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Network neighborhood for query Sequence : DOCK4_HUMAN

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DOCK4_HUMAN
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DOCK1_HUMAN
θ value	0 (rank : 1)	NC score	0.935049 (rank : 7)
Query Neighborhood Hits	237	Target Neighborhood Hits	191	Shared Neighborhood Hits	35
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DOCK2_HUMAN
θ value	0 (rank : 2)	NC score	0.955163 (rank : 5)
Query Neighborhood Hits	237	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q92608, Q96AK7	Gene names	DOCK2, KIAA0209
Domain Architecture
Description	Dedicator of cytokinesis protein 2.

DOCK2_MOUSE
θ value	0 (rank : 3)	NC score	0.952543 (rank : 6)
Query Neighborhood Hits	237	Target Neighborhood Hits	104	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

DOCK3_HUMAN
θ value	0 (rank : 4)	NC score	0.977561 (rank : 3)
Query Neighborhood Hits	237	Target Neighborhood Hits	87	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
θ value	0 (rank : 5)	NC score	0.976521 (rank : 4)
Query Neighborhood Hits	237	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK4_HUMAN
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	237	Target Neighborhood Hits	237	Shared Neighborhood Hits	237
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	0 (rank : 7)	NC score	0.995033 (rank : 2)
Query Neighborhood Hits	237	Target Neighborhood Hits	210	Shared Neighborhood Hits	179
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOC10_HUMAN
θ value	5.8054e-15 (rank : 8)	NC score	0.457602 (rank : 8)
Query Neighborhood Hits	237	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOCK8_HUMAN
θ value	2.69671e-12 (rank : 9)	NC score	0.411524 (rank : 12)
Query Neighborhood Hits	237	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK9_MOUSE
θ value	3.52202e-12 (rank : 10)	NC score	0.418971 (rank : 10)
Query Neighborhood Hits	237	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_HUMAN
θ value	1.74796e-11 (rank : 11)	NC score	0.415623 (rank : 11)
Query Neighborhood Hits	237	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK8_MOUSE
θ value	2.28291e-11 (rank : 12)	NC score	0.419784 (rank : 9)
Query Neighborhood Hits	237	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK7_HUMAN
θ value	1.47974e-10 (rank : 13)	NC score	0.406137 (rank : 13)
Query Neighborhood Hits	237	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q96N67, Q6ZV32, Q8TB82, Q96NG6, Q9C092	Gene names	DOCK7, KIAA1771
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 7.

DOCK6_HUMAN
θ value	1.25267e-09 (rank : 14)	NC score	0.392253 (rank : 14)
Query Neighborhood Hits	237	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

ACINU_MOUSE
θ value	0.00035302 (rank : 15)	NC score	0.073656 (rank : 25)
Query Neighborhood Hits	237	Target Neighborhood Hits	712	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

DNMBP_HUMAN
θ value	0.00228821 (rank : 16)	NC score	0.110739 (rank : 15)
Query Neighborhood Hits	237	Target Neighborhood Hits	413	Shared Neighborhood Hits	35
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ENL_HUMAN
θ value	0.0193708 (rank : 17)	NC score	0.076704 (rank : 24)
Query Neighborhood Hits	237	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

K1802_MOUSE
θ value	0.0193708 (rank : 18)	NC score	0.054903 (rank : 36)
Query Neighborhood Hits	237	Target Neighborhood Hits	1596	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

DNMBP_MOUSE
θ value	0.0252991 (rank : 19)	NC score	0.104143 (rank : 16)
Query Neighborhood Hits	237	Target Neighborhood Hits	435	Shared Neighborhood Hits	40
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SRRM1_MOUSE
θ value	0.0252991 (rank : 20)	NC score	0.087939 (rank : 19)
Query Neighborhood Hits	237	Target Neighborhood Hits	966	Shared Neighborhood Hits	104
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM1_HUMAN
θ value	0.0330416 (rank : 21)	NC score	0.083377 (rank : 21)
Query Neighborhood Hits	237	Target Neighborhood Hits	690	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ZN292_HUMAN
θ value	0.0330416 (rank : 22)	NC score	0.036748 (rank : 67)
Query Neighborhood Hits	237	Target Neighborhood Hits	918	Shared Neighborhood Hits	24
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

NCOA6_HUMAN
θ value	0.0563607 (rank : 23)	NC score	0.070961 (rank : 26)
Query Neighborhood Hits	237	Target Neighborhood Hits	1202	Shared Neighborhood Hits	108
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PCLO_HUMAN
θ value	0.0563607 (rank : 24)	NC score	0.059076 (rank : 31)
Query Neighborhood Hits	237	Target Neighborhood Hits	2046	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

FREA_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.018500 (rank : 153)
Query Neighborhood Hits	237	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

MUC1_HUMAN
θ value	0.0736092 (rank : 26)	NC score	0.049738 (rank : 40)
Query Neighborhood Hits	237	Target Neighborhood Hits	975	Shared Neighborhood Hits	97
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PO2F2_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.026390 (rank : 116)
Query Neighborhood Hits	237	Target Neighborhood Hits	379	Shared Neighborhood Hits	18
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

NFM_HUMAN
θ value	0.0961366 (rank : 28)	NC score	0.017476 (rank : 156)
Query Neighborhood Hits	237	Target Neighborhood Hits	1328	Shared Neighborhood Hits	75
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SN1L1_HUMAN
θ value	0.0961366 (rank : 29)	NC score	0.007305 (rank : 213)
Query Neighborhood Hits	237	Target Neighborhood Hits	911	Shared Neighborhood Hits	25
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

ST5_MOUSE
θ value	0.0961366 (rank : 30)	NC score	0.031523 (rank : 84)
Query Neighborhood Hits	237	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

LRP10_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.036410 (rank : 68)
Query Neighborhood Hits	237	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

SRBS1_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.087384 (rank : 20)
Query Neighborhood Hits	237	Target Neighborhood Hits	396	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SYNJ1_MOUSE
θ value	0.125558 (rank : 33)	NC score	0.046373 (rank : 46)
Query Neighborhood Hits	237	Target Neighborhood Hits	516	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ZIMP7_MOUSE
θ value	0.125558 (rank : 34)	NC score	0.048075 (rank : 43)
Query Neighborhood Hits	237	Target Neighborhood Hits	566	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

3BP1_HUMAN
θ value	0.163984 (rank : 35)	NC score	0.044874 (rank : 49)
Query Neighborhood Hits	237	Target Neighborhood Hits	376	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GCP6_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.030147 (rank : 90)
Query Neighborhood Hits	237	Target Neighborhood Hits	295	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

NFH_MOUSE
θ value	0.21417 (rank : 37)	NC score	0.039092 (rank : 63)
Query Neighborhood Hits	237	Target Neighborhood Hits	2247	Shared Neighborhood Hits	131
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RAPH1_HUMAN
θ value	0.21417 (rank : 38)	NC score	0.054696 (rank : 37)
Query Neighborhood Hits	237	Target Neighborhood Hits	593	Shared Neighborhood Hits	74
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SELV_HUMAN
θ value	0.21417 (rank : 39)	NC score	0.081165 (rank : 23)
Query Neighborhood Hits	237	Target Neighborhood Hits	118	Shared Neighborhood Hits	30
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

3BP1_MOUSE
θ value	0.279714 (rank : 40)	NC score	0.038905 (rank : 65)
Query Neighborhood Hits	237	Target Neighborhood Hits	238	Shared Neighborhood Hits	32
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ENAM_MOUSE
θ value	0.279714 (rank : 41)	NC score	0.058281 (rank : 32)
Query Neighborhood Hits	237	Target Neighborhood Hits	229	Shared Neighborhood Hits	36
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

HRX_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.044159 (rank : 52)
Query Neighborhood Hits	237	Target Neighborhood Hits	825	Shared Neighborhood Hits	66
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

LRP10_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.034820 (rank : 73)
Query Neighborhood Hits	237	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

PCLO_MOUSE
θ value	0.279714 (rank : 44)	NC score	0.046142 (rank : 47)
Query Neighborhood Hits	237	Target Neighborhood Hits	2275	Shared Neighborhood Hits	129
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MYT1L_HUMAN
θ value	0.365318 (rank : 45)	NC score	0.021159 (rank : 144)
Query Neighborhood Hits	237	Target Neighborhood Hits	471	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

P3C2A_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.016040 (rank : 165)
Query Neighborhood Hits	237	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

PTN23_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.028209 (rank : 104)
Query Neighborhood Hits	237	Target Neighborhood Hits	646	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

BLNK_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.046458 (rank : 45)
Query Neighborhood Hits	237	Target Neighborhood Hits	296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CIC_MOUSE
θ value	0.47712 (rank : 49)	NC score	0.039588 (rank : 61)
Query Neighborhood Hits	237	Target Neighborhood Hits	742	Shared Neighborhood Hits	79
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HEAT1_HUMAN
θ value	0.47712 (rank : 50)	NC score	0.045133 (rank : 48)
Query Neighborhood Hits	237	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

NPAS4_MOUSE
θ value	0.47712 (rank : 51)	NC score	0.030289 (rank : 89)
Query Neighborhood Hits	237	Target Neighborhood Hits	245	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

SRBS1_MOUSE
θ value	0.47712 (rank : 52)	NC score	0.081801 (rank : 22)
Query Neighborhood Hits	237	Target Neighborhood Hits	409	Shared Neighborhood Hits	43
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ARI5B_MOUSE
θ value	0.62314 (rank : 53)	NC score	0.037183 (rank : 66)
Query Neighborhood Hits	237	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

BPA1_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.012579 (rank : 180)
Query Neighborhood Hits	237	Target Neighborhood Hits	1477	Shared Neighborhood Hits	49
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CSKI2_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.025615 (rank : 120)
Query Neighborhood Hits	237	Target Neighborhood Hits	747	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MBD6_HUMAN
θ value	0.62314 (rank : 56)	NC score	0.064999 (rank : 27)
Query Neighborhood Hits	237	Target Neighborhood Hits	349	Shared Neighborhood Hits	51
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.060826 (rank : 29)
Query Neighborhood Hits	237	Target Neighborhood Hits	1446	Shared Neighborhood Hits	117
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MLL3_MOUSE
θ value	0.62314 (rank : 58)	NC score	0.049159 (rank : 41)
Query Neighborhood Hits	237	Target Neighborhood Hits	1399	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NRG2_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.024906 (rank : 123)
Query Neighborhood Hits	237	Target Neighborhood Hits	419	Shared Neighborhood Hits	23
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

SI1L1_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.025571 (rank : 121)
Query Neighborhood Hits	237	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

VINEX_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.090483 (rank : 18)
Query Neighborhood Hits	237	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

AMOT_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.028433 (rank : 103)
Query Neighborhood Hits	237	Target Neighborhood Hits	712	Shared Neighborhood Hits	47
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

LPHN1_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.010002 (rank : 193)
Query Neighborhood Hits	237	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

RIMS1_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.027823 (rank : 108)
Query Neighborhood Hits	237	Target Neighborhood Hits	437	Shared Neighborhood Hits	33
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

VINEX_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.090609 (rank : 17)
Query Neighborhood Hits	237	Target Neighborhood Hits	286	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ZN516_MOUSE
θ value	0.813845 (rank : 66)	NC score	0.007038 (rank : 216)
Query Neighborhood Hits	237	Target Neighborhood Hits	1197	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

DIAP1_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.023678 (rank : 131)
Query Neighborhood Hits	237	Target Neighborhood Hits	784	Shared Neighborhood Hits	44
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DOT1L_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.040342 (rank : 59)
Query Neighborhood Hits	237	Target Neighborhood Hits	660	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

FOXR1_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.020473 (rank : 149)
Query Neighborhood Hits	237	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PIV2, Q86UT9, Q8IXX2	Gene names	FOXR1, DLNB13, FOXN5
Domain Architecture	No domain graphic available
Description	Forkhead box protein R1 (Forkhead box protein N5).

MYT1L_MOUSE
θ value	1.06291 (rank : 70)	NC score	0.026416 (rank : 115)
Query Neighborhood Hits	237	Target Neighborhood Hits	461	Shared Neighborhood Hits	16
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

TENS1_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.030865 (rank : 87)
Query Neighborhood Hits	237	Target Neighborhood Hits	400	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

ZBTB4_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.007072 (rank : 215)
Query Neighborhood Hits	237	Target Neighborhood Hits	926	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

CIC_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.042567 (rank : 54)
Query Neighborhood Hits	237	Target Neighborhood Hits	992	Shared Neighborhood Hits	88
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ012_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.042355 (rank : 57)
Query Neighborhood Hits	237	Target Neighborhood Hits	467	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

DIDO1_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.033341 (rank : 78)
Query Neighborhood Hits	237	Target Neighborhood Hits	960	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ERRFI_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.033309 (rank : 79)
Query Neighborhood Hits	237	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

HCLS1_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.064789 (rank : 28)
Query Neighborhood Hits	237	Target Neighborhood Hits	358	Shared Neighborhood Hits	59
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCN4_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.019492 (rank : 151)
Query Neighborhood Hits	237	Target Neighborhood Hits	284	Shared Neighborhood Hits	36
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HDAC9_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.010279 (rank : 190)
Query Neighborhood Hits	237	Target Neighborhood Hits	201	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

IC1_MOUSE
θ value	1.38821 (rank : 80)	NC score	0.013300 (rank : 179)
Query Neighborhood Hits	237	Target Neighborhood Hits	164	Shared Neighborhood Hits	20
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

M3K10_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.008831 (rank : 202)
Query Neighborhood Hits	237	Target Neighborhood Hits	1071	Shared Neighborhood Hits	41
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

NCOR2_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.029648 (rank : 97)
Query Neighborhood Hits	237	Target Neighborhood Hits	790	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PTPRN_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.013448 (rank : 176)
Query Neighborhood Hits	237	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

SPEG_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.007764 (rank : 207)
Query Neighborhood Hits	237	Target Neighborhood Hits	1762	Shared Neighborhood Hits	82
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPT5H_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.044104 (rank : 53)
Query Neighborhood Hits	237	Target Neighborhood Hits	436	Shared Neighborhood Hits	61
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	1.38821 (rank : 86)	NC score	0.044397 (rank : 51)
Query Neighborhood Hits	237	Target Neighborhood Hits	437	Shared Neighborhood Hits	63
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRRM2_HUMAN
θ value	1.38821 (rank : 87)	NC score	0.053107 (rank : 38)
Query Neighborhood Hits	237	Target Neighborhood Hits	1296	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

AFF3_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.026904 (rank : 114)
Query Neighborhood Hits	237	Target Neighborhood Hits	190	Shared Neighborhood Hits	34
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

BAG3_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.032622 (rank : 81)
Query Neighborhood Hits	237	Target Neighborhood Hits	314	Shared Neighborhood Hits	43
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CAC1D_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.009492 (rank : 197)
Query Neighborhood Hits	237	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CSKI1_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.023944 (rank : 128)
Query Neighborhood Hits	237	Target Neighborhood Hits	997	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MAML3_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.025991 (rank : 117)
Query Neighborhood Hits	237	Target Neighborhood Hits	323	Shared Neighborhood Hits	37
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MISS_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.039232 (rank : 62)
Query Neighborhood Hits	237	Target Neighborhood Hits	444	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL3_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.050537 (rank : 39)
Query Neighborhood Hits	237	Target Neighborhood Hits	1644	Shared Neighborhood Hits	122
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NELFA_MOUSE
θ value	1.81305 (rank : 95)	NC score	0.057075 (rank : 35)
Query Neighborhood Hits	237	Target Neighborhood Hits	195	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

PRG4_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.047766 (rank : 44)
Query Neighborhood Hits	237	Target Neighborhood Hits	764	Shared Neighborhood Hits	87
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RTN4_MOUSE
θ value	1.81305 (rank : 97)	NC score	0.029144 (rank : 101)
Query Neighborhood Hits	237	Target Neighborhood Hits	341	Shared Neighborhood Hits	44
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SYTL2_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.022750 (rank : 134)
Query Neighborhood Hits	237	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TULP1_HUMAN
θ value	1.81305 (rank : 99)	NC score	0.021441 (rank : 142)
Query Neighborhood Hits	237	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

WASF2_MOUSE
θ value	1.81305 (rank : 100)	NC score	0.029894 (rank : 93)
Query Neighborhood Hits	237	Target Neighborhood Hits	315	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ZC3H3_MOUSE
θ value	1.81305 (rank : 101)	NC score	0.027901 (rank : 106)
Query Neighborhood Hits	237	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

B4GN4_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.023097 (rank : 133)
Query Neighborhood Hits	237	Target Neighborhood Hits	131	Shared Neighborhood Hits	19
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

COFA1_MOUSE
θ value	2.36792 (rank : 103)	NC score	0.016963 (rank : 159)
Query Neighborhood Hits	237	Target Neighborhood Hits	305	Shared Neighborhood Hits	24
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CSF1_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.029830 (rank : 94)
Query Neighborhood Hits	237	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

GON4L_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.029592 (rank : 98)
Query Neighborhood Hits	237	Target Neighborhood Hits	455	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

JHD2B_HUMAN
θ value	2.36792 (rank : 106)	NC score	0.024388 (rank : 126)
Query Neighborhood Hits	237	Target Neighborhood Hits	171	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

LYN_MOUSE
θ value	2.36792 (rank : 107)	NC score	0.011532 (rank : 185)
Query Neighborhood Hits	237	Target Neighborhood Hits	1023	Shared Neighborhood Hits	36
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

NACAM_MOUSE
θ value	2.36792 (rank : 108)	NC score	0.058008 (rank : 34)
Query Neighborhood Hits	237	Target Neighborhood Hits	1866	Shared Neighborhood Hits	142
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NPAS1_MOUSE
θ value	2.36792 (rank : 109)	NC score	0.015903 (rank : 166)
Query Neighborhood Hits	237	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

PLXB3_HUMAN
θ value	2.36792 (rank : 110)	NC score	0.007657 (rank : 208)
Query Neighborhood Hits	237	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

RD23A_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.030670 (rank : 88)
Query Neighborhood Hits	237	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	P54725	Gene names	RAD23A
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (hHR23A).

RD23A_MOUSE
θ value	2.36792 (rank : 112)	NC score	0.029122 (rank : 102)
Query Neighborhood Hits	237	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

SON_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.042456 (rank : 55)
Query Neighborhood Hits	237	Target Neighborhood Hits	1568	Shared Neighborhood Hits	123
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ARI4A_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.021983 (rank : 138)
Query Neighborhood Hits	237	Target Neighborhood Hits	434	Shared Neighborhood Hits	14
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CABYR_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.029690 (rank : 96)
Query Neighborhood Hits	237	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CSKI1_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.021512 (rank : 141)
Query Neighborhood Hits	237	Target Neighborhood Hits	1031	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FXL19_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.020675 (rank : 147)
Query Neighborhood Hits	237	Target Neighborhood Hits	217	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

JADE2_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.020646 (rank : 148)
Query Neighborhood Hits	237	Target Neighborhood Hits	560	Shared Neighborhood Hits	64
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

LAD1_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.035653 (rank : 72)
Query Neighborhood Hits	237	Target Neighborhood Hits	441	Shared Neighborhood Hits	56
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MAST4_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.010071 (rank : 192)
Query Neighborhood Hits	237	Target Neighborhood Hits	1804	Shared Neighborhood Hits	98
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NAF1_MOUSE
θ value	3.0926 (rank : 121)	NC score	0.013474 (rank : 175)
Query Neighborhood Hits	237	Target Neighborhood Hits	852	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NCA11_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.013962 (rank : 174)
Query Neighborhood Hits	237	Target Neighborhood Hits	661	Shared Neighborhood Hits	49
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PO2F2_MOUSE
θ value	3.0926 (rank : 123)	NC score	0.014833 (rank : 172)
Query Neighborhood Hits	237	Target Neighborhood Hits	353	Shared Neighborhood Hits	12
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

RFIP1_HUMAN
θ value	3.0926 (rank : 124)	NC score	0.027837 (rank : 107)
Query Neighborhood Hits	237	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RIF1_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.017283 (rank : 158)
Query Neighborhood Hits	237	Target Neighborhood Hits	320	Shared Neighborhood Hits	17
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

SPN90_MOUSE
θ value	3.0926 (rank : 126)	NC score	0.029577 (rank : 99)
Query Neighborhood Hits	237	Target Neighborhood Hits	157	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

TBCD3_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.017512 (rank : 155)
Query Neighborhood Hits	237	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

USH1C_MOUSE
θ value	3.0926 (rank : 128)	NC score	0.017457 (rank : 157)
Query Neighborhood Hits	237	Target Neighborhood Hits	557	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

WIRE_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.044521 (rank : 50)
Query Neighborhood Hits	237	Target Neighborhood Hits	329	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

AB1IP_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.029799 (rank : 95)
Query Neighborhood Hits	237	Target Neighborhood Hits	213	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ANM8_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.013365 (rank : 177)
Query Neighborhood Hits	237	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR22, Q8TBJ8	Gene names	PRMT8, HRMT1L3, HRMT1L4
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4).

CAF1A_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.015344 (rank : 171)
Query Neighborhood Hits	237	Target Neighborhood Hits	750	Shared Neighborhood Hits	31
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CO8A_MOUSE
θ value	4.03905 (rank : 133)	NC score	0.011238 (rank : 186)
Query Neighborhood Hits	237	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

GP158_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.021120 (rank : 145)
Query Neighborhood Hits	237	Target Neighborhood Hits	221	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP1BA_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.009758 (rank : 194)
Query Neighborhood Hits	237	Target Neighborhood Hits	407	Shared Neighborhood Hits	26
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

IRS2_MOUSE
θ value	4.03905 (rank : 136)	NC score	0.023704 (rank : 130)
Query Neighborhood Hits	237	Target Neighborhood Hits	248	Shared Neighborhood Hits	36
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MILK1_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.031071 (rank : 85)
Query Neighborhood Hits	237	Target Neighborhood Hits	788	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINT_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.030087 (rank : 92)
Query Neighborhood Hits	237	Target Neighborhood Hits	1514	Shared Neighborhood Hits	104
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUC2_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.027619 (rank : 111)
Query Neighborhood Hits	237	Target Neighborhood Hits	906	Shared Neighborhood Hits	75
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NKX24_HUMAN
θ value	4.03905 (rank : 140)	NC score	0.002722 (rank : 231)
Query Neighborhood Hits	237	Target Neighborhood Hits	366	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H2Z4	Gene names	NKX2-4, NKX2D
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

OBSCN_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.006607 (rank : 218)
Query Neighborhood Hits	237	Target Neighborhood Hits	1931	Shared Neighborhood Hits	89
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OTU7B_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.010222 (rank : 191)
Query Neighborhood Hits	237	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

PRP8_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.016667 (rank : 162)
Query Neighborhood Hits	237	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P2Q9, O14547, O75965	Gene names	PRPF8, PRPC8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8) (PRP8 homolog) (220 kDa U5 snRNP-specific protein) (p220).

PRP8_MOUSE
θ value	4.03905 (rank : 144)	NC score	0.016670 (rank : 161)
Query Neighborhood Hits	237	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PV0, Q5ND30, Q5ND31, Q7TQK2, Q8BRZ5, Q8K001	Gene names	Prpf8, Prp8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8).

RUSC2_MOUSE
θ value	4.03905 (rank : 145)	NC score	0.025908 (rank : 118)
Query Neighborhood Hits	237	Target Neighborhood Hits	305	Shared Neighborhood Hits	48
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SYEP_HUMAN
θ value	4.03905 (rank : 146)	NC score	0.016356 (rank : 163)
Query Neighborhood Hits	237	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

BLNK_HUMAN
θ value	5.27518 (rank : 147)	NC score	0.025649 (rank : 119)
Query Neighborhood Hits	237	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BTBDC_HUMAN
θ value	5.27518 (rank : 148)	NC score	0.030133 (rank : 91)
Query Neighborhood Hits	237	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CCD45_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.016216 (rank : 164)
Query Neighborhood Hits	237	Target Neighborhood Hits	663	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CT2NL_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.010850 (rank : 188)
Query Neighborhood Hits	237	Target Neighborhood Hits	902	Shared Neighborhood Hits	42
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

GOGA4_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.007323 (rank : 212)
Query Neighborhood Hits	237	Target Neighborhood Hits	2034	Shared Neighborhood Hits	56
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GRIN1_HUMAN
θ value	5.27518 (rank : 152)	NC score	0.034753 (rank : 74)
Query Neighborhood Hits	237	Target Neighborhood Hits	681	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

IF4G3_HUMAN
θ value	5.27518 (rank : 153)	NC score	0.012112 (rank : 181)
Query Neighborhood Hits	237	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

ITSN1_MOUSE
θ value	5.27518 (rank : 154)	NC score	0.040281 (rank : 60)
Query Neighborhood Hits	237	Target Neighborhood Hits	1669	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

K1802_HUMAN
θ value	5.27518 (rank : 155)	NC score	0.034045 (rank : 76)
Query Neighborhood Hits	237	Target Neighborhood Hits	1378	Shared Neighborhood Hits	93
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LYN_HUMAN
θ value	5.27518 (rank : 156)	NC score	0.010683 (rank : 189)
Query Neighborhood Hits	237	Target Neighborhood Hits	1022	Shared Neighborhood Hits	35
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M3K9_HUMAN
θ value	5.27518 (rank : 157)	NC score	0.014482 (rank : 173)
Query Neighborhood Hits	237	Target Neighborhood Hits	1123	Shared Neighborhood Hits	52
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M4K4_HUMAN
θ value	5.27518 (rank : 158)	NC score	0.001940 (rank : 233)
Query Neighborhood Hits	237	Target Neighborhood Hits	1589	Shared Neighborhood Hits	45
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MILK2_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.021046 (rank : 146)
Query Neighborhood Hits	237	Target Neighborhood Hits	457	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

NGEF_MOUSE
θ value	5.27518 (rank : 160)	NC score	0.024178 (rank : 127)
Query Neighborhood Hits	237	Target Neighborhood Hits	228	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

RIN3_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.022407 (rank : 135)
Query Neighborhood Hits	237	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_MOUSE
θ value	5.27518 (rank : 162)	NC score	0.021588 (rank : 140)
Query Neighborhood Hits	237	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ROS_HUMAN
θ value	5.27518 (rank : 163)	NC score	0.000785 (rank : 237)
Query Neighborhood Hits	237	Target Neighborhood Hits	907	Shared Neighborhood Hits	16
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SI1L1_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.015550 (rank : 169)
Query Neighborhood Hits	237	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SRRM2_MOUSE
θ value	5.27518 (rank : 165)	NC score	0.059965 (rank : 30)
Query Neighborhood Hits	237	Target Neighborhood Hits	1470	Shared Neighborhood Hits	128
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TM108_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.031914 (rank : 83)
Query Neighborhood Hits	237	Target Neighborhood Hits	166	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

WIRE_MOUSE
θ value	5.27518 (rank : 167)	NC score	0.041234 (rank : 58)
Query Neighborhood Hits	237	Target Neighborhood Hits	310	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ZIMP7_HUMAN
θ value	5.27518 (rank : 168)	NC score	0.027554 (rank : 112)
Query Neighborhood Hits	237	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ARHGF_HUMAN
θ value	6.88961 (rank : 169)	NC score	0.023247 (rank : 132)
Query Neighborhood Hits	237	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARI1B_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.029167 (rank : 100)
Query Neighborhood Hits	237	Target Neighborhood Hits	567	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

AZI1_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.006848 (rank : 217)
Query Neighborhood Hits	237	Target Neighborhood Hits	1000	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CAF1B_MOUSE
θ value	6.88961 (rank : 172)	NC score	0.010857 (rank : 187)
Query Neighborhood Hits	237	Target Neighborhood Hits	385	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CK024_MOUSE
θ value	6.88961 (rank : 173)	NC score	0.031016 (rank : 86)
Query Neighborhood Hits	237	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CUL4B_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.007766 (rank : 206)
Query Neighborhood Hits	237	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

CUTL2_MOUSE
θ value	6.88961 (rank : 175)	NC score	0.007102 (rank : 214)
Query Neighborhood Hits	237	Target Neighborhood Hits	771	Shared Neighborhood Hits	42
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DPOLQ_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.009572 (rank : 196)
Query Neighborhood Hits	237	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	O75417, O95160	Gene names	POLQ, POLH
Domain Architecture
Description	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta).

ELK1_HUMAN
θ value	6.88961 (rank : 177)	NC score	0.005901 (rank : 220)
Query Neighborhood Hits	237	Target Neighborhood Hits	112	Shared Neighborhood Hits	10
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

EPAS1_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.009445 (rank : 199)
Query Neighborhood Hits	237	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EVI2B_MOUSE
θ value	6.88961 (rank : 179)	NC score	0.015428 (rank : 170)
Query Neighborhood Hits	237	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

FGFP3_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.015658 (rank : 168)
Query Neighborhood Hits	237	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

GON4L_HUMAN
θ value	6.88961 (rank : 181)	NC score	0.021651 (rank : 139)
Query Neighborhood Hits	237	Target Neighborhood Hits	555	Shared Neighborhood Hits	45
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GRAP_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.036171 (rank : 69)
Query Neighborhood Hits	237	Target Neighborhood Hits	307	Shared Neighborhood Hits	32
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	6.88961 (rank : 183)	NC score	0.035834 (rank : 70)
Query Neighborhood Hits	237	Target Neighborhood Hits	309	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

IF35_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.021350 (rank : 143)
Query Neighborhood Hits	237	Target Neighborhood Hits	210	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

ITSN1_HUMAN
θ value	6.88961 (rank : 185)	NC score	0.038998 (rank : 64)
Query Neighborhood Hits	237	Target Neighborhood Hits	1757	Shared Neighborhood Hits	93
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

JAG2_MOUSE
θ value	6.88961 (rank : 186)	NC score	0.001870 (rank : 234)
Query Neighborhood Hits	237	Target Neighborhood Hits	504	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LYAM2_MOUSE
θ value	6.88961 (rank : 187)	NC score	0.003609 (rank : 229)
Query Neighborhood Hits	237	Target Neighborhood Hits	420	Shared Neighborhood Hits	7
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MAMC2_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.011738 (rank : 184)
Query Neighborhood Hits	237	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MBD5_HUMAN
θ value	6.88961 (rank : 189)	NC score	0.028002 (rank : 105)
Query Neighborhood Hits	237	Target Neighborhood Hits	176	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

MYO15_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.011761 (rank : 183)
Query Neighborhood Hits	237	Target Neighborhood Hits	671	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PTN23_MOUSE
θ value	6.88961 (rank : 191)	NC score	0.022367 (rank : 136)
Query Neighborhood Hits	237	Target Neighborhood Hits	726	Shared Neighborhood Hits	68
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SON_MOUSE
θ value	6.88961 (rank : 192)	NC score	0.048188 (rank : 42)
Query Neighborhood Hits	237	Target Neighborhood Hits	957	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SYNJ1_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.033372 (rank : 77)
Query Neighborhood Hits	237	Target Neighborhood Hits	498	Shared Neighborhood Hits	69
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TARA_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.035731 (rank : 71)
Query Neighborhood Hits	237	Target Neighborhood Hits	1626	Shared Neighborhood Hits	107
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TDRD4_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.018376 (rank : 154)
Query Neighborhood Hits	237	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUY9	Gene names	TDRD4
Domain Architecture
Description	Tudor domain-containing protein 4.

TSH2_MOUSE
θ value	6.88961 (rank : 196)	NC score	0.007574 (rank : 210)
Query Neighborhood Hits	237	Target Neighborhood Hits	467	Shared Neighborhood Hits	11
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

TTP_HUMAN
θ value	6.88961 (rank : 197)	NC score	0.018657 (rank : 152)
Query Neighborhood Hits	237	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

TTP_MOUSE
θ value	6.88961 (rank : 198)	NC score	0.013327 (rank : 178)
Query Neighborhood Hits	237	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

WDHD1_HUMAN
θ value	6.88961 (rank : 199)	NC score	0.007819 (rank : 205)
Query Neighborhood Hits	237	Target Neighborhood Hits	342	Shared Neighborhood Hits	11
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

ACTN3_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.005548 (rank : 223)
Query Neighborhood Hits	237	Target Neighborhood Hits	272	Shared Neighborhood Hits	12
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
θ value	8.99809 (rank : 201)	NC score	0.005774 (rank : 222)
Query Neighborhood Hits	237	Target Neighborhood Hits	265	Shared Neighborhood Hits	12
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ANK2_HUMAN
θ value	8.99809 (rank : 202)	NC score	0.022266 (rank : 137)
Query Neighborhood Hits	237	Target Neighborhood Hits	1615	Shared Neighborhood Hits	122
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANM8_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.009636 (rank : 195)
Query Neighborhood Hits	237	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PAK3, Q7M6Z2	Gene names	Prmt8, Hrmt1l4
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4).

BAT2_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.027476 (rank : 113)
Query Neighborhood Hits	237	Target Neighborhood Hits	947	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BPAEA_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.007394 (rank : 211)
Query Neighborhood Hits	237	Target Neighborhood Hits	1369	Shared Neighborhood Hits	42
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BSN_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.042356 (rank : 56)
Query Neighborhood Hits	237	Target Neighborhood Hits	2057	Shared Neighborhood Hits	137
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAC1E_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.005808 (rank : 221)
Query Neighborhood Hits	237	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CN037_MOUSE
θ value	8.99809 (rank : 208)	NC score	0.015783 (rank : 167)
Query Neighborhood Hits	237	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

CRBB3_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.005930 (rank : 219)
Query Neighborhood Hits	237	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJU9	Gene names	Crybb3
Domain Architecture
Description	Beta crystallin B3 (Beta-B3-crystallin).

DAPK1_HUMAN
θ value	8.99809 (rank : 210)	NC score	0.001120 (rank : 235)
Query Neighborhood Hits	237	Target Neighborhood Hits	1130	Shared Neighborhood Hits	20
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_MOUSE
θ value	8.99809 (rank : 211)	NC score	0.001048 (rank : 236)
Query Neighborhood Hits	237	Target Neighborhood Hits	1138	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

GGN_MOUSE
θ value	8.99809 (rank : 212)	NC score	0.032059 (rank : 82)
Query Neighborhood Hits	237	Target Neighborhood Hits	311	Shared Neighborhood Hits	52
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

K1219_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.011851 (rank : 182)
Query Neighborhood Hits	237	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KCNC3_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.005296 (rank : 224)
Query Neighborhood Hits	237	Target Neighborhood Hits	256	Shared Neighborhood Hits	30
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KIRR2_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.004827 (rank : 226)
Query Neighborhood Hits	237	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

LATS1_HUMAN
θ value	8.99809 (rank : 216)	NC score	0.003005 (rank : 230)
Query Neighborhood Hits	237	Target Neighborhood Hits	1057	Shared Neighborhood Hits	42
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

MDC1_MOUSE
θ value	8.99809 (rank : 217)	NC score	0.058103 (rank : 33)
Query Neighborhood Hits	237	Target Neighborhood Hits	998	Shared Neighborhood Hits	104
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MLL2_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.034250 (rank : 75)
Query Neighborhood Hits	237	Target Neighborhood Hits	1788	Shared Neighborhood Hits	106
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL4_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.032833 (rank : 80)
Query Neighborhood Hits	237	Target Neighborhood Hits	722	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MYO15_MOUSE
θ value	8.99809 (rank : 220)	NC score	0.016885 (rank : 160)
Query Neighborhood Hits	237	Target Neighborhood Hits	467	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOR2_HUMAN
θ value	8.99809 (rank : 221)	NC score	0.024683 (rank : 124)
Query Neighborhood Hits	237	Target Neighborhood Hits	870	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NEBU_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.024397 (rank : 125)
Query Neighborhood Hits	237	Target Neighborhood Hits	420	Shared Neighborhood Hits	27
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NMDE3_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.004672 (rank : 227)
Query Neighborhood Hits	237	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NOTC3_MOUSE
θ value	8.99809 (rank : 224)	NC score	0.002221 (rank : 232)
Query Neighborhood Hits	237	Target Neighborhood Hits	975	Shared Neighborhood Hits	36
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PLCB1_HUMAN
θ value	8.99809 (rank : 225)	NC score	0.009471 (rank : 198)
Query Neighborhood Hits	237	Target Neighborhood Hits	614	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB1_MOUSE
θ value	8.99809 (rank : 226)	NC score	0.008727 (rank : 203)
Query Neighborhood Hits	237	Target Neighborhood Hits	531	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLSL_HUMAN
θ value	8.99809 (rank : 227)	NC score	0.005171 (rank : 225)
Query Neighborhood Hits	237	Target Neighborhood Hits	168	Shared Neighborhood Hits	8
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

RGS3_HUMAN
θ value	8.99809 (rank : 228)	NC score	0.023831 (rank : 129)
Query Neighborhood Hits	237	Target Neighborhood Hits	1375	Shared Neighborhood Hits	109
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RPB1_HUMAN
θ value	8.99809 (rank : 229)	NC score	0.027729 (rank : 110)
Query Neighborhood Hits	237	Target Neighborhood Hits	362	Shared Neighborhood Hits	50
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	8.99809 (rank : 230)	NC score	0.027760 (rank : 109)
Query Neighborhood Hits	237	Target Neighborhood Hits	363	Shared Neighborhood Hits	49
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SMP1L_HUMAN
θ value	8.99809 (rank : 231)	NC score	0.009108 (rank : 201)
Query Neighborhood Hits	237	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMRCD_HUMAN
θ value	8.99809 (rank : 232)	NC score	0.003840 (rank : 228)
Query Neighborhood Hits	237	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

TAU_MOUSE
θ value	8.99809 (rank : 233)	NC score	0.025309 (rank : 122)
Query Neighborhood Hits	237	Target Neighborhood Hits	502	Shared Neighborhood Hits	67
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TECT3_MOUSE
θ value	8.99809 (rank : 234)	NC score	0.007626 (rank : 209)
Query Neighborhood Hits	237	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R2Q6, Q8CDF3, Q9CRC5	Gene names	Tect3
Domain Architecture	No domain graphic available
Description	Tectonic-3 precursor.

TITIN_HUMAN
θ value	8.99809 (rank : 235)	NC score	0.009156 (rank : 200)
Query Neighborhood Hits	237	Target Neighborhood Hits	2923	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TMCC1_HUMAN
θ value	8.99809 (rank : 236)	NC score	0.008151 (rank : 204)
Query Neighborhood Hits	237	Target Neighborhood Hits	337	Shared Neighborhood Hits	11
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

WASF3_HUMAN
θ value	8.99809 (rank : 237)	NC score	0.020046 (rank : 150)
Query Neighborhood Hits	237	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

Hits sorted by NC score

DOCK4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	237	Target Neighborhood Hits	237	Shared Neighborhood Hits	237
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
NC score	0.995033 (rank : 2)	θ value	0 (rank : 7)
Query Neighborhood Hits	237	Target Neighborhood Hits	210	Shared Neighborhood Hits	179
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK3_HUMAN
NC score	0.977561 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	237	Target Neighborhood Hits	87	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
NC score	0.976521 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	237	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK2_HUMAN
NC score	0.955163 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	237	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q92608, Q96AK7	Gene names	DOCK2, KIAA0209
Domain Architecture
Description	Dedicator of cytokinesis protein 2.

DOCK2_MOUSE
NC score	0.952543 (rank : 6)	θ value	0 (rank : 3)
Query Neighborhood Hits	237	Target Neighborhood Hits	104	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

DOCK1_HUMAN
NC score	0.935049 (rank : 7)	θ value	0 (rank : 1)
Query Neighborhood Hits	237	Target Neighborhood Hits	191	Shared Neighborhood Hits	35
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DOC10_HUMAN
NC score	0.457602 (rank : 8)	θ value	5.8054e-15 (rank : 8)
Query Neighborhood Hits	237	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOCK8_MOUSE
NC score	0.419784 (rank : 9)	θ value	2.28291e-11 (rank : 12)
Query Neighborhood Hits	237	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK9_MOUSE
NC score	0.418971 (rank : 10)	θ value	3.52202e-12 (rank : 10)
Query Neighborhood Hits	237	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_HUMAN
NC score	0.415623 (rank : 11)	θ value	1.74796e-11 (rank : 11)
Query Neighborhood Hits	237	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK8_HUMAN
NC score	0.411524 (rank : 12)	θ value	2.69671e-12 (rank : 9)
Query Neighborhood Hits	237	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK7_HUMAN
NC score	0.406137 (rank : 13)	θ value	1.47974e-10 (rank : 13)
Query Neighborhood Hits	237	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q96N67, Q6ZV32, Q8TB82, Q96NG6, Q9C092	Gene names	DOCK7, KIAA1771
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 7.

DOCK6_HUMAN
NC score	0.392253 (rank : 14)	θ value	1.25267e-09 (rank : 14)
Query Neighborhood Hits	237	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

DNMBP_HUMAN
NC score	0.110739 (rank : 15)	θ value	0.00228821 (rank : 16)
Query Neighborhood Hits	237	Target Neighborhood Hits	413	Shared Neighborhood Hits	35
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_MOUSE
NC score	0.104143 (rank : 16)	θ value	0.0252991 (rank : 19)
Query Neighborhood Hits	237	Target Neighborhood Hits	435	Shared Neighborhood Hits	40
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

VINEX_MOUSE
NC score	0.090609 (rank : 17)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	237	Target Neighborhood Hits	286	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

VINEX_HUMAN
NC score	0.090483 (rank : 18)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	237	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

SRRM1_MOUSE
NC score	0.087939 (rank : 19)	θ value	0.0252991 (rank : 20)
Query Neighborhood Hits	237	Target Neighborhood Hits	966	Shared Neighborhood Hits	104
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRBS1_HUMAN
NC score	0.087384 (rank : 20)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	237	Target Neighborhood Hits	396	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRRM1_HUMAN
NC score	0.083377 (rank : 21)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	237	Target Neighborhood Hits	690	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRBS1_MOUSE
NC score	0.081801 (rank : 22)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	237	Target Neighborhood Hits	409	Shared Neighborhood Hits	43
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SELV_HUMAN
NC score	0.081165 (rank : 23)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	237	Target Neighborhood Hits	118	Shared Neighborhood Hits	30
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

ENL_HUMAN
NC score	0.076704 (rank : 24)	θ value	0.0193708 (rank : 17)
Query Neighborhood Hits	237	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

ACINU_MOUSE
NC score	0.073656 (rank : 25)	θ value	0.00035302 (rank : 15)
Query Neighborhood Hits	237	Target Neighborhood Hits	712	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NCOA6_HUMAN
NC score	0.070961 (rank : 26)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	237	Target Neighborhood Hits	1202	Shared Neighborhood Hits	108
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MBD6_HUMAN
NC score	0.064999 (rank : 27)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	237	Target Neighborhood Hits	349	Shared Neighborhood Hits	51
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

HCLS1_HUMAN
NC score	0.064789 (rank : 28)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	237	Target Neighborhood Hits	358	Shared Neighborhood Hits	59
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

MDC1_HUMAN
NC score	0.060826 (rank : 29)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	237	Target Neighborhood Hits	1446	Shared Neighborhood Hits	117
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SRRM2_MOUSE
NC score	0.059965 (rank : 30)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	237	Target Neighborhood Hits	1470	Shared Neighborhood Hits	128
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PCLO_HUMAN
NC score	0.059076 (rank : 31)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	237	Target Neighborhood Hits	2046	Shared Neighborhood Hits	118
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ENAM_MOUSE
NC score	0.058281 (rank : 32)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	237	Target Neighborhood Hits	229	Shared Neighborhood Hits	36
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

MDC1_MOUSE
NC score	0.058103 (rank : 33)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	237	Target Neighborhood Hits	998	Shared Neighborhood Hits	104
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NACAM_MOUSE
NC score	0.058008 (rank : 34)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	237	Target Neighborhood Hits	1866	Shared Neighborhood Hits	142
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NELFA_MOUSE
NC score	0.057075 (rank : 35)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	237	Target Neighborhood Hits	195	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

K1802_MOUSE
NC score	0.054903 (rank : 36)	θ value	0.0193708 (rank : 18)
Query Neighborhood Hits	237	Target Neighborhood Hits	1596	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RAPH1_HUMAN
NC score	0.054696 (rank : 37)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	237	Target Neighborhood Hits	593	Shared Neighborhood Hits	74
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SRRM2_HUMAN
NC score	0.053107 (rank : 38)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	237	Target Neighborhood Hits	1296	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MLL3_HUMAN
NC score	0.050537 (rank : 39)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	237	Target Neighborhood Hits	1644	Shared Neighborhood Hits	122
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MUC1_HUMAN
NC score	0.049738 (rank : 40)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	237	Target Neighborhood Hits	975	Shared Neighborhood Hits	97
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MLL3_MOUSE
NC score	0.049159 (rank : 41)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	237	Target Neighborhood Hits	1399	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SON_MOUSE
NC score	0.048188 (rank : 42)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	237	Target Neighborhood Hits	957	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ZIMP7_MOUSE
NC score	0.048075 (rank : 43)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	237	Target Neighborhood Hits	566	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

PRG4_HUMAN
NC score	0.047766 (rank : 44)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	237	Target Neighborhood Hits	764	Shared Neighborhood Hits	87
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

BLNK_MOUSE
NC score	0.046458 (rank : 45)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	237	Target Neighborhood Hits	296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

SYNJ1_MOUSE
NC score	0.046373 (rank : 46)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	237	Target Neighborhood Hits	516	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PCLO_MOUSE
NC score	0.046142 (rank : 47)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	237	Target Neighborhood Hits	2275	Shared Neighborhood Hits	129
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

HEAT1_HUMAN
NC score	0.045133 (rank : 48)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	237	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

3BP1_HUMAN
NC score	0.044874 (rank : 49)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	237	Target Neighborhood Hits	376	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

WIRE_HUMAN
NC score	0.044521 (rank : 50)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	237	Target Neighborhood Hits	329	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

SPT5H_MOUSE
NC score	0.044397 (rank : 51)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	237	Target Neighborhood Hits	437	Shared Neighborhood Hits	63
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

HRX_HUMAN
NC score	0.044159 (rank : 52)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	237	Target Neighborhood Hits	825	Shared Neighborhood Hits	66
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SPT5H_HUMAN
NC score	0.044104 (rank : 53)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	237	Target Neighborhood Hits	436	Shared Neighborhood Hits	61
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

CIC_HUMAN
NC score	0.042567 (rank : 54)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	237	Target Neighborhood Hits	992	Shared Neighborhood Hits	88
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SON_HUMAN
NC score	0.042456 (rank : 55)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	237	Target Neighborhood Hits	1568	Shared Neighborhood Hits	123
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BSN_MOUSE
NC score	0.042356 (rank : 56)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	237	Target Neighborhood Hits	2057	Shared Neighborhood Hits	137
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CJ012_HUMAN
NC score	0.042355 (rank : 57)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	237	Target Neighborhood Hits	467	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

WIRE_MOUSE
NC score	0.041234 (rank : 58)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	237	Target Neighborhood Hits	310	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

DOT1L_HUMAN
NC score	0.040342 (rank : 59)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	237	Target Neighborhood Hits	660	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

ITSN1_MOUSE
NC score	0.040281 (rank : 60)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	237	Target Neighborhood Hits	1669	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

CIC_MOUSE
NC score	0.039588 (rank : 61)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	237	Target Neighborhood Hits	742	Shared Neighborhood Hits	79
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MISS_MOUSE
NC score	0.039232 (rank : 62)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	237	Target Neighborhood Hits	444	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

NFH_MOUSE
NC score	0.039092 (rank : 63)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	237	Target Neighborhood Hits	2247	Shared Neighborhood Hits	131
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ITSN1_HUMAN
NC score	0.038998 (rank : 64)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	237	Target Neighborhood Hits	1757	Shared Neighborhood Hits	93
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

3BP1_MOUSE
NC score	0.038905 (rank : 65)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	237	Target Neighborhood Hits	238	Shared Neighborhood Hits	32
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ARI5B_MOUSE
NC score	0.037183 (rank : 66)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	237	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

ZN292_HUMAN
NC score	0.036748 (rank : 67)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	237	Target Neighborhood Hits	918	Shared Neighborhood Hits	24
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

LRP10_MOUSE
NC score	0.036410 (rank : 68)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	237	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

GRAP_HUMAN
NC score	0.036171 (rank : 69)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	237	Target Neighborhood Hits	307	Shared Neighborhood Hits	32
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
NC score	0.035834 (rank : 70)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	237	Target Neighborhood Hits	309	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

TARA_HUMAN
NC score	0.035731 (rank : 71)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	237	Target Neighborhood Hits	1626	Shared Neighborhood Hits	107
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LAD1_HUMAN
NC score	0.035653 (rank : 72)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	237	Target Neighborhood Hits	441	Shared Neighborhood Hits	56
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LRP10_HUMAN
NC score	0.034820 (rank : 73)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	237	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

GRIN1_HUMAN
NC score	0.034753 (rank : 74)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	237	Target Neighborhood Hits	681	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MLL2_HUMAN
NC score	0.034250 (rank : 75)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	237	Target Neighborhood Hits	1788	Shared Neighborhood Hits	106
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

K1802_HUMAN
NC score	0.034045 (rank : 76)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	237	Target Neighborhood Hits	1378	Shared Neighborhood Hits	93
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SYNJ1_HUMAN
NC score	0.033372 (rank : 77)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	237	Target Neighborhood Hits	498	Shared Neighborhood Hits	69
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

DIDO1_HUMAN
NC score	0.033341 (rank : 78)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	237	Target Neighborhood Hits	960	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ERRFI_HUMAN
NC score	0.033309 (rank : 79)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	237	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

MLL4_HUMAN
NC score	0.032833 (rank : 80)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	237	Target Neighborhood Hits	722	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

BAG3_HUMAN
NC score	0.032622 (rank : 81)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	237	Target Neighborhood Hits	314	Shared Neighborhood Hits	43
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

GGN_MOUSE
NC score	0.032059 (rank : 82)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	237	Target Neighborhood Hits	311	Shared Neighborhood Hits	52
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

TM108_HUMAN
NC score	0.031914 (rank : 83)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	237	Target Neighborhood Hits	166	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ST5_MOUSE
NC score	0.031523 (rank : 84)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	237	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

MILK1_MOUSE
NC score	0.031071 (rank : 85)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	237	Target Neighborhood Hits	788	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CK024_MOUSE
NC score	0.031016 (rank : 86)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	237	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

TENS1_HUMAN
NC score	0.030865 (rank : 87)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	237	Target Neighborhood Hits	400	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

RD23A_HUMAN
NC score	0.030670 (rank : 88)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	237	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	P54725	Gene names	RAD23A
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (hHR23A).

NPAS4_MOUSE
NC score	0.030289 (rank : 89)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	237	Target Neighborhood Hits	245	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

GCP6_HUMAN
NC score	0.030147 (rank : 90)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	237	Target Neighborhood Hits	295	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

BTBDC_HUMAN
NC score	0.030133 (rank : 91)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	237	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

MINT_MOUSE
NC score	0.030087 (rank : 92)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	237	Target Neighborhood Hits	1514	Shared Neighborhood Hits	104
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

WASF2_MOUSE
NC score	0.029894 (rank : 93)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	237	Target Neighborhood Hits	315	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

CSF1_HUMAN
NC score	0.029830 (rank : 94)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	237	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

AB1IP_HUMAN
NC score	0.029799 (rank : 95)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	237	Target Neighborhood Hits	213	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

CABYR_MOUSE
NC score	0.029690 (rank : 96)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	237	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

NCOR2_MOUSE
NC score	0.029648 (rank : 97)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	237	Target Neighborhood Hits	790	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

GON4L_MOUSE
NC score	0.029592 (rank : 98)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	237	Target Neighborhood Hits	455	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SPN90_MOUSE
NC score	0.029577 (rank : 99)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	237	Target Neighborhood Hits	157	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

ARI1B_HUMAN
NC score	0.029167 (rank : 100)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	237	Target Neighborhood Hits	567	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

RTN4_MOUSE
NC score	0.029144 (rank : 101)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	237	Target Neighborhood Hits	341	Shared Neighborhood Hits	44
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

RD23A_MOUSE
NC score	0.029122 (rank : 102)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	237	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

AMOT_HUMAN
NC score	0.028433 (rank : 103)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	237	Target Neighborhood Hits	712	Shared Neighborhood Hits	47
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

PTN23_HUMAN
NC score	0.028209 (rank : 104)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	237	Target Neighborhood Hits	646	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

MBD5_HUMAN
NC score	0.028002 (rank : 105)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	237	Target Neighborhood Hits	176	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

ZC3H3_MOUSE
NC score	0.027901 (rank : 106)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	237	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

RFIP1_HUMAN
NC score	0.027837 (rank : 107)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	237	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RIMS1_HUMAN
NC score	0.027823 (rank : 108)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	237	Target Neighborhood Hits	437	Shared Neighborhood Hits	33
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RPB1_MOUSE
NC score	0.027760 (rank : 109)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	237	Target Neighborhood Hits	363	Shared Neighborhood Hits	49
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.027729 (rank : 110)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	237	Target Neighborhood Hits	362	Shared Neighborhood Hits	50
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

MUC2_HUMAN
NC score	0.027619 (rank : 111)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	237	Target Neighborhood Hits	906	Shared Neighborhood Hits	75
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ZIMP7_HUMAN
NC score	0.027554 (rank : 112)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	237	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

BAT2_MOUSE
NC score	0.027476 (rank : 113)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	237	Target Neighborhood Hits	947	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

AFF3_HUMAN
NC score	0.026904 (rank : 114)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	237	Target Neighborhood Hits	190	Shared Neighborhood Hits	34
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

MYT1L_MOUSE
NC score	0.026416 (rank : 115)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	237	Target Neighborhood Hits	461	Shared Neighborhood Hits	16
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

PO2F2_HUMAN
NC score	0.026390 (rank : 116)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	237	Target Neighborhood Hits	379	Shared Neighborhood Hits	18
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

MAML3_HUMAN
NC score	0.025991 (rank : 117)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	237	Target Neighborhood Hits	323	Shared Neighborhood Hits	37
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

RUSC2_MOUSE
NC score	0.025908 (rank : 118)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	237	Target Neighborhood Hits	305	Shared Neighborhood Hits	48
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

BLNK_HUMAN
NC score	0.025649 (rank : 119)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	237	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

CSKI2_HUMAN
NC score	0.025615 (rank : 120)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	237	Target Neighborhood Hits	747	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

SI1L1_MOUSE
NC score	0.025571 (rank : 121)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	237	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

TAU_MOUSE
NC score	0.025309 (rank : 122)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	237	Target Neighborhood Hits	502	Shared Neighborhood Hits	67
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

NRG2_HUMAN
NC score	0.024906 (rank : 123)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	237	Target Neighborhood Hits	419	Shared Neighborhood Hits	23
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NCOR2_HUMAN
NC score	0.024683 (rank : 124)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	237	Target Neighborhood Hits	870	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NEBU_HUMAN
NC score	0.024397 (rank : 125)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	237	Target Neighborhood Hits	420	Shared Neighborhood Hits	27
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

JHD2B_HUMAN
NC score	0.024388 (rank : 126)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	237	Target Neighborhood Hits	171	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

NGEF_MOUSE
NC score	0.024178 (rank : 127)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	237	Target Neighborhood Hits	228	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

CSKI1_HUMAN
NC score	0.023944 (rank : 128)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	237	Target Neighborhood Hits	997	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

RGS3_HUMAN
NC score	0.023831 (rank : 129)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	237	Target Neighborhood Hits	1375	Shared Neighborhood Hits	109
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

IRS2_MOUSE
NC score	0.023704 (rank : 130)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	237	Target Neighborhood Hits	248	Shared Neighborhood Hits	36
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

DIAP1_HUMAN
NC score	0.023678 (rank : 131)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	237	Target Neighborhood Hits	784	Shared Neighborhood Hits	44
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

ARHGF_HUMAN
NC score	0.023247 (rank : 132)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	237	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

B4GN4_HUMAN
NC score	0.023097 (rank : 133)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	237	Target Neighborhood Hits	131	Shared Neighborhood Hits	19
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

SYTL2_HUMAN
NC score	0.022750 (rank : 134)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	237	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

RIN3_HUMAN
NC score	0.022407 (rank : 135)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	237	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

PTN23_MOUSE
NC score	0.022367 (rank : 136)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	237	Target Neighborhood Hits	726	Shared Neighborhood Hits	68
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

ANK2_HUMAN
NC score	0.022266 (rank : 137)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	237	Target Neighborhood Hits	1615	Shared Neighborhood Hits	122
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ARI4A_HUMAN
NC score	0.021983 (rank : 138)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	237	Target Neighborhood Hits	434	Shared Neighborhood Hits	14
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

GON4L_HUMAN
NC score	0.021651 (rank : 139)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	237	Target Neighborhood Hits	555	Shared Neighborhood Hits	45
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

RIN3_MOUSE
NC score	0.021588 (rank : 140)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	237	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

CSKI1_MOUSE
NC score	0.021512 (rank : 141)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	237	Target Neighborhood Hits	1031	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TULP1_HUMAN
NC score	0.021441 (rank : 142)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	237	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

IF35_MOUSE
NC score	0.021350 (rank : 143)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	237	Target Neighborhood Hits	210	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

MYT1L_HUMAN
NC score	0.021159 (rank : 144)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	237	Target Neighborhood Hits	471	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

GP158_HUMAN
NC score	0.021120 (rank : 145)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	237	Target Neighborhood Hits	221	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

MILK2_HUMAN
NC score	0.021046 (rank : 146)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	237	Target Neighborhood Hits	457	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

FXL19_MOUSE
NC score	0.020675 (rank : 147)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	237	Target Neighborhood Hits	217	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

JADE2_MOUSE
NC score	0.020646 (rank : 148)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	237	Target Neighborhood Hits	560	Shared Neighborhood Hits	64
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

FOXR1_HUMAN
NC score	0.020473 (rank : 149)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	237	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PIV2, Q86UT9, Q8IXX2	Gene names	FOXR1, DLNB13, FOXN5
Domain Architecture	No domain graphic available
Description	Forkhead box protein R1 (Forkhead box protein N5).

WASF3_HUMAN
NC score	0.020046 (rank : 150)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	237	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

HCN4_MOUSE
NC score	0.019492 (rank : 151)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	237	Target Neighborhood Hits	284	Shared Neighborhood Hits	36
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

TTP_HUMAN
NC score	0.018657 (rank : 152)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	237	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

FREA_MOUSE
NC score	0.018500 (rank : 153)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	237	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

TDRD4_HUMAN
NC score	0.018376 (rank : 154)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	237	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUY9	Gene names	TDRD4
Domain Architecture
Description	Tudor domain-containing protein 4.

TBCD3_HUMAN
NC score	0.017512 (rank : 155)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	237	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

NFM_HUMAN
NC score	0.017476 (rank : 156)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	237	Target Neighborhood Hits	1328	Shared Neighborhood Hits	75
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

USH1C_MOUSE
NC score	0.017457 (rank : 157)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	237	Target Neighborhood Hits	557	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

RIF1_HUMAN
NC score	0.017283 (rank : 158)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	237	Target Neighborhood Hits	320	Shared Neighborhood Hits	17
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

COFA1_MOUSE
NC score	0.016963 (rank : 159)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	237	Target Neighborhood Hits	305	Shared Neighborhood Hits	24
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

MYO15_MOUSE
NC score	0.016885 (rank : 160)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	237	Target Neighborhood Hits	467	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PRP8_MOUSE
NC score	0.016670 (rank : 161)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	237	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PV0, Q5ND30, Q5ND31, Q7TQK2, Q8BRZ5, Q8K001	Gene names	Prpf8, Prp8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8).

PRP8_HUMAN
NC score	0.016667 (rank : 162)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	237	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P2Q9, O14547, O75965	Gene names	PRPF8, PRPC8
Domain Architecture	No domain graphic available
Description	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8) (PRP8 homolog) (220 kDa U5 snRNP-specific protein) (p220).

SYEP_HUMAN
NC score	0.016356 (rank : 163)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	237	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

CCD45_MOUSE
NC score	0.016216 (rank : 164)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	237	Target Neighborhood Hits	663	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

P3C2A_HUMAN
NC score	0.016040 (rank : 165)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	237	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

NPAS1_MOUSE
NC score	0.015903 (rank : 166)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	237	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

CN037_MOUSE
NC score	0.015783 (rank : 167)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	237	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

FGFP3_HUMAN
NC score	0.015658 (rank : 168)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	237	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

SI1L1_HUMAN
NC score	0.015550 (rank : 169)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	237	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

EVI2B_MOUSE
NC score	0.015428 (rank : 170)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	237	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

CAF1A_HUMAN
NC score	0.015344 (rank : 171)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	237	Target Neighborhood Hits	750	Shared Neighborhood Hits	31
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

PO2F2_MOUSE
NC score	0.014833 (rank : 172)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	237	Target Neighborhood Hits	353	Shared Neighborhood Hits	12
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

M3K9_HUMAN
NC score	0.014482 (rank : 173)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	237	Target Neighborhood Hits	1123	Shared Neighborhood Hits	52
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NCA11_MOUSE
NC score	0.013962 (rank : 174)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	237	Target Neighborhood Hits	661	Shared Neighborhood Hits	49
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NAF1_MOUSE
NC score	0.013474 (rank : 175)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	237	Target Neighborhood Hits	852	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PTPRN_HUMAN
NC score	0.013448 (rank : 176)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	237	Target Neighborhood Hits	156	Shared Neighborhood Hits	19
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

ANM8_HUMAN
NC score	0.013365 (rank : 177)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	237	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR22, Q8TBJ8	Gene names	PRMT8, HRMT1L3, HRMT1L4
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4).

TTP_MOUSE
NC score	0.013327 (rank : 178)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	237	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

IC1_MOUSE
NC score	0.013300 (rank : 179)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	237	Target Neighborhood Hits	164	Shared Neighborhood Hits	20
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

BPA1_MOUSE
NC score	0.012579 (rank : 180)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	237	Target Neighborhood Hits	1477	Shared Neighborhood Hits	49
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

IF4G3_HUMAN
NC score	0.012112 (rank : 181)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	237	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K1219_HUMAN
NC score	0.011851 (rank : 182)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	237	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

MYO15_HUMAN
NC score	0.011761 (rank : 183)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	237	Target Neighborhood Hits	671	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MAMC2_HUMAN
NC score	0.011738 (rank : 184)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	237	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

LYN_MOUSE
NC score	0.011532 (rank : 185)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	237	Target Neighborhood Hits	1023	Shared Neighborhood Hits	36
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

CO8A_MOUSE
NC score	0.011238 (rank : 186)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	237	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CAF1B_MOUSE
NC score	0.010857 (rank : 187)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	237	Target Neighborhood Hits	385	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CT2NL_MOUSE
NC score	0.010850 (rank : 188)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	237	Target Neighborhood Hits	902	Shared Neighborhood Hits	42
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

LYN_HUMAN
NC score	0.010683 (rank : 189)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	237	Target Neighborhood Hits	1022	Shared Neighborhood Hits	35
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

HDAC9_HUMAN
NC score	0.010279 (rank : 190)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	237	Target Neighborhood Hits	201	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

OTU7B_HUMAN
NC score	0.010222 (rank : 191)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	237	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

MAST4_HUMAN
NC score	0.010071 (rank : 192)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	237	Target Neighborhood Hits	1804	Shared Neighborhood Hits	98
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

LPHN1_HUMAN
NC score	0.010002 (rank : 193)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	237	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

GP1BA_HUMAN
NC score	0.009758 (rank : 194)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	237	Target Neighborhood Hits	407	Shared Neighborhood Hits	26
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

ANM8_MOUSE
NC score	0.009636 (rank : 195)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	237	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PAK3, Q7M6Z2	Gene names	Prmt8, Hrmt1l4
Domain Architecture	No domain graphic available
Description	Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4).

DPOLQ_HUMAN
NC score	0.009572 (rank : 196)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	237	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	O75417, O95160	Gene names	POLQ, POLH
Domain Architecture
Description	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta).

CAC1D_HUMAN
NC score	0.009492 (rank : 197)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	237	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

PLCB1_HUMAN
NC score	0.009471 (rank : 198)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	237	Target Neighborhood Hits	614	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

EPAS1_HUMAN
NC score	0.009445 (rank : 199)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	237	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

TITIN_HUMAN
NC score	0.009156 (rank : 200)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	237	Target Neighborhood Hits	2923	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SMP1L_HUMAN
NC score	0.009108 (rank : 201)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	237	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

M3K10_HUMAN
NC score	0.008831 (rank : 202)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	237	Target Neighborhood Hits	1071	Shared Neighborhood Hits	41
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

PLCB1_MOUSE
NC score	0.008727 (rank : 203)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	237	Target Neighborhood Hits	531	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

TMCC1_HUMAN
NC score	0.008151 (rank : 204)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	237	Target Neighborhood Hits	337	Shared Neighborhood Hits	11
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

WDHD1_HUMAN
NC score	0.007819 (rank : 205)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	237	Target Neighborhood Hits	342	Shared Neighborhood Hits	11
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

CUL4B_HUMAN
NC score	0.007766 (rank : 206)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	237	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

SPEG_HUMAN
NC score	0.007764 (rank : 207)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	237	Target Neighborhood Hits	1762	Shared Neighborhood Hits	82
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PLXB3_HUMAN
NC score	0.007657 (rank : 208)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	237	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

TECT3_MOUSE
NC score	0.007626 (rank : 209)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	237	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R2Q6, Q8CDF3, Q9CRC5	Gene names	Tect3
Domain Architecture	No domain graphic available
Description	Tectonic-3 precursor.

TSH2_MOUSE
NC score	0.007574 (rank : 210)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	237	Target Neighborhood Hits	467	Shared Neighborhood Hits	11
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

BPAEA_HUMAN
NC score	0.007394 (rank : 211)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	237	Target Neighborhood Hits	1369	Shared Neighborhood Hits	42
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GOGA4_HUMAN
NC score	0.007323 (rank : 212)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	237	Target Neighborhood Hits	2034	Shared Neighborhood Hits	56
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

SN1L1_HUMAN
NC score	0.007305 (rank : 213)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	237	Target Neighborhood Hits	911	Shared Neighborhood Hits	25
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

CUTL2_MOUSE
NC score	0.007102 (rank : 214)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	237	Target Neighborhood Hits	771	Shared Neighborhood Hits	42
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ZBTB4_HUMAN
NC score	0.007072 (rank : 215)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	237	Target Neighborhood Hits	926	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

ZN516_MOUSE
NC score	0.007038 (rank : 216)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	237	Target Neighborhood Hits	1197	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

AZI1_HUMAN
NC score	0.006848 (rank : 217)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	237	Target Neighborhood Hits	1000	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

OBSCN_HUMAN
NC score	0.006607 (rank : 218)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	237	Target Neighborhood Hits	1931	Shared Neighborhood Hits	89
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

CRBB3_MOUSE
NC score	0.005930 (rank : 219)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	237	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJU9	Gene names	Crybb3
Domain Architecture
Description	Beta crystallin B3 (Beta-B3-crystallin).

ELK1_HUMAN
NC score	0.005901 (rank : 220)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	237	Target Neighborhood Hits	112	Shared Neighborhood Hits	10
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

CAC1E_MOUSE
NC score	0.005808 (rank : 221)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	237	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

ACTN3_MOUSE
NC score	0.005774 (rank : 222)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	237	Target Neighborhood Hits	265	Shared Neighborhood Hits	12
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_HUMAN
NC score	0.005548 (rank : 223)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	237	Target Neighborhood Hits	272	Shared Neighborhood Hits	12
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

KCNC3_HUMAN
NC score	0.005296 (rank : 224)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	237	Target Neighborhood Hits	256	Shared Neighborhood Hits	30
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

PLSL_HUMAN
NC score	0.005171 (rank : 225)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	237	Target Neighborhood Hits	168	Shared Neighborhood Hits	8
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

KIRR2_MOUSE
NC score	0.004827 (rank : 226)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	237	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

NMDE3_HUMAN
NC score	0.004672 (rank : 227)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	237	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

SMRCD_HUMAN
NC score	0.003840 (rank : 228)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	237	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

LYAM2_MOUSE
NC score	0.003609 (rank : 229)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	237	Target Neighborhood Hits	420	Shared Neighborhood Hits	7
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LATS1_HUMAN
NC score	0.003005 (rank : 230)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	237	Target Neighborhood Hits	1057	Shared Neighborhood Hits	42
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

NKX24_HUMAN
NC score	0.002722 (rank : 231)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	237	Target Neighborhood Hits	366	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H2Z4	Gene names	NKX2-4, NKX2D
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

NOTC3_MOUSE
NC score	0.002221 (rank : 232)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	237	Target Neighborhood Hits	975	Shared Neighborhood Hits	36
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

M4K4_HUMAN
NC score	0.001940 (rank : 233)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	237	Target Neighborhood Hits	1589	Shared Neighborhood Hits	45
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

JAG2_MOUSE
NC score	0.001870 (rank : 234)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	237	Target Neighborhood Hits	504	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DAPK1_HUMAN
NC score	0.001120 (rank : 235)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	237	Target Neighborhood Hits	1130	Shared Neighborhood Hits	20
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_MOUSE
NC score	0.001048 (rank : 236)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	237	Target Neighborhood Hits	1138	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ROS_HUMAN
NC score	0.000785 (rank : 237)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	237	Target Neighborhood Hits	907	Shared Neighborhood Hits	16
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).