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Network neighborhood for query Sequence : E41L1_HUMAN

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E41L1_HUMAN
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

E41L1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	180	Target Neighborhood Hits	180	Shared Neighborhood Hits	180
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_MOUSE
θ value	0 (rank : 2)	NC score	0.992845 (rank : 2)
Query Neighborhood Hits	180	Target Neighborhood Hits	106	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L3_MOUSE
θ value	0 (rank : 3)	NC score	0.973723 (rank : 5)
Query Neighborhood Hits	180	Target Neighborhood Hits	250	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
θ value	2.74423e-182 (rank : 4)	NC score	0.968879 (rank : 7)
Query Neighborhood Hits	180	Target Neighborhood Hits	287	Shared Neighborhood Hits	70
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
θ value	9.76035e-180 (rank : 5)	NC score	0.954202 (rank : 11)
Query Neighborhood Hits	180	Target Neighborhood Hits	459	Shared Neighborhood Hits	102
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L3_HUMAN
θ value	1.72287e-176 (rank : 6)	NC score	0.980953 (rank : 3)
Query Neighborhood Hits	180	Target Neighborhood Hits	113	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

41_HUMAN
θ value	1.01709e-152 (rank : 7)	NC score	0.975047 (rank : 4)
Query Neighborhood Hits	180	Target Neighborhood Hits	157	Shared Neighborhood Hits	61
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

41_MOUSE
θ value	1.12453e-151 (rank : 8)	NC score	0.973177 (rank : 6)
Query Neighborhood Hits	180	Target Neighborhood Hits	184	Shared Neighborhood Hits	60
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

PTN4_HUMAN
θ value	8.77142e-88 (rank : 9)	NC score	0.673892 (rank : 32)
Query Neighborhood Hits	180	Target Neighborhood Hits	303	Shared Neighborhood Hits	53
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

E41L5_HUMAN
θ value	7.70199e-76 (rank : 10)	NC score	0.958107 (rank : 8)
Query Neighborhood Hits	180	Target Neighborhood Hits	76	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
θ value	8.81223e-72 (rank : 11)	NC score	0.956881 (rank : 9)
Query Neighborhood Hits	180	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41LB_HUMAN
θ value	1.27248e-70 (rank : 12)	NC score	0.950926 (rank : 15)
Query Neighborhood Hits	180	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41LA_HUMAN
θ value	4.09345e-69 (rank : 13)	NC score	0.952151 (rank : 13)
Query Neighborhood Hits	180	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FARP1_HUMAN
θ value	4.52582e-68 (rank : 14)	NC score	0.793650 (rank : 18)
Query Neighborhood Hits	180	Target Neighborhood Hits	241	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FRMD5_HUMAN
θ value	7.71989e-68 (rank : 15)	NC score	0.954008 (rank : 12)
Query Neighborhood Hits	180	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_MOUSE
θ value	1.00825e-67 (rank : 16)	NC score	0.956449 (rank : 10)
Query Neighborhood Hits	180	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LA_MOUSE
θ value	1.45591e-66 (rank : 17)	NC score	0.951948 (rank : 14)
Query Neighborhood Hits	180	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FARP2_MOUSE
θ value	9.43692e-66 (rank : 18)	NC score	0.761267 (rank : 26)
Query Neighborhood Hits	180	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_HUMAN
θ value	5.17823e-64 (rank : 19)	NC score	0.769471 (rank : 25)
Query Neighborhood Hits	180	Target Neighborhood Hits	240	Shared Neighborhood Hits	52
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTN3_HUMAN
θ value	1.45929e-58 (rank : 20)	NC score	0.644706 (rank : 36)
Query Neighborhood Hits	180	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN21_MOUSE
θ value	6.37413e-38 (rank : 21)	NC score	0.615658 (rank : 38)
Query Neighborhood Hits	180	Target Neighborhood Hits	155	Shared Neighborhood Hits	51
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
θ value	3.16345e-37 (rank : 22)	NC score	0.613809 (rank : 39)
Query Neighborhood Hits	180	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

EZRI_HUMAN
θ value	2.67802e-36 (rank : 23)	NC score	0.739997 (rank : 27)
Query Neighborhood Hits	180	Target Neighborhood Hits	663	Shared Neighborhood Hits	76
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	3.4976e-36 (rank : 24)	NC score	0.735685 (rank : 28)
Query Neighborhood Hits	180	Target Neighborhood Hits	693	Shared Neighborhood Hits	79
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

MOES_MOUSE
θ value	5.0505e-35 (rank : 25)	NC score	0.670271 (rank : 33)
Query Neighborhood Hits	180	Target Neighborhood Hits	923	Shared Neighborhood Hits	78
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
θ value	1.9192e-34 (rank : 26)	NC score	0.677928 (rank : 31)
Query Neighborhood Hits	180	Target Neighborhood Hits	892	Shared Neighborhood Hits	80
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

RADI_HUMAN
θ value	1.24399e-33 (rank : 27)	NC score	0.719187 (rank : 29)
Query Neighborhood Hits	180	Target Neighborhood Hits	741	Shared Neighborhood Hits	78
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	1.24399e-33 (rank : 28)	NC score	0.715286 (rank : 30)
Query Neighborhood Hits	180	Target Neighborhood Hits	773	Shared Neighborhood Hits	77
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MERL_HUMAN
θ value	8.06329e-33 (rank : 29)	NC score	0.773359 (rank : 24)
Query Neighborhood Hits	180	Target Neighborhood Hits	532	Shared Neighborhood Hits	73
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	1.0531e-32 (rank : 30)	NC score	0.773654 (rank : 23)
Query Neighborhood Hits	180	Target Neighborhood Hits	524	Shared Neighborhood Hits	71
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PTN14_MOUSE
θ value	8.91499e-32 (rank : 31)	NC score	0.595867 (rank : 40)
Query Neighborhood Hits	180	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
θ value	2.86786e-30 (rank : 32)	NC score	0.588047 (rank : 41)
Query Neighborhood Hits	180	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

MYLIP_HUMAN
θ value	1.02001e-27 (rank : 33)	NC score	0.838209 (rank : 17)
Query Neighborhood Hits	180	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_MOUSE
θ value	2.27234e-27 (rank : 34)	NC score	0.853416 (rank : 16)
Query Neighborhood Hits	180	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PTN13_HUMAN
θ value	1.92365e-26 (rank : 35)	NC score	0.470713 (rank : 43)
Query Neighborhood Hits	180	Target Neighborhood Hits	471	Shared Neighborhood Hits	62
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	8.08199e-25 (rank : 36)	NC score	0.478903 (rank : 42)
Query Neighborhood Hits	180	Target Neighborhood Hits	426	Shared Neighborhood Hits	52
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

FRM4B_HUMAN
θ value	2.35151e-24 (rank : 37)	NC score	0.790524 (rank : 19)
Query Neighborhood Hits	180	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
θ value	3.07116e-24 (rank : 38)	NC score	0.787868 (rank : 20)
Query Neighborhood Hits	180	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
θ value	4.43474e-23 (rank : 39)	NC score	0.779443 (rank : 21)
Query Neighborhood Hits	180	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
θ value	7.56453e-23 (rank : 40)	NC score	0.778024 (rank : 22)
Query Neighborhood Hits	180	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

TLN2_HUMAN
θ value	9.59137e-10 (rank : 41)	NC score	0.415217 (rank : 47)
Query Neighborhood Hits	180	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	1.63604e-09 (rank : 42)	NC score	0.419273 (rank : 45)
Query Neighborhood Hits	180	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

FRMD6_HUMAN
θ value	3.64472e-09 (rank : 43)	NC score	0.654441 (rank : 35)
Query Neighborhood Hits	180	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD1_HUMAN
θ value	1.06045e-08 (rank : 44)	NC score	0.641709 (rank : 37)
Query Neighborhood Hits	180	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

FRMD6_MOUSE
θ value	1.38499e-08 (rank : 45)	NC score	0.662636 (rank : 34)
Query Neighborhood Hits	180	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

TLN1_HUMAN
θ value	4.0297e-08 (rank : 46)	NC score	0.421475 (rank : 44)
Query Neighborhood Hits	180	Target Neighborhood Hits	218	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	4.0297e-08 (rank : 47)	NC score	0.418270 (rank : 46)
Query Neighborhood Hits	180	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

THOC2_HUMAN
θ value	0.00228821 (rank : 48)	NC score	0.061660 (rank : 113)
Query Neighborhood Hits	180	Target Neighborhood Hits	337	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

GIT1_MOUSE
θ value	0.00298849 (rank : 49)	NC score	0.032747 (rank : 174)
Query Neighborhood Hits	180	Target Neighborhood Hits	341	Shared Neighborhood Hits	12
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

CD2L2_HUMAN
θ value	0.0148317 (rank : 50)	NC score	0.007167 (rank : 248)
Query Neighborhood Hits	180	Target Neighborhood Hits	1439	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CN145_HUMAN
θ value	0.0148317 (rank : 51)	NC score	0.046146 (rank : 148)
Query Neighborhood Hits	180	Target Neighborhood Hits	1196	Shared Neighborhood Hits	60
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

HTSF1_MOUSE
θ value	0.0148317 (rank : 52)	NC score	0.048044 (rank : 146)
Query Neighborhood Hits	180	Target Neighborhood Hits	425	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

IWS1_HUMAN
θ value	0.0252991 (rank : 53)	NC score	0.068461 (rank : 103)
Query Neighborhood Hits	180	Target Neighborhood Hits	1241	Shared Neighborhood Hits	104
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ZC313_HUMAN
θ value	0.0330416 (rank : 54)	NC score	0.064214 (rank : 110)
Query Neighborhood Hits	180	Target Neighborhood Hits	772	Shared Neighborhood Hits	73
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

COHA1_MOUSE
θ value	0.0431538 (rank : 55)	NC score	0.012062 (rank : 239)
Query Neighborhood Hits	180	Target Neighborhood Hits	414	Shared Neighborhood Hits	10
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DDX46_MOUSE
θ value	0.0431538 (rank : 56)	NC score	0.016159 (rank : 227)
Query Neighborhood Hits	180	Target Neighborhood Hits	358	Shared Neighborhood Hits	31
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DNMT1_HUMAN
θ value	0.0431538 (rank : 57)	NC score	0.052192 (rank : 135)
Query Neighborhood Hits	180	Target Neighborhood Hits	401	Shared Neighborhood Hits	49
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

CD2L1_HUMAN
θ value	0.0563607 (rank : 58)	NC score	0.007035 (rank : 249)
Query Neighborhood Hits	180	Target Neighborhood Hits	1467	Shared Neighborhood Hits	49
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

KIF3A_MOUSE
θ value	0.0563607 (rank : 59)	NC score	0.031397 (rank : 180)
Query Neighborhood Hits	180	Target Neighborhood Hits	715	Shared Neighborhood Hits	45
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

TRDN_HUMAN
θ value	0.0563607 (rank : 60)	NC score	0.050321 (rank : 140)
Query Neighborhood Hits	180	Target Neighborhood Hits	542	Shared Neighborhood Hits	32
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

GIT1_HUMAN
θ value	0.0736092 (rank : 61)	NC score	0.026048 (rank : 194)
Query Neighborhood Hits	180	Target Neighborhood Hits	336	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

KIF3B_HUMAN
θ value	0.0736092 (rank : 62)	NC score	0.015214 (rank : 230)
Query Neighborhood Hits	180	Target Neighborhood Hits	540	Shared Neighborhood Hits	24
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

PPIG_HUMAN
θ value	0.0736092 (rank : 63)	NC score	0.024704 (rank : 203)
Query Neighborhood Hits	180	Target Neighborhood Hits	670	Shared Neighborhood Hits	65
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

CN145_MOUSE
θ value	0.0961366 (rank : 64)	NC score	0.038623 (rank : 162)
Query Neighborhood Hits	180	Target Neighborhood Hits	916	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

KIF3B_MOUSE
θ value	0.0961366 (rank : 65)	NC score	0.015181 (rank : 231)
Query Neighborhood Hits	180	Target Neighborhood Hits	533	Shared Neighborhood Hits	24
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

US6NL_MOUSE
θ value	0.0961366 (rank : 66)	NC score	0.030271 (rank : 184)
Query Neighborhood Hits	180	Target Neighborhood Hits	157	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

IF3A_HUMAN
θ value	0.125558 (rank : 67)	NC score	0.042065 (rank : 155)
Query Neighborhood Hits	180	Target Neighborhood Hits	875	Shared Neighborhood Hits	60
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

NIPBL_HUMAN
θ value	0.125558 (rank : 68)	NC score	0.070546 (rank : 101)
Query Neighborhood Hits	180	Target Neighborhood Hits	1311	Shared Neighborhood Hits	106
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

DDX46_HUMAN
θ value	0.163984 (rank : 69)	NC score	0.014353 (rank : 233)
Query Neighborhood Hits	180	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

TP53B_HUMAN
θ value	0.163984 (rank : 70)	NC score	0.037908 (rank : 164)
Query Neighborhood Hits	180	Target Neighborhood Hits	413	Shared Neighborhood Hits	38
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

NCKX1_HUMAN
θ value	0.21417 (rank : 71)	NC score	0.025985 (rank : 196)
Query Neighborhood Hits	180	Target Neighborhood Hits	223	Shared Neighborhood Hits	19
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

NFH_MOUSE
θ value	0.21417 (rank : 72)	NC score	0.028543 (rank : 186)
Query Neighborhood Hits	180	Target Neighborhood Hits	2247	Shared Neighborhood Hits	83
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NSBP1_MOUSE
θ value	0.21417 (rank : 73)	NC score	0.045859 (rank : 149)
Query Neighborhood Hits	180	Target Neighborhood Hits	681	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

AVEN_MOUSE
θ value	0.279714 (rank : 74)	NC score	0.026590 (rank : 193)
Query Neighborhood Hits	180	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D9K3	Gene names	Aven
Domain Architecture	No domain graphic available
Description	Cell death regulator Aven.

MDC1_HUMAN
θ value	0.279714 (rank : 75)	NC score	0.035873 (rank : 167)
Query Neighborhood Hits	180	Target Neighborhood Hits	1446	Shared Neighborhood Hits	85
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NNP1_MOUSE
θ value	0.279714 (rank : 76)	NC score	0.022236 (rank : 208)
Query Neighborhood Hits	180	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

SFR12_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.040548 (rank : 157)
Query Neighborhood Hits	180	Target Neighborhood Hits	553	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

ACINU_HUMAN
θ value	0.365318 (rank : 78)	NC score	0.057451 (rank : 124)
Query Neighborhood Hits	180	Target Neighborhood Hits	828	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

PCLO_MOUSE
θ value	0.365318 (rank : 79)	NC score	0.026043 (rank : 195)
Query Neighborhood Hits	180	Target Neighborhood Hits	2275	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PPRB_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.027374 (rank : 190)
Query Neighborhood Hits	180	Target Neighborhood Hits	311	Shared Neighborhood Hits	18
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

RBM6_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.042729 (rank : 154)
Query Neighborhood Hits	180	Target Neighborhood Hits	221	Shared Neighborhood Hits	27
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

SFR12_MOUSE
θ value	0.365318 (rank : 82)	NC score	0.038662 (rank : 161)
Query Neighborhood Hits	180	Target Neighborhood Hits	486	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SFRS4_MOUSE
θ value	0.365318 (rank : 83)	NC score	0.023106 (rank : 206)
Query Neighborhood Hits	180	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

BAZ2B_HUMAN
θ value	0.47712 (rank : 84)	NC score	0.025737 (rank : 198)
Query Neighborhood Hits	180	Target Neighborhood Hits	803	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

NUCL_MOUSE
θ value	0.47712 (rank : 85)	NC score	0.019771 (rank : 212)
Query Neighborhood Hits	180	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

LIPS_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.031130 (rank : 182)
Query Neighborhood Hits	180	Target Neighborhood Hits	314	Shared Neighborhood Hits	21
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MDN1_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.042852 (rank : 153)
Query Neighborhood Hits	180	Target Neighborhood Hits	662	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MYH10_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.018832 (rank : 216)
Query Neighborhood Hits	180	Target Neighborhood Hits	1620	Shared Neighborhood Hits	64
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.018946 (rank : 215)
Query Neighborhood Hits	180	Target Neighborhood Hits	1612	Shared Neighborhood Hits	66
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RBBP6_HUMAN
θ value	0.62314 (rank : 90)	NC score	0.050195 (rank : 141)
Query Neighborhood Hits	180	Target Neighborhood Hits	1135	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TCP10_HUMAN
θ value	0.62314 (rank : 91)	NC score	0.034887 (rank : 169)
Query Neighborhood Hits	180	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

IF3A_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.039627 (rank : 158)
Query Neighborhood Hits	180	Target Neighborhood Hits	871	Shared Neighborhood Hits	60
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

K1143_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.043441 (rank : 151)
Query Neighborhood Hits	180	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AT1, Q96HJ8, Q9ULS7	Gene names	KIAA1143
Domain Architecture	No domain graphic available
Description	Protein KIAA1143.

NPBL_MOUSE
θ value	0.813845 (rank : 94)	NC score	0.070003 (rank : 102)
Query Neighborhood Hits	180	Target Neighborhood Hits	1041	Shared Neighborhood Hits	89
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TGON2_MOUSE
θ value	0.813845 (rank : 95)	NC score	0.037583 (rank : 166)
Query Neighborhood Hits	180	Target Neighborhood Hits	277	Shared Neighborhood Hits	41
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

CTR9_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.035326 (rank : 168)
Query Neighborhood Hits	180	Target Neighborhood Hits	383	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CUTL2_HUMAN
θ value	1.06291 (rank : 97)	NC score	0.030514 (rank : 183)
Query Neighborhood Hits	180	Target Neighborhood Hits	906	Shared Neighborhood Hits	38
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

HMGN3_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.027255 (rank : 191)
Query Neighborhood Hits	180	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q15651, Q7RTT0, Q969M5, Q9BZT7	Gene names	HMGN3, TRIP7
Domain Architecture	No domain graphic available
Description	High mobility group nucleosome-binding domain-containing protein 3 (Thyroid receptor-interacting protein 7) (TRIP7).

KIF3A_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.028262 (rank : 187)
Query Neighborhood Hits	180	Target Neighborhood Hits	704	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MYST4_HUMAN
θ value	1.06291 (rank : 100)	NC score	0.033391 (rank : 171)
Query Neighborhood Hits	180	Target Neighborhood Hits	671	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PCLO_HUMAN
θ value	1.06291 (rank : 101)	NC score	0.023501 (rank : 205)
Query Neighborhood Hits	180	Target Neighborhood Hits	2046	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RENT2_HUMAN
θ value	1.06291 (rank : 102)	NC score	0.049068 (rank : 145)
Query Neighborhood Hits	180	Target Neighborhood Hits	618	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SFR17_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.047376 (rank : 147)
Query Neighborhood Hits	180	Target Neighborhood Hits	325	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

THSD1_MOUSE
θ value	1.06291 (rank : 104)	NC score	0.018592 (rank : 218)
Query Neighborhood Hits	180	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

WDR60_HUMAN
θ value	1.06291 (rank : 105)	NC score	0.024471 (rank : 204)
Query Neighborhood Hits	180	Target Neighborhood Hits	286	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

BEGIN_MOUSE
θ value	1.38821 (rank : 106)	NC score	0.032148 (rank : 177)
Query Neighborhood Hits	180	Target Neighborhood Hits	383	Shared Neighborhood Hits	26
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BRD7_MOUSE
θ value	1.38821 (rank : 107)	NC score	0.019056 (rank : 214)
Query Neighborhood Hits	180	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

TRHY_HUMAN
θ value	1.38821 (rank : 108)	NC score	0.027224 (rank : 192)
Query Neighborhood Hits	180	Target Neighborhood Hits	1385	Shared Neighborhood Hits	62
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

NFM_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.031990 (rank : 178)
Query Neighborhood Hits	180	Target Neighborhood Hits	1328	Shared Neighborhood Hits	72
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PER3_MOUSE
θ value	1.81305 (rank : 110)	NC score	0.007540 (rank : 246)
Query Neighborhood Hits	180	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

ACINU_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.032297 (rank : 176)
Query Neighborhood Hits	180	Target Neighborhood Hits	712	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CCD55_HUMAN
θ value	2.36792 (rank : 112)	NC score	0.037896 (rank : 165)
Query Neighborhood Hits	180	Target Neighborhood Hits	513	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

GEMI5_MOUSE
θ value	2.36792 (rank : 113)	NC score	0.008320 (rank : 243)
Query Neighborhood Hits	180	Target Neighborhood Hits	424	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

K1143_MOUSE
θ value	2.36792 (rank : 114)	NC score	0.043548 (rank : 150)
Query Neighborhood Hits	180	Target Neighborhood Hits	48	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

NFM_MOUSE
θ value	2.36792 (rank : 115)	NC score	0.031347 (rank : 181)
Query Neighborhood Hits	180	Target Neighborhood Hits	1159	Shared Neighborhood Hits	70
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

REN3B_HUMAN
θ value	2.36792 (rank : 116)	NC score	0.018181 (rank : 219)
Query Neighborhood Hits	180	Target Neighborhood Hits	412	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

BMS1_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.014329 (rank : 234)
Query Neighborhood Hits	180	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

CHIC1_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.018138 (rank : 220)
Query Neighborhood Hits	180	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CBW7, O08904, Q8K3S5	Gene names	Chic1, Brx
Domain Architecture	No domain graphic available
Description	Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein).

IWS1_MOUSE
θ value	3.0926 (rank : 119)	NC score	0.066695 (rank : 105)
Query Neighborhood Hits	180	Target Neighborhood Hits	1258	Shared Neighborhood Hits	101
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MINT_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.039487 (rank : 159)
Query Neighborhood Hits	180	Target Neighborhood Hits	1291	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MINT_MOUSE
θ value	3.0926 (rank : 121)	NC score	0.038849 (rank : 160)
Query Neighborhood Hits	180	Target Neighborhood Hits	1514	Shared Neighborhood Hits	76
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYO5C_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.025425 (rank : 200)
Query Neighborhood Hits	180	Target Neighborhood Hits	1206	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

SFRS4_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.021734 (rank : 209)
Query Neighborhood Hits	180	Target Neighborhood Hits	384	Shared Neighborhood Hits	30
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

AP3B1_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.012406 (rank : 238)
Query Neighborhood Hits	180	Target Neighborhood Hits	283	Shared Neighborhood Hits	21
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CAN3_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.004466 (rank : 252)
Query Neighborhood Hits	180	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CHD2_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.007267 (rank : 247)
Query Neighborhood Hits	180	Target Neighborhood Hits	360	Shared Neighborhood Hits	24
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CTR9_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.025942 (rank : 197)
Query Neighborhood Hits	180	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

DDX21_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.016527 (rank : 226)
Query Neighborhood Hits	180	Target Neighborhood Hits	308	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

GOGA4_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.032725 (rank : 175)
Query Neighborhood Hits	180	Target Neighborhood Hits	1939	Shared Neighborhood Hits	88
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MCPH1_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.014980 (rank : 232)
Query Neighborhood Hits	180	Target Neighborhood Hits	116	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

NFH_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.025645 (rank : 199)
Query Neighborhood Hits	180	Target Neighborhood Hits	1242	Shared Neighborhood Hits	60
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

REXO1_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.012504 (rank : 237)
Query Neighborhood Hits	180	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RU17_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.018692 (rank : 217)
Query Neighborhood Hits	180	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

ANR18_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.016893 (rank : 223)
Query Neighborhood Hits	180	Target Neighborhood Hits	1106	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

BEGIN_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.024708 (rank : 202)
Query Neighborhood Hits	180	Target Neighborhood Hits	454	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BRD8_MOUSE
θ value	5.27518 (rank : 136)	NC score	0.016849 (rank : 224)
Query Neighborhood Hits	180	Target Neighborhood Hits	422	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRE1A_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.019823 (rank : 211)
Query Neighborhood Hits	180	Target Neighborhood Hits	1071	Shared Neighborhood Hits	48
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CTCF_MOUSE
θ value	5.27518 (rank : 138)	NC score	-0.005912 (rank : 264)
Query Neighborhood Hits	180	Target Neighborhood Hits	796	Shared Neighborhood Hits	12
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

CUTL2_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.016091 (rank : 228)
Query Neighborhood Hits	180	Target Neighborhood Hits	771	Shared Neighborhood Hits	31
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

IASPP_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.004802 (rank : 251)
Query Neighborhood Hits	180	Target Neighborhood Hits	688	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF38_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.015263 (rank : 229)
Query Neighborhood Hits	180	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

MLL3_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.017411 (rank : 222)
Query Neighborhood Hits	180	Target Neighborhood Hits	1644	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PHF14_MOUSE
θ value	5.27518 (rank : 143)	NC score	0.017518 (rank : 221)
Query Neighborhood Hits	180	Target Neighborhood Hits	342	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

RBM25_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.041643 (rank : 156)
Query Neighborhood Hits	180	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RU17_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.016597 (rank : 225)
Query Neighborhood Hits	180	Target Neighborhood Hits	278	Shared Neighborhood Hits	19
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

TEX14_HUMAN
θ value	5.27518 (rank : 146)	NC score	0.004243 (rank : 253)
Query Neighborhood Hits	180	Target Neighborhood Hits	1103	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TGON1_MOUSE
θ value	5.27518 (rank : 147)	NC score	0.049664 (rank : 144)
Query Neighborhood Hits	180	Target Neighborhood Hits	243	Shared Neighborhood Hits	36
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TTC19_HUMAN
θ value	5.27518 (rank : 148)	NC score	0.007620 (rank : 245)
Query Neighborhood Hits	180	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q6DKK2, Q7L3U8, Q9NXB2	Gene names	TTC19
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 19 (TPR repeat protein 19).

3BP2_MOUSE
θ value	6.88961 (rank : 149)	NC score	0.027557 (rank : 189)
Query Neighborhood Hits	180	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ABTAP_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.020452 (rank : 210)
Query Neighborhood Hits	180	Target Neighborhood Hits	381	Shared Neighborhood Hits	31
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

BRD7_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.010999 (rank : 242)
Query Neighborhood Hits	180	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

DMP1_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.057743 (rank : 122)
Query Neighborhood Hits	180	Target Neighborhood Hits	491	Shared Neighborhood Hits	53
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DNJC9_HUMAN
θ value	6.88961 (rank : 153)	NC score	0.002908 (rank : 256)
Query Neighborhood Hits	180	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXX5	Gene names	DNAJC9
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 9 (DnaJ protein SB73).

HMGB2_MOUSE
θ value	6.88961 (rank : 154)	NC score	0.002395 (rank : 258)
Query Neighborhood Hits	180	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

ITSN1_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.038585 (rank : 163)
Query Neighborhood Hits	180	Target Neighborhood Hits	1757	Shared Neighborhood Hits	71
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.043159 (rank : 152)
Query Neighborhood Hits	180	Target Neighborhood Hits	1669	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MK04_MOUSE
θ value	6.88961 (rank : 157)	NC score	-0.003585 (rank : 262)
Query Neighborhood Hits	180	Target Neighborhood Hits	852	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5G0	Gene names	Mapk4, Erk4, Prkm4
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4).

NDF2_MOUSE
θ value	6.88961 (rank : 158)	NC score	0.002106 (rank : 259)
Query Neighborhood Hits	180	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

PTMS_MOUSE
θ value	6.88961 (rank : 159)	NC score	0.032873 (rank : 173)
Query Neighborhood Hits	180	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

SETD2_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.012562 (rank : 236)
Query Neighborhood Hits	180	Target Neighborhood Hits	412	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SMBT1_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.003750 (rank : 254)
Query Neighborhood Hits	180	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JMD1, Q6NZD3, Q8CFS1	Gene names	Sfmbt1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1.

AF9_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.022870 (rank : 207)
Query Neighborhood Hits	180	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CD34_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.006689 (rank : 250)
Query Neighborhood Hits	180	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q64314, Q62550, Q62551	Gene names	Cd34
Domain Architecture
Description	Hematopoietic progenitor cell antigen CD34 precursor.

DDX51_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.008034 (rank : 244)
Query Neighborhood Hits	180	Target Neighborhood Hits	332	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DEK_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.033870 (rank : 170)
Query Neighborhood Hits	180	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DHX36_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.002687 (rank : 257)
Query Neighborhood Hits	180	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

HGS_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.001827 (rank : 260)
Query Neighborhood Hits	180	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HTSF1_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.027594 (rank : 188)
Query Neighborhood Hits	180	Target Neighborhood Hits	408	Shared Neighborhood Hits	24
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

IF2P_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.029257 (rank : 185)
Query Neighborhood Hits	180	Target Neighborhood Hits	889	Shared Neighborhood Hits	49
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

LR37B_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.000645 (rank : 261)
Query Neighborhood Hits	180	Target Neighborhood Hits	392	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MLL3_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.019094 (rank : 213)
Query Neighborhood Hits	180	Target Neighborhood Hits	1399	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYPT1_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.011922 (rank : 240)
Query Neighborhood Hits	180	Target Neighborhood Hits	723	Shared Neighborhood Hits	51
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYT1_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.013720 (rank : 235)
Query Neighborhood Hits	180	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

NEK4_MOUSE
θ value	8.99809 (rank : 174)	NC score	-0.005226 (rank : 263)
Query Neighborhood Hits	180	Target Neighborhood Hits	899	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

NOL3_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.011643 (rank : 241)
Query Neighborhood Hits	180	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

PTPRG_MOUSE
θ value	8.99809 (rank : 176)	NC score	0.084352 (rank : 90)
Query Neighborhood Hits	180	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

RPGR1_MOUSE
θ value	8.99809 (rank : 177)	NC score	0.031897 (rank : 179)
Query Neighborhood Hits	180	Target Neighborhood Hits	713	Shared Neighborhood Hits	45
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SLY_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.003446 (rank : 255)
Query Neighborhood Hits	180	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

TXND2_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.033319 (rank : 172)
Query Neighborhood Hits	180	Target Neighborhood Hits	793	Shared Neighborhood Hits	60
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

UBF1_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.024952 (rank : 201)
Query Neighborhood Hits	180	Target Neighborhood Hits	419	Shared Neighborhood Hits	32
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

AKA12_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.066570 (rank : 106)
Query Neighborhood Hits	180	Target Neighborhood Hits	825	Shared Neighborhood Hits	80
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ARHG4_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.050340 (rank : 139)
Query Neighborhood Hits	180	Target Neighborhood Hits	185	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CA106_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.090186 (rank : 87)
Query Neighborhood Hits	180	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.088825 (rank : 88)
Query Neighborhood Hits	180	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CCD11_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.051286 (rank : 138)
Query Neighborhood Hits	180	Target Neighborhood Hits	822	Shared Neighborhood Hits	51
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CD45_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.097008 (rank : 82)
Query Neighborhood Hits	180	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.101701 (rank : 72)
Query Neighborhood Hits	180	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CT2NL_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.058624 (rank : 120)
Query Neighborhood Hits	180	Target Neighborhood Hits	1059	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.054461 (rank : 130)
Query Neighborhood Hits	180	Target Neighborhood Hits	902	Shared Neighborhood Hits	71
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FGD1_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.057449 (rank : 125)
Query Neighborhood Hits	180	Target Neighborhood Hits	367	Shared Neighborhood Hits	18
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.055773 (rank : 128)
Query Neighborhood Hits	180	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.053063 (rank : 133)
Query Neighborhood Hits	180	Target Neighborhood Hits	163	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.051739 (rank : 136)
Query Neighborhood Hits	180	Target Neighborhood Hits	249	Shared Neighborhood Hits	10
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.050052 (rank : 143)
Query Neighborhood Hits	180	Target Neighborhood Hits	257	Shared Neighborhood Hits	8
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.058568 (rank : 121)
Query Neighborhood Hits	180	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.058989 (rank : 119)
Query Neighborhood Hits	180	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD5_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.061395 (rank : 114)
Query Neighborhood Hits	180	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.057608 (rank : 123)
Query Neighborhood Hits	180	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.060997 (rank : 115)
Query Neighborhood Hits	180	Target Neighborhood Hits	237	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.060738 (rank : 117)
Query Neighborhood Hits	180	Target Neighborhood Hits	282	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

HIP1R_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.060808 (rank : 116)
Query Neighborhood Hits	180	Target Neighborhood Hits	809	Shared Neighborhood Hits	48
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.060590 (rank : 118)
Query Neighborhood Hits	180	Target Neighborhood Hits	959	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.067030 (rank : 104)
Query Neighborhood Hits	180	Target Neighborhood Hits	1016	Shared Neighborhood Hits	57
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

KRIT1_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.083823 (rank : 92)
Query Neighborhood Hits	180	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.077410 (rank : 100)
Query Neighborhood Hits	180	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

LEO1_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.052891 (rank : 134)
Query Neighborhood Hits	180	Target Neighborhood Hits	958	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MAP1A_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.055801 (rank : 127)
Query Neighborhood Hits	180	Target Neighborhood Hits	1626	Shared Neighborhood Hits	93
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MESD1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.051641 (rank : 137)
Query Neighborhood Hits	180	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

MESD1_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.053103 (rank : 132)
Query Neighborhood Hits	180	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

NAF1_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.050114 (rank : 142)
Query Neighborhood Hits	180	Target Neighborhood Hits	937	Shared Neighborhood Hits	51
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NASP_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.064476 (rank : 108)
Query Neighborhood Hits	180	Target Neighborhood Hits	709	Shared Neighborhood Hits	70
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NOP14_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.055092 (rank : 129)
Query Neighborhood Hits	180	Target Neighborhood Hits	573	Shared Neighborhood Hits	63
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PKHA6_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.055963 (rank : 126)
Query Neighborhood Hits	180	Target Neighborhood Hits	591	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PTN11_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.099909 (rank : 78)
Query Neighborhood Hits	180	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.099918 (rank : 77)
Query Neighborhood Hits	180	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.106537 (rank : 61)
Query Neighborhood Hits	180	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.106537 (rank : 60)
Query Neighborhood Hits	180	Target Neighborhood Hits	123	Shared Neighborhood Hits	12
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN18_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.115249 (rank : 51)
Query Neighborhood Hits	180	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.111676 (rank : 53)
Query Neighborhood Hits	180	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.115173 (rank : 52)
Query Neighborhood Hits	180	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.115529 (rank : 49)
Query Neighborhood Hits	180	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.108775 (rank : 56)
Query Neighborhood Hits	180	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.107153 (rank : 58)
Query Neighborhood Hits	180	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.102547 (rank : 69)
Query Neighborhood Hits	180	Target Neighborhood Hits	646	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.100714 (rank : 73)
Query Neighborhood Hits	180	Target Neighborhood Hits	726	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.115432 (rank : 50)
Query Neighborhood Hits	180	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.117005 (rank : 48)
Query Neighborhood Hits	180	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN5_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.100112 (rank : 76)
Query Neighborhood Hits	180	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.100112 (rank : 75)
Query Neighborhood Hits	180	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.106284 (rank : 62)
Query Neighborhood Hits	180	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.106257 (rank : 63)
Query Neighborhood Hits	180	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.106670 (rank : 59)
Query Neighborhood Hits	180	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.107828 (rank : 57)
Query Neighborhood Hits	180	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.111337 (rank : 54)
Query Neighborhood Hits	180	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.110978 (rank : 55)
Query Neighborhood Hits	180	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.104633 (rank : 64)
Query Neighborhood Hits	180	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.104073 (rank : 67)
Query Neighborhood Hits	180	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.093114 (rank : 84)
Query Neighborhood Hits	180	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.093077 (rank : 85)
Query Neighborhood Hits	180	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRB_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.097762 (rank : 81)
Query Neighborhood Hits	180	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRD_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.064458 (rank : 109)
Query Neighborhood Hits	180	Target Neighborhood Hits	485	Shared Neighborhood Hits	12
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.061985 (rank : 112)
Query Neighborhood Hits	180	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.093469 (rank : 83)
Query Neighborhood Hits	180	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.092982 (rank : 86)
Query Neighborhood Hits	180	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRF_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.062754 (rank : 111)
Query Neighborhood Hits	180	Target Neighborhood Hits	489	Shared Neighborhood Hits	9
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.083733 (rank : 93)
Query Neighborhood Hits	180	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.099816 (rank : 79)
Query Neighborhood Hits	180	Target Neighborhood Hits	207	Shared Neighborhood Hits	11
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.100186 (rank : 74)
Query Neighborhood Hits	180	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.083694 (rank : 94)
Query Neighborhood Hits	180	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.084409 (rank : 89)
Query Neighborhood Hits	180	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.078680 (rank : 99)
Query Neighborhood Hits	180	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.079068 (rank : 97)
Query Neighborhood Hits	180	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.104330 (rank : 66)
Query Neighborhood Hits	180	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.103957 (rank : 68)
Query Neighborhood Hits	180	Target Neighborhood Hits	240	Shared Neighborhood Hits	12
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.104339 (rank : 65)
Query Neighborhood Hits	180	Target Neighborhood Hits	139	Shared Neighborhood Hits	9
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.101977 (rank : 71)
Query Neighborhood Hits	180	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.102312 (rank : 70)
Query Neighborhood Hits	180	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRS_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.065660 (rank : 107)
Query Neighborhood Hits	180	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRT_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.081009 (rank : 95)
Query Neighborhood Hits	180	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.080886 (rank : 96)
Query Neighborhood Hits	180	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.078791 (rank : 98)
Query Neighborhood Hits	180	Target Neighborhood Hits	237	Shared Neighborhood Hits	9
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.099240 (rank : 80)
Query Neighborhood Hits	180	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.084029 (rank : 91)
Query Neighborhood Hits	180	Target Neighborhood Hits	255	Shared Neighborhood Hits	17
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

TXND2_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.054328 (rank : 131)
Query Neighborhood Hits	180	Target Neighborhood Hits	828	Shared Neighborhood Hits	84
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

Hits sorted by NC score

E41L1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	180	Target Neighborhood Hits	180	Shared Neighborhood Hits	180
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_MOUSE
NC score	0.992845 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	180	Target Neighborhood Hits	106	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L3_HUMAN
NC score	0.980953 (rank : 3)	θ value	1.72287e-176 (rank : 6)
Query Neighborhood Hits	180	Target Neighborhood Hits	113	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

41_HUMAN
NC score	0.975047 (rank : 4)	θ value	1.01709e-152 (rank : 7)
Query Neighborhood Hits	180	Target Neighborhood Hits	157	Shared Neighborhood Hits	61
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L3_MOUSE
NC score	0.973723 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	180	Target Neighborhood Hits	250	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

41_MOUSE
NC score	0.973177 (rank : 6)	θ value	1.12453e-151 (rank : 8)
Query Neighborhood Hits	180	Target Neighborhood Hits	184	Shared Neighborhood Hits	60
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L2_HUMAN
NC score	0.968879 (rank : 7)	θ value	2.74423e-182 (rank : 4)
Query Neighborhood Hits	180	Target Neighborhood Hits	287	Shared Neighborhood Hits	70
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L5_HUMAN
NC score	0.958107 (rank : 8)	θ value	7.70199e-76 (rank : 10)
Query Neighborhood Hits	180	Target Neighborhood Hits	76	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
NC score	0.956881 (rank : 9)	θ value	8.81223e-72 (rank : 11)
Query Neighborhood Hits	180	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

FRMD5_MOUSE
NC score	0.956449 (rank : 10)	θ value	1.00825e-67 (rank : 16)
Query Neighborhood Hits	180	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L2_MOUSE
NC score	0.954202 (rank : 11)	θ value	9.76035e-180 (rank : 5)
Query Neighborhood Hits	180	Target Neighborhood Hits	459	Shared Neighborhood Hits	102
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

FRMD5_HUMAN
NC score	0.954008 (rank : 12)	θ value	7.71989e-68 (rank : 15)
Query Neighborhood Hits	180	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LA_HUMAN
NC score	0.952151 (rank : 13)	θ value	4.09345e-69 (rank : 13)
Query Neighborhood Hits	180	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.951948 (rank : 14)	θ value	1.45591e-66 (rank : 17)
Query Neighborhood Hits	180	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LB_HUMAN
NC score	0.950926 (rank : 15)	θ value	1.27248e-70 (rank : 12)
Query Neighborhood Hits	180	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

MYLIP_MOUSE
NC score	0.853416 (rank : 16)	θ value	2.27234e-27 (rank : 34)
Query Neighborhood Hits	180	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.838209 (rank : 17)	θ value	1.02001e-27 (rank : 33)
Query Neighborhood Hits	180	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FARP1_HUMAN
NC score	0.793650 (rank : 18)	θ value	4.52582e-68 (rank : 14)
Query Neighborhood Hits	180	Target Neighborhood Hits	241	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FRM4B_HUMAN
NC score	0.790524 (rank : 19)	θ value	2.35151e-24 (rank : 37)
Query Neighborhood Hits	180	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.787868 (rank : 20)	θ value	3.07116e-24 (rank : 38)
Query Neighborhood Hits	180	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
NC score	0.779443 (rank : 21)	θ value	4.43474e-23 (rank : 39)
Query Neighborhood Hits	180	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
NC score	0.778024 (rank : 22)	θ value	7.56453e-23 (rank : 40)
Query Neighborhood Hits	180	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

MERL_MOUSE
NC score	0.773654 (rank : 23)	θ value	1.0531e-32 (rank : 30)
Query Neighborhood Hits	180	Target Neighborhood Hits	524	Shared Neighborhood Hits	71
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.773359 (rank : 24)	θ value	8.06329e-33 (rank : 29)
Query Neighborhood Hits	180	Target Neighborhood Hits	532	Shared Neighborhood Hits	73
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FARP2_HUMAN
NC score	0.769471 (rank : 25)	θ value	5.17823e-64 (rank : 19)
Query Neighborhood Hits	180	Target Neighborhood Hits	240	Shared Neighborhood Hits	52
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.761267 (rank : 26)	θ value	9.43692e-66 (rank : 18)
Query Neighborhood Hits	180	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

EZRI_HUMAN
NC score	0.739997 (rank : 27)	θ value	2.67802e-36 (rank : 23)
Query Neighborhood Hits	180	Target Neighborhood Hits	663	Shared Neighborhood Hits	76
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
NC score	0.735685 (rank : 28)	θ value	3.4976e-36 (rank : 24)
Query Neighborhood Hits	180	Target Neighborhood Hits	693	Shared Neighborhood Hits	79
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
NC score	0.719187 (rank : 29)	θ value	1.24399e-33 (rank : 27)
Query Neighborhood Hits	180	Target Neighborhood Hits	741	Shared Neighborhood Hits	78
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.715286 (rank : 30)	θ value	1.24399e-33 (rank : 28)
Query Neighborhood Hits	180	Target Neighborhood Hits	773	Shared Neighborhood Hits	77
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MOES_HUMAN
NC score	0.677928 (rank : 31)	θ value	1.9192e-34 (rank : 26)
Query Neighborhood Hits	180	Target Neighborhood Hits	892	Shared Neighborhood Hits	80
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTN4_HUMAN
NC score	0.673892 (rank : 32)	θ value	8.77142e-88 (rank : 9)
Query Neighborhood Hits	180	Target Neighborhood Hits	303	Shared Neighborhood Hits	53
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

MOES_MOUSE
NC score	0.670271 (rank : 33)	θ value	5.0505e-35 (rank : 25)
Query Neighborhood Hits	180	Target Neighborhood Hits	923	Shared Neighborhood Hits	78
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRMD6_MOUSE
NC score	0.662636 (rank : 34)	θ value	1.38499e-08 (rank : 45)
Query Neighborhood Hits	180	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
NC score	0.654441 (rank : 35)	θ value	3.64472e-09 (rank : 43)
Query Neighborhood Hits	180	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

PTN3_HUMAN
NC score	0.644706 (rank : 36)	θ value	1.45929e-58 (rank : 20)
Query Neighborhood Hits	180	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

FRMD1_HUMAN
NC score	0.641709 (rank : 37)	θ value	1.06045e-08 (rank : 44)
Query Neighborhood Hits	180	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

PTN21_MOUSE
NC score	0.615658 (rank : 38)	θ value	6.37413e-38 (rank : 21)
Query Neighborhood Hits	180	Target Neighborhood Hits	155	Shared Neighborhood Hits	51
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.613809 (rank : 39)	θ value	3.16345e-37 (rank : 22)
Query Neighborhood Hits	180	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
NC score	0.595867 (rank : 40)	θ value	8.91499e-32 (rank : 31)
Query Neighborhood Hits	180	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.588047 (rank : 41)	θ value	2.86786e-30 (rank : 32)
Query Neighborhood Hits	180	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_MOUSE
NC score	0.478903 (rank : 42)	θ value	8.08199e-25 (rank : 36)
Query Neighborhood Hits	180	Target Neighborhood Hits	426	Shared Neighborhood Hits	52
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.470713 (rank : 43)	θ value	1.92365e-26 (rank : 35)
Query Neighborhood Hits	180	Target Neighborhood Hits	471	Shared Neighborhood Hits	62
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

TLN1_HUMAN
NC score	0.421475 (rank : 44)	θ value	4.0297e-08 (rank : 46)
Query Neighborhood Hits	180	Target Neighborhood Hits	218	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.419273 (rank : 45)	θ value	1.63604e-09 (rank : 42)
Query Neighborhood Hits	180	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN1_MOUSE
NC score	0.418270 (rank : 46)	θ value	4.0297e-08 (rank : 47)
Query Neighborhood Hits	180	Target Neighborhood Hits	213	Shared Neighborhood Hits	45
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
NC score	0.415217 (rank : 47)	θ value	9.59137e-10 (rank : 41)
Query Neighborhood Hits	180	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

PTN2_MOUSE
NC score	0.117005 (rank : 48)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	180	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.115529 (rank : 49)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	180	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN2_HUMAN
NC score	0.115432 (rank : 50)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	180	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN18_HUMAN
NC score	0.115249 (rank : 51)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	180	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN1_HUMAN
NC score	0.115173 (rank : 52)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	180	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN18_MOUSE
NC score	0.111676 (rank : 53)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	180	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_HUMAN
NC score	0.111337 (rank : 54)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	180	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
NC score	0.110978 (rank : 55)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	180	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_HUMAN
NC score	0.108775 (rank : 56)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	180	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN7_MOUSE
NC score	0.107828 (rank : 57)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	180	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN22_MOUSE
NC score	0.107153 (rank : 58)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	180	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN7_HUMAN
NC score	0.106670 (rank : 59)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	180	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN12_MOUSE
NC score	0.106537 (rank : 60)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	180	Target Neighborhood Hits	123	Shared Neighborhood Hits	12
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN12_HUMAN
NC score	0.106537 (rank : 61)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	180	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN6_HUMAN
NC score	0.106284 (rank : 62)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	180	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
NC score	0.106257 (rank : 63)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	180	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPR2_HUMAN
NC score	0.104633 (rank : 64)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	180	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPRO_HUMAN
NC score	0.104339 (rank : 65)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	180	Target Neighborhood Hits	139	Shared Neighborhood Hits	9
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRN_HUMAN
NC score	0.104330 (rank : 66)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	180	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPR2_MOUSE
NC score	0.104073 (rank : 67)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	180	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRN_MOUSE
NC score	0.103957 (rank : 68)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	180	Target Neighborhood Hits	240	Shared Neighborhood Hits	12
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTN23_HUMAN
NC score	0.102547 (rank : 69)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	180	Target Neighborhood Hits	646	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRR_MOUSE
NC score	0.102312 (rank : 70)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	180	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRR_HUMAN
NC score	0.101977 (rank : 71)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	180	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

CD45_MOUSE
NC score	0.101701 (rank : 72)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	180	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTN23_MOUSE
NC score	0.100714 (rank : 73)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	180	Target Neighborhood Hits	726	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTPRJ_MOUSE
NC score	0.100186 (rank : 74)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	180	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN5_MOUSE
NC score	0.100112 (rank : 75)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	180	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.100112 (rank : 76)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	180	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN11_MOUSE
NC score	0.099918 (rank : 77)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	180	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.099909 (rank : 78)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	180	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTPRJ_HUMAN
NC score	0.099816 (rank : 79)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	180	Target Neighborhood Hits	207	Shared Neighborhood Hits	11
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRV_MOUSE
NC score	0.099240 (rank : 80)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	180	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRB_HUMAN
NC score	0.097762 (rank : 81)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	180	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

CD45_HUMAN
NC score	0.097008 (rank : 82)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	180	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRE_HUMAN
NC score	0.093469 (rank : 83)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	180	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.093114 (rank : 84)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	180	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
NC score	0.093077 (rank : 85)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	180	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_MOUSE
NC score	0.092982 (rank : 86)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	180	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

CA106_HUMAN
NC score	0.090186 (rank : 87)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	180	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
NC score	0.088825 (rank : 88)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	180	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

PTPRK_MOUSE
NC score	0.084409 (rank : 89)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	180	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRG_MOUSE
NC score	0.084352 (rank : 90)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	180	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRZ_HUMAN
NC score	0.084029 (rank : 91)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	180	Target Neighborhood Hits	255	Shared Neighborhood Hits	17
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

KRIT1_HUMAN
NC score	0.083823 (rank : 92)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	180	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

PTPRG_HUMAN
NC score	0.083733 (rank : 93)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	180	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRK_HUMAN
NC score	0.083694 (rank : 94)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	180	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRT_HUMAN
NC score	0.081009 (rank : 95)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	180	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.080886 (rank : 96)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	180	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRM_MOUSE
NC score	0.079068 (rank : 97)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	180	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRU_HUMAN
NC score	0.078791 (rank : 98)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	180	Target Neighborhood Hits	237	Shared Neighborhood Hits	9
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_HUMAN
NC score	0.078680 (rank : 99)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	180	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

KRIT1_MOUSE
NC score	0.077410 (rank : 100)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	180	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

NIPBL_HUMAN
NC score	0.070546 (rank : 101)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	180	Target Neighborhood Hits	1311	Shared Neighborhood Hits	106
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
NC score	0.070003 (rank : 102)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	180	Target Neighborhood Hits	1041	Shared Neighborhood Hits	89
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

IWS1_HUMAN
NC score	0.068461 (rank : 103)	θ value	0.0252991 (rank : 53)
Query Neighborhood Hits	180	Target Neighborhood Hits	1241	Shared Neighborhood Hits	104
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

HIP1_HUMAN
NC score	0.067030 (rank : 104)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	180	Target Neighborhood Hits	1016	Shared Neighborhood Hits	57
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

IWS1_MOUSE
NC score	0.066695 (rank : 105)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	180	Target Neighborhood Hits	1258	Shared Neighborhood Hits	101
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AKA12_HUMAN
NC score	0.066570 (rank : 106)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	180	Target Neighborhood Hits	825	Shared Neighborhood Hits	80
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

PTPRS_HUMAN
NC score	0.065660 (rank : 107)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	180	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

NASP_HUMAN
NC score	0.064476 (rank : 108)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	180	Target Neighborhood Hits	709	Shared Neighborhood Hits	70
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PTPRD_HUMAN
NC score	0.064458 (rank : 109)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	180	Target Neighborhood Hits	485	Shared Neighborhood Hits	12
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

ZC313_HUMAN
NC score	0.064214 (rank : 110)	θ value	0.0330416 (rank : 54)
Query Neighborhood Hits	180	Target Neighborhood Hits	772	Shared Neighborhood Hits	73
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

PTPRF_HUMAN
NC score	0.062754 (rank : 111)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	180	Target Neighborhood Hits	489	Shared Neighborhood Hits	9
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.061985 (rank : 112)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	180	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

THOC2_HUMAN
NC score	0.061660 (rank : 113)	θ value	0.00228821 (rank : 48)
Query Neighborhood Hits	180	Target Neighborhood Hits	337	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

FGD5_HUMAN
NC score	0.061395 (rank : 114)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	180	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD6_HUMAN
NC score	0.060997 (rank : 115)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	180	Target Neighborhood Hits	237	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

HIP1R_HUMAN
NC score	0.060808 (rank : 116)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	180	Target Neighborhood Hits	809	Shared Neighborhood Hits	48
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

FGD6_MOUSE
NC score	0.060738 (rank : 117)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	180	Target Neighborhood Hits	282	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

HIP1R_MOUSE
NC score	0.060590 (rank : 118)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	180	Target Neighborhood Hits	959	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

FGD4_MOUSE
NC score	0.058989 (rank : 119)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	180	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

CT2NL_HUMAN
NC score	0.058624 (rank : 120)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	180	Target Neighborhood Hits	1059	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FGD4_HUMAN
NC score	0.058568 (rank : 121)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	180	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

DMP1_HUMAN
NC score	0.057743 (rank : 122)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	180	Target Neighborhood Hits	491	Shared Neighborhood Hits	53
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

FGD5_MOUSE
NC score	0.057608 (rank : 123)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	180	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

ACINU_HUMAN
NC score	0.057451 (rank : 124)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	180	Target Neighborhood Hits	828	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

FGD1_HUMAN
NC score	0.057449 (rank : 125)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	180	Target Neighborhood Hits	367	Shared Neighborhood Hits	18
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PKHA6_MOUSE
NC score	0.055963 (rank : 126)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	180	Target Neighborhood Hits	591	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MAP1A_HUMAN
NC score	0.055801 (rank : 127)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	180	Target Neighborhood Hits	1626	Shared Neighborhood Hits	93
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

FGD1_MOUSE
NC score	0.055773 (rank : 128)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	180	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

NOP14_HUMAN
NC score	0.055092 (rank : 129)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	180	Target Neighborhood Hits	573	Shared Neighborhood Hits	63
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

CT2NL_MOUSE
NC score	0.054461 (rank : 130)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	180	Target Neighborhood Hits	902	Shared Neighborhood Hits	71
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

TXND2_MOUSE
NC score	0.054328 (rank : 131)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	180	Target Neighborhood Hits	828	Shared Neighborhood Hits	84
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

MESD1_MOUSE
NC score	0.053103 (rank : 132)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	180	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

FGD2_MOUSE
NC score	0.053063 (rank : 133)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	180	Target Neighborhood Hits	163	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

LEO1_HUMAN
NC score	0.052891 (rank : 134)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	180	Target Neighborhood Hits	958	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DNMT1_HUMAN
NC score	0.052192 (rank : 135)	θ value	0.0431538 (rank : 57)
Query Neighborhood Hits	180	Target Neighborhood Hits	401	Shared Neighborhood Hits	49
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

FGD3_HUMAN
NC score	0.051739 (rank : 136)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	180	Target Neighborhood Hits	249	Shared Neighborhood Hits	10
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

MESD1_HUMAN
NC score	0.051641 (rank : 137)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	180	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

CCD11_HUMAN
NC score	0.051286 (rank : 138)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	180	Target Neighborhood Hits	822	Shared Neighborhood Hits	51
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

ARHG4_MOUSE
NC score	0.050340 (rank : 139)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	180	Target Neighborhood Hits	185	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

TRDN_HUMAN
NC score	0.050321 (rank : 140)	θ value	0.0563607 (rank : 60)
Query Neighborhood Hits	180	Target Neighborhood Hits	542	Shared Neighborhood Hits	32
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

RBBP6_HUMAN
NC score	0.050195 (rank : 141)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	180	Target Neighborhood Hits	1135	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

NAF1_HUMAN
NC score	0.050114 (rank : 142)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	180	Target Neighborhood Hits	937	Shared Neighborhood Hits	51
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

FGD3_MOUSE
NC score	0.050052 (rank : 143)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	180	Target Neighborhood Hits	257	Shared Neighborhood Hits	8
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

TGON1_MOUSE
NC score	0.049664 (rank : 144)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	180	Target Neighborhood Hits	243	Shared Neighborhood Hits	36
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

RENT2_HUMAN
NC score	0.049068 (rank : 145)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	180	Target Neighborhood Hits	618	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

HTSF1_MOUSE
NC score	0.048044 (rank : 146)	θ value	0.0148317 (rank : 52)
Query Neighborhood Hits	180	Target Neighborhood Hits	425	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

SFR17_HUMAN
NC score	0.047376 (rank : 147)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	180	Target Neighborhood Hits	325	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

CN145_HUMAN
NC score	0.046146 (rank : 148)	θ value	0.0148317 (rank : 51)
Query Neighborhood Hits	180	Target Neighborhood Hits	1196	Shared Neighborhood Hits	60
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

NSBP1_MOUSE
NC score	0.045859 (rank : 149)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	180	Target Neighborhood Hits	681	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

K1143_MOUSE
NC score	0.043548 (rank : 150)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	180	Target Neighborhood Hits	48	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

K1143_HUMAN
NC score	0.043441 (rank : 151)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	180	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AT1, Q96HJ8, Q9ULS7	Gene names	KIAA1143
Domain Architecture	No domain graphic available
Description	Protein KIAA1143.

ITSN1_MOUSE
NC score	0.043159 (rank : 152)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	180	Target Neighborhood Hits	1669	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MDN1_HUMAN
NC score	0.042852 (rank : 153)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	180	Target Neighborhood Hits	662	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RBM6_HUMAN
NC score	0.042729 (rank : 154)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	180	Target Neighborhood Hits	221	Shared Neighborhood Hits	27
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

IF3A_HUMAN
NC score	0.042065 (rank : 155)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	180	Target Neighborhood Hits	875	Shared Neighborhood Hits	60
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

RBM25_HUMAN
NC score	0.041643 (rank : 156)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	180	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SFR12_HUMAN
NC score	0.040548 (rank : 157)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	180	Target Neighborhood Hits	553	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

IF3A_MOUSE
NC score	0.039627 (rank : 158)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	180	Target Neighborhood Hits	871	Shared Neighborhood Hits	60
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

MINT_HUMAN
NC score	0.039487 (rank : 159)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	180	Target Neighborhood Hits	1291	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MINT_MOUSE
NC score	0.038849 (rank : 160)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	180	Target Neighborhood Hits	1514	Shared Neighborhood Hits	76
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SFR12_MOUSE
NC score	0.038662 (rank : 161)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	180	Target Neighborhood Hits	486	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

CN145_MOUSE
NC score	0.038623 (rank : 162)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	180	Target Neighborhood Hits	916	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

ITSN1_HUMAN
NC score	0.038585 (rank : 163)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	180	Target Neighborhood Hits	1757	Shared Neighborhood Hits	71
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

TP53B_HUMAN
NC score	0.037908 (rank : 164)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	180	Target Neighborhood Hits	413	Shared Neighborhood Hits	38
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CCD55_HUMAN
NC score	0.037896 (rank : 165)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	180	Target Neighborhood Hits	513	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

TGON2_MOUSE
NC score	0.037583 (rank : 166)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	180	Target Neighborhood Hits	277	Shared Neighborhood Hits	41
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

MDC1_HUMAN
NC score	0.035873 (rank : 167)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	180	Target Neighborhood Hits	1446	Shared Neighborhood Hits	85
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CTR9_HUMAN
NC score	0.035326 (rank : 168)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	180	Target Neighborhood Hits	383	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

TCP10_HUMAN
NC score	0.034887 (rank : 169)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	180	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

DEK_MOUSE
NC score	0.033870 (rank : 170)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	180	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

MYST4_HUMAN
NC score	0.033391 (rank : 171)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	180	Target Neighborhood Hits	671	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TXND2_HUMAN
NC score	0.033319 (rank : 172)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	180	Target Neighborhood Hits	793	Shared Neighborhood Hits	60
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

PTMS_MOUSE
NC score	0.032873 (rank : 173)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	180	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

GIT1_MOUSE
NC score	0.032747 (rank : 174)	θ value	0.00298849 (rank : 49)
Query Neighborhood Hits	180	Target Neighborhood Hits	341	Shared Neighborhood Hits	12
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GOGA4_MOUSE
NC score	0.032725 (rank : 175)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	180	Target Neighborhood Hits	1939	Shared Neighborhood Hits	88
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

ACINU_MOUSE
NC score	0.032297 (rank : 176)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	180	Target Neighborhood Hits	712	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BEGIN_MOUSE
NC score	0.032148 (rank : 177)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	180	Target Neighborhood Hits	383	Shared Neighborhood Hits	26
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

NFM_HUMAN
NC score	0.031990 (rank : 178)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	180	Target Neighborhood Hits	1328	Shared Neighborhood Hits	72
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RPGR1_MOUSE
NC score	0.031897 (rank : 179)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	180	Target Neighborhood Hits	713	Shared Neighborhood Hits	45
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

KIF3A_MOUSE
NC score	0.031397 (rank : 180)	θ value	0.0563607 (rank : 59)
Query Neighborhood Hits	180	Target Neighborhood Hits	715	Shared Neighborhood Hits	45
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

NFM_MOUSE
NC score	0.031347 (rank : 181)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	180	Target Neighborhood Hits	1159	Shared Neighborhood Hits	70
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

LIPS_HUMAN
NC score	0.031130 (rank : 182)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	180	Target Neighborhood Hits	314	Shared Neighborhood Hits	21
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

CUTL2_HUMAN
NC score	0.030514 (rank : 183)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	180	Target Neighborhood Hits	906	Shared Neighborhood Hits	38
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

US6NL_MOUSE
NC score	0.030271 (rank : 184)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	180	Target Neighborhood Hits	157	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

IF2P_HUMAN
NC score	0.029257 (rank : 185)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	180	Target Neighborhood Hits	889	Shared Neighborhood Hits	49
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NFH_MOUSE
NC score	0.028543 (rank : 186)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	180	Target Neighborhood Hits	2247	Shared Neighborhood Hits	83
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

KIF3A_HUMAN
NC score	0.028262 (rank : 187)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	180	Target Neighborhood Hits	704	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

HTSF1_HUMAN
NC score	0.027594 (rank : 188)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	180	Target Neighborhood Hits	408	Shared Neighborhood Hits	24
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

3BP2_MOUSE
NC score	0.027557 (rank : 189)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	180	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

PPRB_HUMAN
NC score	0.027374 (rank : 190)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	180	Target Neighborhood Hits	311	Shared Neighborhood Hits	18
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

HMGN3_HUMAN
NC score	0.027255 (rank : 191)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	180	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q15651, Q7RTT0, Q969M5, Q9BZT7	Gene names	HMGN3, TRIP7
Domain Architecture	No domain graphic available
Description	High mobility group nucleosome-binding domain-containing protein 3 (Thyroid receptor-interacting protein 7) (TRIP7).

TRHY_HUMAN
NC score	0.027224 (rank : 192)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	180	Target Neighborhood Hits	1385	Shared Neighborhood Hits	62
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

AVEN_MOUSE
NC score	0.026590 (rank : 193)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	180	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D9K3	Gene names	Aven
Domain Architecture	No domain graphic available
Description	Cell death regulator Aven.

GIT1_HUMAN
NC score	0.026048 (rank : 194)	θ value	0.0736092 (rank : 61)
Query Neighborhood Hits	180	Target Neighborhood Hits	336	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

PCLO_MOUSE
NC score	0.026043 (rank : 195)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	180	Target Neighborhood Hits	2275	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NCKX1_HUMAN
NC score	0.025985 (rank : 196)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	180	Target Neighborhood Hits	223	Shared Neighborhood Hits	19
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

CTR9_MOUSE
NC score	0.025942 (rank : 197)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	180	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

BAZ2B_HUMAN
NC score	0.025737 (rank : 198)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	180	Target Neighborhood Hits	803	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

NFH_HUMAN
NC score	0.025645 (rank : 199)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	180	Target Neighborhood Hits	1242	Shared Neighborhood Hits	60
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MYO5C_HUMAN
NC score	0.025425 (rank : 200)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	180	Target Neighborhood Hits	1206	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

UBF1_MOUSE
NC score	0.024952 (rank : 201)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	180	Target Neighborhood Hits	419	Shared Neighborhood Hits	32
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

BEGIN_HUMAN
NC score	0.024708 (rank : 202)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	180	Target Neighborhood Hits	454	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

PPIG_HUMAN
NC score	0.024704 (rank : 203)	θ value	0.0736092 (rank : 63)
Query Neighborhood Hits	180	Target Neighborhood Hits	670	Shared Neighborhood Hits	65
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

WDR60_HUMAN
NC score	0.024471 (rank : 204)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	180	Target Neighborhood Hits	286	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

PCLO_HUMAN
NC score	0.023501 (rank : 205)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	180	Target Neighborhood Hits	2046	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SFRS4_MOUSE
NC score	0.023106 (rank : 206)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	180	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

AF9_HUMAN
NC score	0.022870 (rank : 207)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	180	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

NNP1_MOUSE
NC score	0.022236 (rank : 208)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	180	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

SFRS4_HUMAN
NC score	0.021734 (rank : 209)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	180	Target Neighborhood Hits	384	Shared Neighborhood Hits	30
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

ABTAP_MOUSE
NC score	0.020452 (rank : 210)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	180	Target Neighborhood Hits	381	Shared Neighborhood Hits	31
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

BRE1A_HUMAN
NC score	0.019823 (rank : 211)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	180	Target Neighborhood Hits	1071	Shared Neighborhood Hits	48
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

NUCL_MOUSE
NC score	0.019771 (rank : 212)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	180	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

MLL3_MOUSE
NC score	0.019094 (rank : 213)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	180	Target Neighborhood Hits	1399	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

BRD7_MOUSE
NC score	0.019056 (rank : 214)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	180	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

MYH10_MOUSE
NC score	0.018946 (rank : 215)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	180	Target Neighborhood Hits	1612	Shared Neighborhood Hits	66
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_HUMAN
NC score	0.018832 (rank : 216)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	180	Target Neighborhood Hits	1620	Shared Neighborhood Hits	64
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RU17_HUMAN
NC score	0.018692 (rank : 217)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	180	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

THSD1_MOUSE
NC score	0.018592 (rank : 218)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	180	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

REN3B_HUMAN
NC score	0.018181 (rank : 219)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	180	Target Neighborhood Hits	412	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

CHIC1_MOUSE
NC score	0.018138 (rank : 220)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	180	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CBW7, O08904, Q8K3S5	Gene names	Chic1, Brx
Domain Architecture	No domain graphic available
Description	Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein).

PHF14_MOUSE
NC score	0.017518 (rank : 221)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	180	Target Neighborhood Hits	342	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

MLL3_HUMAN
NC score	0.017411 (rank : 222)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	180	Target Neighborhood Hits	1644	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ANR18_HUMAN
NC score	0.016893 (rank : 223)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	180	Target Neighborhood Hits	1106	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

BRD8_MOUSE
NC score	0.016849 (rank : 224)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	180	Target Neighborhood Hits	422	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

RU17_MOUSE
NC score	0.016597 (rank : 225)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	180	Target Neighborhood Hits	278	Shared Neighborhood Hits	19
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

DDX21_HUMAN
NC score	0.016527 (rank : 226)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	180	Target Neighborhood Hits	308	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX46_MOUSE
NC score	0.016159 (rank : 227)	θ value	0.0431538 (rank : 56)
Query Neighborhood Hits	180	Target Neighborhood Hits	358	Shared Neighborhood Hits	31
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

CUTL2_MOUSE
NC score	0.016091 (rank : 228)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	180	Target Neighborhood Hits	771	Shared Neighborhood Hits	31
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

IF38_HUMAN
NC score	0.015263 (rank : 229)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	180	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

KIF3B_HUMAN
NC score	0.015214 (rank : 230)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	180	Target Neighborhood Hits	540	Shared Neighborhood Hits	24
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

KIF3B_MOUSE
NC score	0.015181 (rank : 231)	θ value	0.0961366 (rank : 65)
Query Neighborhood Hits	180	Target Neighborhood Hits	533	Shared Neighborhood Hits	24
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

MCPH1_MOUSE
NC score	0.014980 (rank : 232)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	180	Target Neighborhood Hits	116	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

DDX46_HUMAN
NC score	0.014353 (rank : 233)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	180	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

BMS1_HUMAN
NC score	0.014329 (rank : 234)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	180	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

MYT1_MOUSE
NC score	0.013720 (rank : 235)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	180	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

SETD2_HUMAN
NC score	0.012562 (rank : 236)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	180	Target Neighborhood Hits	412	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

REXO1_HUMAN
NC score	0.012504 (rank : 237)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	180	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

AP3B1_HUMAN
NC score	0.012406 (rank : 238)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	180	Target Neighborhood Hits	283	Shared Neighborhood Hits	21
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

COHA1_MOUSE
NC score	0.012062 (rank : 239)	θ value	0.0431538 (rank : 55)
Query Neighborhood Hits	180	Target Neighborhood Hits	414	Shared Neighborhood Hits	10
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MYPT1_HUMAN
NC score	0.011922 (rank : 240)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	180	Target Neighborhood Hits	723	Shared Neighborhood Hits	51
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

NOL3_MOUSE
NC score	0.011643 (rank : 241)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	180	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

BRD7_HUMAN
NC score	0.010999 (rank : 242)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	180	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

GEMI5_MOUSE
NC score	0.008320 (rank : 243)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	180	Target Neighborhood Hits	424	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

DDX51_HUMAN
NC score	0.008034 (rank : 244)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	180	Target Neighborhood Hits	332	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

TTC19_HUMAN
NC score	0.007620 (rank : 245)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	180	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q6DKK2, Q7L3U8, Q9NXB2	Gene names	TTC19
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 19 (TPR repeat protein 19).

PER3_MOUSE
NC score	0.007540 (rank : 246)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	180	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

CHD2_HUMAN
NC score	0.007267 (rank : 247)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	180	Target Neighborhood Hits	360	Shared Neighborhood Hits	24
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CD2L2_HUMAN
NC score	0.007167 (rank : 248)	θ value	0.0148317 (rank : 50)
Query Neighborhood Hits	180	Target Neighborhood Hits	1439	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CD2L1_HUMAN
NC score	0.007035 (rank : 249)	θ value	0.0563607 (rank : 58)
Query Neighborhood Hits	180	Target Neighborhood Hits	1467	Shared Neighborhood Hits	49
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD34_MOUSE
NC score	0.006689 (rank : 250)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	180	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q64314, Q62550, Q62551	Gene names	Cd34
Domain Architecture
Description	Hematopoietic progenitor cell antigen CD34 precursor.

IASPP_HUMAN
NC score	0.004802 (rank : 251)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	180	Target Neighborhood Hits	688	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CAN3_MOUSE
NC score	0.004466 (rank : 252)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	180	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

TEX14_HUMAN
NC score	0.004243 (rank : 253)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	180	Target Neighborhood Hits	1103	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

SMBT1_MOUSE
NC score	0.003750 (rank : 254)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	180	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JMD1, Q6NZD3, Q8CFS1	Gene names	Sfmbt1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1.

SLY_HUMAN
NC score	0.003446 (rank : 255)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	180	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

DNJC9_HUMAN
NC score	0.002908 (rank : 256)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	180	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXX5	Gene names	DNAJC9
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 9 (DnaJ protein SB73).

DHX36_MOUSE
NC score	0.002687 (rank : 257)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	180	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

HMGB2_MOUSE
NC score	0.002395 (rank : 258)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	180	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

NDF2_MOUSE
NC score	0.002106 (rank : 259)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	180	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

HGS_MOUSE
NC score	0.001827 (rank : 260)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	180	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

LR37B_HUMAN
NC score	0.000645 (rank : 261)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	180	Target Neighborhood Hits	392	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MK04_MOUSE
NC score	-0.003585 (rank : 262)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	180	Target Neighborhood Hits	852	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5G0	Gene names	Mapk4, Erk4, Prkm4
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4).

NEK4_MOUSE
NC score	-0.005226 (rank : 263)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	180	Target Neighborhood Hits	899	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

CTCF_MOUSE
NC score	-0.005912 (rank : 264)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	180	Target Neighborhood Hits	796	Shared Neighborhood Hits	12
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).