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Network neighborhood for query Sequence : JHD2B_MOUSE

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JHD2B_MOUSE
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

JHD2A_HUMAN
θ value	0 (rank : 1)	NC score	0.964883 (rank : 3)
Query Neighborhood Hits	115	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2A_MOUSE
θ value	0 (rank : 2)	NC score	0.961143 (rank : 4)
Query Neighborhood Hits	115	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2B_HUMAN
θ value	0 (rank : 3)	NC score	0.982204 (rank : 2)
Query Neighborhood Hits	115	Target Neighborhood Hits	171	Shared Neighborhood Hits	44
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

JHD2B_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	115	Target Neighborhood Hits	115	Shared Neighborhood Hits	115
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

JHD2C_HUMAN
θ value	0 (rank : 5)	NC score	0.920536 (rank : 6)
Query Neighborhood Hits	115	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

JHD2C_MOUSE
θ value	0 (rank : 6)	NC score	0.928153 (rank : 5)
Query Neighborhood Hits	115	Target Neighborhood Hits	297	Shared Neighborhood Hits	20
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

HAIR_MOUSE
θ value	3.48949e-44 (rank : 7)	NC score	0.770438 (rank : 7)
Query Neighborhood Hits	115	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

HAIR_HUMAN
θ value	2.50074e-42 (rank : 8)	NC score	0.763630 (rank : 8)
Query Neighborhood Hits	115	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

SRRM2_MOUSE
θ value	0.0330416 (rank : 9)	NC score	0.082173 (rank : 9)
Query Neighborhood Hits	115	Target Neighborhood Hits	1470	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SALL1_HUMAN
θ value	0.0431538 (rank : 10)	NC score	0.007697 (rank : 93)
Query Neighborhood Hits	115	Target Neighborhood Hits	821	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

MFRP_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.022651 (rank : 39)
Query Neighborhood Hits	115	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

IWS1_HUMAN
θ value	0.0736092 (rank : 12)	NC score	0.056243 (rank : 11)
Query Neighborhood Hits	115	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PDXL2_HUMAN
θ value	0.163984 (rank : 13)	NC score	0.050590 (rank : 12)
Query Neighborhood Hits	115	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

SRRM2_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.075892 (rank : 10)
Query Neighborhood Hits	115	Target Neighborhood Hits	1296	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

UB2J1_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.036875 (rank : 21)
Query Neighborhood Hits	115	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

AFF4_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.049791 (rank : 13)
Query Neighborhood Hits	115	Target Neighborhood Hits	611	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

TARA_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.029186 (rank : 30)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

INSM1_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.019611 (rank : 46)
Query Neighborhood Hits	115	Target Neighborhood Hits	678	Shared Neighborhood Hits	8
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

PCLO_MOUSE
θ value	0.365318 (rank : 19)	NC score	0.029988 (rank : 28)
Query Neighborhood Hits	115	Target Neighborhood Hits	2275	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SF3B1_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.043999 (rank : 16)
Query Neighborhood Hits	115	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.365318 (rank : 21)	NC score	0.043979 (rank : 17)
Query Neighborhood Hits	115	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

TGBR3_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.037140 (rank : 20)
Query Neighborhood Hits	115	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

CUTL2_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.015870 (rank : 57)
Query Neighborhood Hits	115	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DOCK4_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.026919 (rank : 34)
Query Neighborhood Hits	115	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

UBP2L_MOUSE
θ value	0.62314 (rank : 25)	NC score	0.034836 (rank : 25)
Query Neighborhood Hits	115	Target Neighborhood Hits	173	Shared Neighborhood Hits	14
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

ADCY3_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.016832 (rank : 56)
Query Neighborhood Hits	115	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	O60266, Q9UDB1	Gene names	ADCY3, KIAA0511
Domain Architecture
Description	Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III) (Adenylate cyclase, olfactive type) (ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3).

HXD11_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.008577 (rank : 89)
Query Neighborhood Hits	115	Target Neighborhood Hits	353	Shared Neighborhood Hits	8
SwissProt Accessions	P31277, Q9NS02	Gene names	HOXD11, HOX4F
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4F).

MCR_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.015061 (rank : 61)
Query Neighborhood Hits	115	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PKHF1_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.041583 (rank : 18)
Query Neighborhood Hits	115	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

AFF1_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.049478 (rank : 14)
Query Neighborhood Hits	115	Target Neighborhood Hits	506	Shared Neighborhood Hits	27
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

FANCJ_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.022298 (rank : 40)
Query Neighborhood Hits	115	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

PKHF1_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.040609 (rank : 19)
Query Neighborhood Hits	115	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

UBP31_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.022763 (rank : 38)
Query Neighborhood Hits	115	Target Neighborhood Hits	293	Shared Neighborhood Hits	16
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

ANKS6_MOUSE
θ value	1.38821 (rank : 34)	NC score	0.012299 (rank : 68)
Query Neighborhood Hits	115	Target Neighborhood Hits	435	Shared Neighborhood Hits	9
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ARHGF_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.017178 (rank : 52)
Query Neighborhood Hits	115	Target Neighborhood Hits	214	Shared Neighborhood Hits	15
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

NCOA2_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.024238 (rank : 37)
Query Neighborhood Hits	115	Target Neighborhood Hits	281	Shared Neighborhood Hits	14
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

PARM1_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.032344 (rank : 26)
Query Neighborhood Hits	115	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

CAC1F_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.007413 (rank : 95)
Query Neighborhood Hits	115	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

MUCDL_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.014844 (rank : 62)
Query Neighborhood Hits	115	Target Neighborhood Hits	461	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PTPRA_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.005800 (rank : 99)
Query Neighborhood Hits	115	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

SIM2_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.011758 (rank : 73)
Query Neighborhood Hits	115	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

TRIO_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.000991 (rank : 113)
Query Neighborhood Hits	115	Target Neighborhood Hits	1580	Shared Neighborhood Hits	20
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

GP158_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.019767 (rank : 45)
Query Neighborhood Hits	115	Target Neighborhood Hits	221	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

IWS1_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.027293 (rank : 33)
Query Neighborhood Hits	115	Target Neighborhood Hits	1258	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LAP2A_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.027835 (rank : 32)
Query Neighborhood Hits	115	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

PO4F2_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.011247 (rank : 79)
Query Neighborhood Hits	115	Target Neighborhood Hits	310	Shared Neighborhood Hits	7
SwissProt Accessions	Q12837, Q13883, Q14987	Gene names	POU4F2, BRN3B
Domain Architecture
Description	POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brn-3B).

PO4F2_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.011222 (rank : 80)
Query Neighborhood Hits	115	Target Neighborhood Hits	312	Shared Neighborhood Hits	7
SwissProt Accessions	Q63934, Q63954	Gene names	Pou4f2, Brn3b
Domain Architecture
Description	POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brn-3B) (Brn-3.2).

AP180_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.015331 (rank : 59)
Query Neighborhood Hits	115	Target Neighborhood Hits	183	Shared Neighborhood Hits	11
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

BRDT_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.009040 (rank : 88)
Query Neighborhood Hits	115	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

FOXM1_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.011356 (rank : 76)
Query Neighborhood Hits	115	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

GLI3_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.005953 (rank : 98)
Query Neighborhood Hits	115	Target Neighborhood Hits	871	Shared Neighborhood Hits	14
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

MAP1A_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.014202 (rank : 66)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	30
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MCPH1_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.036348 (rank : 22)
Query Neighborhood Hits	115	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

NU153_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.029287 (rank : 29)
Query Neighborhood Hits	115	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

PDE11_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.006320 (rank : 97)
Query Neighborhood Hits	115	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P0C1Q2	Gene names	Pde11a
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

PEX19_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.019595 (rank : 47)
Query Neighborhood Hits	115	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCI5, Q8CEE1, Q921H0, Q9CZC1, Q9QUQ1	Gene names	Pex19, Pxf
Domain Architecture	No domain graphic available
Description	Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein) (PxF).

SQSTM_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.017799 (rank : 50)
Query Neighborhood Hits	115	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q13501, Q13446, Q9BUV7, Q9BVS6, Q9UEU1	Gene names	SQSTM1, ORCA
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (EBI3-associated protein of 60 kDa) (p60) (EBIAP).

ARAF_MOUSE
θ value	4.03905 (rank : 58)	NC score	-0.001089 (rank : 115)
Query Neighborhood Hits	115	Target Neighborhood Hits	874	Shared Neighborhood Hits	4
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

BASP_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.036149 (rank : 24)
Query Neighborhood Hits	115	Target Neighborhood Hits	321	Shared Neighborhood Hits	24
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CN155_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.018956 (rank : 48)
Query Neighborhood Hits	115	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CSPG2_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.004690 (rank : 102)
Query Neighborhood Hits	115	Target Neighborhood Hits	711	Shared Neighborhood Hits	11
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DVL1_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.007852 (rank : 92)
Query Neighborhood Hits	115	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

GP152_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.010879 (rank : 81)
Query Neighborhood Hits	115	Target Neighborhood Hits	607	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

HXA5_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.004530 (rank : 104)
Query Neighborhood Hits	115	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	P20719, O43367, Q96CY6	Gene names	HOXA5, HOX1C
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1C).

ITCH_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.005204 (rank : 101)
Query Neighborhood Hits	115	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

LTBP2_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.002263 (rank : 111)
Query Neighborhood Hits	115	Target Neighborhood Hits	617	Shared Neighborhood Hits	8
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PER3_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.012222 (rank : 70)
Query Neighborhood Hits	115	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

REPS1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.011768 (rank : 72)
Query Neighborhood Hits	115	Target Neighborhood Hits	205	Shared Neighborhood Hits	11
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RP1L1_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.016981 (rank : 54)
Query Neighborhood Hits	115	Target Neighborhood Hits	1072	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

STON2_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.028287 (rank : 31)
Query Neighborhood Hits	115	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

ABCAD_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.004123 (rank : 105)
Query Neighborhood Hits	115	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

APC_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.047012 (rank : 15)
Query Neighborhood Hits	115	Target Neighborhood Hits	441	Shared Neighborhood Hits	19
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

DAB2_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.021787 (rank : 41)
Query Neighborhood Hits	115	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

GLI3_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.003829 (rank : 106)
Query Neighborhood Hits	115	Target Neighborhood Hits	807	Shared Neighborhood Hits	11
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

K1802_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.011868 (rank : 71)
Query Neighborhood Hits	115	Target Neighborhood Hits	1596	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAML3_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.014788 (rank : 63)
Query Neighborhood Hits	115	Target Neighborhood Hits	323	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MINT_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.016837 (rank : 55)
Query Neighborhood Hits	115	Target Neighborhood Hits	1514	Shared Neighborhood Hits	40
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NEST_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.015259 (rank : 60)
Query Neighborhood Hits	115	Target Neighborhood Hits	1305	Shared Neighborhood Hits	25
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

RBGPR_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.011679 (rank : 74)
Query Neighborhood Hits	115	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2M9, O75872, Q9HAB0, Q9UFJ7, Q9UQ15	Gene names	RAB3GAP2, KIAA0839
Domain Architecture	No domain graphic available
Description	Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase- activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP regulatory subunit) (RAB3-GAP150) (RGAP-iso).

RUSC1_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.009245 (rank : 87)
Query Neighborhood Hits	115	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SPAG8_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.021526 (rank : 42)
Query Neighborhood Hits	115	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

TCF20_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.031174 (rank : 27)
Query Neighborhood Hits	115	Target Neighborhood Hits	323	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.036209 (rank : 23)
Query Neighborhood Hits	115	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

ZN509_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.003434 (rank : 108)
Query Neighborhood Hits	115	Target Neighborhood Hits	990	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

AF17_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.008190 (rank : 91)
Query Neighborhood Hits	115	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

EXO1_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.011558 (rank : 75)
Query Neighborhood Hits	115	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

GOGA3_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.002990 (rank : 110)
Query Neighborhood Hits	115	Target Neighborhood Hits	1437	Shared Neighborhood Hits	11
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

HXD3_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.003229 (rank : 109)
Query Neighborhood Hits	115	Target Neighborhood Hits	433	Shared Neighborhood Hits	8
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

MKRN3_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.010028 (rank : 83)
Query Neighborhood Hits	115	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

NCOA2_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.017407 (rank : 51)
Query Neighborhood Hits	115	Target Neighborhood Hits	281	Shared Neighborhood Hits	15
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PRGC2_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.010732 (rank : 82)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RAI1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.017819 (rank : 49)
Query Neighborhood Hits	115	Target Neighborhood Hits	360	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SP6_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.000445 (rank : 114)
Query Neighborhood Hits	115	Target Neighborhood Hits	700	Shared Neighborhood Hits	8
SwissProt Accessions	Q3SY56	Gene names	SP6, KLF14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14).

STIM1_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.008575 (rank : 90)
Query Neighborhood Hits	115	Target Neighborhood Hits	665	Shared Neighborhood Hits	7
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TR150_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.011262 (rank : 78)
Query Neighborhood Hits	115	Target Neighborhood Hits	468	Shared Neighborhood Hits	16
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRIPC_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.017147 (rank : 53)
Query Neighborhood Hits	115	Target Neighborhood Hits	319	Shared Neighborhood Hits	15
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

UB2J1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.020672 (rank : 43)
Query Neighborhood Hits	115	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

UBP2L_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.025375 (rank : 35)
Query Neighborhood Hits	115	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

XYLT1_MOUSE
θ value	6.88961 (rank : 99)	NC score	0.009374 (rank : 86)
Query Neighborhood Hits	115	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q811B1, Q9EPL1	Gene names	Xylt1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (Peptide O- xylosyltransferase 1).

ZN516_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.001365 (rank : 112)
Query Neighborhood Hits	115	Target Neighborhood Hits	854	Shared Neighborhood Hits	16
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

ZN750_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.025209 (rank : 36)
Query Neighborhood Hits	115	Target Neighborhood Hits	346	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ADRM1_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.014629 (rank : 64)
Query Neighborhood Hits	115	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

ADRM1_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.015430 (rank : 58)
Query Neighborhood Hits	115	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

ASXL1_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.012248 (rank : 69)
Query Neighborhood Hits	115	Target Neighborhood Hits	182	Shared Neighborhood Hits	8
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CAC1H_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.005294 (rank : 100)
Query Neighborhood Hits	115	Target Neighborhood Hits	307	Shared Neighborhood Hits	9
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

DSCL1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.003590 (rank : 107)
Query Neighborhood Hits	115	Target Neighborhood Hits	589	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

MDC1_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.020627 (rank : 44)
Query Neighborhood Hits	115	Target Neighborhood Hits	998	Shared Neighborhood Hits	44
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NCOA1_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.014542 (rank : 65)
Query Neighborhood Hits	115	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

PCOC1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.007492 (rank : 94)
Query Neighborhood Hits	115	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PDK4_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.004611 (rank : 103)
Query Neighborhood Hits	115	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q16654	Gene names	PDK4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

PER3_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.011350 (rank : 77)
Query Neighborhood Hits	115	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PKHD1_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.009492 (rank : 84)
Query Neighborhood Hits	115	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TCZ9	Gene names	PKHD1, FCYT, TIGM1
Domain Architecture
Description	Polycystic kidney and hepatic disease 1 precursor (Fibrocystin) (Polyductin) (Tigmin).

PTPRN_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.007170 (rank : 96)
Query Neighborhood Hits	115	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

SYMPK_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.012877 (rank : 67)
Query Neighborhood Hits	115	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

UBP18_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.009442 (rank : 85)
Query Neighborhood Hits	115	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

Hits sorted by NC score

JHD2B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	115	Target Neighborhood Hits	115	Shared Neighborhood Hits	115
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

JHD2B_HUMAN
NC score	0.982204 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	115	Target Neighborhood Hits	171	Shared Neighborhood Hits	44
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

JHD2A_HUMAN
NC score	0.964883 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	115	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2A_MOUSE
NC score	0.961143 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	115	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2C_MOUSE
NC score	0.928153 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	115	Target Neighborhood Hits	297	Shared Neighborhood Hits	20
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

JHD2C_HUMAN
NC score	0.920536 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	115	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

HAIR_MOUSE
NC score	0.770438 (rank : 7)	θ value	3.48949e-44 (rank : 7)
Query Neighborhood Hits	115	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

HAIR_HUMAN
NC score	0.763630 (rank : 8)	θ value	2.50074e-42 (rank : 8)
Query Neighborhood Hits	115	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

SRRM2_MOUSE
NC score	0.082173 (rank : 9)	θ value	0.0330416 (rank : 9)
Query Neighborhood Hits	115	Target Neighborhood Hits	1470	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM2_HUMAN
NC score	0.075892 (rank : 10)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	115	Target Neighborhood Hits	1296	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

IWS1_HUMAN
NC score	0.056243 (rank : 11)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	115	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PDXL2_HUMAN
NC score	0.050590 (rank : 12)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	115	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

AFF4_HUMAN
NC score	0.049791 (rank : 13)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	115	Target Neighborhood Hits	611	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF1_HUMAN
NC score	0.049478 (rank : 14)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	115	Target Neighborhood Hits	506	Shared Neighborhood Hits	27
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

APC_MOUSE
NC score	0.047012 (rank : 15)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	115	Target Neighborhood Hits	441	Shared Neighborhood Hits	19
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

SF3B1_HUMAN
NC score	0.043999 (rank : 16)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	115	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.043979 (rank : 17)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	115	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

PKHF1_HUMAN
NC score	0.041583 (rank : 18)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	115	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
NC score	0.040609 (rank : 19)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	115	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

TGBR3_HUMAN
NC score	0.037140 (rank : 20)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	115	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

UB2J1_HUMAN
NC score	0.036875 (rank : 21)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	115	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

MCPH1_MOUSE
NC score	0.036348 (rank : 22)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	115	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

TCF20_MOUSE
NC score	0.036209 (rank : 23)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	115	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

BASP_HUMAN
NC score	0.036149 (rank : 24)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	115	Target Neighborhood Hits	321	Shared Neighborhood Hits	24
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

UBP2L_MOUSE
NC score	0.034836 (rank : 25)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	115	Target Neighborhood Hits	173	Shared Neighborhood Hits	14
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

PARM1_HUMAN
NC score	0.032344 (rank : 26)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	115	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

TCF20_HUMAN
NC score	0.031174 (rank : 27)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	115	Target Neighborhood Hits	323	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

PCLO_MOUSE
NC score	0.029988 (rank : 28)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	115	Target Neighborhood Hits	2275	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NU153_HUMAN
NC score	0.029287 (rank : 29)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	115	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

TARA_HUMAN
NC score	0.029186 (rank : 30)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

STON2_MOUSE
NC score	0.028287 (rank : 31)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	115	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

LAP2A_HUMAN
NC score	0.027835 (rank : 32)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	115	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

IWS1_MOUSE
NC score	0.027293 (rank : 33)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	115	Target Neighborhood Hits	1258	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DOCK4_MOUSE
NC score	0.026919 (rank : 34)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	115	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

UBP2L_HUMAN
NC score	0.025375 (rank : 35)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	115	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

ZN750_MOUSE
NC score	0.025209 (rank : 36)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	115	Target Neighborhood Hits	346	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

NCOA2_MOUSE
NC score	0.024238 (rank : 37)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	115	Target Neighborhood Hits	281	Shared Neighborhood Hits	14
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

UBP31_HUMAN
NC score	0.022763 (rank : 38)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	115	Target Neighborhood Hits	293	Shared Neighborhood Hits	16
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

MFRP_HUMAN
NC score	0.022651 (rank : 39)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	115	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

FANCJ_HUMAN
NC score	0.022298 (rank : 40)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	115	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

DAB2_HUMAN
NC score	0.021787 (rank : 41)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	115	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

SPAG8_HUMAN
NC score	0.021526 (rank : 42)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	115	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

UB2J1_MOUSE
NC score	0.020672 (rank : 43)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	115	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

MDC1_MOUSE
NC score	0.020627 (rank : 44)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	115	Target Neighborhood Hits	998	Shared Neighborhood Hits	44
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

GP158_HUMAN
NC score	0.019767 (rank : 45)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	115	Target Neighborhood Hits	221	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

INSM1_MOUSE
NC score	0.019611 (rank : 46)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	115	Target Neighborhood Hits	678	Shared Neighborhood Hits	8
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

PEX19_MOUSE
NC score	0.019595 (rank : 47)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	115	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCI5, Q8CEE1, Q921H0, Q9CZC1, Q9QUQ1	Gene names	Pex19, Pxf
Domain Architecture	No domain graphic available
Description	Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein) (PxF).

CN155_HUMAN
NC score	0.018956 (rank : 48)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	115	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

RAI1_HUMAN
NC score	0.017819 (rank : 49)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	115	Target Neighborhood Hits	360	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SQSTM_HUMAN
NC score	0.017799 (rank : 50)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	115	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q13501, Q13446, Q9BUV7, Q9BVS6, Q9UEU1	Gene names	SQSTM1, ORCA
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (EBI3-associated protein of 60 kDa) (p60) (EBIAP).

NCOA2_HUMAN
NC score	0.017407 (rank : 51)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	115	Target Neighborhood Hits	281	Shared Neighborhood Hits	15
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

ARHGF_HUMAN
NC score	0.017178 (rank : 52)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	115	Target Neighborhood Hits	214	Shared Neighborhood Hits	15
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

TRIPC_HUMAN
NC score	0.017147 (rank : 53)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	115	Target Neighborhood Hits	319	Shared Neighborhood Hits	15
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

RP1L1_HUMAN
NC score	0.016981 (rank : 54)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	115	Target Neighborhood Hits	1072	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MINT_MOUSE
NC score	0.016837 (rank : 55)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	115	Target Neighborhood Hits	1514	Shared Neighborhood Hits	40
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ADCY3_HUMAN
NC score	0.016832 (rank : 56)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	115	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	O60266, Q9UDB1	Gene names	ADCY3, KIAA0511
Domain Architecture
Description	Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III) (Adenylate cyclase, olfactive type) (ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3).

CUTL2_HUMAN
NC score	0.015870 (rank : 57)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	115	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ADRM1_MOUSE
NC score	0.015430 (rank : 58)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	115	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

AP180_HUMAN
NC score	0.015331 (rank : 59)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	115	Target Neighborhood Hits	183	Shared Neighborhood Hits	11
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

NEST_HUMAN
NC score	0.015259 (rank : 60)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	115	Target Neighborhood Hits	1305	Shared Neighborhood Hits	25
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

MCR_MOUSE
NC score	0.015061 (rank : 61)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	115	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

MUCDL_MOUSE
NC score	0.014844 (rank : 62)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	115	Target Neighborhood Hits	461	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MAML3_HUMAN
NC score	0.014788 (rank : 63)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	115	Target Neighborhood Hits	323	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

ADRM1_HUMAN
NC score	0.014629 (rank : 64)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	115	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

NCOA1_HUMAN
NC score	0.014542 (rank : 65)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	115	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

MAP1A_HUMAN
NC score	0.014202 (rank : 66)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	30
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SYMPK_MOUSE
NC score	0.012877 (rank : 67)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	115	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

ANKS6_MOUSE
NC score	0.012299 (rank : 68)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	115	Target Neighborhood Hits	435	Shared Neighborhood Hits	9
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ASXL1_MOUSE
NC score	0.012248 (rank : 69)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	115	Target Neighborhood Hits	182	Shared Neighborhood Hits	8
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

PER3_MOUSE
NC score	0.012222 (rank : 70)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	115	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

K1802_MOUSE
NC score	0.011868 (rank : 71)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	115	Target Neighborhood Hits	1596	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

REPS1_HUMAN
NC score	0.011768 (rank : 72)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	115	Target Neighborhood Hits	205	Shared Neighborhood Hits	11
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SIM2_MOUSE
NC score	0.011758 (rank : 73)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	115	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

RBGPR_HUMAN
NC score	0.011679 (rank : 74)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	115	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2M9, O75872, Q9HAB0, Q9UFJ7, Q9UQ15	Gene names	RAB3GAP2, KIAA0839
Domain Architecture	No domain graphic available
Description	Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase- activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP regulatory subunit) (RAB3-GAP150) (RGAP-iso).

EXO1_MOUSE
NC score	0.011558 (rank : 75)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	115	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

FOXM1_HUMAN
NC score	0.011356 (rank : 76)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	115	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

PER3_HUMAN
NC score	0.011350 (rank : 77)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	115	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

TR150_MOUSE
NC score	0.011262 (rank : 78)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	115	Target Neighborhood Hits	468	Shared Neighborhood Hits	16
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

PO4F2_HUMAN
NC score	0.011247 (rank : 79)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	115	Target Neighborhood Hits	310	Shared Neighborhood Hits	7
SwissProt Accessions	Q12837, Q13883, Q14987	Gene names	POU4F2, BRN3B
Domain Architecture
Description	POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brn-3B).

PO4F2_MOUSE
NC score	0.011222 (rank : 80)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	115	Target Neighborhood Hits	312	Shared Neighborhood Hits	7
SwissProt Accessions	Q63934, Q63954	Gene names	Pou4f2, Brn3b
Domain Architecture
Description	POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brn-3B) (Brn-3.2).

GP152_MOUSE
NC score	0.010879 (rank : 81)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	115	Target Neighborhood Hits	607	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

PRGC2_MOUSE
NC score	0.010732 (rank : 82)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

MKRN3_HUMAN
NC score	0.010028 (rank : 83)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	115	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

PKHD1_HUMAN
NC score	0.009492 (rank : 84)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	115	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TCZ9	Gene names	PKHD1, FCYT, TIGM1
Domain Architecture
Description	Polycystic kidney and hepatic disease 1 precursor (Fibrocystin) (Polyductin) (Tigmin).

UBP18_MOUSE
NC score	0.009442 (rank : 85)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	115	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

XYLT1_MOUSE
NC score	0.009374 (rank : 86)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	115	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q811B1, Q9EPL1	Gene names	Xylt1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (Peptide O- xylosyltransferase 1).

RUSC1_HUMAN
NC score	0.009245 (rank : 87)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	115	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

BRDT_MOUSE
NC score	0.009040 (rank : 88)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	115	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

HXD11_HUMAN
NC score	0.008577 (rank : 89)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	115	Target Neighborhood Hits	353	Shared Neighborhood Hits	8
SwissProt Accessions	P31277, Q9NS02	Gene names	HOXD11, HOX4F
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4F).

STIM1_HUMAN
NC score	0.008575 (rank : 90)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	115	Target Neighborhood Hits	665	Shared Neighborhood Hits	7
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

AF17_HUMAN
NC score	0.008190 (rank : 91)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	115	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

DVL1_MOUSE
NC score	0.007852 (rank : 92)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	115	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

SALL1_HUMAN
NC score	0.007697 (rank : 93)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	115	Target Neighborhood Hits	821	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

PCOC1_HUMAN
NC score	0.007492 (rank : 94)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	115	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

CAC1F_HUMAN
NC score	0.007413 (rank : 95)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	115	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

PTPRN_HUMAN
NC score	0.007170 (rank : 96)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	115	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PDE11_MOUSE
NC score	0.006320 (rank : 97)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	115	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P0C1Q2	Gene names	Pde11a
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

GLI3_HUMAN
NC score	0.005953 (rank : 98)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	115	Target Neighborhood Hits	871	Shared Neighborhood Hits	14
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

PTPRA_HUMAN
NC score	0.005800 (rank : 99)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	115	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

CAC1H_HUMAN
NC score	0.005294 (rank : 100)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	115	Target Neighborhood Hits	307	Shared Neighborhood Hits	9
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

ITCH_HUMAN
NC score	0.005204 (rank : 101)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	115	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

CSPG2_MOUSE
NC score	0.004690 (rank : 102)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	115	Target Neighborhood Hits	711	Shared Neighborhood Hits	11
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

PDK4_HUMAN
NC score	0.004611 (rank : 103)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	115	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q16654	Gene names	PDK4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

HXA5_HUMAN
NC score	0.004530 (rank : 104)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	115	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	P20719, O43367, Q96CY6	Gene names	HOXA5, HOX1C
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1C).

ABCAD_MOUSE
NC score	0.004123 (rank : 105)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	115	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

GLI3_MOUSE
NC score	0.003829 (rank : 106)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	115	Target Neighborhood Hits	807	Shared Neighborhood Hits	11
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

DSCL1_HUMAN
NC score	0.003590 (rank : 107)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	115	Target Neighborhood Hits	589	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

ZN509_MOUSE
NC score	0.003434 (rank : 108)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	115	Target Neighborhood Hits	990	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

HXD3_HUMAN
NC score	0.003229 (rank : 109)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	115	Target Neighborhood Hits	433	Shared Neighborhood Hits	8
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

GOGA3_MOUSE
NC score	0.002990 (rank : 110)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	115	Target Neighborhood Hits	1437	Shared Neighborhood Hits	11
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

LTBP2_MOUSE
NC score	0.002263 (rank : 111)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	115	Target Neighborhood Hits	617	Shared Neighborhood Hits	8
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

ZN516_HUMAN
NC score	0.001365 (rank : 112)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	115	Target Neighborhood Hits	854	Shared Neighborhood Hits	16
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

TRIO_HUMAN
NC score	0.000991 (rank : 113)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	115	Target Neighborhood Hits	1580	Shared Neighborhood Hits	20
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

SP6_HUMAN
NC score	0.000445 (rank : 114)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	115	Target Neighborhood Hits	700	Shared Neighborhood Hits	8
SwissProt Accessions	Q3SY56	Gene names	SP6, KLF14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14).

ARAF_MOUSE
NC score	-0.001089 (rank : 115)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	115	Target Neighborhood Hits	874	Shared Neighborhood Hits	4
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).