Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : DBND2_HUMAN

For an explanation of this page, click here

DBND2_HUMAN
SwissProt Accessions	Q9BQY9, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31	Gene names	DBNDD2, C20orf35
Domain Architecture
Description	Dysbindin domain-containing protein 2 (HSMNP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DBND2_HUMAN
θ value	2.9938e-112 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BQY9, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31	Gene names	DBNDD2, C20orf35
Domain Architecture
Description	Dysbindin domain-containing protein 2 (HSMNP1).

DBND2_MOUSE
θ value	2.67181e-44 (rank : 2)	NC score	0.961593 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CRD4	Gene names	Dbndd2, D2Bwg0891e
Domain Architecture
Description	Dysbindin domain-containing protein 2.

DTBP1_HUMAN
θ value	3.28887e-18 (rank : 3)	NC score	0.629977 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	185	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

DTBP1_MOUSE
θ value	8.10077e-17 (rank : 4)	NC score	0.618548 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

LEO1_HUMAN
θ value	0.0736092 (rank : 5)	NC score	0.041471 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	958	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SMN_HUMAN
θ value	0.125558 (rank : 6)	NC score	0.100580 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

DIAP1_HUMAN
θ value	0.163984 (rank : 7)	NC score	0.074203 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	784	Shared Neighborhood Hits	11
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

IDD_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.077041 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

NMDE3_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.020239 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

WIRE_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.061401 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	329	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.062512 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	310	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ZN598_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.043799 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	339	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

CAD22_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.016342 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ99, O43205	Gene names	CDH22, C20orf25
Domain Architecture
Description	Cadherin-22 precursor (Pituitary and brain cadherin) (PB-cadherin).

CAD22_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.016257 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTP5	Gene names	Cdh22
Domain Architecture
Description	Cadherin-22 precursor (Pituitary and brain cadherin) (PB-cadherin).

DIAP1_MOUSE
θ value	1.38821 (rank : 15)	NC score	0.065553 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	839	Shared Neighborhood Hits	11
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

GNRP_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.024509 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

M3K11_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.004966 (rank : 43)
Query Neighborhood Hits	38	Target Neighborhood Hits	1136	Shared Neighborhood Hits	6
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

DAAM1_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.063934 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	443	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

FMN2_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.060089 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	484	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

IF4B_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.039468 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

DAAM1_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.062466 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	483	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DIAP2_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.068647 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

MBD6_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.032834 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	349	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PCQAP_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.035598 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	506	Shared Neighborhood Hits	6
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

NETR_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.006138 (rank : 42)
Query Neighborhood Hits	38	Target Neighborhood Hits	218	Shared Neighborhood Hits	2
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

PTN23_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.012927 (rank : 40)
Query Neighborhood Hits	38	Target Neighborhood Hits	726	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SRRM1_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.020975 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	966	Shared Neighborhood Hits	14
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CCD1A_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.025563 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

FMN2_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.060317 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	349	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

LAP4_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.006318 (rank : 41)
Query Neighborhood Hits	38	Target Neighborhood Hits	590	Shared Neighborhood Hits	2
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PCQAP_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.030216 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	549	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

WASP_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.018565 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	223	Shared Neighborhood Hits	5
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

B4GN4_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.013313 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

K0256_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.017278 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

OAS3_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.015037 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

SMN_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.062718 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

SON_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.025128 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	1568	Shared Neighborhood Hits	24
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TNR8_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.016417 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

DAAM2_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.050951 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	350	Shared Neighborhood Hits	7
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DAAM2_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.051773 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	371	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DIAP2_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.059390 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	342	Shared Neighborhood Hits	8
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DIAP3_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.056150 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	209	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

DIAP3_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.056068 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

Hits sorted by NC score

DBND2_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.9938e-112 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BQY9, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31	Gene names	DBNDD2, C20orf35
Domain Architecture
Description	Dysbindin domain-containing protein 2 (HSMNP1).

DBND2_MOUSE
NC score	0.961593 (rank : 2)	θ value	2.67181e-44 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CRD4	Gene names	Dbndd2, D2Bwg0891e
Domain Architecture
Description	Dysbindin domain-containing protein 2.

DTBP1_HUMAN
NC score	0.629977 (rank : 3)	θ value	3.28887e-18 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	185	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EV8, Q96NV2, Q9H0U2, Q9H3J5	Gene names	DTNBP1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein).

DTBP1_MOUSE
NC score	0.618548 (rank : 4)	θ value	8.10077e-17 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

SMN_HUMAN
NC score	0.100580 (rank : 5)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

IDD_MOUSE
NC score	0.077041 (rank : 6)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

DIAP1_HUMAN
NC score	0.074203 (rank : 7)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	784	Shared Neighborhood Hits	11
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP2_MOUSE
NC score	0.068647 (rank : 8)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

DIAP1_MOUSE
NC score	0.065553 (rank : 9)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	839	Shared Neighborhood Hits	11
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DAAM1_MOUSE
NC score	0.063934 (rank : 10)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	443	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

SMN_MOUSE
NC score	0.062718 (rank : 11)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

WIRE_MOUSE
NC score	0.062512 (rank : 12)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	310	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

DAAM1_HUMAN
NC score	0.062466 (rank : 13)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	483	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

WIRE_HUMAN
NC score	0.061401 (rank : 14)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	329	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

FMN2_MOUSE
NC score	0.060317 (rank : 15)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	349	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FMN2_HUMAN
NC score	0.060089 (rank : 16)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	484	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

DIAP2_HUMAN
NC score	0.059390 (rank : 17)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	38	Target Neighborhood Hits	342	Shared Neighborhood Hits	8
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DIAP3_HUMAN
NC score	0.056150 (rank : 18)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	38	Target Neighborhood Hits	209	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

DIAP3_MOUSE
NC score	0.056068 (rank : 19)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	38	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

DAAM2_MOUSE
NC score	0.051773 (rank : 20)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	38	Target Neighborhood Hits	371	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DAAM2_HUMAN
NC score	0.050951 (rank : 21)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	350	Shared Neighborhood Hits	7
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ZN598_HUMAN
NC score	0.043799 (rank : 22)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	339	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

LEO1_HUMAN
NC score	0.041471 (rank : 23)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	958	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

IF4B_MOUSE
NC score	0.039468 (rank : 24)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

PCQAP_MOUSE
NC score	0.035598 (rank : 25)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	506	Shared Neighborhood Hits	6
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

MBD6_HUMAN
NC score	0.032834 (rank : 26)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	349	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PCQAP_HUMAN
NC score	0.030216 (rank : 27)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	549	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

CCD1A_HUMAN
NC score	0.025563 (rank : 28)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

SON_HUMAN
NC score	0.025128 (rank : 29)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	1568	Shared Neighborhood Hits	24
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

GNRP_MOUSE
NC score	0.024509 (rank : 30)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

SRRM1_MOUSE
NC score	0.020975 (rank : 31)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	966	Shared Neighborhood Hits	14
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

NMDE3_HUMAN
NC score	0.020239 (rank : 32)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

WASP_MOUSE
NC score	0.018565 (rank : 33)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	223	Shared Neighborhood Hits	5
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

K0256_MOUSE
NC score	0.017278 (rank : 34)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

TNR8_MOUSE
NC score	0.016417 (rank : 35)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	208	Shared Neighborhood Hits	3
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

CAD22_HUMAN
NC score	0.016342 (rank : 36)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ99, O43205	Gene names	CDH22, C20orf25
Domain Architecture
Description	Cadherin-22 precursor (Pituitary and brain cadherin) (PB-cadherin).

CAD22_MOUSE
NC score	0.016257 (rank : 37)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTP5	Gene names	Cdh22
Domain Architecture
Description	Cadherin-22 precursor (Pituitary and brain cadherin) (PB-cadherin).

OAS3_HUMAN
NC score	0.015037 (rank : 38)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

B4GN4_HUMAN
NC score	0.013313 (rank : 39)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

PTN23_MOUSE
NC score	0.012927 (rank : 40)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	726	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

LAP4_MOUSE
NC score	0.006318 (rank : 41)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	590	Shared Neighborhood Hits	2
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

NETR_HUMAN
NC score	0.006138 (rank : 42)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	218	Shared Neighborhood Hits	2
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

M3K11_HUMAN
NC score	0.004966 (rank : 43)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	1136	Shared Neighborhood Hits	6
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).