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Network neighborhood for query Sequence : NMDE3_HUMAN

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NMDE3_HUMAN
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NMDE1_HUMAN
θ value	0 (rank : 1)	NC score	0.986307 (rank : 8)
Query Neighborhood Hits	110	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

NMDE1_MOUSE
θ value	0 (rank : 2)	NC score	0.987121 (rank : 4)
Query Neighborhood Hits	110	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMDE2_HUMAN
θ value	0 (rank : 3)	NC score	0.987058 (rank : 5)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
θ value	0 (rank : 4)	NC score	0.986861 (rank : 7)
Query Neighborhood Hits	110	Target Neighborhood Hits	64	Shared Neighborhood Hits	34
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	110	Target Neighborhood Hits	110	Shared Neighborhood Hits	110
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE3_MOUSE
θ value	0 (rank : 6)	NC score	0.995986 (rank : 2)
Query Neighborhood Hits	110	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE4_HUMAN
θ value	0 (rank : 7)	NC score	0.988702 (rank : 3)
Query Neighborhood Hits	110	Target Neighborhood Hits	133	Shared Neighborhood Hits	43
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE4_MOUSE
θ value	0 (rank : 8)	NC score	0.986900 (rank : 6)
Query Neighborhood Hits	110	Target Neighborhood Hits	158	Shared Neighborhood Hits	47
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDZ1_MOUSE
θ value	2.73936e-73 (rank : 9)	NC score	0.909670 (rank : 13)
Query Neighborhood Hits	110	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_HUMAN
θ value	4.67263e-73 (rank : 10)	NC score	0.910096 (rank : 12)
Query Neighborhood Hits	110	Target Neighborhood Hits	77	Shared Neighborhood Hits	36
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMD3A_HUMAN
θ value	2.17053e-70 (rank : 11)	NC score	0.934014 (rank : 9)
Query Neighborhood Hits	110	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMD3B_MOUSE
θ value	3.70236e-70 (rank : 12)	NC score	0.927315 (rank : 10)
Query Neighborhood Hits	110	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

NMD3B_HUMAN
θ value	1.83746e-69 (rank : 13)	NC score	0.926551 (rank : 11)
Query Neighborhood Hits	110	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

GRIA1_MOUSE
θ value	1.97686e-47 (rank : 14)	NC score	0.835807 (rank : 25)
Query Neighborhood Hits	110	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_HUMAN
θ value	6.35935e-46 (rank : 15)	NC score	0.834346 (rank : 26)
Query Neighborhood Hits	110	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA4_HUMAN
θ value	8.30557e-46 (rank : 16)	NC score	0.832390 (rank : 27)
Query Neighborhood Hits	110	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_MOUSE
θ value	2.41655e-45 (rank : 17)	NC score	0.830302 (rank : 28)
Query Neighborhood Hits	110	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIK1_HUMAN
θ value	1.73182e-43 (rank : 18)	NC score	0.839973 (rank : 18)
Query Neighborhood Hits	110	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK4_HUMAN
θ value	1.73182e-43 (rank : 19)	NC score	0.840111 (rank : 17)
Query Neighborhood Hits	110	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK4_MOUSE
θ value	2.95404e-43 (rank : 20)	NC score	0.839872 (rank : 19)
Query Neighborhood Hits	110	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRIA2_HUMAN
θ value	1.91475e-42 (rank : 21)	NC score	0.829960 (rank : 29)
Query Neighborhood Hits	110	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIK2_HUMAN
θ value	2.50074e-42 (rank : 22)	NC score	0.838591 (rank : 20)
Query Neighborhood Hits	110	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIA2_MOUSE
θ value	5.57106e-42 (rank : 23)	NC score	0.829285 (rank : 30)
Query Neighborhood Hits	110	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIK3_HUMAN
θ value	8.04462e-41 (rank : 24)	NC score	0.840423 (rank : 16)
Query Neighborhood Hits	110	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIA3_HUMAN
θ value	3.05695e-40 (rank : 25)	NC score	0.829129 (rank : 31)
Query Neighborhood Hits	110	Target Neighborhood Hits	40	Shared Neighborhood Hits	33
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIK5_HUMAN
θ value	3.05695e-40 (rank : 26)	NC score	0.838540 (rank : 21)
Query Neighborhood Hits	110	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK5_MOUSE
θ value	3.99248e-40 (rank : 27)	NC score	0.838072 (rank : 22)
Query Neighborhood Hits	110	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRIA3_MOUSE
θ value	1.16164e-39 (rank : 28)	NC score	0.829127 (rank : 32)
Query Neighborhood Hits	110	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRID2_MOUSE
θ value	3.16345e-37 (rank : 29)	NC score	0.841839 (rank : 14)
Query Neighborhood Hits	110	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID2_HUMAN
θ value	4.13158e-37 (rank : 30)	NC score	0.840670 (rank : 15)
Query Neighborhood Hits	110	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID1_MOUSE
θ value	1.12514e-34 (rank : 31)	NC score	0.837708 (rank : 23)
Query Neighborhood Hits	110	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_HUMAN
θ value	6.17384e-33 (rank : 32)	NC score	0.835862 (rank : 24)
Query Neighborhood Hits	110	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRIK1_MOUSE
θ value	8.91499e-32 (rank : 33)	NC score	0.821361 (rank : 33)
Query Neighborhood Hits	110	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

TS1R1_MOUSE
θ value	0.000461057 (rank : 34)	NC score	0.061636 (rank : 35)
Query Neighborhood Hits	110	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R1_HUMAN
θ value	0.0330416 (rank : 35)	NC score	0.042023 (rank : 38)
Query Neighborhood Hits	110	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

CJ012_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.021870 (rank : 44)
Query Neighborhood Hits	110	Target Neighborhood Hits	467	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

ERB1_HUMAN
θ value	0.21417 (rank : 37)	NC score	0.134967 (rank : 34)
Query Neighborhood Hits	110	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ASB10_HUMAN
θ value	0.279714 (rank : 38)	NC score	0.007404 (rank : 78)
Query Neighborhood Hits	110	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB10_MOUSE
θ value	0.279714 (rank : 39)	NC score	0.007325 (rank : 79)
Query Neighborhood Hits	110	Target Neighborhood Hits	301	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

CK024_HUMAN
θ value	0.279714 (rank : 40)	NC score	0.029887 (rank : 39)
Query Neighborhood Hits	110	Target Neighborhood Hits	408	Shared Neighborhood Hits	19
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

TM55B_MOUSE
θ value	0.365318 (rank : 41)	NC score	0.018923 (rank : 47)
Query Neighborhood Hits	110	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TWL2	Gene names	Tmem55b
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55B (EC 3.1.3.-) (Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase I).

OGFR_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.016053 (rank : 53)
Query Neighborhood Hits	110	Target Neighborhood Hits	1582	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PROP_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.008533 (rank : 74)
Query Neighborhood Hits	110	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PRRT3_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.024750 (rank : 41)
Query Neighborhood Hits	110	Target Neighborhood Hits	998	Shared Neighborhood Hits	29
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SRRM2_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.013910 (rank : 63)
Query Neighborhood Hits	110	Target Neighborhood Hits	1470	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ATP4A_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.017123 (rank : 48)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	P20648, O00738	Gene names	ATP4A
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Proton pump) (Gastric H+/K+ ATPase subunit alpha).

CHSP1_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.025293 (rank : 40)
Query Neighborhood Hits	110	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR86	Gene names	Carhsp1
Domain Architecture
Description	Calcium-regulated heat stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24).

DBND2_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.020239 (rank : 45)
Query Neighborhood Hits	110	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQY9, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31	Gene names	DBNDD2, C20orf35
Domain Architecture
Description	Dysbindin domain-containing protein 2 (HSMNP1).

FOXN1_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.014256 (rank : 62)
Query Neighborhood Hits	110	Target Neighborhood Hits	300	Shared Neighborhood Hits	12
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

ATP4A_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.016830 (rank : 51)
Query Neighborhood Hits	110	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q64436, Q9CV46	Gene names	Atp4a
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Proton pump) (Gastric H+/K+ ATPase subunit alpha).

RGS3_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.008267 (rank : 75)
Query Neighborhood Hits	110	Target Neighborhood Hits	1375	Shared Neighborhood Hits	25
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SRRM2_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.011521 (rank : 66)
Query Neighborhood Hits	110	Target Neighborhood Hits	1296	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TCGAP_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.023844 (rank : 42)
Query Neighborhood Hits	110	Target Neighborhood Hits	872	Shared Neighborhood Hits	22
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

AT1A4_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.016371 (rank : 52)
Query Neighborhood Hits	110	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WV27, Q9R173, Q9WV28	Gene names	Atp1a4, Atp1al2
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-4 chain (EC 3.6.3.9) (Sodium pump 4) (Na+/K+ ATPase 4).

ATS13_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.010804 (rank : 68)
Query Neighborhood Hits	110	Target Neighborhood Hits	238	Shared Neighborhood Hits	10
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

KRA47_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.007805 (rank : 77)
Query Neighborhood Hits	110	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

MAGD1_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.011384 (rank : 67)
Query Neighborhood Hits	110	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

SPT5H_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.017015 (rank : 50)
Query Neighborhood Hits	110	Target Neighborhood Hits	436	Shared Neighborhood Hits	17
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.017094 (rank : 49)
Query Neighborhood Hits	110	Target Neighborhood Hits	437	Shared Neighborhood Hits	17
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

NCOA6_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.020194 (rank : 46)
Query Neighborhood Hits	110	Target Neighborhood Hits	1202	Shared Neighborhood Hits	35
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.023156 (rank : 43)
Query Neighborhood Hits	110	Target Neighborhood Hits	1076	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

CASC3_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.012805 (rank : 64)
Query Neighborhood Hits	110	Target Neighborhood Hits	333	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

DOK3_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.008716 (rank : 72)
Query Neighborhood Hits	110	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

GA2L2_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.009758 (rank : 70)
Query Neighborhood Hits	110	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

NCOR2_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.006827 (rank : 80)
Query Neighborhood Hits	110	Target Neighborhood Hits	870	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PRGC2_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.009863 (rank : 69)
Query Neighborhood Hits	110	Target Neighborhood Hits	272	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

UBP44_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.006679 (rank : 81)
Query Neighborhood Hits	110	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

JIP3_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.003386 (rank : 100)
Query Neighborhood Hits	110	Target Neighborhood Hits	1039	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

K1199_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.007855 (rank : 76)
Query Neighborhood Hits	110	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BI06, Q6L9J4, Q9EPQ3, Q9EPQ4	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1199 homolog precursor (Protein 12H19.01.T7).

AT1A2_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.015478 (rank : 56)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	P50993, Q07059, Q86UZ5, Q9UQ25	Gene names	ATP1A2, KIAA0778
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-2 chain precursor (EC 3.6.3.9) (Sodium pump 2) (Na+/K+ ATPase 2).

AT1A2_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.015464 (rank : 57)
Query Neighborhood Hits	110	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PIE5	Gene names	Atp1a2
Domain Architecture	No domain graphic available
Description	Sodium/potassium-transporting ATPase alpha-2 chain precursor (EC 3.6.3.9) (Sodium pump 2) (Na+/K+ ATPase 2) (Alpha(+)).

AT1A3_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.015695 (rank : 55)
Query Neighborhood Hits	110	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	P13637, Q16732, Q16735, Q969K5	Gene names	ATP1A3
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-3 chain (EC 3.6.3.9) (Sodium pump 3) (Na+/K+ ATPase 3) (Alpha(III)).

AT1A3_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.015703 (rank : 54)
Query Neighborhood Hits	110	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PIC6	Gene names	Atp1a3
Domain Architecture	No domain graphic available
Description	Sodium/potassium-transporting ATPase alpha-3 chain (EC 3.6.3.9) (Sodium pump 3) (Na+/K+ ATPase 3) (Alpha(III)).

ATS1_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.005215 (rank : 86)
Query Neighborhood Hits	110	Target Neighborhood Hits	159	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.005131 (rank : 87)
Query Neighborhood Hits	110	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATX7_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.006426 (rank : 84)
Query Neighborhood Hits	110	Target Neighborhood Hits	351	Shared Neighborhood Hits	8
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CABIN_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.014437 (rank : 61)
Query Neighborhood Hits	110	Target Neighborhood Hits	490	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CT174_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.011898 (rank : 65)
Query Neighborhood Hits	110	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

MISS_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.006461 (rank : 83)
Query Neighborhood Hits	110	Target Neighborhood Hits	444	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

SLIT1_HUMAN
θ value	5.27518 (rank : 80)	NC score	-0.002760 (rank : 109)
Query Neighborhood Hits	110	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

WEE1_MOUSE
θ value	5.27518 (rank : 81)	NC score	-0.003077 (rank : 110)
Query Neighborhood Hits	110	Target Neighborhood Hits	794	Shared Neighborhood Hits	5
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

ZN516_MOUSE
θ value	5.27518 (rank : 82)	NC score	-0.001578 (rank : 107)
Query Neighborhood Hits	110	Target Neighborhood Hits	1197	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

AT12A_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.015241 (rank : 59)
Query Neighborhood Hits	110	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1W8, Q8VHY2	Gene names	Atp12a, Atp1al1
Domain Architecture	No domain graphic available
Description	Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Proton pump) (Non-gastric H(+)/K(+) ATPase subunit alpha).

AT1A4_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.015275 (rank : 58)
Query Neighborhood Hits	110	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q13733, Q504T2, Q8TBN8, Q8WXA7, Q8WXH7, Q8WY13	Gene names	ATP1A4, ATP1AL2
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-4 chain (EC 3.6.3.9) (Sodium pump 4) (Na+/K+ ATPase 4).

ATS2_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.004553 (rank : 97)
Query Neighborhood Hits	110	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS5_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.004772 (rank : 91)
Query Neighborhood Hits	110	Target Neighborhood Hits	147	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

AUXI_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.004661 (rank : 94)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

BCL9_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.005118 (rank : 88)
Query Neighborhood Hits	110	Target Neighborhood Hits	1008	Shared Neighborhood Hits	18
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CAN3_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.001624 (rank : 104)
Query Neighborhood Hits	110	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CCD45_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.001075 (rank : 106)
Query Neighborhood Hits	110	Target Neighborhood Hits	663	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

EFS_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.008659 (rank : 73)
Query Neighborhood Hits	110	Target Neighborhood Hits	348	Shared Neighborhood Hits	14
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

FOXO4_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.002547 (rank : 103)
Query Neighborhood Hits	110	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVH3	Gene names	Mllt7, Afx, Afx1, Fkhr3, Foxo4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Afxh) (Forkhead box protein O4).

KC1G1_MOUSE
θ value	6.88961 (rank : 93)	NC score	-0.002599 (rank : 108)
Query Neighborhood Hits	110	Target Neighborhood Hits	713	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTH8	Gene names	Csnk1g1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

KR414_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.004723 (rank : 92)
Query Neighborhood Hits	110	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA45_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.005074 (rank : 89)
Query Neighborhood Hits	110	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LBN_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.003344 (rank : 101)
Query Neighborhood Hits	110	Target Neighborhood Hits	308	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

M3K11_HUMAN
θ value	6.88961 (rank : 97)	NC score	-0.004669 (rank : 112)
Query Neighborhood Hits	110	Target Neighborhood Hits	1136	Shared Neighborhood Hits	16
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

RECQ5_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.003687 (rank : 99)
Query Neighborhood Hits	110	Target Neighborhood Hits	390	Shared Neighborhood Hits	12
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SON_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.009554 (rank : 71)
Query Neighborhood Hits	110	Target Neighborhood Hits	1568	Shared Neighborhood Hits	31
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SYP2L_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.005702 (rank : 85)
Query Neighborhood Hits	110	Target Neighborhood Hits	400	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

XKR7_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.004260 (rank : 98)
Query Neighborhood Hits	110	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q5GH72, Q9NUG5	Gene names	XKR7, C20orf159, XRG7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

ZBTB3_HUMAN
θ value	6.88961 (rank : 102)	NC score	-0.003281 (rank : 111)
Query Neighborhood Hits	110	Target Neighborhood Hits	910	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

AT12A_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.014941 (rank : 60)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	P54707, Q13816, Q13817, Q16734	Gene names	ATP12A, ATP1AL1
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Proton pump) (Non-gastric H(+)/K(+) ATPase subunit alpha).

BCL9_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.006666 (rank : 82)
Query Neighborhood Hits	110	Target Neighborhood Hits	770	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CIAS1_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.002775 (rank : 102)
Query Neighborhood Hits	110	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

CTDP1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.004575 (rank : 96)
Query Neighborhood Hits	110	Target Neighborhood Hits	416	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

CTGE4_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.001408 (rank : 105)
Query Neighborhood Hits	110	Target Neighborhood Hits	393	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

DOCK4_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.004672 (rank : 93)
Query Neighborhood Hits	110	Target Neighborhood Hits	237	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.004630 (rank : 95)
Query Neighborhood Hits	110	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

K0460_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.005032 (rank : 90)
Query Neighborhood Hits	110	Target Neighborhood Hits	374	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

GABR1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.052940 (rank : 36)
Query Neighborhood Hits	110	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.052808 (rank : 37)
Query Neighborhood Hits	110	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

Hits sorted by NC score

NMDE3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	110	Target Neighborhood Hits	110	Shared Neighborhood Hits	110
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE3_MOUSE
NC score	0.995986 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	110	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE4_HUMAN
NC score	0.988702 (rank : 3)	θ value	0 (rank : 7)
Query Neighborhood Hits	110	Target Neighborhood Hits	133	Shared Neighborhood Hits	43
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE1_MOUSE
NC score	0.987121 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	110	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMDE2_HUMAN
NC score	0.987058 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE4_MOUSE
NC score	0.986900 (rank : 6)	θ value	0 (rank : 8)
Query Neighborhood Hits	110	Target Neighborhood Hits	158	Shared Neighborhood Hits	47
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDE2_MOUSE
NC score	0.986861 (rank : 7)	θ value	0 (rank : 4)
Query Neighborhood Hits	110	Target Neighborhood Hits	64	Shared Neighborhood Hits	34
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE1_HUMAN
NC score	0.986307 (rank : 8)	θ value	0 (rank : 1)
Query Neighborhood Hits	110	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

NMD3A_HUMAN
NC score	0.934014 (rank : 9)	θ value	2.17053e-70 (rank : 11)
Query Neighborhood Hits	110	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMD3B_MOUSE
NC score	0.927315 (rank : 10)	θ value	3.70236e-70 (rank : 12)
Query Neighborhood Hits	110	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

NMD3B_HUMAN
NC score	0.926551 (rank : 11)	θ value	1.83746e-69 (rank : 13)
Query Neighborhood Hits	110	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

NMDZ1_HUMAN
NC score	0.910096 (rank : 12)	θ value	4.67263e-73 (rank : 10)
Query Neighborhood Hits	110	Target Neighborhood Hits	77	Shared Neighborhood Hits	36
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_MOUSE
NC score	0.909670 (rank : 13)	θ value	2.73936e-73 (rank : 9)
Query Neighborhood Hits	110	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GRID2_MOUSE
NC score	0.841839 (rank : 14)	θ value	3.16345e-37 (rank : 29)
Query Neighborhood Hits	110	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID2_HUMAN
NC score	0.840670 (rank : 15)	θ value	4.13158e-37 (rank : 30)
Query Neighborhood Hits	110	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRIK3_HUMAN
NC score	0.840423 (rank : 16)	θ value	8.04462e-41 (rank : 24)
Query Neighborhood Hits	110	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK4_HUMAN
NC score	0.840111 (rank : 17)	θ value	1.73182e-43 (rank : 19)
Query Neighborhood Hits	110	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK1_HUMAN
NC score	0.839973 (rank : 18)	θ value	1.73182e-43 (rank : 18)
Query Neighborhood Hits	110	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK4_MOUSE
NC score	0.839872 (rank : 19)	θ value	2.95404e-43 (rank : 20)
Query Neighborhood Hits	110	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRIK2_HUMAN
NC score	0.838591 (rank : 20)	θ value	2.50074e-42 (rank : 22)
Query Neighborhood Hits	110	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK5_HUMAN
NC score	0.838540 (rank : 21)	θ value	3.05695e-40 (rank : 26)
Query Neighborhood Hits	110	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK5_MOUSE
NC score	0.838072 (rank : 22)	θ value	3.99248e-40 (rank : 27)
Query Neighborhood Hits	110	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRID1_MOUSE
NC score	0.837708 (rank : 23)	θ value	1.12514e-34 (rank : 31)
Query Neighborhood Hits	110	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_HUMAN
NC score	0.835862 (rank : 24)	θ value	6.17384e-33 (rank : 32)
Query Neighborhood Hits	110	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRIA1_MOUSE
NC score	0.835807 (rank : 25)	θ value	1.97686e-47 (rank : 14)
Query Neighborhood Hits	110	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_HUMAN
NC score	0.834346 (rank : 26)	θ value	6.35935e-46 (rank : 15)
Query Neighborhood Hits	110	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA4_HUMAN
NC score	0.832390 (rank : 27)	θ value	8.30557e-46 (rank : 16)
Query Neighborhood Hits	110	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_MOUSE
NC score	0.830302 (rank : 28)	θ value	2.41655e-45 (rank : 17)
Query Neighborhood Hits	110	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA2_HUMAN
NC score	0.829960 (rank : 29)	θ value	1.91475e-42 (rank : 21)
Query Neighborhood Hits	110	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_MOUSE
NC score	0.829285 (rank : 30)	θ value	5.57106e-42 (rank : 23)
Query Neighborhood Hits	110	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA3_HUMAN
NC score	0.829129 (rank : 31)	θ value	3.05695e-40 (rank : 25)
Query Neighborhood Hits	110	Target Neighborhood Hits	40	Shared Neighborhood Hits	33
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA3_MOUSE
NC score	0.829127 (rank : 32)	θ value	1.16164e-39 (rank : 28)
Query Neighborhood Hits	110	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIK1_MOUSE
NC score	0.821361 (rank : 33)	θ value	8.91499e-32 (rank : 33)
Query Neighborhood Hits	110	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

ERB1_HUMAN
NC score	0.134967 (rank : 34)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	110	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

TS1R1_MOUSE
NC score	0.061636 (rank : 35)	θ value	0.000461057 (rank : 34)
Query Neighborhood Hits	110	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

GABR1_HUMAN
NC score	0.052940 (rank : 36)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	110	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.052808 (rank : 37)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	110	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

TS1R1_HUMAN
NC score	0.042023 (rank : 38)	θ value	0.0330416 (rank : 35)
Query Neighborhood Hits	110	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

CK024_HUMAN
NC score	0.029887 (rank : 39)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	110	Target Neighborhood Hits	408	Shared Neighborhood Hits	19
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CHSP1_MOUSE
NC score	0.025293 (rank : 40)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	110	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR86	Gene names	Carhsp1
Domain Architecture
Description	Calcium-regulated heat stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24).

PRRT3_HUMAN
NC score	0.024750 (rank : 41)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	110	Target Neighborhood Hits	998	Shared Neighborhood Hits	29
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TCGAP_HUMAN
NC score	0.023844 (rank : 42)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	110	Target Neighborhood Hits	872	Shared Neighborhood Hits	22
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

NCOA6_MOUSE
NC score	0.023156 (rank : 43)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	110	Target Neighborhood Hits	1076	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

CJ012_HUMAN
NC score	0.021870 (rank : 44)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	110	Target Neighborhood Hits	467	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

DBND2_HUMAN
NC score	0.020239 (rank : 45)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	110	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQY9, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31	Gene names	DBNDD2, C20orf35
Domain Architecture
Description	Dysbindin domain-containing protein 2 (HSMNP1).

NCOA6_HUMAN
NC score	0.020194 (rank : 46)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	110	Target Neighborhood Hits	1202	Shared Neighborhood Hits	35
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TM55B_MOUSE
NC score	0.018923 (rank : 47)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	110	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TWL2	Gene names	Tmem55b
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55B (EC 3.1.3.-) (Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase I).

ATP4A_HUMAN
NC score	0.017123 (rank : 48)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	P20648, O00738	Gene names	ATP4A
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Proton pump) (Gastric H+/K+ ATPase subunit alpha).

SPT5H_MOUSE
NC score	0.017094 (rank : 49)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	110	Target Neighborhood Hits	437	Shared Neighborhood Hits	17
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.017015 (rank : 50)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	110	Target Neighborhood Hits	436	Shared Neighborhood Hits	17
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

ATP4A_MOUSE
NC score	0.016830 (rank : 51)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	110	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q64436, Q9CV46	Gene names	Atp4a
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Proton pump) (Gastric H+/K+ ATPase subunit alpha).

AT1A4_MOUSE
NC score	0.016371 (rank : 52)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	110	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WV27, Q9R173, Q9WV28	Gene names	Atp1a4, Atp1al2
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-4 chain (EC 3.6.3.9) (Sodium pump 4) (Na+/K+ ATPase 4).

OGFR_HUMAN
NC score	0.016053 (rank : 53)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	110	Target Neighborhood Hits	1582	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

AT1A3_MOUSE
NC score	0.015703 (rank : 54)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	110	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PIC6	Gene names	Atp1a3
Domain Architecture	No domain graphic available
Description	Sodium/potassium-transporting ATPase alpha-3 chain (EC 3.6.3.9) (Sodium pump 3) (Na+/K+ ATPase 3) (Alpha(III)).

AT1A3_HUMAN
NC score	0.015695 (rank : 55)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	110	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	P13637, Q16732, Q16735, Q969K5	Gene names	ATP1A3
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-3 chain (EC 3.6.3.9) (Sodium pump 3) (Na+/K+ ATPase 3) (Alpha(III)).

AT1A2_HUMAN
NC score	0.015478 (rank : 56)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	P50993, Q07059, Q86UZ5, Q9UQ25	Gene names	ATP1A2, KIAA0778
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-2 chain precursor (EC 3.6.3.9) (Sodium pump 2) (Na+/K+ ATPase 2).

AT1A2_MOUSE
NC score	0.015464 (rank : 57)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	110	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PIE5	Gene names	Atp1a2
Domain Architecture	No domain graphic available
Description	Sodium/potassium-transporting ATPase alpha-2 chain precursor (EC 3.6.3.9) (Sodium pump 2) (Na+/K+ ATPase 2) (Alpha(+)).

AT1A4_HUMAN
NC score	0.015275 (rank : 58)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	110	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q13733, Q504T2, Q8TBN8, Q8WXA7, Q8WXH7, Q8WY13	Gene names	ATP1A4, ATP1AL2
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-4 chain (EC 3.6.3.9) (Sodium pump 4) (Na+/K+ ATPase 4).

AT12A_MOUSE
NC score	0.015241 (rank : 59)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	110	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1W8, Q8VHY2	Gene names	Atp12a, Atp1al1
Domain Architecture	No domain graphic available
Description	Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Proton pump) (Non-gastric H(+)/K(+) ATPase subunit alpha).

AT12A_HUMAN
NC score	0.014941 (rank : 60)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	110	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	P54707, Q13816, Q13817, Q16734	Gene names	ATP12A, ATP1AL1
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Proton pump) (Non-gastric H(+)/K(+) ATPase subunit alpha).

CABIN_HUMAN
NC score	0.014437 (rank : 61)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	110	Target Neighborhood Hits	490	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

FOXN1_MOUSE
NC score	0.014256 (rank : 62)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	110	Target Neighborhood Hits	300	Shared Neighborhood Hits	12
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

SRRM2_MOUSE
NC score	0.013910 (rank : 63)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	110	Target Neighborhood Hits	1470	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CASC3_MOUSE
NC score	0.012805 (rank : 64)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	110	Target Neighborhood Hits	333	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CT174_HUMAN
NC score	0.011898 (rank : 65)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	110	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

SRRM2_HUMAN
NC score	0.011521 (rank : 66)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	110	Target Neighborhood Hits	1296	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MAGD1_HUMAN
NC score	0.011384 (rank : 67)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	110	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

ATS13_HUMAN
NC score	0.010804 (rank : 68)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	110	Target Neighborhood Hits	238	Shared Neighborhood Hits	10
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

PRGC2_HUMAN
NC score	0.009863 (rank : 69)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	110	Target Neighborhood Hits	272	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

GA2L2_MOUSE
NC score	0.009758 (rank : 70)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	110	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

SON_HUMAN
NC score	0.009554 (rank : 71)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	110	Target Neighborhood Hits	1568	Shared Neighborhood Hits	31
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DOK3_HUMAN
NC score	0.008716 (rank : 72)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	110	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

EFS_HUMAN
NC score	0.008659 (rank : 73)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	110	Target Neighborhood Hits	348	Shared Neighborhood Hits	14
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

PROP_MOUSE
NC score	0.008533 (rank : 74)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	110	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

RGS3_HUMAN
NC score	0.008267 (rank : 75)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	110	Target Neighborhood Hits	1375	Shared Neighborhood Hits	25
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

K1199_MOUSE
NC score	0.007855 (rank : 76)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	110	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BI06, Q6L9J4, Q9EPQ3, Q9EPQ4	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1199 homolog precursor (Protein 12H19.01.T7).

KRA47_HUMAN
NC score	0.007805 (rank : 77)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	110	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

ASB10_HUMAN
NC score	0.007404 (rank : 78)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	110	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB10_MOUSE
NC score	0.007325 (rank : 79)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	110	Target Neighborhood Hits	301	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

NCOR2_HUMAN
NC score	0.006827 (rank : 80)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	110	Target Neighborhood Hits	870	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

UBP44_HUMAN
NC score	0.006679 (rank : 81)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	110	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

BCL9_MOUSE
NC score	0.006666 (rank : 82)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	110	Target Neighborhood Hits	770	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MISS_MOUSE
NC score	0.006461 (rank : 83)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	110	Target Neighborhood Hits	444	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

ATX7_HUMAN
NC score	0.006426 (rank : 84)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	110	Target Neighborhood Hits	351	Shared Neighborhood Hits	8
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

SYP2L_HUMAN
NC score	0.005702 (rank : 85)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	110	Target Neighborhood Hits	400	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ATS1_HUMAN
NC score	0.005215 (rank : 86)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	110	Target Neighborhood Hits	159	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
NC score	0.005131 (rank : 87)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	110	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

BCL9_HUMAN
NC score	0.005118 (rank : 88)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	110	Target Neighborhood Hits	1008	Shared Neighborhood Hits	18
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

KRA45_HUMAN
NC score	0.005074 (rank : 89)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	110	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

K0460_MOUSE
NC score	0.005032 (rank : 90)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	110	Target Neighborhood Hits	374	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

ATS5_MOUSE
NC score	0.004772 (rank : 91)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	110	Target Neighborhood Hits	147	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

KR414_HUMAN
NC score	0.004723 (rank : 92)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	110	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

DOCK4_HUMAN
NC score	0.004672 (rank : 93)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	110	Target Neighborhood Hits	237	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

AUXI_MOUSE
NC score	0.004661 (rank : 94)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

DOCK4_MOUSE
NC score	0.004630 (rank : 95)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	110	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

CTDP1_HUMAN
NC score	0.004575 (rank : 96)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	110	Target Neighborhood Hits	416	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

ATS2_HUMAN
NC score	0.004553 (rank : 97)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	110	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

XKR7_HUMAN
NC score	0.004260 (rank : 98)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	110	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q5GH72, Q9NUG5	Gene names	XKR7, C20orf159, XRG7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

RECQ5_HUMAN
NC score	0.003687 (rank : 99)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	110	Target Neighborhood Hits	390	Shared Neighborhood Hits	12
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

JIP3_HUMAN
NC score	0.003386 (rank : 100)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	110	Target Neighborhood Hits	1039	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

LBN_HUMAN
NC score	0.003344 (rank : 101)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	110	Target Neighborhood Hits	308	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

CIAS1_MOUSE
NC score	0.002775 (rank : 102)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	110	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

FOXO4_MOUSE
NC score	0.002547 (rank : 103)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	110	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVH3	Gene names	Mllt7, Afx, Afx1, Fkhr3, Foxo4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Afxh) (Forkhead box protein O4).

CAN3_MOUSE
NC score	0.001624 (rank : 104)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	110	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CTGE4_HUMAN
NC score	0.001408 (rank : 105)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	110	Target Neighborhood Hits	393	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

CCD45_MOUSE
NC score	0.001075 (rank : 106)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	110	Target Neighborhood Hits	663	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

ZN516_MOUSE
NC score	-0.001578 (rank : 107)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	110	Target Neighborhood Hits	1197	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

KC1G1_MOUSE
NC score	-0.002599 (rank : 108)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	110	Target Neighborhood Hits	713	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTH8	Gene names	Csnk1g1
Domain Architecture
Description	Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma 1).

SLIT1_HUMAN
NC score	-0.002760 (rank : 109)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	110	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

WEE1_MOUSE
NC score	-0.003077 (rank : 110)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	110	Target Neighborhood Hits	794	Shared Neighborhood Hits	5
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

ZBTB3_HUMAN
NC score	-0.003281 (rank : 111)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	110	Target Neighborhood Hits	910	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

M3K11_HUMAN
NC score	-0.004669 (rank : 112)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	110	Target Neighborhood Hits	1136	Shared Neighborhood Hits	16
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).