_HUMAN
NC score	0.059803 (rank : 713)	θ value	θ > 10 (rank : 1146)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1016	Shared Neighborhood Hits	111
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ROR1_HUMAN
NC score	0.059774 (rank : 714)	θ value	θ > 10 (rank : 1244)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1018	Shared Neighborhood Hits	86
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

INSR_MOUSE
NC score	0.059706 (rank : 715)	θ value	θ > 10 (rank : 1141)
Query Neighborhood Hits	1031	Target Neighborhood Hits	968	Shared Neighborhood Hits	91
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TEC_MOUSE
NC score	0.059658 (rank : 716)	θ value	θ > 10 (rank : 1280)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1006	Shared Neighborhood Hits	113
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

RTN4_MOUSE
NC score	0.059647 (rank : 717)	θ value	0.813845 (rank : 591)
Query Neighborhood Hits	1031	Target Neighborhood Hits	341	Shared Neighborhood Hits	125
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

ROR1_MOUSE
NC score	0.059640 (rank : 718)	θ value	θ > 10 (rank : 1245)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1025	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

GUC2G_MOUSE
NC score	0.059493 (rank : 719)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	1031	Target Neighborhood Hits	644	Shared Neighborhood Hits	69
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

LCK_HUMAN
NC score	0.059412 (rank : 720)	θ value	θ > 10 (rank : 1169)
Query Neighborhood Hits	1031	Target Neighborhood Hits	987	Shared Neighborhood Hits	111
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

ITK_MOUSE
NC score	0.059317 (rank : 721)	θ value	θ > 10 (rank : 1147)
Query Neighborhood Hits	1031	Target Neighborhood Hits	985	Shared Neighborhood Hits	106
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

AATK_MOUSE
NC score	0.059282 (rank : 722)	θ value	6.88961 (rank : 910)
Query Neighborhood Hits	1031	Target Neighborhood Hits	942	Shared Neighborhood Hits	139
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ROR2_HUMAN
NC score	0.059221 (rank : 723)	θ value	θ > 10 (rank : 1246)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1014	Shared Neighborhood Hits	88
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

MERTK_HUMAN
NC score	0.059135 (rank : 724)	θ value	θ > 10 (rank : 1193)
Query Neighborhood Hits	1031	Target Neighborhood Hits	988	Shared Neighborhood Hits	87
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

CT174_HUMAN
NC score	0.059104 (rank : 725)	θ value	0.47712 (rank : 522)
Query Neighborhood Hits	1031	Target Neighborhood Hits	181	Shared Neighborhood Hits	73
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

BLK_HUMAN
NC score	0.059020 (rank : 726)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	1031	Target Neighborhood Hits	994	Shared Neighborhood Hits	116
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

MET_HUMAN
NC score	0.059001 (rank : 727)	θ value	θ > 10 (rank : 1195)
Query Neighborhood Hits	1031	Target Neighborhood Hits	831	Shared Neighborhood Hits	80
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MERTK_MOUSE
NC score	0.058950 (rank : 728)	θ value	θ > 10 (rank : 1194)
Query Neighborhood Hits	1031	Target Neighborhood Hits	974	Shared Neighborhood Hits	84
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

STAC_HUMAN
NC score	0.058880 (rank : 729)	θ value	0.163984 (rank : 462)
Query Neighborhood Hits	1031	Target Neighborhood Hits	276	Shared Neighborhood Hits	65
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

KSYK_MOUSE
NC score	0.058879 (rank : 730)	θ value	θ > 10 (rank : 1164)
Query Neighborhood Hits	1031	Target Neighborhood Hits	944	Shared Neighborhood Hits	106
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

GTSE1_HUMAN
NC score	0.058848 (rank : 731)	θ value	1.81305 (rank : 676)
Query Neighborhood Hits	1031	Target Neighborhood Hits	193	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

LYN_MOUSE
NC score	0.058827 (rank : 732)	θ value	θ > 10 (rank : 1175)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1023	Shared Neighborhood Hits	121
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MET_MOUSE
NC score	0.058783 (rank : 733)	θ value	θ > 10 (rank : 1196)
Query Neighborhood Hits	1031	Target Neighborhood Hits	844	Shared Neighborhood Hits	83
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

STAC_MOUSE
NC score	0.058779 (rank : 734)	θ value	0.21417 (rank : 477)
Query Neighborhood Hits	1031	Target Neighborhood Hits	268	Shared Neighborhood Hits	64
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

UFO_MOUSE
NC score	0.058759 (rank : 735)	θ value	θ > 10 (rank : 1310)
Query Neighborhood Hits	1031	Target Neighborhood Hits	988	Shared Neighborhood Hits	92
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

WNK4_HUMAN
NC score	0.058758 (rank : 736)	θ value	3.0926 (rank : 798)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1043	Shared Neighborhood Hits	202
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

UFO_HUMAN
NC score	0.058729 (rank : 737)	θ value	θ > 10 (rank : 1309)
Query Neighborhood Hits	1031	Target Neighborhood Hits	981	Shared Neighborhood Hits	99
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

SMP1L_MOUSE
NC score	0.058720 (rank : 738)	θ value	θ > 10 (rank : 1265)
Query Neighborhood Hits	1031	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

LYN_HUMAN
NC score	0.058663 (rank : 739)	θ value	θ > 10 (rank : 1174)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1022	Shared Neighborhood Hits	119
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

FES_MOUSE
NC score	0.058592 (rank : 740)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	1031	Target Neighborhood Hits	980	Shared Neighborhood Hits	101
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

PTK6_HUMAN
NC score	0.058592 (rank : 741)	θ value	θ > 10 (rank : 1224)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1020	Shared Neighborhood Hits	121
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

DDR2_HUMAN
NC score	0.058572 (rank : 742)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	1031	Target Neighborhood Hits	818	Shared Neighborhood Hits	78
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

ALK_MOUSE
NC score	0.058524 (rank : 743)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	1031	Target Neighborhood Hits	811	Shared Neighborhood Hits	87
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

PTK6_MOUSE
NC score	0.058472 (rank : 744)	θ value	θ > 10 (rank : 1225)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1026	Shared Neighborhood Hits	120
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

LTBP4_MOUSE
NC score	0.058418 (rank : 745)	θ value	0.279714 (rank : 489)
Query Neighborhood Hits	1031	Target Neighborhood Hits	607	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

ROS_HUMAN
NC score	0.058397 (rank : 746)	θ value	θ > 10 (rank : 1248)
Query Neighborhood Hits	1031	Target Neighborhood Hits	907	Shared Neighborhood Hits	84
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

APXL_HUMAN
NC score	0.058270 (rank : 747)	θ value	0.0563607 (rank : 392)
Query Neighborhood Hits	1031	Target Neighborhood Hits	553	Shared Neighborhood Hits	129
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

DDR2_MOUSE
NC score	0.058179 (rank : 748)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	1031	Target Neighborhood Hits	813	Shared Neighborhood Hits	80
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

RYK_HUMAN
NC score	0.058178 (rank : 749)	θ value	θ > 10 (rank : 1249)
Query Neighborhood Hits	1031	Target Neighborhood Hits	701	Shared Neighborhood Hits	70
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

M3K7_MOUSE
NC score	0.058176 (rank : 750)	θ value	θ > 10 (rank : 1181)
Query Neighborhood Hits	1031	Target Neighborhood Hits	892	Shared Neighborhood Hits	84
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

NRX2B_HUMAN
NC score	0.058170 (rank : 751)	θ value	4.03905 (rank : 840)
Query Neighborhood Hits	1031	Target Neighborhood Hits	481	Shared Neighborhood Hits	202
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

M3K7_HUMAN
NC score	0.058118 (rank : 752)	θ value	θ > 10 (rank : 1180)
Query Neighborhood Hits	1031	Target Neighborhood Hits	892	Shared Neighborhood Hits	83
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

ZAN_MOUSE
NC score	0.058094 (rank : 753)	θ value	θ > 10 (rank : 1315)
Query Neighborhood Hits	1031	Target Neighborhood Hits	808	Shared Neighborhood Hits	93
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MATK_HUMAN
NC score	0.058073 (rank : 754)	θ value	θ > 10 (rank : 1190)
Query Neighborhood Hits	1031	Target Neighborhood Hits	954	Shared Neighborhood Hits	98
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

BLK_MOUSE
NC score	0.058011 (rank : 755)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	1031	Target Neighborhood Hits	992	Shared Neighborhood Hits	112
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

KSYK_HUMAN
NC score	0.057983 (rank : 756)	θ value	θ > 10 (rank : 1163)
Query Neighborhood Hits	1031	Target Neighborhood Hits	901	Shared Neighborhood Hits	88
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

TYRO3_MOUSE
NC score	0.057937 (rank : 757)	θ value	θ > 10 (rank : 1308)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1007	Shared Neighborhood Hits	84
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

ALK_HUMAN
NC score	0.057917 (rank : 758)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	1031	Target Neighborhood Hits	795	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

IGF1R_MOUSE
NC score	0.057884 (rank : 759)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	1031	Target Neighborhood Hits	973	Shared Neighborhood Hits	95
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

NTRK1_HUMAN
NC score	0.057872 (rank : 760)	θ value	θ > 10 (rank : 1213)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1023	Shared Neighborhood Hits	82
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

MEGF9_HUMAN
NC score	0.057856 (rank : 761)	θ value	θ > 10 (rank : 1192)
Query Neighborhood Hits	1031	Target Neighborhood Hits	557	Shared Neighborhood Hits	142
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SPRR3_HUMAN
NC score	0.057798 (rank : 762)	θ value	1.06291 (rank : 624)
Query Neighborhood Hits	1031	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

PER3_HUMAN
NC score	0.057786 (rank : 763)	θ value	5.27518 (rank : 886)
Query Neighborhood Hits	1031	Target Neighborhood Hits	479	Shared Neighborhood Hits	183
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

ABL2_HUMAN
NC score	0.057780 (rank : 764)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1045	Shared Neighborhood Hits	129
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

TPO_MOUSE
NC score	0.057744 (rank : 765)	θ value	2.36792 (rank : 735)
Query Neighborhood Hits	1031	Target Neighborhood Hits	258	Shared Neighborhood Hits	125
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

MATK_MOUSE
NC score	0.057661 (rank : 766)	θ value	θ > 10 (rank : 1191)
Query Neighborhood Hits	1031	Target Neighborhood Hits	952	Shared Neighborhood Hits	97
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

FES_HUMAN
NC score	0.057658 (rank : 767)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	1031	Target Neighborhood Hits	978	Shared Neighborhood Hits	89
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

RYK_MOUSE
NC score	0.057623 (rank : 768)	θ value	θ > 10 (rank : 1250)
Query Neighborhood Hits	1031	Target Neighborhood Hits	715	Shared Neighborhood Hits	71
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

TYRO3_HUMAN
NC score	0.057532 (rank : 769)	θ value	θ > 10 (rank : 1307)
Query Neighborhood Hits	1031	Target Neighborhood Hits	995	Shared Neighborhood Hits	82
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

IGF1R_HUMAN
NC score	0.057474 (rank : 770)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	1031	Target Neighborhood Hits	977	Shared Neighborhood Hits	94
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

NIPBL_HUMAN
NC score	0.057471 (rank : 771)	θ value	8.99809 (rank : 1005)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1311	Shared Neighborhood Hits	213
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

FMNL_MOUSE
NC score	0.057225 (rank : 772)	θ value	4.03905 (rank : 824)
Query Neighborhood Hits	1031	Target Neighborhood Hits	428	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

BMX_MOUSE
NC score	0.057197 (rank : 773)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	1031	Target Neighborhood Hits	912	Shared Neighborhood Hits	93
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

MAP1B_HUMAN
NC score	0.057075 (rank : 774)	θ value	5.27518 (rank : 880)
Query Neighborhood Hits	1031	Target Neighborhood Hits	903	Shared Neighborhood Hits	155
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

CSK_HUMAN
NC score	0.057071 (rank : 775)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	108
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

ZAN_HUMAN
NC score	0.057061 (rank : 776)	θ value	1.81305 (rank : 695)
Query Neighborhood Hits	1031	Target Neighborhood Hits	679	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

MLTK_HUMAN
NC score	0.056953 (rank : 777)	θ value	θ > 10 (rank : 1200)
Query Neighborhood Hits	1031	Target Neighborhood Hits	911	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

RON_MOUSE
NC score	0.056857 (rank : 778)	θ value	θ > 10 (rank : 1243)
Query Neighborhood Hits	1031	Target Neighborhood Hits	836	Shared Neighborhood Hits	82
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

BMX_HUMAN
NC score	0.056837 (rank : 779)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	1031	Target Neighborhood Hits	942	Shared Neighborhood Hits	96
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

SAM14_HUMAN
NC score	0.056821 (rank : 780)	θ value	θ > 10 (rank : 1252)
Query Neighborhood Hits	1031	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

RON_HUMAN
NC score	0.056819 (rank : 781)	θ value	θ > 10 (rank : 1242)
Query Neighborhood Hits	1031	Target Neighborhood Hits	842	Shared Neighborhood Hits	85
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

LR37A_HUMAN
NC score	0.056728 (rank : 782)	θ value	1.38821 (rank : 642)
Query Neighborhood Hits	1031	Target Neighborhood Hits	720	Shared Neighborhood Hits	183
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

ENAH_HUMAN
NC score	0.056704 (rank : 783)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	1031	Target Neighborhood Hits	784	Shared Neighborhood Hits	177
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

RAF1_HUMAN
NC score	0.056695 (rank : 784)	θ value	θ > 10 (rank : 1226)
Query Neighborhood Hits	1031	Target Neighborhood Hits	886	Shared Neighborhood Hits	90
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
NC score	0.056594 (rank : 785)	θ value	θ > 10 (rank : 1227)
Query Neighborhood Hits	1031	Target Neighborhood Hits	886	Shared Neighborhood Hits	90
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

BRAF1_HUMAN
NC score	0.056559 (rank : 786)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	1031	Target Neighborhood Hits	883	Shared Neighborhood Hits	91
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

MLTK_MOUSE
NC score	0.056532 (rank : 787)	θ value	θ > 10 (rank : 1201)
Query Neighborhood Hits	1031	Target Neighborhood Hits	874	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

ENL_HUMAN
NC score	0.056511 (rank : 788)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	93
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

ACINU_MOUSE
NC score	0.056443 (rank : 789)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	1031	Target Neighborhood Hits	712	Shared Neighborhood Hits	143
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

RET_MOUSE
NC score	0.056411 (rank : 790)	θ value	θ > 10 (rank : 1235)
Query Neighborhood Hits	1031	Target Neighborhood Hits	884	Shared Neighborhood Hits	82
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

ZN645_HUMAN
NC score	0.056330 (rank : 791)	θ value	1.38821 (rank : 660)
Query Neighborhood Hits	1031	Target Neighborhood Hits	265	Shared Neighborhood Hits	104
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

GUC2C_HUMAN
NC score	0.056312 (rank : 792)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	1031	Target Neighborhood Hits	624	Shared Neighborhood Hits	64
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

SRMS_HUMAN
NC score	0.056220 (rank : 793)	θ value	θ > 10 (rank : 1269)
Query Neighborhood Hits	1031	Target Neighborhood Hits	946	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

IRAK1_MOUSE
NC score	0.056172 (rank : 794)	θ value	θ > 10 (rank : 1143)
Query Neighborhood Hits	1031	Target Neighborhood Hits	784	Shared Neighborhood Hits	87
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

S23IP_HUMAN
NC score	0.056118 (rank : 795)	θ value	θ > 10 (rank : 1251)
Query Neighborhood Hits	1031	Target Neighborhood Hits	134	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

REL_MOUSE
NC score	0.056103 (rank : 796)	θ value	θ > 10 (rank : 1231)
Query Neighborhood Hits	1031	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

CSK_MOUSE
NC score	0.056027 (rank : 797)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	108
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CT151_HUMAN
NC score	0.055968 (rank : 798)	θ value	3.0926 (rank : 750)
Query Neighborhood Hits	1031	Target Neighborhood Hits	382	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

SH3K1_HUMAN
NC score	0.055953 (rank : 799)	θ value	5.27518 (rank : 892)
Query Neighborhood Hits	1031	Target Neighborhood Hits	341	Shared Neighborhood Hits	82
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SRMS_MOUSE
NC score	0.055948 (rank : 800)	θ value	θ > 10 (rank : 1270)
Query Neighborhood Hits	1031	Target Neighborhood Hits	964	Shared Neighborhood Hits	101
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

RET_HUMAN
NC score	0.055934 (rank : 801)	θ value	θ > 10 (rank : 1234)
Query Neighborhood Hits	1031	Target Neighborhood Hits	873	Shared Neighborhood Hits	80
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

M3K12_HUMAN
NC score	0.055791 (rank : 802)	θ value	θ > 10 (rank : 1177)
Query Neighborhood Hits	1031	Target Neighborhood Hits	940	Shared Neighborhood Hits	118
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

IF35_MOUSE
NC score	0.055738 (rank : 803)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	1031	Target Neighborhood Hits	210	Shared Neighborhood Hits	111
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

CENA1_HUMAN
NC score	0.055733 (rank : 804)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	1031	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CASL_MOUSE
NC score	0.055724 (rank : 805)	θ value	0.125558 (rank : 433)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

MTSS1_HUMAN
NC score	0.055562 (rank : 806)	θ value	θ > 10 (rank : 1204)
Query Neighborhood Hits	1031	Target Neighborhood Hits	504	Shared Neighborhood Hits	176
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

ERBB3_HUMAN
NC score	0.055479 (rank : 807)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	1031	Target Neighborhood Hits	918	Shared Neighborhood Hits	89
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

SF01_MOUSE
NC score	0.055461 (rank : 808)	θ value	θ > 10 (rank : 1260)
Query Neighborhood Hits	1031	Target Neighborhood Hits	240	Shared Neighborhood Hits	108
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ATX7_HUMAN
NC score	0.055444 (rank : 809)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	1031	Target Neighborhood Hits	351	Shared Neighborhood Hits	158
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

ARAF_HUMAN
NC score	0.055374 (rank : 810)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	1031	Target Neighborhood Hits	924	Shared Neighborhood Hits	101
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

SETD2_HUMAN
NC score	0.055374 (rank : 811)	θ value	θ > 10 (rank : 1258)
Query Neighborhood Hits	1031	Target Neighborhood Hits	412	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

MAP1B_MOUSE
NC score	0.055367 (rank : 812)	θ value	θ > 10 (rank : 1185)
Query Neighborhood Hits	1031	Target Neighborhood Hits	977	Shared Neighborhood Hits	172
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TMAP1_HUMAN
NC score	0.055255 (rank : 813)	θ value	θ > 10 (rank : 1291)
Query Neighborhood Hits	1031	Target Neighborhood Hits	140	Shared Neighborhood Hits	58
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

PDC6I_HUMAN
NC score	0.055228 (rank : 814)	θ value	θ > 10 (rank : 1220)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

M3K12_MOUSE
NC score	0.055214 (rank : 815)	θ value	θ > 10 (rank : 1178)
Query Neighborhood Hits	1031	Target Neighborhood Hits	957	Shared Neighborhood Hits	109
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

ERBB3_MOUSE
NC score	0.055203 (rank : 816)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	1031	Target Neighborhood Hits	898	Shared Neighborhood Hits	89
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ULK1_MOUSE
NC score	0.055175 (rank : 817)	θ value	0.0736092 (rank : 412)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1214	Shared Neighborhood Hits	256
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

NTRK3_HUMAN
NC score	0.055146 (rank : 818)	θ value	θ > 10 (rank : 1216)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1115	Shared Neighborhood Hits	86
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

GUC2F_HUMAN
NC score	0.054925 (rank : 819)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	1031	Target Neighborhood Hits	740	Shared Neighborhood Hits	73
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GNAS1_MOUSE
NC score	0.054902 (rank : 820)	θ value	0.125558 (rank : 437)
Query Neighborhood Hits	1031	Target Neighborhood Hits	651	Shared Neighborhood Hits	235
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

JADE2_MOUSE
NC score	0.054901 (rank : 821)	θ value	0.125558 (rank : 440)
Query Neighborhood Hits	1031	Target Neighborhood Hits	560	Shared Neighborhood Hits	194
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

CNTRB_MOUSE
NC score	0.054862 (rank : 822)	θ value	0.00665767 (rank : 329)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1029	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

WNK1_HUMAN
NC score	0.054804 (rank : 823)	θ value	θ > 10 (rank : 1312)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1158	Shared Neighborhood Hits	209
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

LTBP2_MOUSE
NC score	0.054800 (rank : 824)	θ value	6.88961 (rank : 942)
Query Neighborhood Hits	1031	Target Neighborhood Hits	617	Shared Neighborhood Hits	100
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PYGO2_HUMAN
NC score	0.054735 (rank : 825)	θ value	8.99809 (rank : 1011)
Query Neighborhood Hits	1031	Target Neighborhood Hits	189	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

NTRK2_HUMAN
NC score	0.054668 (rank : 826)	θ value	θ > 10 (rank : 1214)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1081	Shared Neighborhood Hits	84
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

STAM1_MOUSE
NC score	0.054564 (rank : 827)	θ value	0.365318 (rank : 510)
Query Neighborhood Hits	1031	Target Neighborhood Hits	273	Shared Neighborhood Hits	75
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

NTRK2_MOUSE
NC score	0.054535 (rank : 828)	θ value	θ > 10 (rank : 1215)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1088	Shared Neighborhood Hits	84
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NFAC1_HUMAN
NC score	0.054409 (rank : 829)	θ value	0.00509761 (rank : 326)
Query Neighborhood Hits	1031	Target Neighborhood Hits	312	Shared Neighborhood Hits	139
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

ARAF_MOUSE
NC score	0.054358 (rank : 830)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	1031	Target Neighborhood Hits	874	Shared Neighborhood Hits	85
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

LCE1B_HUMAN
NC score	0.054304 (rank : 831)	θ value	θ > 10 (rank : 1166)
Query Neighborhood Hits	1031	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

TF65_MOUSE
NC score	0.054232 (rank : 832)	θ value	θ > 10 (rank : 1284)
Query Neighborhood Hits	1031	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

LCE1D_HUMAN
NC score	0.054069 (rank : 833)	θ value	θ > 10 (rank : 1168)
Query Neighborhood Hits	1031	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

NSD1_MOUSE
NC score	0.054037 (rank : 834)	θ value	θ > 10 (rank : 1212)
Query Neighborhood Hits	1031	Target Neighborhood Hits	472	Shared Neighborhood Hits	124
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

AN13D_MOUSE
NC score	0.054026 (rank : 835)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	1031	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PD24	Gene names	Ankrd13d
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

ATX7_MOUSE
NC score	0.053986 (rank : 836)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	1031	Target Neighborhood Hits	328	Shared Neighborhood Hits	171
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

ANPRB_MOUSE
NC score	0.053891 (rank : 837)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	1031	Target Neighborhood Hits	607	Shared Neighborhood Hits	65
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

AN13D_HUMAN
NC score	0.053873 (rank : 838)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	1031	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

CO002_HUMAN
NC score	0.053793 (rank : 839)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	1031	Target Neighborhood Hits	387	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

TENX_HUMAN
NC score	0.053754 (rank : 840)	θ value	θ > 10 (rank : 1281)
Query Neighborhood Hits	1031	Target Neighborhood Hits	789	Shared Neighborhood Hits	113
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LCE1C_HUMAN
NC score	0.053702 (rank : 841)	θ value	θ > 10 (rank : 1167)
Query Neighborhood Hits	1031	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

CD2AP_MOUSE
NC score	0.053604 (rank : 842)	θ value	4.03905 (rank : 810)
Query Neighborhood Hits	1031	Target Neighborhood Hits	336	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CO5A2_HUMAN
NC score	0.053557 (rank : 843)	θ value	5.27518 (rank : 866)
Query Neighborhood Hits	1031	Target Neighborhood Hits	760	Shared Neighborhood Hits	211
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CASC3_MOUSE
NC score	0.053542 (rank : 844)	θ value	6.88961 (rank : 920)
Query Neighborhood Hits	1031	Target Neighborhood Hits	333	Shared Neighborhood Hits	120
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

RIPK1_HUMAN
NC score	0.053418 (rank : 845)	θ value	θ > 10 (rank : 1236)
Query Neighborhood Hits	1031	Target Neighborhood Hits	891	Shared Neighborhood Hits	89
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

SMOO_HUMAN
NC score	0.053373 (rank : 846)	θ value	θ > 10 (rank : 1263)
Query Neighborhood Hits	1031	Target Neighborhood Hits	391	Shared Neighborhood Hits	143
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TACC2_MOUSE
NC score	0.053312 (rank : 847)	θ value	θ > 10 (rank : 1273)
Query Neighborhood Hits	1031	Target Neighborhood Hits	774	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

ARMX2_MOUSE
NC score	0.053288 (rank : 848)	θ value	3.0926 (rank : 743)
Query Neighborhood Hits	1031	Target Neighborhood Hits	349	Shared Neighborhood Hits	138
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

PTN23_MOUSE
NC score	0.053238 (rank : 849)	θ value	1.81305 (rank : 690)
Query Neighborhood Hits	1031	Target Neighborhood Hits	726	Shared Neighborhood Hits	231
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MUSK_HUMAN
NC score	0.053143 (rank : 850)	θ value	θ > 10 (rank : 1208)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1074	Shared Neighborhood Hits	79
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

M3K13_HUMAN
NC score	0.053122 (rank : 851)	θ value	θ > 10 (rank : 1179)
Query Neighborhood Hits	1031	Target Neighborhood Hits	911	Shared Neighborhood Hits	95
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

ANPRB_HUMAN
NC score	0.053050 (rank : 852)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	1031	Target Neighborhood Hits	646	Shared Neighborhood Hits	69
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

RFX1_HUMAN
NC score	0.052992 (rank : 853)	θ value	0.365318 (rank : 508)
Query Neighborhood Hits	1031	Target Neighborhood Hits	256	Shared Neighborhood Hits	119
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

STAM1_HUMAN
NC score	0.052911 (rank : 854)	θ value	0.62314 (rank : 562)
Query Neighborhood Hits	1031	Target Neighborhood Hits	271	Shared Neighborhood Hits	70
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

SYN2_HUMAN
NC score	0.052894 (rank : 855)	θ value	5.27518 (rank : 899)
Query Neighborhood Hits	1031	Target Neighborhood Hits	213	Shared Neighborhood Hits	110
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

MUSK_MOUSE
NC score	0.052515 (rank : 856)	θ value	θ > 10 (rank : 1209)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1057	Shared Neighborhood Hits	79
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

CI079_HUMAN
NC score	0.052437 (rank : 857)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	1031	Target Neighborhood Hits	288	Shared Neighborhood Hits	114
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

JAK1_HUMAN
NC score	0.052424 (rank : 858)	θ value	θ > 10 (rank : 1153)
Query Neighborhood Hits	1031	Target Neighborhood Hits	858	Shared Neighborhood Hits	80
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

ENAM_HUMAN
NC score	0.052406 (rank : 859)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	1031	Target Neighborhood Hits	227	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

SNIP_HUMAN
NC score	0.052360 (rank : 860)	θ value	0.0736092 (rank : 410)
Query Neighborhood Hits	1031	Target Neighborhood Hits	313	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SH3K1_MOUSE
NC score	0.052359 (rank : 861)	θ value	5.27518 (rank : 893)
Query Neighborhood Hits	1031	Target Neighborhood Hits	332	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

MOS_HUMAN
NC score	0.052350 (rank : 862)	θ value	θ > 10 (rank : 1203)
Query Neighborhood Hits	1031	Target Neighborhood Hits	829	Shared Neighborhood Hits	80
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

LTB1L_HUMAN
NC score	0.052294 (rank : 863)	θ value	0.163984 (rank : 455)
Query Neighborhood Hits	1031	Target Neighborhood Hits	553	Shared Neighborhood Hits	88
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NFH_HUMAN
NC score	0.052270 (rank : 864)	θ value	θ > 10 (rank : 1210)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1242	Shared Neighborhood Hits	202
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

JAK1_MOUSE
NC score	0.052268 (rank : 865)	θ value	θ > 10 (rank : 1154)
Query Neighborhood Hits	1031	Target Neighborhood Hits	854	Shared Neighborhood Hits	81
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

KSR1_HUMAN
NC score	0.052121 (rank : 866)	θ value	θ > 10 (rank : 1161)
Query Neighborhood Hits	1031	Target Neighborhood Hits	867	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

TESK2_HUMAN
NC score	0.052120 (rank : 867)	θ value	θ > 10 (rank : 1282)
Query Neighborhood Hits	1031	Target Neighborhood Hits	851	Shared Neighborhood Hits	88
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

GUC2E_MOUSE
NC score	0.052089 (rank : 868)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	1031	Target Neighborhood Hits	692	Shared Neighborhood Hits	71
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

ANPRA_MOUSE
NC score	0.052089 (rank : 869)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	1031	Target Neighborhood Hits	600	Shared Neighborhood Hits	69
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

REL_HUMAN
NC score	0.052061 (rank : 870)	θ value	θ > 10 (rank : 1230)
Query Neighborhood Hits	1031	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

ARFG1_MOUSE
NC score	0.052038 (rank : 871)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	1031	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_MOUSE
NC score	0.051965 (rank : 872)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	1031	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

TACC2_HUMAN
NC score	0.051938 (rank : 873)	θ value	θ > 10 (rank : 1272)
Query Neighborhood Hits	1031	Target Neighborhood Hits	856	Shared Neighborhood Hits	159
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

EVL_HUMAN
NC score	0.051903 (rank : 874)	θ value	3.0926 (rank : 756)
Query Neighborhood Hits	1031	Target Neighborhood Hits	260	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

JAG2_MOUSE
NC score	0.051812 (rank : 875)	θ value	θ > 10 (rank : 1152)
Query Neighborhood Hits	1031	Target Neighborhood Hits	504	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

ABI2_HUMAN
NC score	0.051642 (rank : 876)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ARFG1_HUMAN
NC score	0.051608 (rank : 877)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	1031	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

KIT_HUMAN
NC score	0.051590 (rank : 878)	θ value	θ > 10 (rank : 1159)
Query Neighborhood Hits	1031	Target Neighborhood Hits	953	Shared Neighborhood Hits	80
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KSR2_HUMAN
NC score	0.051579 (rank : 879)	θ value	θ > 10 (rank : 1162)
Query Neighborhood Hits	1031	Target Neighborhood Hits	920	Shared Neighborhood Hits	122
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

ARFG3_HUMAN
NC score	0.051469 (rank : 880)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	1031	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

TOPK_HUMAN
NC score	0.051428 (rank : 881)	θ value	θ > 10 (rank : 1294)
Query Neighborhood Hits	1031	Target Neighborhood Hits	605	Shared Neighborhood Hits	65
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

WNK4_MOUSE
NC score	0.051387 (rank : 882)	θ value	1.06291 (rank : 625)
Query Neighborhood Hits	1031	Target Neighborhood Hits	961	Shared Neighborhood Hits	159
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

CENA2_MOUSE
NC score	0.051378 (rank : 883)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	1031	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

RIPK1_MOUSE
NC score	0.051333 (rank : 884)	θ value	θ > 10 (rank : 1237)
Query Neighborhood Hits	1031	Target Neighborhood Hits	874	Shared Neighborhood Hits	89
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

CENA2_HUMAN
NC score	0.051239 (rank : 885)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	1031	Target Neighborhood Hits	83	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

KIT_MOUSE
NC score	0.051218 (rank : 886)	θ value	θ > 10 (rank : 1160)
Query Neighborhood Hits	1031	Target Neighborhood Hits	949	Shared Neighborhood Hits	82
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

BMPR2_MOUSE
NC score	0.051152 (rank : 887)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	1031	Target Neighborhood Hits	738	Shared Neighborhood Hits	77
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

JAK2_HUMAN
NC score	0.051124 (rank : 888)	θ value	θ > 10 (rank : 1155)
Query Neighborhood Hits	1031	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

CRTC1_MOUSE
NC score	0.051039 (rank : 889)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	1031	Target Neighborhood Hits	230	Shared Neighborhood Hits	105
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

BMPR2_HUMAN
NC score	0.051011 (rank : 890)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	1031	Target Neighborhood Hits	736	Shared Neighborhood Hits	74
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

CD2AP_HUMAN
NC score	0.050946 (rank : 891)	θ value	1.81305 (rank : 667)
Query Neighborhood Hits	1031	Target Neighborhood Hits	315	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

FBN1_MOUSE
NC score	0.050928 (rank : 892)	θ value	1.81305 (rank : 672)
Query Neighborhood Hits	1031	Target Neighborhood Hits	563	Shared Neighborhood Hits	59
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

ZDHC5_MOUSE
NC score	0.050842 (rank : 893)	θ value	0.0431538 (rank : 391)
Query Neighborhood Hits	1031	Target Neighborhood Hits	113	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

RELB_MOUSE
NC score	0.050808 (rank : 894)	θ value	θ > 10 (rank : 1229)
Query Neighborhood Hits	1031	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

DNER_MOUSE
NC score	0.050743 (rank : 895)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	1031	Target Neighborhood Hits	413	Shared Neighborhood Hits	36
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

AMOT_HUMAN
NC score	0.050731 (rank : 896)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	1031	Target Neighborhood Hits	712	Shared Neighborhood Hits	155
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

LTB1S_HUMAN
NC score	0.050697 (rank : 897)	θ value	0.163984 (rank : 456)
Query Neighborhood Hits	1031	Target Neighborhood Hits	502	Shared Neighborhood Hits	70
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

RELB_HUMAN
NC score	0.050685 (rank : 898)	θ value	θ > 10 (rank : 1228)
Query Neighborhood Hits	1031	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

DNER_HUMAN
NC score	0.050641 (rank : 899)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	1031	Target Neighborhood Hits	460	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

RU1C_MOUSE
NC score	0.050624 (rank : 900)	θ value	6.88961 (rank : 957)
Query Neighborhood Hits	1031	Target Neighborhood Hits	83	Shared Neighborhood Hits	44
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

JAG2_HUMAN
NC score	0.050494 (rank : 901)	θ value	θ > 10 (rank : 1151)
Query Neighborhood Hits	1031	Target Neighborhood Hits	491	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

SOX13_HUMAN
NC score	0.050461 (rank : 902)	θ value	0.0330416 (rank : 378)
Query Neighborhood Hits	1031	Target Neighborhood Hits	464	Shared Neighborhood Hits	168
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

RU1C_HUMAN
NC score	0.050419 (rank : 903)	θ value	6.88961 (rank : 956)
Query Neighborhood Hits	1031	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

WDR46_MOUSE
NC score	0.050367 (rank : 904)	θ value	0.0961366 (rank : 429)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

LTBP2_HUMAN
NC score	0.050325 (rank : 905)	θ value	θ > 10 (rank : 1171)
Query Neighborhood Hits	1031	Target Neighborhood Hits	552	Shared Neighborhood Hits	71
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TESK1_MOUSE
NC score	0.050297 (rank : 906)	θ value	5.27518 (rank : 902)
Query Neighborhood Hits	1031	Target Neighborhood Hits	862	Shared Neighborhood Hits	108
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TYK2_MOUSE
NC score	0.050258 (rank : 907)	θ value	θ > 10 (rank : 1306)
Query Neighborhood Hits	1031	Target Neighborhood Hits	850	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

WNK1_MOUSE
NC score	0.050252 (rank : 908)	θ value	8.99809 (rank : 1026)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1179	Shared Neighborhood Hits	178
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

SNIP_MOUSE
NC score	0.050246 (rank : 909)	θ value	1.38821 (rank : 656)
Query Neighborhood Hits	1031	Target Neighborhood Hits	319	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

JAG1_HUMAN
NC score	0.050239 (rank : 910)	θ value	θ > 10 (rank : 1149)
Query Neighborhood Hits	1031	Target Neighborhood Hits	514	Shared Neighborhood Hits	33
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAK2_MOUSE
NC score	0.050199 (rank : 911)	θ value	θ > 10 (rank : 1156)
Query Neighborhood Hits	1031	Target Neighborhood Hits	839	Shared Neighborhood Hits	81
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK3_HUMAN
NC score	0.050189 (rank : 912)	θ value	θ > 10 (rank : 1157)
Query Neighborhood Hits	1031	Target Neighborhood Hits	827	Shared Neighborhood Hits	81
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

JAG1_MOUSE
NC score	0.050182 (rank : 913)	θ value	θ > 10 (rank : 1150)
Query Neighborhood Hits	1031	Target Neighborhood Hits	518	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

SPEG_MOUSE
NC score	0.050120 (rank : 914)	θ value	1.81305 (rank : 691)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1959	Shared Neighborhood Hits	376
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

F100B_MOUSE
NC score	0.050008 (rank : 915)	θ value	0.0148317 (rank : 353)
Query Neighborhood Hits	1031	Target Neighborhood Hits	91	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

TS13_MOUSE
NC score	0.049827 (rank : 916)	θ value	3.0926 (rank : 796)
Query Neighborhood Hits	1031	Target Neighborhood Hits	191	Shared Neighborhood Hits	72
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

AP180_HUMAN
NC score	0.049648 (rank : 917)	θ value	1.06291 (rank : 603)
Query Neighborhood Hits	1031	Target Neighborhood Hits	183	Shared Neighborhood Hits	76
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

RANB9_HUMAN
NC score	0.049566 (rank : 918)	θ value	1.38821 (rank : 650)
Query Neighborhood Hits	1031	Target Neighborhood Hits	179	Shared Neighborhood Hits	88
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

EP400_MOUSE
NC score	0.048990 (rank : 919)	θ value	3.0926 (rank : 755)
Query Neighborhood Hits	1031	Target Neighborhood Hits	592	Shared Neighborhood Hits	192
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

MYST3_HUMAN
NC score	0.048656 (rank : 920)	θ value	1.81305 (rank : 684)
Query Neighborhood Hits	1031	Target Neighborhood Hits	772	Shared Neighborhood Hits	157
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

AMPH_MOUSE
NC score	0.048507 (rank : 921)	θ value	3.0926 (rank : 741)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	79
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

3BP1_MOUSE
NC score	0.048458 (rank : 922)	θ value	1.06291 (rank : 600)
Query Neighborhood Hits	1031	Target Neighborhood Hits	238	Shared Neighborhood Hits	90
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

NRX2A_HUMAN
NC score	0.048040 (rank : 923)	θ value	4.03905 (rank : 839)
Query Neighborhood Hits	1031	Target Neighborhood Hits	614	Shared Neighborhood Hits	215
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

CASL_HUMAN
NC score	0.047622 (rank : 924)	θ value	8.99809 (rank : 975)
Query Neighborhood Hits	1031	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

LAMA5_HUMAN
NC score	0.047095 (rank : 925)	θ value	1.81305 (rank : 680)
Query Neighborhood Hits	1031	Target Neighborhood Hits	976	Shared Neighborhood Hits	139
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EP400_HUMAN
NC score	0.046906 (rank : 926)	θ value	8.99809 (rank : 984)
Query Neighborhood Hits	1031	Target Neighborhood Hits	556	Shared Neighborhood Hits	192
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

JIP3_HUMAN
NC score	0.046698 (rank : 927)	θ value	3.0926 (rank : 768)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1039	Shared Neighborhood Hits	209
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

HGS_HUMAN
NC score	0.046636 (rank : 928)	θ value	4.03905 (rank : 828)
Query Neighborhood Hits	1031	Target Neighborhood Hits	517	Shared Neighborhood Hits	124
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

CO3A1_HUMAN
NC score	0.046610 (rank : 929)	θ value	0.47712 (rank : 520)
Query Neighborhood Hits	1031	Target Neighborhood Hits	452	Shared Neighborhood Hits	134
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
NC score	0.046459 (rank : 930)	θ value	0.47712 (rank : 521)
Query Neighborhood Hits	1031	Target Neighborhood Hits	466	Shared Neighborhood Hits	137
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MARK2_HUMAN
NC score	0.046160 (rank : 931)	θ value	3.19293e-05 (rank : 246)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1056	Shared Neighborhood Hits	144
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

CBX2_HUMAN
NC score	0.046142 (rank : 932)	θ value	0.62314 (rank : 539)
Query Neighborhood Hits	1031	Target Neighborhood Hits	264	Shared Neighborhood Hits	87
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

ZDHC8_MOUSE
NC score	0.046108 (rank : 933)	θ value	8.99809 (rank : 1029)
Query Neighborhood Hits	1031	Target Neighborhood Hits	243	Shared Neighborhood Hits	91
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

CNKR2_HUMAN
NC score	0.046101 (rank : 934)	θ value	4.03905 (rank : 814)
Query Neighborhood Hits	1031	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CO4A5_HUMAN
NC score	0.046090 (rank : 935)	θ value	0.813845 (rank : 576)
Query Neighborhood Hits	1031	Target Neighborhood Hits	383	Shared Neighborhood Hits	121
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CNKR2_MOUSE
NC score	0.046077 (rank : 936)	θ value	4.03905 (rank : 815)
Query Neighborhood Hits	1031	Target Neighborhood Hits	197	Shared Neighborhood Hits	34
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

EPN3_MOUSE
NC score	0.045838 (rank : 937)	θ value	5.27518 (rank : 872)
Query Neighborhood Hits	1031	Target Neighborhood Hits	312	Shared Neighborhood Hits	129
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

TACC3_HUMAN
NC score	0.045807 (rank : 938)	θ value	3.0926 (rank : 791)
Query Neighborhood Hits	1031	Target Neighborhood Hits	779	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

SMRC2_HUMAN
NC score	0.045325 (rank : 939)	θ value	5.27518 (rank : 895)
Query Neighborhood Hits	1031	Target Neighborhood Hits	499	Shared Neighborhood Hits	126
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

PRAX_HUMAN
NC score	0.045287 (rank : 940)	θ value	1.06291 (rank : 617)
Query Neighborhood Hits	1031	Target Neighborhood Hits	215	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

SETBP_MOUSE
NC score	0.045226 (rank : 941)	θ value	6.88961 (rank : 959)
Query Neighborhood Hits	1031	Target Neighborhood Hits	352	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

ITSN1_MOUSE
NC score	0.045156 (rank : 942)	θ value	1.81305 (rank : 679)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1669	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

RAI1_MOUSE
NC score	0.045102 (rank : 943)	θ value	6.88961 (rank : 953)
Query Neighborhood Hits	1031	Target Neighborhood Hits	344	Shared Neighborhood Hits	120
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

AAK1_HUMAN
NC score	0.044932 (rank : 944)	θ value	0.47712 (rank : 516)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1077	Shared Neighborhood Hits	211
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ZAR1_MOUSE
NC score	0.044811 (rank : 945)	θ value	1.38821 (rank : 659)
Query Neighborhood Hits	1031	Target Neighborhood Hits	254	Shared Neighborhood Hits	72
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

PER1_HUMAN
NC score	0.044797 (rank : 946)	θ value	5.27518 (rank : 885)
Query Neighborhood Hits	1031	Target Neighborhood Hits	215	Shared Neighborhood Hits	97
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

RTN1_HUMAN
NC score	0.044572 (rank : 947)	θ value	0.21417 (rank : 474)
Query Neighborhood Hits	1031	Target Neighborhood Hits	173	Shared Neighborhood Hits	61
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SMRC2_MOUSE
NC score	0.044386 (rank : 948)	θ value	3.0926 (rank : 787)
Query Neighborhood Hits	1031	Target Neighborhood Hits	487	Shared Neighborhood Hits	123
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

ZDHC5_HUMAN
NC score	0.044131 (rank : 949)	θ value	2.36792 (rank : 740)
Query Neighborhood Hits	1031	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

LRSM1_HUMAN
NC score	0.043656 (rank : 950)	θ value	6.88961 (rank : 941)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1078	Shared Neighborhood Hits	99
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PAK4_MOUSE
NC score	0.043585 (rank : 951)	θ value	0.62314 (rank : 554)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1098	Shared Neighborhood Hits	184
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

SYN2_MOUSE
NC score	0.043512 (rank : 952)	θ value	8.99809 (rank : 1020)
Query Neighborhood Hits	1031	Target Neighborhood Hits	183	Shared Neighborhood Hits	98
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

APC_HUMAN
NC score	0.043334 (rank : 953)	θ value	2.36792 (rank : 697)
Query Neighborhood Hits	1031	Target Neighborhood Hits	603	Shared Neighborhood Hits	123
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

TITIN_HUMAN
NC score	0.043274 (rank : 954)	θ value	0.21417 (rank : 478)
Query Neighborhood Hits	1031	Target Neighborhood Hits	2923	Shared Neighborhood Hits	364
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

BTBDC_HUMAN
NC score	0.043209 (rank : 955)	θ value	5.27518 (rank : 857)
Query Neighborhood Hits	1031	Target Neighborhood Hits	248	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

ITSN1_HUMAN
NC score	0.043042 (rank : 956)	θ value	1.81305 (rank : 678)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1757	Shared Neighborhood Hits	255
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

CD2L7_HUMAN
NC score	0.042873 (rank : 957)	θ value	4.03905 (rank : 811)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1275	Shared Neighborhood Hits	224
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

MK07_HUMAN
NC score	0.042827 (rank : 958)	θ value	3.0926 (rank : 775)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1087	Shared Neighborhood Hits	204
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

AAK1_MOUSE
NC score	0.042678 (rank : 959)	θ value	0.813845 (rank : 571)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1051	Shared Neighborhood Hits	192
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

SYNPO_MOUSE
NC score	0.042579 (rank : 960)	θ value	1.81305 (rank : 693)
Query Neighborhood Hits	1031	Target Neighborhood Hits	242	Shared Neighborhood Hits	103
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SOX13_MOUSE
NC score	0.042531 (rank : 961)	θ value	6.88961 (rank : 962)
Query Neighborhood Hits	1031	Target Neighborhood Hits	495	Shared Neighborhood Hits	168
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

RFIP1_HUMAN
NC score	0.042483 (rank : 962)	θ value	1.06291 (rank : 620)
Query Neighborhood Hits	1031	Target Neighborhood Hits	236	Shared Neighborhood Hits	71
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

MYLK_MOUSE
NC score	0.042303 (rank : 963)	θ value	0.365318 (rank : 504)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1489	Shared Neighborhood Hits	200
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

BRD8_MOUSE
NC score	0.042221 (rank : 964)	θ value	1.38821 (rank : 631)
Query Neighborhood Hits	1031	Target Neighborhood Hits	422	Shared Neighborhood Hits	98
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CCD96_HUMAN
NC score	0.042144 (rank : 965)	θ value	5.27518 (rank : 860)
Query Neighborhood Hits	1031	Target Neighborhood Hits	595	Shared Neighborhood Hits	100
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

GON4L_HUMAN
NC score	0.042095 (rank : 966)	θ value	5.27518 (rank : 875)
Query Neighborhood Hits	1031	Target Neighborhood Hits	555	Shared Neighborhood Hits	130
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HCN2_HUMAN
NC score	0.041808 (rank : 967)	θ value	5.27518 (rank : 876)
Query Neighborhood Hits	1031	Target Neighborhood Hits	369	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

MK07_MOUSE
NC score	0.041275 (rank : 968)	θ value	1.81305 (rank : 683)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1054	Shared Neighborhood Hits	181
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

STAM2_MOUSE
NC score	0.041135 (rank : 969)	θ value	6.88961 (rank : 963)
Query Neighborhood Hits	1031	Target Neighborhood Hits	285	Shared Neighborhood Hits	68
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

CO4A4_HUMAN
NC score	0.041074 (rank : 970)	θ value	0.62314 (rank : 543)
Query Neighborhood Hits	1031	Target Neighborhood Hits	440	Shared Neighborhood Hits	134
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CDAN1_HUMAN
NC score	0.040936 (rank : 971)	θ value	4.03905 (rank : 812)
Query Neighborhood Hits	1031	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

LRSM1_MOUSE
NC score	0.040879 (rank : 972)	θ value	0.47712 (rank : 524)
Query Neighborhood Hits	1031	Target Neighborhood Hits	874	Shared Neighborhood Hits	74
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

COHA1_HUMAN
NC score	0.040643 (rank : 973)	θ value	4.03905 (rank : 816)
Query Neighborhood Hits	1031	Target Neighborhood Hits	400	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

RFIP3_HUMAN
NC score	0.040610 (rank : 974)	θ value	6.88961 (rank : 954)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1055	Shared Neighborhood Hits	152
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

SAMD8_MOUSE
NC score	0.040486 (rank : 975)	θ value	0.0148317 (rank : 354)
Query Neighborhood Hits	1031	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DA37	Gene names	Samd8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

C2TA_HUMAN
NC score	0.040483 (rank : 976)	θ value	0.163984 (rank : 448)
Query Neighborhood Hits	1031	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

SF3B4_HUMAN
NC score	0.040472 (rank : 977)	θ value	0.365318 (rank : 509)
Query Neighborhood Hits	1031	Target Neighborhood Hits	445	Shared Neighborhood Hits	115
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

MYO15_HUMAN
NC score	0.040356 (rank : 978)	θ value	0.125558 (rank : 442)
Query Neighborhood Hits	1031	Target Neighborhood Hits	671	Shared Neighborhood Hits	270
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MAGC1_HUMAN
NC score	0.040326 (rank : 979)	θ value	2.36792 (rank : 722)
Query Neighborhood Hits	1031	Target Neighborhood Hits	431	Shared Neighborhood Hits	147
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

CT055_MOUSE
NC score	0.040115 (rank : 980)	θ value	1.06291 (rank : 606)
Query Neighborhood Hits	1031	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R184, Q8BQE5, Q8K024, Q8VEM7, Q9CU80	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55 homolog.

PDCD7_MOUSE
NC score	0.040112 (rank : 981)	θ value	8.99809 (rank : 1008)
Query Neighborhood Hits	1031	Target Neighborhood Hits	214	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

PER1_MOUSE
NC score	0.040069 (rank : 982)	θ value	0.279714 (rank : 490)
Query Neighborhood Hits	1031	Target Neighborhood Hits	235	Shared Neighborhood Hits	103
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

SRBP1_HUMAN
NC score	0.040011 (rank : 983)	θ value	8.99809 (rank : 1017)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MARK2_MOUSE
NC score	0.039843 (rank : 984)	θ value	1.38821 (rank : 643)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1018	Shared Neighborhood Hits	133
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

RIMB1_MOUSE
NC score	0.039771 (rank : 985)	θ value	8.99809 (rank : 1013)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1376	Shared Neighborhood Hits	212
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

AHI1_HUMAN
NC score	0.039765 (rank : 986)	θ value	0.00228821 (rank : 301)
Query Neighborhood Hits	1031	Target Neighborhood Hits	537	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

RBM16_HUMAN
NC score	0.039697 (rank : 987)	θ value	8.99809 (rank : 1012)
Query Neighborhood Hits	1031	Target Neighborhood Hits	300	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

IER5_MOUSE
NC score	0.039462 (rank : 988)	θ value	2.36792 (rank : 715)
Query Neighborhood Hits	1031	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

HAIR_HUMAN
NC score	0.039442 (rank : 989)	θ value	0.0961366 (rank : 419)
Query Neighborhood Hits	1031	Target Neighborhood Hits	172	Shared Neighborhood Hits	63
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

AMOL1_MOUSE
NC score	0.039379 (rank : 990)	θ value	0.21417 (rank : 466)
Query Neighborhood Hits	1031	Target Neighborhood Hits	445	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

GAK5_HUMAN
NC score	0.039317 (rank : 991)	θ value	2.36792 (rank : 713)
Query Neighborhood Hits	1031	Target Neighborhood Hits	429	Shared Neighborhood Hits	196
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.039240 (rank : 992)	θ value	3.0926 (rank : 763)
Query Neighborhood Hits	1031	Target Neighborhood Hits	415	Shared Neighborhood Hits	191
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PF21B_MOUSE
NC score	0.039104 (rank : 993)	θ value	1.06291 (rank : 614)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	97
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TACC1_MOUSE
NC score	0.039094 (rank : 994)	θ value	4.03905 (rank : 849)
Query Neighborhood Hits	1031	Target Neighborhood Hits	667	Shared Neighborhood Hits	100
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

GAK11_HUMAN
NC score	0.038950 (rank : 995)	θ value	3.0926 (rank : 761)
Query Neighborhood Hits	1031	Target Neighborhood Hits	409	Shared Neighborhood Hits	188
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ARHG6_MOUSE
NC score	0.038842 (rank : 996)	θ value	0.47712 (rank : 517)
Query Neighborhood Hits	1031	Target Neighborhood Hits	394	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

CUTL1_HUMAN
NC score	0.038831 (rank : 997)	θ value	0.365318 (rank : 501)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1574	Shared Neighborhood Hits	198
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GAK6_HUMAN
NC score	0.038691 (rank : 998)	θ value	1.81305 (rank : 675)
Query Neighborhood Hits	1031	Target Neighborhood Hits	392	Shared Neighborhood Hits	189
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MAVS_MOUSE
NC score	0.038690 (rank : 999)	θ value	1.81305 (rank : 682)
Query Neighborhood Hits	1031	Target Neighborhood Hits	170	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

DCC_MOUSE
NC score	0.038644 (rank : 1000)	θ value	0.163984 (rank : 450)
Query Neighborhood Hits	1031	Target Neighborhood Hits	896	Shared Neighborhood Hits	230
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

GAK2_HUMAN
NC score	0.038413 (rank : 1001)	θ value	3.0926 (rank : 762)
Query Neighborhood Hits	1031	Target Neighborhood Hits	406	Shared Neighborhood Hits	186
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ZN318_MOUSE
NC score	0.038327 (rank : 1002)	θ value	1.06291 (rank : 627)
Query Neighborhood Hits	1031	Target Neighborhood Hits	642	Shared Neighborhood Hits	115
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

SMCA4_HUMAN
NC score	0.038195 (rank : 1003)	θ value	0.163984 (rank : 461)
Query Neighborhood Hits	1031	Target Neighborhood Hits	597	Shared Neighborhood Hits	178
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

TXLNA_HUMAN
NC score	0.037897 (rank : 1004)	θ value	0.813845 (rank : 597)
Query Neighborhood Hits	1031	Target Neighborhood Hits	982	Shared Neighborhood Hits	142
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

CO5A1_HUMAN
NC score	0.037889 (rank : 1005)	θ value	3.0926 (rank : 747)
Query Neighborhood Hits	1031	Target Neighborhood Hits	434	Shared Neighborhood Hits	125
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

GRAP_HUMAN
NC score	0.037477 (rank : 1006)	θ value	4.03905 (rank : 826)
Query Neighborhood Hits	1031	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

MAGD4_HUMAN
NC score	0.037333 (rank : 1007)	θ value	0.21417 (rank : 468)
Query Neighborhood Hits	1031	Target Neighborhood Hits	338	Shared Neighborhood Hits	128
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

CBL_MOUSE
NC score	0.037301 (rank : 1008)	θ value	3.0926 (rank : 745)
Query Neighborhood Hits	1031	Target Neighborhood Hits	426	Shared Neighborhood Hits	117
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

IQEC2_MOUSE
NC score	0.037290 (rank : 1009)	θ value	6.88961 (rank : 938)
Query Neighborhood Hits	1031	Target Neighborhood Hits	417	Shared Neighborhood Hits	148
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

CRKL_HUMAN
NC score	0.037089 (rank : 1010)	θ value	0.813845 (rank : 577)
Query Neighborhood Hits	1031	Target Neighborhood Hits	313	Shared Neighborhood Hits	66
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

PO6F2_MOUSE
NC score	0.037036 (rank : 1011)	θ value	3.0926 (rank : 783)
Query Neighborhood Hits	1031	Target Neighborhood Hits	639	Shared Neighborhood Hits	147
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

CAC1G_HUMAN
NC score	0.036967 (rank : 1012)	θ value	0.163984 (rank : 449)
Query Neighborhood Hits	1031	Target Neighborhood Hits	587	Shared Neighborhood Hits	203
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

PO6F2_HUMAN
NC score	0.036802 (rank : 1013)	θ value	0.62314 (rank : 557)
Query Neighborhood Hits	1031	Target Neighborhood Hits	618	Shared Neighborhood Hits	138
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

CRKL_MOUSE
NC score	0.036772 (rank : 1014)	θ value	0.813845 (rank : 578)
Query Neighborhood Hits	1031	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
NC score	0.036604 (rank : 1015)	θ value	5.27518 (rank : 867)
Query Neighborhood Hits	1031	Target Neighborhood Hits	308	Shared Neighborhood Hits	64
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

RUSC2_MOUSE
NC score	0.036511 (rank : 1016)	θ value	8.99809 (rank : 1014)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	110
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

PAK4_HUMAN
NC score	0.036413 (rank : 1017)	θ value	2.36792 (rank : 724)
Query Neighborhood Hits	1031	Target Neighborhood Hits	924	Shared Neighborhood Hits	126
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

MAST3_HUMAN
NC score	0.036371 (rank : 1018)	θ value	0.47712 (rank : 525)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1128	Shared Neighborhood Hits	178
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

ZYX_MOUSE
NC score	0.036354 (rank : 1019)	θ value	5.27518 (rank : 909)
Query Neighborhood Hits	1031	Target Neighborhood Hits	347	Shared Neighborhood Hits	95
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

DEN1A_MOUSE
NC score	0.036188 (rank : 1020)	θ value	0.813845 (rank : 579)
Query Neighborhood Hits	1031	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

BRSK1_HUMAN
NC score	0.036023 (rank : 1021)	θ value	3.0926 (rank : 744)
Query Neighborhood Hits	1031	Target Neighborhood Hits	942	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

ARHG7_HUMAN
NC score	0.035972 (rank : 1022)	θ value	0.47712 (rank : 518)
Query Neighborhood Hits	1031	Target Neighborhood Hits	347	Shared Neighborhood Hits	74
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

TPR_HUMAN
NC score	0.035787 (rank : 1023)	θ value	5.27518 (rank : 903)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1921	Shared Neighborhood Hits	162
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

MAST1_HUMAN
NC score	0.035765 (rank : 1024)	θ value	0.62314 (rank : 550)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1146	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

GR65_HUMAN
NC score	0.035681 (rank : 1025)	θ value	2.36792 (rank : 714)
Query Neighborhood Hits	1031	Target Neighborhood Hits	148	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

IQEC2_HUMAN
NC score	0.035672 (rank : 1026)	θ value	6.88961 (rank : 937)
Query Neighborhood Hits	1031	Target Neighborhood Hits	403	Shared Neighborhood Hits	143
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

PKN3_MOUSE
NC score	0.035544 (rank : 1027)	θ value	0.62314 (rank : 556)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1009	Shared Neighborhood Hits	136
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

CAMKV_HUMAN
NC score	0.035445 (rank : 1028)	θ value	1.38821 (rank : 632)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1084	Shared Neighborhood Hits	180
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

GRAP_MOUSE
NC score	0.035418 (rank : 1029)	θ value	3.0926 (rank : 765)
Query Neighborhood Hits	1031	Target Neighborhood Hits	309	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

ZCH14_MOUSE
NC score	0.035317 (rank : 1030)	θ value	3.0926 (rank : 800)
Query Neighborhood Hits	1031	Target Neighborhood Hits	109	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

CRK_MOUSE
NC score	0.035112 (rank : 1031)	θ value	6.88961 (rank : 924)
Query Neighborhood Hits	1031	Target Neighborhood Hits	314	Shared Neighborhood Hits	67
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CO5A1_MOUSE
NC score	0.035100 (rank : 1032)	θ value	1.81305 (rank : 668)
Query Neighborhood Hits	1031	Target Neighborhood Hits	419	Shared Neighborhood Hits	124
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

STK36_HUMAN
NC score	0.034972 (rank : 1033)	θ value	8.99809 (rank : 1019)
Query Neighborhood Hits	1031	Target Neighborhood Hits	896	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

GAK_HUMAN
NC score	0.034962 (rank : 1034)	θ value	3.0926 (rank : 764)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1028	Shared Neighborhood Hits	160
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GGA3_MOUSE
NC score	0.034961 (rank : 1035)	θ value	0.365318 (rank : 502)
Query Neighborhood Hits	1031	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GAK12_HUMAN
NC score	0.034928 (rank : 1036)	θ value	1.38821 (rank : 639)
Query Neighborhood Hits	1031	Target Neighborhood Hits	374	Shared Neighborhood Hits	168
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

REST_MOUSE
NC score	0.034920 (rank : 1037)	θ value	5.27518 (rank : 888)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1506	Shared Neighborhood Hits	140
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

IQEC3_MOUSE
NC score	0.034898 (rank : 1038)	θ value	4.03905 (rank : 830)
Query Neighborhood Hits	1031	Target Neighborhood Hits	274	Shared Neighborhood Hits	102
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

LIPA3_MOUSE
NC score	0.034700 (rank : 1039)	θ value	4.03905 (rank : 835)
Query Neighborhood Hits	1031	Target Neighborhood Hits	636	Shared Neighborhood Hits	80
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

CCDC6_HUMAN
NC score	0.034670 (rank : 1040)	θ value	6.88961 (rank : 921)
Query Neighborhood Hits	1031	Target Neighborhood Hits	723	Shared Neighborhood Hits	95
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

MAST1_MOUSE
NC score	0.034539 (rank : 1041)	θ value	3.0926 (rank : 771)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1123	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST2_HUMAN
NC score	0.034417 (rank : 1042)	θ value	3.0926 (rank : 772)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1189	Shared Neighborhood Hits	182
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SIN3A_MOUSE
NC score	0.034323 (rank : 1043)	θ value	0.279714 (rank : 491)
Query Neighborhood Hits	1031	Target Neighborhood Hits	169	Shared Neighborhood Hits	72
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

COAA1_HUMAN
NC score	0.034233 (rank : 1044)	θ value	0.62314 (rank : 544)
Query Neighborhood Hits	1031	Target Neighborhood Hits	316	Shared Neighborhood Hits	101
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

HCN4_MOUSE
NC score	0.034206 (rank : 1045)	θ value	0.62314 (rank : 549)
Query Neighborhood Hits	1031	Target Neighborhood Hits	284	Shared Neighborhood Hits	119
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

TP53B_HUMAN
NC score	0.034032 (rank : 1046)	θ value	6.88961 (rank : 965)
Query Neighborhood Hits	1031	Target Neighborhood Hits	413	Shared Neighborhood Hits	79
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

HCN2_MOUSE
NC score	0.033946 (rank : 1047)	θ value	8.99809 (rank : 992)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	131
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

DAAM1_HUMAN
NC score	0.033942 (rank : 1048)	θ value	4.03905 (rank : 819)
Query Neighborhood Hits	1031	Target Neighborhood Hits	483	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

WEE1_MOUSE
NC score	0.033938 (rank : 1049)	θ value	5.27518 (rank : 908)
Query Neighborhood Hits	1031	Target Neighborhood Hits	794	Shared Neighborhood Hits	82
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

AKAP9_HUMAN
NC score	0.033841 (rank : 1050)	θ value	6.88961 (rank : 913)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1710	Shared Neighborhood Hits	143
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

F100B_HUMAN
NC score	0.033600 (rank : 1051)	θ value	0.163984 (rank : 451)
Query Neighborhood Hits	1031	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IYN6	Gene names	FAM100B
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

TGON2_MOUSE
NC score	0.033588 (rank : 1052)	θ value	4.03905 (rank : 851)
Query Neighborhood Hits	1031	Target Neighborhood Hits	277	Shared Neighborhood Hits	65
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

LIPA3_HUMAN
NC score	0.033417 (rank : 1053)	θ value	0.365318 (rank : 503)
Query Neighborhood Hits	1031	Target Neighborhood Hits	828	Shared Neighborhood Hits	99
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

SIN3A_HUMAN
NC score	0.033377 (rank : 1054)	θ value	5.27518 (rank : 894)
Query Neighborhood Hits	1031	Target Neighborhood Hits	180	Shared Neighborhood Hits	89
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

CDT1_HUMAN
NC score	0.033375 (rank : 1055)	θ value	1.38821 (rank : 633)
Query Neighborhood Hits	1031	Target Neighborhood Hits	92	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

NFM_HUMAN
NC score	0.033345 (rank : 1056)	θ value	3.0926 (rank : 781)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1328	Shared Neighborhood Hits	192
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PCX3_MOUSE
NC score	0.033205 (rank : 1057)	θ value	2.36792 (rank : 726)
Query Neighborhood Hits	1031	Target Neighborhood Hits	134	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

HCN4_HUMAN
NC score	0.033018 (rank : 1058)	θ value	1.81305 (rank : 677)
Query Neighborhood Hits	1031	Target Neighborhood Hits	303	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

FXL19_MOUSE
NC score	0.032933 (rank : 1059)	θ value	1.06291 (rank : 608)
Query Neighborhood Hits	1031	Target Neighborhood Hits	217	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

CBL_HUMAN
NC score	0.032881 (rank : 1060)	θ value	0.125558 (rank : 434)
Query Neighborhood Hits	1031	Target Neighborhood Hits	353	Shared Neighborhood Hits	88
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

GA2L1_MOUSE
NC score	0.032830 (rank : 1061)	θ value	1.81305 (rank : 673)
Query Neighborhood Hits	1031	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

ZC3H6_HUMAN
NC score	0.032644 (rank : 1062)	θ value	1.06291 (rank : 626)
Query Neighborhood Hits	1031	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

PDXL2_HUMAN
NC score	0.032376 (rank : 1063)	θ value	0.47712 (rank : 527)
Query Neighborhood Hits	1031	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

ARRD1_MOUSE
NC score	0.032291 (rank : 1064)	θ value	0.365318 (rank : 497)
Query Neighborhood Hits	1031	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ANTR1_MOUSE
NC score	0.032079 (rank : 1065)	θ value	6.88961 (rank : 915)
Query Neighborhood Hits	1031	Target Neighborhood Hits	143	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

FGD1_MOUSE
NC score	0.032031 (rank : 1066)	θ value	0.813845 (rank : 581)
Query Neighborhood Hits	1031	Target Neighborhood Hits	387	Shared Neighborhood Hits	129
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

COBA2_HUMAN
NC score	0.031929 (rank : 1067)	θ value	0.62314 (rank : 545)
Query Neighborhood Hits	1031	Target Neighborhood Hits	408	Shared Neighborhood Hits	108
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

LDB3_MOUSE
NC score	0.031700 (rank : 1068)	θ value	8.99809 (rank : 997)
Query Neighborhood Hits	1031	Target Neighborhood Hits	510	Shared Neighborhood Hits	167
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

CARD6_HUMAN
NC score	0.031621 (rank : 1069)	θ value	4.03905 (rank : 807)
Query Neighborhood Hits	1031	Target Neighborhood Hits	145	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

ZMYM3_HUMAN
NC score	0.031500 (rank : 1070)	θ value	0.813845 (rank : 599)
Query Neighborhood Hits	1031	Target Neighborhood Hits	223	Shared Neighborhood Hits	60
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

TXLNA_MOUSE
NC score	0.031435 (rank : 1071)	θ value	8.99809 (rank : 1023)
Query Neighborhood Hits	1031	Target Neighborhood Hits	846	Shared Neighborhood Hits	94
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

UROL1_MOUSE
NC score	0.031115 (rank : 1072)	θ value	1.81305 (rank : 694)
Query Neighborhood Hits	1031	Target Neighborhood Hits	235	Shared Neighborhood Hits	36
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

DLG5_HUMAN
NC score	0.030884 (rank : 1073)	θ value	3.0926 (rank : 752)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1088	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

SAMD8_HUMAN
NC score	0.030805 (rank : 1074)	θ value	0.62314 (rank : 561)
Query Neighborhood Hits	1031	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q96LT4	Gene names	SAMD8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

PRGC2_MOUSE
NC score	0.030659 (rank : 1075)	θ value	1.06291 (rank : 618)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

YETS2_MOUSE
NC score	0.030348 (rank : 1076)	θ value	8.99809 (rank : 1027)
Query Neighborhood Hits	1031	Target Neighborhood Hits	278	Shared Neighborhood Hits	82
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

DAAM1_MOUSE
NC score	0.030297 (rank : 1077)	θ value	6.88961 (rank : 926)
Query Neighborhood Hits	1031	Target Neighborhood Hits	443	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

PRGC2_HUMAN
NC score	0.029991 (rank : 1078)	θ value	6.88961 (rank : 952)
Query Neighborhood Hits	1031	Target Neighborhood Hits	272	Shared Neighborhood Hits	76
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

IF4B_MOUSE
NC score	0.029975 (rank : 1079)	θ value	2.36792 (rank : 716)
Query Neighborhood Hits	1031	Target Neighborhood Hits	368	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

M4K3_HUMAN
NC score	0.029850 (rank : 1080)	θ value	2.36792 (rank : 721)
Query Neighborhood Hits	1031	Target Neighborhood Hits	857	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IVH8, Q8IVH7, Q9UDM5, Q9Y6R5	Gene names	MAP4K3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK).

GAK10_HUMAN
NC score	0.029793 (rank : 1081)	θ value	3.0926 (rank : 760)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	134
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

FGD1_HUMAN
NC score	0.029623 (rank : 1082)	θ value	8.99809 (rank : 988)
Query Neighborhood Hits	1031	Target Neighborhood Hits	367	Shared Neighborhood Hits	123
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

DAAM2_HUMAN
NC score	0.029570 (rank : 1083)	θ value	4.03905 (rank : 820)
Query Neighborhood Hits	1031	Target Neighborhood Hits	350	Shared Neighborhood Hits	64
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

RP3A_MOUSE
NC score	0.029540 (rank : 1084)	θ value	5.27518 (rank : 890)
Query Neighborhood Hits	1031	Target Neighborhood Hits	510	Shared Neighborhood Hits	163
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

PMYT1_MOUSE
NC score	0.029451 (rank : 1085)	θ value	6.88961 (rank : 950)
Query Neighborhood Hits	1031	Target Neighborhood Hits	910	Shared Neighborhood Hits	131
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

CABL2_MOUSE
NC score	0.029234 (rank : 1086)	θ value	0.62314 (rank : 538)
Query Neighborhood Hits	1031	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

ODO2_MOUSE
NC score	0.029114 (rank : 1087)	θ value	5.27518 (rank : 882)
Query Neighborhood Hits	1031	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

CO8A1_MOUSE
NC score	0.029027 (rank : 1088)	θ value	2.36792 (rank : 701)
Query Neighborhood Hits	1031	Target Neighborhood Hits	251	Shared Neighborhood Hits	78
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

GGA3_HUMAN
NC score	0.028929 (rank : 1089)	θ value	0.62314 (rank : 547)
Query Neighborhood Hits	1031	Target Neighborhood Hits	127	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

CO8A1_HUMAN
NC score	0.028740 (rank : 1090)	θ value	8.99809 (rank : 981)
Query Neighborhood Hits	1031	Target Neighborhood Hits	288	Shared Neighborhood Hits	84
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

TENS4_MOUSE
NC score	0.028698 (rank : 1091)	θ value	2.36792 (rank : 734)
Query Neighborhood Hits	1031	Target Neighborhood Hits	225	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

SEPT9_MOUSE
NC score	0.028415 (rank : 1092)	θ value	0.00869519 (rank : 337)
Query Neighborhood Hits	1031	Target Neighborhood Hits	238	Shared Neighborhood Hits	64
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

CYTSA_HUMAN
NC score	0.028260 (rank : 1093)	θ value	4.03905 (rank : 818)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1138	Shared Neighborhood Hits	127
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CD008_HUMAN
NC score	0.028080 (rank : 1094)	θ value	4.03905 (rank : 808)
Query Neighborhood Hits	1031	Target Neighborhood Hits	330	Shared Neighborhood Hits	76
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

SYNG_MOUSE
NC score	0.027974 (rank : 1095)	θ value	3.0926 (rank : 790)
Query Neighborhood Hits	1031	Target Neighborhood Hits	206	Shared Neighborhood Hits	75
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

E2AK4_HUMAN
NC score	0.027821 (rank : 1096)	θ value	2.36792 (rank : 706)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1012	Shared Neighborhood Hits	100
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

FOXN1_HUMAN
NC score	0.027738 (rank : 1097)	θ value	6.88961 (rank : 933)
Query Neighborhood Hits	1031	Target Neighborhood Hits	377	Shared Neighborhood Hits	142
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

SNRPA_MOUSE
NC score	0.027735 (rank : 1098)	θ value	0.279714 (rank : 493)
Query Neighborhood Hits	1031	Target Neighborhood Hits	129	Shared Neighborhood Hits	25
SwissProt Accessions	Q62189, Q52LA2	Gene names	Snrpa, Rnu1a-1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein A (U1 snRNP protein A) (U1A protein) (U1-A).

CUTL2_MOUSE
NC score	0.027695 (rank : 1099)	θ value	6.88961 (rank : 925)
Query Neighborhood Hits	1031	Target Neighborhood Hits	771	Shared Neighborhood Hits	119
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CEND_MOUSE
NC score	0.027660 (rank : 1100)	θ value	8.99809 (rank : 978)
Query Neighborhood Hits	1031	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JKC6, Q9DBA0	Gene names	Cend1, Bm88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

SNRPA_HUMAN
NC score	0.027557 (rank : 1101)	θ value	0.47712 (rank : 533)
Query Neighborhood Hits	1031	Target Neighborhood Hits	128	Shared Neighborhood Hits	24
SwissProt Accessions	P09012	Gene names	SNRPA
Domain Architecture
Description	U1 small nuclear ribonucleoprotein A (U1 snRNP protein A) (U1A protein) (U1-A).

ADA12_MOUSE
NC score	0.027479 (rank : 1102)	θ value	0.279714 (rank : 482)
Query Neighborhood Hits	1031	Target Neighborhood Hits	474	Shared Neighborhood Hits	156
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

LARP4_HUMAN
NC score	0.027263 (rank : 1103)	θ value	4.03905 (rank : 833)
Query Neighborhood Hits	1031	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

RASF7_MOUSE
NC score	0.027140 (rank : 1104)	θ value	3.0926 (rank : 784)
Query Neighborhood Hits	1031	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DD19	Gene names	Rassf7
Domain Architecture
Description	Ras association domain-containing protein 7.

AHI1_MOUSE
NC score	0.026888 (rank : 1105)	θ value	1.81305 (rank : 663)
Query Neighborhood Hits	1031	Target Neighborhood Hits	496	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ZN687_HUMAN
NC score	0.026677 (rank : 1106)	θ value	0.0961366 (rank : 430)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1244	Shared Neighborhood Hits	264
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

SNPC4_MOUSE
NC score	0.026591 (rank : 1107)	θ value	5.27518 (rank : 896)
Query Neighborhood Hits	1031	Target Neighborhood Hits	237	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

NCK2_HUMAN
NC score	0.026403 (rank : 1108)	θ value	6.88961 (rank : 946)
Query Neighborhood Hits	1031	Target Neighborhood Hits	310	Shared Neighborhood Hits	62
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

CO9A3_HUMAN
NC score	0.026246 (rank : 1109)	θ value	6.88961 (rank : 922)
Query Neighborhood Hits	1031	Target Neighborhood Hits	361	Shared Neighborhood Hits	99
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

GAB1_MOUSE
NC score	0.026116 (rank : 1110)	θ value	1.81305 (rank : 674)
Query Neighborhood Hits	1031	Target Neighborhood Hits	233	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

AFAD_HUMAN
NC score	0.026069 (rank : 1111)	θ value	0.125558 (rank : 431)
Query Neighborhood Hits	1031	Target Neighborhood Hits	689	Shared Neighborhood Hits	89
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PKHG4_HUMAN
NC score	0.026069 (rank : 1112)	θ value	0.62314 (rank : 555)
Query Neighborhood Hits	1031	Target Neighborhood Hits	200	Shared Neighborhood Hits	53
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

SPHK2_HUMAN
NC score	0.025609 (rank : 1113)	θ value	0.47712 (rank : 534)
Query Neighborhood Hits	1031	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

ZCH14_HUMAN
NC score	0.025579 (rank : 1114)	θ value	8.99809 (rank : 1028)
Query Neighborhood Hits	1031	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

SRA1_HUMAN
NC score	0.025455 (rank : 1115)	θ value	4.03905 (rank : 848)
Query Neighborhood Hits	1031	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HD15, Q6NVU9, Q8IXM1, Q9HD13, Q9HD14	Gene names	SRA1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

SEM6C_MOUSE
NC score	0.025318 (rank : 1116)	θ value	0.47712 (rank : 530)
Query Neighborhood Hits	1031	Target Neighborhood Hits	352	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

ZC3H3_MOUSE
NC score	0.025274 (rank : 1117)	θ value	3.0926 (rank : 799)
Query Neighborhood Hits	1031	Target Neighborhood Hits	188	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

WDR33_HUMAN
NC score	0.025125 (rank : 1118)	θ value	2.36792 (rank : 738)
Query Neighborhood Hits	1031	Target Neighborhood Hits	638	Shared Neighborhood Hits	131
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

MYO9B_HUMAN
NC score	0.024934 (rank : 1119)	θ value	3.0926 (rank : 779)
Query Neighborhood Hits	1031	Target Neighborhood Hits	641	Shared Neighborhood Hits	161
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SMAD1_HUMAN
NC score	0.024898 (rank : 1120)	θ value	0.21417 (rank : 475)
Query Neighborhood Hits	1031	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

CTND2_HUMAN
NC score	0.024556 (rank : 1121)	θ value	5.27518 (rank : 868)
Query Neighborhood Hits	1031	Target Neighborhood Hits	333	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PGCB_MOUSE
NC score	0.024342 (rank : 1122)	θ value	0.365318 (rank : 505)
Query Neighborhood Hits	1031	Target Neighborhood Hits	459	Shared Neighborhood Hits	54
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

SI1L3_HUMAN
NC score	0.023899 (rank : 1123)	θ value	4.03905 (rank : 844)
Query Neighborhood Hits	1031	Target Neighborhood Hits	305	Shared Neighborhood Hits	110
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

HDAC9_MOUSE
NC score	0.023873 (rank : 1124)	θ value	1.38821 (rank : 640)
Query Neighborhood Hits	1031	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

TLE1_HUMAN
NC score	0.023792 (rank : 1125)	θ value	0.0563607 (rank : 403)
Query Neighborhood Hits	1031	Target Neighborhood Hits	485	Shared Neighborhood Hits	113
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

SPN90_MOUSE
NC score	0.023612 (rank : 1126)	θ value	5.27518 (rank : 898)
Query Neighborhood Hits	1031	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SMAD1_MOUSE
NC score	0.023448 (rank : 1127)	θ value	0.279714 (rank : 492)
Query Neighborhood Hits	1031	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SMAD5_MOUSE
NC score	0.023015 (rank : 1128)	θ value	0.163984 (rank : 460)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	24
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

FOG1_MOUSE
NC score	0.022987 (rank : 1129)	θ value	2.36792 (rank : 711)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1237	Shared Neighborhood Hits	246
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GBF1_HUMAN
NC score	0.022954 (rank : 1130)	θ value	0.163984 (rank : 452)
Query Neighborhood Hits	1031	Target Neighborhood Hits	142	Shared Neighborhood Hits	46
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

RKHD1_HUMAN
NC score	0.022953 (rank : 1131)	θ value	6.88961 (rank : 955)
Query Neighborhood Hits	1031	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

TLE1_MOUSE
NC score	0.022793 (rank : 1132)	θ value	0.21417 (rank : 479)
Query Neighborhood Hits	1031	Target Neighborhood Hits	491	Shared Neighborhood Hits	112
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

K0423_HUMAN
NC score	0.022547 (rank : 1133)	θ value	8.99809 (rank : 993)
Query Neighborhood Hits	1031	Target Neighborhood Hits	171	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

TIP60_MOUSE
NC score	0.022303 (rank : 1134)	θ value	0.365318 (rank : 511)
Query Neighborhood Hits	1031	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

MOR2A_MOUSE
NC score	0.022225 (rank : 1135)	θ value	6.88961 (rank : 943)
Query Neighborhood Hits	1031	Target Neighborhood Hits	220	Shared Neighborhood Hits	57
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

AIRE_MOUSE
NC score	0.022213 (rank : 1136)	θ value	1.06291 (rank : 601)
Query Neighborhood Hits	1031	Target Neighborhood Hits	196	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

TIP60_HUMAN
NC score	0.022171 (rank : 1137)	θ value	0.47712 (rank : 536)
Query Neighborhood Hits	1031	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

ODO2_HUMAN
NC score	0.022127 (rank : 1138)	θ value	4.03905 (rank : 841)
Query Neighborhood Hits	1031	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	P36957, Q9BQ32	Gene names	DLST, DLTS
Domain Architecture
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

H10_HUMAN
NC score	0.022125 (rank : 1139)	θ value	4.03905 (rank : 827)
Query Neighborhood Hits	1031	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	P07305	Gene names	H1F0, H1FV
Domain Architecture
Description	Histone H1.0 (H1(0)) (Histone H1').

FBX46_MOUSE
NC score	0.021940 (rank : 1140)	θ value	2.36792 (rank : 709)
Query Neighborhood Hits	1031	Target Neighborhood Hits	139	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

ARRD1_HUMAN
NC score	0.021819 (rank : 1141)	θ value	2.36792 (rank : 698)
Query Neighborhood Hits	1031	Target Neighborhood Hits	75	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

ETV5_MOUSE
NC score	0.021778 (rank : 1142)	θ value	4.03905 (rank : 821)
Query Neighborhood Hits	1031	Target Neighborhood Hits	328	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

HXA3_MOUSE
NC score	0.021649 (rank : 1143)	θ value	0.125558 (rank : 439)
Query Neighborhood Hits	1031	Target Neighborhood Hits	558	Shared Neighborhood Hits	134
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

DTD1_MOUSE
NC score	0.021622 (rank : 1144)	θ value	1.38821 (rank : 637)
Query Neighborhood Hits	1031	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DD18, Q9CRE8, Q9CYL0, Q9D013, Q9D1G4	Gene names	Hars2
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

DOCK4_HUMAN
NC score	0.021512 (rank : 1145)	θ value	3.0926 (rank : 753)
Query Neighborhood Hits	1031	Target Neighborhood Hits	237	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

TTP_HUMAN
NC score	0.021490 (rank : 1146)	θ value	0.62314 (rank : 567)
Query Neighborhood Hits	1031	Target Neighborhood Hits	86	Shared Neighborhood Hits	28
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

FOXN1_MOUSE
NC score	0.021388 (rank : 1147)	θ value	3.0926 (rank : 759)
Query Neighborhood Hits	1031	Target Neighborhood Hits	300	Shared Neighborhood Hits	107
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

DMPK_MOUSE
NC score	0.021344 (rank : 1148)	θ value	6.88961 (rank : 928)
Query Neighborhood Hits	1031	Target Neighborhood Hits	908	Shared Neighborhood Hits	88
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

DCC_HUMAN
NC score	0.021139 (rank : 1149)	θ value	1.81305 (rank : 670)
Query Neighborhood Hits	1031	Target Neighborhood Hits	583	Shared Neighborhood Hits	87
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

GGA1_MOUSE
NC score	0.021107 (rank : 1150)	θ value	1.06291 (rank : 609)
Query Neighborhood Hits	1031	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

DTD1_HUMAN
NC score	0.021106 (rank : 1151)	θ value	3.0926 (rank : 754)
Query Neighborhood Hits	1031	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TEA8, Q496D1, Q5W184, Q8WXU8, Q9BW67, Q9H464, Q9H474	Gene names	HARS2, C20orf88
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

AFF3_HUMAN
NC score	0.021022 (rank : 1152)	θ value	4.03905 (rank : 802)
Query Neighborhood Hits	1031	Target Neighborhood Hits	190	Shared Neighborhood Hits	45
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

NTBP1_MOUSE
NC score	0.020996 (rank : 1153)	θ value	8.99809 (rank : 1006)
Query Neighborhood Hits	1031	Target Neighborhood Hits	528	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

MA1B1_HUMAN
NC score	0.020899 (rank : 1154)	θ value	4.03905 (rank : 836)
Query Neighborhood Hits	1031	Target Neighborhood Hits	125	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

RT23_MOUSE
NC score	0.020766 (rank : 1155)	θ value	0.47712 (rank : 529)
Query Neighborhood Hits	1031	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VE22, Q9CXH1	Gene names	Mrps23
Domain Architecture	No domain graphic available
Description	Mitochondrial ribosomal protein S23 (S23mt) (MRP-S23).

DMPK_HUMAN
NC score	0.020571 (rank : 1156)	θ value	6.88961 (rank : 927)
Query Neighborhood Hits	1031	Target Neighborhood Hits	944	Shared Neighborhood Hits	92
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

TNC6B_HUMAN
NC score	0.020535 (rank : 1157)	θ value	3.0926 (rank : 794)
Query Neighborhood Hits	1031	Target Neighborhood Hits	256	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

LPP_MOUSE
NC score	0.020416 (rank : 1158)	θ value	2.36792 (rank : 720)
Query Neighborhood Hits	1031	Target Neighborhood Hits	247	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

SMAD5_HUMAN
NC score	0.020113 (rank : 1159)	θ value	0.163984 (rank : 459)
Query Neighborhood Hits	1031	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

AMOL2_HUMAN
NC score	0.019698 (rank : 1160)	θ value	8.99809 (rank : 971)
Query Neighborhood Hits	1031	Target Neighborhood Hits	603	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

PALB2_MOUSE
NC score	0.019667 (rank : 1161)	θ value	8.99809 (rank : 1007)
Query Neighborhood Hits	1031	Target Neighborhood Hits	133	Shared Neighborhood Hits	36
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

DYN2_MOUSE
NC score	0.019554 (rank : 1162)	θ value	0.0961366 (rank : 418)
Query Neighborhood Hits	1031	Target Neighborhood Hits	104	Shared Neighborhood Hits	29
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN2_HUMAN
NC score	0.019466 (rank : 1163)	θ value	0.813845 (rank : 580)
Query Neighborhood Hits	1031	Target Neighborhood Hits	112	Shared Neighborhood Hits	35
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

CS021_HUMAN
NC score	0.019058 (rank : 1164)	θ value	3.0926 (rank : 749)
Query Neighborhood Hits	1031	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

PO6F1_MOUSE
NC score	0.019030 (rank : 1165)	θ value	3.0926 (rank : 782)
Query Neighborhood Hits	1031	Target Neighborhood Hits	581	Shared Neighborhood Hits	127
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

ZMYM3_MOUSE
NC score	0.018966 (rank : 1166)	θ value	6.88961 (rank : 970)
Query Neighborhood Hits	1031	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

PHF12_HUMAN
NC score	0.018719 (rank : 1167)	θ value	2.36792 (rank : 727)
Query Neighborhood Hits	1031	Target Neighborhood Hits	174	Shared Neighborhood Hits	45
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

TCF7_MOUSE
NC score	0.018616 (rank : 1168)	θ value	5.27518 (rank : 901)
Query Neighborhood Hits	1031	Target Neighborhood Hits	277	Shared Neighborhood Hits	98
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

CCD1A_MOUSE
NC score	0.018246 (rank : 1169)	θ value	0.813845 (rank : 573)
Query Neighborhood Hits	1031	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

ARHG1_MOUSE
NC score	0.018070 (rank : 1170)	θ value	4.03905 (rank : 803)
Query Neighborhood Hits	1031	Target Neighborhood Hits	266	Shared Neighborhood Hits	88
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

TLE4_MOUSE
NC score	0.017805 (rank : 1171)	θ value	3.0926 (rank : 793)
Query Neighborhood Hits	1031	Target Neighborhood Hits	482	Shared Neighborhood Hits	107
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

GP112_HUMAN
NC score	0.017776 (rank : 1172)	θ value	6.88961 (rank : 935)
Query Neighborhood Hits	1031	Target Neighborhood Hits	441	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP152_MOUSE
NC score	0.017724 (rank : 1173)	θ value	0.62314 (rank : 548)
Query Neighborhood Hits	1031	Target Neighborhood Hits	607	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

TLE4_HUMAN
NC score	0.017612 (rank : 1174)	θ value	3.0926 (rank : 792)
Query Neighborhood Hits	1031	Target Neighborhood Hits	477	Shared Neighborhood Hits	107
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

K1914_MOUSE
NC score	0.017504 (rank : 1175)	θ value	8.99809 (rank : 994)
Query Neighborhood Hits	1031	Target Neighborhood Hits	216	Shared Neighborhood Hits	46
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

ESX1L_HUMAN
NC score	0.017495 (rank : 1176)	θ value	0.62314 (rank : 546)
Query Neighborhood Hits	1031	Target Neighborhood Hits	498	Shared Neighborhood Hits	95
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

SEN2_MOUSE
NC score	0.017056 (rank : 1177)	θ value	0.47712 (rank : 531)
Query Neighborhood Hits	1031	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

PRDM2_HUMAN
NC score	0.016868 (rank : 1178)	θ value	2.36792 (rank : 728)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1135	Shared Neighborhood Hits	179
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

AHTF1_MOUSE
NC score	0.016683 (rank : 1179)	θ value	6.88961 (rank : 912)
Query Neighborhood Hits	1031	Target Neighborhood Hits	176	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

PLXB1_MOUSE
NC score	0.016658 (rank : 1180)	θ value	1.38821 (rank : 648)
Query Neighborhood Hits	1031	Target Neighborhood Hits	259	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

ROBO3_HUMAN
NC score	0.016584 (rank : 1181)	θ value	0.62314 (rank : 560)
Query Neighborhood Hits	1031	Target Neighborhood Hits	570	Shared Neighborhood Hits	87
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

TPP2_MOUSE
NC score	0.016142 (rank : 1182)	θ value	2.36792 (rank : 736)
Query Neighborhood Hits	1031	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	Q64514	Gene names	Tpp2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

AKAP6_HUMAN
NC score	0.016118 (rank : 1183)	θ value	5.27518 (rank : 855)
Query Neighborhood Hits	1031	Target Neighborhood Hits	263	Shared Neighborhood Hits	30
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

MYO1F_HUMAN
NC score	0.016045 (rank : 1184)	θ value	4.03905 (rank : 838)
Query Neighborhood Hits	1031	Target Neighborhood Hits	275	Shared Neighborhood Hits	72
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

PHLPP_HUMAN
NC score	0.016031 (rank : 1185)	θ value	6.88961 (rank : 948)
Query Neighborhood Hits	1031	Target Neighborhood Hits	604	Shared Neighborhood Hits	129
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

HXA3_HUMAN
NC score	0.015859 (rank : 1186)	θ value	0.279714 (rank : 487)
Query Neighborhood Hits	1031	Target Neighborhood Hits	535	Shared Neighborhood Hits	118
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

MAGD1_HUMAN
NC score	0.015800 (rank : 1187)	θ value	4.03905 (rank : 837)
Query Neighborhood Hits	1031	Target Neighborhood Hits	130	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

ZFHX2_HUMAN
NC score	0.015757 (rank : 1188)	θ value	6.88961 (rank : 969)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1178	Shared Neighborhood Hits	149
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

REV1_MOUSE
NC score	0.015728 (rank : 1189)	θ value	1.38821 (rank : 654)
Query Neighborhood Hits	1031	Target Neighborhood Hits	67	Shared Neighborhood Hits	22
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

LEG3_MOUSE
NC score	0.015539 (rank : 1190)	θ value	4.03905 (rank : 834)
Query Neighborhood Hits	1031	Target Neighborhood Hits	113	Shared Neighborhood Hits	35
SwissProt Accessions	P16110	Gene names	Lgals3
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-34 galactoside-binding lectin).

SNX18_MOUSE
NC score	0.015215 (rank : 1191)	θ value	5.27518 (rank : 897)
Query Neighborhood Hits	1031	Target Neighborhood Hits	198	Shared Neighborhood Hits	52
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

UBP53_MOUSE
NC score	0.015156 (rank : 1192)	θ value	8.99809 (rank : 1024)
Query Neighborhood Hits	1031	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

FBLI1_MOUSE
NC score	0.015074 (rank : 1193)	θ value	8.99809 (rank : 987)
Query Neighborhood Hits	1031	Target Neighborhood Hits	228	Shared Neighborhood Hits	54
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

TNR3_HUMAN
NC score	0.015051 (rank : 1194)	θ value	0.813845 (rank : 596)
Query Neighborhood Hits	1031	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

FOG1_HUMAN
NC score	0.014996 (rank : 1195)	θ value	2.36792 (rank : 710)
Query Neighborhood Hits	1031	Target Neighborhood Hits	981	Shared Neighborhood Hits	148
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HDAC9_HUMAN
NC score	0.014798 (rank : 1196)	θ value	0.279714 (rank : 486)
Query Neighborhood Hits	1031	Target Neighborhood Hits	201	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

FBLI1_HUMAN
NC score	0.014608 (rank : 1197)	θ value	3.0926 (rank : 757)
Query Neighborhood Hits	1031	Target Neighborhood Hits	200	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

P2RX2_HUMAN
NC score	0.014601 (rank : 1198)	θ value	5.27518 (rank : 883)
Query Neighborhood Hits	1031	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

TPP2_HUMAN
NC score	0.014435 (rank : 1199)	θ value	3.0926 (rank : 795)
Query Neighborhood Hits	1031	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	P29144	Gene names	TPP2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

CE016_HUMAN
NC score	0.014419 (rank : 1200)	θ value	8.99809 (rank : 977)
Query Neighborhood Hits	1031	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

LIMD1_MOUSE
NC score	0.014387 (rank : 1201)	θ value	8.99809 (rank : 998)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

DGCR8_MOUSE
NC score	0.014364 (rank : 1202)	θ value	3.0926 (rank : 751)
Query Neighborhood Hits	1031	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

SEM6B_MOUSE
NC score	0.014284 (rank : 1203)	θ value	1.38821 (rank : 655)
Query Neighborhood Hits	1031	Target Neighborhood Hits	200	Shared Neighborhood Hits	68
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

OTU7A_HUMAN
NC score	0.014191 (rank : 1204)	θ value	0.62314 (rank : 553)
Query Neighborhood Hits	1031	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

DGCR8_HUMAN
NC score	0.014076 (rank : 1205)	θ value	2.36792 (rank : 705)
Query Neighborhood Hits	1031	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

OXRP_HUMAN
NC score	0.013925 (rank : 1206)	θ value	1.81305 (rank : 686)
Query Neighborhood Hits	1031	Target Neighborhood Hits	544	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ZN516_MOUSE
NC score	0.013802 (rank : 1207)	θ value	0.0252991 (rank : 366)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1197	Shared Neighborhood Hits	212
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

BAI1_HUMAN
NC score	0.013558 (rank : 1208)	θ value	4.03905 (rank : 805)
Query Neighborhood Hits	1031	Target Neighborhood Hits	375	Shared Neighborhood Hits	94
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

MEFV_MOUSE
NC score	0.013374 (rank : 1209)	θ value	1.06291 (rank : 613)
Query Neighborhood Hits	1031	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

PRGR_MOUSE
NC score	0.013313 (rank : 1210)	θ value	0.62314 (rank : 558)
Query Neighborhood Hits	1031	Target Neighborhood Hits	286	Shared Neighborhood Hits	81
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

CNTP1_MOUSE
NC score	0.013144 (rank : 1211)	θ value	8.99809 (rank : 980)
Query Neighborhood Hits	1031	Target Neighborhood Hits	183	Shared Neighborhood Hits	34
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

DPOLL_MOUSE
NC score	0.012969 (rank : 1212)	θ value	1.81305 (rank : 671)
Query Neighborhood Hits	1031	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

RING1_MOUSE
NC score	0.012926 (rank : 1213)	θ value	3.0926 (rank : 785)
Query Neighborhood Hits	1031	Target Neighborhood Hits	220	Shared Neighborhood Hits	20
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

KCNH6_HUMAN
NC score	0.012796 (rank : 1214)	θ value	2.36792 (rank : 718)
Query Neighborhood Hits	1031	Target Neighborhood Hits	222	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

PP1R8_HUMAN
NC score	0.012752 (rank : 1215)	θ value	6.88961 (rank : 951)
Query Neighborhood Hits	1031	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q12972, Q5TIF2, Q6PKF6, Q9UBH1, Q9UBZ0	Gene names	PPP1R8, ARD1, NIPP1
Domain Architecture
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)].

FREA_HUMAN
NC score	0.012741 (rank : 1216)	θ value	2.36792 (rank : 712)
Query Neighborhood Hits	1031	Target Neighborhood Hits	205	Shared Neighborhood Hits	75
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

PCOC1_HUMAN
NC score	0.012730 (rank : 1217)	θ value	0.0563607 (rank : 396)
Query Neighborhood Hits	1031	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

VAV3_HUMAN
NC score	0.012670 (rank : 1218)	θ value	5.27518 (rank : 907)
Query Neighborhood Hits	1031	Target Neighborhood Hits	398	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

MORN1_HUMAN
NC score	0.012536 (rank : 1219)	θ value	8.99809 (rank : 1000)
Query Neighborhood Hits	1031	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T089, Q8WW30, Q9H852	Gene names	MORN1
Domain Architecture	No domain graphic available
Description	MORN repeat-containing protein 1.

US6NL_MOUSE
NC score	0.012457 (rank : 1220)	θ value	5.27518 (rank : 905)
Query Neighborhood Hits	1031	Target Neighborhood Hits	157	Shared Neighborhood Hits	43
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

ATS14_HUMAN
NC score	0.012353 (rank : 1221)	θ value	1.06291 (rank : 604)
Query Neighborhood Hits	1031	Target Neighborhood Hits	382	Shared Neighborhood Hits	121
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ADA19_MOUSE
NC score	0.012183 (rank : 1222)	θ value	1.81305 (rank : 662)
Query Neighborhood Hits	1031	Target Neighborhood Hits	315	Shared Neighborhood Hits	55
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

NR4A3_MOUSE
NC score	0.012014 (rank : 1223)	θ value	0.0193708 (rank : 359)
Query Neighborhood Hits	1031	Target Neighborhood Hits	127	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NONO_MOUSE
NC score	0.011862 (rank : 1224)	θ value	2.36792 (rank : 723)
Query Neighborhood Hits	1031	Target Neighborhood Hits	444	Shared Neighborhood Hits	34
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

IRS1_MOUSE
NC score	0.011681 (rank : 1225)	θ value	5.27518 (rank : 878)
Query Neighborhood Hits	1031	Target Neighborhood Hits	112	Shared Neighborhood Hits	33
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

VAV3_MOUSE
NC score	0.011672 (rank : 1226)	θ value	8.99809 (rank : 1025)
Query Neighborhood Hits	1031	Target Neighborhood Hits	404	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

PML_HUMAN
NC score	0.011420 (rank : 1227)	θ value	8.99809 (rank : 1009)
Query Neighborhood Hits	1031	Target Neighborhood Hits	248	Shared Neighborhood Hits	39
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

NET1_HUMAN
NC score	0.011287 (rank : 1228)	θ value	8.99809 (rank : 1004)
Query Neighborhood Hits	1031	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

ZEP1_MOUSE
NC score	0.011165 (rank : 1229)	θ value	0.0148317 (rank : 356)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1063	Shared Neighborhood Hits	141
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

SMAL1_HUMAN
NC score	0.011069 (rank : 1230)	θ value	8.99809 (rank : 1016)
Query Neighborhood Hits	1031	Target Neighborhood Hits	174	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

MGMT_MOUSE
NC score	0.010876 (rank : 1231)	θ value	3.0926 (rank : 773)
Query Neighborhood Hits	1031	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P26187, Q54A49	Gene names	Mgmt
Domain Architecture
Description	Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O- methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA- alkyltransferase).

DAF1_MOUSE
NC score	0.010587 (rank : 1232)	θ value	2.36792 (rank : 703)
Query Neighborhood Hits	1031	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

NONO_HUMAN
NC score	0.010485 (rank : 1233)	θ value	6.88961 (rank : 947)
Query Neighborhood Hits	1031	Target Neighborhood Hits	441	Shared Neighborhood Hits	32
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

DOK1_HUMAN
NC score	0.010387 (rank : 1234)	θ value	6.88961 (rank : 929)
Query Neighborhood Hits	1031	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

KI13B_HUMAN
NC score	0.010301 (rank : 1235)	θ value	5.27518 (rank : 879)
Query Neighborhood Hits	1031	Target Neighborhood Hits	492	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

PP1R8_MOUSE
NC score	0.010293 (rank : 1236)	θ value	8.99809 (rank : 1010)
Query Neighborhood Hits	1031	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

CAC1B_MOUSE
NC score	0.010287 (rank : 1237)	θ value	5.27518 (rank : 859)
Query Neighborhood Hits	1031	Target Neighborhood Hits	351	Shared Neighborhood Hits	90
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

TRRAP_HUMAN
NC score	0.010190 (rank : 1238)	θ value	8.99809 (rank : 1022)
Query Neighborhood Hits	1031	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

CP003_HUMAN
NC score	0.010125 (rank : 1239)	θ value	6.88961 (rank : 923)
Query Neighborhood Hits	1031	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

ETV5_HUMAN
NC score	0.009805 (rank : 1240)	θ value	8.99809 (rank : 986)
Query Neighborhood Hits	1031	Target Neighborhood Hits	181	Shared Neighborhood Hits	59
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

CAR10_MOUSE
NC score	0.009794 (rank : 1241)	θ value	6.88961 (rank : 919)
Query Neighborhood Hits	1031	Target Neighborhood Hits	407	Shared Neighborhood Hits	42
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

SF04_MOUSE
NC score	0.009773 (rank : 1242)	θ value	4.03905 (rank : 843)
Query Neighborhood Hits	1031	Target Neighborhood Hits	95	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CH02, Q8R094	Gene names	Sf4
Domain Architecture	No domain graphic available
Description	Splicing factor 4.

MMP9_HUMAN
NC score	0.009585 (rank : 1243)	θ value	0.813845 (rank : 586)
Query Neighborhood Hits	1031	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

B4GN4_MOUSE
NC score	0.009430 (rank : 1244)	θ value	6.88961 (rank : 917)
Query Neighborhood Hits	1031	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

CU056_HUMAN
NC score	0.009285 (rank : 1245)	θ value	4.03905 (rank : 817)
Query Neighborhood Hits	1031	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0A9, Q9NSE5	Gene names	C21orf56
Domain Architecture	No domain graphic available
Description	Putative protein C21orf56.

GLUD1_MOUSE
NC score	0.009200 (rank : 1246)	θ value	8.99809 (rank : 991)
Query Neighborhood Hits	1031	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

FOXN4_HUMAN
NC score	0.009097 (rank : 1247)	θ value	8.99809 (rank : 989)
Query Neighborhood Hits	1031	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

NR4A3_HUMAN
NC score	0.009006 (rank : 1248)	θ value	0.163984 (rank : 458)
Query Neighborhood Hits	1031	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

PTN22_MOUSE
NC score	0.008988 (rank : 1249)	θ value	2.36792 (rank : 729)
Query Neighborhood Hits	1031	Target Neighborhood Hits	179	Shared Neighborhood Hits	41
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

EST1A_MOUSE
NC score	0.008589 (rank : 1250)	θ value	8.99809 (rank : 985)
Query Neighborhood Hits	1031	Target Neighborhood Hits	138	Shared Neighborhood Hits	21
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

TTC17_HUMAN
NC score	0.008525 (rank : 1251)	θ value	5.27518 (rank : 904)
Query Neighborhood Hits	1031	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q96AE7	Gene names	TTC17
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 17 (TPR repeat protein 17).

ARHGG_MOUSE
NC score	0.008344 (rank : 1252)	θ value	6.88961 (rank : 916)
Query Neighborhood Hits	1031	Target Neighborhood Hits	152	Shared Neighborhood Hits	34
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

MYCN_HUMAN
NC score	0.008247 (rank : 1253)	θ value	6.88961 (rank : 945)
Query Neighborhood Hits	1031	Target Neighborhood Hits	127	Shared Neighborhood Hits	24
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

CQ028_MOUSE
NC score	0.008141 (rank : 1254)	θ value	3.0926 (rank : 748)
Query Neighborhood Hits	1031	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

CF055_HUMAN
NC score	0.008132 (rank : 1255)	θ value	5.27518 (rank : 864)
Query Neighborhood Hits	1031	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP79, Q9H0R2, Q9H3K9, Q9P0Q0	Gene names	C6orf55
Domain Architecture
Description	Protein C6orf55 (Dopamine-responsive protein DRG-1).

FOXO1_MOUSE
NC score	0.007844 (rank : 1256)	θ value	0.47712 (rank : 523)
Query Neighborhood Hits	1031	Target Neighborhood Hits	118	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

STABP_MOUSE
NC score	0.007831 (rank : 1257)	θ value	8.99809 (rank : 1018)
Query Neighborhood Hits	1031	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

UBP8_HUMAN
NC score	0.007641 (rank : 1258)	θ value	4.03905 (rank : 854)
Query Neighborhood Hits	1031	Target Neighborhood Hits	751	Shared Neighborhood Hits	84
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

PKNX2_MOUSE
NC score	0.007633 (rank : 1259)	θ value	1.06291 (rank : 616)
Query Neighborhood Hits	1031	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

K0406_MOUSE
NC score	0.007439 (rank : 1260)	θ value	3.0926 (rank : 769)
Query Neighborhood Hits	1031	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V83, Q9CSY0	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA0406 homolog.

TFE3_HUMAN
NC score	0.007338 (rank : 1261)	θ value	1.38821 (rank : 658)
Query Neighborhood Hits	1031	Target Neighborhood Hits	190	Shared Neighborhood Hits	21
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

FOXO1_HUMAN
NC score	0.007334 (rank : 1262)	θ value	1.38821 (rank : 638)
Query Neighborhood Hits	1031	Target Neighborhood Hits	126	Shared Neighborhood Hits	20
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

PIAS3_MOUSE
NC score	0.007254 (rank : 1263)	θ value	1.06291 (rank : 615)
Query Neighborhood Hits	1031	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	O54714, Q80WF8, Q8R598	Gene names	Pias3
Domain Architecture
Description	Protein inhibitor of activated STAT protein 3.

AUXI_MOUSE
NC score	0.007151 (rank : 1264)	θ value	8.99809 (rank : 974)
Query Neighborhood Hits	1031	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

BOC_HUMAN
NC score	0.007074 (rank : 1265)	θ value	6.88961 (rank : 918)
Query Neighborhood Hits	1031	Target Neighborhood Hits	543	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

PTN14_MOUSE
NC score	0.007015 (rank : 1266)	θ value	0.21417 (rank : 473)
Query Neighborhood Hits	1031	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.006935 (rank : 1267)	θ value	0.365318 (rank : 507)
Query Neighborhood Hits	1031	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

ENV2_MOUSE
NC score	0.006905 (rank : 1268)	θ value	6.88961 (rank : 931)
Query Neighborhood Hits	1031	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

DLG1_HUMAN
NC score	0.006372 (rank : 1269)	θ value	1.38821 (rank : 635)
Query Neighborhood Hits	1031	Target Neighborhood Hits	290	Shared Neighborhood Hits	45
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

SMG5_MOUSE
NC score	0.006292 (rank : 1270)	θ value	6.88961 (rank : 961)
Query Neighborhood Hits	1031	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

C1QC_HUMAN
NC score	0.006191 (rank : 1271)	θ value	5.27518 (rank : 858)
Query Neighborhood Hits	1031	Target Neighborhood Hits	124	Shared Neighborhood Hits	21
SwissProt Accessions	P02747, Q7Z502, Q96DL2, Q96H05	Gene names	C1QC, C1QG
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

B3A3_HUMAN
NC score	0.005962 (rank : 1272)	θ value	4.03905 (rank : 804)
Query Neighborhood Hits	1031	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

MEFV_HUMAN
NC score	0.005925 (rank : 1273)	θ value	0.47712 (rank : 526)
Query Neighborhood Hits	1031	Target Neighborhood Hits	431	Shared Neighborhood Hits	62
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

ALKB3_MOUSE
NC score	0.005765 (rank : 1274)	θ value	5.27518 (rank : 856)
Query Neighborhood Hits	1031	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1E6	Gene names	Alkbh3
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 3.

PCD15_HUMAN
NC score	0.005699 (rank : 1275)	θ value	2.36792 (rank : 725)
Query Neighborhood Hits	1031	Target Neighborhood Hits	289	Shared Neighborhood Hits	64
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

KCNC3_HUMAN
NC score	0.005399 (rank : 1276)	θ value	6.88961 (rank : 939)
Query Neighborhood Hits	1031	Target Neighborhood Hits	256	Shared Neighborhood Hits	78
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

MICA2_HUMAN
NC score	0.005393 (rank : 1277)	θ value	0.62314 (rank : 552)
Query Neighborhood Hits	1031	Target Neighborhood Hits	174	Shared Neighborhood Hits	19
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

PCD15_MOUSE
NC score	0.005354 (rank : 1278)	θ value	0.125558 (rank : 443)
Query Neighborhood Hits	1031	Target Neighborhood Hits	262	Shared Neighborhood Hits	65
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

GCM1_MOUSE
NC score	0.005099 (rank : 1279)	θ value	6.88961 (rank : 934)
Query Neighborhood Hits	1031	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	P70348, O09103	Gene names	Gcm1, Gcma
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (mGCMa) (mGCM1).

HS12B_HUMAN
NC score	0.004899 (rank : 1280)	θ value	3.0926 (rank : 767)
Query Neighborhood Hits	1031	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

ZEP2_MOUSE
NC score	0.004699 (rank : 1281)	θ value	0.163984 (rank : 465)
Query Neighborhood Hits	1031	Target Neighborhood Hits	964	Shared Neighborhood Hits	121
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

E41L3_MOUSE
NC score	0.004598 (rank : 1282)	θ value	5.27518 (rank : 871)
Query Neighborhood Hits	1031	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

SYYC_MOUSE
NC score	0.004537 (rank : 1283)	θ value	8.99809 (rank : 1021)
Query Neighborhood Hits	1031	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183	Gene names	Yars
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

SENP6_HUMAN
NC score	0.004010 (rank : 1284)	θ value	6.88961 (rank : 958)
Query Neighborhood Hits	1031	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

HSPB8_MOUSE
NC score	0.003642 (rank : 1285)	θ value	5.27518 (rank : 877)
Query Neighborhood Hits	1031	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JK92	Gene names	Hspb8, Cryac, Hsp22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22).

RARG1_MOUSE
NC score	0.003204 (rank : 1286)	θ value	1.38821 (rank : 652)
Query Neighborhood Hits	1031	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
NC score	0.003190 (rank : 1287)	θ value	1.38821 (rank : 653)
Query Neighborhood Hits	1031	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

DLG3_MOUSE
NC score	0.002505 (rank : 1288)	θ value	8.99809 (rank : 983)
Query Neighborhood Hits	1031	Target Neighborhood Hits	274	Shared Neighborhood Hits	40
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.002380 (rank : 1289)	θ value	8.99809 (rank : 982)
Query Neighborhood Hits	1031	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

LFNG_HUMAN
NC score	0.002308 (rank : 1290)	θ value	6.88961 (rank : 940)
Query Neighborhood Hits	1031	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NES3, O00589, Q96C39, Q9UJW5	Gene names	LFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

ZN687_MOUSE
NC score	0.002264 (rank : 1291)	θ value	8.99809 (rank : 1031)
Query Neighborhood Hits	1031	Target Neighborhood Hits	913	Shared Neighborhood Hits	126
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ETV7_HUMAN
NC score	0.002207 (rank : 1292)	θ value	2.36792 (rank : 708)
Query Neighborhood Hits	1031	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y603, Q9NZ65, Q9NZ66, Q9NZ68, Q9NZR8, Q9UNJ7, Q9Y5K4, Q9Y604	Gene names	ETV7, TEL2, TELB, TREF
Domain Architecture
Description	Transcription factor ETV7 (Transcription factor Tel-2) (ETS-related protein Tel2) (Tel-related Ets factor).

ACRO_HUMAN
NC score	0.001752 (rank : 1293)	θ value	0.813845 (rank : 572)
Query Neighborhood Hits	1031	Target Neighborhood Hits	291	Shared Neighborhood Hits	75
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

SC6A5_MOUSE
NC score	0.001668 (rank : 1294)	θ value	3.0926 (rank : 786)
Query Neighborhood Hits	1031	Target Neighborhood Hits	135	Shared Neighborhood Hits	40
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

EFCB2_HUMAN
NC score	0.001352 (rank : 1295)	θ value	6.88961 (rank : 930)
Query Neighborhood Hits	1031	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VUJ9, Q59G23, Q9BS36	Gene names	EFCAB2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

ZN438_HUMAN
NC score	0.000718 (rank : 1296)	θ value	0.62314 (rank : 570)
Query Neighborhood Hits	1031	Target Neighborhood Hits	906	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ABCA7_HUMAN
NC score	0.000643 (rank : 1297)	θ value	1.81305 (rank : 661)
Query Neighborhood Hits	1031	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

FOXJ1_HUMAN
NC score	0.000580 (rank : 1298)	θ value	5.27518 (rank : 873)
Query Neighborhood Hits	1031	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q92949, O00630	Gene names	FOXJ1, FKHL13, HFH4
Domain Architecture
Description	Forkhead box protein J1 (Forkhead-related protein FKHL13) (Hepatocyte nuclear factor 3 forkhead homolog 4) (HFH-4).

FOXGB_HUMAN
NC score	0.000487 (rank : 1299)	θ value	6.88961 (rank : 932)
Query Neighborhood Hits	1031	Target Neighborhood Hits	123	Shared Neighborhood Hits	26
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

DDX24_MOUSE
NC score	-0.001195 (rank : 1300)	θ value	2.36792 (rank : 704)
Query Neighborhood Hits	1031	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

CDC20_HUMAN
NC score	-0.002629 (rank : 1301)	θ value	8.99809 (rank : 976)
Query Neighborhood Hits	1031	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

KTNB1_MOUSE
NC score	-0.003545 (rank : 1302)	θ value	3.0926 (rank : 770)
Query Neighborhood Hits	1031	Target Neighborhood Hits	356	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

INSM1_HUMAN
NC score	-0.003753 (rank : 1303)	θ value	1.38821 (rank : 641)
Query Neighborhood Hits	1031	Target Neighborhood Hits	683	Shared Neighborhood Hits	41
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

GLI2_HUMAN
NC score	-0.004279 (rank : 1304)	θ value	4.03905 (rank : 825)
Query Neighborhood Hits	1031	Target Neighborhood Hits	971	Shared Neighborhood Hits	127
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

ZN447_HUMAN
NC score	-0.004524 (rank : 1305)	θ value	1.06291 (rank : 628)
Query Neighborhood Hits	1031	Target Neighborhood Hits	899	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

KCND1_MOUSE
NC score	-0.004622 (rank : 1306)	θ value	8.99809 (rank : 995)
Query Neighborhood Hits	1031	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

HXD1_MOUSE
NC score	-0.004770 (rank : 1307)	θ value	4.03905 (rank : 829)
Query Neighborhood Hits	1031	Target Neighborhood Hits	381	Shared Neighborhood Hits	34
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

KLF17_HUMAN
NC score	-0.004779 (rank : 1308)	θ value	8.99809 (rank : 996)
Query Neighborhood Hits	1031	Target Neighborhood Hits	882	Shared Neighborhood Hits	132
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

MTR1L_HUMAN
NC score	-0.005285 (rank : 1309)	θ value	0.0431538 (rank : 388)
Query Neighborhood Hits	1031	Target Neighborhood Hits	1180	Shared Neighborhood Hits	106
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

ZBTB3_HUMAN
NC score	-0.005980 (rank : 1310)	θ value	2.36792 (rank : 739)
Query Neighborhood Hits	1031	Target Neighborhood Hits	910	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

POGZ_MOUSE
NC score	-0.006029 (rank : 1311)	θ value	0.47712 (rank : 528)
Query Neighborhood Hits	1031	Target Neighborhood Hits	765	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

GLIS3_MOUSE
NC score	-0.008111 (rank : 1312)	θ value	1.06291 (rank : 610)
Query Neighborhood Hits	1031	Target Neighborhood Hits	861	Shared Neighborhood Hits	107
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

DRD4_HUMAN
NC score	-0.008935 (rank : 1313)	θ value	5.27518 (rank : 870)
Query Neighborhood Hits	1031	Target Neighborhood Hits	886	Shared Neighborhood Hits	43
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

ZN341_HUMAN
NC score	-0.009012 (rank : 1314)	θ value	0.0736092 (rank : 415)
Query Neighborhood Hits	1031	Target Neighborhood Hits	803	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

HIC1_HUMAN
NC score	-0.010786 (rank : 1315)	θ value	3.0926 (rank : 766)
Query Neighborhood Hits	1031	Target Neighborhood Hits	838	Shared Neighborhood Hits	58
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

ZN575_HUMAN
NC score	-0.013083 (rank : 1316)	θ value	0.365318 (rank : 515)
Query Neighborhood Hits	1031	Target Neighborhood Hits	739	Shared Neighborhood Hits	43
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

ZN174_HUMAN
NC score	-0.013218 (rank : 1317)	θ value	8.99809 (rank : 1030)
Query Neighborhood Hits	1031	Target Neighborhood Hits	744	Shared Neighborhood Hits	40
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).

GLIS1_MOUSE
NC score	-0.013841 (rank : 1318)	θ value	8.99809 (rank : 990)
Query Neighborhood Hits	1031	Target Neighborhood Hits	751	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

MTR1L_MOUSE
NC score	-0.017580 (rank : 1319)	θ value	8.99809 (rank : 1001)
Query Neighborhood Hits	1031	Target Neighborhood Hits	903	Shared Neighborhood Hits	13
SwissProt Accessions	O88495	Gene names	Gpr50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).