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Network neighborhood for query Sequence : PTN13_HUMAN

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PTN13_HUMAN
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTN13_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	471	Target Neighborhood Hits	471	Shared Neighborhood Hits	471
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	0 (rank : 2)	NC score	0.990296 (rank : 2)
Query Neighborhood Hits	471	Target Neighborhood Hits	426	Shared Neighborhood Hits	314
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN3_HUMAN
θ value	5.20228e-48 (rank : 3)	NC score	0.867212 (rank : 3)
Query Neighborhood Hits	471	Target Neighborhood Hits	258	Shared Neighborhood Hits	218
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN6_MOUSE
θ value	1.51363e-47 (rank : 4)	NC score	0.678313 (rank : 42)
Query Neighborhood Hits	471	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN4_HUMAN
θ value	4.40402e-47 (rank : 5)	NC score	0.862901 (rank : 4)
Query Neighborhood Hits	471	Target Neighborhood Hits	303	Shared Neighborhood Hits	226
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTPRF_HUMAN
θ value	4.86918e-46 (rank : 6)	NC score	0.498528 (rank : 60)
Query Neighborhood Hits	471	Target Neighborhood Hits	489	Shared Neighborhood Hits	72
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTN6_HUMAN
θ value	8.30557e-46 (rank : 7)	NC score	0.680073 (rank : 40)
Query Neighborhood Hits	471	Target Neighborhood Hits	234	Shared Neighborhood Hits	71
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTPRB_HUMAN
θ value	1.08474e-45 (rank : 8)	NC score	0.661191 (rank : 45)
Query Neighborhood Hits	471	Target Neighborhood Hits	242	Shared Neighborhood Hits	72
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRK_MOUSE
θ value	1.08474e-45 (rank : 9)	NC score	0.655975 (rank : 47)
Query Neighborhood Hits	471	Target Neighborhood Hits	223	Shared Neighborhood Hits	66
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRS_HUMAN
θ value	1.41672e-45 (rank : 10)	NC score	0.510266 (rank : 58)
Query Neighborhood Hits	471	Target Neighborhood Hits	472	Shared Neighborhood Hits	72
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTN11_HUMAN
θ value	3.15612e-45 (rank : 11)	NC score	0.662234 (rank : 44)
Query Neighborhood Hits	471	Target Neighborhood Hits	227	Shared Neighborhood Hits	71
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	3.15612e-45 (rank : 12)	NC score	0.662245 (rank : 43)
Query Neighborhood Hits	471	Target Neighborhood Hits	227	Shared Neighborhood Hits	71
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTPRD_HUMAN
θ value	9.18288e-45 (rank : 13)	NC score	0.500767 (rank : 59)
Query Neighborhood Hits	471	Target Neighborhood Hits	485	Shared Neighborhood Hits	74
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRK_HUMAN
θ value	1.19932e-44 (rank : 14)	NC score	0.657277 (rank : 46)
Query Neighborhood Hits	471	Target Neighborhood Hits	228	Shared Neighborhood Hits	66
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRJ_HUMAN
θ value	2.67181e-44 (rank : 15)	NC score	0.685320 (rank : 39)
Query Neighborhood Hits	471	Target Neighborhood Hits	207	Shared Neighborhood Hits	76
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRT_HUMAN
θ value	4.55743e-44 (rank : 16)	NC score	0.652542 (rank : 48)
Query Neighborhood Hits	471	Target Neighborhood Hits	217	Shared Neighborhood Hits	67
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	4.55743e-44 (rank : 17)	NC score	0.652528 (rank : 49)
Query Neighborhood Hits	471	Target Neighborhood Hits	219	Shared Neighborhood Hits	66
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRJ_MOUSE
θ value	1.01529e-43 (rank : 18)	NC score	0.688321 (rank : 38)
Query Neighborhood Hits	471	Target Neighborhood Hits	188	Shared Neighborhood Hits	70
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN21_MOUSE
θ value	2.26182e-43 (rank : 19)	NC score	0.804840 (rank : 5)
Query Neighborhood Hits	471	Target Neighborhood Hits	155	Shared Neighborhood Hits	105
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN2_MOUSE
θ value	3.85808e-43 (rank : 20)	NC score	0.722059 (rank : 9)
Query Neighborhood Hits	471	Target Neighborhood Hits	107	Shared Neighborhood Hits	68
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN21_HUMAN
θ value	5.03882e-43 (rank : 21)	NC score	0.804710 (rank : 6)
Query Neighborhood Hits	471	Target Neighborhood Hits	143	Shared Neighborhood Hits	104
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN1_MOUSE
θ value	6.58091e-43 (rank : 22)	NC score	0.722019 (rank : 10)
Query Neighborhood Hits	471	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN1_HUMAN
θ value	8.59492e-43 (rank : 23)	NC score	0.721525 (rank : 12)
Query Neighborhood Hits	471	Target Neighborhood Hits	84	Shared Neighborhood Hits	65
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN14_HUMAN
θ value	1.91475e-42 (rank : 24)	NC score	0.804429 (rank : 7)
Query Neighborhood Hits	471	Target Neighborhood Hits	163	Shared Neighborhood Hits	112
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTPRD_MOUSE
θ value	2.50074e-42 (rank : 25)	NC score	0.492290 (rank : 62)
Query Neighborhood Hits	471	Target Neighborhood Hits	491	Shared Neighborhood Hits	74
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTN2_HUMAN
θ value	4.2656e-42 (rank : 26)	NC score	0.721542 (rank : 11)
Query Neighborhood Hits	471	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN14_MOUSE
θ value	1.62093e-41 (rank : 27)	NC score	0.804274 (rank : 8)
Query Neighborhood Hits	471	Target Neighborhood Hits	142	Shared Neighborhood Hits	107
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN12_HUMAN
θ value	2.11701e-41 (rank : 28)	NC score	0.714310 (rank : 17)
Query Neighborhood Hits	471	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTPRM_HUMAN
θ value	2.76489e-41 (rank : 29)	NC score	0.640329 (rank : 52)
Query Neighborhood Hits	471	Target Neighborhood Hits	244	Shared Neighborhood Hits	66
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRE_HUMAN
θ value	4.71619e-41 (rank : 30)	NC score	0.702452 (rank : 31)
Query Neighborhood Hits	471	Target Neighborhood Hits	92	Shared Neighborhood Hits	69
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRM_MOUSE
θ value	4.71619e-41 (rank : 31)	NC score	0.641749 (rank : 51)
Query Neighborhood Hits	471	Target Neighborhood Hits	238	Shared Neighborhood Hits	66
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRE_MOUSE
θ value	6.15952e-41 (rank : 32)	NC score	0.702392 (rank : 32)
Query Neighborhood Hits	471	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTN12_MOUSE
θ value	8.04462e-41 (rank : 33)	NC score	0.713658 (rank : 18)
Query Neighborhood Hits	471	Target Neighborhood Hits	123	Shared Neighborhood Hits	72
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRA_HUMAN
θ value	1.05066e-40 (rank : 34)	NC score	0.701551 (rank : 33)
Query Neighborhood Hits	471	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

CD45_HUMAN
θ value	1.79215e-40 (rank : 35)	NC score	0.698985 (rank : 36)
Query Neighborhood Hits	471	Target Neighborhood Hits	243	Shared Neighborhood Hits	78
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	5.21438e-40 (rank : 36)	NC score	0.703424 (rank : 29)
Query Neighborhood Hits	471	Target Neighborhood Hits	178	Shared Neighborhood Hits	70
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRO_HUMAN
θ value	8.89434e-40 (rank : 37)	NC score	0.708365 (rank : 23)
Query Neighborhood Hits	471	Target Neighborhood Hits	139	Shared Neighborhood Hits	71
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTN18_HUMAN
θ value	1.98146e-39 (rank : 38)	NC score	0.720911 (rank : 13)
Query Neighborhood Hits	471	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN7_HUMAN
θ value	4.41421e-39 (rank : 39)	NC score	0.718381 (rank : 15)
Query Neighborhood Hits	471	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	4.41421e-39 (rank : 40)	NC score	0.718987 (rank : 14)
Query Neighborhood Hits	471	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN22_MOUSE
θ value	9.83387e-39 (rank : 41)	NC score	0.708701 (rank : 20)
Query Neighborhood Hits	471	Target Neighborhood Hits	179	Shared Neighborhood Hits	74
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN22_HUMAN
θ value	2.19075e-38 (rank : 42)	NC score	0.712912 (rank : 19)
Query Neighborhood Hits	471	Target Neighborhood Hits	109	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTPRV_MOUSE
θ value	2.19075e-38 (rank : 43)	NC score	0.678881 (rank : 41)
Query Neighborhood Hits	471	Target Neighborhood Hits	179	Shared Neighborhood Hits	68
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN18_MOUSE
θ value	7.04741e-37 (rank : 44)	NC score	0.718136 (rank : 16)
Query Neighborhood Hits	471	Target Neighborhood Hits	134	Shared Neighborhood Hits	73
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_HUMAN
θ value	1.20211e-36 (rank : 45)	NC score	0.703440 (rank : 28)
Query Neighborhood Hits	471	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	2.05049e-36 (rank : 46)	NC score	0.703586 (rank : 27)
Query Neighborhood Hits	471	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPRN_MOUSE
θ value	2.67802e-36 (rank : 47)	NC score	0.697777 (rank : 37)
Query Neighborhood Hits	471	Target Neighborhood Hits	240	Shared Neighborhood Hits	73
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRN_HUMAN
θ value	5.96599e-36 (rank : 48)	NC score	0.700521 (rank : 34)
Query Neighborhood Hits	471	Target Neighborhood Hits	156	Shared Neighborhood Hits	68
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRR_HUMAN
θ value	5.96599e-36 (rank : 49)	NC score	0.708023 (rank : 24)
Query Neighborhood Hits	471	Target Neighborhood Hits	77	Shared Neighborhood Hits	70
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRA_MOUSE
θ value	7.79185e-36 (rank : 50)	NC score	0.699460 (rank : 35)
Query Neighborhood Hits	471	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

MPDZ_MOUSE
θ value	2.26708e-35 (rank : 51)	NC score	0.491549 (rank : 63)
Query Neighborhood Hits	471	Target Neighborhood Hits	298	Shared Neighborhood Hits	197
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PTPRG_HUMAN
θ value	5.0505e-35 (rank : 52)	NC score	0.630531 (rank : 54)
Query Neighborhood Hits	471	Target Neighborhood Hits	231	Shared Neighborhood Hits	70
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPR2_MOUSE
θ value	6.59618e-35 (rank : 53)	NC score	0.703133 (rank : 30)
Query Neighborhood Hits	471	Target Neighborhood Hits	120	Shared Neighborhood Hits	69
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPR2_HUMAN
θ value	1.12514e-34 (rank : 54)	NC score	0.704276 (rank : 26)
Query Neighborhood Hits	471	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPRR_MOUSE
θ value	1.46948e-34 (rank : 55)	NC score	0.706412 (rank : 25)
Query Neighborhood Hits	471	Target Neighborhood Hits	84	Shared Neighborhood Hits	68
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRZ_HUMAN
θ value	3.27365e-34 (rank : 56)	NC score	0.634055 (rank : 53)
Query Neighborhood Hits	471	Target Neighborhood Hits	255	Shared Neighborhood Hits	85
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_MOUSE
θ value	7.29293e-34 (rank : 57)	NC score	0.628537 (rank : 55)
Query Neighborhood Hits	471	Target Neighborhood Hits	260	Shared Neighborhood Hits	75
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

MERL_HUMAN
θ value	2.12192e-33 (rank : 58)	NC score	0.449567 (rank : 94)
Query Neighborhood Hits	471	Target Neighborhood Hits	532	Shared Neighborhood Hits	84
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	2.12192e-33 (rank : 59)	NC score	0.449176 (rank : 95)
Query Neighborhood Hits	471	Target Neighborhood Hits	524	Shared Neighborhood Hits	83
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PTPRU_HUMAN
θ value	3.61944e-33 (rank : 60)	NC score	0.643874 (rank : 50)
Query Neighborhood Hits	471	Target Neighborhood Hits	237	Shared Neighborhood Hits	69
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

MPDZ_HUMAN
θ value	8.06329e-33 (rank : 61)	NC score	0.489947 (rank : 64)
Query Neighborhood Hits	471	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

FRMD6_MOUSE
θ value	8.91499e-32 (rank : 62)	NC score	0.472460 (rank : 73)
Query Neighborhood Hits	471	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

RADI_HUMAN
θ value	1.52067e-31 (rank : 63)	NC score	0.415212 (rank : 128)
Query Neighborhood Hits	471	Target Neighborhood Hits	741	Shared Neighborhood Hits	86
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	1.52067e-31 (rank : 64)	NC score	0.412957 (rank : 131)
Query Neighborhood Hits	471	Target Neighborhood Hits	773	Shared Neighborhood Hits	87
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

PTN5_MOUSE
θ value	2.59387e-31 (rank : 65)	NC score	0.708541 (rank : 21)
Query Neighborhood Hits	471	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN23_HUMAN
θ value	3.3877e-31 (rank : 66)	NC score	0.619227 (rank : 57)
Query Neighborhood Hits	471	Target Neighborhood Hits	646	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN5_HUMAN
θ value	7.54701e-31 (rank : 67)	NC score	0.708533 (rank : 22)
Query Neighborhood Hits	471	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

FRMD6_HUMAN
θ value	4.89182e-30 (rank : 68)	NC score	0.467709 (rank : 81)
Query Neighborhood Hits	471	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

PTN23_MOUSE
θ value	8.3442e-30 (rank : 69)	NC score	0.620752 (rank : 56)
Query Neighborhood Hits	471	Target Neighborhood Hits	726	Shared Neighborhood Hits	92
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MOES_MOUSE
θ value	1.85889e-29 (rank : 70)	NC score	0.385172 (rank : 143)
Query Neighborhood Hits	471	Target Neighborhood Hits	923	Shared Neighborhood Hits	90
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
θ value	2.42779e-29 (rank : 71)	NC score	0.389255 (rank : 139)
Query Neighborhood Hits	471	Target Neighborhood Hits	892	Shared Neighborhood Hits	85
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRMD1_HUMAN
θ value	4.14116e-29 (rank : 72)	NC score	0.469793 (rank : 78)
Query Neighborhood Hits	471	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

EZRI_HUMAN
θ value	2.05525e-28 (rank : 73)	NC score	0.422357 (rank : 116)
Query Neighborhood Hits	471	Target Neighborhood Hits	663	Shared Neighborhood Hits	87
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	2.68423e-28 (rank : 74)	NC score	0.421195 (rank : 119)
Query Neighborhood Hits	471	Target Neighborhood Hits	693	Shared Neighborhood Hits	86
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

E41LA_HUMAN
θ value	2.27234e-27 (rank : 75)	NC score	0.489529 (rank : 65)
Query Neighborhood Hits	471	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
θ value	8.63488e-27 (rank : 76)	NC score	0.488978 (rank : 66)
Query Neighborhood Hits	471	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41L1_HUMAN
θ value	1.92365e-26 (rank : 77)	NC score	0.470713 (rank : 77)
Query Neighborhood Hits	471	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

INADL_MOUSE
θ value	1.92365e-26 (rank : 78)	NC score	0.484210 (rank : 67)
Query Neighborhood Hits	471	Target Neighborhood Hits	290	Shared Neighborhood Hits	200
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

41_HUMAN
θ value	4.28545e-26 (rank : 79)	NC score	0.472047 (rank : 75)
Query Neighborhood Hits	471	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L1_MOUSE
θ value	4.28545e-26 (rank : 80)	NC score	0.472332 (rank : 74)
Query Neighborhood Hits	471	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L2_HUMAN
θ value	4.28545e-26 (rank : 81)	NC score	0.465765 (rank : 82)
Query Neighborhood Hits	471	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L3_HUMAN
θ value	2.12685e-25 (rank : 82)	NC score	0.472655 (rank : 72)
Query Neighborhood Hits	471	Target Neighborhood Hits	113	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L3_MOUSE
θ value	8.08199e-25 (rank : 83)	NC score	0.465209 (rank : 83)
Query Neighborhood Hits	471	Target Neighborhood Hits	250	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_MOUSE
θ value	1.05554e-24 (rank : 84)	NC score	0.451819 (rank : 93)
Query Neighborhood Hits	471	Target Neighborhood Hits	459	Shared Neighborhood Hits	84
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

41_MOUSE
θ value	8.93572e-24 (rank : 85)	NC score	0.468829 (rank : 79)
Query Neighborhood Hits	471	Target Neighborhood Hits	184	Shared Neighborhood Hits	62
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

DLG2_MOUSE
θ value	7.56453e-23 (rank : 86)	NC score	0.432488 (rank : 105)
Query Neighborhood Hits	471	Target Neighborhood Hits	271	Shared Neighborhood Hits	179
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_HUMAN
θ value	3.17815e-21 (rank : 87)	NC score	0.431167 (rank : 107)
Query Neighborhood Hits	471	Target Neighborhood Hits	279	Shared Neighborhood Hits	180
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PDZD2_HUMAN
θ value	5.42112e-21 (rank : 88)	NC score	0.441449 (rank : 99)
Query Neighborhood Hits	471	Target Neighborhood Hits	772	Shared Neighborhood Hits	214
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

E41LB_MOUSE
θ value	9.24701e-21 (rank : 89)	NC score	0.474093 (rank : 69)
Query Neighborhood Hits	471	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

DLG1_HUMAN
θ value	1.2077e-20 (rank : 90)	NC score	0.427539 (rank : 111)
Query Neighborhood Hits	471	Target Neighborhood Hits	290	Shared Neighborhood Hits	182
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	3.51386e-20 (rank : 91)	NC score	0.425910 (rank : 114)
Query Neighborhood Hits	471	Target Neighborhood Hits	285	Shared Neighborhood Hits	173
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

FARP2_MOUSE
θ value	3.51386e-20 (rank : 92)	NC score	0.374707 (rank : 152)
Query Neighborhood Hits	471	Target Neighborhood Hits	209	Shared Neighborhood Hits	56
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MAGI2_MOUSE
θ value	3.51386e-20 (rank : 93)	NC score	0.412979 (rank : 130)
Query Neighborhood Hits	471	Target Neighborhood Hits	370	Shared Neighborhood Hits	195
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

INADL_HUMAN
θ value	4.58923e-20 (rank : 94)	NC score	0.481544 (rank : 68)
Query Neighborhood Hits	471	Target Neighborhood Hits	260	Shared Neighborhood Hits	196
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

MAGI1_HUMAN
θ value	4.58923e-20 (rank : 95)	NC score	0.419595 (rank : 125)
Query Neighborhood Hits	471	Target Neighborhood Hits	388	Shared Neighborhood Hits	211
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

E41L5_HUMAN
θ value	5.99374e-20 (rank : 96)	NC score	0.473544 (rank : 70)
Query Neighborhood Hits	471	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

DLG3_HUMAN
θ value	1.33526e-19 (rank : 97)	NC score	0.426606 (rank : 113)
Query Neighborhood Hits	471	Target Neighborhood Hits	269	Shared Neighborhood Hits	181
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	1.33526e-19 (rank : 98)	NC score	0.428286 (rank : 109)
Query Neighborhood Hits	471	Target Neighborhood Hits	274	Shared Neighborhood Hits	181
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG4_MOUSE
θ value	1.74391e-19 (rank : 99)	NC score	0.434932 (rank : 102)
Query Neighborhood Hits	471	Target Neighborhood Hits	282	Shared Neighborhood Hits	183
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
θ value	2.27762e-19 (rank : 100)	NC score	0.434222 (rank : 103)
Query Neighborhood Hits	471	Target Neighborhood Hits	286	Shared Neighborhood Hits	181
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

LAP4_MOUSE
θ value	2.27762e-19 (rank : 101)	NC score	0.300887 (rank : 180)
Query Neighborhood Hits	471	Target Neighborhood Hits	590	Shared Neighborhood Hits	201
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MAGI2_HUMAN
θ value	2.97466e-19 (rank : 102)	NC score	0.410734 (rank : 132)
Query Neighborhood Hits	471	Target Neighborhood Hits	373	Shared Neighborhood Hits	190
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

E41LB_HUMAN
θ value	5.07402e-19 (rank : 103)	NC score	0.468190 (rank : 80)
Query Neighborhood Hits	471	Target Neighborhood Hits	79	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

FRM4A_MOUSE
θ value	6.62687e-19 (rank : 104)	NC score	0.441027 (rank : 100)
Query Neighborhood Hits	471	Target Neighborhood Hits	108	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

PARD3_HUMAN
θ value	8.65492e-19 (rank : 105)	NC score	0.457412 (rank : 85)
Query Neighborhood Hits	471	Target Neighborhood Hits	312	Shared Neighborhood Hits	186
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
θ value	8.65492e-19 (rank : 106)	NC score	0.456150 (rank : 89)
Query Neighborhood Hits	471	Target Neighborhood Hits	290	Shared Neighborhood Hits	185
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

FRM4A_HUMAN
θ value	1.13037e-18 (rank : 107)	NC score	0.441566 (rank : 98)
Query Neighborhood Hits	471	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

LAP4_HUMAN
θ value	1.13037e-18 (rank : 108)	NC score	0.301024 (rank : 178)
Query Neighborhood Hits	471	Target Neighborhood Hits	608	Shared Neighborhood Hits	197
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LNX2_HUMAN
θ value	1.13037e-18 (rank : 109)	NC score	0.422360 (rank : 115)
Query Neighborhood Hits	471	Target Neighborhood Hits	389	Shared Neighborhood Hits	177
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MAGI1_MOUSE
θ value	7.32683e-18 (rank : 110)	NC score	0.421729 (rank : 118)
Query Neighborhood Hits	471	Target Neighborhood Hits	403	Shared Neighborhood Hits	213
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

FRM4B_MOUSE
θ value	9.56915e-18 (rank : 111)	NC score	0.443676 (rank : 97)
Query Neighborhood Hits	471	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FARP2_HUMAN
θ value	2.13179e-17 (rank : 112)	NC score	0.376143 (rank : 151)
Query Neighborhood Hits	471	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FRM4B_HUMAN
θ value	2.13179e-17 (rank : 113)	NC score	0.444170 (rank : 96)
Query Neighborhood Hits	471	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRMD5_MOUSE
θ value	2.35696e-16 (rank : 114)	NC score	0.473298 (rank : 71)
Query Neighborhood Hits	471	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FARP1_HUMAN
θ value	5.25075e-16 (rank : 115)	NC score	0.387294 (rank : 140)
Query Neighborhood Hits	471	Target Neighborhood Hits	241	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

LNX2_MOUSE
θ value	5.25075e-16 (rank : 116)	NC score	0.428112 (rank : 110)
Query Neighborhood Hits	471	Target Neighborhood Hits	407	Shared Neighborhood Hits	179
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PAR3L_HUMAN
θ value	6.85773e-16 (rank : 117)	NC score	0.460682 (rank : 84)
Query Neighborhood Hits	471	Target Neighborhood Hits	297	Shared Neighborhood Hits	165
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

FRMD5_HUMAN
θ value	2.60593e-15 (rank : 118)	NC score	0.471713 (rank : 76)
Query Neighborhood Hits	471	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

ZO2_MOUSE
θ value	1.09485e-13 (rank : 119)	NC score	0.362794 (rank : 156)
Query Neighborhood Hits	471	Target Neighborhood Hits	296	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

LNX1_HUMAN
θ value	1.42992e-13 (rank : 120)	NC score	0.407903 (rank : 133)
Query Neighborhood Hits	471	Target Neighborhood Hits	379	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

ZO2_HUMAN
θ value	1.86753e-13 (rank : 121)	NC score	0.363964 (rank : 155)
Query Neighborhood Hits	471	Target Neighborhood Hits	289	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

LNX1_MOUSE
θ value	2.43908e-13 (rank : 122)	NC score	0.414150 (rank : 129)
Query Neighborhood Hits	471	Target Neighborhood Hits	377	Shared Neighborhood Hits	179
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

IL16_HUMAN
θ value	4.16044e-13 (rank : 123)	NC score	0.433146 (rank : 104)
Query Neighborhood Hits	471	Target Neighborhood Hits	207	Shared Neighborhood Hits	148
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IL16_MOUSE
θ value	4.16044e-13 (rank : 124)	NC score	0.420379 (rank : 121)
Query Neighborhood Hits	471	Target Neighborhood Hits	189	Shared Neighborhood Hits	139
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

K1849_MOUSE
θ value	7.09661e-13 (rank : 125)	NC score	0.345991 (rank : 166)
Query Neighborhood Hits	471	Target Neighborhood Hits	335	Shared Neighborhood Hits	153
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_HUMAN
θ value	2.69671e-12 (rank : 126)	NC score	0.354876 (rank : 161)
Query Neighborhood Hits	471	Target Neighborhood Hits	220	Shared Neighborhood Hits	141
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

GRIP2_HUMAN
θ value	3.52202e-12 (rank : 127)	NC score	0.426768 (rank : 112)
Query Neighborhood Hits	471	Target Neighborhood Hits	256	Shared Neighborhood Hits	191
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

NHERF_MOUSE
θ value	6.00763e-12 (rank : 128)	NC score	0.397595 (rank : 137)
Query Neighborhood Hits	471	Target Neighborhood Hits	195	Shared Neighborhood Hits	158
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

ZO1_MOUSE
θ value	1.02475e-11 (rank : 129)	NC score	0.364484 (rank : 154)
Query Neighborhood Hits	471	Target Neighborhood Hits	453	Shared Neighborhood Hits	178
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

LIN7B_HUMAN
θ value	1.33837e-11 (rank : 130)	NC score	0.456951 (rank : 86)
Query Neighborhood Hits	471	Target Neighborhood Hits	200	Shared Neighborhood Hits	181
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

PDZD1_MOUSE
θ value	1.74796e-11 (rank : 131)	NC score	0.405021 (rank : 135)
Query Neighborhood Hits	471	Target Neighborhood Hits	191	Shared Neighborhood Hits	155
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ZO1_HUMAN
θ value	2.28291e-11 (rank : 132)	NC score	0.361478 (rank : 157)
Query Neighborhood Hits	471	Target Neighborhood Hits	474	Shared Neighborhood Hits	178
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

LIN7B_MOUSE
θ value	2.98157e-11 (rank : 133)	NC score	0.455954 (rank : 90)
Query Neighborhood Hits	471	Target Neighborhood Hits	200	Shared Neighborhood Hits	181
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

NEB1_HUMAN
θ value	2.98157e-11 (rank : 134)	NC score	0.303687 (rank : 176)
Query Neighborhood Hits	471	Target Neighborhood Hits	829	Shared Neighborhood Hits	182
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

LIN7C_HUMAN
θ value	3.89403e-11 (rank : 135)	NC score	0.456764 (rank : 87)
Query Neighborhood Hits	471	Target Neighborhood Hits	198	Shared Neighborhood Hits	181
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	3.89403e-11 (rank : 136)	NC score	0.456764 (rank : 88)
Query Neighborhood Hits	471	Target Neighborhood Hits	198	Shared Neighborhood Hits	181
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7A_HUMAN
θ value	5.08577e-11 (rank : 137)	NC score	0.452310 (rank : 91)
Query Neighborhood Hits	471	Target Neighborhood Hits	193	Shared Neighborhood Hits	178
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	5.08577e-11 (rank : 138)	NC score	0.452288 (rank : 92)
Query Neighborhood Hits	471	Target Neighborhood Hits	193	Shared Neighborhood Hits	178
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

NEB2_HUMAN
θ value	1.47974e-10 (rank : 139)	NC score	0.287975 (rank : 184)
Query Neighborhood Hits	471	Target Neighborhood Hits	883	Shared Neighborhood Hits	155
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	1.47974e-10 (rank : 140)	NC score	0.283304 (rank : 185)
Query Neighborhood Hits	471	Target Neighborhood Hits	889	Shared Neighborhood Hits	159
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SYJ2B_HUMAN
θ value	2.52405e-10 (rank : 141)	NC score	0.492479 (rank : 61)
Query Neighborhood Hits	471	Target Neighborhood Hits	162	Shared Neighborhood Hits	154
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

NHERF_HUMAN
θ value	4.30538e-10 (rank : 142)	NC score	0.383679 (rank : 144)
Query Neighborhood Hits	471	Target Neighborhood Hits	190	Shared Neighborhood Hits	156
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

GRIP1_HUMAN
θ value	7.34386e-10 (rank : 143)	NC score	0.417482 (rank : 127)
Query Neighborhood Hits	471	Target Neighborhood Hits	231	Shared Neighborhood Hits	192
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

ZO3_MOUSE
θ value	7.34386e-10 (rank : 144)	NC score	0.383382 (rank : 145)
Query Neighborhood Hits	471	Target Neighborhood Hits	224	Shared Neighborhood Hits	175
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

GRIP1_MOUSE
θ value	9.59137e-10 (rank : 145)	NC score	0.417546 (rank : 126)
Query Neighborhood Hits	471	Target Neighborhood Hits	241	Shared Neighborhood Hits	191
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

NHRF2_HUMAN
θ value	1.25267e-09 (rank : 146)	NC score	0.386917 (rank : 141)
Query Neighborhood Hits	471	Target Neighborhood Hits	197	Shared Neighborhood Hits	165
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PDZD1_HUMAN
θ value	2.13673e-09 (rank : 147)	NC score	0.398380 (rank : 136)
Query Neighborhood Hits	471	Target Neighborhood Hits	190	Shared Neighborhood Hits	155
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

DVL2_HUMAN
θ value	2.79066e-09 (rank : 148)	NC score	0.293743 (rank : 181)
Query Neighborhood Hits	471	Target Neighborhood Hits	223	Shared Neighborhood Hits	120
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

WHRN_MOUSE
θ value	2.79066e-09 (rank : 149)	NC score	0.422000 (rank : 117)
Query Neighborhood Hits	471	Target Neighborhood Hits	412	Shared Neighborhood Hits	193
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

AFAD_HUMAN
θ value	3.64472e-09 (rank : 150)	NC score	0.312297 (rank : 173)
Query Neighborhood Hits	471	Target Neighborhood Hits	689	Shared Neighborhood Hits	162
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PDZD3_HUMAN
θ value	4.76016e-09 (rank : 151)	NC score	0.370289 (rank : 153)
Query Neighborhood Hits	471	Target Neighborhood Hits	180	Shared Neighborhood Hits	157
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

MYLIP_MOUSE
θ value	8.11959e-09 (rank : 152)	NC score	0.430246 (rank : 108)
Query Neighborhood Hits	471	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

DVL2_MOUSE
θ value	1.06045e-08 (rank : 153)	NC score	0.293078 (rank : 182)
Query Neighborhood Hits	471	Target Neighborhood Hits	233	Shared Neighborhood Hits	119
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

WHRN_HUMAN
θ value	1.06045e-08 (rank : 154)	NC score	0.420058 (rank : 123)
Query Neighborhood Hits	471	Target Neighborhood Hits	325	Shared Neighborhood Hits	190
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

NOS1_MOUSE
θ value	1.38499e-08 (rank : 155)	NC score	0.192972 (rank : 236)
Query Neighborhood Hits	471	Target Neighborhood Hits	155	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PZRN3_HUMAN
θ value	1.80886e-08 (rank : 156)	NC score	0.340049 (rank : 169)
Query Neighborhood Hits	471	Target Neighborhood Hits	461	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	1.80886e-08 (rank : 157)	NC score	0.347937 (rank : 164)
Query Neighborhood Hits	471	Target Neighborhood Hits	438	Shared Neighborhood Hits	152
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

DVL1_MOUSE
θ value	2.36244e-08 (rank : 158)	NC score	0.300995 (rank : 179)
Query Neighborhood Hits	471	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

MYLIP_HUMAN
θ value	2.36244e-08 (rank : 159)	NC score	0.420818 (rank : 120)
Query Neighborhood Hits	471	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NOS1_HUMAN
θ value	2.36244e-08 (rank : 160)	NC score	0.215924 (rank : 224)
Query Neighborhood Hits	471	Target Neighborhood Hits	218	Shared Neighborhood Hits	137
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

TLN1_MOUSE
θ value	2.36244e-08 (rank : 161)	NC score	0.240640 (rank : 208)
Query Neighborhood Hits	471	Target Neighborhood Hits	213	Shared Neighborhood Hits	57
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

DVL3_HUMAN
θ value	3.08544e-08 (rank : 162)	NC score	0.305272 (rank : 174)
Query Neighborhood Hits	471	Target Neighborhood Hits	194	Shared Neighborhood Hits	118
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

NHRF2_MOUSE
θ value	3.08544e-08 (rank : 163)	NC score	0.376939 (rank : 150)
Query Neighborhood Hits	471	Target Neighborhood Hits	194	Shared Neighborhood Hits	165
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

USH1C_HUMAN
θ value	3.08544e-08 (rank : 164)	NC score	0.431996 (rank : 106)
Query Neighborhood Hits	471	Target Neighborhood Hits	327	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	3.08544e-08 (rank : 165)	NC score	0.405147 (rank : 134)
Query Neighborhood Hits	471	Target Neighborhood Hits	557	Shared Neighborhood Hits	208
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

TLN1_HUMAN
θ value	4.0297e-08 (rank : 166)	NC score	0.242026 (rank : 206)
Query Neighborhood Hits	471	Target Neighborhood Hits	218	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

ZO3_HUMAN
θ value	4.0297e-08 (rank : 167)	NC score	0.378613 (rank : 148)
Query Neighborhood Hits	471	Target Neighborhood Hits	219	Shared Neighborhood Hits	170
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PDZD7_HUMAN
θ value	6.87365e-08 (rank : 168)	NC score	0.436383 (rank : 101)
Query Neighborhood Hits	471	Target Neighborhood Hits	181	Shared Neighborhood Hits	166
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PZRN3_MOUSE
θ value	8.97725e-08 (rank : 169)	NC score	0.339567 (rank : 170)
Query Neighborhood Hits	471	Target Neighborhood Hits	447	Shared Neighborhood Hits	155
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

DVL3_MOUSE
θ value	1.17247e-07 (rank : 170)	NC score	0.304628 (rank : 175)
Query Neighborhood Hits	471	Target Neighborhood Hits	198	Shared Neighborhood Hits	118
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

RIMS2_HUMAN
θ value	1.99992e-07 (rank : 171)	NC score	0.156254 (rank : 249)
Query Neighborhood Hits	471	Target Neighborhood Hits	342	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	2.61198e-07 (rank : 172)	NC score	0.156842 (rank : 248)
Query Neighborhood Hits	471	Target Neighborhood Hits	376	Shared Neighborhood Hits	127
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

DVL1_HUMAN
θ value	3.41135e-07 (rank : 173)	NC score	0.302124 (rank : 177)
Query Neighborhood Hits	471	Target Neighborhood Hits	158	Shared Neighborhood Hits	119
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

GOPC_HUMAN
θ value	4.45536e-07 (rank : 174)	NC score	0.386268 (rank : 142)
Query Neighborhood Hits	471	Target Neighborhood Hits	377	Shared Neighborhood Hits	176
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	4.45536e-07 (rank : 175)	NC score	0.391681 (rank : 138)
Query Neighborhood Hits	471	Target Neighborhood Hits	323	Shared Neighborhood Hits	174
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PDZ11_MOUSE
θ value	4.45536e-07 (rank : 176)	NC score	0.420329 (rank : 122)
Query Neighborhood Hits	471	Target Neighborhood Hits	154	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SNTG2_HUMAN
θ value	4.45536e-07 (rank : 177)	NC score	0.377306 (rank : 149)
Query Neighborhood Hits	471	Target Neighborhood Hits	191	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG2_MOUSE
θ value	4.45536e-07 (rank : 178)	NC score	0.360332 (rank : 158)
Query Neighborhood Hits	471	Target Neighborhood Hits	176	Shared Neighborhood Hits	165
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

STXB4_HUMAN
θ value	4.45536e-07 (rank : 179)	NC score	0.272466 (rank : 188)
Query Neighborhood Hits	471	Target Neighborhood Hits	616	Shared Neighborhood Hits	134
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DLG5_HUMAN
θ value	5.81887e-07 (rank : 180)	NC score	0.268205 (rank : 190)
Query Neighborhood Hits	471	Target Neighborhood Hits	1088	Shared Neighborhood Hits	206
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DVL1L_HUMAN
θ value	5.81887e-07 (rank : 181)	NC score	0.292435 (rank : 183)
Query Neighborhood Hits	471	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

SNTG1_MOUSE
θ value	7.59969e-07 (rank : 182)	NC score	0.351441 (rank : 162)
Query Neighborhood Hits	471	Target Neighborhood Hits	179	Shared Neighborhood Hits	169
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PDZ11_HUMAN
θ value	9.92553e-07 (rank : 183)	NC score	0.419687 (rank : 124)
Query Neighborhood Hits	471	Target Neighborhood Hits	160	Shared Neighborhood Hits	146
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

TLN2_HUMAN
θ value	9.92553e-07 (rank : 184)	NC score	0.237869 (rank : 212)
Query Neighborhood Hits	471	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

STXB4_MOUSE
θ value	1.29631e-06 (rank : 185)	NC score	0.262220 (rank : 193)
Query Neighborhood Hits	471	Target Neighborhood Hits	629	Shared Neighborhood Hits	121
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TLN2_MOUSE
θ value	1.69304e-06 (rank : 186)	NC score	0.241347 (rank : 207)
Query Neighborhood Hits	471	Target Neighborhood Hits	149	Shared Neighborhood Hits	55
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

ARHGC_MOUSE
θ value	2.21117e-06 (rank : 187)	NC score	0.196827 (rank : 232)
Query Neighborhood Hits	471	Target Neighborhood Hits	344	Shared Neighborhood Hits	149
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_HUMAN
θ value	2.88788e-06 (rank : 188)	NC score	0.196806 (rank : 233)
Query Neighborhood Hits	471	Target Neighborhood Hits	351	Shared Neighborhood Hits	146
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SNTB2_MOUSE
θ value	2.88788e-06 (rank : 189)	NC score	0.359049 (rank : 159)
Query Neighborhood Hits	471	Target Neighborhood Hits	181	Shared Neighborhood Hits	159
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG1_HUMAN
θ value	2.88788e-06 (rank : 190)	NC score	0.350512 (rank : 163)
Query Neighborhood Hits	471	Target Neighborhood Hits	181	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

GRASP_HUMAN
θ value	4.92598e-06 (rank : 191)	NC score	0.266861 (rank : 191)
Query Neighborhood Hits	471	Target Neighborhood Hits	147	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

SNTB2_HUMAN
θ value	8.40245e-06 (rank : 192)	NC score	0.357839 (rank : 160)
Query Neighborhood Hits	471	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

LRRC7_HUMAN
θ value	1.09739e-05 (rank : 193)	NC score	0.162433 (rank : 246)
Query Neighborhood Hits	471	Target Neighborhood Hits	423	Shared Neighborhood Hits	122
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

GRASP_MOUSE
θ value	1.43324e-05 (rank : 194)	NC score	0.263045 (rank : 192)
Query Neighborhood Hits	471	Target Neighborhood Hits	131	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

RIMS1_HUMAN
θ value	1.43324e-05 (rank : 195)	NC score	0.172937 (rank : 243)
Query Neighborhood Hits	471	Target Neighborhood Hits	437	Shared Neighborhood Hits	146
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

LRRC7_MOUSE
θ value	2.44474e-05 (rank : 196)	NC score	0.161235 (rank : 247)
Query Neighborhood Hits	471	Target Neighborhood Hits	416	Shared Neighborhood Hits	118
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

RPGF6_HUMAN
θ value	2.44474e-05 (rank : 197)	NC score	0.234078 (rank : 213)
Query Neighborhood Hits	471	Target Neighborhood Hits	266	Shared Neighborhood Hits	157
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

DSPP_HUMAN
θ value	3.19293e-05 (rank : 198)	NC score	0.058366 (rank : 323)
Query Neighborhood Hits	471	Target Neighborhood Hits	645	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MPP4_HUMAN
θ value	4.1701e-05 (rank : 199)	NC score	0.270899 (rank : 189)
Query Neighborhood Hits	471	Target Neighborhood Hits	205	Shared Neighborhood Hits	138
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PDZK4_MOUSE
θ value	4.1701e-05 (rank : 200)	NC score	0.273646 (rank : 186)
Query Neighborhood Hits	471	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

DSPP_MOUSE
θ value	7.1131e-05 (rank : 201)	NC score	0.062899 (rank : 311)
Query Neighborhood Hits	471	Target Neighborhood Hits	491	Shared Neighborhood Hits	65
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LAP2_HUMAN
θ value	7.1131e-05 (rank : 202)	NC score	0.153147 (rank : 251)
Query Neighborhood Hits	471	Target Neighborhood Hits	499	Shared Neighborhood Hits	116
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

SNTB1_HUMAN
θ value	7.1131e-05 (rank : 203)	NC score	0.336252 (rank : 171)
Query Neighborhood Hits	471	Target Neighborhood Hits	157	Shared Neighborhood Hits	148
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	7.1131e-05 (rank : 204)	NC score	0.335356 (rank : 172)
Query Neighborhood Hits	471	Target Neighborhood Hits	160	Shared Neighborhood Hits	146
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

LAP2_MOUSE
θ value	0.000121331 (rank : 205)	NC score	0.145951 (rank : 256)
Query Neighborhood Hits	471	Target Neighborhood Hits	482	Shared Neighborhood Hits	115
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PDZK4_HUMAN
θ value	0.000121331 (rank : 206)	NC score	0.272856 (rank : 187)
Query Neighborhood Hits	471	Target Neighborhood Hits	165	Shared Neighborhood Hits	116
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

MPP4_MOUSE
θ value	0.000158464 (rank : 207)	NC score	0.245036 (rank : 201)
Query Neighborhood Hits	471	Target Neighborhood Hits	188	Shared Neighborhood Hits	120
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

PDZD3_MOUSE
θ value	0.000158464 (rank : 208)	NC score	0.345515 (rank : 167)
Query Neighborhood Hits	471	Target Neighborhood Hits	171	Shared Neighborhood Hits	154
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SNTA1_HUMAN
θ value	0.000158464 (rank : 209)	NC score	0.347774 (rank : 165)
Query Neighborhood Hits	471	Target Neighborhood Hits	186	Shared Neighborhood Hits	163
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
θ value	0.000158464 (rank : 210)	NC score	0.341764 (rank : 168)
Query Neighborhood Hits	471	Target Neighborhood Hits	170	Shared Neighborhood Hits	157
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

APBA2_HUMAN
θ value	0.000786445 (rank : 211)	NC score	0.246849 (rank : 200)
Query Neighborhood Hits	471	Target Neighborhood Hits	220	Shared Neighborhood Hits	153
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.000786445 (rank : 212)	NC score	0.247372 (rank : 199)
Query Neighborhood Hits	471	Target Neighborhood Hits	219	Shared Neighborhood Hits	151
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

PCLO_MOUSE
θ value	0.00102713 (rank : 213)	NC score	0.125629 (rank : 266)
Query Neighborhood Hits	471	Target Neighborhood Hits	2275	Shared Neighborhood Hits	209
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TX1B3_HUMAN
θ value	0.00102713 (rank : 214)	NC score	0.382428 (rank : 146)
Query Neighborhood Hits	471	Target Neighborhood Hits	161	Shared Neighborhood Hits	148
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.00102713 (rank : 215)	NC score	0.379620 (rank : 147)
Query Neighborhood Hits	471	Target Neighborhood Hits	158	Shared Neighborhood Hits	145
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

ARHGB_HUMAN
θ value	0.00134147 (rank : 216)	NC score	0.204577 (rank : 229)
Query Neighborhood Hits	471	Target Neighborhood Hits	375	Shared Neighborhood Hits	167
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

MPP2_HUMAN
θ value	0.00134147 (rank : 217)	NC score	0.190071 (rank : 237)
Query Neighborhood Hits	471	Target Neighborhood Hits	173	Shared Neighborhood Hits	92
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

RPGF2_HUMAN
θ value	0.00134147 (rank : 218)	NC score	0.197914 (rank : 231)
Query Neighborhood Hits	471	Target Neighborhood Hits	242	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

PPRB_MOUSE
θ value	0.00228821 (rank : 219)	NC score	0.046216 (rank : 352)
Query Neighborhood Hits	471	Target Neighborhood Hits	354	Shared Neighborhood Hits	42
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RGS12_HUMAN
θ value	0.00228821 (rank : 220)	NC score	0.175228 (rank : 242)
Query Neighborhood Hits	471	Target Neighborhood Hits	333	Shared Neighborhood Hits	137
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

APBA1_HUMAN
θ value	0.00298849 (rank : 221)	NC score	0.254331 (rank : 196)
Query Neighborhood Hits	471	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

MPP5_HUMAN
θ value	0.00298849 (rank : 222)	NC score	0.253683 (rank : 197)
Query Neighborhood Hits	471	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.00298849 (rank : 223)	NC score	0.253015 (rank : 198)
Query Neighborhood Hits	471	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PDLI2_HUMAN
θ value	0.00298849 (rank : 224)	NC score	0.230281 (rank : 214)
Query Neighborhood Hits	471	Target Neighborhood Hits	245	Shared Neighborhood Hits	123
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PAR6G_HUMAN
θ value	0.00390308 (rank : 225)	NC score	0.243468 (rank : 204)
Query Neighborhood Hits	471	Target Neighborhood Hits	159	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	0.00390308 (rank : 226)	NC score	0.243609 (rank : 203)
Query Neighborhood Hits	471	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PICK1_MOUSE
θ value	0.00390308 (rank : 227)	NC score	0.257444 (rank : 194)
Query Neighborhood Hits	471	Target Neighborhood Hits	131	Shared Neighborhood Hits	121
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

HORN_MOUSE
θ value	0.00509761 (rank : 228)	NC score	0.030854 (rank : 367)
Query Neighborhood Hits	471	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

PICK1_HUMAN
θ value	0.00509761 (rank : 229)	NC score	0.257039 (rank : 195)
Query Neighborhood Hits	471	Target Neighborhood Hits	132	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

APXL_HUMAN
θ value	0.00665767 (rank : 230)	NC score	0.167418 (rank : 245)
Query Neighborhood Hits	471	Target Neighborhood Hits	553	Shared Neighborhood Hits	113
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BCLF1_HUMAN
θ value	0.00665767 (rank : 231)	NC score	0.040680 (rank : 357)
Query Neighborhood Hits	471	Target Neighborhood Hits	298	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

CHD9_MOUSE
θ value	0.00665767 (rank : 232)	NC score	0.023834 (rank : 378)
Query Neighborhood Hits	471	Target Neighborhood Hits	427	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

APBA3_HUMAN
θ value	0.0113563 (rank : 233)	NC score	0.238995 (rank : 209)
Query Neighborhood Hits	471	Target Neighborhood Hits	201	Shared Neighborhood Hits	144
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

BCLF1_MOUSE
θ value	0.0113563 (rank : 234)	NC score	0.042846 (rank : 354)
Query Neighborhood Hits	471	Target Neighborhood Hits	303	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

MPP2_MOUSE
θ value	0.0113563 (rank : 235)	NC score	0.190044 (rank : 238)
Query Neighborhood Hits	471	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

PAR6B_HUMAN
θ value	0.0113563 (rank : 236)	NC score	0.238994 (rank : 210)
Query Neighborhood Hits	471	Target Neighborhood Hits	126	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

AF9_HUMAN
θ value	0.0148317 (rank : 237)	NC score	0.038916 (rank : 358)
Query Neighborhood Hits	471	Target Neighborhood Hits	202	Shared Neighborhood Hits	22
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

PAR6A_MOUSE
θ value	0.0148317 (rank : 238)	NC score	0.229125 (rank : 217)
Query Neighborhood Hits	471	Target Neighborhood Hits	115	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6B_MOUSE
θ value	0.0148317 (rank : 239)	NC score	0.238350 (rank : 211)
Query Neighborhood Hits	471	Target Neighborhood Hits	128	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

CHD9_HUMAN
θ value	0.0193708 (rank : 240)	NC score	0.019325 (rank : 401)
Query Neighborhood Hits	471	Target Neighborhood Hits	343	Shared Neighborhood Hits	34
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

MPP3_HUMAN
θ value	0.0193708 (rank : 241)	NC score	0.242608 (rank : 205)
Query Neighborhood Hits	471	Target Neighborhood Hits	171	Shared Neighborhood Hits	135
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	0.0193708 (rank : 242)	NC score	0.244712 (rank : 202)
Query Neighborhood Hits	471	Target Neighborhood Hits	165	Shared Neighborhood Hits	134
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

PAR6A_HUMAN
θ value	0.0193708 (rank : 243)	NC score	0.228097 (rank : 219)
Query Neighborhood Hits	471	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

RHPN1_MOUSE
θ value	0.0252991 (rank : 244)	NC score	0.228388 (rank : 218)
Query Neighborhood Hits	471	Target Neighborhood Hits	154	Shared Neighborhood Hits	124
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SDCB1_HUMAN
θ value	0.0252991 (rank : 245)	NC score	0.229663 (rank : 216)
Query Neighborhood Hits	471	Target Neighborhood Hits	150	Shared Neighborhood Hits	139
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

DMP1_MOUSE
θ value	0.0330416 (rank : 246)	NC score	0.051141 (rank : 347)
Query Neighborhood Hits	471	Target Neighborhood Hits	498	Shared Neighborhood Hits	56
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

PDLI2_MOUSE
θ value	0.0330416 (rank : 247)	NC score	0.212419 (rank : 225)
Query Neighborhood Hits	471	Target Neighborhood Hits	220	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI4_MOUSE
θ value	0.0330416 (rank : 248)	NC score	0.149773 (rank : 252)
Query Neighborhood Hits	471	Target Neighborhood Hits	233	Shared Neighborhood Hits	107
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI5_HUMAN
θ value	0.0330416 (rank : 249)	NC score	0.113744 (rank : 273)
Query Neighborhood Hits	471	Target Neighborhood Hits	322	Shared Neighborhood Hits	122
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SDCB2_HUMAN
θ value	0.0330416 (rank : 250)	NC score	0.196088 (rank : 234)
Query Neighborhood Hits	471	Target Neighborhood Hits	121	Shared Neighborhood Hits	110
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

CDSN_MOUSE
θ value	0.0431538 (rank : 251)	NC score	0.033819 (rank : 364)
Query Neighborhood Hits	471	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

PPRB_HUMAN
θ value	0.0431538 (rank : 252)	NC score	0.042035 (rank : 355)
Query Neighborhood Hits	471	Target Neighborhood Hits	311	Shared Neighborhood Hits	40
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SRRM2_MOUSE
θ value	0.0431538 (rank : 253)	NC score	0.045711 (rank : 353)
Query Neighborhood Hits	471	Target Neighborhood Hits	1470	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

FILA_HUMAN
θ value	0.0563607 (rank : 254)	NC score	0.041415 (rank : 356)
Query Neighborhood Hits	471	Target Neighborhood Hits	685	Shared Neighborhood Hits	72
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

MAST4_HUMAN
θ value	0.0563607 (rank : 255)	NC score	0.026233 (rank : 373)
Query Neighborhood Hits	471	Target Neighborhood Hits	1804	Shared Neighborhood Hits	176
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MY18A_MOUSE
θ value	0.0563607 (rank : 256)	NC score	0.060397 (rank : 316)
Query Neighborhood Hits	471	Target Neighborhood Hits	1989	Shared Neighborhood Hits	204
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SRRM2_HUMAN
θ value	0.0563607 (rank : 257)	NC score	0.054516 (rank : 333)
Query Neighborhood Hits	471	Target Neighborhood Hits	1296	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DMP1_HUMAN
θ value	0.0736092 (rank : 258)	NC score	0.046739 (rank : 351)
Query Neighborhood Hits	471	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PDLI4_HUMAN
θ value	0.0736092 (rank : 259)	NC score	0.146280 (rank : 254)
Query Neighborhood Hits	471	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

APBA3_MOUSE
θ value	0.0961366 (rank : 260)	NC score	0.224323 (rank : 220)
Query Neighborhood Hits	471	Target Neighborhood Hits	174	Shared Neighborhood Hits	137
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PSCBP_MOUSE
θ value	0.0961366 (rank : 261)	NC score	0.218559 (rank : 222)
Query Neighborhood Hits	471	Target Neighborhood Hits	118	Shared Neighborhood Hits	107
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

SDCB1_MOUSE
θ value	0.0961366 (rank : 262)	NC score	0.229830 (rank : 215)
Query Neighborhood Hits	471	Target Neighborhood Hits	144	Shared Neighborhood Hits	131
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SPRL1_HUMAN
θ value	0.0961366 (rank : 263)	NC score	0.019559 (rank : 399)
Query Neighborhood Hits	471	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SYNP2_MOUSE
θ value	0.0961366 (rank : 264)	NC score	0.172147 (rank : 244)
Query Neighborhood Hits	471	Target Neighborhood Hits	252	Shared Neighborhood Hits	116
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

AP3B1_MOUSE
θ value	0.125558 (rank : 265)	NC score	0.016979 (rank : 404)
Query Neighborhood Hits	471	Target Neighborhood Hits	302	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CSPG2_HUMAN
θ value	0.125558 (rank : 266)	NC score	0.004119 (rank : 482)
Query Neighborhood Hits	471	Target Neighborhood Hits	681	Shared Neighborhood Hits	24
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

GIPC1_HUMAN
θ value	0.125558 (rank : 267)	NC score	0.140923 (rank : 257)
Query Neighborhood Hits	471	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

LIMK1_HUMAN
θ value	0.125558 (rank : 268)	NC score	0.009314 (rank : 449)
Query Neighborhood Hits	471	Target Neighborhood Hits	1005	Shared Neighborhood Hits	88
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

AUTS2_HUMAN
θ value	0.163984 (rank : 269)	NC score	0.023504 (rank : 380)
Query Neighborhood Hits	471	Target Neighborhood Hits	342	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

GIPC1_MOUSE
θ value	0.163984 (rank : 270)	NC score	0.146115 (rank : 255)
Query Neighborhood Hits	471	Target Neighborhood Hits	92	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

LIMK1_MOUSE
θ value	0.163984 (rank : 271)	NC score	0.008621 (rank : 453)
Query Neighborhood Hits	471	Target Neighborhood Hits	1008	Shared Neighborhood Hits	90
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

CEP35_HUMAN
θ value	0.21417 (rank : 272)	NC score	0.023392 (rank : 382)
Query Neighborhood Hits	471	Target Neighborhood Hits	811	Shared Neighborhood Hits	68
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CNKR2_HUMAN
θ value	0.21417 (rank : 273)	NC score	0.090059 (rank : 284)
Query Neighborhood Hits	471	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.21417 (rank : 274)	NC score	0.090145 (rank : 283)
Query Neighborhood Hits	471	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

LDB3_HUMAN
θ value	0.21417 (rank : 275)	NC score	0.120622 (rank : 268)
Query Neighborhood Hits	471	Target Neighborhood Hits	497	Shared Neighborhood Hits	110
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	0.21417 (rank : 276)	NC score	0.122086 (rank : 267)
Query Neighborhood Hits	471	Target Neighborhood Hits	510	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LIMK2_MOUSE
θ value	0.21417 (rank : 277)	NC score	0.011075 (rank : 438)
Query Neighborhood Hits	471	Target Neighborhood Hits	998	Shared Neighborhood Hits	77
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

PDLI5_MOUSE
θ value	0.21417 (rank : 278)	NC score	0.114403 (rank : 272)
Query Neighborhood Hits	471	Target Neighborhood Hits	287	Shared Neighborhood Hits	114
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PRP40_MOUSE
θ value	0.21417 (rank : 279)	NC score	0.023187 (rank : 385)
Query Neighborhood Hits	471	Target Neighborhood Hits	447	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RECQ4_MOUSE
θ value	0.21417 (rank : 280)	NC score	0.010439 (rank : 442)
Query Neighborhood Hits	471	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

TNC6B_HUMAN
θ value	0.21417 (rank : 281)	NC score	0.025973 (rank : 375)
Query Neighborhood Hits	471	Target Neighborhood Hits	256	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

MY18A_HUMAN
θ value	0.279714 (rank : 282)	NC score	0.057065 (rank : 325)
Query Neighborhood Hits	471	Target Neighborhood Hits	1929	Shared Neighborhood Hits	209
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PSCBP_HUMAN
θ value	0.279714 (rank : 283)	NC score	0.203856 (rank : 230)
Query Neighborhood Hits	471	Target Neighborhood Hits	123	Shared Neighborhood Hits	110
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

SI1L1_HUMAN
θ value	0.279714 (rank : 284)	NC score	0.035223 (rank : 363)
Query Neighborhood Hits	471	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SMDF_HUMAN
θ value	0.279714 (rank : 285)	NC score	0.019526 (rank : 400)
Query Neighborhood Hits	471	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

GIPC2_HUMAN
θ value	0.365318 (rank : 286)	NC score	0.120253 (rank : 269)
Query Neighborhood Hits	471	Target Neighborhood Hits	93	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

KRIT1_HUMAN
θ value	0.365318 (rank : 287)	NC score	0.069016 (rank : 301)
Query Neighborhood Hits	471	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

MP2K4_HUMAN
θ value	0.365318 (rank : 288)	NC score	-0.004813 (rank : 518)
Query Neighborhood Hits	471	Target Neighborhood Hits	832	Shared Neighborhood Hits	24
SwissProt Accessions	P45985, Q5U0B8	Gene names	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).

MP2K4_MOUSE
θ value	0.365318 (rank : 289)	NC score	-0.004785 (rank : 517)
Query Neighborhood Hits	471	Target Neighborhood Hits	833	Shared Neighborhood Hits	24
SwissProt Accessions	P47809	Gene names	Map2k4, Jnkk1, Prkmk4, Sek1, Serk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SEK1).

SDCB2_MOUSE
θ value	0.365318 (rank : 290)	NC score	0.195490 (rank : 235)
Query Neighborhood Hits	471	Target Neighborhood Hits	118	Shared Neighborhood Hits	111
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

ZCH10_MOUSE
θ value	0.365318 (rank : 291)	NC score	0.030578 (rank : 368)
Query Neighborhood Hits	471	Target Neighborhood Hits	133	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

CHD1_HUMAN
θ value	0.47712 (rank : 292)	NC score	0.015107 (rank : 412)
Query Neighborhood Hits	471	Target Neighborhood Hits	337	Shared Neighborhood Hits	33
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

KRIT1_MOUSE
θ value	0.47712 (rank : 293)	NC score	0.064394 (rank : 309)
Query Neighborhood Hits	471	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PACS1_HUMAN
θ value	0.47712 (rank : 294)	NC score	0.022819 (rank : 388)
Query Neighborhood Hits	471	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PDLI7_MOUSE
θ value	0.47712 (rank : 295)	NC score	0.094337 (rank : 281)
Query Neighborhood Hits	471	Target Neighborhood Hits	279	Shared Neighborhood Hits	96
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SYP2L_HUMAN
θ value	0.47712 (rank : 296)	NC score	0.190039 (rank : 239)
Query Neighborhood Hits	471	Target Neighborhood Hits	400	Shared Neighborhood Hits	118
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CC14B_MOUSE
θ value	0.62314 (rank : 297)	NC score	0.115299 (rank : 271)
Query Neighborhood Hits	471	Target Neighborhood Hits	103	Shared Neighborhood Hits	55
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DLGP4_HUMAN
θ value	0.62314 (rank : 298)	NC score	0.010154 (rank : 443)
Query Neighborhood Hits	471	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

DUS23_HUMAN
θ value	0.62314 (rank : 299)	NC score	0.217410 (rank : 223)
Query Neighborhood Hits	471	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

SFRS4_HUMAN
θ value	0.62314 (rank : 300)	NC score	0.011273 (rank : 437)
Query Neighborhood Hits	471	Target Neighborhood Hits	384	Shared Neighborhood Hits	33
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

BRCA2_MOUSE
θ value	0.813845 (rank : 301)	NC score	0.016830 (rank : 407)
Query Neighborhood Hits	471	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

CC14A_HUMAN
θ value	0.813845 (rank : 302)	NC score	0.104515 (rank : 276)
Query Neighborhood Hits	471	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
θ value	0.813845 (rank : 303)	NC score	0.105314 (rank : 275)
Query Neighborhood Hits	471	Target Neighborhood Hits	117	Shared Neighborhood Hits	58
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

NFAT5_HUMAN
θ value	0.813845 (rank : 304)	NC score	0.007003 (rank : 470)
Query Neighborhood Hits	471	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

PACS1_MOUSE
θ value	0.813845 (rank : 305)	NC score	0.022111 (rank : 391)
Query Neighborhood Hits	471	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

RHPN1_HUMAN
θ value	0.813845 (rank : 306)	NC score	0.211930 (rank : 226)
Query Neighborhood Hits	471	Target Neighborhood Hits	158	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SAPS3_HUMAN
θ value	0.813845 (rank : 307)	NC score	0.008781 (rank : 451)
Query Neighborhood Hits	471	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q5H9R7, Q3B7I1, Q3I4Y0, Q3KR35, Q68CR3, Q7L4R8, Q8N3B2, Q96MB2, Q9H2K5, Q9H2K6, Q9HCL4, Q9NUY3	Gene names	SAPS3, C11orf23, KIAA1558, PP6R3, SAPL
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3 (Sporulation-induced transcript 4- associated protein SAPL) (Protein phosphatase 6 regulatory subunit 3).

SFR17_HUMAN
θ value	0.813845 (rank : 308)	NC score	0.036171 (rank : 362)
Query Neighborhood Hits	471	Target Neighborhood Hits	325	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SI1L2_MOUSE
θ value	0.813845 (rank : 309)	NC score	0.037701 (rank : 359)
Query Neighborhood Hits	471	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

UBP47_MOUSE
θ value	0.813845 (rank : 310)	NC score	0.009479 (rank : 447)
Query Neighborhood Hits	471	Target Neighborhood Hits	135	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

K0528_MOUSE
θ value	1.06291 (rank : 311)	NC score	0.011877 (rank : 431)
Query Neighborhood Hits	471	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

NOLC1_HUMAN
θ value	1.06291 (rank : 312)	NC score	0.024861 (rank : 376)
Query Neighborhood Hits	471	Target Neighborhood Hits	452	Shared Neighborhood Hits	44
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PRAX_MOUSE
θ value	1.06291 (rank : 313)	NC score	0.065685 (rank : 307)
Query Neighborhood Hits	471	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SI1L2_HUMAN
θ value	1.06291 (rank : 314)	NC score	0.037021 (rank : 360)
Query Neighborhood Hits	471	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

TAOK1_HUMAN
θ value	1.06291 (rank : 315)	NC score	0.001020 (rank : 501)
Query Neighborhood Hits	471	Target Neighborhood Hits	1734	Shared Neighborhood Hits	72
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TAOK1_MOUSE
θ value	1.06291 (rank : 316)	NC score	0.001347 (rank : 498)
Query Neighborhood Hits	471	Target Neighborhood Hits	1720	Shared Neighborhood Hits	72
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

UBP47_HUMAN
θ value	1.06291 (rank : 317)	NC score	0.013392 (rank : 419)
Query Neighborhood Hits	471	Target Neighborhood Hits	149	Shared Neighborhood Hits	18
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

AFF4_MOUSE
θ value	1.38821 (rank : 318)	NC score	0.023827 (rank : 379)
Query Neighborhood Hits	471	Target Neighborhood Hits	581	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CHD1_MOUSE
θ value	1.38821 (rank : 319)	NC score	0.012398 (rank : 423)
Query Neighborhood Hits	471	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CSPG2_MOUSE
θ value	1.38821 (rank : 320)	NC score	0.007271 (rank : 467)
Query Neighborhood Hits	471	Target Neighborhood Hits	711	Shared Neighborhood Hits	33
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DEK_MOUSE
θ value	1.38821 (rank : 321)	NC score	0.026470 (rank : 372)
Query Neighborhood Hits	471	Target Neighborhood Hits	280	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DUS23_MOUSE
θ value	1.38821 (rank : 322)	NC score	0.224240 (rank : 221)
Query Neighborhood Hits	471	Target Neighborhood Hits	94	Shared Neighborhood Hits	57
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

GIPC3_HUMAN
θ value	1.38821 (rank : 323)	NC score	0.085244 (rank : 288)
Query Neighborhood Hits	471	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	1.38821 (rank : 324)	NC score	0.083925 (rank : 289)
Query Neighborhood Hits	471	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

LIMK2_HUMAN
θ value	1.38821 (rank : 325)	NC score	0.008247 (rank : 458)
Query Neighborhood Hits	471	Target Neighborhood Hits	986	Shared Neighborhood Hits	79
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

TAOK3_MOUSE
θ value	1.38821 (rank : 326)	NC score	-0.001407 (rank : 510)
Query Neighborhood Hits	471	Target Neighborhood Hits	1458	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

TCF20_MOUSE
θ value	1.38821 (rank : 327)	NC score	0.020775 (rank : 396)
Query Neighborhood Hits	471	Target Neighborhood Hits	396	Shared Neighborhood Hits	54
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

AKAP2_MOUSE
θ value	1.81305 (rank : 328)	NC score	0.023358 (rank : 384)
Query Neighborhood Hits	471	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

APC_MOUSE
θ value	1.81305 (rank : 329)	NC score	0.012576 (rank : 420)
Query Neighborhood Hits	471	Target Neighborhood Hits	441	Shared Neighborhood Hits	41
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ATBF1_MOUSE
θ value	1.81305 (rank : 330)	NC score	-0.007569 (rank : 524)
Query Neighborhood Hits	471	Target Neighborhood Hits	1841	Shared Neighborhood Hits	75
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATRX_MOUSE
θ value	1.81305 (rank : 331)	NC score	0.022161 (rank : 390)
Query Neighborhood Hits	471	Target Neighborhood Hits	682	Shared Neighborhood Hits	76
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CCD37_MOUSE
θ value	1.81305 (rank : 332)	NC score	0.021239 (rank : 394)
Query Neighborhood Hits	471	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CCD50_MOUSE
θ value	1.81305 (rank : 333)	NC score	0.024682 (rank : 377)
Query Neighborhood Hits	471	Target Neighborhood Hits	172	Shared Neighborhood Hits	24
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CSKP_HUMAN
θ value	1.81305 (rank : 334)	NC score	0.061268 (rank : 314)
Query Neighborhood Hits	471	Target Neighborhood Hits	1022	Shared Neighborhood Hits	133
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	1.81305 (rank : 335)	NC score	0.059077 (rank : 319)
Query Neighborhood Hits	471	Target Neighborhood Hits	1027	Shared Neighborhood Hits	132
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CUL4B_HUMAN
θ value	1.81305 (rank : 336)	NC score	0.004360 (rank : 481)
Query Neighborhood Hits	471	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

GIPC2_MOUSE
θ value	1.81305 (rank : 337)	NC score	0.079319 (rank : 290)
Query Neighborhood Hits	471	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GOG8A_HUMAN
θ value	1.81305 (rank : 338)	NC score	0.018582 (rank : 402)
Query Neighborhood Hits	471	Target Neighborhood Hits	635	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

PDZD6_HUMAN
θ value	1.81305 (rank : 339)	NC score	0.116133 (rank : 270)
Query Neighborhood Hits	471	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

SHAN2_MOUSE
θ value	1.81305 (rank : 340)	NC score	0.138113 (rank : 258)
Query Neighborhood Hits	471	Target Neighborhood Hits	446	Shared Neighborhood Hits	122
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

TAOK3_HUMAN
θ value	1.81305 (rank : 341)	NC score	-0.001743 (rank : 511)
Query Neighborhood Hits	471	Target Neighborhood Hits	1494	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TXND2_MOUSE
θ value	1.81305 (rank : 342)	NC score	0.029105 (rank : 369)
Query Neighborhood Hits	471	Target Neighborhood Hits	828	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

BMP2K_MOUSE
θ value	2.36792 (rank : 343)	NC score	-0.007108 (rank : 523)
Query Neighborhood Hits	471	Target Neighborhood Hits	874	Shared Neighborhood Hits	27
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CC14B_HUMAN
θ value	2.36792 (rank : 344)	NC score	0.112718 (rank : 274)
Query Neighborhood Hits	471	Target Neighborhood Hits	114	Shared Neighborhood Hits	60
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

K0319_MOUSE
θ value	2.36792 (rank : 345)	NC score	0.008552 (rank : 456)
Query Neighborhood Hits	471	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

KIF4A_HUMAN
θ value	2.36792 (rank : 346)	NC score	0.011566 (rank : 433)
Query Neighborhood Hits	471	Target Neighborhood Hits	1159	Shared Neighborhood Hits	62
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NCOR1_MOUSE
θ value	2.36792 (rank : 347)	NC score	0.019832 (rank : 398)
Query Neighborhood Hits	471	Target Neighborhood Hits	521	Shared Neighborhood Hits	54
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PHF2_MOUSE
θ value	2.36792 (rank : 348)	NC score	0.008571 (rank : 455)
Query Neighborhood Hits	471	Target Neighborhood Hits	241	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

RENT2_HUMAN
θ value	2.36792 (rank : 349)	NC score	0.020056 (rank : 397)
Query Neighborhood Hits	471	Target Neighborhood Hits	618	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RHG18_MOUSE
θ value	2.36792 (rank : 350)	NC score	0.003661 (rank : 486)
Query Neighborhood Hits	471	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RPTN_MOUSE
θ value	2.36792 (rank : 351)	NC score	0.020949 (rank : 395)
Query Neighborhood Hits	471	Target Neighborhood Hits	650	Shared Neighborhood Hits	57
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SC11A_HUMAN
θ value	2.36792 (rank : 352)	NC score	-0.000184 (rank : 505)
Query Neighborhood Hits	471	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SET1A_HUMAN
θ value	2.36792 (rank : 353)	NC score	0.016586 (rank : 409)
Query Neighborhood Hits	471	Target Neighborhood Hits	690	Shared Neighborhood Hits	46
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SHAN1_HUMAN
θ value	2.36792 (rank : 354)	NC score	0.097958 (rank : 280)
Query Neighborhood Hits	471	Target Neighborhood Hits	1041	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SYP2L_MOUSE
θ value	2.36792 (rank : 355)	NC score	0.137752 (rank : 259)
Query Neighborhood Hits	471	Target Neighborhood Hits	289	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TP4A3_MOUSE
θ value	2.36792 (rank : 356)	NC score	0.070695 (rank : 299)
Query Neighborhood Hits	471	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

ZCH10_HUMAN
θ value	2.36792 (rank : 357)	NC score	0.022945 (rank : 387)
Query Neighborhood Hits	471	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

ANK2_HUMAN
θ value	3.0926 (rank : 358)	NC score	0.009538 (rank : 446)
Query Neighborhood Hits	471	Target Neighborhood Hits	1615	Shared Neighborhood Hits	116
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CU055_HUMAN
θ value	3.0926 (rank : 359)	NC score	0.005566 (rank : 477)
Query Neighborhood Hits	471	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NX36	Gene names	C21orf55
Domain Architecture
Description	J domain-containing protein C21orf55.

DEK_HUMAN
θ value	3.0926 (rank : 360)	NC score	0.021691 (rank : 392)
Query Neighborhood Hits	471	Target Neighborhood Hits	199	Shared Neighborhood Hits	22
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

DPOLZ_HUMAN
θ value	3.0926 (rank : 361)	NC score	0.011066 (rank : 439)
Query Neighborhood Hits	471	Target Neighborhood Hits	200	Shared Neighborhood Hits	25
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

K1802_MOUSE
θ value	3.0926 (rank : 362)	NC score	-0.000429 (rank : 506)
Query Neighborhood Hits	471	Target Neighborhood Hits	1596	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAST3_HUMAN
θ value	3.0926 (rank : 363)	NC score	0.023371 (rank : 383)
Query Neighborhood Hits	471	Target Neighborhood Hits	1128	Shared Neighborhood Hits	133
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MUCDL_MOUSE
θ value	3.0926 (rank : 364)	NC score	0.007054 (rank : 469)
Query Neighborhood Hits	471	Target Neighborhood Hits	461	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PHF2_HUMAN
θ value	3.0926 (rank : 365)	NC score	0.007091 (rank : 468)
Query Neighborhood Hits	471	Target Neighborhood Hits	208	Shared Neighborhood Hits	14
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

WASF3_MOUSE
θ value	3.0926 (rank : 366)	NC score	0.012117 (rank : 427)
Query Neighborhood Hits	471	Target Neighborhood Hits	188	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ALMS1_HUMAN
θ value	4.03905 (rank : 367)	NC score	0.011933 (rank : 430)
Query Neighborhood Hits	471	Target Neighborhood Hits	356	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

CD2L1_MOUSE
θ value	4.03905 (rank : 368)	NC score	-0.005717 (rank : 519)
Query Neighborhood Hits	471	Target Neighborhood Hits	1463	Shared Neighborhood Hits	69
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CENPF_HUMAN
θ value	4.03905 (rank : 369)	NC score	0.014659 (rank : 413)
Query Neighborhood Hits	471	Target Neighborhood Hits	1932	Shared Neighborhood Hits	89
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

LRC27_HUMAN
θ value	4.03905 (rank : 370)	NC score	0.033349 (rank : 365)
Query Neighborhood Hits	471	Target Neighborhood Hits	710	Shared Neighborhood Hits	50
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

MAST2_HUMAN
θ value	4.03905 (rank : 371)	NC score	0.023432 (rank : 381)
Query Neighborhood Hits	471	Target Neighborhood Hits	1189	Shared Neighborhood Hits	137
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	4.03905 (rank : 372)	NC score	0.021442 (rank : 393)
Query Neighborhood Hits	471	Target Neighborhood Hits	1110	Shared Neighborhood Hits	134
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MRCKG_HUMAN
θ value	4.03905 (rank : 373)	NC score	-0.002384 (rank : 513)
Query Neighborhood Hits	471	Target Neighborhood Hits	1519	Shared Neighborhood Hits	62
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MYH8_MOUSE
θ value	4.03905 (rank : 374)	NC score	0.012361 (rank : 424)
Query Neighborhood Hits	471	Target Neighborhood Hits	1600	Shared Neighborhood Hits	72
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NKTR_MOUSE
θ value	4.03905 (rank : 375)	NC score	0.014318 (rank : 414)
Query Neighborhood Hits	471	Target Neighborhood Hits	417	Shared Neighborhood Hits	53
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NTKL_HUMAN
θ value	4.03905 (rank : 376)	NC score	0.008732 (rank : 452)
Query Neighborhood Hits	471	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

PRG4_HUMAN
θ value	4.03905 (rank : 377)	NC score	0.016480 (rank : 410)
Query Neighborhood Hits	471	Target Neighborhood Hits	764	Shared Neighborhood Hits	50
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RNPS1_HUMAN
θ value	4.03905 (rank : 378)	NC score	0.011327 (rank : 435)
Query Neighborhood Hits	471	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	4.03905 (rank : 379)	NC score	0.011327 (rank : 436)
Query Neighborhood Hits	471	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

RUVB2_HUMAN
θ value	4.03905 (rank : 380)	NC score	0.007709 (rank : 463)
Query Neighborhood Hits	471	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
θ value	4.03905 (rank : 381)	NC score	0.007723 (rank : 462)
Query Neighborhood Hits	471	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

SETBP_HUMAN
θ value	4.03905 (rank : 382)	NC score	0.009425 (rank : 448)
Query Neighborhood Hits	471	Target Neighborhood Hits	305	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SP4_MOUSE
θ value	4.03905 (rank : 383)	NC score	-0.011811 (rank : 525)
Query Neighborhood Hits	471	Target Neighborhood Hits	759	Shared Neighborhood Hits	12
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

SYCP2_HUMAN
θ value	4.03905 (rank : 384)	NC score	0.010819 (rank : 441)
Query Neighborhood Hits	471	Target Neighborhood Hits	230	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

TF7L2_HUMAN
θ value	4.03905 (rank : 385)	NC score	0.002587 (rank : 490)
Query Neighborhood Hits	471	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L2_MOUSE
θ value	4.03905 (rank : 386)	NC score	0.002710 (rank : 489)
Query Neighborhood Hits	471	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TRPM3_HUMAN
θ value	4.03905 (rank : 387)	NC score	0.002014 (rank : 492)
Query Neighborhood Hits	471	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPS1_MOUSE
θ value	4.03905 (rank : 388)	NC score	0.001770 (rank : 495)
Query Neighborhood Hits	471	Target Neighborhood Hits	609	Shared Neighborhood Hits	15
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

UBP36_HUMAN
θ value	4.03905 (rank : 389)	NC score	0.003144 (rank : 488)
Query Neighborhood Hits	471	Target Neighborhood Hits	232	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

WASF3_HUMAN
θ value	4.03905 (rank : 390)	NC score	0.009628 (rank : 444)
Query Neighborhood Hits	471	Target Neighborhood Hits	204	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

CCD46_MOUSE
θ value	5.27518 (rank : 391)	NC score	0.016866 (rank : 406)
Query Neighborhood Hits	471	Target Neighborhood Hits	1405	Shared Neighborhood Hits	80
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CHD2_HUMAN
θ value	5.27518 (rank : 392)	NC score	0.012290 (rank : 425)
Query Neighborhood Hits	471	Target Neighborhood Hits	360	Shared Neighborhood Hits	38
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CMGA_MOUSE
θ value	5.27518 (rank : 393)	NC score	0.013605 (rank : 418)
Query Neighborhood Hits	471	Target Neighborhood Hits	172	Shared Neighborhood Hits	24
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

G3BP_HUMAN
θ value	5.27518 (rank : 394)	NC score	0.001578 (rank : 496)
Query Neighborhood Hits	471	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

GRLF1_HUMAN
θ value	5.27518 (rank : 395)	NC score	0.001497 (rank : 497)
Query Neighborhood Hits	471	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

LRRN3_MOUSE
θ value	5.27518 (rank : 396)	NC score	0.008608 (rank : 454)
Query Neighborhood Hits	471	Target Neighborhood Hits	455	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

NPM2_MOUSE
θ value	5.27518 (rank : 397)	NC score	0.007420 (rank : 464)
Query Neighborhood Hits	471	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W85, Q8BW23	Gene names	Npm2
Domain Architecture
Description	Nucleoplasmin-2.

PDLI3_HUMAN
θ value	5.27518 (rank : 398)	NC score	0.148354 (rank : 253)
Query Neighborhood Hits	471	Target Neighborhood Hits	199	Shared Neighborhood Hits	103
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PRAX_HUMAN
θ value	5.27518 (rank : 399)	NC score	0.050505 (rank : 348)
Query Neighborhood Hits	471	Target Neighborhood Hits	215	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

RAI1_HUMAN
θ value	5.27518 (rank : 400)	NC score	0.011770 (rank : 432)
Query Neighborhood Hits	471	Target Neighborhood Hits	360	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RASN_HUMAN
θ value	5.27518 (rank : 401)	NC score	-0.006040 (rank : 521)
Query Neighborhood Hits	471	Target Neighborhood Hits	259	Shared Neighborhood Hits	4
SwissProt Accessions	P01111, Q14971, Q15104, Q15282	Gene names	NRAS
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

RASN_MOUSE
θ value	5.27518 (rank : 402)	NC score	-0.006039 (rank : 520)
Query Neighborhood Hits	471	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P08556	Gene names	Nras
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

RGP1_HUMAN
θ value	5.27518 (rank : 403)	NC score	0.005231 (rank : 478)
Query Neighborhood Hits	471	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RHG12_MOUSE
θ value	5.27518 (rank : 404)	NC score	0.003872 (rank : 484)
Query Neighborhood Hits	471	Target Neighborhood Hits	204	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SLK_MOUSE
θ value	5.27518 (rank : 405)	NC score	-0.001251 (rank : 509)
Query Neighborhood Hits	471	Target Neighborhood Hits	1798	Shared Neighborhood Hits	80
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TP4A2_HUMAN
θ value	5.27518 (rank : 406)	NC score	0.076852 (rank : 291)
Query Neighborhood Hits	471	Target Neighborhood Hits	56	Shared Neighborhood Hits	35
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	5.27518 (rank : 407)	NC score	0.076852 (rank : 292)
Query Neighborhood Hits	471	Target Neighborhood Hits	56	Shared Neighborhood Hits	35
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

TPP2_HUMAN
θ value	5.27518 (rank : 408)	NC score	0.009607 (rank : 445)
Query Neighborhood Hits	471	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P29144	Gene names	TPP2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

TPP2_MOUSE
θ value	5.27518 (rank : 409)	NC score	0.008882 (rank : 450)
Query Neighborhood Hits	471	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q64514	Gene names	Tpp2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

UBP34_HUMAN
θ value	5.27518 (rank : 410)	NC score	0.007310 (rank : 466)
Query Neighborhood Hits	471	Target Neighborhood Hits	210	Shared Neighborhood Hits	19
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	5.27518 (rank : 411)	NC score	0.007353 (rank : 465)
Query Neighborhood Hits	471	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

ZCH11_HUMAN
θ value	5.27518 (rank : 412)	NC score	0.011508 (rank : 434)
Query Neighborhood Hits	471	Target Neighborhood Hits	278	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ACINU_MOUSE
θ value	6.88961 (rank : 413)	NC score	0.012182 (rank : 426)
Query Neighborhood Hits	471	Target Neighborhood Hits	712	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AKA12_HUMAN
θ value	6.88961 (rank : 414)	NC score	0.026782 (rank : 371)
Query Neighborhood Hits	471	Target Neighborhood Hits	825	Shared Neighborhood Hits	68
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ANR26_MOUSE
θ value	6.88961 (rank : 415)	NC score	0.012040 (rank : 429)
Query Neighborhood Hits	471	Target Neighborhood Hits	1554	Shared Neighborhood Hits	70
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AP3B1_HUMAN
θ value	6.88961 (rank : 416)	NC score	0.012441 (rank : 422)
Query Neighborhood Hits	471	Target Neighborhood Hits	283	Shared Neighborhood Hits	32
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CI079_HUMAN
θ value	6.88961 (rank : 417)	NC score	0.013901 (rank : 416)
Query Neighborhood Hits	471	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CIR_HUMAN
θ value	6.88961 (rank : 418)	NC score	0.012114 (rank : 428)
Query Neighborhood Hits	471	Target Neighborhood Hits	249	Shared Neighborhood Hits	29
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

DC1I2_MOUSE
θ value	6.88961 (rank : 419)	NC score	0.001185 (rank : 499)
Query Neighborhood Hits	471	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

DGKH_HUMAN
θ value	6.88961 (rank : 420)	NC score	0.002276 (rank : 491)
Query Neighborhood Hits	471	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

EM55_MOUSE
θ value	6.88961 (rank : 421)	NC score	0.207931 (rank : 228)
Query Neighborhood Hits	471	Target Neighborhood Hits	221	Shared Neighborhood Hits	127
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

EXO1_MOUSE
θ value	6.88961 (rank : 422)	NC score	0.012568 (rank : 421)
Query Neighborhood Hits	471	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

GOGA5_HUMAN
θ value	6.88961 (rank : 423)	NC score	0.022816 (rank : 389)
Query Neighborhood Hits	471	Target Neighborhood Hits	1168	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

LMO7_HUMAN
θ value	6.88961 (rank : 424)	NC score	0.061516 (rank : 313)
Query Neighborhood Hits	471	Target Neighborhood Hits	507	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MPP6_HUMAN
θ value	6.88961 (rank : 425)	NC score	0.179242 (rank : 241)
Query Neighborhood Hits	471	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	6.88961 (rank : 426)	NC score	0.181558 (rank : 240)
Query Neighborhood Hits	471	Target Neighborhood Hits	187	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

NFAC1_HUMAN
θ value	6.88961 (rank : 427)	NC score	0.006421 (rank : 473)
Query Neighborhood Hits	471	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PCDBB_HUMAN
θ value	6.88961 (rank : 428)	NC score	-0.004703 (rank : 515)
Query Neighborhood Hits	471	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5F2	Gene names	PCDHB11
Domain Architecture
Description	Protocadherin beta 11 precursor (PCDH-beta11).

PCDBC_HUMAN
θ value	6.88961 (rank : 429)	NC score	-0.004719 (rank : 516)
Query Neighborhood Hits	471	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5F1	Gene names	PCDHB12
Domain Architecture
Description	Protocadherin beta 12 precursor (PCDH-beta12).

PDLI3_MOUSE
θ value	6.88961 (rank : 430)	NC score	0.137102 (rank : 260)
Query Neighborhood Hits	471	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PO5FN_HUMAN
θ value	6.88961 (rank : 431)	NC score	-0.001145 (rank : 508)
Query Neighborhood Hits	471	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZW0	Gene names	POU5FLC1
Domain Architecture
Description	POU domain, class 5, transcription factor 1-like protein 3.

PSMD9_HUMAN
θ value	6.88961 (rank : 432)	NC score	0.036250 (rank : 361)
Query Neighborhood Hits	471	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

RFIP1_HUMAN
θ value	6.88961 (rank : 433)	NC score	0.008319 (rank : 457)
Query Neighborhood Hits	471	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SHAN2_HUMAN
θ value	6.88961 (rank : 434)	NC score	0.154445 (rank : 250)
Query Neighborhood Hits	471	Target Neighborhood Hits	346	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SI1L3_HUMAN
θ value	6.88961 (rank : 435)	NC score	0.028050 (rank : 370)
Query Neighborhood Hits	471	Target Neighborhood Hits	305	Shared Neighborhood Hits	52
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SPTB1_HUMAN
θ value	6.88961 (rank : 436)	NC score	0.001935 (rank : 493)
Query Neighborhood Hits	471	Target Neighborhood Hits	541	Shared Neighborhood Hits	31
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

STK10_HUMAN
θ value	6.88961 (rank : 437)	NC score	0.000458 (rank : 503)
Query Neighborhood Hits	471	Target Neighborhood Hits	1921	Shared Neighborhood Hits	81
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TYDP1_MOUSE
θ value	6.88961 (rank : 438)	NC score	0.006262 (rank : 474)
Query Neighborhood Hits	471	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJ37, Q8VE39	Gene names	Tdp1
Domain Architecture
Description	Tyrosyl-DNA phosphodiesterase 1 (EC 3.1.4.-) (Tyr-DNA phosphodiesterase 1).

YAF2_MOUSE
θ value	6.88961 (rank : 439)	NC score	0.005184 (rank : 479)
Query Neighborhood Hits	471	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LW6, Q3UFD4, Q9DBE4	Gene names	Yaf2
Domain Architecture
Description	YY1-associated factor 2.

ANKZ1_HUMAN
θ value	8.99809 (rank : 440)	NC score	0.001896 (rank : 494)
Query Neighborhood Hits	471	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANR18_HUMAN
θ value	8.99809 (rank : 441)	NC score	0.006912 (rank : 471)
Query Neighborhood Hits	471	Target Neighborhood Hits	1106	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ARI4A_HUMAN
θ value	8.99809 (rank : 442)	NC score	0.007825 (rank : 461)
Query Neighborhood Hits	471	Target Neighborhood Hits	434	Shared Neighborhood Hits	42
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ATL2_MOUSE
θ value	8.99809 (rank : 443)	NC score	-0.002131 (rank : 512)
Query Neighborhood Hits	471	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

CCD37_HUMAN
θ value	8.99809 (rank : 444)	NC score	0.014112 (rank : 415)
Query Neighborhood Hits	471	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CREB5_HUMAN
θ value	8.99809 (rank : 445)	NC score	0.001167 (rank : 500)
Query Neighborhood Hits	471	Target Neighborhood Hits	222	Shared Neighborhood Hits	9
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

DCP1A_MOUSE
θ value	8.99809 (rank : 446)	NC score	0.006026 (rank : 476)
Query Neighborhood Hits	471	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

DDX21_HUMAN
θ value	8.99809 (rank : 447)	NC score	0.000770 (rank : 502)
Query Neighborhood Hits	471	Target Neighborhood Hits	308	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DMRTA_HUMAN
θ value	8.99809 (rank : 448)	NC score	0.003972 (rank : 483)
Query Neighborhood Hits	471	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

DUS5_HUMAN
θ value	8.99809 (rank : 449)	NC score	0.016869 (rank : 405)
Query Neighborhood Hits	471	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

EM55_HUMAN
θ value	8.99809 (rank : 450)	NC score	0.209379 (rank : 227)
Query Neighborhood Hits	471	Target Neighborhood Hits	228	Shared Neighborhood Hits	129
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

F120A_HUMAN
θ value	8.99809 (rank : 451)	NC score	0.003219 (rank : 487)
Query Neighborhood Hits	471	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZB2, O60649, Q14688, Q4VXF4, Q4VXF5, Q4VXG2, Q96I21, Q9NZB1	Gene names	FAM120A, C9orf10, KIAA0183
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120A.

GLIS3_HUMAN
θ value	8.99809 (rank : 452)	NC score	-0.013052 (rank : 526)
Query Neighborhood Hits	471	Target Neighborhood Hits	758	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

K1C18_HUMAN
θ value	8.99809 (rank : 453)	NC score	-0.000150 (rank : 504)
Query Neighborhood Hits	471	Target Neighborhood Hits	441	Shared Neighborhood Hits	26
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

LSR_HUMAN
θ value	8.99809 (rank : 454)	NC score	0.006221 (rank : 475)
Query Neighborhood Hits	471	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

MYH1_MOUSE
θ value	8.99809 (rank : 455)	NC score	0.008142 (rank : 459)
Query Neighborhood Hits	471	Target Neighborhood Hits	1461	Shared Neighborhood Hits	61
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_HUMAN
θ value	8.99809 (rank : 456)	NC score	0.006749 (rank : 472)
Query Neighborhood Hits	471	Target Neighborhood Hits	1377	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH8_HUMAN
θ value	8.99809 (rank : 457)	NC score	0.011008 (rank : 440)
Query Neighborhood Hits	471	Target Neighborhood Hits	1610	Shared Neighborhood Hits	73
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYST4_HUMAN
θ value	8.99809 (rank : 458)	NC score	0.008007 (rank : 460)
Query Neighborhood Hits	471	Target Neighborhood Hits	671	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYT1_HUMAN
θ value	8.99809 (rank : 459)	NC score	0.004982 (rank : 480)
Query Neighborhood Hits	471	Target Neighborhood Hits	475	Shared Neighborhood Hits	34
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NID2_HUMAN
θ value	8.99809 (rank : 460)	NC score	-0.004581 (rank : 514)
Query Neighborhood Hits	471	Target Neighborhood Hits	456	Shared Neighborhood Hits	9
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NKTR_HUMAN
θ value	8.99809 (rank : 461)	NC score	0.023079 (rank : 386)
Query Neighborhood Hits	471	Target Neighborhood Hits	658	Shared Neighborhood Hits	76
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PAX3_HUMAN
θ value	8.99809 (rank : 462)	NC score	-0.006464 (rank : 522)
Query Neighborhood Hits	471	Target Neighborhood Hits	513	Shared Neighborhood Hits	14
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

SAMD4_MOUSE
θ value	8.99809 (rank : 463)	NC score	0.003709 (rank : 485)
Query Neighborhood Hits	471	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

SI1L1_MOUSE
θ value	8.99809 (rank : 464)	NC score	0.032570 (rank : 366)
Query Neighborhood Hits	471	Target Neighborhood Hits	189	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SIPA1_HUMAN
θ value	8.99809 (rank : 465)	NC score	0.026003 (rank : 374)
Query Neighborhood Hits	471	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SMC1A_HUMAN
θ value	8.99809 (rank : 466)	NC score	0.017543 (rank : 403)
Query Neighborhood Hits	471	Target Neighborhood Hits	1346	Shared Neighborhood Hits	64
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	8.99809 (rank : 467)	NC score	0.016607 (rank : 408)
Query Neighborhood Hits	471	Target Neighborhood Hits	1384	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMUF1_HUMAN
θ value	8.99809 (rank : 468)	NC score	0.013873 (rank : 417)
Query Neighborhood Hits	471	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	8.99809 (rank : 469)	NC score	0.015176 (rank : 411)
Query Neighborhood Hits	471	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

TP4A3_HUMAN
θ value	8.99809 (rank : 470)	NC score	0.075278 (rank : 294)
Query Neighborhood Hits	471	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TSH3_MOUSE
θ value	8.99809 (rank : 471)	NC score	-0.000690 (rank : 507)
Query Neighborhood Hits	471	Target Neighborhood Hits	590	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

CA106_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.056042 (rank : 331)
Query Neighborhood Hits	471	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.054445 (rank : 334)
Query Neighborhood Hits	471	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CAR11_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.058582 (rank : 321)
Query Neighborhood Hits	471	Target Neighborhood Hits	690	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CDKN3_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.058452 (rank : 322)
Query Neighborhood Hits	471	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

CNTN2_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.050445 (rank : 349)
Query Neighborhood Hits	471	Target Neighborhood Hits	440	Shared Neighborhood Hits	15
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.050342 (rank : 350)
Query Neighborhood Hits	471	Target Neighborhood Hits	450	Shared Neighborhood Hits	14
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN5_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.052264 (rank : 342)
Query Neighborhood Hits	471	Target Neighborhood Hits	446	Shared Neighborhood Hits	18
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN5_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.051264 (rank : 346)
Query Neighborhood Hits	471	Target Neighborhood Hits	434	Shared Neighborhood Hits	21
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CO7A1_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.053320 (rank : 340)
Query Neighborhood Hits	471	Target Neighborhood Hits	807	Shared Neighborhood Hits	41
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COCA1_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.065339 (rank : 308)
Query Neighborhood Hits	471	Target Neighborhood Hits	458	Shared Neighborhood Hits	28
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.066860 (rank : 305)
Query Neighborhood Hits	471	Target Neighborhood Hits	467	Shared Neighborhood Hits	26
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.054441 (rank : 335)
Query Neighborhood Hits	471	Target Neighborhood Hits	402	Shared Neighborhood Hits	22
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DCC_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.075611 (rank : 293)
Query Neighborhood Hits	471	Target Neighborhood Hits	583	Shared Neighborhood Hits	34
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.074017 (rank : 296)
Query Neighborhood Hits	471	Target Neighborhood Hits	896	Shared Neighborhood Hits	50
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DSCAM_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.053649 (rank : 339)
Query Neighborhood Hits	471	Target Neighborhood Hits	524	Shared Neighborhood Hits	21
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.054083 (rank : 337)
Query Neighborhood Hits	471	Target Neighborhood Hits	589	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

FINC_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.101975 (rank : 277)
Query Neighborhood Hits	471	Target Neighborhood Hits	302	Shared Neighborhood Hits	25
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.100602 (rank : 278)
Query Neighborhood Hits	471	Target Neighborhood Hits	309	Shared Neighborhood Hits	24
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FNDC3_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.091927 (rank : 282)
Query Neighborhood Hits	471	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.085672 (rank : 287)
Query Neighborhood Hits	471	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ITB4_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.056789 (rank : 327)
Query Neighborhood Hits	471	Target Neighborhood Hits	458	Shared Neighborhood Hits	21
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KGUA_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.133774 (rank : 262)
Query Neighborhood Hits	471	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.134237 (rank : 261)
Query Neighborhood Hits	471	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

L1CAM_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.054245 (rank : 336)
Query Neighborhood Hits	471	Target Neighborhood Hits	457	Shared Neighborhood Hits	16
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.054681 (rank : 332)
Query Neighborhood Hits	471	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

MAMC2_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.066841 (rank : 306)
Query Neighborhood Hits	471	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.069737 (rank : 300)
Query Neighborhood Hits	471	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MDGA1_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.051541 (rank : 345)
Query Neighborhood Hits	471	Target Neighborhood Hits	358	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

NEO1_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.071463 (rank : 298)
Query Neighborhood Hits	471	Target Neighborhood Hits	530	Shared Neighborhood Hits	35
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.074297 (rank : 295)
Query Neighborhood Hits	471	Target Neighborhood Hits	523	Shared Neighborhood Hits	38
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NRCAM_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.052246 (rank : 343)
Query Neighborhood Hits	471	Target Neighborhood Hits	439	Shared Neighborhood Hits	15
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.054081 (rank : 338)
Query Neighborhood Hits	471	Target Neighborhood Hits	432	Shared Neighborhood Hits	17
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PDLI1_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.128243 (rank : 265)
Query Neighborhood Hits	471	Target Neighborhood Hits	242	Shared Neighborhood Hits	98
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.131599 (rank : 264)
Query Neighborhood Hits	471	Target Neighborhood Hits	213	Shared Neighborhood Hits	98
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI7_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.100006 (rank : 279)
Query Neighborhood Hits	471	Target Neighborhood Hits	547	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZD8_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.056441 (rank : 329)
Query Neighborhood Hits	471	Target Neighborhood Hits	185	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PTEN_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.068250 (rank : 303)
Query Neighborhood Hits	471	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.068247 (rank : 304)
Query Neighborhood Hits	471	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

RES18_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.053286 (rank : 341)
Query Neighborhood Hits	471	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

RHPN2_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.072778 (rank : 297)
Query Neighborhood Hits	471	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

SDK1_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.059231 (rank : 318)
Query Neighborhood Hits	471	Target Neighborhood Hits	511	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.060268 (rank : 317)
Query Neighborhood Hits	471	Target Neighborhood Hits	495	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.060563 (rank : 315)
Query Neighborhood Hits	471	Target Neighborhood Hits	495	Shared Neighborhood Hits	28
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.063109 (rank : 310)
Query Neighborhood Hits	471	Target Neighborhood Hits	480	Shared Neighborhood Hits	29
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SYNP2_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.131974 (rank : 263)
Query Neighborhood Hits	471	Target Neighborhood Hits	323	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TARSH_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.056147 (rank : 330)
Query Neighborhood Hits	471	Target Neighborhood Hits	768	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TENN_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.058163 (rank : 324)
Query Neighborhood Hits	471	Target Neighborhood Hits	453	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.068528 (rank : 302)
Query Neighborhood Hits	471	Target Neighborhood Hits	484	Shared Neighborhood Hits	23
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.056862 (rank : 326)
Query Neighborhood Hits	471	Target Neighborhood Hits	526	Shared Neighborhood Hits	23
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.056559 (rank : 328)
Query Neighborhood Hits	471	Target Neighborhood Hits	531	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TIAM1_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.051711 (rank : 344)
Query Neighborhood Hits	471	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TP4A1_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.089445 (rank : 285)
Query Neighborhood Hits	471	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.089445 (rank : 286)
Query Neighborhood Hits	471	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

USH2A_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.061860 (rank : 312)
Query Neighborhood Hits	471	Target Neighborhood Hits	600	Shared Neighborhood Hits	30
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.058618 (rank : 320)
Query Neighborhood Hits	471	Target Neighborhood Hits	626	Shared Neighborhood Hits	25
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

Hits sorted by NC score

PTN13_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	471	Target Neighborhood Hits	471	Shared Neighborhood Hits	471
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
NC score	0.990296 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	471	Target Neighborhood Hits	426	Shared Neighborhood Hits	314
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN3_HUMAN
NC score	0.867212 (rank : 3)	θ value	5.20228e-48 (rank : 3)
Query Neighborhood Hits	471	Target Neighborhood Hits	258	Shared Neighborhood Hits	218
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
NC score	0.862901 (rank : 4)	θ value	4.40402e-47 (rank : 5)
Query Neighborhood Hits	471	Target Neighborhood Hits	303	Shared Neighborhood Hits	226
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN21_MOUSE
NC score	0.804840 (rank : 5)	θ value	2.26182e-43 (rank : 19)
Query Neighborhood Hits	471	Target Neighborhood Hits	155	Shared Neighborhood Hits	105
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.804710 (rank : 6)	θ value	5.03882e-43 (rank : 21)
Query Neighborhood Hits	471	Target Neighborhood Hits	143	Shared Neighborhood Hits	104
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_HUMAN
NC score	0.804429 (rank : 7)	θ value	1.91475e-42 (rank : 24)
Query Neighborhood Hits	471	Target Neighborhood Hits	163	Shared Neighborhood Hits	112
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
NC score	0.804274 (rank : 8)	θ value	1.62093e-41 (rank : 27)
Query Neighborhood Hits	471	Target Neighborhood Hits	142	Shared Neighborhood Hits	107
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN2_MOUSE
NC score	0.722059 (rank : 9)	θ value	3.85808e-43 (rank : 20)
Query Neighborhood Hits	471	Target Neighborhood Hits	107	Shared Neighborhood Hits	68
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.722019 (rank : 10)	θ value	6.58091e-43 (rank : 22)
Query Neighborhood Hits	471	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN2_HUMAN
NC score	0.721542 (rank : 11)	θ value	4.2656e-42 (rank : 26)
Query Neighborhood Hits	471	Target Neighborhood Hits	92	Shared Neighborhood Hits	68
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN1_HUMAN
NC score	0.721525 (rank : 12)	θ value	8.59492e-43 (rank : 23)
Query Neighborhood Hits	471	Target Neighborhood Hits	84	Shared Neighborhood Hits	65
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN18_HUMAN
NC score	0.720911 (rank : 13)	θ value	1.98146e-39 (rank : 38)
Query Neighborhood Hits	471	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN7_MOUSE
NC score	0.718987 (rank : 14)	θ value	4.41421e-39 (rank : 40)
Query Neighborhood Hits	471	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN7_HUMAN
NC score	0.718381 (rank : 15)	θ value	4.41421e-39 (rank : 39)
Query Neighborhood Hits	471	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN18_MOUSE
NC score	0.718136 (rank : 16)	θ value	7.04741e-37 (rank : 44)
Query Neighborhood Hits	471	Target Neighborhood Hits	134	Shared Neighborhood Hits	73
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN12_HUMAN
NC score	0.714310 (rank : 17)	θ value	2.11701e-41 (rank : 28)
Query Neighborhood Hits	471	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
NC score	0.713658 (rank : 18)	θ value	8.04462e-41 (rank : 33)
Query Neighborhood Hits	471	Target Neighborhood Hits	123	Shared Neighborhood Hits	72
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN22_HUMAN
NC score	0.712912 (rank : 19)	θ value	2.19075e-38 (rank : 42)
Query Neighborhood Hits	471	Target Neighborhood Hits	109	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
NC score	0.708701 (rank : 20)	θ value	9.83387e-39 (rank : 41)
Query Neighborhood Hits	471	Target Neighborhood Hits	179	Shared Neighborhood Hits	74
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN5_MOUSE
NC score	0.708541 (rank : 21)	θ value	2.59387e-31 (rank : 65)
Query Neighborhood Hits	471	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.708533 (rank : 22)	θ value	7.54701e-31 (rank : 67)
Query Neighborhood Hits	471	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRO_HUMAN
NC score	0.708365 (rank : 23)	θ value	8.89434e-40 (rank : 37)
Query Neighborhood Hits	471	Target Neighborhood Hits	139	Shared Neighborhood Hits	71
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
NC score	0.708023 (rank : 24)	θ value	5.96599e-36 (rank : 49)
Query Neighborhood Hits	471	Target Neighborhood Hits	77	Shared Neighborhood Hits	70
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
NC score	0.706412 (rank : 25)	θ value	1.46948e-34 (rank : 55)
Query Neighborhood Hits	471	Target Neighborhood Hits	84	Shared Neighborhood Hits	68
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPR2_HUMAN
NC score	0.704276 (rank : 26)	θ value	1.12514e-34 (rank : 54)
Query Neighborhood Hits	471	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTN9_MOUSE
NC score	0.703586 (rank : 27)	θ value	2.05049e-36 (rank : 46)
Query Neighborhood Hits	471	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_HUMAN
NC score	0.703440 (rank : 28)	θ value	1.20211e-36 (rank : 45)
Query Neighborhood Hits	471	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

CD45_MOUSE
NC score	0.703424 (rank : 29)	θ value	5.21438e-40 (rank : 36)
Query Neighborhood Hits	471	Target Neighborhood Hits	178	Shared Neighborhood Hits	70
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPR2_MOUSE
NC score	0.703133 (rank : 30)	θ value	6.59618e-35 (rank : 53)
Query Neighborhood Hits	471	Target Neighborhood Hits	120	Shared Neighborhood Hits	69
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRE_HUMAN
NC score	0.702452 (rank : 31)	θ value	4.71619e-41 (rank : 30)
Query Neighborhood Hits	471	Target Neighborhood Hits	92	Shared Neighborhood Hits	69
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
NC score	0.702392 (rank : 32)	θ value	6.15952e-41 (rank : 32)
Query Neighborhood Hits	471	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.701551 (rank : 33)	θ value	1.05066e-40 (rank : 34)
Query Neighborhood Hits	471	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRN_HUMAN
NC score	0.700521 (rank : 34)	θ value	5.96599e-36 (rank : 48)
Query Neighborhood Hits	471	Target Neighborhood Hits	156	Shared Neighborhood Hits	68
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRA_MOUSE
NC score	0.699460 (rank : 35)	θ value	7.79185e-36 (rank : 50)
Query Neighborhood Hits	471	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

CD45_HUMAN
NC score	0.698985 (rank : 36)	θ value	1.79215e-40 (rank : 35)
Query Neighborhood Hits	471	Target Neighborhood Hits	243	Shared Neighborhood Hits	78
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRN_MOUSE
NC score	0.697777 (rank : 37)	θ value	2.67802e-36 (rank : 47)
Query Neighborhood Hits	471	Target Neighborhood Hits	240	Shared Neighborhood Hits	73
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRJ_MOUSE
NC score	0.688321 (rank : 38)	θ value	1.01529e-43 (rank : 18)
Query Neighborhood Hits	471	Target Neighborhood Hits	188	Shared Neighborhood Hits	70
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRJ_HUMAN
NC score	0.685320 (rank : 39)	θ value	2.67181e-44 (rank : 15)
Query Neighborhood Hits	471	Target Neighborhood Hits	207	Shared Neighborhood Hits	76
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN6_HUMAN
NC score	0.680073 (rank : 40)	θ value	8.30557e-46 (rank : 7)
Query Neighborhood Hits	471	Target Neighborhood Hits	234	Shared Neighborhood Hits	71
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTPRV_MOUSE
NC score	0.678881 (rank : 41)	θ value	2.19075e-38 (rank : 43)
Query Neighborhood Hits	471	Target Neighborhood Hits	179	Shared Neighborhood Hits	68
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN6_MOUSE
NC score	0.678313 (rank : 42)	θ value	1.51363e-47 (rank : 4)
Query Neighborhood Hits	471	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN11_MOUSE
NC score	0.662245 (rank : 43)	θ value	3.15612e-45 (rank : 12)
Query Neighborhood Hits	471	Target Neighborhood Hits	227	Shared Neighborhood Hits	71
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.662234 (rank : 44)	θ value	3.15612e-45 (rank : 11)
Query Neighborhood Hits	471	Target Neighborhood Hits	227	Shared Neighborhood Hits	71
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTPRB_HUMAN
NC score	0.661191 (rank : 45)	θ value	1.08474e-45 (rank : 8)
Query Neighborhood Hits	471	Target Neighborhood Hits	242	Shared Neighborhood Hits	72
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRK_HUMAN
NC score	0.657277 (rank : 46)	θ value	1.19932e-44 (rank : 14)
Query Neighborhood Hits	471	Target Neighborhood Hits	228	Shared Neighborhood Hits	66
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
NC score	0.655975 (rank : 47)	θ value	1.08474e-45 (rank : 9)
Query Neighborhood Hits	471	Target Neighborhood Hits	223	Shared Neighborhood Hits	66
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRT_HUMAN
NC score	0.652542 (rank : 48)	θ value	4.55743e-44 (rank : 16)
Query Neighborhood Hits	471	Target Neighborhood Hits	217	Shared Neighborhood Hits	67
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.652528 (rank : 49)	θ value	4.55743e-44 (rank : 17)
Query Neighborhood Hits	471	Target Neighborhood Hits	219	Shared Neighborhood Hits	66
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
NC score	0.643874 (rank : 50)	θ value	3.61944e-33 (rank : 60)
Query Neighborhood Hits	471	Target Neighborhood Hits	237	Shared Neighborhood Hits	69
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_MOUSE
NC score	0.641749 (rank : 51)	θ value	4.71619e-41 (rank : 31)
Query Neighborhood Hits	471	Target Neighborhood Hits	238	Shared Neighborhood Hits	66
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.640329 (rank : 52)	θ value	2.76489e-41 (rank : 29)
Query Neighborhood Hits	471	Target Neighborhood Hits	244	Shared Neighborhood Hits	66
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRZ_HUMAN
NC score	0.634055 (rank : 53)	θ value	3.27365e-34 (rank : 56)
Query Neighborhood Hits	471	Target Neighborhood Hits	255	Shared Neighborhood Hits	85
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_HUMAN
NC score	0.630531 (rank : 54)	θ value	5.0505e-35 (rank : 52)
Query Neighborhood Hits	471	Target Neighborhood Hits	231	Shared Neighborhood Hits	70
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
NC score	0.628537 (rank : 55)	θ value	7.29293e-34 (rank : 57)
Query Neighborhood Hits	471	Target Neighborhood Hits	260	Shared Neighborhood Hits	75
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTN23_MOUSE
NC score	0.620752 (rank : 56)	θ value	8.3442e-30 (rank : 69)
Query Neighborhood Hits	471	Target Neighborhood Hits	726	Shared Neighborhood Hits	92
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN23_HUMAN
NC score	0.619227 (rank : 57)	θ value	3.3877e-31 (rank : 66)
Query Neighborhood Hits	471	Target Neighborhood Hits	646	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRS_HUMAN
NC score	0.510266 (rank : 58)	θ value	1.41672e-45 (rank : 10)
Query Neighborhood Hits	471	Target Neighborhood Hits	472	Shared Neighborhood Hits	72
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRD_HUMAN
NC score	0.500767 (rank : 59)	θ value	9.18288e-45 (rank : 13)
Query Neighborhood Hits	471	Target Neighborhood Hits	485	Shared Neighborhood Hits	74
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.498528 (rank : 60)	θ value	4.86918e-46 (rank : 6)
Query Neighborhood Hits	471	Target Neighborhood Hits	489	Shared Neighborhood Hits	72
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

SYJ2B_HUMAN
NC score	0.492479 (rank : 61)	θ value	2.52405e-10 (rank : 141)
Query Neighborhood Hits	471	Target Neighborhood Hits	162	Shared Neighborhood Hits	154
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

PTPRD_MOUSE
NC score	0.492290 (rank : 62)	θ value	2.50074e-42 (rank : 25)
Query Neighborhood Hits	471	Target Neighborhood Hits	491	Shared Neighborhood Hits	74
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

MPDZ_MOUSE
NC score	0.491549 (rank : 63)	θ value	2.26708e-35 (rank : 51)
Query Neighborhood Hits	471	Target Neighborhood Hits	298	Shared Neighborhood Hits	197
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MPDZ_HUMAN
NC score	0.489947 (rank : 64)	θ value	8.06329e-33 (rank : 61)
Query Neighborhood Hits	471	Target Neighborhood Hits	261	Shared Neighborhood Hits	195
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

E41LA_HUMAN
NC score	0.489529 (rank : 65)	θ value	2.27234e-27 (rank : 75)
Query Neighborhood Hits	471	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.488978 (rank : 66)	θ value	8.63488e-27 (rank : 76)
Query Neighborhood Hits	471	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

INADL_MOUSE
NC score	0.484210 (rank : 67)	θ value	1.92365e-26 (rank : 78)
Query Neighborhood Hits	471	Target Neighborhood Hits	290	Shared Neighborhood Hits	200
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

INADL_HUMAN
NC score	0.481544 (rank : 68)	θ value	4.58923e-20 (rank : 94)
Query Neighborhood Hits	471	Target Neighborhood Hits	260	Shared Neighborhood Hits	196
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

E41LB_MOUSE
NC score	0.474093 (rank : 69)	θ value	9.24701e-21 (rank : 89)
Query Neighborhood Hits	471	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41L5_HUMAN
NC score	0.473544 (rank : 70)	θ value	5.99374e-20 (rank : 96)
Query Neighborhood Hits	471	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

FRMD5_MOUSE
NC score	0.473298 (rank : 71)	θ value	2.35696e-16 (rank : 114)
Query Neighborhood Hits	471	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L3_HUMAN
NC score	0.472655 (rank : 72)	θ value	2.12685e-25 (rank : 82)
Query Neighborhood Hits	471	Target Neighborhood Hits	113	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

FRMD6_MOUSE
NC score	0.472460 (rank : 73)	θ value	8.91499e-32 (rank : 62)
Query Neighborhood Hits	471	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

E41L1_MOUSE
NC score	0.472332 (rank : 74)	θ value	4.28545e-26 (rank : 80)
Query Neighborhood Hits	471	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_HUMAN
NC score	0.472047 (rank : 75)	θ value	4.28545e-26 (rank : 79)
Query Neighborhood Hits	471	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

FRMD5_HUMAN
NC score	0.471713 (rank : 76)	θ value	2.60593e-15 (rank : 118)
Query Neighborhood Hits	471	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L1_HUMAN
NC score	0.470713 (rank : 77)	θ value	1.92365e-26 (rank : 77)
Query Neighborhood Hits	471	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

FRMD1_HUMAN
NC score	0.469793 (rank : 78)	θ value	4.14116e-29 (rank : 72)
Query Neighborhood Hits	471	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

41_MOUSE
NC score	0.468829 (rank : 79)	θ value	8.93572e-24 (rank : 85)
Query Neighborhood Hits	471	Target Neighborhood Hits	184	Shared Neighborhood Hits	62
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41LB_HUMAN
NC score	0.468190 (rank : 80)	θ value	5.07402e-19 (rank : 103)
Query Neighborhood Hits	471	Target Neighborhood Hits	79	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

FRMD6_HUMAN
NC score	0.467709 (rank : 81)	θ value	4.89182e-30 (rank : 68)
Query Neighborhood Hits	471	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

E41L2_HUMAN
NC score	0.465765 (rank : 82)	θ value	4.28545e-26 (rank : 81)
Query Neighborhood Hits	471	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L3_MOUSE
NC score	0.465209 (rank : 83)	θ value	8.08199e-25 (rank : 83)
Query Neighborhood Hits	471	Target Neighborhood Hits	250	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

PAR3L_HUMAN
NC score	0.460682 (rank : 84)	θ value	6.85773e-16 (rank : 117)
Query Neighborhood Hits	471	Target Neighborhood Hits	297	Shared Neighborhood Hits	165
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PARD3_HUMAN
NC score	0.457412 (rank : 85)	θ value	8.65492e-19 (rank : 105)
Query Neighborhood Hits	471	Target Neighborhood Hits	312	Shared Neighborhood Hits	186
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

LIN7B_HUMAN
NC score	0.456951 (rank : 86)	θ value	1.33837e-11 (rank : 130)
Query Neighborhood Hits	471	Target Neighborhood Hits	200	Shared Neighborhood Hits	181
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7C_HUMAN
NC score	0.456764 (rank : 87)	θ value	3.89403e-11 (rank : 135)
Query Neighborhood Hits	471	Target Neighborhood Hits	198	Shared Neighborhood Hits	181
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.456764 (rank : 88)	θ value	3.89403e-11 (rank : 136)
Query Neighborhood Hits	471	Target Neighborhood Hits	198	Shared Neighborhood Hits	181
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

PARD3_MOUSE
NC score	0.456150 (rank : 89)	θ value	8.65492e-19 (rank : 106)
Query Neighborhood Hits	471	Target Neighborhood Hits	290	Shared Neighborhood Hits	185
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

LIN7B_MOUSE
NC score	0.455954 (rank : 90)	θ value	2.98157e-11 (rank : 133)
Query Neighborhood Hits	471	Target Neighborhood Hits	200	Shared Neighborhood Hits	181
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7A_HUMAN
NC score	0.452310 (rank : 91)	θ value	5.08577e-11 (rank : 137)
Query Neighborhood Hits	471	Target Neighborhood Hits	193	Shared Neighborhood Hits	178
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.452288 (rank : 92)	θ value	5.08577e-11 (rank : 138)
Query Neighborhood Hits	471	Target Neighborhood Hits	193	Shared Neighborhood Hits	178
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

E41L2_MOUSE
NC score	0.451819 (rank : 93)	θ value	1.05554e-24 (rank : 84)
Query Neighborhood Hits	471	Target Neighborhood Hits	459	Shared Neighborhood Hits	84
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MERL_HUMAN
NC score	0.449567 (rank : 94)	θ value	2.12192e-33 (rank : 58)
Query Neighborhood Hits	471	Target Neighborhood Hits	532	Shared Neighborhood Hits	84
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
NC score	0.449176 (rank : 95)	θ value	2.12192e-33 (rank : 59)
Query Neighborhood Hits	471	Target Neighborhood Hits	524	Shared Neighborhood Hits	83
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

FRM4B_HUMAN
NC score	0.444170 (rank : 96)	θ value	2.13179e-17 (rank : 113)
Query Neighborhood Hits	471	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.443676 (rank : 97)	θ value	9.56915e-18 (rank : 111)
Query Neighborhood Hits	471	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_HUMAN
NC score	0.441566 (rank : 98)	θ value	1.13037e-18 (rank : 107)
Query Neighborhood Hits	471	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

PDZD2_HUMAN
NC score	0.441449 (rank : 99)	θ value	5.42112e-21 (rank : 88)
Query Neighborhood Hits	471	Target Neighborhood Hits	772	Shared Neighborhood Hits	214
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

FRM4A_MOUSE
NC score	0.441027 (rank : 100)	θ value	6.62687e-19 (rank : 104)
Query Neighborhood Hits	471	Target Neighborhood Hits	108	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

PDZD7_HUMAN
NC score	0.436383 (rank : 101)	θ value	6.87365e-08 (rank : 168)
Query Neighborhood Hits	471	Target Neighborhood Hits	181	Shared Neighborhood Hits	166
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

DLG4_MOUSE
NC score	0.434932 (rank : 102)	θ value	1.74391e-19 (rank : 99)
Query Neighborhood Hits	471	Target Neighborhood Hits	282	Shared Neighborhood Hits	183
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.434222 (rank : 103)	θ value	2.27762e-19 (rank : 100)
Query Neighborhood Hits	471	Target Neighborhood Hits	286	Shared Neighborhood Hits	181
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

IL16_HUMAN
NC score	0.433146 (rank : 104)	θ value	4.16044e-13 (rank : 123)
Query Neighborhood Hits	471	Target Neighborhood Hits	207	Shared Neighborhood Hits	148
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

DLG2_MOUSE
NC score	0.432488 (rank : 105)	θ value	7.56453e-23 (rank : 86)
Query Neighborhood Hits	471	Target Neighborhood Hits	271	Shared Neighborhood Hits	179
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

USH1C_HUMAN
NC score	0.431996 (rank : 106)	θ value	3.08544e-08 (rank : 164)
Query Neighborhood Hits	471	Target Neighborhood Hits	327	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

DLG2_HUMAN
NC score	0.431167 (rank : 107)	θ value	3.17815e-21 (rank : 87)
Query Neighborhood Hits	471	Target Neighborhood Hits	279	Shared Neighborhood Hits	180
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

MYLIP_MOUSE
NC score	0.430246 (rank : 108)	θ value	8.11959e-09 (rank : 152)
Query Neighborhood Hits	471	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

DLG3_MOUSE
NC score	0.428286 (rank : 109)	θ value	1.33526e-19 (rank : 98)
Query Neighborhood Hits	471	Target Neighborhood Hits	274	Shared Neighborhood Hits	181
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

LNX2_MOUSE
NC score	0.428112 (rank : 110)	θ value	5.25075e-16 (rank : 116)
Query Neighborhood Hits	471	Target Neighborhood Hits	407	Shared Neighborhood Hits	179
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

DLG1_HUMAN
NC score	0.427539 (rank : 111)	θ value	1.2077e-20 (rank : 90)
Query Neighborhood Hits	471	Target Neighborhood Hits	290	Shared Neighborhood Hits	182
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

GRIP2_HUMAN
NC score	0.426768 (rank : 112)	θ value	3.52202e-12 (rank : 127)
Query Neighborhood Hits	471	Target Neighborhood Hits	256	Shared Neighborhood Hits	191
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

DLG3_HUMAN
NC score	0.426606 (rank : 113)	θ value	1.33526e-19 (rank : 97)
Query Neighborhood Hits	471	Target Neighborhood Hits	269	Shared Neighborhood Hits	181
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_MOUSE
NC score	0.425910 (rank : 114)	θ value	3.51386e-20 (rank : 91)
Query Neighborhood Hits	471	Target Neighborhood Hits	285	Shared Neighborhood Hits	173
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

LNX2_HUMAN
NC score	0.422360 (rank : 115)	θ value	1.13037e-18 (rank : 109)
Query Neighborhood Hits	471	Target Neighborhood Hits	389	Shared Neighborhood Hits	177
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

EZRI_HUMAN
NC score	0.422357 (rank : 116)	θ value	2.05525e-28 (rank : 73)
Query Neighborhood Hits	471	Target Neighborhood Hits	663	Shared Neighborhood Hits	87
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

WHRN_MOUSE
NC score	0.422000 (rank : 117)	θ value	2.79066e-09 (rank : 149)
Query Neighborhood Hits	471	Target Neighborhood Hits	412	Shared Neighborhood Hits	193
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

MAGI1_MOUSE
NC score	0.421729 (rank : 118)	θ value	7.32683e-18 (rank : 110)
Query Neighborhood Hits	471	Target Neighborhood Hits	403	Shared Neighborhood Hits	213
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

EZRI_MOUSE
NC score	0.421195 (rank : 119)	θ value	2.68423e-28 (rank : 74)
Query Neighborhood Hits	471	Target Neighborhood Hits	693	Shared Neighborhood Hits	86
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

MYLIP_HUMAN
NC score	0.420818 (rank : 120)	θ value	2.36244e-08 (rank : 159)
Query Neighborhood Hits	471	Target Neighborhood Hits	162	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

IL16_MOUSE
NC score	0.420379 (rank : 121)	θ value	4.16044e-13 (rank : 124)
Query Neighborhood Hits	471	Target Neighborhood Hits	189	Shared Neighborhood Hits	139
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZ11_MOUSE
NC score	0.420329 (rank : 122)	θ value	4.45536e-07 (rank : 176)
Query Neighborhood Hits	471	Target Neighborhood Hits	154	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

WHRN_HUMAN
NC score	0.420058 (rank : 123)	θ value	1.06045e-08 (rank : 154)
Query Neighborhood Hits	471	Target Neighborhood Hits	325	Shared Neighborhood Hits	190
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

PDZ11_HUMAN
NC score	0.419687 (rank : 124)	θ value	9.92553e-07 (rank : 183)
Query Neighborhood Hits	471	Target Neighborhood Hits	160	Shared Neighborhood Hits	146
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

MAGI1_HUMAN
NC score	0.419595 (rank : 125)	θ value	4.58923e-20 (rank : 95)
Query Neighborhood Hits	471	Target Neighborhood Hits	388	Shared Neighborhood Hits	211
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

GRIP1_MOUSE
NC score	0.417546 (rank : 126)	θ value	9.59137e-10 (rank : 145)
Query Neighborhood Hits	471	Target Neighborhood Hits	241	Shared Neighborhood Hits	191
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_HUMAN
NC score	0.417482 (rank : 127)	θ value	7.34386e-10 (rank : 143)
Query Neighborhood Hits	471	Target Neighborhood Hits	231	Shared Neighborhood Hits	192
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

RADI_HUMAN
NC score	0.415212 (rank : 128)	θ value	1.52067e-31 (rank : 63)
Query Neighborhood Hits	471	Target Neighborhood Hits	741	Shared Neighborhood Hits	86
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

LNX1_MOUSE
NC score	0.414150 (rank : 129)	θ value	2.43908e-13 (rank : 122)
Query Neighborhood Hits	471	Target Neighborhood Hits	377	Shared Neighborhood Hits	179
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAGI2_MOUSE
NC score	0.412979 (rank : 130)	θ value	3.51386e-20 (rank : 93)
Query Neighborhood Hits	471	Target Neighborhood Hits	370	Shared Neighborhood Hits	195
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

RADI_MOUSE
NC score	0.412957 (rank : 131)	θ value	1.52067e-31 (rank : 64)
Query Neighborhood Hits	471	Target Neighborhood Hits	773	Shared Neighborhood Hits	87
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MAGI2_HUMAN
NC score	0.410734 (rank : 132)	θ value	2.97466e-19 (rank : 102)
Query Neighborhood Hits	471	Target Neighborhood Hits	373	Shared Neighborhood Hits	190
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

LNX1_HUMAN
NC score	0.407903 (rank : 133)	θ value	1.42992e-13 (rank : 120)
Query Neighborhood Hits	471	Target Neighborhood Hits	379	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

USH1C_MOUSE
NC score	0.405147 (rank : 134)	θ value	3.08544e-08 (rank : 165)
Query Neighborhood Hits	471	Target Neighborhood Hits	557	Shared Neighborhood Hits	208
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PDZD1_MOUSE
NC score	0.405021 (rank : 135)	θ value	1.74796e-11 (rank : 131)
Query Neighborhood Hits	471	Target Neighborhood Hits	191	Shared Neighborhood Hits	155
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD1_HUMAN
NC score	0.398380 (rank : 136)	θ value	2.13673e-09 (rank : 147)
Query Neighborhood Hits	471	Target Neighborhood Hits	190	Shared Neighborhood Hits	155
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHERF_MOUSE
NC score	0.397595 (rank : 137)	θ value	6.00763e-12 (rank : 128)
Query Neighborhood Hits	471	Target Neighborhood Hits	195	Shared Neighborhood Hits	158
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

GOPC_MOUSE
NC score	0.391681 (rank : 138)	θ value	4.45536e-07 (rank : 175)
Query Neighborhood Hits	471	Target Neighborhood Hits	323	Shared Neighborhood Hits	174
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

MOES_HUMAN
NC score	0.389255 (rank : 139)	θ value	2.42779e-29 (rank : 71)
Query Neighborhood Hits	471	Target Neighborhood Hits	892	Shared Neighborhood Hits	85
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FARP1_HUMAN
NC score	0.387294 (rank : 140)	θ value	5.25075e-16 (rank : 115)
Query Neighborhood Hits	471	Target Neighborhood Hits	241	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

NHRF2_HUMAN
NC score	0.386917 (rank : 141)	θ value	1.25267e-09 (rank : 146)
Query Neighborhood Hits	471	Target Neighborhood Hits	197	Shared Neighborhood Hits	165
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

GOPC_HUMAN
NC score	0.386268 (rank : 142)	θ value	4.45536e-07 (rank : 174)
Query Neighborhood Hits	471	Target Neighborhood Hits	377	Shared Neighborhood Hits	176
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

MOES_MOUSE
NC score	0.385172 (rank : 143)	θ value	1.85889e-29 (rank : 70)
Query Neighborhood Hits	471	Target Neighborhood Hits	923	Shared Neighborhood Hits	90
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NHERF_HUMAN
NC score	0.383679 (rank : 144)	θ value	4.30538e-10 (rank : 142)
Query Neighborhood Hits	471	Target Neighborhood Hits	190	Shared Neighborhood Hits	156
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

ZO3_MOUSE
NC score	0.383382 (rank : 145)	θ value	7.34386e-10 (rank : 144)
Query Neighborhood Hits	471	Target Neighborhood Hits	224	Shared Neighborhood Hits	175
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

TX1B3_HUMAN
NC score	0.382428 (rank : 146)	θ value	0.00102713 (rank : 214)
Query Neighborhood Hits	471	Target Neighborhood Hits	161	Shared Neighborhood Hits	148
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
NC score	0.379620 (rank : 147)	θ value	0.00102713 (rank : 215)
Query Neighborhood Hits	471	Target Neighborhood Hits	158	Shared Neighborhood Hits	145
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

ZO3_HUMAN
NC score	0.378613 (rank : 148)	θ value	4.0297e-08 (rank : 167)
Query Neighborhood Hits	471	Target Neighborhood Hits	219	Shared Neighborhood Hits	170
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SNTG2_HUMAN
NC score	0.377306 (rank : 149)	θ value	4.45536e-07 (rank : 177)
Query Neighborhood Hits	471	Target Neighborhood Hits	191	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

NHRF2_MOUSE
NC score	0.376939 (rank : 150)	θ value	3.08544e-08 (rank : 163)
Query Neighborhood Hits	471	Target Neighborhood Hits	194	Shared Neighborhood Hits	165
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

FARP2_HUMAN
NC score	0.376143 (rank : 151)	θ value	2.13179e-17 (rank : 112)
Query Neighborhood Hits	471	Target Neighborhood Hits	240	Shared Neighborhood Hits	59
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.374707 (rank : 152)	θ value	3.51386e-20 (rank : 92)
Query Neighborhood Hits	471	Target Neighborhood Hits	209	Shared Neighborhood Hits	56
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PDZD3_HUMAN
NC score	0.370289 (rank : 153)	θ value	4.76016e-09 (rank : 151)
Query Neighborhood Hits	471	Target Neighborhood Hits	180	Shared Neighborhood Hits	157
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

ZO1_MOUSE
NC score	0.364484 (rank : 154)	θ value	1.02475e-11 (rank : 129)
Query Neighborhood Hits	471	Target Neighborhood Hits	453	Shared Neighborhood Hits	178
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
NC score	0.363964 (rank : 155)	θ value	1.86753e-13 (rank : 121)
Query Neighborhood Hits	471	Target Neighborhood Hits	289	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
NC score	0.362794 (rank : 156)	θ value	1.09485e-13 (rank : 119)
Query Neighborhood Hits	471	Target Neighborhood Hits	296	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO1_HUMAN
NC score	0.361478 (rank : 157)	θ value	2.28291e-11 (rank : 132)
Query Neighborhood Hits	471	Target Neighborhood Hits	474	Shared Neighborhood Hits	178
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SNTG2_MOUSE
NC score	0.360332 (rank : 158)	θ value	4.45536e-07 (rank : 178)
Query Neighborhood Hits	471	Target Neighborhood Hits	176	Shared Neighborhood Hits	165
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTB2_MOUSE
NC score	0.359049 (rank : 159)	θ value	2.88788e-06 (rank : 189)
Query Neighborhood Hits	471	Target Neighborhood Hits	181	Shared Neighborhood Hits	159
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_HUMAN
NC score	0.357839 (rank : 160)	θ value	8.40245e-06 (rank : 192)
Query Neighborhood Hits	471	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

K1849_HUMAN
NC score	0.354876 (rank : 161)	θ value	2.69671e-12 (rank : 126)
Query Neighborhood Hits	471	Target Neighborhood Hits	220	Shared Neighborhood Hits	141
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SNTG1_MOUSE
NC score	0.351441 (rank : 162)	θ value	7.59969e-07 (rank : 182)
Query Neighborhood Hits	471	Target Neighborhood Hits	179	Shared Neighborhood Hits	169
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_HUMAN
NC score	0.350512 (rank : 163)	θ value	2.88788e-06 (rank : 190)
Query Neighborhood Hits	471	Target Neighborhood Hits	181	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PZRN4_HUMAN
NC score	0.347937 (rank : 164)	θ value	1.80886e-08 (rank : 157)
Query Neighborhood Hits	471	Target Neighborhood Hits	438	Shared Neighborhood Hits	152
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

SNTA1_HUMAN
NC score	0.347774 (rank : 165)	θ value	0.000158464 (rank : 209)
Query Neighborhood Hits	471	Target Neighborhood Hits	186	Shared Neighborhood Hits	163
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

K1849_MOUSE
NC score	0.345991 (rank : 166)	θ value	7.09661e-13 (rank : 125)
Query Neighborhood Hits	471	Target Neighborhood Hits	335	Shared Neighborhood Hits	153
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

PDZD3_MOUSE
NC score	0.345515 (rank : 167)	θ value	0.000158464 (rank : 208)
Query Neighborhood Hits	471	Target Neighborhood Hits	171	Shared Neighborhood Hits	154
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SNTA1_MOUSE
NC score	0.341764 (rank : 168)	θ value	0.000158464 (rank : 210)
Query Neighborhood Hits	471	Target Neighborhood Hits	170	Shared Neighborhood Hits	157
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

PZRN3_HUMAN
NC score	0.340049 (rank : 169)	θ value	1.80886e-08 (rank : 156)
Query Neighborhood Hits	471	Target Neighborhood Hits	461	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
NC score	0.339567 (rank : 170)	θ value	8.97725e-08 (rank : 169)
Query Neighborhood Hits	471	Target Neighborhood Hits	447	Shared Neighborhood Hits	155
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SNTB1_HUMAN
NC score	0.336252 (rank : 171)	θ value	7.1131e-05 (rank : 203)
Query Neighborhood Hits	471	Target Neighborhood Hits	157	Shared Neighborhood Hits	148
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.335356 (rank : 172)	θ value	7.1131e-05 (rank : 204)
Query Neighborhood Hits	471	Target Neighborhood Hits	160	Shared Neighborhood Hits	146
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

AFAD_HUMAN
NC score	0.312297 (rank : 173)	θ value	3.64472e-09 (rank : 150)
Query Neighborhood Hits	471	Target Neighborhood Hits	689	Shared Neighborhood Hits	162
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

DVL3_HUMAN
NC score	0.305272 (rank : 174)	θ value	3.08544e-08 (rank : 162)
Query Neighborhood Hits	471	Target Neighborhood Hits	194	Shared Neighborhood Hits	118
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
NC score	0.304628 (rank : 175)	θ value	1.17247e-07 (rank : 170)
Query Neighborhood Hits	471	Target Neighborhood Hits	198	Shared Neighborhood Hits	118
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

NEB1_HUMAN
NC score	0.303687 (rank : 176)	θ value	2.98157e-11 (rank : 134)
Query Neighborhood Hits	471	Target Neighborhood Hits	829	Shared Neighborhood Hits	182
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

DVL1_HUMAN
NC score	0.302124 (rank : 177)	θ value	3.41135e-07 (rank : 173)
Query Neighborhood Hits	471	Target Neighborhood Hits	158	Shared Neighborhood Hits	119
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

LAP4_HUMAN
NC score	0.301024 (rank : 178)	θ value	1.13037e-18 (rank : 108)
Query Neighborhood Hits	471	Target Neighborhood Hits	608	Shared Neighborhood Hits	197
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

DVL1_MOUSE
NC score	0.300995 (rank : 179)	θ value	2.36244e-08 (rank : 158)
Query Neighborhood Hits	471	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

LAP4_MOUSE
NC score	0.300887 (rank : 180)	θ value	2.27762e-19 (rank : 101)
Query Neighborhood Hits	471	Target Neighborhood Hits	590	Shared Neighborhood Hits	201
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

DVL2_HUMAN
NC score	0.293743 (rank : 181)	θ value	2.79066e-09 (rank : 148)
Query Neighborhood Hits	471	Target Neighborhood Hits	223	Shared Neighborhood Hits	120
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
NC score	0.293078 (rank : 182)	θ value	1.06045e-08 (rank : 153)
Query Neighborhood Hits	471	Target Neighborhood Hits	233	Shared Neighborhood Hits	119
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL1L_HUMAN
NC score	0.292435 (rank : 183)	θ value	5.81887e-07 (rank : 181)
Query Neighborhood Hits	471	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

NEB2_HUMAN
NC score	0.287975 (rank : 184)	θ value	1.47974e-10 (rank : 139)
Query Neighborhood Hits	471	Target Neighborhood Hits	883	Shared Neighborhood Hits	155
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
NC score	0.283304 (rank : 185)	θ value	1.47974e-10 (rank : 140)
Query Neighborhood Hits	471	Target Neighborhood Hits	889	Shared Neighborhood Hits	159
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDZK4_MOUSE
NC score	0.273646 (rank : 186)	θ value	4.1701e-05 (rank : 200)
Query Neighborhood Hits	471	Target Neighborhood Hits	165	Shared Neighborhood Hits	125
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_HUMAN
NC score	0.272856 (rank : 187)	θ value	0.000121331 (rank : 206)
Query Neighborhood Hits	471	Target Neighborhood Hits	165	Shared Neighborhood Hits	116
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

STXB4_HUMAN
NC score	0.272466 (rank : 188)	θ value	4.45536e-07 (rank : 179)
Query Neighborhood Hits	471	Target Neighborhood Hits	616	Shared Neighborhood Hits	134
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

MPP4_HUMAN
NC score	0.270899 (rank : 189)	θ value	4.1701e-05 (rank : 199)
Query Neighborhood Hits	471	Target Neighborhood Hits	205	Shared Neighborhood Hits	138
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

DLG5_HUMAN
NC score	0.268205 (rank : 190)	θ value	5.81887e-07 (rank : 180)
Query Neighborhood Hits	471	Target Neighborhood Hits	1088	Shared Neighborhood Hits	206
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GRASP_HUMAN
NC score	0.266861 (rank : 191)	θ value	4.92598e-06 (rank : 191)
Query Neighborhood Hits	471	Target Neighborhood Hits	147	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.263045 (rank : 192)	θ value	1.43324e-05 (rank : 194)
Query Neighborhood Hits	471	Target Neighborhood Hits	131	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

STXB4_MOUSE
NC score	0.262220 (rank : 193)	θ value	1.29631e-06 (rank : 185)
Query Neighborhood Hits	471	Target Neighborhood Hits	629	Shared Neighborhood Hits	121
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PICK1_MOUSE
NC score	0.257444 (rank : 194)	θ value	0.00390308 (rank : 227)
Query Neighborhood Hits	471	Target Neighborhood Hits	131	Shared Neighborhood Hits	121
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_HUMAN
NC score	0.257039 (rank : 195)	θ value	0.00509761 (rank : 229)
Query Neighborhood Hits	471	Target Neighborhood Hits	132	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

APBA1_HUMAN
NC score	0.254331 (rank : 196)	θ value	0.00298849 (rank : 221)
Query Neighborhood Hits	471	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

MPP5_HUMAN
NC score	0.253683 (rank : 197)	θ value	0.00298849 (rank : 222)
Query Neighborhood Hits	471	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.253015 (rank : 198)	θ value	0.00298849 (rank : 223)
Query Neighborhood Hits	471	Target Neighborhood Hits	226	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

APBA2_MOUSE
NC score	0.247372 (rank : 199)	θ value	0.000786445 (rank : 212)
Query Neighborhood Hits	471	Target Neighborhood Hits	219	Shared Neighborhood Hits	151
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.246849 (rank : 200)	θ value	0.000786445 (rank : 211)
Query Neighborhood Hits	471	Target Neighborhood Hits	220	Shared Neighborhood Hits	153
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

MPP4_MOUSE
NC score	0.245036 (rank : 201)	θ value	0.000158464 (rank : 207)
Query Neighborhood Hits	471	Target Neighborhood Hits	188	Shared Neighborhood Hits	120
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP3_MOUSE
NC score	0.244712 (rank : 202)	θ value	0.0193708 (rank : 242)
Query Neighborhood Hits	471	Target Neighborhood Hits	165	Shared Neighborhood Hits	134
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

PAR6G_MOUSE
NC score	0.243609 (rank : 203)	θ value	0.00390308 (rank : 226)
Query Neighborhood Hits	471	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PAR6G_HUMAN
NC score	0.243468 (rank : 204)	θ value	0.00390308 (rank : 225)
Query Neighborhood Hits	471	Target Neighborhood Hits	159	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

MPP3_HUMAN
NC score	0.242608 (rank : 205)	θ value	0.0193708 (rank : 241)
Query Neighborhood Hits	471	Target Neighborhood Hits	171	Shared Neighborhood Hits	135
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

TLN1_HUMAN
NC score	0.242026 (rank : 206)	θ value	4.0297e-08 (rank : 166)
Query Neighborhood Hits	471	Target Neighborhood Hits	218	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.241347 (rank : 207)	θ value	1.69304e-06 (rank : 186)
Query Neighborhood Hits	471	Target Neighborhood Hits	149	Shared Neighborhood Hits	55
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN1_MOUSE
NC score	0.240640 (rank : 208)	θ value	2.36244e-08 (rank : 161)
Query Neighborhood Hits	471	Target Neighborhood Hits	213	Shared Neighborhood Hits	57
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

APBA3_HUMAN
NC score	0.238995 (rank : 209)	θ value	0.0113563 (rank : 233)
Query Neighborhood Hits	471	Target Neighborhood Hits	201	Shared Neighborhood Hits	144
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PAR6B_HUMAN
NC score	0.238994 (rank : 210)	θ value	0.0113563 (rank : 236)
Query Neighborhood Hits	471	Target Neighborhood Hits	126	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
NC score	0.238350 (rank : 211)	θ value	0.0148317 (rank : 239)
Query Neighborhood Hits	471	Target Neighborhood Hits	128	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

TLN2_HUMAN
NC score	0.237869 (rank : 212)	θ value	9.92553e-07 (rank : 184)
Query Neighborhood Hits	471	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

RPGF6_HUMAN
NC score	0.234078 (rank : 213)	θ value	2.44474e-05 (rank : 197)
Query Neighborhood Hits	471	Target Neighborhood Hits	266	Shared Neighborhood Hits	157
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PDLI2_HUMAN
NC score	0.230281 (rank : 214)	θ value	0.00298849 (rank : 224)
Query Neighborhood Hits	471	Target Neighborhood Hits	245	Shared Neighborhood Hits	123
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

SDCB1_MOUSE
NC score	0.229830 (rank : 215)	θ value	0.0961366 (rank : 262)
Query Neighborhood Hits	471	Target Neighborhood Hits	144	Shared Neighborhood Hits	131
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SDCB1_HUMAN
NC score	0.229663 (rank : 216)	θ value	0.0252991 (rank : 245)
Query Neighborhood Hits	471	Target Neighborhood Hits	150	Shared Neighborhood Hits	139
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

PAR6A_MOUSE
NC score	0.229125 (rank : 217)	θ value	0.0148317 (rank : 238)
Query Neighborhood Hits	471	Target Neighborhood Hits	115	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

RHPN1_MOUSE
NC score	0.228388 (rank : 218)	θ value	0.0252991 (rank : 244)
Query Neighborhood Hits	471	Target Neighborhood Hits	154	Shared Neighborhood Hits	124
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

PAR6A_HUMAN
NC score	0.228097 (rank : 219)	θ value	0.0193708 (rank : 243)
Query Neighborhood Hits	471	Target Neighborhood Hits	119	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

APBA3_MOUSE
NC score	0.224323 (rank : 220)	θ value	0.0961366 (rank : 260)
Query Neighborhood Hits	471	Target Neighborhood Hits	174	Shared Neighborhood Hits	137
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

DUS23_MOUSE
NC score	0.224240 (rank : 221)	θ value	1.38821 (rank : 322)
Query Neighborhood Hits	471	Target Neighborhood Hits	94	Shared Neighborhood Hits	57
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

PSCBP_MOUSE
NC score	0.218559 (rank : 222)	θ value	0.0961366 (rank : 261)
Query Neighborhood Hits	471	Target Neighborhood Hits	118	Shared Neighborhood Hits	107
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

DUS23_HUMAN
NC score	0.217410 (rank : 223)	θ value	0.62314 (rank : 299)
Query Neighborhood Hits	471	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

NOS1_HUMAN
NC score	0.215924 (rank : 224)	θ value	2.36244e-08 (rank : 160)
Query Neighborhood Hits	471	Target Neighborhood Hits	218	Shared Neighborhood Hits	137
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PDLI2_MOUSE
NC score	0.212419 (rank : 225)	θ value	0.0330416 (rank : 247)
Query Neighborhood Hits	471	Target Neighborhood Hits	220	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

RHPN1_HUMAN
NC score	0.211930 (rank : 226)	θ value	0.813845 (rank : 306)
Query Neighborhood Hits	471	Target Neighborhood Hits	158	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

EM55_HUMAN
NC score	0.209379 (rank : 227)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	471	Target Neighborhood Hits	228	Shared Neighborhood Hits	129
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.207931 (rank : 228)	θ value	6.88961 (rank : 421)
Query Neighborhood Hits	471	Target Neighborhood Hits	221	Shared Neighborhood Hits	127
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

ARHGB_HUMAN
NC score	0.204577 (rank : 229)	θ value	0.00134147 (rank : 216)
Query Neighborhood Hits	471	Target Neighborhood Hits	375	Shared Neighborhood Hits	167
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

PSCBP_HUMAN
NC score	0.203856 (rank : 230)	θ value	0.279714 (rank : 283)
Query Neighborhood Hits	471	Target Neighborhood Hits	123	Shared Neighborhood Hits	110
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

RPGF2_HUMAN
NC score	0.197914 (rank : 231)	θ value	0.00134147 (rank : 218)
Query Neighborhood Hits	471	Target Neighborhood Hits	242	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

ARHGC_MOUSE
NC score	0.196827 (rank : 232)	θ value	2.21117e-06 (rank : 187)
Query Neighborhood Hits	471	Target Neighborhood Hits	344	Shared Neighborhood Hits	149
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_HUMAN
NC score	0.196806 (rank : 233)	θ value	2.88788e-06 (rank : 188)
Query Neighborhood Hits	471	Target Neighborhood Hits	351	Shared Neighborhood Hits	146
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SDCB2_HUMAN
NC score	0.196088 (rank : 234)	θ value	0.0330416 (rank : 250)
Query Neighborhood Hits	471	Target Neighborhood Hits	121	Shared Neighborhood Hits	110
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB2_MOUSE
NC score	0.195490 (rank : 235)	θ value	0.365318 (rank : 290)
Query Neighborhood Hits	471	Target Neighborhood Hits	118	Shared Neighborhood Hits	111
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

NOS1_MOUSE
NC score	0.192972 (rank : 236)	θ value	1.38499e-08 (rank : 155)
Query Neighborhood Hits	471	Target Neighborhood Hits	155	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

MPP2_HUMAN
NC score	0.190071 (rank : 237)	θ value	0.00134147 (rank : 217)
Query Neighborhood Hits	471	Target Neighborhood Hits	173	Shared Neighborhood Hits	92
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
NC score	0.190044 (rank : 238)	θ value	0.0113563 (rank : 235)
Query Neighborhood Hits	471	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

SYP2L_HUMAN
NC score	0.190039 (rank : 239)	θ value	0.47712 (rank : 296)
Query Neighborhood Hits	471	Target Neighborhood Hits	400	Shared Neighborhood Hits	118
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

MPP6_MOUSE
NC score	0.181558 (rank : 240)	θ value	6.88961 (rank : 426)
Query Neighborhood Hits	471	Target Neighborhood Hits	187	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP6_HUMAN
NC score	0.179242 (rank : 241)	θ value	6.88961 (rank : 425)
Query Neighborhood Hits	471	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

RGS12_HUMAN
NC score	0.175228 (rank : 242)	θ value	0.00228821 (rank : 220)
Query Neighborhood Hits	471	Target Neighborhood Hits	333	Shared Neighborhood Hits	137
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RIMS1_HUMAN
NC score	0.172937 (rank : 243)	θ value	1.43324e-05 (rank : 195)
Query Neighborhood Hits	471	Target Neighborhood Hits	437	Shared Neighborhood Hits	146
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYNP2_MOUSE
NC score	0.172147 (rank : 244)	θ value	0.0961366 (rank : 264)
Query Neighborhood Hits	471	Target Neighborhood Hits	252	Shared Neighborhood Hits	116
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

APXL_HUMAN
NC score	0.167418 (rank : 245)	θ value	0.00665767 (rank : 230)
Query Neighborhood Hits	471	Target Neighborhood Hits	553	Shared Neighborhood Hits	113
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

LRRC7_HUMAN
NC score	0.162433 (rank : 246)	θ value	1.09739e-05 (rank : 193)
Query Neighborhood Hits	471	Target Neighborhood Hits	423	Shared Neighborhood Hits	122
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.161235 (rank : 247)	θ value	2.44474e-05 (rank : 196)
Query Neighborhood Hits	471	Target Neighborhood Hits	416	Shared Neighborhood Hits	118
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

RIMS2_MOUSE
NC score	0.156842 (rank : 248)	θ value	2.61198e-07 (rank : 172)
Query Neighborhood Hits	471	Target Neighborhood Hits	376	Shared Neighborhood Hits	127
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS2_HUMAN
NC score	0.156254 (rank : 249)	θ value	1.99992e-07 (rank : 171)
Query Neighborhood Hits	471	Target Neighborhood Hits	342	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SHAN2_HUMAN
NC score	0.154445 (rank : 250)	θ value	6.88961 (rank : 434)
Query Neighborhood Hits	471	Target Neighborhood Hits	346	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

LAP2_HUMAN
NC score	0.153147 (rank : 251)	θ value	7.1131e-05 (rank : 202)
Query Neighborhood Hits	471	Target Neighborhood Hits	499	Shared Neighborhood Hits	116
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PDLI4_MOUSE
NC score	0.149773 (rank : 252)	θ value	0.0330416 (rank : 248)
Query Neighborhood Hits	471	Target Neighborhood Hits	233	Shared Neighborhood Hits	107
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI3_HUMAN
NC score	0.148354 (rank : 253)	θ value	5.27518 (rank : 398)
Query Neighborhood Hits	471	Target Neighborhood Hits	199	Shared Neighborhood Hits	103
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI4_HUMAN
NC score	0.146280 (rank : 254)	θ value	0.0736092 (rank : 259)
Query Neighborhood Hits	471	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

GIPC1_MOUSE
NC score	0.146115 (rank : 255)	θ value	0.163984 (rank : 270)
Query Neighborhood Hits	471	Target Neighborhood Hits	92	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

LAP2_MOUSE
NC score	0.145951 (rank : 256)	θ value	0.000121331 (rank : 205)
Query Neighborhood Hits	471	Target Neighborhood Hits	482	Shared Neighborhood Hits	115
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

GIPC1_HUMAN
NC score	0.140923 (rank : 257)	θ value	0.125558 (rank : 267)
Query Neighborhood Hits	471	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

SHAN2_MOUSE
NC score	0.138113 (rank : 258)	θ value	1.81305 (rank : 340)
Query Neighborhood Hits	471	Target Neighborhood Hits	446	Shared Neighborhood Hits	122
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SYP2L_MOUSE
NC score	0.137752 (rank : 259)	θ value	2.36792 (rank : 355)
Query Neighborhood Hits	471	Target Neighborhood Hits	289	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PDLI3_MOUSE
NC score	0.137102 (rank : 260)	θ value	6.88961 (rank : 430)
Query Neighborhood Hits	471	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

KGUA_MOUSE
NC score	0.134237 (rank : 261)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	471	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_HUMAN
NC score	0.133774 (rank : 262)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	471	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

SYNP2_HUMAN
NC score	0.131974 (rank : 263)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	471	Target Neighborhood Hits	323	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

PDLI1_MOUSE
NC score	0.131599 (rank : 264)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	471	Target Neighborhood Hits	213	Shared Neighborhood Hits	98
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_HUMAN
NC score	0.128243 (rank : 265)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	471	Target Neighborhood Hits	242	Shared Neighborhood Hits	98
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PCLO_MOUSE
NC score	0.125629 (rank : 266)	θ value	0.00102713 (rank : 213)
Query Neighborhood Hits	471	Target Neighborhood Hits	2275	Shared Neighborhood Hits	209
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

LDB3_MOUSE
NC score	0.122086 (rank : 267)	θ value	0.21417 (rank : 276)
Query Neighborhood Hits	471	Target Neighborhood Hits	510	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LDB3_HUMAN
NC score	0.120622 (rank : 268)	θ value	0.21417 (rank : 275)
Query Neighborhood Hits	471	Target Neighborhood Hits	497	Shared Neighborhood Hits	110
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

GIPC2_HUMAN
NC score	0.120253 (rank : 269)	θ value	0.365318 (rank : 286)
Query Neighborhood Hits	471	Target Neighborhood Hits	93	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

PDZD6_HUMAN
NC score	0.116133 (rank : 270)	θ value	1.81305 (rank : 339)
Query Neighborhood Hits	471	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

CC14B_MOUSE
NC score	0.115299 (rank : 271)	θ value	0.62314 (rank : 297)
Query Neighborhood Hits	471	Target Neighborhood Hits	103	Shared Neighborhood Hits	55
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PDLI5_MOUSE
NC score	0.114403 (rank : 272)	θ value	0.21417 (rank : 278)
Query Neighborhood Hits	471	Target Neighborhood Hits	287	Shared Neighborhood Hits	114
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_HUMAN
NC score	0.113744 (rank : 273)	θ value	0.0330416 (rank : 249)
Query Neighborhood Hits	471	Target Neighborhood Hits	322	Shared Neighborhood Hits	122
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

CC14B_HUMAN
NC score	0.112718 (rank : 274)	θ value	2.36792 (rank : 344)
Query Neighborhood Hits	471	Target Neighborhood Hits	114	Shared Neighborhood Hits	60
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14A_MOUSE
NC score	0.105314 (rank : 275)	θ value	0.813845 (rank : 303)
Query Neighborhood Hits	471	Target Neighborhood Hits	117	Shared Neighborhood Hits	58
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_HUMAN
NC score	0.104515 (rank : 276)	θ value	0.813845 (rank : 302)
Query Neighborhood Hits	471	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

FINC_HUMAN
NC score	0.101975 (rank : 277)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	471	Target Neighborhood Hits	302	Shared Neighborhood Hits	25
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.100602 (rank : 278)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	471	Target Neighborhood Hits	309	Shared Neighborhood Hits	24
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

PDLI7_HUMAN
NC score	0.100006 (rank : 279)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	471	Target Neighborhood Hits	547	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SHAN1_HUMAN
NC score	0.097958 (rank : 280)	θ value	2.36792 (rank : 354)
Query Neighborhood Hits	471	Target Neighborhood Hits	1041	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PDLI7_MOUSE
NC score	0.094337 (rank : 281)	θ value	0.47712 (rank : 295)
Query Neighborhood Hits	471	Target Neighborhood Hits	279	Shared Neighborhood Hits	96
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

FNDC3_HUMAN
NC score	0.091927 (rank : 282)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	471	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

CNKR2_MOUSE
NC score	0.090145 (rank : 283)	θ value	0.21417 (rank : 274)
Query Neighborhood Hits	471	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.090059 (rank : 284)	θ value	0.21417 (rank : 273)
Query Neighborhood Hits	471	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

TP4A1_HUMAN
NC score	0.089445 (rank : 285)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	471	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.089445 (rank : 286)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	471	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

FNDC3_MOUSE
NC score	0.085672 (rank : 287)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	471	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

GIPC3_HUMAN
NC score	0.085244 (rank : 288)	θ value	1.38821 (rank : 323)
Query Neighborhood Hits	471	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
NC score	0.083925 (rank : 289)	θ value	1.38821 (rank : 324)
Query Neighborhood Hits	471	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

GIPC2_MOUSE
NC score	0.079319 (rank : 290)	θ value	1.81305 (rank : 337)
Query Neighborhood Hits	471	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

TP4A2_HUMAN
NC score	0.076852 (rank : 291)	θ value	5.27518 (rank : 406)
Query Neighborhood Hits	471	Target Neighborhood Hits	56	Shared Neighborhood Hits	35
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.076852 (rank : 292)	θ value	5.27518 (rank : 407)
Query Neighborhood Hits	471	Target Neighborhood Hits	56	Shared Neighborhood Hits	35
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

DCC_HUMAN
NC score	0.075611 (rank : 293)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	471	Target Neighborhood Hits	583	Shared Neighborhood Hits	34
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

TP4A3_HUMAN
NC score	0.075278 (rank : 294)	θ value	8.99809 (rank : 470)
Query Neighborhood Hits	471	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

NEO1_MOUSE
NC score	0.074297 (rank : 295)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	471	Target Neighborhood Hits	523	Shared Neighborhood Hits	38
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

DCC_MOUSE
NC score	0.074017 (rank : 296)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	471	Target Neighborhood Hits	896	Shared Neighborhood Hits	50
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

RHPN2_MOUSE
NC score	0.072778 (rank : 297)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	471	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

NEO1_HUMAN
NC score	0.071463 (rank : 298)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	471	Target Neighborhood Hits	530	Shared Neighborhood Hits	35
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

TP4A3_MOUSE
NC score	0.070695 (rank : 299)	θ value	2.36792 (rank : 356)
Query Neighborhood Hits	471	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

MAMC2_MOUSE
NC score	0.069737 (rank : 300)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	471	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

KRIT1_HUMAN
NC score	0.069016 (rank : 301)	θ value	0.365318 (rank : 287)
Query Neighborhood Hits	471	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

TENN_MOUSE
NC score	0.068528 (rank : 302)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	471	Target Neighborhood Hits	484	Shared Neighborhood Hits	23
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

PTEN_HUMAN
NC score	0.068250 (rank : 303)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	471	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.068247 (rank : 304)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	471	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

COCA1_MOUSE
NC score	0.066860 (rank : 305)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	471	Target Neighborhood Hits	467	Shared Neighborhood Hits	26
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MAMC2_HUMAN
NC score	0.066841 (rank : 306)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	471	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

PRAX_MOUSE
NC score	0.065685 (rank : 307)	θ value	1.06291 (rank : 313)
Query Neighborhood Hits	471	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

COCA1_HUMAN
NC score	0.065339 (rank : 308)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	471	Target Neighborhood Hits	458	Shared Neighborhood Hits	28
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

KRIT1_MOUSE
NC score	0.064394 (rank : 309)	θ value	0.47712 (rank : 293)
Query Neighborhood Hits	471	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

SDK2_MOUSE
NC score	0.063109 (rank : 310)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	471	Target Neighborhood Hits	480	Shared Neighborhood Hits	29
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

DSPP_MOUSE
NC score	0.062899 (rank : 311)	θ value	7.1131e-05 (rank : 201)
Query Neighborhood Hits	471	Target Neighborhood Hits	491	Shared Neighborhood Hits	65
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

USH2A_HUMAN
NC score	0.061860 (rank : 312)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	471	Target Neighborhood Hits	600	Shared Neighborhood Hits	30
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LMO7_HUMAN
NC score	0.061516 (rank : 313)	θ value	6.88961 (rank : 424)
Query Neighborhood Hits	471	Target Neighborhood Hits	507	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

CSKP_HUMAN
NC score	0.061268 (rank : 314)	θ value	1.81305 (rank : 334)
Query Neighborhood Hits	471	Target Neighborhood Hits	1022	Shared Neighborhood Hits	133
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

SDK2_HUMAN
NC score	0.060563 (rank : 315)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	471	Target Neighborhood Hits	495	Shared Neighborhood Hits	28
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

MY18A_MOUSE
NC score	0.060397 (rank : 316)	θ value	0.0563607 (rank : 256)
Query Neighborhood Hits	471	Target Neighborhood Hits	1989	Shared Neighborhood Hits	204
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SDK1_MOUSE
NC score	0.060268 (rank : 317)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	471	Target Neighborhood Hits	495	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_HUMAN
NC score	0.059231 (rank : 318)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	471	Target Neighborhood Hits	511	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

CSKP_MOUSE
NC score	0.059077 (rank : 319)	θ value	1.81305 (rank : 335)
Query Neighborhood Hits	471	Target Neighborhood Hits	1027	Shared Neighborhood Hits	132
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

USH2A_MOUSE
NC score	0.058618 (rank : 320)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	471	Target Neighborhood Hits	626	Shared Neighborhood Hits	25
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

CAR11_HUMAN
NC score	0.058582 (rank : 321)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	471	Target Neighborhood Hits	690	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CDKN3_HUMAN
NC score	0.058452 (rank : 322)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	471	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

DSPP_HUMAN
NC score	0.058366 (rank : 323)	θ value	3.19293e-05 (rank : 198)
Query Neighborhood Hits	471	Target Neighborhood Hits	645	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TENN_HUMAN
NC score	0.058163 (rank : 324)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	471	Target Neighborhood Hits	453	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

MY18A_HUMAN
NC score	0.057065 (rank : 325)	θ value	0.279714 (rank : 282)
Query Neighborhood Hits	471	Target Neighborhood Hits	1929	Shared Neighborhood Hits	209
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TENR_HUMAN
NC score	0.056862 (rank : 326)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	471	Target Neighborhood Hits	526	Shared Neighborhood Hits	23
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB4_HUMAN
NC score	0.056789 (rank : 327)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	471	Target Neighborhood Hits	458	Shared Neighborhood Hits	21
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

TENR_MOUSE
NC score	0.056559 (rank : 328)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	471	Target Neighborhood Hits	531	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

PDZD8_HUMAN
NC score	0.056441 (rank : 329)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	471	Target Neighborhood Hits	185	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

TARSH_HUMAN
NC score	0.056147 (rank : 330)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	471	Target Neighborhood Hits	768	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CA106_HUMAN
NC score	0.056042 (rank : 331)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	471	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

L1CAM_MOUSE
NC score	0.054681 (rank : 332)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	471	Target Neighborhood Hits	457	Shared Neighborhood Hits	21
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

SRRM2_HUMAN
NC score	0.054516 (rank : 333)	θ value	0.0563607 (rank : 257)
Query Neighborhood Hits	471	Target Neighborhood Hits	1296	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CA106_MOUSE
NC score	0.054445 (rank : 334)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	471	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

COEA1_MOUSE
NC score	0.054441 (rank : 335)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	471	Target Neighborhood Hits	402	Shared Neighborhood Hits	22
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

L1CAM_HUMAN
NC score	0.054245 (rank : 336)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	471	Target Neighborhood Hits	457	Shared Neighborhood Hits	16
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

DSCL1_HUMAN
NC score	0.054083 (rank : 337)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	471	Target Neighborhood Hits	589	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

NRCAM_MOUSE
NC score	0.054081 (rank : 338)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	471	Target Neighborhood Hits	432	Shared Neighborhood Hits	17
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

DSCAM_HUMAN
NC score	0.053649 (rank : 339)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	471	Target Neighborhood Hits	524	Shared Neighborhood Hits	21
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

CO7A1_HUMAN
NC score	0.053320 (rank : 340)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	471	Target Neighborhood Hits	807	Shared Neighborhood Hits	41
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

RES18_MOUSE
NC score	0.053286 (rank : 341)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	471	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

CNTN5_HUMAN
NC score	0.052264 (rank : 342)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	471	Target Neighborhood Hits	446	Shared Neighborhood Hits	18
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

NRCAM_HUMAN
NC score	0.052246 (rank : 343)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	471	Target Neighborhood Hits	439	Shared Neighborhood Hits	15
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

TIAM1_HUMAN
NC score	0.051711 (rank : 344)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	471	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

MDGA1_HUMAN
NC score	0.051541 (rank : 345)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	471	Target Neighborhood Hits	358	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

CNTN5_MOUSE
NC score	0.051264 (rank : 346)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	471	Target Neighborhood Hits	434	Shared Neighborhood Hits	21
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

DMP1_MOUSE
NC score	0.051141 (rank : 347)	θ value	0.0330416 (rank : 246)
Query Neighborhood Hits	471	Target Neighborhood Hits	498	Shared Neighborhood Hits	56
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

PRAX_HUMAN
NC score	0.050505 (rank : 348)	θ value	5.27518 (rank : 399)
Query Neighborhood Hits	471	Target Neighborhood Hits	215	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

CNTN2_HUMAN
NC score	0.050445 (rank : 349)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	471	Target Neighborhood Hits	440	Shared Neighborhood Hits	15
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
NC score	0.050342 (rank : 350)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	471	Target Neighborhood Hits	450	Shared Neighborhood Hits	14
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

DMP1_HUMAN
NC score	0.046739 (rank : 351)	θ value	0.0736092 (rank : 258)
Query Neighborhood Hits	471	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PPRB_MOUSE
NC score	0.046216 (rank : 352)	θ value	0.00228821 (rank : 219)
Query Neighborhood Hits	471	Target Neighborhood Hits	354	Shared Neighborhood Hits	42
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SRRM2_MOUSE
NC score	0.045711 (rank : 353)	θ value	0.0431538 (rank : 253)
Query Neighborhood Hits	471	Target Neighborhood Hits	1470	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BCLF1_MOUSE
NC score	0.042846 (rank : 354)	θ value	0.0113563 (rank : 234)
Query Neighborhood Hits	471	Target Neighborhood Hits	303	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

PPRB_HUMAN
NC score	0.042035 (rank : 355)	θ value	0.0431538 (rank : 252)
Query Neighborhood Hits	471	Target Neighborhood Hits	311	Shared Neighborhood Hits	40
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

FILA_HUMAN
NC score	0.041415 (rank : 356)	θ value	0.0563607 (rank : 254)
Query Neighborhood Hits	471	Target Neighborhood Hits	685	Shared Neighborhood Hits	72
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

BCLF1_HUMAN
NC score	0.040680 (rank : 357)	θ value	0.00665767 (rank : 231)
Query Neighborhood Hits	471	Target Neighborhood Hits	298	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

AF9_HUMAN
NC score	0.038916 (rank : 358)	θ value	0.0148317 (rank : 237)
Query Neighborhood Hits	471	Target Neighborhood Hits	202	Shared Neighborhood Hits	22
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

SI1L2_MOUSE
NC score	0.037701 (rank : 359)	θ value	0.813845 (rank : 309)
Query Neighborhood Hits	471	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_HUMAN
NC score	0.037021 (rank : 360)	θ value	1.06291 (rank : 314)
Query Neighborhood Hits	471	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

PSMD9_HUMAN
NC score	0.036250 (rank : 361)	θ value	6.88961 (rank : 432)
Query Neighborhood Hits	471	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

SFR17_HUMAN
NC score	0.036171 (rank : 362)	θ value	0.813845 (rank : 308)
Query Neighborhood Hits	471	Target Neighborhood Hits	325	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SI1L1_HUMAN
NC score	0.035223 (rank : 363)	θ value	0.279714 (rank : 284)
Query Neighborhood Hits	471	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

CDSN_MOUSE
NC score	0.033819 (rank : 364)	θ value	0.0431538 (rank : 251)
Query Neighborhood Hits	471	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

LRC27_HUMAN
NC score	0.033349 (rank : 365)	θ value	4.03905 (rank : 370)
Query Neighborhood Hits	471	Target Neighborhood Hits	710	Shared Neighborhood Hits	50
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

SI1L1_MOUSE
NC score	0.032570 (rank : 366)	θ value	8.99809 (rank : 464)
Query Neighborhood Hits	471	Target Neighborhood Hits	189	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

HORN_MOUSE
NC score	0.030854 (rank : 367)	θ value	0.00509761 (rank : 228)
Query Neighborhood Hits	471	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

ZCH10_MOUSE
NC score	0.030578 (rank : 368)	θ value	0.365318 (rank : 291)
Query Neighborhood Hits	471	Target Neighborhood Hits	133	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

TXND2_MOUSE
NC score	0.029105 (rank : 369)	θ value	1.81305 (rank : 342)
Query Neighborhood Hits	471	Target Neighborhood Hits	828	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

SI1L3_HUMAN
NC score	0.028050 (rank : 370)	θ value	6.88961 (rank : 435)
Query Neighborhood Hits	471	Target Neighborhood Hits	305	Shared Neighborhood Hits	52
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

AKA12_HUMAN
NC score	0.026782 (rank : 371)	θ value	6.88961 (rank : 414)
Query Neighborhood Hits	471	Target Neighborhood Hits	825	Shared Neighborhood Hits	68
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DEK_MOUSE
NC score	0.026470 (rank : 372)	θ value	1.38821 (rank : 321)
Query Neighborhood Hits	471	Target Neighborhood Hits	280	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

MAST4_HUMAN
NC score	0.026233 (rank : 373)	θ value	0.0563607 (rank : 255)
Query Neighborhood Hits	471	Target Neighborhood Hits	1804	Shared Neighborhood Hits	176
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SIPA1_HUMAN
NC score	0.026003 (rank : 374)	θ value	8.99809 (rank : 465)
Query Neighborhood Hits	471	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

TNC6B_HUMAN
NC score	0.025973 (rank : 375)	θ value	0.21417 (rank : 281)
Query Neighborhood Hits	471	Target Neighborhood Hits	256	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

NOLC1_HUMAN
NC score	0.024861 (rank : 376)	θ value	1.06291 (rank : 312)
Query Neighborhood Hits	471	Target Neighborhood Hits	452	Shared Neighborhood Hits	44
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

CCD50_MOUSE
NC score	0.024682 (rank : 377)	θ value	1.81305 (rank : 333)
Query Neighborhood Hits	471	Target Neighborhood Hits	172	Shared Neighborhood Hits	24
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CHD9_MOUSE
NC score	0.023834 (rank : 378)	θ value	0.00665767 (rank : 232)
Query Neighborhood Hits	471	Target Neighborhood Hits	427	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

AFF4_MOUSE
NC score	0.023827 (rank : 379)	θ value	1.38821 (rank : 318)
Query Neighborhood Hits	471	Target Neighborhood Hits	581	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AUTS2_HUMAN
NC score	0.023504 (rank : 380)	θ value	0.163984 (rank : 269)
Query Neighborhood Hits	471	Target Neighborhood Hits	342	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

MAST2_HUMAN
NC score	0.023432 (rank : 381)	θ value	4.03905 (rank : 371)
Query Neighborhood Hits	471	Target Neighborhood Hits	1189	Shared Neighborhood Hits	137
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

CEP35_HUMAN
NC score	0.023392 (rank : 382)	θ value	0.21417 (rank : 272)
Query Neighborhood Hits	471	Target Neighborhood Hits	811	Shared Neighborhood Hits	68
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

MAST3_HUMAN
NC score	0.023371 (rank : 383)	θ value	3.0926 (rank : 363)
Query Neighborhood Hits	471	Target Neighborhood Hits	1128	Shared Neighborhood Hits	133
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

AKAP2_MOUSE
NC score	0.023358 (rank : 384)	θ value	1.81305 (rank : 328)
Query Neighborhood Hits	471	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

PRP40_MOUSE
NC score	0.023187 (rank : 385)	θ value	0.21417 (rank : 279)
Query Neighborhood Hits	471	Target Neighborhood Hits	447	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

NKTR_HUMAN
NC score	0.023079 (rank : 386)	θ value	8.99809 (rank : 461)
Query Neighborhood Hits	471	Target Neighborhood Hits	658	Shared Neighborhood Hits	76
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

ZCH10_HUMAN
NC score	0.022945 (rank : 387)	θ value	2.36792 (rank : 357)
Query Neighborhood Hits	471	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

PACS1_HUMAN
NC score	0.022819 (rank : 388)	θ value	0.47712 (rank : 294)
Query Neighborhood Hits	471	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

GOGA5_HUMAN
NC score	0.022816 (rank : 389)	θ value	6.88961 (rank : 423)
Query Neighborhood Hits	471	Target Neighborhood Hits	1168	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

ATRX_MOUSE
NC score	0.022161 (rank : 390)	θ value	1.81305 (rank : 331)
Query Neighborhood Hits	471	Target Neighborhood Hits	682	Shared Neighborhood Hits	76
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

PACS1_MOUSE
NC score	0.022111 (rank : 391)	θ value	0.813845 (rank : 305)
Query Neighborhood Hits	471	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

DEK_HUMAN
NC score	0.021691 (rank : 392)	θ value	3.0926 (rank : 360)
Query Neighborhood Hits	471	Target Neighborhood Hits	199	Shared Neighborhood Hits	22
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

MAST2_MOUSE
NC score	0.021442 (rank : 393)	θ value	4.03905 (rank : 372)
Query Neighborhood Hits	471	Target Neighborhood Hits	1110	Shared Neighborhood Hits	134
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

CCD37_MOUSE
NC score	0.021239 (rank : 394)	θ value	1.81305 (rank : 332)
Query Neighborhood Hits	471	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

RPTN_MOUSE
NC score	0.020949 (rank : 395)	θ value	2.36792 (rank : 351)
Query Neighborhood Hits	471	Target Neighborhood Hits	650	Shared Neighborhood Hits	57
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

TCF20_MOUSE
NC score	0.020775 (rank : 396)	θ value	1.38821 (rank : 327)
Query Neighborhood Hits	471	Target Neighborhood Hits	396	Shared Neighborhood Hits	54
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

RENT2_HUMAN
NC score	0.020056 (rank : 397)	θ value	2.36792 (rank : 349)
Query Neighborhood Hits	471	Target Neighborhood Hits	618	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

NCOR1_MOUSE
NC score	0.019832 (rank : 398)	θ value	2.36792 (rank : 347)
Query Neighborhood Hits	471	Target Neighborhood Hits	521	Shared Neighborhood Hits	54
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

SPRL1_HUMAN
NC score	0.019559 (rank : 399)	θ value	0.0961366 (rank : 263)
Query Neighborhood Hits	471	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SMDF_HUMAN
NC score	0.019526 (rank : 400)	θ value	0.279714 (rank : 285)
Query Neighborhood Hits	471	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

CHD9_HUMAN
NC score	0.019325 (rank : 401)	θ value	0.0193708 (rank : 240)
Query Neighborhood Hits	471	Target Neighborhood Hits	343	Shared Neighborhood Hits	34
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

GOG8A_HUMAN
NC score	0.018582 (rank : 402)	θ value	1.81305 (rank : 338)
Query Neighborhood Hits	471	Target Neighborhood Hits	635	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

SMC1A_HUMAN
NC score	0.017543 (rank : 403)	θ value	8.99809 (rank : 466)
Query Neighborhood Hits	471	Target Neighborhood Hits	1346	Shared Neighborhood Hits	64
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

AP3B1_MOUSE
NC score	0.016979 (rank : 404)	θ value	0.125558 (rank : 265)
Query Neighborhood Hits	471	Target Neighborhood Hits	302	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DUS5_HUMAN
NC score	0.016869 (rank : 405)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	471	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

CCD46_MOUSE
NC score	0.016866 (rank : 406)	θ value	5.27518 (rank : 391)
Query Neighborhood Hits	471	Target Neighborhood Hits	1405	Shared Neighborhood Hits	80
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

BRCA2_MOUSE
NC score	0.016830 (rank : 407)	θ value	0.813845 (rank : 301)
Query Neighborhood Hits	471	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

SMC1A_MOUSE
NC score	0.016607 (rank : 408)	θ value	8.99809 (rank : 467)
Query Neighborhood Hits	471	Target Neighborhood Hits	1384	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SET1A_HUMAN
NC score	0.016586 (rank : 409)	θ value	2.36792 (rank : 353)
Query Neighborhood Hits	471	Target Neighborhood Hits	690	Shared Neighborhood Hits	46
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

PRG4_HUMAN
NC score	0.016480 (rank : 410)	θ value	4.03905 (rank : 377)
Query Neighborhood Hits	471	Target Neighborhood Hits	764	Shared Neighborhood Hits	50
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SMUF1_MOUSE
NC score	0.015176 (rank : 411)	θ value	8.99809 (rank : 469)
Query Neighborhood Hits	471	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

CHD1_HUMAN
NC score	0.015107 (rank : 412)	θ value	0.47712 (rank : 292)
Query Neighborhood Hits	471	Target Neighborhood Hits	337	Shared Neighborhood Hits	33
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CENPF_HUMAN
NC score	0.014659 (rank : 413)	θ value	4.03905 (rank : 369)
Query Neighborhood Hits	471	Target Neighborhood Hits	1932	Shared Neighborhood Hits	89
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NKTR_MOUSE
NC score	0.014318 (rank : 414)	θ value	4.03905 (rank : 375)
Query Neighborhood Hits	471	Target Neighborhood Hits	417	Shared Neighborhood Hits	53
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

CCD37_HUMAN
NC score	0.014112 (rank : 415)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	471	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CI079_HUMAN
NC score	0.013901 (rank : 416)	θ value	6.88961 (rank : 417)
Query Neighborhood Hits	471	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

SMUF1_HUMAN
NC score	0.013873 (rank : 417)	θ value	8.99809 (rank : 468)
Query Neighborhood Hits	471	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

CMGA_MOUSE
NC score	0.013605 (rank : 418)	θ value	5.27518 (rank : 393)
Query Neighborhood Hits	471	Target Neighborhood Hits	172	Shared Neighborhood Hits	24
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

UBP47_HUMAN
NC score	0.013392 (rank : 419)	θ value	1.06291 (rank : 317)
Query Neighborhood Hits	471	Target Neighborhood Hits	149	Shared Neighborhood Hits	18
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

APC_MOUSE
NC score	0.012576 (rank : 420)	θ value	1.81305 (rank : 329)
Query Neighborhood Hits	471	Target Neighborhood Hits	441	Shared Neighborhood Hits	41
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

EXO1_MOUSE
NC score	0.012568 (rank : 421)	θ value	6.88961 (rank : 422)
Query Neighborhood Hits	471	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

AP3B1_HUMAN
NC score	0.012441 (rank : 422)	θ value	6.88961 (rank : 416)
Query Neighborhood Hits	471	Target Neighborhood Hits	283	Shared Neighborhood Hits	32
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CHD1_MOUSE
NC score	0.012398 (rank : 423)	θ value	1.38821 (rank : 319)
Query Neighborhood Hits	471	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

MYH8_MOUSE
NC score	0.012361 (rank : 424)	θ value	4.03905 (rank : 374)
Query Neighborhood Hits	471	Target Neighborhood Hits	1600	Shared Neighborhood Hits	72
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CHD2_HUMAN
NC score	0.012290 (rank : 425)	θ value	5.27518 (rank : 392)
Query Neighborhood Hits	471	Target Neighborhood Hits	360	Shared Neighborhood Hits	38
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

ACINU_MOUSE
NC score	0.012182 (rank : 426)	θ value	6.88961 (rank : 413)
Query Neighborhood Hits	471	Target Neighborhood Hits	712	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

WASF3_MOUSE
NC score	0.012117 (rank : 427)	θ value	3.0926 (rank : 366)
Query Neighborhood Hits	471	Target Neighborhood Hits	188	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

CIR_HUMAN
NC score	0.012114 (rank : 428)	θ value	6.88961 (rank : 418)
Query Neighborhood Hits	471	Target Neighborhood Hits	249	Shared Neighborhood Hits	29
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

ANR26_MOUSE
NC score	0.012040 (rank : 429)	θ value	6.88961 (rank : 415)
Query Neighborhood Hits	471	Target Neighborhood Hits	1554	Shared Neighborhood Hits	70
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ALMS1_HUMAN
NC score	0.011933 (rank : 430)	θ value	4.03905 (rank : 367)
Query Neighborhood Hits	471	Target Neighborhood Hits	356	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

K0528_MOUSE
NC score	0.011877 (rank : 431)	θ value	1.06291 (rank : 311)
Query Neighborhood Hits	471	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

RAI1_HUMAN
NC score	0.011770 (rank : 432)	θ value	5.27518 (rank : 400)
Query Neighborhood Hits	471	Target Neighborhood Hits	360	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

KIF4A_HUMAN
NC score	0.011566 (rank : 433)	θ value	2.36792 (rank : 346)
Query Neighborhood Hits	471	Target Neighborhood Hits	1159	Shared Neighborhood Hits	62
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

ZCH11_HUMAN
NC score	0.011508 (rank : 434)	θ value	5.27518 (rank : 412)
Query Neighborhood Hits	471	Target Neighborhood Hits	278	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

RNPS1_HUMAN
NC score	0.011327 (rank : 435)	θ value	4.03905 (rank : 378)
Query Neighborhood Hits	471	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.011327 (rank : 436)	θ value	4.03905 (rank : 379)
Query Neighborhood Hits	471	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

SFRS4_HUMAN
NC score	0.011273 (rank : 437)	θ value	0.62314 (rank : 300)
Query Neighborhood Hits	471	Target Neighborhood Hits	384	Shared Neighborhood Hits	33
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

LIMK2_MOUSE
NC score	0.011075 (rank : 438)	θ value	0.21417 (rank : 277)
Query Neighborhood Hits	471	Target Neighborhood Hits	998	Shared Neighborhood Hits	77
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

DPOLZ_HUMAN
NC score	0.011066 (rank : 439)	θ value	3.0926 (rank : 361)
Query Neighborhood Hits	471	Target Neighborhood Hits	200	Shared Neighborhood Hits	25
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

MYH8_HUMAN
NC score	0.011008 (rank : 440)	θ value	8.99809 (rank : 457)
Query Neighborhood Hits	471	Target Neighborhood Hits	1610	Shared Neighborhood Hits	73
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SYCP2_HUMAN
NC score	0.010819 (rank : 441)	θ value	4.03905 (rank : 384)
Query Neighborhood Hits	471	Target Neighborhood Hits	230	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

RECQ4_MOUSE
NC score	0.010439 (rank : 442)	θ value	0.21417 (rank : 280)
Query Neighborhood Hits	471	Target Neighborhood Hits	206	Shared Neighborhood Hits	9
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DLGP4_HUMAN
NC score	0.010154 (rank : 443)	θ value	0.62314 (rank : 298)
Query Neighborhood Hits	471	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

WASF3_HUMAN
NC score	0.009628 (rank : 444)	θ value	4.03905 (rank : 390)
Query Neighborhood Hits	471	Target Neighborhood Hits	204	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

TPP2_HUMAN
NC score	0.009607 (rank : 445)	θ value	5.27518 (rank : 408)
Query Neighborhood Hits	471	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P29144	Gene names	TPP2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

ANK2_HUMAN
NC score	0.009538 (rank : 446)	θ value	3.0926 (rank : 358)
Query Neighborhood Hits	471	Target Neighborhood Hits	1615	Shared Neighborhood Hits	116
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

UBP47_MOUSE
NC score	0.009479 (rank : 447)	θ value	0.813845 (rank : 310)
Query Neighborhood Hits	471	Target Neighborhood Hits	135	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

SETBP_HUMAN
NC score	0.009425 (rank : 448)	θ value	4.03905 (rank : 382)
Query Neighborhood Hits	471	Target Neighborhood Hits	305	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

LIMK1_HUMAN
NC score	0.009314 (rank : 449)	θ value	0.125558 (rank : 268)
Query Neighborhood Hits	471	Target Neighborhood Hits	1005	Shared Neighborhood Hits	88
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

TPP2_MOUSE
NC score	0.008882 (rank : 450)	θ value	5.27518 (rank : 409)
Query Neighborhood Hits	471	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q64514	Gene names	Tpp2
Domain Architecture
Description	Tripeptidyl-peptidase 2 (EC 3.4.14.10) (Tripeptidyl-peptidase II) (TPP-II) (Tripeptidyl aminopeptidase).

SAPS3_HUMAN
NC score	0.008781 (rank : 451)	θ value	0.813845 (rank : 307)
Query Neighborhood Hits	471	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q5H9R7, Q3B7I1, Q3I4Y0, Q3KR35, Q68CR3, Q7L4R8, Q8N3B2, Q96MB2, Q9H2K5, Q9H2K6, Q9HCL4, Q9NUY3	Gene names	SAPS3, C11orf23, KIAA1558, PP6R3, SAPL
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3 (Sporulation-induced transcript 4- associated protein SAPL) (Protein phosphatase 6 regulatory subunit 3).

NTKL_HUMAN
NC score	0.008732 (rank : 452)	θ value	4.03905 (rank : 376)
Query Neighborhood Hits	471	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

LIMK1_MOUSE
NC score	0.008621 (rank : 453)	θ value	0.163984 (rank : 271)
Query Neighborhood Hits	471	Target Neighborhood Hits	1008	Shared Neighborhood Hits	90
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

LRRN3_MOUSE
NC score	0.008608 (rank : 454)	θ value	5.27518 (rank : 396)
Query Neighborhood Hits	471	Target Neighborhood Hits	455	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

PHF2_MOUSE
NC score	0.008571 (rank : 455)	θ value	2.36792 (rank : 348)
Query Neighborhood Hits	471	Target Neighborhood Hits	241	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

K0319_MOUSE
NC score	0.008552 (rank : 456)	θ value	2.36792 (rank : 345)
Query Neighborhood Hits	471	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

RFIP1_HUMAN
NC score	0.008319 (rank : 457)	θ value	6.88961 (rank : 433)
Query Neighborhood Hits	471	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

LIMK2_HUMAN
NC score	0.008247 (rank : 458)	θ value	1.38821 (rank : 325)
Query Neighborhood Hits	471	Target Neighborhood Hits	986	Shared Neighborhood Hits	79
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

MYH1_MOUSE
NC score	0.008142 (rank : 459)	θ value	8.99809 (rank : 455)
Query Neighborhood Hits	471	Target Neighborhood Hits	1461	Shared Neighborhood Hits	61
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYST4_HUMAN
NC score	0.008007 (rank : 460)	θ value	8.99809 (rank : 458)
Query Neighborhood Hits	471	Target Neighborhood Hits	671	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

ARI4A_HUMAN
NC score	0.007825 (rank : 461)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	471	Target Neighborhood Hits	434	Shared Neighborhood Hits	42
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

RUVB2_MOUSE
NC score	0.007723 (rank : 462)	θ value	4.03905 (rank : 381)
Query Neighborhood Hits	471	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

RUVB2_HUMAN
NC score	0.007709 (rank : 463)	θ value	4.03905 (rank : 380)
Query Neighborhood Hits	471	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

NPM2_MOUSE
NC score	0.007420 (rank : 464)	θ value	5.27518 (rank : 397)
Query Neighborhood Hits	471	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W85, Q8BW23	Gene names	Npm2
Domain Architecture
Description	Nucleoplasmin-2.

UBP34_MOUSE
NC score	0.007353 (rank : 465)	θ value	5.27518 (rank : 411)
Query Neighborhood Hits	471	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.007310 (rank : 466)	θ value	5.27518 (rank : 410)
Query Neighborhood Hits	471	Target Neighborhood Hits	210	Shared Neighborhood Hits	19
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

CSPG2_MOUSE
NC score	0.007271 (rank : 467)	θ value	1.38821 (rank : 320)
Query Neighborhood Hits	471	Target Neighborhood Hits	711	Shared Neighborhood Hits	33
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

PHF2_HUMAN
NC score	0.007091 (rank : 468)	θ value	3.0926 (rank : 365)
Query Neighborhood Hits	471	Target Neighborhood Hits	208	Shared Neighborhood Hits	14
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

MUCDL_MOUSE
NC score	0.007054 (rank : 469)	θ value	3.0926 (rank : 364)
Query Neighborhood Hits	471	Target Neighborhood Hits	461	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NFAT5_HUMAN
NC score	0.007003 (rank : 470)	θ value	0.813845 (rank : 304)
Query Neighborhood Hits	471	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

ANR18_HUMAN
NC score	0.006912 (rank : 471)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	471	Target Neighborhood Hits	1106	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

MYH4_HUMAN
NC score	0.006749 (rank : 472)	θ value	8.99809 (rank : 456)
Query Neighborhood Hits	471	Target Neighborhood Hits	1377	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

NFAC1_HUMAN
NC score	0.006421 (rank : 473)	θ value	6.88961 (rank : 427)
Query Neighborhood Hits	471	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

TYDP1_MOUSE
NC score	0.006262 (rank : 474)	θ value	6.88961 (rank : 438)
Query Neighborhood Hits	471	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJ37, Q8VE39	Gene names	Tdp1
Domain Architecture
Description	Tyrosyl-DNA phosphodiesterase 1 (EC 3.1.4.-) (Tyr-DNA phosphodiesterase 1).

LSR_HUMAN
NC score	0.006221 (rank : 475)	θ value	8.99809 (rank : 454)
Query Neighborhood Hits	471	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

DCP1A_MOUSE
NC score	0.006026 (rank : 476)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	471	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

CU055_HUMAN
NC score	0.005566 (rank : 477)	θ value	3.0926 (rank : 359)
Query Neighborhood Hits	471	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NX36	Gene names	C21orf55
Domain Architecture
Description	J domain-containing protein C21orf55.

RGP1_HUMAN
NC score	0.005231 (rank : 478)	θ value	5.27518 (rank : 403)
Query Neighborhood Hits	471	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

YAF2_MOUSE
NC score	0.005184 (rank : 479)	θ value	6.88961 (rank : 439)
Query Neighborhood Hits	471	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LW6, Q3UFD4, Q9DBE4	Gene names	Yaf2
Domain Architecture
Description	YY1-associated factor 2.

MYT1_HUMAN
NC score	0.004982 (rank : 480)	θ value	8.99809 (rank : 459)
Query Neighborhood Hits	471	Target Neighborhood Hits	475	Shared Neighborhood Hits	34
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

CUL4B_HUMAN
NC score	0.004360 (rank : 481)	θ value	1.81305 (rank : 336)
Query Neighborhood Hits	471	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

CSPG2_HUMAN
NC score	0.004119 (rank : 482)	θ value	0.125558 (rank : 266)
Query Neighborhood Hits	471	Target Neighborhood Hits	681	Shared Neighborhood Hits	24
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

DMRTA_HUMAN
NC score	0.003972 (rank : 483)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	471	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

RHG12_MOUSE
NC score	0.003872 (rank : 484)	θ value	5.27518 (rank : 404)
Query Neighborhood Hits	471	Target Neighborhood Hits	204	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SAMD4_MOUSE
NC score	0.003709 (rank : 485)	θ value	8.99809 (rank : 463)
Query Neighborhood Hits	471	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

RHG18_MOUSE
NC score	0.003661 (rank : 486)	θ value	2.36792 (rank : 350)
Query Neighborhood Hits	471	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

F120A_HUMAN
NC score	0.003219 (rank : 487)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	471	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZB2, O60649, Q14688, Q4VXF4, Q4VXF5, Q4VXG2, Q96I21, Q9NZB1	Gene names	FAM120A, C9orf10, KIAA0183
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120A.

UBP36_HUMAN
NC score	0.003144 (rank : 488)	θ value	4.03905 (rank : 389)
Query Neighborhood Hits	471	Target Neighborhood Hits	232	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

TF7L2_MOUSE
NC score	0.002710 (rank : 489)	θ value	4.03905 (rank : 386)
Query Neighborhood Hits	471	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TF7L2_HUMAN
NC score	0.002587 (rank : 490)	θ value	4.03905 (rank : 385)
Query Neighborhood Hits	471	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

DGKH_HUMAN
NC score	0.002276 (rank : 491)	θ value	6.88961 (rank : 420)
Query Neighborhood Hits	471	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

TRPM3_HUMAN
NC score	0.002014 (rank : 492)	θ value	4.03905 (rank : 387)
Query Neighborhood Hits	471	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

SPTB1_HUMAN
NC score	0.001935 (rank : 493)	θ value	6.88961 (rank : 436)
Query Neighborhood Hits	471	Target Neighborhood Hits	541	Shared Neighborhood Hits	31
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

ANKZ1_HUMAN
NC score	0.001896 (rank : 494)	θ value	8.99809 (rank : 440)
Query Neighborhood Hits	471	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

TRPS1_MOUSE
NC score	0.001770 (rank : 495)	θ value	4.03905 (rank : 388)
Query Neighborhood Hits	471	Target Neighborhood Hits	609	Shared Neighborhood Hits	15
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

G3BP_HUMAN
NC score	0.001578 (rank : 496)	θ value	5.27518 (rank : 394)
Query Neighborhood Hits	471	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

GRLF1_HUMAN
NC score	0.001497 (rank : 497)	θ value	5.27518 (rank : 395)
Query Neighborhood Hits	471	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

TAOK1_MOUSE
NC score	0.001347 (rank : 498)	θ value	1.06291 (rank : 316)
Query Neighborhood Hits	471	Target Neighborhood Hits	1720	Shared Neighborhood Hits	72
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

DC1I2_MOUSE
NC score	0.001185 (rank : 499)	θ value	6.88961 (rank : 419)
Query Neighborhood Hits	471	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

CREB5_HUMAN
NC score	0.001167 (rank : 500)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	471	Target Neighborhood Hits	222	Shared Neighborhood Hits	9
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

TAOK1_HUMAN
NC score	0.001020 (rank : 501)	θ value	1.06291 (rank : 315)
Query Neighborhood Hits	471	Target Neighborhood Hits	1734	Shared Neighborhood Hits	72
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

DDX21_HUMAN
NC score	0.000770 (rank : 502)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	471	Target Neighborhood Hits	308	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

STK10_HUMAN
NC score	0.000458 (rank : 503)	θ value	6.88961 (rank : 437)
Query Neighborhood Hits	471	Target Neighborhood Hits	1921	Shared Neighborhood Hits	81
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

K1C18_HUMAN
NC score	-0.000150 (rank : 504)	θ value	8.99809 (rank : 453)
Query Neighborhood Hits	471	Target Neighborhood Hits	441	Shared Neighborhood Hits	26
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

SC11A_HUMAN
NC score	-0.000184 (rank : 505)	θ value	2.36792 (rank : 352)
Query Neighborhood Hits	471	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

K1802_MOUSE
NC score	-0.000429 (rank : 506)	θ value	3.0926 (rank : 362)
Query Neighborhood Hits	471	Target Neighborhood Hits	1596	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TSH3_MOUSE
NC score	-0.000690 (rank : 507)	θ value	8.99809 (rank : 471)
Query Neighborhood Hits	471	Target Neighborhood Hits	590	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

PO5FN_HUMAN
NC score	-0.001145 (rank : 508)	θ value	6.88961 (rank : 431)
Query Neighborhood Hits	471	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZW0	Gene names	POU5FLC1
Domain Architecture
Description	POU domain, class 5, transcription factor 1-like protein 3.

SLK_MOUSE
NC score	-0.001251 (rank : 509)	θ value	5.27518 (rank : 405)
Query Neighborhood Hits	471	Target Neighborhood Hits	1798	Shared Neighborhood Hits	80
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TAOK3_MOUSE
NC score	-0.001407 (rank : 510)	θ value	1.38821 (rank : 326)
Query Neighborhood Hits	471	Target Neighborhood Hits	1458	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

TAOK3_HUMAN
NC score	-0.001743 (rank : 511)	θ value	1.81305 (rank : 341)
Query Neighborhood Hits	471	Target Neighborhood Hits	1494	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

ATL2_MOUSE
NC score	-0.002131 (rank : 512)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	471	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

MRCKG_HUMAN
NC score	-0.002384 (rank : 513)	θ value	4.03905 (rank : 373)
Query Neighborhood Hits	471	Target Neighborhood Hits	1519	Shared Neighborhood Hits	62
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

NID2_HUMAN
NC score	-0.004581 (rank : 514)	θ value	8.99809 (rank : 460)
Query Neighborhood Hits	471	Target Neighborhood Hits	456	Shared Neighborhood Hits	9
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

PCDBB_HUMAN
NC score	-0.004703 (rank : 515)	θ value	6.88961 (rank : 428)
Query Neighborhood Hits	471	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5F2	Gene names	PCDHB11
Domain Architecture
Description	Protocadherin beta 11 precursor (PCDH-beta11).

PCDBC_HUMAN
NC score	-0.004719 (rank : 516)	θ value	6.88961 (rank : 429)
Query Neighborhood Hits	471	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5F1	Gene names	PCDHB12
Domain Architecture
Description	Protocadherin beta 12 precursor (PCDH-beta12).

MP2K4_MOUSE
NC score	-0.004785 (rank : 517)	θ value	0.365318 (rank : 289)
Query Neighborhood Hits	471	Target Neighborhood Hits	833	Shared Neighborhood Hits	24
SwissProt Accessions	P47809	Gene names	Map2k4, Jnkk1, Prkmk4, Sek1, Serk1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SEK1).

MP2K4_HUMAN
NC score	-0.004813 (rank : 518)	θ value	0.365318 (rank : 288)
Query Neighborhood Hits	471	Target Neighborhood Hits	832	Shared Neighborhood Hits	24
SwissProt Accessions	P45985, Q5U0B8	Gene names	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 4 (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).

CD2L1_MOUSE
NC score	-0.005717 (rank : 519)	θ value	4.03905 (rank : 368)
Query Neighborhood Hits	471	Target Neighborhood Hits	1463	Shared Neighborhood Hits	69
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

RASN_MOUSE
NC score	-0.006039 (rank : 520)	θ value	5.27518 (rank : 402)
Query Neighborhood Hits	471	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P08556	Gene names	Nras
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

RASN_HUMAN
NC score	-0.006040 (rank : 521)	θ value	5.27518 (rank : 401)
Query Neighborhood Hits	471	Target Neighborhood Hits	259	Shared Neighborhood Hits	4
SwissProt Accessions	P01111, Q14971, Q15104, Q15282	Gene names	NRAS
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

PAX3_HUMAN
NC score	-0.006464 (rank : 522)	θ value	8.99809 (rank : 462)
Query Neighborhood Hits	471	Target Neighborhood Hits	513	Shared Neighborhood Hits	14
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

BMP2K_MOUSE
NC score	-0.007108 (rank : 523)	θ value	2.36792 (rank : 343)
Query Neighborhood Hits	471	Target Neighborhood Hits	874	Shared Neighborhood Hits	27
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

ATBF1_MOUSE
NC score	-0.007569 (rank : 524)	θ value	1.81305 (rank : 330)
Query Neighborhood Hits	471	Target Neighborhood Hits	1841	Shared Neighborhood Hits	75
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

SP4_MOUSE
NC score	-0.011811 (rank : 525)	θ value	4.03905 (rank : 383)
Query Neighborhood Hits	471	Target Neighborhood Hits	759	Shared Neighborhood Hits	12
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

GLIS3_HUMAN
NC score	-0.013052 (rank : 526)	θ value	8.99809 (rank : 452)
Query Neighborhood Hits	471	Target Neighborhood Hits	758	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).