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Network neighborhood for query Sequence : MCPH1_MOUSE

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MCPH1_MOUSE
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MCPH1_HUMAN
θ value	0 (rank : 1)	NC score	0.931552 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

MCPH1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

BRCA1_MOUSE
θ value	3.29651e-10 (rank : 3)	NC score	0.254805 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	436	Shared Neighborhood Hits	16
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BARD1_HUMAN
θ value	5.81887e-07 (rank : 4)	NC score	0.134793 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	427	Shared Neighborhood Hits	13
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	2.44474e-05 (rank : 5)	NC score	0.127981 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	411	Shared Neighborhood Hits	13
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BRCA1_HUMAN
θ value	7.1131e-05 (rank : 6)	NC score	0.209206 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	381	Shared Neighborhood Hits	13
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

LZTS1_MOUSE
θ value	0.00175202 (rank : 7)	NC score	0.068358 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	540	Shared Neighborhood Hits	23
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MDC1_MOUSE
θ value	0.00228821 (rank : 8)	NC score	0.108827 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	998	Shared Neighborhood Hits	34
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MDC1_HUMAN
θ value	0.00665767 (rank : 9)	NC score	0.093673 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	1446	Shared Neighborhood Hits	42
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CAC1E_MOUSE
θ value	0.00869519 (rank : 10)	NC score	0.043712 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SYTL3_MOUSE
θ value	0.0113563 (rank : 11)	NC score	0.057034 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

MUC1_MOUSE
θ value	0.0148317 (rank : 12)	NC score	0.088955 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	388	Shared Neighborhood Hits	17
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

TOPB1_HUMAN
θ value	0.0431538 (rank : 13)	NC score	0.149967 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

TOPB1_MOUSE
θ value	0.0736092 (rank : 14)	NC score	0.129130 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

UACA_MOUSE
θ value	0.0736092 (rank : 15)	NC score	0.040842 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	1620	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

SYTL2_MOUSE
θ value	0.0961366 (rank : 16)	NC score	0.042839 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	253	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SRCA_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.054361 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	380	Shared Neighborhood Hits	22
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

LMNB1_HUMAN
θ value	0.163984 (rank : 18)	NC score	0.042540 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	714	Shared Neighborhood Hits	26
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

CIR_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.081988 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	249	Shared Neighborhood Hits	13
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

DGKH_HUMAN
θ value	0.21417 (rank : 20)	NC score	0.030523 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	255	Shared Neighborhood Hits	3
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

SAPS3_MOUSE
θ value	0.21417 (rank : 21)	NC score	0.037141 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

ZCH10_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.093436 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

RGS3_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.033700 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	1621	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CAC1E_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.037723 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CENPK_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.057659 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	273	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

K1849_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.035833 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	220	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

POLI_MOUSE
θ value	0.365318 (rank : 27)	NC score	0.043857 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

ROCK2_HUMAN
θ value	0.365318 (rank : 28)	NC score	0.017255 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	2073	Shared Neighborhood Hits	37
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

U383_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.053012 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYL2	Gene names	C4orf23
Domain Architecture	No domain graphic available
Description	Putative methyltransferase UPF0383 (EC 2.1.1.-).

IWS1_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.052107 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	1241	Shared Neighborhood Hits	35
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LMNB1_MOUSE
θ value	0.47712 (rank : 31)	NC score	0.039989 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	719	Shared Neighborhood Hits	24
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

RP1L1_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.050861 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	1072	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ELOA1_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.035882 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	388	Shared Neighborhood Hits	16
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

HOOK3_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.042316 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	1070	Shared Neighborhood Hits	24
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

XE7_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.044050 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	738	Shared Neighborhood Hits	27
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

OPHN1_MOUSE
θ value	0.813845 (rank : 36)	NC score	0.022146 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

T22D4_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.035749 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	403	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TTBK2_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.019401 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	811	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

CENPC_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.041939 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

DUS8_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.020969 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

ETV1_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.018041 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

SOS2_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.024076 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

EHMT1_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.030257 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	417	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

HOOK1_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.042319 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	910	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

JHD2C_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.040141 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	297	Shared Neighborhood Hits	16
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

MANS1_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.043145 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR33, Q80V71	Gene names	Mansc1
Domain Architecture	No domain graphic available
Description	MANSC domain-containing protein 1 precursor.

UBXD2_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.034269 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	241	Shared Neighborhood Hits	6
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

CT043_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.038050 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY42, Q9BYL7, Q9HCV9, Q9NX29, Q9NZZ8, Q9P002, Q9UHW3	Gene names	C20orf43
Domain Architecture
Description	Uncharacterized protein C20orf43.

HOOK1_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.040904 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	942	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK3_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.040202 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	1007	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

IWS1_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.047558 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	1258	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RAI14_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.036559 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	1505	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SYCP1_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.029816 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	1313	Shared Neighborhood Hits	28
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TSH3_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.016576 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	564	Shared Neighborhood Hits	3
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

JHD2B_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.038611 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

LUZP1_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.033092 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	739	Shared Neighborhood Hits	31
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MAST4_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.009750 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	1804	Shared Neighborhood Hits	38
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MTR1L_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.005913 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	1180	Shared Neighborhood Hits	14
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

MUCDL_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.029475 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	777	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NRG2_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.017579 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

PF21B_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.024464 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

RAI14_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.034495 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	1367	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ZFHX2_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.014988 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	1178	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

GLI2_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.001952 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	971	Shared Neighborhood Hits	9
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

GNAS1_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.011894 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

HUWE1_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.019723 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	443	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

JHD2B_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.036348 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	115	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

K0310_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.036734 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	420	Shared Neighborhood Hits	12
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MAP2_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.026312 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	342	Shared Neighborhood Hits	14
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MKL1_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.022675 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MYO5C_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.018609 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	1206	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

CF152_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.033253 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	704	Shared Neighborhood Hits	21
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CI082_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.028794 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

E41L1_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.014980 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

FILA_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.028203 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	685	Shared Neighborhood Hits	23
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

KTNA1_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.009229 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

MAP4_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.039175 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	409	Shared Neighborhood Hits	14
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MTMR3_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.024091 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

NEST_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.026095 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	1305	Shared Neighborhood Hits	37
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PDZD2_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.026399 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	772	Shared Neighborhood Hits	28
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PHAR3_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.024226 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PHC3_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.021562 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

SYN1_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.024186 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	363	Shared Neighborhood Hits	13
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TTBK2_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.017089 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	822	Shared Neighborhood Hits	17
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

CN145_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.028589 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	916	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

E41L1_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.014258 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

FOXP4_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.008800 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

NU153_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.028883 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

ROCK2_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.015569 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	2072	Shared Neighborhood Hits	38
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

SETB1_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.019218 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SYT14_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.015848 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

ALO17_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.029420 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	317	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ANC1_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.016144 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

ANKS6_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.026913 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	435	Shared Neighborhood Hits	14
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

E2AK4_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.005169 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	984	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

FYV1_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.012117 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

PPR3A_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.018402 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	54	Shared Neighborhood Hits	6
SwissProt Accessions	Q16821, O43476, Q75LN8, Q7KYM8, Q86UI6	Gene names	PPP1R3A, PP1G
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit).

SARDH_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.013558 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UL12, Q9Y280, Q9Y2Y3	Gene names	SARDH
Domain Architecture	No domain graphic available
Description	Sarcosine dehydrogenase, mitochondrial precursor (EC 1.5.99.1) (SarDH) (BPR-2).

TAF6_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.025207 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

CN004_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.018340 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

CP2B6_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.002293 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	P20813, Q2V565, Q9UK46	Gene names	CYP2B6
Domain Architecture
Description	Cytochrome P450 2B6 (EC 1.14.14.1) (CYPIIB6) (P450 IIB1).

DMD_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.016551 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	1135	Shared Neighborhood Hits	26
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DNJC1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.009365 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KC8	Gene names	DNAJC1
Domain Architecture
Description	DnaJ homolog subfamily C member 1.

MYLK2_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.003460 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	920	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

NIPBL_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.037539 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	1311	Shared Neighborhood Hits	43
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.037341 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	1041	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RBMS2_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.009890 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	Q15434	Gene names	RBMS2, SCR3
Domain Architecture	No domain graphic available
Description	RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3).

RBMS2_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.009842 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VC70	Gene names	Rbms2
Domain Architecture	No domain graphic available
Description	RNA-binding motif, single-stranded-interacting protein 2.

SEM6B_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.004491 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SMCA4_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.007702 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	597	Shared Neighborhood Hits	17
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMG7_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.014686 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

STK31_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.011652 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	570	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

TAOK3_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.005826 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	1494	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

THOC2_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.050216 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	337	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

UBP31_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.018782 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

ZBTB3_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.000503 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	792	Shared Neighborhood Hits	5
SwissProt Accessions	Q91X45, Q8BIJ4	Gene names	Zbtb3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

Hits sorted by NC score

MCPH1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MCPH1_HUMAN
NC score	0.931552 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

BRCA1_MOUSE
NC score	0.254805 (rank : 3)	θ value	3.29651e-10 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	436	Shared Neighborhood Hits	16
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRCA1_HUMAN
NC score	0.209206 (rank : 4)	θ value	7.1131e-05 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	381	Shared Neighborhood Hits	13
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TOPB1_HUMAN
NC score	0.149967 (rank : 5)	θ value	0.0431538 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

BARD1_HUMAN
NC score	0.134793 (rank : 6)	θ value	5.81887e-07 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	427	Shared Neighborhood Hits	13
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

TOPB1_MOUSE
NC score	0.129130 (rank : 7)	θ value	0.0736092 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

BARD1_MOUSE
NC score	0.127981 (rank : 8)	θ value	2.44474e-05 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	411	Shared Neighborhood Hits	13
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

MDC1_MOUSE
NC score	0.108827 (rank : 9)	θ value	0.00228821 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	998	Shared Neighborhood Hits	34
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MDC1_HUMAN
NC score	0.093673 (rank : 10)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	1446	Shared Neighborhood Hits	42
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ZCH10_MOUSE
NC score	0.093436 (rank : 11)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

MUC1_MOUSE
NC score	0.088955 (rank : 12)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	388	Shared Neighborhood Hits	17
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CIR_HUMAN
NC score	0.081988 (rank : 13)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	249	Shared Neighborhood Hits	13
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

LZTS1_MOUSE
NC score	0.068358 (rank : 14)	θ value	0.00175202 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	540	Shared Neighborhood Hits	23
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

CENPK_HUMAN
NC score	0.057659 (rank : 15)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	273	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

SYTL3_MOUSE
NC score	0.057034 (rank : 16)	θ value	0.0113563 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SRCA_HUMAN
NC score	0.054361 (rank : 17)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	380	Shared Neighborhood Hits	22
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

U383_HUMAN
NC score	0.053012 (rank : 18)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYL2	Gene names	C4orf23
Domain Architecture	No domain graphic available
Description	Putative methyltransferase UPF0383 (EC 2.1.1.-).

IWS1_HUMAN
NC score	0.052107 (rank : 19)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	1241	Shared Neighborhood Hits	35
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RP1L1_HUMAN
NC score	0.050861 (rank : 20)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	1072	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

THOC2_HUMAN
NC score	0.050216 (rank : 21)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	337	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

IWS1_MOUSE
NC score	0.047558 (rank : 22)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	1258	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

XE7_HUMAN
NC score	0.044050 (rank : 23)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	738	Shared Neighborhood Hits	27
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

POLI_MOUSE
NC score	0.043857 (rank : 24)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

CAC1E_MOUSE
NC score	0.043712 (rank : 25)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

MANS1_MOUSE
NC score	0.043145 (rank : 26)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR33, Q80V71	Gene names	Mansc1
Domain Architecture	No domain graphic available
Description	MANSC domain-containing protein 1 precursor.

SYTL2_MOUSE
NC score	0.042839 (rank : 27)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	253	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

LMNB1_HUMAN
NC score	0.042540 (rank : 28)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	714	Shared Neighborhood Hits	26
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

HOOK1_MOUSE
NC score	0.042319 (rank : 29)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	910	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK3_HUMAN
NC score	0.042316 (rank : 30)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	1070	Shared Neighborhood Hits	24
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

CENPC_HUMAN
NC score	0.041939 (rank : 31)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

HOOK1_HUMAN
NC score	0.040904 (rank : 32)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	942	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

UACA_MOUSE
NC score	0.040842 (rank : 33)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	1620	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

HOOK3_MOUSE
NC score	0.040202 (rank : 34)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	1007	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

JHD2C_MOUSE
NC score	0.040141 (rank : 35)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	297	Shared Neighborhood Hits	16
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

LMNB1_MOUSE
NC score	0.039989 (rank : 36)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	719	Shared Neighborhood Hits	24
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

MAP4_MOUSE
NC score	0.039175 (rank : 37)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	409	Shared Neighborhood Hits	14
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

JHD2B_HUMAN
NC score	0.038611 (rank : 38)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

CT043_HUMAN
NC score	0.038050 (rank : 39)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY42, Q9BYL7, Q9HCV9, Q9NX29, Q9NZZ8, Q9P002, Q9UHW3	Gene names	C20orf43
Domain Architecture
Description	Uncharacterized protein C20orf43.

CAC1E_HUMAN
NC score	0.037723 (rank : 40)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

NIPBL_HUMAN
NC score	0.037539 (rank : 41)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	1311	Shared Neighborhood Hits	43
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
NC score	0.037341 (rank : 42)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	1041	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SAPS3_MOUSE
NC score	0.037141 (rank : 43)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

K0310_HUMAN
NC score	0.036734 (rank : 44)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	420	Shared Neighborhood Hits	12
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

RAI14_MOUSE
NC score	0.036559 (rank : 45)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	1505	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

JHD2B_MOUSE
NC score	0.036348 (rank : 46)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	115	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

ELOA1_HUMAN
NC score	0.035882 (rank : 47)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	388	Shared Neighborhood Hits	16
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

K1849_HUMAN
NC score	0.035833 (rank : 48)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	220	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

T22D4_HUMAN
NC score	0.035749 (rank : 49)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	403	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

RAI14_HUMAN
NC score	0.034495 (rank : 50)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	1367	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

UBXD2_HUMAN
NC score	0.034269 (rank : 51)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	241	Shared Neighborhood Hits	6
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

RGS3_MOUSE
NC score	0.033700 (rank : 52)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	1621	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CF152_HUMAN
NC score	0.033253 (rank : 53)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	704	Shared Neighborhood Hits	21
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

LUZP1_HUMAN
NC score	0.033092 (rank : 54)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	739	Shared Neighborhood Hits	31
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

DGKH_HUMAN
NC score	0.030523 (rank : 55)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	255	Shared Neighborhood Hits	3
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

EHMT1_HUMAN
NC score	0.030257 (rank : 56)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	417	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SYCP1_HUMAN
NC score	0.029816 (rank : 57)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	1313	Shared Neighborhood Hits	28
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

MUCDL_HUMAN
NC score	0.029475 (rank : 58)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	777	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ALO17_HUMAN
NC score	0.029420 (rank : 59)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	317	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

NU153_HUMAN
NC score	0.028883 (rank : 60)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

CI082_HUMAN
NC score	0.028794 (rank : 61)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

CN145_MOUSE
NC score	0.028589 (rank : 62)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	916	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

FILA_HUMAN
NC score	0.028203 (rank : 63)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	685	Shared Neighborhood Hits	23
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

ANKS6_MOUSE
NC score	0.026913 (rank : 64)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	435	Shared Neighborhood Hits	14
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

PDZD2_HUMAN
NC score	0.026399 (rank : 65)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	772	Shared Neighborhood Hits	28
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

MAP2_MOUSE
NC score	0.026312 (rank : 66)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	342	Shared Neighborhood Hits	14
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

NEST_HUMAN
NC score	0.026095 (rank : 67)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	1305	Shared Neighborhood Hits	37
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

TAF6_HUMAN
NC score	0.025207 (rank : 68)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

PF21B_HUMAN
NC score	0.024464 (rank : 69)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHAR3_MOUSE
NC score	0.024226 (rank : 70)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

SYN1_MOUSE
NC score	0.024186 (rank : 71)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	363	Shared Neighborhood Hits	13
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

MTMR3_HUMAN
NC score	0.024091 (rank : 72)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

SOS2_HUMAN
NC score	0.024076 (rank : 73)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

MKL1_HUMAN
NC score	0.022675 (rank : 74)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

OPHN1_MOUSE
NC score	0.022146 (rank : 75)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

PHC3_HUMAN
NC score	0.021562 (rank : 76)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

DUS8_MOUSE
NC score	0.020969 (rank : 77)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

HUWE1_HUMAN
NC score	0.019723 (rank : 78)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	443	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

TTBK2_MOUSE
NC score	0.019401 (rank : 79)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	811	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

SETB1_MOUSE
NC score	0.019218 (rank : 80)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

UBP31_HUMAN
NC score	0.018782 (rank : 81)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

MYO5C_HUMAN
NC score	0.018609 (rank : 82)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	1206	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

PPR3A_HUMAN
NC score	0.018402 (rank : 83)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	54	Shared Neighborhood Hits	6
SwissProt Accessions	Q16821, O43476, Q75LN8, Q7KYM8, Q86UI6	Gene names	PPP1R3A, PP1G
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit).

CN004_MOUSE
NC score	0.018340 (rank : 84)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

ETV1_HUMAN
NC score	0.018041 (rank : 85)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

NRG2_HUMAN
NC score	0.017579 (rank : 86)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

ROCK2_HUMAN
NC score	0.017255 (rank : 87)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	2073	Shared Neighborhood Hits	37
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

TTBK2_HUMAN
NC score	0.017089 (rank : 88)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	822	Shared Neighborhood Hits	17
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

TSH3_HUMAN
NC score	0.016576 (rank : 89)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	564	Shared Neighborhood Hits	3
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

DMD_HUMAN
NC score	0.016551 (rank : 90)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	1135	Shared Neighborhood Hits	26
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

ANC1_MOUSE
NC score	0.016144 (rank : 91)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

SYT14_MOUSE
NC score	0.015848 (rank : 92)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

ROCK2_MOUSE
NC score	0.015569 (rank : 93)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	2072	Shared Neighborhood Hits	38
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

ZFHX2_HUMAN
NC score	0.014988 (rank : 94)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	1178	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

E41L1_HUMAN
NC score	0.014980 (rank : 95)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

SMG7_MOUSE
NC score	0.014686 (rank : 96)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

E41L1_MOUSE
NC score	0.014258 (rank : 97)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

SARDH_HUMAN
NC score	0.013558 (rank : 98)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UL12, Q9Y280, Q9Y2Y3	Gene names	SARDH
Domain Architecture	No domain graphic available
Description	Sarcosine dehydrogenase, mitochondrial precursor (EC 1.5.99.1) (SarDH) (BPR-2).

FYV1_HUMAN
NC score	0.012117 (rank : 99)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

GNAS1_HUMAN
NC score	0.011894 (rank : 100)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

STK31_HUMAN
NC score	0.011652 (rank : 101)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	570	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

RBMS2_HUMAN
NC score	0.009890 (rank : 102)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	Q15434	Gene names	RBMS2, SCR3
Domain Architecture	No domain graphic available
Description	RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3).

RBMS2_MOUSE
NC score	0.009842 (rank : 103)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VC70	Gene names	Rbms2
Domain Architecture	No domain graphic available
Description	RNA-binding motif, single-stranded-interacting protein 2.

MAST4_HUMAN
NC score	0.009750 (rank : 104)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	1804	Shared Neighborhood Hits	38
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

DNJC1_HUMAN
NC score	0.009365 (rank : 105)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KC8	Gene names	DNAJC1
Domain Architecture
Description	DnaJ homolog subfamily C member 1.

KTNA1_HUMAN
NC score	0.009229 (rank : 106)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

FOXP4_HUMAN
NC score	0.008800 (rank : 107)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

SMCA4_HUMAN
NC score	0.007702 (rank : 108)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	597	Shared Neighborhood Hits	17
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

MTR1L_HUMAN
NC score	0.005913 (rank : 109)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	1180	Shared Neighborhood Hits	14
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

TAOK3_HUMAN
NC score	0.005826 (rank : 110)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	1494	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

E2AK4_MOUSE
NC score	0.005169 (rank : 111)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	984	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

SEM6B_MOUSE
NC score	0.004491 (rank : 112)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

MYLK2_HUMAN
NC score	0.003460 (rank : 113)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	920	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

CP2B6_HUMAN
NC score	0.002293 (rank : 114)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	P20813, Q2V565, Q9UK46	Gene names	CYP2B6
Domain Architecture
Description	Cytochrome P450 2B6 (EC 1.14.14.1) (CYPIIB6) (P450 IIB1).

GLI2_HUMAN
NC score	0.001952 (rank : 115)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	971	Shared Neighborhood Hits	9
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

ZBTB3_MOUSE
NC score	0.000503 (rank : 116)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	792	Shared Neighborhood Hits	5
SwissProt Accessions	Q91X45, Q8BIJ4	Gene names	Zbtb3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.