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Network neighborhood for query Sequence : NPAS1_MOUSE

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NPAS1_MOUSE
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NPAS1_HUMAN
θ value	0 (rank : 1)	NC score	0.994444 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	77	Shared Neighborhood Hits	36
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NPAS1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS3_MOUSE
θ value	2.00348e-116 (rank : 3)	NC score	0.968990 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
θ value	1.69605e-115 (rank : 4)	NC score	0.971139 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

SIM2_MOUSE
θ value	1.5519e-76 (rank : 5)	NC score	0.952717 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	33
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SIM2_HUMAN
θ value	5.8972e-76 (rank : 6)	NC score	0.954256 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	32
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM1_MOUSE
θ value	4.99229e-75 (rank : 7)	NC score	0.947077 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM1_HUMAN
θ value	6.52014e-75 (rank : 8)	NC score	0.947809 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

EPAS1_MOUSE
θ value	1.23823e-49 (rank : 9)	NC score	0.900850 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	94	Shared Neighborhood Hits	32
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

EPAS1_HUMAN
θ value	4.70527e-49 (rank : 10)	NC score	0.901675 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HIF1A_MOUSE
θ value	8.02596e-49 (rank : 11)	NC score	0.909256 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

HIF1A_HUMAN
θ value	1.04822e-48 (rank : 12)	NC score	0.906407 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	118	Shared Neighborhood Hits	32
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

BMAL1_HUMAN
θ value	1.6852e-22 (rank : 13)	NC score	0.747095 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	32
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	8.36355e-22 (rank : 14)	NC score	0.744462 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

AHR_HUMAN
θ value	1.058e-16 (rank : 15)	NC score	0.801844 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
θ value	1.80466e-16 (rank : 16)	NC score	0.798201 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

CLOCK_MOUSE
θ value	2.20605e-14 (rank : 17)	NC score	0.704600 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	148	Shared Neighborhood Hits	34
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
θ value	6.41864e-14 (rank : 18)	NC score	0.706412 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

ARNT2_HUMAN
θ value	2.43908e-13 (rank : 19)	NC score	0.687367 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	4.16044e-13 (rank : 20)	NC score	0.685983 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

NPAS4_HUMAN
θ value	1.2105e-12 (rank : 21)	NC score	0.662743 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	214	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	3.52202e-12 (rank : 22)	NC score	0.650031 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	245	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NCOA1_MOUSE
θ value	7.84624e-12 (rank : 23)	NC score	0.611396 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	196	Shared Neighborhood Hits	38
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
θ value	1.33837e-11 (rank : 24)	NC score	0.608617 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

ARNT_MOUSE
θ value	3.89403e-11 (rank : 25)	NC score	0.662502 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	213	Shared Neighborhood Hits	33
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NCOA2_MOUSE
θ value	8.67504e-11 (rank : 26)	NC score	0.544182 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	281	Shared Neighborhood Hits	33
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA2_HUMAN
θ value	2.52405e-10 (rank : 27)	NC score	0.544865 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	281	Shared Neighborhood Hits	32
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

ARNT_HUMAN
θ value	9.59137e-10 (rank : 28)	NC score	0.673038 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS2_MOUSE
θ value	3.64472e-09 (rank : 29)	NC score	0.673607 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NPAS2_HUMAN
θ value	1.38499e-08 (rank : 30)	NC score	0.664367 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	150	Shared Neighborhood Hits	33
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NCOA3_HUMAN
θ value	6.87365e-08 (rank : 31)	NC score	0.537310 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	171	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA3_MOUSE
θ value	6.43352e-06 (rank : 32)	NC score	0.501054 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	203	Shared Neighborhood Hits	32
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

TCF8_MOUSE
θ value	0.0736092 (rank : 33)	NC score	0.005199 (rank : 79)
Query Neighborhood Hits	63	Target Neighborhood Hits	1067	Shared Neighborhood Hits	10
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

SELPL_MOUSE
θ value	0.365318 (rank : 34)	NC score	0.029516 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	588	Shared Neighborhood Hits	12
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SF3A2_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.024472 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	263	Shared Neighborhood Hits	7
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

LYL1_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.023966 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

ZAR1_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.021619 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	254	Shared Neighborhood Hits	4
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

AKA12_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.016782 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	825	Shared Neighborhood Hits	10
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

MLL2_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.018578 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	1788	Shared Neighborhood Hits	23
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TAL1_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.025758 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

TAL1_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.023402 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

CGRE1_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.022097 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	354	Shared Neighborhood Hits	4
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

PEX1_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.007456 (rank : 75)
Query Neighborhood Hits	63	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

RBBP6_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.015554 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	1014	Shared Neighborhood Hits	11
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

DOCK4_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.015903 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.014538 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	210	Shared Neighborhood Hits	7
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DDX51_MOUSE
θ value	3.0926 (rank : 47)	NC score	0.004500 (rank : 80)
Query Neighborhood Hits	63	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

GCH1_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.016783 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

JIP1_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.009932 (rank : 72)
Query Neighborhood Hits	63	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

ABCBA_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.003069 (rank : 81)
Query Neighborhood Hits	63	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

EGR4_HUMAN
θ value	4.03905 (rank : 51)	NC score	-0.000017 (rank : 84)
Query Neighborhood Hits	63	Target Neighborhood Hits	939	Shared Neighborhood Hits	9
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

MYBB_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.009567 (rank : 73)
Query Neighborhood Hits	63	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

MEF2B_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.008788 (rank : 74)
Query Neighborhood Hits	63	Target Neighborhood Hits	218	Shared Neighborhood Hits	7
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MLL3_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.014430 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NSBP1_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.006400 (rank : 77)
Query Neighborhood Hits	63	Target Neighborhood Hits	681	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

KLF2_MOUSE
θ value	6.88961 (rank : 56)	NC score	-0.001470 (rank : 85)
Query Neighborhood Hits	63	Target Neighborhood Hits	738	Shared Neighborhood Hits	6
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

LYL1_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.018596 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

SF3A2_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.020882 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

LMO6_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.002203 (rank : 83)
Query Neighborhood Hits	63	Target Neighborhood Hits	337	Shared Neighborhood Hits	3
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

PSL1_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.005296 (rank : 78)
Query Neighborhood Hits	63	Target Neighborhood Hits	650	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RBM12_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.010746 (rank : 71)
Query Neighborhood Hits	63	Target Neighborhood Hits	313	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

STX18_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.007095 (rank : 76)
Query Neighborhood Hits	63	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

TCRG1_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.002678 (rank : 82)
Query Neighborhood Hits	63	Target Neighborhood Hits	929	Shared Neighborhood Hits	9
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

HES5_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.052823 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

HEY1_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.075789 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.079145 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.085313 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.083912 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MITF_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.058166 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.059224 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.055104 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.055194 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

PER1_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.163680 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	215	Shared Neighborhood Hits	24
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.161573 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	235	Shared Neighborhood Hits	24
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER2_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.168204 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	170	Shared Neighborhood Hits	22
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER2_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.152180 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	325	Shared Neighborhood Hits	21
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PER3_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.160392 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	479	Shared Neighborhood Hits	30
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER3_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.182062 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

TCFL5_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.060532 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFE3_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.056068 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.055376 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.055388 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.052457 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.052433 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.051055 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

Hits sorted by NC score

NPAS1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
NC score	0.994444 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	77	Shared Neighborhood Hits	36
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NPAS3_HUMAN
NC score	0.971139 (rank : 3)	θ value	1.69605e-115 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_MOUSE
NC score	0.968990 (rank : 4)	θ value	2.00348e-116 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

SIM2_HUMAN
NC score	0.954256 (rank : 5)	θ value	5.8972e-76 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	32
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
NC score	0.952717 (rank : 6)	θ value	1.5519e-76 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	33
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SIM1_HUMAN
NC score	0.947809 (rank : 7)	θ value	6.52014e-75 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
NC score	0.947077 (rank : 8)	θ value	4.99229e-75 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

HIF1A_MOUSE
NC score	0.909256 (rank : 9)	θ value	8.02596e-49 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

HIF1A_HUMAN
NC score	0.906407 (rank : 10)	θ value	1.04822e-48 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	118	Shared Neighborhood Hits	32
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

EPAS1_HUMAN
NC score	0.901675 (rank : 11)	θ value	4.70527e-49 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
NC score	0.900850 (rank : 12)	θ value	1.23823e-49 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	94	Shared Neighborhood Hits	32
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

AHR_HUMAN
NC score	0.801844 (rank : 13)	θ value	1.058e-16 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
NC score	0.798201 (rank : 14)	θ value	1.80466e-16 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

BMAL1_HUMAN
NC score	0.747095 (rank : 15)	θ value	1.6852e-22 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	32
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.744462 (rank : 16)	θ value	8.36355e-22 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

CLOCK_HUMAN
NC score	0.706412 (rank : 17)	θ value	6.41864e-14 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
NC score	0.704600 (rank : 18)	θ value	2.20605e-14 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	148	Shared Neighborhood Hits	34
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

ARNT2_HUMAN
NC score	0.687367 (rank : 19)	θ value	2.43908e-13 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
NC score	0.685983 (rank : 20)	θ value	4.16044e-13 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

NPAS2_MOUSE
NC score	0.673607 (rank : 21)	θ value	3.64472e-09 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

ARNT_HUMAN
NC score	0.673038 (rank : 22)	θ value	9.59137e-10 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS2_HUMAN
NC score	0.664367 (rank : 23)	θ value	1.38499e-08 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	150	Shared Neighborhood Hits	33
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS4_HUMAN
NC score	0.662743 (rank : 24)	θ value	1.2105e-12 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	214	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

ARNT_MOUSE
NC score	0.662502 (rank : 25)	θ value	3.89403e-11 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	213	Shared Neighborhood Hits	33
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS4_MOUSE
NC score	0.650031 (rank : 26)	θ value	3.52202e-12 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	245	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NCOA1_MOUSE
NC score	0.611396 (rank : 27)	θ value	7.84624e-12 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	196	Shared Neighborhood Hits	38
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.608617 (rank : 28)	θ value	1.33837e-11 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA2_HUMAN
NC score	0.544865 (rank : 29)	θ value	2.52405e-10 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	281	Shared Neighborhood Hits	32
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA2_MOUSE
NC score	0.544182 (rank : 30)	θ value	8.67504e-11 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	281	Shared Neighborhood Hits	33
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA3_HUMAN
NC score	0.537310 (rank : 31)	θ value	6.87365e-08 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	171	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA3_MOUSE
NC score	0.501054 (rank : 32)	θ value	6.43352e-06 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	203	Shared Neighborhood Hits	32
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PER3_MOUSE
NC score	0.182062 (rank : 33)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	63	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER2_HUMAN
NC score	0.168204 (rank : 34)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	63	Target Neighborhood Hits	170	Shared Neighborhood Hits	22
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER1_HUMAN
NC score	0.163680 (rank : 35)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	63	Target Neighborhood Hits	215	Shared Neighborhood Hits	24
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
NC score	0.161573 (rank : 36)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	63	Target Neighborhood Hits	235	Shared Neighborhood Hits	24
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER3_HUMAN
NC score	0.160392 (rank : 37)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	63	Target Neighborhood Hits	479	Shared Neighborhood Hits	30
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_MOUSE
NC score	0.152180 (rank : 38)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	63	Target Neighborhood Hits	325	Shared Neighborhood Hits	21
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

HEY2_HUMAN
NC score	0.085313 (rank : 39)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.083912 (rank : 40)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_MOUSE
NC score	0.079145 (rank : 41)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY1_HUMAN
NC score	0.075789 (rank : 42)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

TCFL5_HUMAN
NC score	0.060532 (rank : 43)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

MITF_MOUSE
NC score	0.059224 (rank : 44)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_HUMAN
NC score	0.058166 (rank : 45)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFE3_HUMAN
NC score	0.056068 (rank : 46)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	63	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_MOUSE
NC score	0.055388 (rank : 47)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	63	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.055376 (rank : 48)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	63	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

MLX_MOUSE
NC score	0.055194 (rank : 49)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.055104 (rank : 50)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

HES5_MOUSE
NC score	0.052823 (rank : 51)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

USF1_HUMAN
NC score	0.052457 (rank : 52)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	63	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
NC score	0.052433 (rank : 53)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.051055 (rank : 54)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	63	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

SELPL_MOUSE
NC score	0.029516 (rank : 55)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	588	Shared Neighborhood Hits	12
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

TAL1_HUMAN
NC score	0.025758 (rank : 56)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

SF3A2_HUMAN
NC score	0.024472 (rank : 57)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	263	Shared Neighborhood Hits	7
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

LYL1_HUMAN
NC score	0.023966 (rank : 58)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

TAL1_MOUSE
NC score	0.023402 (rank : 59)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

CGRE1_HUMAN
NC score	0.022097 (rank : 60)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	354	Shared Neighborhood Hits	4
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

ZAR1_MOUSE
NC score	0.021619 (rank : 61)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	254	Shared Neighborhood Hits	4
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

SF3A2_MOUSE
NC score	0.020882 (rank : 62)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

LYL1_MOUSE
NC score	0.018596 (rank : 63)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

MLL2_HUMAN
NC score	0.018578 (rank : 64)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	1788	Shared Neighborhood Hits	23
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

GCH1_HUMAN
NC score	0.016783 (rank : 65)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

AKA12_HUMAN
NC score	0.016782 (rank : 66)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	825	Shared Neighborhood Hits	10
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DOCK4_HUMAN
NC score	0.015903 (rank : 67)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

RBBP6_MOUSE
NC score	0.015554 (rank : 68)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	1014	Shared Neighborhood Hits	11
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

DOCK4_MOUSE
NC score	0.014538 (rank : 69)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	210	Shared Neighborhood Hits	7
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MLL3_HUMAN
NC score	0.014430 (rank : 70)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RBM12_MOUSE
NC score	0.010746 (rank : 71)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	313	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

JIP1_HUMAN
NC score	0.009932 (rank : 72)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

MYBB_HUMAN
NC score	0.009567 (rank : 73)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

MEF2B_MOUSE
NC score	0.008788 (rank : 74)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	218	Shared Neighborhood Hits	7
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

PEX1_HUMAN
NC score	0.007456 (rank : 75)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

STX18_HUMAN
NC score	0.007095 (rank : 76)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

NSBP1_MOUSE
NC score	0.006400 (rank : 77)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	681	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PSL1_HUMAN
NC score	0.005296 (rank : 78)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	650	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

TCF8_MOUSE
NC score	0.005199 (rank : 79)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	1067	Shared Neighborhood Hits	10
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

DDX51_MOUSE
NC score	0.004500 (rank : 80)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

ABCBA_HUMAN
NC score	0.003069 (rank : 81)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

TCRG1_HUMAN
NC score	0.002678 (rank : 82)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	929	Shared Neighborhood Hits	9
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

LMO6_HUMAN
NC score	0.002203 (rank : 83)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	337	Shared Neighborhood Hits	3
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

EGR4_HUMAN
NC score	-0.000017 (rank : 84)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	939	Shared Neighborhood Hits	9
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

KLF2_MOUSE
NC score	-0.001470 (rank : 85)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	738	Shared Neighborhood Hits	6
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).