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Network neighborhood for query Sequence : SIM2_MOUSE

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SIM2_MOUSE
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SIM1_HUMAN
θ value	0 (rank : 1)	NC score	0.987961 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	62	Shared Neighborhood Hits	40
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
θ value	0 (rank : 2)	NC score	0.987324 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_HUMAN
θ value	0 (rank : 3)	NC score	0.995700 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

NPAS3_MOUSE
θ value	2.0926e-81 (rank : 5)	NC score	0.943133 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
θ value	4.66183e-81 (rank : 6)	NC score	0.944354 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS1_MOUSE
θ value	1.5519e-76 (rank : 7)	NC score	0.952717 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
θ value	5.51964e-74 (rank : 8)	NC score	0.951467 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

HIF1A_MOUSE
θ value	7.20884e-74 (rank : 9)	NC score	0.935205 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

HIF1A_HUMAN
θ value	3.57772e-73 (rank : 10)	NC score	0.932070 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	118	Shared Neighborhood Hits	37
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

EPAS1_HUMAN
θ value	7.98882e-65 (rank : 11)	NC score	0.924058 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
θ value	2.32439e-64 (rank : 12)	NC score	0.923554 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

AHR_MOUSE
θ value	1.85889e-29 (rank : 13)	NC score	0.837946 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

BMAL1_MOUSE
θ value	2.68423e-28 (rank : 14)	NC score	0.791611 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

AHR_HUMAN
θ value	4.57862e-28 (rank : 15)	NC score	0.838702 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

BMAL1_HUMAN
θ value	2.27234e-27 (rank : 16)	NC score	0.793017 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	115	Shared Neighborhood Hits	40
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

NPAS4_HUMAN
θ value	8.93572e-24 (rank : 17)	NC score	0.703375 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	214	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

ARNT2_HUMAN
θ value	1.16704e-23 (rank : 18)	NC score	0.747697 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	1.16704e-23 (rank : 19)	NC score	0.746194 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

CLOCK_HUMAN
θ value	2.87452e-22 (rank : 20)	NC score	0.759126 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
θ value	4.9032e-22 (rank : 21)	NC score	0.756072 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	148	Shared Neighborhood Hits	40
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

ARNT_MOUSE
θ value	1.42661e-21 (rank : 22)	NC score	0.723508 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	213	Shared Neighborhood Hits	43
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_HUMAN
θ value	1.2077e-20 (rank : 23)	NC score	0.735500 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS4_MOUSE
θ value	1.33526e-19 (rank : 24)	NC score	0.686735 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	245	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NPAS2_MOUSE
θ value	1.92812e-18 (rank : 25)	NC score	0.734706 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NCOA1_MOUSE
θ value	5.60996e-18 (rank : 26)	NC score	0.636165 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	196	Shared Neighborhood Hits	38
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NPAS2_HUMAN
θ value	3.63628e-17 (rank : 27)	NC score	0.726641 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	150	Shared Neighborhood Hits	42
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NCOA1_HUMAN
θ value	8.10077e-17 (rank : 28)	NC score	0.632476 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA2_HUMAN
θ value	5.08577e-11 (rank : 29)	NC score	0.557589 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	281	Shared Neighborhood Hits	34
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA3_HUMAN
θ value	3.29651e-10 (rank : 30)	NC score	0.555783 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA2_MOUSE
θ value	4.30538e-10 (rank : 31)	NC score	0.555552 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	281	Shared Neighborhood Hits	35
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA3_MOUSE
θ value	1.17247e-07 (rank : 32)	NC score	0.519152 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PER2_MOUSE
θ value	0.0193708 (rank : 33)	NC score	0.210808 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

SCND1_HUMAN
θ value	0.0193708 (rank : 34)	NC score	0.019841 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	P57086	Gene names	SCAND1, SDP1
Domain Architecture
Description	SCAN domain-containing protein 1.

TBCD1_MOUSE
θ value	0.0330416 (rank : 35)	NC score	0.026576 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	241	Shared Neighborhood Hits	3
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

US6NL_HUMAN
θ value	0.0431538 (rank : 36)	NC score	0.035853 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

PER2_HUMAN
θ value	0.0736092 (rank : 37)	NC score	0.230988 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	170	Shared Neighborhood Hits	27
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

SON_HUMAN
θ value	0.21417 (rank : 38)	NC score	0.022908 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	1568	Shared Neighborhood Hits	22
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PER3_HUMAN
θ value	0.279714 (rank : 39)	NC score	0.215369 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	479	Shared Neighborhood Hits	35
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SC24C_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.018336 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	662	Shared Neighborhood Hits	13
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ARI1B_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.019895 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	567	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

PER3_MOUSE
θ value	0.62314 (rank : 42)	NC score	0.239970 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

EXOC3_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.029849 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

FOXO1_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.010705 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

OGFR_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.013208 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	1582	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BSN_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.028980 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	1537	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

HNF3B_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.006812 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P35583, Q60602	Gene names	Foxa2, Hnf3b, Tcf-3b, Tcf3b
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

HEY2_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.113296 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.111543 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

JHD2B_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.011758 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

NRX2A_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.008565 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	614	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.012492 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	481	Shared Neighborhood Hits	7
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SOX13_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.006911 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	495	Shared Neighborhood Hits	6
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

DC1L2_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.011497 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

HEY1_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.102612 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.106259 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

LTB1L_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.003521 (rank : 86)
Query Neighborhood Hits	75	Target Neighborhood Hits	553	Shared Neighborhood Hits	5
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.003539 (rank : 85)
Query Neighborhood Hits	75	Target Neighborhood Hits	502	Shared Neighborhood Hits	5
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DC12_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.014806 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96FZ2, Q96G34, Q9NRP3	Gene names	C3orf37
Domain Architecture	No domain graphic available
Description	UPF0361 protein DC12.

ZO1_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.006296 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	474	Shared Neighborhood Hits	4
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CX045_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.017696 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H5U8, Q5JXY9	Gene names	CXorf45
Domain Architecture	No domain graphic available
Description	Protein CXorf45.

ELF4_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.006212 (rank : 80)
Query Neighborhood Hits	75	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

NRIP1_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.010999 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P48552, Q8IWE8	Gene names	NRIP1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

GLIS1_HUMAN
θ value	5.27518 (rank : 64)	NC score	-0.003242 (rank : 89)
Query Neighborhood Hits	75	Target Neighborhood Hits	748	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

MAST3_HUMAN
θ value	5.27518 (rank : 65)	NC score	-0.003696 (rank : 90)
Query Neighborhood Hits	75	Target Neighborhood Hits	1128	Shared Neighborhood Hits	7
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MEF2B_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.007722 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

EXOC3_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.016811 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	O60645, Q8TEN6, Q8WUW0, Q96DI4	Gene names	EXOC3, SEC6, SEC6L1
Domain Architecture
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

HXB9_HUMAN
θ value	6.88961 (rank : 68)	NC score	-0.000317 (rank : 88)
Query Neighborhood Hits	75	Target Neighborhood Hits	344	Shared Neighborhood Hits	2
SwissProt Accessions	P17482, Q9H1I1	Gene names	HOXB9, HOX2E
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5).

NFAC3_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.005620 (rank : 82)
Query Neighborhood Hits	75	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

SEPT9_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.003701 (rank : 84)
Query Neighborhood Hits	75	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TAL1_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.010249 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

HNF3B_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.004527 (rank : 83)
Query Neighborhood Hits	75	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y261, Q8WUW4, Q96DF7	Gene names	FOXA2, HNF3B, TCF3B
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

K0528_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.005960 (rank : 81)
Query Neighborhood Hits	75	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

MLL4_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.007450 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	722	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TLE1_MOUSE
θ value	8.99809 (rank : 75)	NC score	0.000981 (rank : 87)
Query Neighborhood Hits	75	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

HES5_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.069140 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	38	Shared Neighborhood Hits	16
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

MITF_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.068644 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.070131 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	115	Shared Neighborhood Hits	20
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.064261 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.064308 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	100	Shared Neighborhood Hits	17
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

PER1_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.215064 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	215	Shared Neighborhood Hits	30
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.211428 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	235	Shared Neighborhood Hits	31
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

TCFL5_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.068799 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFE3_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.068024 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	190	Shared Neighborhood Hits	16
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.064606 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	111	Shared Neighborhood Hits	17
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.064469 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	119	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.063887 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.063858 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	71	Shared Neighborhood Hits	12
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.061674 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.057653 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

Hits sorted by NC score

SIM2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SIM2_HUMAN
NC score	0.995700 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM1_HUMAN
NC score	0.987961 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	62	Shared Neighborhood Hits	40
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
NC score	0.987324 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

NPAS1_MOUSE
NC score	0.952717 (rank : 5)	θ value	1.5519e-76 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
NC score	0.951467 (rank : 6)	θ value	5.51964e-74 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NPAS3_HUMAN
NC score	0.944354 (rank : 7)	θ value	4.66183e-81 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_MOUSE
NC score	0.943133 (rank : 8)	θ value	2.0926e-81 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

HIF1A_MOUSE
NC score	0.935205 (rank : 9)	θ value	7.20884e-74 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

HIF1A_HUMAN
NC score	0.932070 (rank : 10)	θ value	3.57772e-73 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	118	Shared Neighborhood Hits	37
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

EPAS1_HUMAN
NC score	0.924058 (rank : 11)	θ value	7.98882e-65 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
NC score	0.923554 (rank : 12)	θ value	2.32439e-64 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

AHR_HUMAN
NC score	0.838702 (rank : 13)	θ value	4.57862e-28 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
NC score	0.837946 (rank : 14)	θ value	1.85889e-29 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

BMAL1_HUMAN
NC score	0.793017 (rank : 15)	θ value	2.27234e-27 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	115	Shared Neighborhood Hits	40
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.791611 (rank : 16)	θ value	2.68423e-28 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

CLOCK_HUMAN
NC score	0.759126 (rank : 17)	θ value	2.87452e-22 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
NC score	0.756072 (rank : 18)	θ value	4.9032e-22 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	148	Shared Neighborhood Hits	40
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

ARNT2_HUMAN
NC score	0.747697 (rank : 19)	θ value	1.16704e-23 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
NC score	0.746194 (rank : 20)	θ value	1.16704e-23 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_HUMAN
NC score	0.735500 (rank : 21)	θ value	1.2077e-20 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS2_MOUSE
NC score	0.734706 (rank : 22)	θ value	1.92812e-18 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NPAS2_HUMAN
NC score	0.726641 (rank : 23)	θ value	3.63628e-17 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	150	Shared Neighborhood Hits	42
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

ARNT_MOUSE
NC score	0.723508 (rank : 24)	θ value	1.42661e-21 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	213	Shared Neighborhood Hits	43
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS4_HUMAN
NC score	0.703375 (rank : 25)	θ value	8.93572e-24 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	214	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
NC score	0.686735 (rank : 26)	θ value	1.33526e-19 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	245	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NCOA1_MOUSE
NC score	0.636165 (rank : 27)	θ value	5.60996e-18 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	196	Shared Neighborhood Hits	38
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.632476 (rank : 28)	θ value	8.10077e-17 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA2_HUMAN
NC score	0.557589 (rank : 29)	θ value	5.08577e-11 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	281	Shared Neighborhood Hits	34
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA3_HUMAN
NC score	0.555783 (rank : 30)	θ value	3.29651e-10 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA2_MOUSE
NC score	0.555552 (rank : 31)	θ value	4.30538e-10 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	281	Shared Neighborhood Hits	35
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA3_MOUSE
NC score	0.519152 (rank : 32)	θ value	1.17247e-07 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PER3_MOUSE
NC score	0.239970 (rank : 33)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER2_HUMAN
NC score	0.230988 (rank : 34)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	170	Shared Neighborhood Hits	27
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER3_HUMAN
NC score	0.215369 (rank : 35)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	479	Shared Neighborhood Hits	35
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER1_HUMAN
NC score	0.215064 (rank : 36)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	75	Target Neighborhood Hits	215	Shared Neighborhood Hits	30
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
NC score	0.211428 (rank : 37)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	75	Target Neighborhood Hits	235	Shared Neighborhood Hits	31
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER2_MOUSE
NC score	0.210808 (rank : 38)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

HEY2_HUMAN
NC score	0.113296 (rank : 39)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.111543 (rank : 40)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_MOUSE
NC score	0.106259 (rank : 41)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY1_HUMAN
NC score	0.102612 (rank : 42)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

MITF_MOUSE
NC score	0.070131 (rank : 43)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	115	Shared Neighborhood Hits	20
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

HES5_MOUSE
NC score	0.069140 (rank : 44)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	38	Shared Neighborhood Hits	16
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

TCFL5_HUMAN
NC score	0.068799 (rank : 45)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	75	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

MITF_HUMAN
NC score	0.068644 (rank : 46)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFE3_HUMAN
NC score	0.068024 (rank : 47)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	75	Target Neighborhood Hits	190	Shared Neighborhood Hits	16
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_HUMAN
NC score	0.064606 (rank : 48)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	75	Target Neighborhood Hits	111	Shared Neighborhood Hits	17
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
NC score	0.064469 (rank : 49)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	75	Target Neighborhood Hits	119	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

MLX_MOUSE
NC score	0.064308 (rank : 50)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	75	Target Neighborhood Hits	100	Shared Neighborhood Hits	17
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.064261 (rank : 51)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

USF1_HUMAN
NC score	0.063887 (rank : 52)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	75	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
NC score	0.063858 (rank : 53)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	75	Target Neighborhood Hits	71	Shared Neighborhood Hits	12
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.061674 (rank : 54)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	75	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
NC score	0.057653 (rank : 55)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	75	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

US6NL_HUMAN
NC score	0.035853 (rank : 56)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

EXOC3_MOUSE
NC score	0.029849 (rank : 57)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

BSN_HUMAN
NC score	0.028980 (rank : 58)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	1537	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

TBCD1_MOUSE
NC score	0.026576 (rank : 59)	θ value	0.0330416 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	241	Shared Neighborhood Hits	3
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

SON_HUMAN
NC score	0.022908 (rank : 60)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	1568	Shared Neighborhood Hits	22
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ARI1B_HUMAN
NC score	0.019895 (rank : 61)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	567	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

SCND1_HUMAN
NC score	0.019841 (rank : 62)	θ value	0.0193708 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	P57086	Gene names	SCAND1, SDP1
Domain Architecture
Description	SCAN domain-containing protein 1.

SC24C_HUMAN
NC score	0.018336 (rank : 63)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	662	Shared Neighborhood Hits	13
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CX045_HUMAN
NC score	0.017696 (rank : 64)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H5U8, Q5JXY9	Gene names	CXorf45
Domain Architecture	No domain graphic available
Description	Protein CXorf45.

EXOC3_HUMAN
NC score	0.016811 (rank : 65)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	O60645, Q8TEN6, Q8WUW0, Q96DI4	Gene names	EXOC3, SEC6, SEC6L1
Domain Architecture
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

DC12_HUMAN
NC score	0.014806 (rank : 66)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96FZ2, Q96G34, Q9NRP3	Gene names	C3orf37
Domain Architecture	No domain graphic available
Description	UPF0361 protein DC12.

OGFR_HUMAN
NC score	0.013208 (rank : 67)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	1582	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NRX2B_HUMAN
NC score	0.012492 (rank : 68)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	481	Shared Neighborhood Hits	7
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

JHD2B_MOUSE
NC score	0.011758 (rank : 69)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

DC1L2_MOUSE
NC score	0.011497 (rank : 70)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

NRIP1_HUMAN
NC score	0.010999 (rank : 71)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P48552, Q8IWE8	Gene names	NRIP1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

FOXO1_HUMAN
NC score	0.010705 (rank : 72)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

TAL1_HUMAN
NC score	0.010249 (rank : 73)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

NRX2A_HUMAN
NC score	0.008565 (rank : 74)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	614	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

MEF2B_HUMAN
NC score	0.007722 (rank : 75)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

MLL4_HUMAN
NC score	0.007450 (rank : 76)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	722	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SOX13_MOUSE
NC score	0.006911 (rank : 77)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	495	Shared Neighborhood Hits	6
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

HNF3B_MOUSE
NC score	0.006812 (rank : 78)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P35583, Q60602	Gene names	Foxa2, Hnf3b, Tcf-3b, Tcf3b
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

ZO1_HUMAN
NC score	0.006296 (rank : 79)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	474	Shared Neighborhood Hits	4
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ELF4_HUMAN
NC score	0.006212 (rank : 80)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

K0528_HUMAN
NC score	0.005960 (rank : 81)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

NFAC3_HUMAN
NC score	0.005620 (rank : 82)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

HNF3B_HUMAN
NC score	0.004527 (rank : 83)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y261, Q8WUW4, Q96DF7	Gene names	FOXA2, HNF3B, TCF3B
Domain Architecture
Description	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2).

SEPT9_HUMAN
NC score	0.003701 (rank : 84)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

LTB1S_HUMAN
NC score	0.003539 (rank : 85)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	502	Shared Neighborhood Hits	5
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.003521 (rank : 86)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	553	Shared Neighborhood Hits	5
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TLE1_MOUSE
NC score	0.000981 (rank : 87)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

HXB9_HUMAN
NC score	-0.000317 (rank : 88)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	344	Shared Neighborhood Hits	2
SwissProt Accessions	P17482, Q9H1I1	Gene names	HOXB9, HOX2E
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5).

GLIS1_HUMAN
NC score	-0.003242 (rank : 89)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	748	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

MAST3_HUMAN
NC score	-0.003696 (rank : 90)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	1128	Shared Neighborhood Hits	7
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).