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Network neighborhood for query Sequence : ITB4_HUMAN

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ITB4_HUMAN
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ITB4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	458	Target Neighborhood Hits	458	Shared Neighborhood Hits	458
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB1_HUMAN
θ value	1.69212e-123 (rank : 2)	NC score	0.815970 (rank : 8)
Query Neighborhood Hits	458	Target Neighborhood Hits	298	Shared Neighborhood Hits	195
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB3_MOUSE
θ value	1.43246e-122 (rank : 3)	NC score	0.814092 (rank : 10)
Query Neighborhood Hits	458	Target Neighborhood Hits	319	Shared Neighborhood Hits	200
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_HUMAN
θ value	7.86017e-121 (rank : 4)	NC score	0.813260 (rank : 13)
Query Neighborhood Hits	458	Target Neighborhood Hits	325	Shared Neighborhood Hits	208
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB1_MOUSE
θ value	6.65404e-120 (rank : 5)	NC score	0.818767 (rank : 4)
Query Neighborhood Hits	458	Target Neighborhood Hits	283	Shared Neighborhood Hits	195
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB5_MOUSE
θ value	2.5344e-111 (rank : 6)	NC score	0.815496 (rank : 9)
Query Neighborhood Hits	458	Target Neighborhood Hits	329	Shared Neighborhood Hits	218
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_HUMAN
θ value	7.37397e-111 (rank : 7)	NC score	0.816903 (rank : 7)
Query Neighborhood Hits	458	Target Neighborhood Hits	310	Shared Neighborhood Hits	214
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_MOUSE
θ value	1.25781e-110 (rank : 8)	NC score	0.823552 (rank : 3)
Query Neighborhood Hits	458	Target Neighborhood Hits	341	Shared Neighborhood Hits	224
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_HUMAN
θ value	2.1455e-110 (rank : 9)	NC score	0.826157 (rank : 2)
Query Neighborhood Hits	458	Target Neighborhood Hits	318	Shared Neighborhood Hits	225
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_MOUSE
θ value	2.80862e-102 (rank : 10)	NC score	0.818387 (rank : 6)
Query Neighborhood Hits	458	Target Neighborhood Hits	277	Shared Neighborhood Hits	210
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB2_MOUSE
θ value	3.4333e-100 (rank : 11)	NC score	0.813474 (rank : 12)
Query Neighborhood Hits	458	Target Neighborhood Hits	326	Shared Neighborhood Hits	225
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB7_HUMAN
θ value	8.4565e-99 (rank : 12)	NC score	0.818457 (rank : 5)
Query Neighborhood Hits	458	Target Neighborhood Hits	290	Shared Neighborhood Hits	211
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB2_HUMAN
θ value	1.03374e-96 (rank : 13)	NC score	0.813717 (rank : 11)
Query Neighborhood Hits	458	Target Neighborhood Hits	282	Shared Neighborhood Hits	206
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB8_HUMAN
θ value	3.81361e-83 (rank : 14)	NC score	0.802012 (rank : 14)
Query Neighborhood Hits	458	Target Neighborhood Hits	280	Shared Neighborhood Hits	186
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

SDK1_MOUSE
θ value	2.51237e-26 (rank : 15)	NC score	0.432842 (rank : 72)
Query Neighborhood Hits	458	Target Neighborhood Hits	495	Shared Neighborhood Hits	164
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

PTPRD_HUMAN
θ value	1.42661e-21 (rank : 16)	NC score	0.378691 (rank : 129)
Query Neighborhood Hits	458	Target Neighborhood Hits	485	Shared Neighborhood Hits	167
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	5.42112e-21 (rank : 17)	NC score	0.376170 (rank : 133)
Query Neighborhood Hits	458	Target Neighborhood Hits	491	Shared Neighborhood Hits	161
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

SDK1_HUMAN
θ value	3.51386e-20 (rank : 18)	NC score	0.427209 (rank : 80)
Query Neighborhood Hits	458	Target Neighborhood Hits	511	Shared Neighborhood Hits	166
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

PTPRS_HUMAN
θ value	2.27762e-19 (rank : 19)	NC score	0.368200 (rank : 145)
Query Neighborhood Hits	458	Target Neighborhood Hits	472	Shared Neighborhood Hits	158
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

SDK2_MOUSE
θ value	2.27762e-19 (rank : 20)	NC score	0.432018 (rank : 74)
Query Neighborhood Hits	458	Target Neighborhood Hits	480	Shared Neighborhood Hits	163
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

TENX_HUMAN
θ value	9.56915e-18 (rank : 21)	NC score	0.611129 (rank : 15)
Query Neighborhood Hits	458	Target Neighborhood Hits	789	Shared Neighborhood Hits	371
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TENR_MOUSE
θ value	6.20254e-17 (rank : 22)	NC score	0.587335 (rank : 19)
Query Neighborhood Hits	458	Target Neighborhood Hits	531	Shared Neighborhood Hits	331
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENA_HUMAN
θ value	8.10077e-17 (rank : 23)	NC score	0.600182 (rank : 16)
Query Neighborhood Hits	458	Target Neighborhood Hits	631	Shared Neighborhood Hits	362
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENR_HUMAN
θ value	1.058e-16 (rank : 24)	NC score	0.587822 (rank : 18)
Query Neighborhood Hits	458	Target Neighborhood Hits	526	Shared Neighborhood Hits	330
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

SDK2_HUMAN
θ value	1.38178e-16 (rank : 25)	NC score	0.427108 (rank : 81)
Query Neighborhood Hits	458	Target Neighborhood Hits	495	Shared Neighborhood Hits	160
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

TENA_MOUSE
θ value	4.44505e-15 (rank : 26)	NC score	0.590516 (rank : 17)
Query Neighborhood Hits	458	Target Neighborhood Hits	596	Shared Neighborhood Hits	350
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

PTPRF_HUMAN
θ value	2.20605e-14 (rank : 27)	NC score	0.368224 (rank : 144)
Query Neighborhood Hits	458	Target Neighborhood Hits	489	Shared Neighborhood Hits	160
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

DLL4_HUMAN
θ value	1.09485e-13 (rank : 28)	NC score	0.507886 (rank : 36)
Query Neighborhood Hits	458	Target Neighborhood Hits	435	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	2.43908e-13 (rank : 29)	NC score	0.508144 (rank : 35)
Query Neighborhood Hits	458	Target Neighborhood Hits	440	Shared Neighborhood Hits	248
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG1_MOUSE
θ value	3.18553e-13 (rank : 30)	NC score	0.493692 (rank : 42)
Query Neighborhood Hits	458	Target Neighborhood Hits	518	Shared Neighborhood Hits	256
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
θ value	5.43371e-13 (rank : 31)	NC score	0.492801 (rank : 43)
Query Neighborhood Hits	458	Target Neighborhood Hits	514	Shared Neighborhood Hits	253
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

MEGF6_HUMAN
θ value	2.0648e-12 (rank : 32)	NC score	0.481770 (rank : 48)
Query Neighborhood Hits	458	Target Neighborhood Hits	671	Shared Neighborhood Hits	274
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NRCAM_MOUSE
θ value	2.69671e-12 (rank : 33)	NC score	0.396876 (rank : 103)
Query Neighborhood Hits	458	Target Neighborhood Hits	432	Shared Neighborhood Hits	149
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

L1CAM_HUMAN
θ value	7.84624e-12 (rank : 34)	NC score	0.397517 (rank : 102)
Query Neighborhood Hits	458	Target Neighborhood Hits	457	Shared Neighborhood Hits	155
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

DSCAM_HUMAN
θ value	1.02475e-11 (rank : 35)	NC score	0.379219 (rank : 128)
Query Neighborhood Hits	458	Target Neighborhood Hits	524	Shared Neighborhood Hits	156
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DLK_HUMAN
θ value	1.33837e-11 (rank : 36)	NC score	0.517039 (rank : 32)
Query Neighborhood Hits	458	Target Neighborhood Hits	401	Shared Neighborhood Hits	247
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	1.33837e-11 (rank : 37)	NC score	0.505998 (rank : 37)
Query Neighborhood Hits	458	Target Neighborhood Hits	374	Shared Neighborhood Hits	238
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

NEO1_HUMAN
θ value	1.33837e-11 (rank : 38)	NC score	0.411437 (rank : 90)
Query Neighborhood Hits	458	Target Neighborhood Hits	530	Shared Neighborhood Hits	164
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

JAG2_MOUSE
θ value	1.74796e-11 (rank : 39)	NC score	0.485230 (rank : 47)
Query Neighborhood Hits	458	Target Neighborhood Hits	504	Shared Neighborhood Hits	253
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

TENN_MOUSE
θ value	1.74796e-11 (rank : 40)	NC score	0.551562 (rank : 22)
Query Neighborhood Hits	458	Target Neighborhood Hits	484	Shared Neighborhood Hits	319
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CHL1_MOUSE
θ value	2.28291e-11 (rank : 41)	NC score	0.374211 (rank : 137)
Query Neighborhood Hits	458	Target Neighborhood Hits	402	Shared Neighborhood Hits	138
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

NRCAM_HUMAN
θ value	2.28291e-11 (rank : 42)	NC score	0.403862 (rank : 97)
Query Neighborhood Hits	458	Target Neighborhood Hits	439	Shared Neighborhood Hits	150
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

MYOM1_HUMAN
θ value	2.98157e-11 (rank : 43)	NC score	0.391991 (rank : 115)
Query Neighborhood Hits	458	Target Neighborhood Hits	405	Shared Neighborhood Hits	142
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NEO1_MOUSE
θ value	5.08577e-11 (rank : 44)	NC score	0.412190 (rank : 89)
Query Neighborhood Hits	458	Target Neighborhood Hits	523	Shared Neighborhood Hits	165
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

CNTN4_HUMAN
θ value	8.67504e-11 (rank : 45)	NC score	0.359950 (rank : 158)
Query Neighborhood Hits	458	Target Neighborhood Hits	449	Shared Neighborhood Hits	135
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

JAG2_HUMAN
θ value	8.67504e-11 (rank : 46)	NC score	0.481371 (rank : 49)
Query Neighborhood Hits	458	Target Neighborhood Hits	491	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

TITIN_HUMAN
θ value	8.67504e-11 (rank : 47)	NC score	0.215087 (rank : 340)
Query Neighborhood Hits	458	Target Neighborhood Hits	2923	Shared Neighborhood Hits	211
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

NOTC1_MOUSE
θ value	1.47974e-10 (rank : 48)	NC score	0.444380 (rank : 66)
Query Neighborhood Hits	458	Target Neighborhood Hits	916	Shared Neighborhood Hits	260
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	1.47974e-10 (rank : 49)	NC score	0.427369 (rank : 79)
Query Neighborhood Hits	458	Target Neighborhood Hits	1113	Shared Neighborhood Hits	271
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TIE1_MOUSE
θ value	1.47974e-10 (rank : 50)	NC score	0.279388 (rank : 245)
Query Neighborhood Hits	458	Target Neighborhood Hits	1266	Shared Neighborhood Hits	332
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CHL1_HUMAN
θ value	2.52405e-10 (rank : 51)	NC score	0.382842 (rank : 127)
Query Neighborhood Hits	458	Target Neighborhood Hits	413	Shared Neighborhood Hits	140
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

NOTC1_HUMAN
θ value	4.30538e-10 (rank : 52)	NC score	0.434772 (rank : 68)
Query Neighborhood Hits	458	Target Neighborhood Hits	906	Shared Neighborhood Hits	260
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CNTN4_MOUSE
θ value	5.62301e-10 (rank : 53)	NC score	0.358717 (rank : 160)
Query Neighborhood Hits	458	Target Neighborhood Hits	445	Shared Neighborhood Hits	135
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN3_MOUSE
θ value	7.34386e-10 (rank : 54)	NC score	0.378666 (rank : 130)
Query Neighborhood Hits	458	Target Neighborhood Hits	447	Shared Neighborhood Hits	147
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

NOTC4_HUMAN
θ value	7.34386e-10 (rank : 55)	NC score	0.422995 (rank : 84)
Query Neighborhood Hits	458	Target Neighborhood Hits	905	Shared Neighborhood Hits	267
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TENN_HUMAN
θ value	7.34386e-10 (rank : 56)	NC score	0.527783 (rank : 28)
Query Neighborhood Hits	458	Target Neighborhood Hits	453	Shared Neighborhood Hits	300
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CNTN3_HUMAN
θ value	9.59137e-10 (rank : 57)	NC score	0.376322 (rank : 132)
Query Neighborhood Hits	458	Target Neighborhood Hits	455	Shared Neighborhood Hits	151
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

L1CAM_MOUSE
θ value	9.59137e-10 (rank : 58)	NC score	0.388640 (rank : 119)
Query Neighborhood Hits	458	Target Neighborhood Hits	457	Shared Neighborhood Hits	157
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

DLL1_MOUSE
θ value	1.25267e-09 (rank : 59)	NC score	0.490744 (rank : 45)
Query Neighborhood Hits	458	Target Neighborhood Hits	456	Shared Neighborhood Hits	250
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

CNTN2_MOUSE
θ value	1.63604e-09 (rank : 60)	NC score	0.372772 (rank : 139)
Query Neighborhood Hits	458	Target Neighborhood Hits	450	Shared Neighborhood Hits	151
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

DLL1_HUMAN
θ value	1.63604e-09 (rank : 61)	NC score	0.492793 (rank : 44)
Query Neighborhood Hits	458	Target Neighborhood Hits	455	Shared Neighborhood Hits	253
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DSCL1_HUMAN
θ value	1.63604e-09 (rank : 62)	NC score	0.385131 (rank : 124)
Query Neighborhood Hits	458	Target Neighborhood Hits	589	Shared Neighborhood Hits	162
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

NOTC3_HUMAN
θ value	1.63604e-09 (rank : 63)	NC score	0.434367 (rank : 70)
Query Neighborhood Hits	458	Target Neighborhood Hits	1062	Shared Neighborhood Hits	266
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
θ value	1.63604e-09 (rank : 64)	NC score	0.419496 (rank : 85)
Query Neighborhood Hits	458	Target Neighborhood Hits	872	Shared Neighborhood Hits	264
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

DCC_HUMAN
θ value	2.13673e-09 (rank : 65)	NC score	0.395549 (rank : 108)
Query Neighborhood Hits	458	Target Neighborhood Hits	583	Shared Neighborhood Hits	163
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

STAB2_HUMAN
θ value	2.13673e-09 (rank : 66)	NC score	0.466185 (rank : 56)
Query Neighborhood Hits	458	Target Neighborhood Hits	534	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

DCC_MOUSE
θ value	2.79066e-09 (rank : 67)	NC score	0.385578 (rank : 123)
Query Neighborhood Hits	458	Target Neighborhood Hits	896	Shared Neighborhood Hits	173
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

MYOM2_HUMAN
θ value	3.64472e-09 (rank : 68)	NC score	0.376557 (rank : 131)
Query Neighborhood Hits	458	Target Neighborhood Hits	341	Shared Neighborhood Hits	134
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

NOTC3_MOUSE
θ value	3.64472e-09 (rank : 69)	NC score	0.432644 (rank : 73)
Query Neighborhood Hits	458	Target Neighborhood Hits	975	Shared Neighborhood Hits	267
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CNTN5_MOUSE
θ value	6.21693e-09 (rank : 70)	NC score	0.367410 (rank : 147)
Query Neighborhood Hits	458	Target Neighborhood Hits	434	Shared Neighborhood Hits	140
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

STAB2_MOUSE
θ value	6.21693e-09 (rank : 71)	NC score	0.473771 (rank : 53)
Query Neighborhood Hits	458	Target Neighborhood Hits	528	Shared Neighborhood Hits	263
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

EGFL9_MOUSE
θ value	8.11959e-09 (rank : 72)	NC score	0.503452 (rank : 40)
Query Neighborhood Hits	458	Target Neighborhood Hits	379	Shared Neighborhood Hits	239
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EPHB2_HUMAN
θ value	8.11959e-09 (rank : 73)	NC score	0.153570 (rank : 486)
Query Neighborhood Hits	458	Target Neighborhood Hits	983	Shared Neighborhood Hits	165
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	8.11959e-09 (rank : 74)	NC score	0.153494 (rank : 488)
Query Neighborhood Hits	458	Target Neighborhood Hits	982	Shared Neighborhood Hits	165
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

STAB1_HUMAN
θ value	8.11959e-09 (rank : 75)	NC score	0.466192 (rank : 55)
Query Neighborhood Hits	458	Target Neighborhood Hits	546	Shared Neighborhood Hits	258
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TIE1_HUMAN
θ value	8.11959e-09 (rank : 76)	NC score	0.276299 (rank : 249)
Query Neighborhood Hits	458	Target Neighborhood Hits	1241	Shared Neighborhood Hits	336
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CNTN1_MOUSE
θ value	1.38499e-08 (rank : 77)	NC score	0.365573 (rank : 151)
Query Neighborhood Hits	458	Target Neighborhood Hits	422	Shared Neighborhood Hits	138
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN2_HUMAN
θ value	1.38499e-08 (rank : 78)	NC score	0.374831 (rank : 135)
Query Neighborhood Hits	458	Target Neighborhood Hits	440	Shared Neighborhood Hits	151
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

NOTC2_MOUSE
θ value	1.38499e-08 (rank : 79)	NC score	0.427519 (rank : 78)
Query Neighborhood Hits	458	Target Neighborhood Hits	1069	Shared Neighborhood Hits	261
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

STAB1_MOUSE
θ value	1.38499e-08 (rank : 80)	NC score	0.469211 (rank : 54)
Query Neighborhood Hits	458	Target Neighborhood Hits	566	Shared Neighborhood Hits	261
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

ROBO3_HUMAN
θ value	1.80886e-08 (rank : 81)	NC score	0.336215 (rank : 172)
Query Neighborhood Hits	458	Target Neighborhood Hits	570	Shared Neighborhood Hits	146
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

CNTN5_HUMAN
θ value	2.36244e-08 (rank : 82)	NC score	0.370248 (rank : 142)
Query Neighborhood Hits	458	Target Neighborhood Hits	446	Shared Neighborhood Hits	149
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

PTPRK_MOUSE
θ value	2.36244e-08 (rank : 83)	NC score	0.230488 (rank : 309)
Query Neighborhood Hits	458	Target Neighborhood Hits	223	Shared Neighborhood Hits	120
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

CRUM1_MOUSE
θ value	4.0297e-08 (rank : 84)	NC score	0.465225 (rank : 57)
Query Neighborhood Hits	458	Target Neighborhood Hits	444	Shared Neighborhood Hits	235
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

EPHB4_HUMAN
θ value	4.0297e-08 (rank : 85)	NC score	0.167792 (rank : 440)
Query Neighborhood Hits	458	Target Neighborhood Hits	1056	Shared Neighborhood Hits	231
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

PTPRK_HUMAN
θ value	4.0297e-08 (rank : 86)	NC score	0.228055 (rank : 317)
Query Neighborhood Hits	458	Target Neighborhood Hits	228	Shared Neighborhood Hits	121
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

CNTN1_HUMAN
θ value	5.26297e-08 (rank : 87)	NC score	0.364277 (rank : 155)
Query Neighborhood Hits	458	Target Neighborhood Hits	431	Shared Neighborhood Hits	139
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

NFASC_HUMAN
θ value	5.26297e-08 (rank : 88)	NC score	0.386431 (rank : 122)
Query Neighborhood Hits	458	Target Neighborhood Hits	497	Shared Neighborhood Hits	154
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

SREC2_MOUSE
θ value	5.26297e-08 (rank : 89)	NC score	0.548027 (rank : 23)
Query Neighborhood Hits	458	Target Neighborhood Hits	605	Shared Neighborhood Hits	260
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

COCA1_MOUSE
θ value	6.87365e-08 (rank : 90)	NC score	0.315596 (rank : 203)
Query Neighborhood Hits	458	Target Neighborhood Hits	467	Shared Neighborhood Hits	146
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

LAMB3_MOUSE
θ value	6.87365e-08 (rank : 91)	NC score	0.406174 (rank : 95)
Query Neighborhood Hits	458	Target Neighborhood Hits	444	Shared Neighborhood Hits	195
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

SREC2_HUMAN
θ value	6.87365e-08 (rank : 92)	NC score	0.545720 (rank : 24)
Query Neighborhood Hits	458	Target Neighborhood Hits	645	Shared Neighborhood Hits	261
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC_HUMAN
θ value	6.87365e-08 (rank : 93)	NC score	0.524885 (rank : 30)
Query Neighborhood Hits	458	Target Neighborhood Hits	645	Shared Neighborhood Hits	266
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

USH2A_HUMAN
θ value	6.87365e-08 (rank : 94)	NC score	0.580530 (rank : 21)
Query Neighborhood Hits	458	Target Neighborhood Hits	600	Shared Neighborhood Hits	336
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

DLL3_HUMAN
θ value	8.97725e-08 (rank : 95)	NC score	0.497415 (rank : 41)
Query Neighborhood Hits	458	Target Neighborhood Hits	419	Shared Neighborhood Hits	236
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

EPHB4_MOUSE
θ value	8.97725e-08 (rank : 96)	NC score	0.161979 (rank : 456)
Query Neighborhood Hits	458	Target Neighborhood Hits	1013	Shared Neighborhood Hits	204
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

CRUM1_HUMAN
θ value	1.17247e-07 (rank : 97)	NC score	0.463590 (rank : 58)
Query Neighborhood Hits	458	Target Neighborhood Hits	457	Shared Neighborhood Hits	241
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FNDC3_MOUSE
θ value	1.17247e-07 (rank : 98)	NC score	0.451957 (rank : 62)
Query Neighborhood Hits	458	Target Neighborhood Hits	207	Shared Neighborhood Hits	147
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

EGFL9_HUMAN
θ value	1.53129e-07 (rank : 99)	NC score	0.504389 (rank : 38)
Query Neighborhood Hits	458	Target Neighborhood Hits	365	Shared Neighborhood Hits	235
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

USH2A_MOUSE
θ value	1.53129e-07 (rank : 100)	NC score	0.586001 (rank : 20)
Query Neighborhood Hits	458	Target Neighborhood Hits	626	Shared Neighborhood Hits	338
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

NAGPA_HUMAN
θ value	1.99992e-07 (rank : 101)	NC score	0.525735 (rank : 29)
Query Neighborhood Hits	458	Target Neighborhood Hits	282	Shared Neighborhood Hits	196
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ROBO2_HUMAN
θ value	1.99992e-07 (rank : 102)	NC score	0.334534 (rank : 173)
Query Neighborhood Hits	458	Target Neighborhood Hits	479	Shared Neighborhood Hits	143
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO3_MOUSE
θ value	1.99992e-07 (rank : 103)	NC score	0.330196 (rank : 178)
Query Neighborhood Hits	458	Target Neighborhood Hits	524	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

FINC_HUMAN
θ value	2.61198e-07 (rank : 104)	NC score	0.415584 (rank : 87)
Query Neighborhood Hits	458	Target Neighborhood Hits	302	Shared Neighborhood Hits	173
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

LAMA3_MOUSE
θ value	2.61198e-07 (rank : 105)	NC score	0.374265 (rank : 136)
Query Neighborhood Hits	458	Target Neighborhood Hits	859	Shared Neighborhood Hits	250
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LTBP2_HUMAN
θ value	2.61198e-07 (rank : 106)	NC score	0.393542 (rank : 112)
Query Neighborhood Hits	458	Target Neighborhood Hits	552	Shared Neighborhood Hits	262
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

DNER_MOUSE
θ value	3.41135e-07 (rank : 107)	NC score	0.476722 (rank : 50)
Query Neighborhood Hits	458	Target Neighborhood Hits	413	Shared Neighborhood Hits	236
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

FNDC3_HUMAN
θ value	3.41135e-07 (rank : 108)	NC score	0.450795 (rank : 63)
Query Neighborhood Hits	458	Target Neighborhood Hits	196	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ROBO2_MOUSE
θ value	3.41135e-07 (rank : 109)	NC score	0.333869 (rank : 175)
Query Neighborhood Hits	458	Target Neighborhood Hits	504	Shared Neighborhood Hits	146
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

DNER_HUMAN
θ value	5.81887e-07 (rank : 110)	NC score	0.474926 (rank : 51)
Query Neighborhood Hits	458	Target Neighborhood Hits	460	Shared Neighborhood Hits	239
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

GPR98_HUMAN
θ value	7.59969e-07 (rank : 111)	NC score	0.105599 (rank : 653)
Query Neighborhood Hits	458	Target Neighborhood Hits	202	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

ROS_HUMAN
θ value	7.59969e-07 (rank : 112)	NC score	0.133340 (rank : 532)
Query Neighborhood Hits	458	Target Neighborhood Hits	907	Shared Neighborhood Hits	151
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

LAMC3_MOUSE
θ value	9.92553e-07 (rank : 113)	NC score	0.406330 (rank : 94)
Query Neighborhood Hits	458	Target Neighborhood Hits	624	Shared Neighborhood Hits	236
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

NAGPA_MOUSE
θ value	9.92553e-07 (rank : 114)	NC score	0.508684 (rank : 34)
Query Neighborhood Hits	458	Target Neighborhood Hits	308	Shared Neighborhood Hits	202
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

FBN2_HUMAN
θ value	1.29631e-06 (rank : 115)	NC score	0.403630 (rank : 98)
Query Neighborhood Hits	458	Target Neighborhood Hits	560	Shared Neighborhood Hits	262
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

CNTN6_MOUSE
θ value	1.69304e-06 (rank : 116)	NC score	0.356780 (rank : 163)
Query Neighborhood Hits	458	Target Neighborhood Hits	429	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

COCA1_HUMAN
θ value	1.69304e-06 (rank : 117)	NC score	0.307226 (rank : 208)
Query Neighborhood Hits	458	Target Neighborhood Hits	458	Shared Neighborhood Hits	142
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

LAMB2_HUMAN
θ value	1.69304e-06 (rank : 118)	NC score	0.425278 (rank : 82)
Query Neighborhood Hits	458	Target Neighborhood Hits	692	Shared Neighborhood Hits	239
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB3_HUMAN
θ value	1.69304e-06 (rank : 119)	NC score	0.396534 (rank : 105)
Query Neighborhood Hits	458	Target Neighborhood Hits	461	Shared Neighborhood Hits	179
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

NAC3_HUMAN
θ value	1.69304e-06 (rank : 120)	NC score	0.114626 (rank : 593)
Query Neighborhood Hits	458	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	P57103, Q8IUE9, Q8IUF0, Q8NFI7	Gene names	SLC8A3, NCX3
Domain Architecture
Description	Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3).

PTPRU_HUMAN
θ value	1.69304e-06 (rank : 121)	NC score	0.245559 (rank : 287)
Query Neighborhood Hits	458	Target Neighborhood Hits	237	Shared Neighborhood Hits	128
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

FINC_MOUSE
θ value	2.21117e-06 (rank : 122)	NC score	0.416168 (rank : 86)
Query Neighborhood Hits	458	Target Neighborhood Hits	309	Shared Neighborhood Hits	171
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MYOM1_MOUSE
θ value	2.21117e-06 (rank : 123)	NC score	0.366960 (rank : 148)
Query Neighborhood Hits	458	Target Neighborhood Hits	415	Shared Neighborhood Hits	152
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

COKA1_HUMAN
θ value	2.88788e-06 (rank : 124)	NC score	0.249166 (rank : 281)
Query Neighborhood Hits	458	Target Neighborhood Hits	403	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

LAMA5_MOUSE
θ value	3.77169e-06 (rank : 125)	NC score	0.439008 (rank : 67)
Query Neighborhood Hits	458	Target Neighborhood Hits	828	Shared Neighborhood Hits	270
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EPHA3_MOUSE
θ value	4.92598e-06 (rank : 126)	NC score	0.160661 (rank : 462)
Query Neighborhood Hits	458	Target Neighborhood Hits	1009	Shared Neighborhood Hits	194
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA5_HUMAN
θ value	6.43352e-06 (rank : 127)	NC score	0.151737 (rank : 491)
Query Neighborhood Hits	458	Target Neighborhood Hits	1009	Shared Neighborhood Hits	175
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

FREM2_MOUSE
θ value	6.43352e-06 (rank : 128)	NC score	0.096815 (rank : 686)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

LAMA1_MOUSE
θ value	6.43352e-06 (rank : 129)	NC score	0.408077 (rank : 91)
Query Neighborhood Hits	458	Target Neighborhood Hits	838	Shared Neighborhood Hits	262
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA5_HUMAN
θ value	6.43352e-06 (rank : 130)	NC score	0.432976 (rank : 71)
Query Neighborhood Hits	458	Target Neighborhood Hits	976	Shared Neighborhood Hits	267
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

COEA1_HUMAN
θ value	8.40245e-06 (rank : 131)	NC score	0.249046 (rank : 282)
Query Neighborhood Hits	458	Target Neighborhood Hits	427	Shared Neighborhood Hits	125
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

EPHA3_HUMAN
θ value	8.40245e-06 (rank : 132)	NC score	0.156362 (rank : 480)
Query Neighborhood Hits	458	Target Neighborhood Hits	1005	Shared Neighborhood Hits	192
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

LAMA1_HUMAN
θ value	1.09739e-05 (rank : 133)	NC score	0.412203 (rank : 88)
Query Neighborhood Hits	458	Target Neighborhood Hits	804	Shared Neighborhood Hits	258
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LTBP2_MOUSE
θ value	1.09739e-05 (rank : 134)	NC score	0.396482 (rank : 106)
Query Neighborhood Hits	458	Target Neighborhood Hits	617	Shared Neighborhood Hits	256
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

GPR98_MOUSE
θ value	1.43324e-05 (rank : 135)	NC score	0.103601 (rank : 659)
Query Neighborhood Hits	458	Target Neighborhood Hits	206	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

LAMB1_MOUSE
θ value	1.43324e-05 (rank : 136)	NC score	0.407407 (rank : 92)
Query Neighborhood Hits	458	Target Neighborhood Hits	919	Shared Neighborhood Hits	227
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

PTPRM_MOUSE
θ value	1.43324e-05 (rank : 137)	NC score	0.259511 (rank : 268)
Query Neighborhood Hits	458	Target Neighborhood Hits	238	Shared Neighborhood Hits	129
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

CNTN6_HUMAN
θ value	1.87187e-05 (rank : 138)	NC score	0.361918 (rank : 157)
Query Neighborhood Hits	458	Target Neighborhood Hits	422	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

DUET_HUMAN
θ value	1.87187e-05 (rank : 139)	NC score	0.111061 (rank : 613)
Query Neighborhood Hits	458	Target Neighborhood Hits	1220	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

FBN2_MOUSE
θ value	1.87187e-05 (rank : 140)	NC score	0.393772 (rank : 111)
Query Neighborhood Hits	458	Target Neighborhood Hits	549	Shared Neighborhood Hits	261
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

SLIT3_HUMAN
θ value	1.87187e-05 (rank : 141)	NC score	0.311222 (rank : 206)
Query Neighborhood Hits	458	Target Neighborhood Hits	682	Shared Neighborhood Hits	232
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

COEA1_MOUSE
θ value	2.44474e-05 (rank : 142)	NC score	0.272001 (rank : 255)
Query Neighborhood Hits	458	Target Neighborhood Hits	402	Shared Neighborhood Hits	110
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CRUM2_HUMAN
θ value	2.44474e-05 (rank : 143)	NC score	0.462396 (rank : 59)
Query Neighborhood Hits	458	Target Neighborhood Hits	453	Shared Neighborhood Hits	242
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FBN1_HUMAN
θ value	2.44474e-05 (rank : 144)	NC score	0.393897 (rank : 110)
Query Neighborhood Hits	458	Target Neighborhood Hits	557	Shared Neighborhood Hits	259
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LAMB1_HUMAN
θ value	2.44474e-05 (rank : 145)	NC score	0.388198 (rank : 120)
Query Neighborhood Hits	458	Target Neighborhood Hits	1018	Shared Neighborhood Hits	234
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_MOUSE
θ value	2.44474e-05 (rank : 146)	NC score	0.425179 (rank : 83)
Query Neighborhood Hits	458	Target Neighborhood Hits	722	Shared Neighborhood Hits	236
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LTBP4_MOUSE
θ value	2.44474e-05 (rank : 147)	NC score	0.394690 (rank : 109)
Query Neighborhood Hits	458	Target Neighborhood Hits	607	Shared Neighborhood Hits	253
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

PTPRM_HUMAN
θ value	2.44474e-05 (rank : 148)	NC score	0.259898 (rank : 266)
Query Neighborhood Hits	458	Target Neighborhood Hits	244	Shared Neighborhood Hits	128
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

SLIT3_MOUSE
θ value	3.19293e-05 (rank : 149)	NC score	0.317024 (rank : 200)
Query Neighborhood Hits	458	Target Neighborhood Hits	700	Shared Neighborhood Hits	239
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

EPHA7_MOUSE
θ value	4.1701e-05 (rank : 150)	NC score	0.162976 (rank : 453)
Query Neighborhood Hits	458	Target Neighborhood Hits	1025	Shared Neighborhood Hits	190
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

FBN1_MOUSE
θ value	4.1701e-05 (rank : 151)	NC score	0.396636 (rank : 104)
Query Neighborhood Hits	458	Target Neighborhood Hits	563	Shared Neighborhood Hits	261
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

MEGF9_MOUSE
θ value	4.1701e-05 (rank : 152)	NC score	0.430115 (rank : 75)
Query Neighborhood Hits	458	Target Neighborhood Hits	896	Shared Neighborhood Hits	231
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

GAS6_MOUSE
θ value	5.44631e-05 (rank : 153)	NC score	0.329135 (rank : 182)
Query Neighborhood Hits	458	Target Neighborhood Hits	343	Shared Neighborhood Hits	209
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

LAMA2_HUMAN
θ value	5.44631e-05 (rank : 154)	NC score	0.383680 (rank : 126)
Query Neighborhood Hits	458	Target Neighborhood Hits	1092	Shared Neighborhood Hits	255
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC3_HUMAN
θ value	5.44631e-05 (rank : 155)	NC score	0.397805 (rank : 100)
Query Neighborhood Hits	458	Target Neighborhood Hits	588	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

ROBO1_MOUSE
θ value	5.44631e-05 (rank : 156)	NC score	0.325645 (rank : 187)
Query Neighborhood Hits	458	Target Neighborhood Hits	559	Shared Neighborhood Hits	149
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

DLL3_MOUSE
θ value	7.1131e-05 (rank : 157)	NC score	0.489052 (rank : 46)
Query Neighborhood Hits	458	Target Neighborhood Hits	399	Shared Neighborhood Hits	240
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

ANKF1_HUMAN
θ value	9.29e-05 (rank : 158)	NC score	0.158115 (rank : 471)
Query Neighborhood Hits	458	Target Neighborhood Hits	126	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

EPHB3_HUMAN
θ value	9.29e-05 (rank : 159)	NC score	0.157187 (rank : 473)
Query Neighborhood Hits	458	Target Neighborhood Hits	996	Shared Neighborhood Hits	173
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

NAC1_HUMAN
θ value	9.29e-05 (rank : 160)	NC score	0.109424 (rank : 622)
Query Neighborhood Hits	458	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	P32418, O95849, Q9UBL8, Q9UDN1, Q9UDN2, Q9UKX6	Gene names	SLC8A1, CNC, NCX1
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

EPHA7_HUMAN
θ value	0.000121331 (rank : 161)	NC score	0.167878 (rank : 439)
Query Neighborhood Hits	458	Target Neighborhood Hits	1053	Shared Neighborhood Hits	214
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHB3_MOUSE
θ value	0.000121331 (rank : 162)	NC score	0.156946 (rank : 476)
Query Neighborhood Hits	458	Target Neighborhood Hits	996	Shared Neighborhood Hits	163
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

FREM2_HUMAN
θ value	0.000121331 (rank : 163)	NC score	0.093579 (rank : 709)
Query Neighborhood Hits	458	Target Neighborhood Hits	76	Shared Neighborhood Hits	18
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

PUNC_HUMAN
θ value	0.000121331 (rank : 164)	NC score	0.332776 (rank : 177)
Query Neighborhood Hits	458	Target Neighborhood Hits	449	Shared Neighborhood Hits	137
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

EPHA8_MOUSE
θ value	0.000158464 (rank : 165)	NC score	0.156273 (rank : 481)
Query Neighborhood Hits	458	Target Neighborhood Hits	969	Shared Neighborhood Hits	154
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

FREM3_HUMAN
θ value	0.000158464 (rank : 166)	NC score	0.092849 (rank : 714)
Query Neighborhood Hits	458	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

LAMC1_MOUSE
θ value	0.000158464 (rank : 167)	NC score	0.388166 (rank : 121)
Query Neighborhood Hits	458	Target Neighborhood Hits	856	Shared Neighborhood Hits	240
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NAC2_HUMAN
θ value	0.000158464 (rank : 168)	NC score	0.106715 (rank : 642)
Query Neighborhood Hits	458	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPR5	Gene names	SLC8A2, KIAA1087, NCX2
Domain Architecture
Description	Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2).

FBN3_HUMAN
θ value	0.00020696 (rank : 169)	NC score	0.397899 (rank : 99)
Query Neighborhood Hits	458	Target Neighborhood Hits	543	Shared Neighborhood Hits	253
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LAMA2_MOUSE
θ value	0.00020696 (rank : 170)	NC score	0.368631 (rank : 143)
Query Neighborhood Hits	458	Target Neighborhood Hits	1198	Shared Neighborhood Hits	257
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_HUMAN
θ value	0.00020696 (rank : 171)	NC score	0.370419 (rank : 141)
Query Neighborhood Hits	458	Target Neighborhood Hits	922	Shared Neighborhood Hits	237
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LTBP3_MOUSE
θ value	0.00020696 (rank : 172)	NC score	0.363952 (rank : 156)
Query Neighborhood Hits	458	Target Neighborhood Hits	475	Shared Neighborhood Hits	244
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MYPC3_MOUSE
θ value	0.00020696 (rank : 173)	NC score	0.281625 (rank : 241)
Query Neighborhood Hits	458	Target Neighborhood Hits	310	Shared Neighborhood Hits	125
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NAC1_MOUSE
θ value	0.00020696 (rank : 174)	NC score	0.108031 (rank : 635)
Query Neighborhood Hits	458	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	P70414	Gene names	Slc8a1, Ncx
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

WIF1_HUMAN
θ value	0.00020696 (rank : 175)	NC score	0.536133 (rank : 25)
Query Neighborhood Hits	458	Target Neighborhood Hits	392	Shared Neighborhood Hits	234
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

EPHA4_HUMAN
θ value	0.000270298 (rank : 176)	NC score	0.155252 (rank : 484)
Query Neighborhood Hits	458	Target Neighborhood Hits	975	Shared Neighborhood Hits	160
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHB6_HUMAN
θ value	0.000270298 (rank : 177)	NC score	0.182830 (rank : 392)
Query Neighborhood Hits	458	Target Neighborhood Hits	912	Shared Neighborhood Hits	180
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

INSRR_HUMAN
θ value	0.000270298 (rank : 178)	NC score	0.128635 (rank : 545)
Query Neighborhood Hits	458	Target Neighborhood Hits	950	Shared Neighborhood Hits	164
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	0.000270298 (rank : 179)	NC score	0.126938 (rank : 550)
Query Neighborhood Hits	458	Target Neighborhood Hits	961	Shared Neighborhood Hits	172
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LTBP3_HUMAN
θ value	0.000270298 (rank : 180)	NC score	0.367666 (rank : 146)
Query Neighborhood Hits	458	Target Neighborhood Hits	502	Shared Neighborhood Hits	241
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NFASC_MOUSE
θ value	0.000270298 (rank : 181)	NC score	0.364360 (rank : 154)
Query Neighborhood Hits	458	Target Neighborhood Hits	475	Shared Neighborhood Hits	146
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

EPHA4_MOUSE
θ value	0.00035302 (rank : 182)	NC score	0.157064 (rank : 474)
Query Neighborhood Hits	458	Target Neighborhood Hits	982	Shared Neighborhood Hits	168
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA5_MOUSE
θ value	0.00035302 (rank : 183)	NC score	0.128031 (rank : 547)
Query Neighborhood Hits	458	Target Neighborhood Hits	950	Shared Neighborhood Hits	137
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

MYPC3_HUMAN
θ value	0.00035302 (rank : 184)	NC score	0.285898 (rank : 232)
Query Neighborhood Hits	458	Target Neighborhood Hits	318	Shared Neighborhood Hits	125
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

PTPRT_HUMAN
θ value	0.00035302 (rank : 185)	NC score	0.246009 (rank : 286)
Query Neighborhood Hits	458	Target Neighborhood Hits	217	Shared Neighborhood Hits	120
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	0.00035302 (rank : 186)	NC score	0.246289 (rank : 284)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	120
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PUNC_MOUSE
θ value	0.000461057 (rank : 187)	NC score	0.327611 (rank : 186)
Query Neighborhood Hits	458	Target Neighborhood Hits	501	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

FREM3_MOUSE
θ value	0.000602161 (rank : 188)	NC score	0.092093 (rank : 718)
Query Neighborhood Hits	458	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

ROBO1_HUMAN
θ value	0.000602161 (rank : 189)	NC score	0.320776 (rank : 193)
Query Neighborhood Hits	458	Target Neighborhood Hits	529	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

WIF1_MOUSE
θ value	0.000602161 (rank : 190)	NC score	0.535171 (rank : 26)
Query Neighborhood Hits	458	Target Neighborhood Hits	393	Shared Neighborhood Hits	234
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CDON_HUMAN
θ value	0.000786445 (rank : 191)	NC score	0.305612 (rank : 211)
Query Neighborhood Hits	458	Target Neighborhood Hits	412	Shared Neighborhood Hits	125
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CUBN_HUMAN
θ value	0.000786445 (rank : 192)	NC score	0.340448 (rank : 169)
Query Neighborhood Hits	458	Target Neighborhood Hits	482	Shared Neighborhood Hits	230
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

PGBM_MOUSE
θ value	0.000786445 (rank : 193)	NC score	0.430017 (rank : 76)
Query Neighborhood Hits	458	Target Neighborhood Hits	1073	Shared Neighborhood Hits	335
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PTPRV_MOUSE
θ value	0.000786445 (rank : 194)	NC score	0.188883 (rank : 383)
Query Neighborhood Hits	458	Target Neighborhood Hits	179	Shared Neighborhood Hits	76
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

SLIT2_HUMAN
θ value	0.000786445 (rank : 195)	NC score	0.322564 (rank : 190)
Query Neighborhood Hits	458	Target Neighborhood Hits	708	Shared Neighborhood Hits	237
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LRP1_HUMAN
θ value	0.00102713 (rank : 196)	NC score	0.329811 (rank : 180)
Query Neighborhood Hits	458	Target Neighborhood Hits	617	Shared Neighborhood Hits	263
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LTB1L_MOUSE
θ value	0.00102713 (rank : 197)	NC score	0.364839 (rank : 152)
Query Neighborhood Hits	458	Target Neighborhood Hits	514	Shared Neighborhood Hits	239
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.00102713 (rank : 198)	NC score	0.364493 (rank : 153)
Query Neighborhood Hits	458	Target Neighborhood Hits	479	Shared Neighborhood Hits	231
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

UFO_MOUSE
θ value	0.00102713 (rank : 199)	NC score	0.140823 (rank : 515)
Query Neighborhood Hits	458	Target Neighborhood Hits	988	Shared Neighborhood Hits	140
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

CELR3_HUMAN
θ value	0.00134147 (rank : 200)	NC score	0.218993 (rank : 335)
Query Neighborhood Hits	458	Target Neighborhood Hits	680	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

LRP1B_MOUSE
θ value	0.00134147 (rank : 201)	NC score	0.321310 (rank : 191)
Query Neighborhood Hits	458	Target Neighborhood Hits	606	Shared Neighborhood Hits	257
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

CDON_MOUSE
θ value	0.00175202 (rank : 202)	NC score	0.303790 (rank : 213)
Query Neighborhood Hits	458	Target Neighborhood Hits	410	Shared Neighborhood Hits	123
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

LRP1B_HUMAN
θ value	0.00175202 (rank : 203)	NC score	0.325086 (rank : 189)
Query Neighborhood Hits	458	Target Neighborhood Hits	602	Shared Neighborhood Hits	258
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MEGF9_HUMAN
θ value	0.00175202 (rank : 204)	NC score	0.450448 (rank : 64)
Query Neighborhood Hits	458	Target Neighborhood Hits	557	Shared Neighborhood Hits	238
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SLIT1_HUMAN
θ value	0.00175202 (rank : 205)	NC score	0.333032 (rank : 176)
Query Neighborhood Hits	458	Target Neighborhood Hits	700	Shared Neighborhood Hits	234
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	0.00175202 (rank : 206)	NC score	0.334379 (rank : 174)
Query Neighborhood Hits	458	Target Neighborhood Hits	715	Shared Neighborhood Hits	236
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_MOUSE
θ value	0.00175202 (rank : 207)	NC score	0.317753 (rank : 199)
Query Neighborhood Hits	458	Target Neighborhood Hits	684	Shared Neighborhood Hits	234
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ATRN_MOUSE
θ value	0.00228821 (rank : 208)	NC score	0.327990 (rank : 185)
Query Neighborhood Hits	458	Target Neighborhood Hits	519	Shared Neighborhood Hits	215
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BOC_HUMAN
θ value	0.00228821 (rank : 209)	NC score	0.303616 (rank : 214)
Query Neighborhood Hits	458	Target Neighborhood Hits	543	Shared Neighborhood Hits	133
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CSPG3_HUMAN
θ value	0.00228821 (rank : 210)	NC score	0.252152 (rank : 276)
Query Neighborhood Hits	458	Target Neighborhood Hits	676	Shared Neighborhood Hits	208
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FBLN2_HUMAN
θ value	0.00228821 (rank : 211)	NC score	0.328370 (rank : 184)
Query Neighborhood Hits	458	Target Neighborhood Hits	392	Shared Neighborhood Hits	194
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

BOC_MOUSE
θ value	0.00298849 (rank : 212)	NC score	0.298100 (rank : 220)
Query Neighborhood Hits	458	Target Neighborhood Hits	433	Shared Neighborhood Hits	123
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

EPHA8_HUMAN
θ value	0.00298849 (rank : 213)	NC score	0.153117 (rank : 489)
Query Neighborhood Hits	458	Target Neighborhood Hits	956	Shared Neighborhood Hits	152
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHB6_MOUSE
θ value	0.00298849 (rank : 214)	NC score	0.173904 (rank : 423)
Query Neighborhood Hits	458	Target Neighborhood Hits	906	Shared Neighborhood Hits	161
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FRAS1_HUMAN
θ value	0.00298849 (rank : 215)	NC score	0.301339 (rank : 216)
Query Neighborhood Hits	458	Target Neighborhood Hits	759	Shared Neighborhood Hits	233
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMC2_MOUSE
θ value	0.00298849 (rank : 216)	NC score	0.393502 (rank : 113)
Query Neighborhood Hits	458	Target Neighborhood Hits	614	Shared Neighborhood Hits	242
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

NTNG1_HUMAN
θ value	0.00298849 (rank : 217)	NC score	0.336876 (rank : 171)
Query Neighborhood Hits	458	Target Neighborhood Hits	247	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PGBM_HUMAN
θ value	0.00298849 (rank : 218)	NC score	0.427877 (rank : 77)
Query Neighborhood Hits	458	Target Neighborhood Hits	1113	Shared Neighborhood Hits	338
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CUBN_MOUSE
θ value	0.00390308 (rank : 219)	NC score	0.351798 (rank : 165)
Query Neighborhood Hits	458	Target Neighborhood Hits	477	Shared Neighborhood Hits	226
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

NELL2_HUMAN
θ value	0.00390308 (rank : 220)	NC score	0.396092 (rank : 107)
Query Neighborhood Hits	458	Target Neighborhood Hits	449	Shared Neighborhood Hits	246
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

TIE2_HUMAN
θ value	0.00390308 (rank : 221)	NC score	0.256440 (rank : 269)
Query Neighborhood Hits	458	Target Neighborhood Hits	1192	Shared Neighborhood Hits	329
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

CD45_MOUSE
θ value	0.00665767 (rank : 222)	NC score	0.127779 (rank : 549)
Query Neighborhood Hits	458	Target Neighborhood Hits	178	Shared Neighborhood Hits	51
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

EPHA2_HUMAN
θ value	0.00665767 (rank : 223)	NC score	0.143147 (rank : 510)
Query Neighborhood Hits	458	Target Neighborhood Hits	1021	Shared Neighborhood Hits	179
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

SORL_MOUSE
θ value	0.00665767 (rank : 224)	NC score	0.320244 (rank : 195)
Query Neighborhood Hits	458	Target Neighborhood Hits	439	Shared Neighborhood Hits	278
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

ATRN_HUMAN
θ value	0.00869519 (rank : 225)	NC score	0.328476 (rank : 183)
Query Neighborhood Hits	458	Target Neighborhood Hits	525	Shared Neighborhood Hits	221
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

FBLN5_MOUSE
θ value	0.00869519 (rank : 226)	NC score	0.280881 (rank : 242)
Query Neighborhood Hits	458	Target Neighborhood Hits	317	Shared Neighborhood Hits	191
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FRAS1_MOUSE
θ value	0.00869519 (rank : 227)	NC score	0.295876 (rank : 221)
Query Neighborhood Hits	458	Target Neighborhood Hits	747	Shared Neighborhood Hits	227
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

HCFC2_MOUSE
θ value	0.00869519 (rank : 228)	NC score	0.228679 (rank : 315)
Query Neighborhood Hits	458	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

CO7A1_HUMAN
θ value	0.0113563 (rank : 229)	NC score	0.222159 (rank : 329)
Query Neighborhood Hits	458	Target Neighborhood Hits	807	Shared Neighborhood Hits	152
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CREL1_MOUSE
θ value	0.0113563 (rank : 230)	NC score	0.355256 (rank : 164)
Query Neighborhood Hits	458	Target Neighborhood Hits	524	Shared Neighborhood Hits	211
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EPHA2_MOUSE
θ value	0.0113563 (rank : 231)	NC score	0.139463 (rank : 520)
Query Neighborhood Hits	458	Target Neighborhood Hits	1020	Shared Neighborhood Hits	182
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

ADA19_MOUSE
θ value	0.0148317 (rank : 232)	NC score	0.110029 (rank : 619)
Query Neighborhood Hits	458	Target Neighborhood Hits	315	Shared Neighborhood Hits	167
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

AGRIN_HUMAN
θ value	0.0148317 (rank : 233)	NC score	0.405590 (rank : 96)
Query Neighborhood Hits	458	Target Neighborhood Hits	582	Shared Neighborhood Hits	251
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FBLN2_MOUSE
θ value	0.0148317 (rank : 234)	NC score	0.317006 (rank : 201)
Query Neighborhood Hits	458	Target Neighborhood Hits	505	Shared Neighborhood Hits	207
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LAMC2_HUMAN
θ value	0.0148317 (rank : 235)	NC score	0.366445 (rank : 150)
Query Neighborhood Hits	458	Target Neighborhood Hits	715	Shared Neighborhood Hits	234
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

NTNG1_MOUSE
θ value	0.0148317 (rank : 236)	NC score	0.341750 (rank : 168)
Query Neighborhood Hits	458	Target Neighborhood Hits	246	Shared Neighborhood Hits	179
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

CSPG3_MOUSE
θ value	0.0193708 (rank : 237)	NC score	0.253392 (rank : 273)
Query Neighborhood Hits	458	Target Neighborhood Hits	657	Shared Neighborhood Hits	211
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

IGF1R_HUMAN
θ value	0.0193708 (rank : 238)	NC score	0.113434 (rank : 599)
Query Neighborhood Hits	458	Target Neighborhood Hits	977	Shared Neighborhood Hits	153
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	0.0193708 (rank : 239)	NC score	0.113793 (rank : 596)
Query Neighborhood Hits	458	Target Neighborhood Hits	973	Shared Neighborhood Hits	158
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSR_MOUSE
θ value	0.0193708 (rank : 240)	NC score	0.114598 (rank : 594)
Query Neighborhood Hits	458	Target Neighborhood Hits	968	Shared Neighborhood Hits	146
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

PTPRZ_HUMAN
θ value	0.0193708 (rank : 241)	NC score	0.112357 (rank : 607)
Query Neighborhood Hits	458	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

COMP_MOUSE
θ value	0.0252991 (rank : 242)	NC score	0.282085 (rank : 239)
Query Neighborhood Hits	458	Target Neighborhood Hits	290	Shared Neighborhood Hits	197
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	0.0252991 (rank : 243)	NC score	0.373268 (rank : 138)
Query Neighborhood Hits	458	Target Neighborhood Hits	441	Shared Neighborhood Hits	206
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	0.0252991 (rank : 244)	NC score	0.246206 (rank : 285)
Query Neighborhood Hits	458	Target Neighborhood Hits	362	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

IL6RA_MOUSE
θ value	0.0252991 (rank : 245)	NC score	0.077100 (rank : 811)
Query Neighborhood Hits	458	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

RELN_HUMAN
θ value	0.0252991 (rank : 246)	NC score	0.249235 (rank : 280)
Query Neighborhood Hits	458	Target Neighborhood Hits	233	Shared Neighborhood Hits	157
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	0.0252991 (rank : 247)	NC score	0.251121 (rank : 277)
Query Neighborhood Hits	458	Target Neighborhood Hits	235	Shared Neighborhood Hits	158
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

CELR2_HUMAN
θ value	0.0330416 (rank : 248)	NC score	0.218317 (rank : 336)
Query Neighborhood Hits	458	Target Neighborhood Hits	657	Shared Neighborhood Hits	231
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

EPHA6_MOUSE
θ value	0.0330416 (rank : 249)	NC score	0.139575 (rank : 518)
Query Neighborhood Hits	458	Target Neighborhood Hits	946	Shared Neighborhood Hits	143
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

FBLN5_HUMAN
θ value	0.0330416 (rank : 250)	NC score	0.282646 (rank : 237)
Query Neighborhood Hits	458	Target Neighborhood Hits	329	Shared Neighborhood Hits	193
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

MYBPH_MOUSE
θ value	0.0330416 (rank : 251)	NC score	0.230519 (rank : 308)
Query Neighborhood Hits	458	Target Neighborhood Hits	290	Shared Neighborhood Hits	108
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NELL2_MOUSE
θ value	0.0330416 (rank : 252)	NC score	0.391867 (rank : 116)
Query Neighborhood Hits	458	Target Neighborhood Hits	436	Shared Neighborhood Hits	247
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

PTPRB_HUMAN
θ value	0.0330416 (rank : 253)	NC score	0.209883 (rank : 350)
Query Neighborhood Hits	458	Target Neighborhood Hits	242	Shared Neighborhood Hits	101
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

EPHA6_HUMAN
θ value	0.0431538 (rank : 254)	NC score	0.145392 (rank : 507)
Query Neighborhood Hits	458	Target Neighborhood Hits	959	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB1_HUMAN
θ value	0.0431538 (rank : 255)	NC score	0.148432 (rank : 502)
Query Neighborhood Hits	458	Target Neighborhood Hits	988	Shared Neighborhood Hits	173
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

HCFC1_HUMAN
θ value	0.0431538 (rank : 256)	NC score	0.099800 (rank : 672)
Query Neighborhood Hits	458	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC2_HUMAN
θ value	0.0431538 (rank : 257)	NC score	0.159858 (rank : 464)
Query Neighborhood Hits	458	Target Neighborhood Hits	154	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

INSR_HUMAN
θ value	0.0431538 (rank : 258)	NC score	0.112999 (rank : 602)
Query Neighborhood Hits	458	Target Neighborhood Hits	963	Shared Neighborhood Hits	148
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

NID1_MOUSE
θ value	0.0431538 (rank : 259)	NC score	0.273674 (rank : 252)
Query Neighborhood Hits	458	Target Neighborhood Hits	335	Shared Neighborhood Hits	189
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PP16A_MOUSE
θ value	0.0431538 (rank : 260)	NC score	0.029293 (rank : 1078)
Query Neighborhood Hits	458	Target Neighborhood Hits	318	Shared Neighborhood Hits	11
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

PROS_MOUSE
θ value	0.0431538 (rank : 261)	NC score	0.315412 (rank : 204)
Query Neighborhood Hits	458	Target Neighborhood Hits	330	Shared Neighborhood Hits	206
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

ADA19_HUMAN
θ value	0.0563607 (rank : 262)	NC score	0.104776 (rank : 657)
Query Neighborhood Hits	458	Target Neighborhood Hits	381	Shared Neighborhood Hits	155
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

CELR3_MOUSE
θ value	0.0563607 (rank : 263)	NC score	0.213264 (rank : 343)
Query Neighborhood Hits	458	Target Neighborhood Hits	687	Shared Neighborhood Hits	232
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

EDIL3_MOUSE
θ value	0.0563607 (rank : 264)	NC score	0.305745 (rank : 210)
Query Neighborhood Hits	458	Target Neighborhood Hits	317	Shared Neighborhood Hits	199
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

KRA51_HUMAN
θ value	0.0563607 (rank : 265)	NC score	0.534330 (rank : 27)
Query Neighborhood Hits	458	Target Neighborhood Hits	288	Shared Neighborhood Hits	168
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LEPR_HUMAN
θ value	0.0563607 (rank : 266)	NC score	0.077619 (rank : 808)
Query Neighborhood Hits	458	Target Neighborhood Hits	112	Shared Neighborhood Hits	57
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

ROBO4_HUMAN
θ value	0.0563607 (rank : 267)	NC score	0.279990 (rank : 244)
Query Neighborhood Hits	458	Target Neighborhood Hits	364	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

UFO_HUMAN
θ value	0.0563607 (rank : 268)	NC score	0.137387 (rank : 523)
Query Neighborhood Hits	458	Target Neighborhood Hits	981	Shared Neighborhood Hits	145
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

ADA17_HUMAN
θ value	0.0736092 (rank : 269)	NC score	0.115026 (rank : 592)
Query Neighborhood Hits	458	Target Neighborhood Hits	223	Shared Neighborhood Hits	98
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

DNJA1_HUMAN
θ value	0.0736092 (rank : 270)	NC score	0.014040 (rank : 1094)
Query Neighborhood Hits	458	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	P31689	Gene names	DNAJA1, DNAJ2, HDJ2, HSJ2, HSPF4
Domain Architecture
Description	DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2) (HSDJ).

DNJA1_MOUSE
θ value	0.0736092 (rank : 271)	NC score	0.014160 (rank : 1093)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	P63037, P54102	Gene names	Dnaja1, Dnaj2, Hsj2, Hspf4
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2).

GAS6_HUMAN
θ value	0.0736092 (rank : 272)	NC score	0.329260 (rank : 181)
Query Neighborhood Hits	458	Target Neighborhood Hits	348	Shared Neighborhood Hits	208
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

HHIP_MOUSE
θ value	0.0736092 (rank : 273)	NC score	0.370638 (rank : 140)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	176
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA58_HUMAN
θ value	0.0736092 (rank : 274)	NC score	0.511732 (rank : 33)
Query Neighborhood Hits	458	Target Neighborhood Hits	324	Shared Neighborhood Hits	182
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ROBO4_MOUSE
θ value	0.0736092 (rank : 275)	NC score	0.280635 (rank : 243)
Query Neighborhood Hits	458	Target Neighborhood Hits	358	Shared Neighborhood Hits	98
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SORL_HUMAN
θ value	0.0736092 (rank : 276)	NC score	0.311419 (rank : 205)
Query Neighborhood Hits	458	Target Neighborhood Hits	440	Shared Neighborhood Hits	271
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TSP4_MOUSE
θ value	0.0736092 (rank : 277)	NC score	0.301084 (rank : 217)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	189
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

ADA28_MOUSE
θ value	0.0961366 (rank : 278)	NC score	0.098713 (rank : 675)
Query Neighborhood Hits	458	Target Neighborhood Hits	241	Shared Neighborhood Hits	122
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

EGFL8_MOUSE
θ value	0.0961366 (rank : 279)	NC score	0.295335 (rank : 222)
Query Neighborhood Hits	458	Target Neighborhood Hits	266	Shared Neighborhood Hits	170
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

HCFC1_MOUSE
θ value	0.0961366 (rank : 280)	NC score	0.112743 (rank : 605)
Query Neighborhood Hits	458	Target Neighborhood Hits	348	Shared Neighborhood Hits	74
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HHIP_HUMAN
θ value	0.0961366 (rank : 281)	NC score	0.375264 (rank : 134)
Query Neighborhood Hits	458	Target Neighborhood Hits	249	Shared Neighborhood Hits	181
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LAMA3_HUMAN
θ value	0.0961366 (rank : 282)	NC score	0.306951 (rank : 209)
Query Neighborhood Hits	458	Target Neighborhood Hits	760	Shared Neighborhood Hits	218
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LTB1L_HUMAN
θ value	0.0961366 (rank : 283)	NC score	0.358786 (rank : 159)
Query Neighborhood Hits	458	Target Neighborhood Hits	553	Shared Neighborhood Hits	248
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.0961366 (rank : 284)	NC score	0.358059 (rank : 162)
Query Neighborhood Hits	458	Target Neighborhood Hits	502	Shared Neighborhood Hits	241
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MEGF8_HUMAN
θ value	0.0961366 (rank : 285)	NC score	0.397577 (rank : 101)
Query Neighborhood Hits	458	Target Neighborhood Hits	528	Shared Neighborhood Hits	244
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MUC2_HUMAN
θ value	0.0961366 (rank : 286)	NC score	0.129324 (rank : 541)
Query Neighborhood Hits	458	Target Neighborhood Hits	906	Shared Neighborhood Hits	153
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SSPO_MOUSE
θ value	0.0961366 (rank : 287)	NC score	0.220134 (rank : 331)
Query Neighborhood Hits	458	Target Neighborhood Hits	800	Shared Neighborhood Hits	245
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TIE2_MOUSE
θ value	0.0961366 (rank : 288)	NC score	0.251107 (rank : 278)
Query Neighborhood Hits	458	Target Neighborhood Hits	1204	Shared Neighborhood Hits	328
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

UROM_MOUSE
θ value	0.0961366 (rank : 289)	NC score	0.299021 (rank : 219)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	189
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ZAN_MOUSE
θ value	0.0961366 (rank : 290)	NC score	0.318293 (rank : 198)
Query Neighborhood Hits	458	Target Neighborhood Hits	808	Shared Neighborhood Hits	269
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CELR1_HUMAN
θ value	0.125558 (rank : 291)	NC score	0.215803 (rank : 339)
Query Neighborhood Hits	458	Target Neighborhood Hits	613	Shared Neighborhood Hits	220
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR2_MOUSE
θ value	0.125558 (rank : 292)	NC score	0.200359 (rank : 361)
Query Neighborhood Hits	458	Target Neighborhood Hits	584	Shared Neighborhood Hits	219
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

GRN_HUMAN
θ value	0.125558 (rank : 293)	NC score	0.232331 (rank : 304)
Query Neighborhood Hits	458	Target Neighborhood Hits	268	Shared Neighborhood Hits	135
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

IL6RB_HUMAN
θ value	0.125558 (rank : 294)	NC score	0.264867 (rank : 264)
Query Neighborhood Hits	458	Target Neighborhood Hits	181	Shared Neighborhood Hits	117
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

MEGF8_MOUSE
θ value	0.125558 (rank : 295)	NC score	0.388953 (rank : 118)
Query Neighborhood Hits	458	Target Neighborhood Hits	520	Shared Neighborhood Hits	242
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

AD26A_MOUSE
θ value	0.163984 (rank : 296)	NC score	0.072138 (rank : 847)
Query Neighborhood Hits	458	Target Neighborhood Hits	165	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

C1QR1_HUMAN
θ value	0.163984 (rank : 297)	NC score	0.308259 (rank : 207)
Query Neighborhood Hits	458	Target Neighborhood Hits	493	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CSF3R_HUMAN
θ value	0.163984 (rank : 298)	NC score	0.197172 (rank : 365)
Query Neighborhood Hits	458	Target Neighborhood Hits	140	Shared Neighborhood Hits	92
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

ELTD1_MOUSE
θ value	0.163984 (rank : 299)	NC score	0.208684 (rank : 351)
Query Neighborhood Hits	458	Target Neighborhood Hits	288	Shared Neighborhood Hits	148
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EPHA1_HUMAN
θ value	0.163984 (rank : 300)	NC score	0.122661 (rank : 567)
Query Neighborhood Hits	458	Target Neighborhood Hits	997	Shared Neighborhood Hits	165
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

MYBPH_HUMAN
θ value	0.163984 (rank : 301)	NC score	0.220311 (rank : 330)
Query Neighborhood Hits	458	Target Neighborhood Hits	256	Shared Neighborhood Hits	101
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NTNG2_MOUSE
θ value	0.163984 (rank : 302)	NC score	0.366930 (rank : 149)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	201
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ZN330_HUMAN
θ value	0.163984 (rank : 303)	NC score	0.073425 (rank : 838)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ADA11_HUMAN
θ value	0.21417 (rank : 304)	NC score	0.124198 (rank : 555)
Query Neighborhood Hits	458	Target Neighborhood Hits	259	Shared Neighborhood Hits	157
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	0.21417 (rank : 305)	NC score	0.123666 (rank : 558)
Query Neighborhood Hits	458	Target Neighborhood Hits	263	Shared Neighborhood Hits	158
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADAM9_MOUSE
θ value	0.21417 (rank : 306)	NC score	0.107041 (rank : 637)
Query Neighborhood Hits	458	Target Neighborhood Hits	325	Shared Neighborhood Hits	152
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ATBF1_HUMAN
θ value	0.21417 (rank : 307)	NC score	-0.006465 (rank : 1123)
Query Neighborhood Hits	458	Target Neighborhood Hits	1547	Shared Neighborhood Hits	17
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

COMP_HUMAN
θ value	0.21417 (rank : 308)	NC score	0.266198 (rank : 263)
Query Neighborhood Hits	458	Target Neighborhood Hits	258	Shared Neighborhood Hits	183
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

PROS_HUMAN
θ value	0.21417 (rank : 309)	NC score	0.316494 (rank : 202)
Query Neighborhood Hits	458	Target Neighborhood Hits	340	Shared Neighborhood Hits	210
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

ZN330_MOUSE
θ value	0.21417 (rank : 310)	NC score	0.071986 (rank : 848)
Query Neighborhood Hits	458	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	Q922H9, Q8C389, Q8K2M4	Gene names	Znf330, Noa36, Zfp330
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ADA24_MOUSE
θ value	0.279714 (rank : 311)	NC score	0.097606 (rank : 680)
Query Neighborhood Hits	458	Target Neighborhood Hits	230	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

KRA53_HUMAN
θ value	0.279714 (rank : 312)	NC score	0.518927 (rank : 31)
Query Neighborhood Hits	458	Target Neighborhood Hits	331	Shared Neighborhood Hits	187
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA59_HUMAN
θ value	0.279714 (rank : 313)	NC score	0.503544 (rank : 39)
Query Neighborhood Hits	458	Target Neighborhood Hits	310	Shared Neighborhood Hits	157
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MYLK_HUMAN
θ value	0.279714 (rank : 314)	NC score	0.133748 (rank : 530)
Query Neighborhood Hits	458	Target Neighborhood Hits	1328	Shared Neighborhood Hits	138
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NET1_HUMAN
θ value	0.279714 (rank : 315)	NC score	0.239293 (rank : 296)
Query Neighborhood Hits	458	Target Neighborhood Hits	149	Shared Neighborhood Hits	120
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	0.279714 (rank : 316)	NC score	0.234890 (rank : 299)
Query Neighborhood Hits	458	Target Neighborhood Hits	151	Shared Neighborhood Hits	119
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

PCSK5_MOUSE
θ value	0.279714 (rank : 317)	NC score	0.290198 (rank : 226)
Query Neighborhood Hits	458	Target Neighborhood Hits	613	Shared Neighborhood Hits	236
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

EGF_MOUSE
θ value	0.365318 (rank : 318)	NC score	0.287646 (rank : 230)
Query Neighborhood Hits	458	Target Neighborhood Hits	358	Shared Neighborhood Hits	210
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

MLL3_HUMAN
θ value	0.365318 (rank : 319)	NC score	0.025190 (rank : 1081)
Query Neighborhood Hits	458	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NET4_MOUSE
θ value	0.365318 (rank : 320)	NC score	0.267283 (rank : 260)
Query Neighborhood Hits	458	Target Neighborhood Hits	180	Shared Neighborhood Hits	149
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

PROC_MOUSE
θ value	0.365318 (rank : 321)	NC score	0.128808 (rank : 544)
Query Neighborhood Hits	458	Target Neighborhood Hits	426	Shared Neighborhood Hits	177
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TARA_HUMAN
θ value	0.365318 (rank : 322)	NC score	0.010404 (rank : 1102)
Query Neighborhood Hits	458	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRIM9_MOUSE
θ value	0.365318 (rank : 323)	NC score	0.051473 (rank : 1060)
Query Neighborhood Hits	458	Target Neighborhood Hits	274	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TYRO3_MOUSE
θ value	0.365318 (rank : 324)	NC score	0.150131 (rank : 496)
Query Neighborhood Hits	458	Target Neighborhood Hits	1007	Shared Neighborhood Hits	140
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

ADA17_MOUSE
θ value	0.47712 (rank : 325)	NC score	0.105954 (rank : 650)
Query Neighborhood Hits	458	Target Neighborhood Hits	201	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

EDIL3_HUMAN
θ value	0.47712 (rank : 326)	NC score	0.282719 (rank : 236)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	179
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_MOUSE
θ value	0.47712 (rank : 327)	NC score	0.325208 (rank : 188)
Query Neighborhood Hits	458	Target Neighborhood Hits	287	Shared Neighborhood Hits	183
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

KRA57_HUMAN
θ value	0.47712 (rank : 328)	NC score	0.473905 (rank : 52)
Query Neighborhood Hits	458	Target Neighborhood Hits	269	Shared Neighborhood Hits	161
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NTNG2_HUMAN
θ value	0.47712 (rank : 329)	NC score	0.358288 (rank : 161)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	197
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PTPRO_HUMAN
θ value	0.47712 (rank : 330)	NC score	0.145207 (rank : 508)
Query Neighborhood Hits	458	Target Neighborhood Hits	139	Shared Neighborhood Hits	58
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

TSP1_MOUSE
θ value	0.47712 (rank : 331)	NC score	0.208494 (rank : 352)
Query Neighborhood Hits	458	Target Neighborhood Hits	396	Shared Neighborhood Hits	184
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADA18_MOUSE
θ value	0.62314 (rank : 332)	NC score	0.109322 (rank : 624)
Query Neighborhood Hits	458	Target Neighborhood Hits	227	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA28_HUMAN
θ value	0.62314 (rank : 333)	NC score	0.110718 (rank : 616)
Query Neighborhood Hits	458	Target Neighborhood Hits	244	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA33_HUMAN
θ value	0.62314 (rank : 334)	NC score	0.094667 (rank : 701)
Query Neighborhood Hits	458	Target Neighborhood Hits	264	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM9_HUMAN
θ value	0.62314 (rank : 335)	NC score	0.096537 (rank : 687)
Query Neighborhood Hits	458	Target Neighborhood Hits	243	Shared Neighborhood Hits	132
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

FBLN4_HUMAN
θ value	0.62314 (rank : 336)	NC score	0.288202 (rank : 228)
Query Neighborhood Hits	458	Target Neighborhood Hits	278	Shared Neighborhood Hits	177
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

HABP2_HUMAN
θ value	0.62314 (rank : 337)	NC score	0.171000 (rank : 427)
Query Neighborhood Hits	458	Target Neighborhood Hits	431	Shared Neighborhood Hits	189
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	0.62314 (rank : 338)	NC score	0.169725 (rank : 431)
Query Neighborhood Hits	458	Target Neighborhood Hits	445	Shared Neighborhood Hits	192
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HTRA3_MOUSE
θ value	0.62314 (rank : 339)	NC score	0.033809 (rank : 1075)
Query Neighborhood Hits	458	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

NCAM2_HUMAN
θ value	0.62314 (rank : 340)	NC score	0.270750 (rank : 257)
Query Neighborhood Hits	458	Target Neighborhood Hits	441	Shared Neighborhood Hits	134
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

SLK_HUMAN
θ value	0.62314 (rank : 341)	NC score	0.023939 (rank : 1082)
Query Neighborhood Hits	458	Target Neighborhood Hits	1775	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ST14_MOUSE
θ value	0.62314 (rank : 342)	NC score	0.059358 (rank : 968)
Query Neighborhood Hits	458	Target Neighborhood Hits	419	Shared Neighborhood Hits	123
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ADAM8_MOUSE
θ value	0.813845 (rank : 343)	NC score	0.120484 (rank : 576)
Query Neighborhood Hits	458	Target Neighborhood Hits	326	Shared Neighborhood Hits	145
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CELR1_MOUSE
θ value	0.813845 (rank : 344)	NC score	0.211522 (rank : 348)
Query Neighborhood Hits	458	Target Neighborhood Hits	617	Shared Neighborhood Hits	232
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

EMR2_HUMAN
θ value	0.813845 (rank : 345)	NC score	0.238351 (rank : 297)
Query Neighborhood Hits	458	Target Neighborhood Hits	345	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

KRA54_HUMAN
θ value	0.813845 (rank : 346)	NC score	0.445226 (rank : 65)
Query Neighborhood Hits	458	Target Neighborhood Hits	270	Shared Neighborhood Hits	153
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

MGAT3_HUMAN
θ value	0.813845 (rank : 347)	NC score	0.041205 (rank : 1072)
Query Neighborhood Hits	458	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q09327, Q6IC49, Q9UH32	Gene names	MGAT3, GGNT3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

MGAT3_MOUSE
θ value	0.813845 (rank : 348)	NC score	0.038520 (rank : 1073)
Query Neighborhood Hits	458	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q10470, P70386	Gene names	Mgat3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

NCAM2_MOUSE
θ value	0.813845 (rank : 349)	NC score	0.277678 (rank : 248)
Query Neighborhood Hits	458	Target Neighborhood Hits	472	Shared Neighborhood Hits	136
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NET2_HUMAN
θ value	0.813845 (rank : 350)	NC score	0.267715 (rank : 258)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	150
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

TRI36_HUMAN
θ value	0.813845 (rank : 351)	NC score	0.020490 (rank : 1088)
Query Neighborhood Hits	458	Target Neighborhood Hits	282	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TSP1_HUMAN
θ value	0.813845 (rank : 352)	NC score	0.207630 (rank : 354)
Query Neighborhood Hits	458	Target Neighborhood Hits	389	Shared Neighborhood Hits	182
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

VWF_HUMAN
θ value	0.813845 (rank : 353)	NC score	0.178284 (rank : 411)
Query Neighborhood Hits	458	Target Neighborhood Hits	396	Shared Neighborhood Hits	167
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

NELL1_HUMAN
θ value	1.06291 (rank : 354)	NC score	0.384697 (rank : 125)
Query Neighborhood Hits	458	Target Neighborhood Hits	451	Shared Neighborhood Hits	241
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SIX4_HUMAN
θ value	1.06291 (rank : 355)	NC score	0.003994 (rank : 1112)
Query Neighborhood Hits	458	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIU6	Gene names	SIX4
Domain Architecture
Description	Homeobox protein SIX4 (Sine oculis homeobox homolog 4).

CD97_HUMAN
θ value	1.38821 (rank : 356)	NC score	0.233459 (rank : 302)
Query Neighborhood Hits	458	Target Neighborhood Hits	353	Shared Neighborhood Hits	177
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR1_MOUSE
θ value	1.38821 (rank : 357)	NC score	0.234757 (rank : 300)
Query Neighborhood Hits	458	Target Neighborhood Hits	349	Shared Neighborhood Hits	162
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

HMCN1_HUMAN
θ value	1.38821 (rank : 358)	NC score	0.347921 (rank : 166)
Query Neighborhood Hits	458	Target Neighborhood Hits	983	Shared Neighborhood Hits	283
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LIFR_MOUSE
θ value	1.38821 (rank : 359)	NC score	0.214679 (rank : 341)
Query Neighborhood Hits	458	Target Neighborhood Hits	127	Shared Neighborhood Hits	87
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

NET2_MOUSE
θ value	1.38821 (rank : 360)	NC score	0.273991 (rank : 251)
Query Neighborhood Hits	458	Target Neighborhood Hits	193	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NID2_HUMAN
θ value	1.38821 (rank : 361)	NC score	0.293234 (rank : 224)
Query Neighborhood Hits	458	Target Neighborhood Hits	456	Shared Neighborhood Hits	204
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

PCD16_HUMAN
θ value	1.38821 (rank : 362)	NC score	0.012796 (rank : 1097)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

SLK_MOUSE
θ value	1.38821 (rank : 363)	NC score	0.023173 (rank : 1083)
Query Neighborhood Hits	458	Target Neighborhood Hits	1798	Shared Neighborhood Hits	62
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TRIM9_HUMAN
θ value	1.38821 (rank : 364)	NC score	0.055471 (rank : 1007)
Query Neighborhood Hits	458	Target Neighborhood Hits	294	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

UROM_HUMAN
θ value	1.38821 (rank : 365)	NC score	0.300971 (rank : 218)
Query Neighborhood Hits	458	Target Neighborhood Hits	284	Shared Neighborhood Hits	188
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ADA12_HUMAN
θ value	1.81305 (rank : 366)	NC score	0.077805 (rank : 807)
Query Neighborhood Hits	458	Target Neighborhood Hits	224	Shared Neighborhood Hits	109
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM2_MOUSE
θ value	1.81305 (rank : 367)	NC score	0.095816 (rank : 691)
Query Neighborhood Hits	458	Target Neighborhood Hits	209	Shared Neighborhood Hits	119
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

BORG1_HUMAN
θ value	1.81305 (rank : 368)	NC score	0.011042 (rank : 1100)
Query Neighborhood Hits	458	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

CO8A_MOUSE
θ value	1.81305 (rank : 369)	NC score	0.052379 (rank : 1056)
Query Neighborhood Hits	458	Target Neighborhood Hits	182	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

EPHAA_HUMAN
θ value	1.81305 (rank : 370)	NC score	0.142131 (rank : 511)
Query Neighborhood Hits	458	Target Neighborhood Hits	960	Shared Neighborhood Hits	150
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

LAMA4_HUMAN
θ value	1.81305 (rank : 371)	NC score	0.272573 (rank : 253)
Query Neighborhood Hits	458	Target Neighborhood Hits	708	Shared Neighborhood Hits	194
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

NID2_MOUSE
θ value	1.81305 (rank : 372)	NC score	0.277878 (rank : 247)
Query Neighborhood Hits	458	Target Neighborhood Hits	338	Shared Neighborhood Hits	189
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

TARSH_HUMAN
θ value	1.81305 (rank : 373)	NC score	0.162879 (rank : 454)
Query Neighborhood Hits	458	Target Neighborhood Hits	768	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

KRA52_HUMAN
θ value	2.36792 (rank : 374)	NC score	0.407172 (rank : 93)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	137
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA56_HUMAN
θ value	2.36792 (rank : 375)	NC score	0.455449 (rank : 61)
Query Neighborhood Hits	458	Target Neighborhood Hits	207	Shared Neighborhood Hits	136
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LRP2_HUMAN
θ value	2.36792 (rank : 376)	NC score	0.259567 (rank : 267)
Query Neighborhood Hits	458	Target Neighborhood Hits	573	Shared Neighborhood Hits	257
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

MLL3_MOUSE
θ value	2.36792 (rank : 377)	NC score	0.031134 (rank : 1076)
Query Neighborhood Hits	458	Target Neighborhood Hits	1399	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PROC_HUMAN
θ value	2.36792 (rank : 378)	NC score	0.111978 (rank : 609)
Query Neighborhood Hits	458	Target Neighborhood Hits	406	Shared Neighborhood Hits	171
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

ST14_HUMAN
θ value	2.36792 (rank : 379)	NC score	0.058519 (rank : 977)
Query Neighborhood Hits	458	Target Neighborhood Hits	409	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

UB7I1_HUMAN
θ value	2.36792 (rank : 380)	NC score	0.016401 (rank : 1092)
Query Neighborhood Hits	458	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

UB7I1_MOUSE
θ value	2.36792 (rank : 381)	NC score	0.017705 (rank : 1091)
Query Neighborhood Hits	458	Target Neighborhood Hits	206	Shared Neighborhood Hits	12
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

CD68_HUMAN
θ value	3.0926 (rank : 382)	NC score	0.011611 (rank : 1099)
Query Neighborhood Hits	458	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	P34810, Q96BI7	Gene names	CD68
Domain Architecture
Description	Macrosialin precursor (GP110) (CD68 antigen).

CO7_HUMAN
θ value	3.0926 (rank : 383)	NC score	0.092460 (rank : 715)
Query Neighborhood Hits	458	Target Neighborhood Hits	278	Shared Neighborhood Hits	108
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CSPG2_MOUSE
θ value	3.0926 (rank : 384)	NC score	0.242518 (rank : 292)
Query Neighborhood Hits	458	Target Neighborhood Hits	711	Shared Neighborhood Hits	212
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DIAP3_HUMAN
θ value	3.0926 (rank : 385)	NC score	0.002807 (rank : 1116)
Query Neighborhood Hits	458	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

EGF_HUMAN
θ value	3.0926 (rank : 386)	NC score	0.256175 (rank : 270)
Query Neighborhood Hits	458	Target Neighborhood Hits	343	Shared Neighborhood Hits	199
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

FA10_HUMAN
θ value	3.0926 (rank : 387)	NC score	0.126116 (rank : 552)
Query Neighborhood Hits	458	Target Neighborhood Hits	431	Shared Neighborhood Hits	172
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
θ value	3.0926 (rank : 388)	NC score	0.114124 (rank : 595)
Query Neighborhood Hits	458	Target Neighborhood Hits	425	Shared Neighborhood Hits	168
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

GRN_MOUSE
θ value	3.0926 (rank : 389)	NC score	0.228080 (rank : 316)
Query Neighborhood Hits	458	Target Neighborhood Hits	248	Shared Neighborhood Hits	134
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

IL27B_HUMAN
θ value	3.0926 (rank : 390)	NC score	0.113042 (rank : 601)
Query Neighborhood Hits	458	Target Neighborhood Hits	80	Shared Neighborhood Hits	56
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

IL4RA_HUMAN
θ value	3.0926 (rank : 391)	NC score	0.026245 (rank : 1080)
Query Neighborhood Hits	458	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

JAM2_HUMAN
θ value	3.0926 (rank : 392)	NC score	0.151307 (rank : 494)
Query Neighborhood Hits	458	Target Neighborhood Hits	304	Shared Neighborhood Hits	74
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

LAMA4_MOUSE
θ value	3.0926 (rank : 393)	NC score	0.290636 (rank : 225)
Query Neighborhood Hits	458	Target Neighborhood Hits	584	Shared Neighborhood Hits	192
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MYPC1_HUMAN
θ value	3.0926 (rank : 394)	NC score	0.255787 (rank : 271)
Query Neighborhood Hits	458	Target Neighborhood Hits	303	Shared Neighborhood Hits	108
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

NPHN_MOUSE
θ value	3.0926 (rank : 395)	NC score	0.244539 (rank : 288)
Query Neighborhood Hits	458	Target Neighborhood Hits	370	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

PMYT1_MOUSE
θ value	3.0926 (rank : 396)	NC score	0.022513 (rank : 1085)
Query Neighborhood Hits	458	Target Neighborhood Hits	910	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

WDR1_MOUSE
θ value	3.0926 (rank : 397)	NC score	-0.001960 (rank : 1121)
Query Neighborhood Hits	458	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

ADA12_MOUSE
θ value	4.03905 (rank : 398)	NC score	0.072895 (rank : 843)
Query Neighborhood Hits	458	Target Neighborhood Hits	474	Shared Neighborhood Hits	111
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_MOUSE
θ value	4.03905 (rank : 399)	NC score	0.123618 (rank : 560)
Query Neighborhood Hits	458	Target Neighborhood Hits	324	Shared Neighborhood Hits	169
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ATS8_MOUSE
θ value	4.03905 (rank : 400)	NC score	0.013979 (rank : 1095)
Query Neighborhood Hits	458	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

FATH_HUMAN
θ value	4.03905 (rank : 401)	NC score	0.219199 (rank : 333)
Query Neighborhood Hits	458	Target Neighborhood Hits	570	Shared Neighborhood Hits	225
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

MATN2_HUMAN
θ value	4.03905 (rank : 402)	NC score	0.289123 (rank : 227)
Query Neighborhood Hits	458	Target Neighborhood Hits	365	Shared Neighborhood Hits	191
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MUC5B_HUMAN
θ value	4.03905 (rank : 403)	NC score	0.174206 (rank : 422)
Query Neighborhood Hits	458	Target Neighborhood Hits	1020	Shared Neighborhood Hits	222
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PAR10_HUMAN
θ value	4.03905 (rank : 404)	NC score	0.010947 (rank : 1101)
Query Neighborhood Hits	458	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

TYRO3_HUMAN
θ value	4.03905 (rank : 405)	NC score	0.152551 (rank : 490)
Query Neighborhood Hits	458	Target Neighborhood Hits	995	Shared Neighborhood Hits	135
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

VLDLR_HUMAN
θ value	4.03905 (rank : 406)	NC score	0.239366 (rank : 295)
Query Neighborhood Hits	458	Target Neighborhood Hits	383	Shared Neighborhood Hits	198
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WN10B_HUMAN
θ value	4.03905 (rank : 407)	NC score	0.002875 (rank : 1114)
Query Neighborhood Hits	458	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	O00744, O00747, Q8WZ97	Gene names	WNT10B, WNT12
Domain Architecture
Description	Protein Wnt-10b precursor (Wnt-12).

WN10B_MOUSE
θ value	4.03905 (rank : 408)	NC score	0.002865 (rank : 1115)
Query Neighborhood Hits	458	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	P48614, P70702	Gene names	Wnt10b, Wnt-10b, Wnt10, Wnt12
Domain Architecture
Description	Protein Wnt-10b precursor (Wnt-12).

ABP1_HUMAN
θ value	5.27518 (rank : 409)	NC score	0.004712 (rank : 1111)
Query Neighborhood Hits	458	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P19801, Q16683, Q16684, Q56II4, Q6GU42	Gene names	ABP1, AOC1, DAO1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase) (Kidney amine oxidase) (KAO).

CO4A2_HUMAN
θ value	5.27518 (rank : 410)	NC score	0.017765 (rank : 1090)
Query Neighborhood Hits	458	Target Neighborhood Hits	454	Shared Neighborhood Hits	17
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

EGFL7_HUMAN
θ value	5.27518 (rank : 411)	NC score	0.337556 (rank : 170)
Query Neighborhood Hits	458	Target Neighborhood Hits	325	Shared Neighborhood Hits	198
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL8_HUMAN
θ value	5.27518 (rank : 412)	NC score	0.283100 (rank : 234)
Query Neighborhood Hits	458	Target Neighborhood Hits	270	Shared Neighborhood Hits	170
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

FAT2_HUMAN
θ value	5.27518 (rank : 413)	NC score	0.128058 (rank : 546)
Query Neighborhood Hits	458	Target Neighborhood Hits	507	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FBLN3_HUMAN
θ value	5.27518 (rank : 414)	NC score	0.275375 (rank : 250)
Query Neighborhood Hits	458	Target Neighborhood Hits	293	Shared Neighborhood Hits	184
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

HTRA3_HUMAN
θ value	5.27518 (rank : 415)	NC score	0.033820 (rank : 1074)
Query Neighborhood Hits	458	Target Neighborhood Hits	152	Shared Neighborhood Hits	24
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

MEF2A_HUMAN
θ value	5.27518 (rank : 416)	NC score	0.004723 (rank : 1110)
Query Neighborhood Hits	458	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

MYLK_MOUSE
θ value	5.27518 (rank : 417)	NC score	0.131757 (rank : 534)
Query Neighborhood Hits	458	Target Neighborhood Hits	1489	Shared Neighborhood Hits	143
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NET4_HUMAN
θ value	5.27518 (rank : 418)	NC score	0.267513 (rank : 259)
Query Neighborhood Hits	458	Target Neighborhood Hits	191	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NID1_HUMAN
θ value	5.27518 (rank : 419)	NC score	0.271611 (rank : 256)
Query Neighborhood Hits	458	Target Neighborhood Hits	329	Shared Neighborhood Hits	193
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NRX2A_HUMAN
θ value	5.27518 (rank : 420)	NC score	0.121129 (rank : 574)
Query Neighborhood Hits	458	Target Neighborhood Hits	614	Shared Neighborhood Hits	119
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

RN167_HUMAN
θ value	5.27518 (rank : 421)	NC score	0.001999 (rank : 1119)
Query Neighborhood Hits	458	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

ALMS1_MOUSE
θ value	6.88961 (rank : 422)	NC score	0.006923 (rank : 1104)
Query Neighborhood Hits	458	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

CO8A_HUMAN
θ value	6.88961 (rank : 423)	NC score	0.057934 (rank : 980)
Query Neighborhood Hits	458	Target Neighborhood Hits	200	Shared Neighborhood Hits	77
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CSF3R_MOUSE
θ value	6.88961 (rank : 424)	NC score	0.147459 (rank : 503)
Query Neighborhood Hits	458	Target Neighborhood Hits	104	Shared Neighborhood Hits	72
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CSPG2_HUMAN
θ value	6.88961 (rank : 425)	NC score	0.238294 (rank : 298)
Query Neighborhood Hits	458	Target Neighborhood Hits	681	Shared Neighborhood Hits	212
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

EGFR_HUMAN
θ value	6.88961 (rank : 426)	NC score	0.071246 (rank : 854)
Query Neighborhood Hits	458	Target Neighborhood Hits	939	Shared Neighborhood Hits	103
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

FAM5A_HUMAN
θ value	6.88961 (rank : 427)	NC score	0.006338 (rank : 1108)
Query Neighborhood Hits	458	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O60477, Q6IPV6, Q6P1A0, Q8WU22	Gene names	FAM5A, DBC1, DBCCR1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein).

FAM5A_MOUSE
θ value	6.88961 (rank : 428)	NC score	0.006093 (rank : 1109)
Query Neighborhood Hits	458	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q920P3, Q80ZL2, Q812F0, Q8C1C9, Q920P4, Q9QXL0	Gene names	Fam5a, Brinp, Brinp1, Dbccr1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein homolog) (BMP/retinoic acid-inducible neural-specific protein 1).

FIBP_HUMAN
θ value	6.88961 (rank : 429)	NC score	0.008367 (rank : 1103)
Query Neighborhood Hits	458	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O43427, Q6IBQ3, Q9HD65	Gene names	FIBP
Domain Architecture
Description	Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein).

I12R2_HUMAN
θ value	6.88961 (rank : 430)	NC score	0.225901 (rank : 321)
Query Neighborhood Hits	458	Target Neighborhood Hits	163	Shared Neighborhood Hits	108
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

LRC21_MOUSE
θ value	6.88961 (rank : 431)	NC score	0.119997 (rank : 577)
Query Neighborhood Hits	458	Target Neighborhood Hits	462	Shared Neighborhood Hits	98
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

MYH1_HUMAN
θ value	6.88961 (rank : 432)	NC score	0.002583 (rank : 1117)
Query Neighborhood Hits	458	Target Neighborhood Hits	1478	Shared Neighborhood Hits	32
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

NPHN_HUMAN
θ value	6.88961 (rank : 433)	NC score	0.253101 (rank : 274)
Query Neighborhood Hits	458	Target Neighborhood Hits	362	Shared Neighborhood Hits	106
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

TYRP1_HUMAN
θ value	6.88961 (rank : 434)	NC score	0.030433 (rank : 1077)
Query Neighborhood Hits	458	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

UHMK1_MOUSE
θ value	6.88961 (rank : 435)	NC score	0.026915 (rank : 1079)
Query Neighborhood Hits	458	Target Neighborhood Hits	809	Shared Neighborhood Hits	46
SwissProt Accessions	P97343, Q61775, Q9CYT1	Gene names	Uhmk1, Kis, Kist
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

5NT1B_MOUSE
θ value	8.99809 (rank : 436)	NC score	0.006808 (rank : 1105)
Query Neighborhood Hits	458	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

APBP2_HUMAN
θ value	8.99809 (rank : 437)	NC score	0.006384 (rank : 1106)
Query Neighborhood Hits	458	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q92624, O95095, Q8WVC9	Gene names	APPBP2, KIAA0228, PAT1
Domain Architecture	No domain graphic available
Description	Amyloid protein-binding protein 2 (Amyloid beta precursor protein- binding protein 2) (APP-BP2) (Protein interacting with APP tail 1).

APBP2_MOUSE
θ value	8.99809 (rank : 438)	NC score	0.006381 (rank : 1107)
Query Neighborhood Hits	458	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DAX9, Q80U61	Gene names	Appbp2, Kiaa0228
Domain Architecture	No domain graphic available
Description	Amyloid protein-binding protein 2 (Amyloid beta precursor protein- binding protein 2) (APP-BP2).

CHK1_HUMAN
θ value	8.99809 (rank : 439)	NC score	0.019204 (rank : 1089)
Query Neighborhood Hits	458	Target Neighborhood Hits	843	Shared Neighborhood Hits	50
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

DKK2_HUMAN
θ value	8.99809 (rank : 440)	NC score	0.021965 (rank : 1086)
Query Neighborhood Hits	458	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBU2, Q9UIU3	Gene names	DKK2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (hDkk-2).

DKK2_MOUSE
θ value	8.99809 (rank : 441)	NC score	0.022739 (rank : 1084)
Query Neighborhood Hits	458	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QYZ8	Gene names	Dkk2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (mDkk-2).

I27RA_HUMAN
θ value	8.99809 (rank : 442)	NC score	0.089573 (rank : 733)
Query Neighborhood Hits	458	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

IL6RB_MOUSE
θ value	8.99809 (rank : 443)	NC score	0.230605 (rank : 307)
Query Neighborhood Hits	458	Target Neighborhood Hits	168	Shared Neighborhood Hits	117
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

LRP4_MOUSE
θ value	8.99809 (rank : 444)	NC score	0.205459 (rank : 356)
Query Neighborhood Hits	458	Target Neighborhood Hits	351	Shared Neighborhood Hits	188
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LYAM1_MOUSE
θ value	8.99809 (rank : 445)	NC score	0.149128 (rank : 499)
Query Neighborhood Hits	458	Target Neighborhood Hits	332	Shared Neighborhood Hits	156
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MAP4_HUMAN
θ value	8.99809 (rank : 446)	NC score	0.011764 (rank : 1098)
Query Neighborhood Hits	458	Target Neighborhood Hits	428	Shared Neighborhood Hits	18
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MFGM_MOUSE
θ value	8.99809 (rank : 447)	NC score	0.224621 (rank : 323)
Query Neighborhood Hits	458	Target Neighborhood Hits	233	Shared Neighborhood Hits	154
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MYH1_MOUSE
θ value	8.99809 (rank : 448)	NC score	0.002051 (rank : 1118)
Query Neighborhood Hits	458	Target Neighborhood Hits	1461	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	8.99809 (rank : 449)	NC score	0.001789 (rank : 1120)
Query Neighborhood Hits	458	Target Neighborhood Hits	1491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYPC2_HUMAN
θ value	8.99809 (rank : 450)	NC score	0.266878 (rank : 262)
Query Neighborhood Hits	458	Target Neighborhood Hits	316	Shared Neighborhood Hits	120
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NRX1A_HUMAN
θ value	8.99809 (rank : 451)	NC score	0.131881 (rank : 533)
Query Neighborhood Hits	458	Target Neighborhood Hits	170	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX3A_HUMAN
θ value	8.99809 (rank : 452)	NC score	0.121921 (rank : 571)
Query Neighborhood Hits	458	Target Neighborhood Hits	164	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PODXL_HUMAN
θ value	8.99809 (rank : 453)	NC score	0.012899 (rank : 1096)
Query Neighborhood Hits	458	Target Neighborhood Hits	191	Shared Neighborhood Hits	15
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

TCF17_HUMAN
θ value	8.99809 (rank : 454)	NC score	-0.011828 (rank : 1124)
Query Neighborhood Hits	458	Target Neighborhood Hits	797	Shared Neighborhood Hits	18
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

TMPS2_HUMAN
θ value	8.99809 (rank : 455)	NC score	0.002992 (rank : 1113)
Query Neighborhood Hits	458	Target Neighborhood Hits	252	Shared Neighborhood Hits	23
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TRI36_MOUSE
θ value	8.99809 (rank : 456)	NC score	0.020635 (rank : 1087)
Query Neighborhood Hits	458	Target Neighborhood Hits	266	Shared Neighborhood Hits	33
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TSP4_HUMAN
θ value	8.99809 (rank : 457)	NC score	0.287496 (rank : 231)
Query Neighborhood Hits	458	Target Neighborhood Hits	277	Shared Neighborhood Hits	186
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

WDR67_HUMAN
θ value	8.99809 (rank : 458)	NC score	-0.005485 (rank : 1122)
Query Neighborhood Hits	458	Target Neighborhood Hits	782	Shared Neighborhood Hits	10
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

AATK_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.056209 (rank : 996)
Query Neighborhood Hits	458	Target Neighborhood Hits	1243	Shared Neighborhood Hits	61
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AATK_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.057900 (rank : 981)
Query Neighborhood Hits	458	Target Neighborhood Hits	942	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABL1_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.053669 (rank : 1040)
Query Neighborhood Hits	458	Target Neighborhood Hits	1220	Shared Neighborhood Hits	52
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.054183 (rank : 1034)
Query Neighborhood Hits	458	Target Neighborhood Hits	1178	Shared Neighborhood Hits	56
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.053494 (rank : 1044)
Query Neighborhood Hits	458	Target Neighborhood Hits	1045	Shared Neighborhood Hits	49
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ACK1_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.059573 (rank : 964)
Query Neighborhood Hits	458	Target Neighborhood Hits	1140	Shared Neighborhood Hits	60
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.060512 (rank : 952)
Query Neighborhood Hits	458	Target Neighborhood Hits	1080	Shared Neighborhood Hits	61
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ADA10_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.094267 (rank : 703)
Query Neighborhood Hits	458	Target Neighborhood Hits	189	Shared Neighborhood Hits	90
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.093843 (rank : 706)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	88
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA15_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.116374 (rank : 587)
Query Neighborhood Hits	458	Target Neighborhood Hits	288	Shared Neighborhood Hits	149
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA18_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.094175 (rank : 704)
Query Neighborhood Hits	458	Target Neighborhood Hits	184	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA21_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.066955 (rank : 886)
Query Neighborhood Hits	458	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.073159 (rank : 839)
Query Neighborhood Hits	458	Target Neighborhood Hits	172	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.097098 (rank : 683)
Query Neighborhood Hits	458	Target Neighborhood Hits	211	Shared Neighborhood Hits	119
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.102294 (rank : 665)
Query Neighborhood Hits	458	Target Neighborhood Hits	225	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.109837 (rank : 620)
Query Neighborhood Hits	458	Target Neighborhood Hits	235	Shared Neighborhood Hits	141
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.105840 (rank : 652)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	148
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA25_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.074828 (rank : 829)
Query Neighborhood Hits	458	Target Neighborhood Hits	213	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA29_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.063342 (rank : 924)
Query Neighborhood Hits	458	Target Neighborhood Hits	247	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA30_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.080860 (rank : 792)
Query Neighborhood Hits	458	Target Neighborhood Hits	391	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA32_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.086385 (rank : 747)
Query Neighborhood Hits	458	Target Neighborhood Hits	216	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.086390 (rank : 746)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	116
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA33_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.100909 (rank : 666)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	134
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.077938 (rank : 806)
Query Neighborhood Hits	458	Target Neighborhood Hits	175	Shared Neighborhood Hits	94
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM7_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.078538 (rank : 803)
Query Neighborhood Hits	458	Target Neighborhood Hits	221	Shared Neighborhood Hits	127
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.068268 (rank : 878)
Query Neighborhood Hits	458	Target Neighborhood Hits	200	Shared Neighborhood Hits	105
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM8_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.121995 (rank : 570)
Query Neighborhood Hits	458	Target Neighborhood Hits	327	Shared Neighborhood Hits	153
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADM1A_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.073058 (rank : 841)
Query Neighborhood Hits	458	Target Neighborhood Hits	230	Shared Neighborhood Hits	122
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.071389 (rank : 853)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	109
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ALK_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.069668 (rank : 867)
Query Neighborhood Hits	458	Target Neighborhood Hits	795	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.070119 (rank : 865)
Query Neighborhood Hits	458	Target Neighborhood Hits	811	Shared Neighborhood Hits	69
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ANGL1_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.063394 (rank : 921)
Query Neighborhood Hits	458	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	O95841, Q5T5Z5	Gene names	ANGPTL1, ANG3, ANGPT3, ARP1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1) (Angiopoietin-3) (ANG-3).

ANGL1_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.063842 (rank : 917)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

ANGL2_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.064330 (rank : 913)
Query Neighborhood Hits	458	Target Neighborhood Hits	104	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL2_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.064383 (rank : 912)
Query Neighborhood Hits	458	Target Neighborhood Hits	108	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL3_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.055968 (rank : 999)
Query Neighborhood Hits	458	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

ANGL3_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.060223 (rank : 959)
Query Neighborhood Hits	458	Target Neighborhood Hits	306	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ANGL4_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.061691 (rank : 940)
Query Neighborhood Hits	458	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

ANGL4_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.062285 (rank : 932)
Query Neighborhood Hits	458	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

ANGL5_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.068022 (rank : 880)
Query Neighborhood Hits	458	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

ANGL6_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.067615 (rank : 884)
Query Neighborhood Hits	458	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

ANGL6_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.068988 (rank : 873)
Query Neighborhood Hits	458	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

ANGL7_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.068801 (rank : 875)
Query Neighborhood Hits	458	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

ANGL7_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.069096 (rank : 871)
Query Neighborhood Hits	458	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

ANGP1_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.061076 (rank : 945)
Query Neighborhood Hits	458	Target Neighborhood Hits	254	Shared Neighborhood Hits	14
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP1_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.060220 (rank : 960)
Query Neighborhood Hits	458	Target Neighborhood Hits	252	Shared Neighborhood Hits	13
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP2_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.056383 (rank : 994)
Query Neighborhood Hits	458	Target Neighborhood Hits	400	Shared Neighborhood Hits	12
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGP2_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.055794 (rank : 1002)
Query Neighborhood Hits	458	Target Neighborhood Hits	397	Shared Neighborhood Hits	13
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGP4_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.063374 (rank : 922)
Query Neighborhood Hits	458	Target Neighborhood Hits	187	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ANGP4_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.060910 (rank : 946)
Query Neighborhood Hits	458	Target Neighborhood Hits	220	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

APR3_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.085498 (rank : 752)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.097230 (rank : 682)
Query Neighborhood Hits	458	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASTN_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.053641 (rank : 1042)
Query Neighborhood Hits	458	Target Neighborhood Hits	105	Shared Neighborhood Hits	49
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.055560 (rank : 1005)
Query Neighborhood Hits	458	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATL3_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.131665 (rank : 535)
Query Neighborhood Hits	458	Target Neighborhood Hits	414	Shared Neighborhood Hits	104
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

BASI_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.168339 (rank : 438)
Query Neighborhood Hits	458	Target Neighborhood Hits	211	Shared Neighborhood Hits	66
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

BASI_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.160860 (rank : 460)
Query Neighborhood Hits	458	Target Neighborhood Hits	238	Shared Neighborhood Hits	67
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

BLK_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.054451 (rank : 1026)
Query Neighborhood Hits	458	Target Neighborhood Hits	994	Shared Neighborhood Hits	50
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.055018 (rank : 1016)
Query Neighborhood Hits	458	Target Neighborhood Hits	992	Shared Neighborhood Hits	50
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BMP1_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.070315 (rank : 863)
Query Neighborhood Hits	458	Target Neighborhood Hits	233	Shared Neighborhood Hits	102
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.071129 (rank : 855)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	103
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMPER_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.089878 (rank : 732)
Query Neighborhood Hits	458	Target Neighborhood Hits	175	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.097047 (rank : 684)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BMX_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.054611 (rank : 1022)
Query Neighborhood Hits	458	Target Neighborhood Hits	942	Shared Neighborhood Hits	52
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.055066 (rank : 1015)
Query Neighborhood Hits	458	Target Neighborhood Hits	912	Shared Neighborhood Hits	51
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BTK_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.054188 (rank : 1033)
Query Neighborhood Hits	458	Target Neighborhood Hits	1026	Shared Neighborhood Hits	51
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.054248 (rank : 1032)
Query Neighborhood Hits	458	Target Neighborhood Hits	1017	Shared Neighborhood Hits	51
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

C1QR1_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.282766 (rank : 235)
Query Neighborhood Hits	458	Target Neighborhood Hits	342	Shared Neighborhood Hits	193
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD166_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.104513 (rank : 658)
Query Neighborhood Hits	458	Target Neighborhood Hits	247	Shared Neighborhood Hits	58
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

CD166_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.116986 (rank : 583)
Query Neighborhood Hits	458	Target Neighborhood Hits	252	Shared Neighborhood Hits	62
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

CD22_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.156943 (rank : 477)
Query Neighborhood Hits	458	Target Neighborhood Hits	365	Shared Neighborhood Hits	70
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD22_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.166876 (rank : 442)
Query Neighborhood Hits	458	Target Neighborhood Hits	331	Shared Neighborhood Hits	67
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD248_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.199584 (rank : 363)
Query Neighborhood Hits	458	Target Neighborhood Hits	679	Shared Neighborhood Hits	178
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.194249 (rank : 373)
Query Neighborhood Hits	458	Target Neighborhood Hits	578	Shared Neighborhood Hits	166
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD276_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.093602 (rank : 708)
Query Neighborhood Hits	458	Target Neighborhood Hits	261	Shared Neighborhood Hits	49
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.058669 (rank : 973)
Query Neighborhood Hits	458	Target Neighborhood Hits	243	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD320_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.052674 (rank : 1052)
Query Neighborhood Hits	458	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD45_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.128862 (rank : 543)
Query Neighborhood Hits	458	Target Neighborhood Hits	243	Shared Neighborhood Hits	65
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD79A_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.063106 (rank : 926)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CD97_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.187127 (rank : 385)
Query Neighborhood Hits	458	Target Neighborhood Hits	295	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CEA20_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.146326 (rank : 505)
Query Neighborhood Hits	458	Target Neighborhood Hits	251	Shared Neighborhood Hits	67
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

CEAM1_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.130657 (rank : 537)
Query Neighborhood Hits	458	Target Neighborhood Hits	348	Shared Neighborhood Hits	70
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

CEAM1_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.145766 (rank : 506)
Query Neighborhood Hits	458	Target Neighborhood Hits	326	Shared Neighborhood Hits	68
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CEAM5_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.156626 (rank : 478)
Query Neighborhood Hits	458	Target Neighborhood Hits	343	Shared Neighborhood Hits	73
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

CEAM6_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.109663 (rank : 621)
Query Neighborhood Hits	458	Target Neighborhood Hits	308	Shared Neighborhood Hits	71
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

CEAM7_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.057734 (rank : 984)
Query Neighborhood Hits	458	Target Neighborhood Hits	170	Shared Neighborhood Hits	52
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

CEAM8_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.094577 (rank : 702)
Query Neighborhood Hits	458	Target Neighborhood Hits	264	Shared Neighborhood Hits	67
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

CFC1_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.210906 (rank : 349)
Query Neighborhood Hits	458	Target Neighborhood Hits	148	Shared Neighborhood Hits	123
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.179515 (rank : 407)
Query Neighborhood Hits	458	Target Neighborhood Hits	125	Shared Neighborhood Hits	105
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CI094_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.177491 (rank : 415)
Query Neighborhood Hits	458	Target Neighborhood Hits	310	Shared Neighborhood Hits	81
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.093333 (rank : 712)
Query Neighborhood Hits	458	Target Neighborhood Hits	266	Shared Neighborhood Hits	82
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.091057 (rank : 725)
Query Neighborhood Hits	458	Target Neighborhood Hits	282	Shared Neighborhood Hits	78
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP2_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.121080 (rank : 575)
Query Neighborhood Hits	458	Target Neighborhood Hits	307	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CLC14_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.067704 (rank : 882)
Query Neighborhood Hits	458	Target Neighborhood Hits	143	Shared Neighborhood Hits	72
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.065293 (rank : 902)
Query Neighborhood Hits	458	Target Neighborhood Hits	120	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CNTP1_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.088076 (rank : 737)
Query Neighborhood Hits	458	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.084906 (rank : 761)
Query Neighborhood Hits	458	Target Neighborhood Hits	183	Shared Neighborhood Hits	92
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.105120 (rank : 655)
Query Neighborhood Hits	458	Target Neighborhood Hits	199	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.105845 (rank : 651)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	109
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.093640 (rank : 707)
Query Neighborhood Hits	458	Target Neighborhood Hits	195	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.100885 (rank : 667)
Query Neighborhood Hits	458	Target Neighborhood Hits	187	Shared Neighborhood Hits	99
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.102551 (rank : 664)
Query Neighborhood Hits	458	Target Neighborhood Hits	193	Shared Neighborhood Hits	106
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO6_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.095225 (rank : 697)
Query Neighborhood Hits	458	Target Neighborhood Hits	331	Shared Neighborhood Hits	118
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO8B_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.055992 (rank : 997)
Query Neighborhood Hits	458	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.082072 (rank : 784)
Query Neighborhood Hits	458	Target Neighborhood Hits	224	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.054503 (rank : 1025)
Query Neighborhood Hits	458	Target Neighborhood Hits	153	Shared Neighborhood Hits	65
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CORIN_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.084922 (rank : 760)
Query Neighborhood Hits	458	Target Neighborhood Hits	453	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.080621 (rank : 794)
Query Neighborhood Hits	458	Target Neighborhood Hits	451	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CRAC1_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.080406 (rank : 796)
Query Neighborhood Hits	458	Target Neighborhood Hits	111	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.081388 (rank : 787)
Query Neighborhood Hits	458	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRLF1_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.108224 (rank : 633)
Query Neighborhood Hits	458	Target Neighborhood Hits	122	Shared Neighborhood Hits	75
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.106646 (rank : 644)
Query Neighborhood Hits	458	Target Neighborhood Hits	116	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CSF1R_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.086304 (rank : 748)
Query Neighborhood Hits	458	Target Neighborhood Hits	943	Shared Neighborhood Hits	101
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF1R_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.107696 (rank : 636)
Query Neighborhood Hits	458	Target Neighborhood Hits	983	Shared Neighborhood Hits	110
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSK_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.052743 (rank : 1050)
Query Neighborhood Hits	458	Target Neighborhood Hits	1009	Shared Neighborhood Hits	50
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.051724 (rank : 1058)
Query Neighborhood Hits	458	Target Neighborhood Hits	1009	Shared Neighborhood Hits	50
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CSPG4_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.063368 (rank : 923)
Query Neighborhood Hits	458	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.062059 (rank : 936)
Query Neighborhood Hits	458	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CT075_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.096526 (rank : 688)
Query Neighborhood Hits	458	Target Neighborhood Hits	387	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

CT075_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.077243 (rank : 810)
Query Neighborhood Hits	458	Target Neighborhood Hits	358	Shared Neighborhood Hits	64
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

CT127_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.233741 (rank : 301)
Query Neighborhood Hits	458	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CXAR_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.095455 (rank : 693)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	52
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

CXAR_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.088207 (rank : 735)
Query Neighborhood Hits	458	Target Neighborhood Hits	250	Shared Neighborhood Hits	55
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

DDR1_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.066243 (rank : 892)
Query Neighborhood Hits	458	Target Neighborhood Hits	819	Shared Neighborhood Hits	55
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.065123 (rank : 903)
Query Neighborhood Hits	458	Target Neighborhood Hits	818	Shared Neighborhood Hits	54
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.064777 (rank : 907)
Query Neighborhood Hits	458	Target Neighborhood Hits	818	Shared Neighborhood Hits	54
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 585)	NC score	0.064054 (rank : 916)
Query Neighborhood Hits	458	Target Neighborhood Hits	813	Shared Neighborhood Hits	53
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DKK3_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.108933 (rank : 631)
Query Neighborhood Hits	458	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.108995 (rank : 630)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

EGFR_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.071429 (rank : 852)
Query Neighborhood Hits	458	Target Neighborhood Hits	927	Shared Neighborhood Hits	109
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ELTD1_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.141568 (rank : 513)
Query Neighborhood Hits	458	Target Neighborhood Hits	269	Shared Neighborhood Hits	135
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

EMB_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.076727 (rank : 817)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

EMR1_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.254832 (rank : 272)
Query Neighborhood Hits	458	Target Neighborhood Hits	382	Shared Neighborhood Hits	184
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR3_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.100062 (rank : 671)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 593)	NC score	0.071128 (rank : 856)
Query Neighborhood Hits	458	Target Neighborhood Hits	191	Shared Neighborhood Hits	90
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

EPGN_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.054123 (rank : 1037)
Query Neighborhood Hits	458	Target Neighborhood Hits	59	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EPGN_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.054574 (rank : 1024)
Query Neighborhood Hits	458	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EPHA1_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.119556 (rank : 580)
Query Neighborhood Hits	458	Target Neighborhood Hits	958	Shared Neighborhood Hits	158
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

ERBB2_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.070545 (rank : 858)
Query Neighborhood Hits	458	Target Neighborhood Hits	1073	Shared Neighborhood Hits	98
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.068456 (rank : 876)
Query Neighborhood Hits	458	Target Neighborhood Hits	918	Shared Neighborhood Hits	90
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.077571 (rank : 809)
Query Neighborhood Hits	458	Target Neighborhood Hits	918	Shared Neighborhood Hits	106
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.071860 (rank : 850)
Query Neighborhood Hits	458	Target Neighborhood Hits	898	Shared Neighborhood Hits	95
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.074278 (rank : 836)
Query Neighborhood Hits	458	Target Neighborhood Hits	910	Shared Neighborhood Hits	102
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

EREG_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.066108 (rank : 895)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	44
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESAM_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.093551 (rank : 710)
Query Neighborhood Hits	458	Target Neighborhood Hits	251	Shared Neighborhood Hits	62
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ESAM_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.088573 (rank : 734)
Query Neighborhood Hits	458	Target Neighborhood Hits	222	Shared Neighborhood Hits	54
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ESM1_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.147153 (rank : 504)
Query Neighborhood Hits	458	Target Neighborhood Hits	110	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.106113 (rank : 649)
Query Neighborhood Hits	458	Target Neighborhood Hits	107	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA10_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.123516 (rank : 561)
Query Neighborhood Hits	458	Target Neighborhood Hits	435	Shared Neighborhood Hits	170
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA7_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.105027 (rank : 656)
Query Neighborhood Hits	458	Target Neighborhood Hits	404	Shared Neighborhood Hits	158
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.086492 (rank : 744)
Query Neighborhood Hits	458	Target Neighborhood Hits	374	Shared Neighborhood Hits	136
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.110715 (rank : 617)
Query Neighborhood Hits	458	Target Neighborhood Hits	421	Shared Neighborhood Hits	159
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FAK1_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.061567 (rank : 941)
Query Neighborhood Hits	458	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.061436 (rank : 943)
Query Neighborhood Hits	458	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.062407 (rank : 931)
Query Neighborhood Hits	458	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.061939 (rank : 937)
Query Neighborhood Hits	458	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FBLN1_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.305547 (rank : 212)
Query Neighborhood Hits	458	Target Neighborhood Hits	324	Shared Neighborhood Hits	197
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.302291 (rank : 215)
Query Neighborhood Hits	458	Target Neighborhood Hits	329	Shared Neighborhood Hits	195
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN3_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.267101 (rank : 261)
Query Neighborhood Hits	458	Target Neighborhood Hits	279	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.277891 (rank : 246)
Query Neighborhood Hits	458	Target Neighborhood Hits	270	Shared Neighborhood Hits	172
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FCERA_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.052186 (rank : 1057)
Query Neighborhood Hits	458	Target Neighborhood Hits	150	Shared Neighborhood Hits	39
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

FCGR1_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.051146 (rank : 1064)
Query Neighborhood Hits	458	Target Neighborhood Hits	145	Shared Neighborhood Hits	43
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

FCN1_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.074721 (rank : 830)
Query Neighborhood Hits	458	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN1_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.075401 (rank : 825)
Query Neighborhood Hits	458	Target Neighborhood Hits	173	Shared Neighborhood Hits	14
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN2_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.075318 (rank : 826)
Query Neighborhood Hits	458	Target Neighborhood Hits	122	Shared Neighborhood Hits	13
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

FCN3_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.075737 (rank : 823)
Query Neighborhood Hits	458	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

FCRL2_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.148838 (rank : 500)
Query Neighborhood Hits	458	Target Neighborhood Hits	251	Shared Neighborhood Hits	67
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

FCRL5_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.161694 (rank : 457)
Query Neighborhood Hits	458	Target Neighborhood Hits	267	Shared Neighborhood Hits	62
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

FER_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.055841 (rank : 1001)
Query Neighborhood Hits	458	Target Neighborhood Hits	1278	Shared Neighborhood Hits	56
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FES_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.057001 (rank : 988)
Query Neighborhood Hits	458	Target Neighborhood Hits	978	Shared Neighborhood Hits	51
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.057004 (rank : 987)
Query Neighborhood Hits	458	Target Neighborhood Hits	980	Shared Neighborhood Hits	53
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FGFR1_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.123646 (rank : 559)
Query Neighborhood Hits	458	Target Neighborhood Hits	1069	Shared Neighborhood Hits	116
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.123485 (rank : 562)
Query Neighborhood Hits	458	Target Neighborhood Hits	1068	Shared Neighborhood Hits	116
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FGFR2_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.123322 (rank : 564)
Query Neighborhood Hits	458	Target Neighborhood Hits	1062	Shared Neighborhood Hits	116
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

FGFR2_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.119308 (rank : 581)
Query Neighborhood Hits	458	Target Neighborhood Hits	1062	Shared Neighborhood Hits	116
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

FGFR3_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.122789 (rank : 566)
Query Neighborhood Hits	458	Target Neighborhood Hits	1042	Shared Neighborhood Hits	116
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FGFR3_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.125638 (rank : 553)
Query Neighborhood Hits	458	Target Neighborhood Hits	1059	Shared Neighborhood Hits	118
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

FGFR4_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.126837 (rank : 551)
Query Neighborhood Hits	458	Target Neighborhood Hits	1037	Shared Neighborhood Hits	116
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FGFR4_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.129647 (rank : 539)
Query Neighborhood Hits	458	Target Neighborhood Hits	1026	Shared Neighborhood Hits	117
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FGL1_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.068434 (rank : 877)
Query Neighborhood Hits	458	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q08830, Q4PJH9, Q96KW6, Q96QM6	Gene names	FGL1, HFREP1
Domain Architecture
Description	Fibrinogen-like protein 1 precursor (Hepatocyte-derived fibrinogen- related protein 1) (HFREP-1) (Hepassocin) (HP-041).

FGL2_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.066521 (rank : 888)
Query Neighborhood Hits	458	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

FGL2_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.067671 (rank : 883)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

FGRL1_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.226080 (rank : 320)
Query Neighborhood Hits	458	Target Neighborhood Hits	335	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.225113 (rank : 322)
Query Neighborhood Hits	458	Target Neighborhood Hits	325	Shared Neighborhood Hits	80
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FGR_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.054124 (rank : 1036)
Query Neighborhood Hits	458	Target Neighborhood Hits	1067	Shared Neighborhood Hits	50
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.053996 (rank : 1038)
Query Neighborhood Hits	458	Target Neighborhood Hits	1069	Shared Neighborhood Hits	50
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FIBA_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.066416 (rank : 890)
Query Neighborhood Hits	458	Target Neighborhood Hits	132	Shared Neighborhood Hits	12
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

FIBB_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.064664 (rank : 909)
Query Neighborhood Hits	458	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

FIBB_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.064862 (rank : 904)
Query Neighborhood Hits	458	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

FIBG_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.059011 (rank : 972)
Query Neighborhood Hits	458	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P02679, P04469, P04470, Q96A14, Q96KJ3	Gene names	FGG
Domain Architecture
Description	Fibrinogen gamma chain precursor.

FIBG_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.059415 (rank : 967)
Query Neighborhood Hits	458	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM7, Q8WUR3, Q91ZP0	Gene names	Fgg
Domain Architecture	No domain graphic available
Description	Fibrinogen gamma chain precursor.

FLT3_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.064779 (rank : 906)
Query Neighborhood Hits	458	Target Neighborhood Hits	843	Shared Neighborhood Hits	65
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

FLT3_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.072379 (rank : 845)
Query Neighborhood Hits	458	Target Neighborhood Hits	847	Shared Neighborhood Hits	79
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FREM1_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.059490 (rank : 966)
Query Neighborhood Hits	458	Target Neighborhood Hits	170	Shared Neighborhood Hits	24
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.057247 (rank : 986)
Query Neighborhood Hits	458	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FRK_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.053993 (rank : 1039)
Query Neighborhood Hits	458	Target Neighborhood Hits	1058	Shared Neighborhood Hits	50
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FSTL3_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.107008 (rank : 638)
Query Neighborhood Hits	458	Target Neighborhood Hits	162	Shared Neighborhood Hits	74
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.084515 (rank : 763)
Query Neighborhood Hits	458	Target Neighborhood Hits	152	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL4_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.179773 (rank : 406)
Query Neighborhood Hits	458	Target Neighborhood Hits	344	Shared Neighborhood Hits	83
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL4_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.186119 (rank : 386)
Query Neighborhood Hits	458	Target Neighborhood Hits	333	Shared Neighborhood Hits	85
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.182385 (rank : 395)
Query Neighborhood Hits	458	Target Neighborhood Hits	347	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.178459 (rank : 410)
Query Neighborhood Hits	458	Target Neighborhood Hits	355	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FST_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.073081 (rank : 840)
Query Neighborhood Hits	458	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.076844 (rank : 813)
Query Neighborhood Hits	458	Target Neighborhood Hits	146	Shared Neighborhood Hits	59
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FYN_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.052674 (rank : 1053)
Query Neighborhood Hits	458	Target Neighborhood Hits	1078	Shared Neighborhood Hits	51
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.053258 (rank : 1049)
Query Neighborhood Hits	458	Target Neighborhood Hits	1073	Shared Neighborhood Hits	51
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GPA33_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.116237 (rank : 588)
Query Neighborhood Hits	458	Target Neighborhood Hits	273	Shared Neighborhood Hits	60
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

GPA33_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.113472 (rank : 598)
Query Neighborhood Hits	458	Target Neighborhood Hits	294	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

GUC2C_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.050929 (rank : 1065)
Query Neighborhood Hits	458	Target Neighborhood Hits	624	Shared Neighborhood Hits	42
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2F_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.050474 (rank : 1068)
Query Neighborhood Hits	458	Target Neighborhood Hits	740	Shared Neighborhood Hits	49
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

HCK_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.055172 (rank : 1010)
Query Neighborhood Hits	458	Target Neighborhood Hits	1035	Shared Neighborhood Hits	51
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.055480 (rank : 1006)
Query Neighborhood Hits	458	Target Neighborhood Hits	1029	Shared Neighborhood Hits	50
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HGFA_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.122061 (rank : 568)
Query Neighborhood Hits	458	Target Neighborhood Hits	436	Shared Neighborhood Hits	173
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.117472 (rank : 582)
Query Neighborhood Hits	458	Target Neighborhood Hits	419	Shared Neighborhood Hits	173
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HHLA2_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.055090 (rank : 1014)
Query Neighborhood Hits	458	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

I11RA_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.053380 (rank : 1047)
Query Neighborhood Hits	458	Target Neighborhood Hits	138	Shared Neighborhood Hits	44
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

I11RA_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.054347 (rank : 1028)
Query Neighborhood Hits	458	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

I11RB_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.062063 (rank : 935)
Query Neighborhood Hits	458	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

I12R1_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.115548 (rank : 591)
Query Neighborhood Hits	458	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I12R1_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.109137 (rank : 628)
Query Neighborhood Hits	458	Target Neighborhood Hits	70	Shared Neighborhood Hits	53
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

I12R2_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.212754 (rank : 345)
Query Neighborhood Hits	458	Target Neighborhood Hits	143	Shared Neighborhood Hits	103
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

IBP7_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.165472 (rank : 445)
Query Neighborhood Hits	458	Target Neighborhood Hits	220	Shared Neighborhood Hits	76
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.166129 (rank : 443)
Query Neighborhood Hits	458	Target Neighborhood Hits	230	Shared Neighborhood Hits	83
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ICAM5_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.175399 (rank : 421)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

ICAM5_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.180908 (rank : 402)
Query Neighborhood Hits	458	Target Neighborhood Hits	308	Shared Neighborhood Hits	73
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

IGS21_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.082736 (rank : 774)
Query Neighborhood Hits	458	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS21_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.078742 (rank : 802)
Query Neighborhood Hits	458	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS4B_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.136086 (rank : 528)
Query Neighborhood Hits	458	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

IGS4B_MOUSE
θ value	θ > 10 (rank : 687)	NC score	0.137748 (rank : 522)
Query Neighborhood Hits	458	Target Neighborhood Hits	328	Shared Neighborhood Hits	67
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IL1R1_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.070481 (rank : 861)
Query Neighborhood Hits	458	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

IL1R1_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.070483 (rank : 860)
Query Neighborhood Hits	458	Target Neighborhood Hits	142	Shared Neighborhood Hits	53
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

IL1R2_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.113746 (rank : 597)
Query Neighborhood Hits	458	Target Neighborhood Hits	153	Shared Neighborhood Hits	53
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

IL1R2_MOUSE
θ value	θ > 10 (rank : 691)	NC score	0.094755 (rank : 700)
Query Neighborhood Hits	458	Target Neighborhood Hits	125	Shared Neighborhood Hits	44
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

ILK1_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.060537 (rank : 951)
Query Neighborhood Hits	458	Target Neighborhood Hits	857	Shared Neighborhood Hits	57
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.060424 (rank : 957)
Query Neighborhood Hits	458	Target Neighborhood Hits	848	Shared Neighborhood Hits	56
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
θ value	θ > 10 (rank : 694)	NC score	0.060458 (rank : 954)
Query Neighborhood Hits	458	Target Neighborhood Hits	858	Shared Neighborhood Hits	56
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ILRL1_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.064129 (rank : 915)
Query Neighborhood Hits	458	Target Neighborhood Hits	167	Shared Neighborhood Hits	47
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

ILRL2_MOUSE
θ value	θ > 10 (rank : 696)	NC score	0.076006 (rank : 822)
Query Neighborhood Hits	458	Target Neighborhood Hits	158	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

IRPL1_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.081101 (rank : 789)
Query Neighborhood Hits	458	Target Neighborhood Hits	196	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

IRPL1_MOUSE
θ value	θ > 10 (rank : 698)	NC score	0.087389 (rank : 742)
Query Neighborhood Hits	458	Target Neighborhood Hits	186	Shared Neighborhood Hits	60
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

IRPL2_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.091393 (rank : 722)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

IRPL2_MOUSE
θ value	θ > 10 (rank : 700)	NC score	0.091147 (rank : 724)
Query Neighborhood Hits	458	Target Neighborhood Hits	195	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

ITK_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.055017 (rank : 1017)
Query Neighborhood Hits	458	Target Neighborhood Hits	1016	Shared Neighborhood Hits	53
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 702)	NC score	0.055111 (rank : 1012)
Query Neighborhood Hits	458	Target Neighborhood Hits	985	Shared Neighborhood Hits	53
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

JAK1_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.051191 (rank : 1063)
Query Neighborhood Hits	458	Target Neighborhood Hits	858	Shared Neighborhood Hits	50
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.051274 (rank : 1061)
Query Neighborhood Hits	458	Target Neighborhood Hits	854	Shared Neighborhood Hits	50
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAM1_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.167633 (rank : 441)
Query Neighborhood Hits	458	Target Neighborhood Hits	294	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JAM1_MOUSE
θ value	θ > 10 (rank : 706)	NC score	0.161563 (rank : 458)
Query Neighborhood Hits	458	Target Neighborhood Hits	287	Shared Neighborhood Hits	72
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

JAM2_MOUSE
θ value	θ > 10 (rank : 707)	NC score	0.141123 (rank : 514)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM3_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.171444 (rank : 426)
Query Neighborhood Hits	458	Target Neighborhood Hits	271	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAM3_MOUSE
θ value	θ > 10 (rank : 709)	NC score	0.168967 (rank : 435)
Query Neighborhood Hits	458	Target Neighborhood Hits	286	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAML1_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.062963 (rank : 927)
Query Neighborhood Hits	458	Target Neighborhood Hits	185	Shared Neighborhood Hits	40
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

KALM_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.192840 (rank : 374)
Query Neighborhood Hits	458	Target Neighborhood Hits	114	Shared Neighborhood Hits	82
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

KAZD1_HUMAN
θ value	θ > 10 (rank : 712)	NC score	0.184548 (rank : 389)
Query Neighborhood Hits	458	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 713)	NC score	0.185175 (rank : 387)
Query Neighborhood Hits	458	Target Neighborhood Hits	281	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KIRR1_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.159162 (rank : 467)
Query Neighborhood Hits	458	Target Neighborhood Hits	401	Shared Neighborhood Hits	70
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR1_MOUSE
θ value	θ > 10 (rank : 715)	NC score	0.157599 (rank : 472)
Query Neighborhood Hits	458	Target Neighborhood Hits	403	Shared Neighborhood Hits	70
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR2_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.179242 (rank : 408)
Query Neighborhood Hits	458	Target Neighborhood Hits	321	Shared Neighborhood Hits	70
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

KIRR2_MOUSE
θ value	θ > 10 (rank : 717)	NC score	0.177979 (rank : 412)
Query Neighborhood Hits	458	Target Neighborhood Hits	326	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

KIRR3_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.160606 (rank : 463)
Query Neighborhood Hits	458	Target Neighborhood Hits	302	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

KIRR3_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.157035 (rank : 475)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

KIT_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.093460 (rank : 711)
Query Neighborhood Hits	458	Target Neighborhood Hits	953	Shared Neighborhood Hits	107
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 721)	NC score	0.097831 (rank : 679)
Query Neighborhood Hits	458	Target Neighborhood Hits	949	Shared Neighborhood Hits	106
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KR101_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.281889 (rank : 240)
Query Neighborhood Hits	458	Target Neighborhood Hits	261	Shared Neighborhood Hits	144
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.253006 (rank : 275)
Query Neighborhood Hits	458	Target Neighborhood Hits	264	Shared Neighborhood Hits	138
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.155483 (rank : 483)
Query Neighborhood Hits	458	Target Neighborhood Hits	212	Shared Neighborhood Hits	108
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR104_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.344610 (rank : 167)
Query Neighborhood Hits	458	Target Neighborhood Hits	313	Shared Neighborhood Hits	168
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.233328 (rank : 303)
Query Neighborhood Hits	458	Target Neighborhood Hits	271	Shared Neighborhood Hits	147
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.319132 (rank : 196)
Query Neighborhood Hits	458	Target Neighborhood Hits	347	Shared Neighborhood Hits	173
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.330116 (rank : 179)
Query Neighborhood Hits	458	Target Neighborhood Hits	330	Shared Neighborhood Hits	175
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.217866 (rank : 337)
Query Neighborhood Hits	458	Target Neighborhood Hits	226	Shared Neighborhood Hits	126
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.219783 (rank : 332)
Query Neighborhood Hits	458	Target Neighborhood Hits	226	Shared Neighborhood Hits	125
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.149360 (rank : 497)
Query Neighborhood Hits	458	Target Neighborhood Hits	232	Shared Neighborhood Hits	120
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.206022 (rank : 355)
Query Neighborhood Hits	458	Target Neighborhood Hits	269	Shared Neighborhood Hits	137
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.219190 (rank : 334)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	125
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.391835 (rank : 117)
Query Neighborhood Hits	458	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.113182 (rank : 600)
Query Neighborhood Hits	458	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.169514 (rank : 433)
Query Neighborhood Hits	458	Target Neighborhood Hits	178	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.091474 (rank : 721)
Query Neighborhood Hits	458	Target Neighborhood Hits	112	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.180779 (rank : 404)
Query Neighborhood Hits	458	Target Neighborhood Hits	199	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.434557 (rank : 69)
Query Neighborhood Hits	458	Target Neighborhood Hits	217	Shared Neighborhood Hits	130
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.393207 (rank : 114)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	132
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.192371 (rank : 375)
Query Neighborhood Hits	458	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.196797 (rank : 366)
Query Neighborhood Hits	458	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.151712 (rank : 492)
Query Neighborhood Hits	458	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.088078 (rank : 736)
Query Neighborhood Hits	458	Target Neighborhood Hits	192	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.119920 (rank : 578)
Query Neighborhood Hits	458	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.195313 (rank : 369)
Query Neighborhood Hits	458	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.194408 (rank : 372)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.200680 (rank : 360)
Query Neighborhood Hits	458	Target Neighborhood Hits	204	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA55_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.459383 (rank : 60)
Query Neighborhood Hits	458	Target Neighborhood Hits	257	Shared Neighborhood Hits	155
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA92_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.184805 (rank : 388)
Query Neighborhood Hits	458	Target Neighborhood Hits	198	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.199382 (rank : 364)
Query Neighborhood Hits	458	Target Neighborhood Hits	203	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 752)	NC score	0.190849 (rank : 381)
Query Neighborhood Hits	458	Target Neighborhood Hits	204	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.191740 (rank : 377)
Query Neighborhood Hits	458	Target Neighborhood Hits	185	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.173838 (rank : 424)
Query Neighborhood Hits	458	Target Neighborhood Hits	173	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KSYK_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.058601 (rank : 974)
Query Neighborhood Hits	458	Target Neighborhood Hits	901	Shared Neighborhood Hits	51
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.058592 (rank : 976)
Query Neighborhood Hits	458	Target Neighborhood Hits	944	Shared Neighborhood Hits	51
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LCE1A_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.148665 (rank : 501)
Query Neighborhood Hits	458	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.183973 (rank : 391)
Query Neighborhood Hits	458	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.182656 (rank : 394)
Query Neighborhood Hits	458	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.160988 (rank : 459)
Query Neighborhood Hits	458	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.158792 (rank : 469)
Query Neighborhood Hits	458	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.151688 (rank : 493)
Query Neighborhood Hits	458	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.074645 (rank : 831)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.074476 (rank : 835)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 765)	NC score	0.087147 (rank : 743)
Query Neighborhood Hits	458	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.080667 (rank : 793)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.133479 (rank : 531)
Query Neighborhood Hits	458	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.059239 (rank : 969)
Query Neighborhood Hits	458	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE3C_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.053354 (rank : 1048)
Query Neighborhood Hits	458	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE4A_HUMAN
θ value	θ > 10 (rank : 770)	NC score	0.121487 (rank : 572)
Query Neighborhood Hits	458	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.058593 (rank : 975)
Query Neighborhood Hits	458	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LCK_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.055152 (rank : 1011)
Query Neighborhood Hits	458	Target Neighborhood Hits	987	Shared Neighborhood Hits	52
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.055104 (rank : 1013)
Query Neighborhood Hits	458	Target Neighborhood Hits	981	Shared Neighborhood Hits	50
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LDLR_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.244096 (rank : 289)
Query Neighborhood Hits	458	Target Neighborhood Hits	375	Shared Neighborhood Hits	205
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 775)	NC score	0.223090 (rank : 328)
Query Neighborhood Hits	458	Target Neighborhood Hits	382	Shared Neighborhood Hits	199
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LEPR_MOUSE
θ value	θ > 10 (rank : 776)	NC score	0.059013 (rank : 971)
Query Neighborhood Hits	458	Target Neighborhood Hits	109	Shared Neighborhood Hits	53
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

LIFR_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.212213 (rank : 347)
Query Neighborhood Hits	458	Target Neighborhood Hits	130	Shared Neighborhood Hits	86
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

LORI_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.106835 (rank : 640)
Query Neighborhood Hits	458	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRC21_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.115925 (rank : 590)
Query Neighborhood Hits	458	Target Neighborhood Hits	456	Shared Neighborhood Hits	94
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC24_HUMAN
θ value	θ > 10 (rank : 780)	NC score	0.079118 (rank : 800)
Query Neighborhood Hits	458	Target Neighborhood Hits	404	Shared Neighborhood Hits	75
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC24_MOUSE
θ value	θ > 10 (rank : 781)	NC score	0.069602 (rank : 868)
Query Neighborhood Hits	458	Target Neighborhood Hits	387	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC4B_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.066301 (rank : 891)
Query Neighborhood Hits	458	Target Neighborhood Hits	479	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRC4B_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.067481 (rank : 885)
Query Neighborhood Hits	458	Target Neighborhood Hits	484	Shared Neighborhood Hits	71
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRFN2_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.109309 (rank : 625)
Query Neighborhood Hits	458	Target Neighborhood Hits	450	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_MOUSE
θ value	θ > 10 (rank : 785)	NC score	0.111253 (rank : 611)
Query Neighborhood Hits	458	Target Neighborhood Hits	450	Shared Neighborhood Hits	84
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN3_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.102989 (rank : 662)
Query Neighborhood Hits	458	Target Neighborhood Hits	444	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
θ value	θ > 10 (rank : 787)	NC score	0.108085 (rank : 634)
Query Neighborhood Hits	458	Target Neighborhood Hits	455	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN4_HUMAN
θ value	θ > 10 (rank : 788)	NC score	0.116615 (rank : 584)
Query Neighborhood Hits	458	Target Neighborhood Hits	462	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN4_MOUSE
θ value	θ > 10 (rank : 789)	NC score	0.112294 (rank : 608)
Query Neighborhood Hits	458	Target Neighborhood Hits	442	Shared Neighborhood Hits	86
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN5_HUMAN
θ value	θ > 10 (rank : 790)	NC score	0.096364 (rank : 689)
Query Neighborhood Hits	458	Target Neighborhood Hits	464	Shared Neighborhood Hits	78
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN5_MOUSE
θ value	θ > 10 (rank : 791)	NC score	0.098391 (rank : 677)
Query Neighborhood Hits	458	Target Neighborhood Hits	472	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRIG1_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.165097 (rank : 450)
Query Neighborhood Hits	458	Target Neighborhood Hits	654	Shared Neighborhood Hits	88
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
θ value	θ > 10 (rank : 793)	NC score	0.163265 (rank : 451)
Query Neighborhood Hits	458	Target Neighborhood Hits	627	Shared Neighborhood Hits	88
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.165363 (rank : 447)
Query Neighborhood Hits	458	Target Neighborhood Hits	595	Shared Neighborhood Hits	89
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
θ value	θ > 10 (rank : 795)	NC score	0.165221 (rank : 449)
Query Neighborhood Hits	458	Target Neighborhood Hits	586	Shared Neighborhood Hits	90
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG3_HUMAN
θ value	θ > 10 (rank : 796)	NC score	0.159724 (rank : 466)
Query Neighborhood Hits	458	Target Neighborhood Hits	601	Shared Neighborhood Hits	91
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRIG3_MOUSE
θ value	θ > 10 (rank : 797)	NC score	0.160702 (rank : 461)
Query Neighborhood Hits	458	Target Neighborhood Hits	611	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

LRP10_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.063419 (rank : 920)
Query Neighborhood Hits	458	Target Neighborhood Hits	197	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 799)	NC score	0.056238 (rank : 995)
Query Neighborhood Hits	458	Target Neighborhood Hits	169	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.053410 (rank : 1046)
Query Neighborhood Hits	458	Target Neighborhood Hits	205	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 801)	NC score	0.050758 (rank : 1067)
Query Neighborhood Hits	458	Target Neighborhood Hits	180	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 802)	NC score	0.063704 (rank : 918)
Query Neighborhood Hits	458	Target Neighborhood Hits	280	Shared Neighborhood Hits	90
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.203079 (rank : 358)
Query Neighborhood Hits	458	Target Neighborhood Hits	355	Shared Neighborhood Hits	189
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP5_HUMAN
θ value	θ > 10 (rank : 804)	NC score	0.082377 (rank : 777)
Query Neighborhood Hits	458	Target Neighborhood Hits	224	Shared Neighborhood Hits	96
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 805)	NC score	0.084799 (rank : 762)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	100
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.091727 (rank : 720)
Query Neighborhood Hits	458	Target Neighborhood Hits	235	Shared Neighborhood Hits	103
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 807)	NC score	0.087517 (rank : 741)
Query Neighborhood Hits	458	Target Neighborhood Hits	232	Shared Neighborhood Hits	99
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.199697 (rank : 362)
Query Neighborhood Hits	458	Target Neighborhood Hits	346	Shared Neighborhood Hits	179
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 809)	NC score	0.223652 (rank : 326)
Query Neighborhood Hits	458	Target Neighborhood Hits	385	Shared Neighborhood Hits	193
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRRC4_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.062251 (rank : 933)
Query Neighborhood Hits	458	Target Neighborhood Hits	444	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

LRRC4_MOUSE
θ value	θ > 10 (rank : 811)	NC score	0.053542 (rank : 1043)
Query Neighborhood Hits	458	Target Neighborhood Hits	412	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

LRRN1_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.098165 (rank : 678)
Query Neighborhood Hits	458	Target Neighborhood Hits	518	Shared Neighborhood Hits	93
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN1_MOUSE
θ value	θ > 10 (rank : 813)	NC score	0.095012 (rank : 699)
Query Neighborhood Hits	458	Target Neighborhood Hits	508	Shared Neighborhood Hits	92
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN3_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.090799 (rank : 729)
Query Neighborhood Hits	458	Target Neighborhood Hits	461	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN3_MOUSE
θ value	θ > 10 (rank : 815)	NC score	0.085415 (rank : 754)
Query Neighborhood Hits	458	Target Neighborhood Hits	455	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN5_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.082780 (rank : 773)
Query Neighborhood Hits	458	Target Neighborhood Hits	493	Shared Neighborhood Hits	80
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

LSAMP_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.191090 (rank : 380)
Query Neighborhood Hits	458	Target Neighborhood Hits	347	Shared Neighborhood Hits	75
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
θ value	θ > 10 (rank : 818)	NC score	0.191986 (rank : 376)
Query Neighborhood Hits	458	Target Neighborhood Hits	344	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

LTK_HUMAN
θ value	θ > 10 (rank : 819)	NC score	0.070193 (rank : 864)
Query Neighborhood Hits	458	Target Neighborhood Hits	774	Shared Neighborhood Hits	53
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 820)	NC score	0.070357 (rank : 862)
Query Neighborhood Hits	458	Target Neighborhood Hits	770	Shared Neighborhood Hits	54
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LU_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.175808 (rank : 419)
Query Neighborhood Hits	458	Target Neighborhood Hits	283	Shared Neighborhood Hits	75
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

LYAM1_HUMAN
θ value	θ > 10 (rank : 822)	NC score	0.141735 (rank : 512)
Query Neighborhood Hits	458	Target Neighborhood Hits	315	Shared Neighborhood Hits	151
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.170099 (rank : 430)
Query Neighborhood Hits	458	Target Neighborhood Hits	394	Shared Neighborhood Hits	183
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.191328 (rank : 378)
Query Neighborhood Hits	458	Target Neighborhood Hits	420	Shared Neighborhood Hits	195
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.139531 (rank : 519)
Query Neighborhood Hits	458	Target Neighborhood Hits	378	Shared Neighborhood Hits	171
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.159824 (rank : 465)
Query Neighborhood Hits	458	Target Neighborhood Hits	390	Shared Neighborhood Hits	169
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYN_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.054143 (rank : 1035)
Query Neighborhood Hits	458	Target Neighborhood Hits	1022	Shared Neighborhood Hits	50
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.054255 (rank : 1031)
Query Neighborhood Hits	458	Target Neighborhood Hits	1023	Shared Neighborhood Hits	50
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MAG_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.181544 (rank : 400)
Query Neighborhood Hits	458	Target Neighborhood Hits	278	Shared Neighborhood Hits	76
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.181458 (rank : 401)
Query Neighborhood Hits	458	Target Neighborhood Hits	271	Shared Neighborhood Hits	76
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MALT1_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.195998 (rank : 368)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MAMC1_HUMAN
θ value	θ > 10 (rank : 832)	NC score	0.229389 (rank : 314)
Query Neighborhood Hits	458	Target Neighborhood Hits	357	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 833)	NC score	0.230118 (rank : 311)
Query Neighborhood Hits	458	Target Neighborhood Hits	357	Shared Neighborhood Hits	83
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MATK_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.055979 (rank : 998)
Query Neighborhood Hits	458	Target Neighborhood Hits	954	Shared Neighborhood Hits	50
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 835)	NC score	0.055737 (rank : 1003)
Query Neighborhood Hits	458	Target Neighborhood Hits	952	Shared Neighborhood Hits	50
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MATN1_HUMAN
θ value	θ > 10 (rank : 836)	NC score	0.079920 (rank : 797)
Query Neighborhood Hits	458	Target Neighborhood Hits	191	Shared Neighborhood Hits	86
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 837)	NC score	0.079110 (rank : 801)
Query Neighborhood Hits	458	Target Neighborhood Hits	186	Shared Neighborhood Hits	83
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_MOUSE
θ value	θ > 10 (rank : 838)	NC score	0.287939 (rank : 229)
Query Neighborhood Hits	458	Target Neighborhood Hits	356	Shared Neighborhood Hits	184
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.231224 (rank : 306)
Query Neighborhood Hits	458	Target Neighborhood Hits	268	Shared Neighborhood Hits	150
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 840)	NC score	0.229825 (rank : 313)
Query Neighborhood Hits	458	Target Neighborhood Hits	261	Shared Neighborhood Hits	154
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 841)	NC score	0.208251 (rank : 353)
Query Neighborhood Hits	458	Target Neighborhood Hits	287	Shared Neighborhood Hits	165
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 842)	NC score	0.196647 (rank : 367)
Query Neighborhood Hits	458	Target Neighborhood Hits	277	Shared Neighborhood Hits	161
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCSP_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.076864 (rank : 812)
Query Neighborhood Hits	458	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MDGA1_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.229844 (rank : 312)
Query Neighborhood Hits	458	Target Neighborhood Hits	358	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MEP1A_HUMAN
θ value	θ > 10 (rank : 845)	NC score	0.074524 (rank : 834)
Query Neighborhood Hits	458	Target Neighborhood Hits	162	Shared Neighborhood Hits	95
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 846)	NC score	0.081300 (rank : 788)
Query Neighborhood Hits	458	Target Neighborhood Hits	166	Shared Neighborhood Hits	101
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_MOUSE
θ value	θ > 10 (rank : 847)	NC score	0.050216 (rank : 1069)
Query Neighborhood Hits	458	Target Neighborhood Hits	127	Shared Neighborhood Hits	68
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MERTK_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.140318 (rank : 517)
Query Neighborhood Hits	458	Target Neighborhood Hits	988	Shared Neighborhood Hits	126
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	θ > 10 (rank : 849)	NC score	0.138107 (rank : 521)
Query Neighborhood Hits	458	Target Neighborhood Hits	974	Shared Neighborhood Hits	131
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MET_HUMAN
θ value	θ > 10 (rank : 850)	NC score	0.060470 (rank : 953)
Query Neighborhood Hits	458	Target Neighborhood Hits	831	Shared Neighborhood Hits	50
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 851)	NC score	0.060764 (rank : 949)
Query Neighborhood Hits	458	Target Neighborhood Hits	844	Shared Neighborhood Hits	55
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MFA3L_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.153513 (rank : 487)
Query Neighborhood Hits	458	Target Neighborhood Hits	230	Shared Neighborhood Hits	72
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

MFA3L_MOUSE
θ value	θ > 10 (rank : 853)	NC score	0.131092 (rank : 536)
Query Neighborhood Hits	458	Target Neighborhood Hits	214	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

MFAP4_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.074859 (rank : 828)
Query Neighborhood Hits	458	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_MOUSE
θ value	θ > 10 (rank : 855)	NC score	0.074989 (rank : 827)
Query Neighborhood Hits	458	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFGM_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.092269 (rank : 716)
Query Neighborhood Hits	458	Target Neighborhood Hits	150	Shared Neighborhood Hits	94
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MKS3_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.075420 (rank : 824)
Query Neighborhood Hits	458	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MKS3_MOUSE
θ value	θ > 10 (rank : 858)	NC score	0.084020 (rank : 764)
Query Neighborhood Hits	458	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MLKL_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.050111 (rank : 1071)
Query Neighborhood Hits	458	Target Neighborhood Hits	600	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MMRN1_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.103471 (rank : 660)
Query Neighborhood Hits	458	Target Neighborhood Hits	636	Shared Neighborhood Hits	121
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MOX2R_MOUSE
θ value	θ > 10 (rank : 861)	NC score	0.076423 (rank : 819)
Query Neighborhood Hits	458	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

MT1A_HUMAN
θ value	θ > 10 (rank : 862)	NC score	0.169672 (rank : 432)
Query Neighborhood Hits	458	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 863)	NC score	0.182282 (rank : 396)
Query Neighborhood Hits	458	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1E_HUMAN
θ value	θ > 10 (rank : 864)	NC score	0.116582 (rank : 586)
Query Neighborhood Hits	458	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1F_HUMAN
θ value	θ > 10 (rank : 865)	NC score	0.140748 (rank : 516)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	41
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1G_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.065601 (rank : 898)
Query Neighborhood Hits	458	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1H_HUMAN
θ value	θ > 10 (rank : 867)	NC score	0.162159 (rank : 455)
Query Neighborhood Hits	458	Target Neighborhood Hits	78	Shared Neighborhood Hits	45
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1I_HUMAN
θ value	θ > 10 (rank : 868)	NC score	0.123745 (rank : 557)
Query Neighborhood Hits	458	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

MT1L_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.116585 (rank : 585)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1M_HUMAN
θ value	θ > 10 (rank : 870)	NC score	0.123972 (rank : 556)
Query Neighborhood Hits	458	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MT1X_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.106484 (rank : 646)
Query Neighborhood Hits	458	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 872)	NC score	0.136340 (rank : 527)
Query Neighborhood Hits	458	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.106666 (rank : 643)
Query Neighborhood Hits	458	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MT2_MOUSE
θ value	θ > 10 (rank : 874)	NC score	0.194947 (rank : 370)
Query Neighborhood Hits	458	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.282563 (rank : 238)
Query Neighborhood Hits	458	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 876)	NC score	0.320618 (rank : 194)
Query Neighborhood Hits	458	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.194563 (rank : 371)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 878)	NC score	0.217772 (rank : 338)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_HUMAN
θ value	θ > 10 (rank : 879)	NC score	0.087675 (rank : 740)
Query Neighborhood Hits	458	Target Neighborhood Hits	164	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC13_MOUSE
θ value	θ > 10 (rank : 880)	NC score	0.154070 (rank : 485)
Query Neighborhood Hits	458	Target Neighborhood Hits	447	Shared Neighborhood Hits	143
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC18_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.176699 (rank : 416)
Query Neighborhood Hits	458	Target Neighborhood Hits	275	Shared Neighborhood Hits	71
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

MUC18_MOUSE
θ value	θ > 10 (rank : 882)	NC score	0.166113 (rank : 444)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

MUSK_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.165457 (rank : 446)
Query Neighborhood Hits	458	Target Neighborhood Hits	1074	Shared Neighborhood Hits	118
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 884)	NC score	0.165267 (rank : 448)
Query Neighborhood Hits	458	Target Neighborhood Hits	1057	Shared Neighborhood Hits	118
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MYOTI_HUMAN
θ value	θ > 10 (rank : 885)	NC score	0.224353 (rank : 324)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYOTI_MOUSE
θ value	θ > 10 (rank : 886)	NC score	0.226878 (rank : 319)
Query Neighborhood Hits	458	Target Neighborhood Hits	297	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYPC2_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.272138 (rank : 254)
Query Neighborhood Hits	458	Target Neighborhood Hits	297	Shared Neighborhood Hits	111
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MYPN_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.227995 (rank : 318)
Query Neighborhood Hits	458	Target Neighborhood Hits	418	Shared Neighborhood Hits	85
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYPN_MOUSE
θ value	θ > 10 (rank : 889)	NC score	0.223363 (rank : 327)
Query Neighborhood Hits	458	Target Neighborhood Hits	421	Shared Neighborhood Hits	84
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NCA11_HUMAN
θ value	θ > 10 (rank : 890)	NC score	0.249557 (rank : 279)
Query Neighborhood Hits	458	Target Neighborhood Hits	443	Shared Neighborhood Hits	122
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA11_MOUSE
θ value	θ > 10 (rank : 891)	NC score	0.247991 (rank : 283)
Query Neighborhood Hits	458	Target Neighborhood Hits	661	Shared Neighborhood Hits	131
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.239604 (rank : 294)
Query Neighborhood Hits	458	Target Neighborhood Hits	437	Shared Neighborhood Hits	117
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NCA12_MOUSE
θ value	θ > 10 (rank : 893)	NC score	0.242812 (rank : 290)
Query Neighborhood Hits	458	Target Neighborhood Hits	399	Shared Neighborhood Hits	109
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

NEGR1_HUMAN
θ value	θ > 10 (rank : 894)	NC score	0.191259 (rank : 379)
Query Neighborhood Hits	458	Target Neighborhood Hits	346	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

NEGR1_MOUSE
θ value	θ > 10 (rank : 895)	NC score	0.189965 (rank : 382)
Query Neighborhood Hits	458	Target Neighborhood Hits	349	Shared Neighborhood Hits	74
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

NFX1_HUMAN
θ value	θ > 10 (rank : 896)	NC score	0.158799 (rank : 468)
Query Neighborhood Hits	458	Target Neighborhood Hits	405	Shared Neighborhood Hits	114
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NGL1_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.064516 (rank : 911)
Query Neighborhood Hits	458	Target Neighborhood Hits	511	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_MOUSE
θ value	θ > 10 (rank : 898)	NC score	0.064633 (rank : 910)
Query Neighborhood Hits	458	Target Neighborhood Hits	512	Shared Neighborhood Hits	72
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NPTN_HUMAN
θ value	θ > 10 (rank : 899)	NC score	0.181675 (rank : 398)
Query Neighborhood Hits	458	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NPTN_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.168920 (rank : 436)
Query Neighborhood Hits	458	Target Neighborhood Hits	216	Shared Neighborhood Hits	68
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NRG1_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.181576 (rank : 399)
Query Neighborhood Hits	458	Target Neighborhood Hits	285	Shared Neighborhood Hits	133
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 902)	NC score	0.212674 (rank : 346)
Query Neighborhood Hits	458	Target Neighborhood Hits	419	Shared Neighborhood Hits	150
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 903)	NC score	0.224075 (rank : 325)
Query Neighborhood Hits	458	Target Neighborhood Hits	392	Shared Neighborhood Hits	166
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG4_HUMAN
θ value	θ > 10 (rank : 904)	NC score	0.076841 (rank : 814)
Query Neighborhood Hits	458	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 905)	NC score	0.073014 (rank : 842)
Query Neighborhood Hits	458	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRX1A_MOUSE
θ value	θ > 10 (rank : 906)	NC score	0.129643 (rank : 540)
Query Neighborhood Hits	458	Target Neighborhood Hits	164	Shared Neighborhood Hits	102
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NTRI_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.180659 (rank : 405)
Query Neighborhood Hits	458	Target Neighborhood Hits	344	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NTRI_MOUSE
θ value	θ > 10 (rank : 908)	NC score	0.182687 (rank : 393)
Query Neighborhood Hits	458	Target Neighborhood Hits	342	Shared Neighborhood Hits	76
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NTRK1_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.082181 (rank : 782)
Query Neighborhood Hits	458	Target Neighborhood Hits	1023	Shared Neighborhood Hits	104
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.109140 (rank : 627)
Query Neighborhood Hits	458	Target Neighborhood Hits	1081	Shared Neighborhood Hits	118
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.108273 (rank : 632)
Query Neighborhood Hits	458	Target Neighborhood Hits	1088	Shared Neighborhood Hits	119
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.109251 (rank : 626)
Query Neighborhood Hits	458	Target Neighborhood Hits	1115	Shared Neighborhood Hits	122
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

OBSCN_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.125147 (rank : 554)
Query Neighborhood Hits	458	Target Neighborhood Hits	1931	Shared Neighborhood Hits	159
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OBSL1_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.241261 (rank : 293)
Query Neighborhood Hits	458	Target Neighborhood Hits	354	Shared Neighborhood Hits	79
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

ODFP_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.052544 (rank : 1055)
Query Neighborhood Hits	458	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

OPCM_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.188077 (rank : 384)
Query Neighborhood Hits	458	Target Neighborhood Hits	332	Shared Neighborhood Hits	77
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

PCSK5_HUMAN
θ value	θ > 10 (rank : 917)	NC score	0.156557 (rank : 479)
Query Neighborhood Hits	458	Target Neighborhood Hits	291	Shared Neighborhood Hits	150
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.111167 (rank : 612)
Query Neighborhood Hits	458	Target Neighborhood Hits	298	Shared Neighborhood Hits	132
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PDL1_HUMAN
θ value	θ > 10 (rank : 919)	NC score	0.078182 (rank : 805)
Query Neighborhood Hits	458	Target Neighborhood Hits	195	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 920)	NC score	0.059171 (rank : 970)
Query Neighborhood Hits	458	Target Neighborhood Hits	168	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_MOUSE
θ value	θ > 10 (rank : 921)	NC score	0.065472 (rank : 901)
Query Neighborhood Hits	458	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PECA1_HUMAN
θ value	θ > 10 (rank : 922)	NC score	0.072784 (rank : 844)
Query Neighborhood Hits	458	Target Neighborhood Hits	178	Shared Neighborhood Hits	48
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

PECA1_MOUSE
θ value	θ > 10 (rank : 923)	NC score	0.056586 (rank : 991)
Query Neighborhood Hits	458	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

PERT_HUMAN
θ value	θ > 10 (rank : 924)	NC score	0.095195 (rank : 698)
Query Neighborhood Hits	458	Target Neighborhood Hits	221	Shared Neighborhood Hits	103
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 925)	NC score	0.085703 (rank : 751)
Query Neighborhood Hits	458	Target Neighborhood Hits	221	Shared Neighborhood Hits	97
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGCA_HUMAN
θ value	θ > 10 (rank : 926)	NC score	0.099570 (rank : 673)
Query Neighborhood Hits	458	Target Neighborhood Hits	821	Shared Neighborhood Hits	167
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCB_HUMAN
θ value	θ > 10 (rank : 927)	NC score	0.121450 (rank : 573)
Query Neighborhood Hits	458	Target Neighborhood Hits	478	Shared Neighborhood Hits	152
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 928)	NC score	0.127947 (rank : 548)
Query Neighborhood Hits	458	Target Neighborhood Hits	459	Shared Neighborhood Hits	155
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGFRA_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.100334 (rank : 670)
Query Neighborhood Hits	458	Target Neighborhood Hits	980	Shared Neighborhood Hits	110
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
θ value	θ > 10 (rank : 930)	NC score	0.100656 (rank : 668)
Query Neighborhood Hits	458	Target Neighborhood Hits	975	Shared Neighborhood Hits	111
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_HUMAN
θ value	θ > 10 (rank : 931)	NC score	0.090730 (rank : 730)
Query Neighborhood Hits	458	Target Neighborhood Hits	962	Shared Neighborhood Hits	110
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
θ value	θ > 10 (rank : 932)	NC score	0.095353 (rank : 694)
Query Neighborhood Hits	458	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRL_HUMAN
θ value	θ > 10 (rank : 933)	NC score	0.069225 (rank : 869)
Query Neighborhood Hits	458	Target Neighborhood Hits	115	Shared Neighborhood Hits	46
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PGFRL_MOUSE
θ value	θ > 10 (rank : 934)	NC score	0.051263 (rank : 1062)
Query Neighborhood Hits	458	Target Neighborhood Hits	106	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

PGH1_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.066204 (rank : 893)
Query Neighborhood Hits	458	Target Neighborhood Hits	91	Shared Neighborhood Hits	58
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_MOUSE
θ value	θ > 10 (rank : 936)	NC score	0.078410 (rank : 804)
Query Neighborhood Hits	458	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.083310 (rank : 768)
Query Neighborhood Hits	458	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 938)	NC score	0.090827 (rank : 727)
Query Neighborhood Hits	458	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PIGR_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.082110 (rank : 783)
Query Neighborhood Hits	458	Target Neighborhood Hits	164	Shared Neighborhood Hits	47
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

PIGR_MOUSE
θ value	θ > 10 (rank : 940)	NC score	0.076783 (rank : 816)
Query Neighborhood Hits	458	Target Neighborhood Hits	214	Shared Neighborhood Hits	47
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

PROZ_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.214338 (rank : 342)
Query Neighborhood Hits	458	Target Neighborhood Hits	422	Shared Neighborhood Hits	179
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 942)	NC score	0.212766 (rank : 344)
Query Neighborhood Hits	458	Target Neighborhood Hits	410	Shared Neighborhood Hits	174
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PSG10_HUMAN
θ value	θ > 10 (rank : 943)	NC score	0.087834 (rank : 739)
Query Neighborhood Hits	458	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

PSG11_HUMAN
θ value	θ > 10 (rank : 944)	NC score	0.090301 (rank : 731)
Query Neighborhood Hits	458	Target Neighborhood Hits	223	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

PSG1_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.091793 (rank : 719)
Query Neighborhood Hits	458	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

PSG2_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.085776 (rank : 750)
Query Neighborhood Hits	458	Target Neighborhood Hits	229	Shared Neighborhood Hits	61
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

PSG3_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.098438 (rank : 676)
Query Neighborhood Hits	458	Target Neighborhood Hits	242	Shared Neighborhood Hits	66
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

PSG4_HUMAN
θ value	θ > 10 (rank : 948)	NC score	0.096931 (rank : 685)
Query Neighborhood Hits	458	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PSG5_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.076393 (rank : 820)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	61
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PSG6_HUMAN
θ value	θ > 10 (rank : 950)	NC score	0.088057 (rank : 738)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	59
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

PSG7_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.090806 (rank : 728)
Query Neighborhood Hits	458	Target Neighborhood Hits	239	Shared Neighborhood Hits	61
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

PSG8_HUMAN
θ value	θ > 10 (rank : 952)	NC score	0.094037 (rank : 705)
Query Neighborhood Hits	458	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

PSG9_HUMAN
θ value	θ > 10 (rank : 953)	NC score	0.079338 (rank : 799)
Query Neighborhood Hits	458	Target Neighborhood Hits	221	Shared Neighborhood Hits	58
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

PTK6_HUMAN
θ value	θ > 10 (rank : 954)	NC score	0.051487 (rank : 1059)
Query Neighborhood Hits	458	Target Neighborhood Hits	1020	Shared Neighborhood Hits	50
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 955)	NC score	0.052634 (rank : 1054)
Query Neighborhood Hits	458	Target Neighborhood Hits	1026	Shared Neighborhood Hits	50
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTK7_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.179241 (rank : 409)
Query Neighborhood Hits	458	Target Neighborhood Hits	1103	Shared Neighborhood Hits	118
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

PTN11_HUMAN
θ value	θ > 10 (rank : 957)	NC score	0.074626 (rank : 833)
Query Neighborhood Hits	458	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 958)	NC score	0.074629 (rank : 832)
Query Neighborhood Hits	458	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.081681 (rank : 786)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 960)	NC score	0.080934 (rank : 791)
Query Neighborhood Hits	458	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN13_HUMAN
θ value	θ > 10 (rank : 961)	NC score	0.056789 (rank : 990)
Query Neighborhood Hits	458	Target Neighborhood Hits	471	Shared Neighborhood Hits	21
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	θ > 10 (rank : 962)	NC score	0.057758 (rank : 983)
Query Neighborhood Hits	458	Target Neighborhood Hits	426	Shared Neighborhood Hits	21
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN14_HUMAN
θ value	θ > 10 (rank : 963)	NC score	0.065572 (rank : 899)
Query Neighborhood Hits	458	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	θ > 10 (rank : 964)	NC score	0.064820 (rank : 905)
Query Neighborhood Hits	458	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN18_HUMAN
θ value	θ > 10 (rank : 965)	NC score	0.081060 (rank : 790)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 966)	NC score	0.082718 (rank : 775)
Query Neighborhood Hits	458	Target Neighborhood Hits	134	Shared Neighborhood Hits	18
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 967)	NC score	0.082221 (rank : 781)
Query Neighborhood Hits	458	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 968)	NC score	0.082241 (rank : 780)
Query Neighborhood Hits	458	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN21_HUMAN
θ value	θ > 10 (rank : 969)	NC score	0.064292 (rank : 914)
Query Neighborhood Hits	458	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	θ > 10 (rank : 970)	NC score	0.064667 (rank : 908)
Query Neighborhood Hits	458	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN22_HUMAN
θ value	θ > 10 (rank : 971)	NC score	0.082342 (rank : 778)
Query Neighborhood Hits	458	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 972)	NC score	0.080569 (rank : 795)
Query Neighborhood Hits	458	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 973)	NC score	0.069126 (rank : 870)
Query Neighborhood Hits	458	Target Neighborhood Hits	646	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 974)	NC score	0.069988 (rank : 866)
Query Neighborhood Hits	458	Target Neighborhood Hits	726	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 975)	NC score	0.083689 (rank : 765)
Query Neighborhood Hits	458	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 976)	NC score	0.082988 (rank : 770)
Query Neighborhood Hits	458	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN3_HUMAN
θ value	θ > 10 (rank : 977)	NC score	0.062846 (rank : 929)
Query Neighborhood Hits	458	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
θ value	θ > 10 (rank : 978)	NC score	0.062179 (rank : 934)
Query Neighborhood Hits	458	Target Neighborhood Hits	303	Shared Neighborhood Hits	21
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN5_HUMAN
θ value	θ > 10 (rank : 979)	NC score	0.085194 (rank : 758)
Query Neighborhood Hits	458	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 980)	NC score	0.085291 (rank : 757)
Query Neighborhood Hits	458	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 981)	NC score	0.076789 (rank : 815)
Query Neighborhood Hits	458	Target Neighborhood Hits	234	Shared Neighborhood Hits	18
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 982)	NC score	0.076707 (rank : 818)
Query Neighborhood Hits	458	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 983)	NC score	0.085389 (rank : 755)
Query Neighborhood Hits	458	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 984)	NC score	0.085423 (rank : 753)
Query Neighborhood Hits	458	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 985)	NC score	0.084960 (rank : 759)
Query Neighborhood Hits	458	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 986)	NC score	0.085293 (rank : 756)
Query Neighborhood Hits	458	Target Neighborhood Hits	78	Shared Neighborhood Hits	16
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 987)	NC score	0.082935 (rank : 772)
Query Neighborhood Hits	458	Target Neighborhood Hits	103	Shared Neighborhood Hits	17
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 988)	NC score	0.082978 (rank : 771)
Query Neighborhood Hits	458	Target Neighborhood Hits	120	Shared Neighborhood Hits	18
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 989)	NC score	0.106615 (rank : 645)
Query Neighborhood Hits	458	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 990)	NC score	0.106310 (rank : 647)
Query Neighborhood Hits	458	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_HUMAN
θ value	θ > 10 (rank : 991)	NC score	0.106726 (rank : 641)
Query Neighborhood Hits	458	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 992)	NC score	0.106959 (rank : 639)
Query Neighborhood Hits	458	Target Neighborhood Hits	86	Shared Neighborhood Hits	16
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRG_HUMAN
θ value	θ > 10 (rank : 993)	NC score	0.106175 (rank : 648)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	55
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 994)	NC score	0.105435 (rank : 654)
Query Neighborhood Hits	458	Target Neighborhood Hits	260	Shared Neighborhood Hits	54
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 995)	NC score	0.170845 (rank : 429)
Query Neighborhood Hits	458	Target Neighborhood Hits	207	Shared Neighborhood Hits	97
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 996)	NC score	0.163241 (rank : 452)
Query Neighborhood Hits	458	Target Neighborhood Hits	188	Shared Neighborhood Hits	88
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRN_HUMAN
θ value	θ > 10 (rank : 997)	NC score	0.082430 (rank : 776)
Query Neighborhood Hits	458	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 998)	NC score	0.082255 (rank : 779)
Query Neighborhood Hits	458	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 999)	NC score	0.083324 (rank : 767)
Query Neighborhood Hits	458	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 1000)	NC score	0.083090 (rank : 769)
Query Neighborhood Hits	458	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PVRL1_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.056945 (rank : 989)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	39
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

PVRL1_MOUSE
θ value	θ > 10 (rank : 1002)	NC score	0.053492 (rank : 1045)
Query Neighborhood Hits	458	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

PVRL3_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.054720 (rank : 1019)
Query Neighborhood Hits	458	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

PVRL3_MOUSE
θ value	θ > 10 (rank : 1004)	NC score	0.060050 (rank : 961)
Query Neighborhood Hits	458	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

PVR_HUMAN
θ value	θ > 10 (rank : 1005)	NC score	0.052675 (rank : 1051)
Query Neighborhood Hits	458	Target Neighborhood Hits	195	Shared Neighborhood Hits	41
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

RAGE_HUMAN
θ value	θ > 10 (rank : 1006)	NC score	0.177933 (rank : 413)
Query Neighborhood Hits	458	Target Neighborhood Hits	269	Shared Neighborhood Hits	75
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RAGE_MOUSE
θ value	θ > 10 (rank : 1007)	NC score	0.168845 (rank : 437)
Query Neighborhood Hits	458	Target Neighborhood Hits	295	Shared Neighborhood Hits	73
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RECK_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.109120 (rank : 629)
Query Neighborhood Hits	458	Target Neighborhood Hits	189	Shared Neighborhood Hits	84
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 1009)	NC score	0.090900 (rank : 726)
Query Neighborhood Hits	458	Target Neighborhood Hits	158	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RET_HUMAN
θ value	θ > 10 (rank : 1010)	NC score	0.060806 (rank : 947)
Query Neighborhood Hits	458	Target Neighborhood Hits	873	Shared Neighborhood Hits	60
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 1011)	NC score	0.061464 (rank : 942)
Query Neighborhood Hits	458	Target Neighborhood Hits	884	Shared Neighborhood Hits	68
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIMB2_HUMAN
θ value	θ > 10 (rank : 1012)	NC score	0.100519 (rank : 669)
Query Neighborhood Hits	458	Target Neighborhood Hits	263	Shared Neighborhood Hits	56
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 1013)	NC score	0.096204 (rank : 690)
Query Neighborhood Hits	458	Target Neighborhood Hits	246	Shared Neighborhood Hits	49
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RON_HUMAN
θ value	θ > 10 (rank : 1014)	NC score	0.058375 (rank : 979)
Query Neighborhood Hits	458	Target Neighborhood Hits	842	Shared Neighborhood Hits	54
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 1015)	NC score	0.059520 (rank : 965)
Query Neighborhood Hits	458	Target Neighborhood Hits	836	Shared Neighborhood Hits	56
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 1016)	NC score	0.112375 (rank : 606)
Query Neighborhood Hits	458	Target Neighborhood Hits	1018	Shared Neighborhood Hits	120
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 1017)	NC score	0.110963 (rank : 615)
Query Neighborhood Hits	458	Target Neighborhood Hits	1025	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 1018)	NC score	0.116234 (rank : 589)
Query Neighborhood Hits	458	Target Neighborhood Hits	1014	Shared Neighborhood Hits	119
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 1019)	NC score	0.119715 (rank : 579)
Query Neighborhood Hits	458	Target Neighborhood Hits	1000	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

RSPO3_HUMAN
θ value	θ > 10 (rank : 1020)	NC score	0.059677 (rank : 963)
Query Neighborhood Hits	458	Target Neighborhood Hits	128	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 1021)	NC score	0.057765 (rank : 982)
Query Neighborhood Hits	458	Target Neighborhood Hits	120	Shared Neighborhood Hits	54
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 1022)	NC score	0.066126 (rank : 894)
Query Neighborhood Hits	458	Target Neighborhood Hits	110	Shared Neighborhood Hits	57
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 1023)	NC score	0.054611 (rank : 1021)
Query Neighborhood Hits	458	Target Neighborhood Hits	110	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RYK_HUMAN
θ value	θ > 10 (rank : 1024)	NC score	0.072173 (rank : 846)
Query Neighborhood Hits	458	Target Neighborhood Hits	701	Shared Neighborhood Hits	48
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 1025)	NC score	0.071008 (rank : 857)
Query Neighborhood Hits	458	Target Neighborhood Hits	715	Shared Neighborhood Hits	48
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SCUB3_HUMAN
θ value	θ > 10 (rank : 1026)	NC score	0.319060 (rank : 197)
Query Neighborhood Hits	458	Target Neighborhood Hits	428	Shared Neighborhood Hits	222
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 1027)	NC score	0.320877 (rank : 192)
Query Neighborhood Hits	458	Target Neighborhood Hits	442	Shared Neighborhood Hits	227
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SHBG_HUMAN
θ value	θ > 10 (rank : 1028)	NC score	0.060340 (rank : 958)
Query Neighborhood Hits	458	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 1029)	NC score	0.057633 (rank : 985)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SIG10_HUMAN
θ value	θ > 10 (rank : 1030)	NC score	0.136612 (rank : 525)
Query Neighborhood Hits	458	Target Neighborhood Hits	363	Shared Neighborhood Hits	72
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

SIG11_HUMAN
θ value	θ > 10 (rank : 1031)	NC score	0.136345 (rank : 526)
Query Neighborhood Hits	458	Target Neighborhood Hits	273	Shared Neighborhood Hits	74
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

SIG12_HUMAN
θ value	θ > 10 (rank : 1032)	NC score	0.071942 (rank : 849)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	69
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

SIGL5_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.083482 (rank : 766)
Query Neighborhood Hits	458	Target Neighborhood Hits	246	Shared Neighborhood Hits	60
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

SIGL5_MOUSE
θ value	θ > 10 (rank : 1034)	NC score	0.111422 (rank : 610)
Query Neighborhood Hits	458	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

SIGL6_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.067790 (rank : 881)
Query Neighborhood Hits	458	Target Neighborhood Hits	233	Shared Neighborhood Hits	64
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

SIGL8_HUMAN
θ value	θ > 10 (rank : 1036)	NC score	0.081852 (rank : 785)
Query Neighborhood Hits	458	Target Neighborhood Hits	252	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

SMDF_HUMAN
θ value	θ > 10 (rank : 1037)	NC score	0.086404 (rank : 745)
Query Neighborhood Hits	458	Target Neighborhood Hits	117	Shared Neighborhood Hits	57
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SN_HUMAN
θ value	θ > 10 (rank : 1038)	NC score	0.170940 (rank : 428)
Query Neighborhood Hits	458	Target Neighborhood Hits	434	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

SN_MOUSE
θ value	θ > 10 (rank : 1039)	NC score	0.177891 (rank : 414)
Query Neighborhood Hits	458	Target Neighborhood Hits	416	Shared Neighborhood Hits	79
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

SPEG_HUMAN
θ value	θ > 10 (rank : 1040)	NC score	0.122043 (rank : 569)
Query Neighborhood Hits	458	Target Neighborhood Hits	1762	Shared Neighborhood Hits	150
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
θ value	θ > 10 (rank : 1041)	NC score	0.123152 (rank : 565)
Query Neighborhood Hits	458	Target Neighborhood Hits	1959	Shared Neighborhood Hits	151
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPY1_MOUSE
θ value	θ > 10 (rank : 1042)	NC score	0.058402 (rank : 978)
Query Neighborhood Hits	458	Target Neighborhood Hits	57	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

SRC_HUMAN
θ value	θ > 10 (rank : 1043)	NC score	0.053657 (rank : 1041)
Query Neighborhood Hits	458	Target Neighborhood Hits	1058	Shared Neighborhood Hits	50
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRC_MOUSE
θ value	θ > 10 (rank : 1044)	NC score	0.054304 (rank : 1030)
Query Neighborhood Hits	458	Target Neighborhood Hits	1033	Shared Neighborhood Hits	51
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRMS_HUMAN
θ value	θ > 10 (rank : 1045)	NC score	0.056457 (rank : 992)
Query Neighborhood Hits	458	Target Neighborhood Hits	946	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 1046)	NC score	0.055436 (rank : 1008)
Query Neighborhood Hits	458	Target Neighborhood Hits	964	Shared Neighborhood Hits	50
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

STYK1_HUMAN
θ value	θ > 10 (rank : 1047)	NC score	0.061098 (rank : 944)
Query Neighborhood Hits	458	Target Neighborhood Hits	786	Shared Neighborhood Hits	52
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

STYK1_MOUSE
θ value	θ > 10 (rank : 1048)	NC score	0.063460 (rank : 919)
Query Neighborhood Hits	458	Target Neighborhood Hits	779	Shared Neighborhood Hits	51
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

SUSD1_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.261853 (rank : 265)
Query Neighborhood Hits	458	Target Neighborhood Hits	285	Shared Neighborhood Hits	165
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 1050)	NC score	0.150866 (rank : 495)
Query Neighborhood Hits	458	Target Neighborhood Hits	132	Shared Neighborhood Hits	100
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 1051)	NC score	0.176096 (rank : 418)
Query Neighborhood Hits	458	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 1052)	NC score	0.143260 (rank : 509)
Query Neighborhood Hits	458	Target Neighborhood Hits	131	Shared Neighborhood Hits	98
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTA_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.070489 (rank : 859)
Query Neighborhood Hits	458	Target Neighborhood Hits	239	Shared Neighborhood Hits	107
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 1054)	NC score	0.079605 (rank : 798)
Query Neighborhood Hits	458	Target Neighborhood Hits	244	Shared Neighborhood Hits	116
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEC_HUMAN
θ value	θ > 10 (rank : 1055)	NC score	0.054439 (rank : 1027)
Query Neighborhood Hits	458	Target Neighborhood Hits	1006	Shared Neighborhood Hits	50
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.054333 (rank : 1029)
Query Neighborhood Hits	458	Target Neighborhood Hits	1006	Shared Neighborhood Hits	50
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEFF2_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.200892 (rank : 359)
Query Neighborhood Hits	458	Target Neighborhood Hits	211	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 1058)	NC score	0.203842 (rank : 357)
Query Neighborhood Hits	458	Target Neighborhood Hits	214	Shared Neighborhood Hits	113
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEX14_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.050885 (rank : 1066)
Query Neighborhood Hits	458	Target Neighborhood Hits	1103	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TLL1_HUMAN
θ value	θ > 10 (rank : 1060)	NC score	0.066497 (rank : 889)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	98
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 1061)	NC score	0.069059 (rank : 872)
Query Neighborhood Hits	458	Target Neighborhood Hits	237	Shared Neighborhood Hits	100
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 1062)	NC score	0.068266 (rank : 879)
Query Neighborhood Hits	458	Target Neighborhood Hits	241	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 1063)	NC score	0.063336 (rank : 925)
Query Neighborhood Hits	458	Target Neighborhood Hits	240	Shared Neighborhood Hits	100
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TMIGD_HUMAN
θ value	θ > 10 (rank : 1064)	NC score	0.180791 (rank : 403)
Query Neighborhood Hits	458	Target Neighborhood Hits	240	Shared Neighborhood Hits	73
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TMIGD_MOUSE
θ value	θ > 10 (rank : 1065)	NC score	0.175420 (rank : 420)
Query Neighborhood Hits	458	Target Neighborhood Hits	234	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TNK1_HUMAN
θ value	θ > 10 (rank : 1066)	NC score	0.062900 (rank : 928)
Query Neighborhood Hits	458	Target Neighborhood Hits	815	Shared Neighborhood Hits	51
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 1067)	NC score	0.061923 (rank : 938)
Query Neighborhood Hits	458	Target Neighborhood Hits	806	Shared Neighborhood Hits	53
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TNR14_HUMAN
θ value	θ > 10 (rank : 1068)	NC score	0.065524 (rank : 900)
Query Neighborhood Hits	458	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR16_HUMAN
θ value	θ > 10 (rank : 1069)	NC score	0.086185 (rank : 749)
Query Neighborhood Hits	458	Target Neighborhood Hits	183	Shared Neighborhood Hits	90
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 1070)	NC score	0.073741 (rank : 837)
Query Neighborhood Hits	458	Target Neighborhood Hits	178	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR22_MOUSE
θ value	θ > 10 (rank : 1071)	NC score	0.050162 (rank : 1070)
Query Neighborhood Hits	458	Target Neighborhood Hits	97	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
θ value	θ > 10 (rank : 1072)	NC score	0.062604 (rank : 930)
Query Neighborhood Hits	458	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR25_HUMAN
θ value	θ > 10 (rank : 1073)	NC score	0.097470 (rank : 681)
Query Neighborhood Hits	458	Target Neighborhood Hits	172	Shared Neighborhood Hits	70
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR26_MOUSE
θ value	θ > 10 (rank : 1074)	NC score	0.055565 (rank : 1004)
Query Neighborhood Hits	458	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR4_HUMAN
θ value	θ > 10 (rank : 1075)	NC score	0.065950 (rank : 896)
Query Neighborhood Hits	458	Target Neighborhood Hits	152	Shared Neighborhood Hits	63
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR4_MOUSE
θ value	θ > 10 (rank : 1076)	NC score	0.068879 (rank : 874)
Query Neighborhood Hits	458	Target Neighborhood Hits	137	Shared Neighborhood Hits	62
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 1077)	NC score	0.056395 (rank : 993)
Query Neighborhood Hits	458	Target Neighborhood Hits	120	Shared Neighborhood Hits	51
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR9_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.066658 (rank : 887)
Query Neighborhood Hits	458	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR9_MOUSE
θ value	θ > 10 (rank : 1079)	NC score	0.054588 (rank : 1023)
Query Neighborhood Hits	458	Target Neighborhood Hits	137	Shared Neighborhood Hits	56
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TPA_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.060777 (rank : 948)
Query Neighborhood Hits	458	Target Neighborhood Hits	324	Shared Neighborhood Hits	118
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 1081)	NC score	0.061912 (rank : 939)
Query Neighborhood Hits	458	Target Neighborhood Hits	335	Shared Neighborhood Hits	122
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRBM_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.293248 (rank : 223)
Query Neighborhood Hits	458	Target Neighborhood Hits	339	Shared Neighborhood Hits	187
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 1083)	NC score	0.284053 (rank : 233)
Query Neighborhood Hits	458	Target Neighborhood Hits	361	Shared Neighborhood Hits	194
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRIO_HUMAN
θ value	θ > 10 (rank : 1084)	NC score	0.059845 (rank : 962)
Query Neighborhood Hits	458	Target Neighborhood Hits	1580	Shared Neighborhood Hits	124
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TSP2_HUMAN
θ value	θ > 10 (rank : 1085)	NC score	0.169492 (rank : 434)
Query Neighborhood Hits	458	Target Neighborhood Hits	359	Shared Neighborhood Hits	170
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 1086)	NC score	0.173831 (rank : 425)
Query Neighborhood Hits	458	Target Neighborhood Hits	352	Shared Neighborhood Hits	172
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.232065 (rank : 305)
Query Neighborhood Hits	458	Target Neighborhood Hits	250	Shared Neighborhood Hits	163
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 1088)	NC score	0.242686 (rank : 291)
Query Neighborhood Hits	458	Target Neighborhood Hits	247	Shared Neighborhood Hits	170
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TXK_HUMAN
θ value	θ > 10 (rank : 1089)	NC score	0.055224 (rank : 1009)
Query Neighborhood Hits	458	Target Neighborhood Hits	971	Shared Neighborhood Hits	50
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1090)	NC score	0.055863 (rank : 1000)
Query Neighborhood Hits	458	Target Neighborhood Hits	980	Shared Neighborhood Hits	50
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

UNC5A_HUMAN
θ value	θ > 10 (rank : 1091)	NC score	0.102724 (rank : 663)
Query Neighborhood Hits	458	Target Neighborhood Hits	198	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 1092)	NC score	0.091360 (rank : 723)
Query Neighborhood Hits	458	Target Neighborhood Hits	203	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 1093)	NC score	0.092996 (rank : 713)
Query Neighborhood Hits	458	Target Neighborhood Hits	225	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 1094)	NC score	0.092256 (rank : 717)
Query Neighborhood Hits	458	Target Neighborhood Hits	226	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 1095)	NC score	0.095307 (rank : 696)
Query Neighborhood Hits	458	Target Neighborhood Hits	226	Shared Neighborhood Hits	69
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 1096)	NC score	0.095311 (rank : 695)
Query Neighborhood Hits	458	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 1097)	NC score	0.110040 (rank : 618)
Query Neighborhood Hits	458	Target Neighborhood Hits	267	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 1098)	NC score	0.112943 (rank : 603)
Query Neighborhood Hits	458	Target Neighborhood Hits	268	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UROL1_HUMAN
θ value	θ > 10 (rank : 1099)	NC score	0.095585 (rank : 692)
Query Neighborhood Hits	458	Target Neighborhood Hits	213	Shared Neighborhood Hits	103
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 1100)	NC score	0.103264 (rank : 661)
Query Neighborhood Hits	458	Target Neighborhood Hits	235	Shared Neighborhood Hits	118
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

VASN_HUMAN
θ value	θ > 10 (rank : 1101)	NC score	0.076096 (rank : 821)
Query Neighborhood Hits	458	Target Neighborhood Hits	449	Shared Neighborhood Hits	116
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VASN_MOUSE
θ value	θ > 10 (rank : 1102)	NC score	0.071473 (rank : 851)
Query Neighborhood Hits	458	Target Neighborhood Hits	426	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VCAM1_HUMAN
θ value	θ > 10 (rank : 1103)	NC score	0.181693 (rank : 397)
Query Neighborhood Hits	458	Target Neighborhood Hits	352	Shared Neighborhood Hits	74
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

VCAM1_MOUSE
θ value	θ > 10 (rank : 1104)	NC score	0.184278 (rank : 390)
Query Neighborhood Hits	458	Target Neighborhood Hits	320	Shared Neighborhood Hits	72
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

VEGFC_HUMAN
θ value	θ > 10 (rank : 1105)	NC score	0.109418 (rank : 623)
Query Neighborhood Hits	458	Target Neighborhood Hits	128	Shared Neighborhood Hits	76
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VEGFC_MOUSE
θ value	θ > 10 (rank : 1106)	NC score	0.098824 (rank : 674)
Query Neighborhood Hits	458	Target Neighborhood Hits	119	Shared Neighborhood Hits	74
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VGFR1_HUMAN
θ value	θ > 10 (rank : 1107)	NC score	0.136726 (rank : 524)
Query Neighborhood Hits	458	Target Neighborhood Hits	1109	Shared Neighborhood Hits	116
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

VGFR1_MOUSE
θ value	θ > 10 (rank : 1108)	NC score	0.135640 (rank : 529)
Query Neighborhood Hits	458	Target Neighborhood Hits	1118	Shared Neighborhood Hits	117
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

VGFR2_HUMAN
θ value	θ > 10 (rank : 1109)	NC score	0.130257 (rank : 538)
Query Neighborhood Hits	458	Target Neighborhood Hits	1103	Shared Neighborhood Hits	117
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

VGFR2_MOUSE
θ value	θ > 10 (rank : 1110)	NC score	0.129132 (rank : 542)
Query Neighborhood Hits	458	Target Neighborhood Hits	1089	Shared Neighborhood Hits	116
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

VGFR3_HUMAN
θ value	θ > 10 (rank : 1111)	NC score	0.112777 (rank : 604)
Query Neighborhood Hits	458	Target Neighborhood Hits	1037	Shared Neighborhood Hits	115
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VGFR3_MOUSE
θ value	θ > 10 (rank : 1112)	NC score	0.110971 (rank : 614)
Query Neighborhood Hits	458	Target Neighborhood Hits	1056	Shared Neighborhood Hits	117
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VLDLR_MOUSE
θ value	θ > 10 (rank : 1113)	NC score	0.230331 (rank : 310)
Query Neighborhood Hits	458	Target Neighborhood Hits	360	Shared Neighborhood Hits	196
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VSIG2_HUMAN
θ value	θ > 10 (rank : 1114)	NC score	0.158176 (rank : 470)
Query Neighborhood Hits	458	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG2_MOUSE
θ value	θ > 10 (rank : 1115)	NC score	0.149215 (rank : 498)
Query Neighborhood Hits	458	Target Neighborhood Hits	316	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG4_HUMAN
θ value	θ > 10 (rank : 1116)	NC score	0.123353 (rank : 563)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

VWF_MOUSE
θ value	θ > 10 (rank : 1117)	NC score	0.155928 (rank : 482)
Query Neighborhood Hits	458	Target Neighborhood Hits	381	Shared Neighborhood Hits	153
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WFDC3_HUMAN
θ value	θ > 10 (rank : 1118)	NC score	0.065684 (rank : 897)
Query Neighborhood Hits	458	Target Neighborhood Hits	138	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

YES_HUMAN
θ value	θ > 10 (rank : 1119)	NC score	0.054876 (rank : 1018)
Query Neighborhood Hits	458	Target Neighborhood Hits	1059	Shared Neighborhood Hits	52
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 1120)	NC score	0.054689 (rank : 1020)
Query Neighborhood Hits	458	Target Neighborhood Hits	1052	Shared Neighborhood Hits	51
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ZAN_HUMAN
θ value	θ > 10 (rank : 1121)	NC score	0.176254 (rank : 417)
Query Neighborhood Hits	458	Target Neighborhood Hits	679	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAP70_HUMAN
θ value	θ > 10 (rank : 1122)	NC score	0.060443 (rank : 955)
Query Neighborhood Hits	458	Target Neighborhood Hits	893	Shared Neighborhood Hits	51
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 1123)	NC score	0.060432 (rank : 956)
Query Neighborhood Hits	458	Target Neighborhood Hits	905	Shared Neighborhood Hits	50
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZNFX1_MOUSE
θ value	θ > 10 (rank : 1124)	NC score	0.060558 (rank : 950)
Query Neighborhood Hits	458	Target Neighborhood Hits	407	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

ITB4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	458	Target Neighborhood Hits	458	Shared Neighborhood Hits	458
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB6_HUMAN
NC score	0.826157 (rank : 2)	θ value	2.1455e-110 (rank : 9)
Query Neighborhood Hits	458	Target Neighborhood Hits	318	Shared Neighborhood Hits	225
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
NC score	0.823552 (rank : 3)	θ value	1.25781e-110 (rank : 8)
Query Neighborhood Hits	458	Target Neighborhood Hits	341	Shared Neighborhood Hits	224
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB1_MOUSE
NC score	0.818767 (rank : 4)	θ value	6.65404e-120 (rank : 5)
Query Neighborhood Hits	458	Target Neighborhood Hits	283	Shared Neighborhood Hits	195
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB7_HUMAN
NC score	0.818457 (rank : 5)	θ value	8.4565e-99 (rank : 12)
Query Neighborhood Hits	458	Target Neighborhood Hits	290	Shared Neighborhood Hits	211
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
NC score	0.818387 (rank : 6)	θ value	2.80862e-102 (rank : 10)
Query Neighborhood Hits	458	Target Neighborhood Hits	277	Shared Neighborhood Hits	210
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB5_HUMAN
NC score	0.816903 (rank : 7)	θ value	7.37397e-111 (rank : 7)
Query Neighborhood Hits	458	Target Neighborhood Hits	310	Shared Neighborhood Hits	214
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB1_HUMAN
NC score	0.815970 (rank : 8)	θ value	1.69212e-123 (rank : 2)
Query Neighborhood Hits	458	Target Neighborhood Hits	298	Shared Neighborhood Hits	195
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB5_MOUSE
NC score	0.815496 (rank : 9)	θ value	2.5344e-111 (rank : 6)
Query Neighborhood Hits	458	Target Neighborhood Hits	329	Shared Neighborhood Hits	218
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB3_MOUSE
NC score	0.814092 (rank : 10)	θ value	1.43246e-122 (rank : 3)
Query Neighborhood Hits	458	Target Neighborhood Hits	319	Shared Neighborhood Hits	200
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB2_HUMAN
NC score	0.813717 (rank : 11)	θ value	1.03374e-96 (rank : 13)
Query Neighborhood Hits	458	Target Neighborhood Hits	282	Shared Neighborhood Hits	206
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
NC score	0.813474 (rank : 12)	θ value	3.4333e-100 (rank : 11)
Query Neighborhood Hits	458	Target Neighborhood Hits	326	Shared Neighborhood Hits	225
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
NC score	0.813260 (rank : 13)	θ value	7.86017e-121 (rank : 4)
Query Neighborhood Hits	458	Target Neighborhood Hits	325	Shared Neighborhood Hits	208
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB8_HUMAN
NC score	0.802012 (rank : 14)	θ value	3.81361e-83 (rank : 14)
Query Neighborhood Hits	458	Target Neighborhood Hits	280	Shared Neighborhood Hits	186
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

TENX_HUMAN
NC score	0.611129 (rank : 15)	θ value	9.56915e-18 (rank : 21)
Query Neighborhood Hits	458	Target Neighborhood Hits	789	Shared Neighborhood Hits	371
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TENA_HUMAN
NC score	0.600182 (rank : 16)	θ value	8.10077e-17 (rank : 23)
Query Neighborhood Hits	458	Target Neighborhood Hits	631	Shared Neighborhood Hits	362
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
NC score	0.590516 (rank : 17)	θ value	4.44505e-15 (rank : 26)
Query Neighborhood Hits	458	Target Neighborhood Hits	596	Shared Neighborhood Hits	350
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENR_HUMAN
NC score	0.587822 (rank : 18)	θ value	1.058e-16 (rank : 24)
Query Neighborhood Hits	458	Target Neighborhood Hits	526	Shared Neighborhood Hits	330
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
NC score	0.587335 (rank : 19)	θ value	6.20254e-17 (rank : 22)
Query Neighborhood Hits	458	Target Neighborhood Hits	531	Shared Neighborhood Hits	331
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

USH2A_MOUSE
NC score	0.586001 (rank : 20)	θ value	1.53129e-07 (rank : 100)
Query Neighborhood Hits	458	Target Neighborhood Hits	626	Shared Neighborhood Hits	338
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

USH2A_HUMAN
NC score	0.580530 (rank : 21)	θ value	6.87365e-08 (rank : 94)
Query Neighborhood Hits	458	Target Neighborhood Hits	600	Shared Neighborhood Hits	336
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

TENN_MOUSE
NC score	0.551562 (rank : 22)	θ value	1.74796e-11 (rank : 40)
Query Neighborhood Hits	458	Target Neighborhood Hits	484	Shared Neighborhood Hits	319
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

SREC2_MOUSE
NC score	0.548027 (rank : 23)	θ value	5.26297e-08 (rank : 89)
Query Neighborhood Hits	458	Target Neighborhood Hits	605	Shared Neighborhood Hits	260
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC2_HUMAN
NC score	0.545720 (rank : 24)	θ value	6.87365e-08 (rank : 92)
Query Neighborhood Hits	458	Target Neighborhood Hits	645	Shared Neighborhood Hits	261
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

WIF1_HUMAN
NC score	0.536133 (rank : 25)	θ value	0.00020696 (rank : 175)
Query Neighborhood Hits	458	Target Neighborhood Hits	392	Shared Neighborhood Hits	234
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
NC score	0.535171 (rank : 26)	θ value	0.000602161 (rank : 190)
Query Neighborhood Hits	458	Target Neighborhood Hits	393	Shared Neighborhood Hits	234
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KRA51_HUMAN
NC score	0.534330 (rank : 27)	θ value	0.0563607 (rank : 265)
Query Neighborhood Hits	458	Target Neighborhood Hits	288	Shared Neighborhood Hits	168
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

TENN_HUMAN
NC score	0.527783 (rank : 28)	θ value	7.34386e-10 (rank : 56)
Query Neighborhood Hits	458	Target Neighborhood Hits	453	Shared Neighborhood Hits	300
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

NAGPA_HUMAN
NC score	0.525735 (rank : 29)	θ value	1.99992e-07 (rank : 101)
Query Neighborhood Hits	458	Target Neighborhood Hits	282	Shared Neighborhood Hits	196
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SREC_HUMAN
NC score	0.524885 (rank : 30)	θ value	6.87365e-08 (rank : 93)
Query Neighborhood Hits	458	Target Neighborhood Hits	645	Shared Neighborhood Hits	266
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

KRA53_HUMAN
NC score	0.518927 (rank : 31)	θ value	0.279714 (rank : 312)
Query Neighborhood Hits	458	Target Neighborhood Hits	331	Shared Neighborhood Hits	187
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

DLK_HUMAN
NC score	0.517039 (rank : 32)	θ value	1.33837e-11 (rank : 36)
Query Neighborhood Hits	458	Target Neighborhood Hits	401	Shared Neighborhood Hits	247
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

KRA58_HUMAN
NC score	0.511732 (rank : 33)	θ value	0.0736092 (rank : 274)
Query Neighborhood Hits	458	Target Neighborhood Hits	324	Shared Neighborhood Hits	182
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

NAGPA_MOUSE
NC score	0.508684 (rank : 34)	θ value	9.92553e-07 (rank : 114)
Query Neighborhood Hits	458	Target Neighborhood Hits	308	Shared Neighborhood Hits	202
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

DLL4_MOUSE
NC score	0.508144 (rank : 35)	θ value	2.43908e-13 (rank : 29)
Query Neighborhood Hits	458	Target Neighborhood Hits	440	Shared Neighborhood Hits	248
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_HUMAN
NC score	0.507886 (rank : 36)	θ value	1.09485e-13 (rank : 28)
Query Neighborhood Hits	458	Target Neighborhood Hits	435	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLK_MOUSE
NC score	0.505998 (rank : 37)	θ value	1.33837e-11 (rank : 37)
Query Neighborhood Hits	458	Target Neighborhood Hits	374	Shared Neighborhood Hits	238
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

EGFL9_HUMAN
NC score	0.504389 (rank : 38)	θ value	1.53129e-07 (rank : 99)
Query Neighborhood Hits	458	Target Neighborhood Hits	365	Shared Neighborhood Hits	235
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

KRA59_HUMAN
NC score	0.503544 (rank : 39)	θ value	0.279714 (rank : 313)
Query Neighborhood Hits	458	Target Neighborhood Hits	310	Shared Neighborhood Hits	157
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

EGFL9_MOUSE
NC score	0.503452 (rank : 40)	θ value	8.11959e-09 (rank : 72)
Query Neighborhood Hits	458	Target Neighborhood Hits	379	Shared Neighborhood Hits	239
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

DLL3_HUMAN
NC score	0.497415 (rank : 41)	θ value	8.97725e-08 (rank : 95)
Query Neighborhood Hits	458	Target Neighborhood Hits	419	Shared Neighborhood Hits	236
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

JAG1_MOUSE
NC score	0.493692 (rank : 42)	θ value	3.18553e-13 (rank : 30)
Query Neighborhood Hits	458	Target Neighborhood Hits	518	Shared Neighborhood Hits	256
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
NC score	0.492801 (rank : 43)	θ value	5.43371e-13 (rank : 31)
Query Neighborhood Hits	458	Target Neighborhood Hits	514	Shared Neighborhood Hits	253
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

DLL1_HUMAN
NC score	0.492793 (rank : 44)	θ value	1.63604e-09 (rank : 61)
Query Neighborhood Hits	458	Target Neighborhood Hits	455	Shared Neighborhood Hits	253
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
NC score	0.490744 (rank : 45)	θ value	1.25267e-09 (rank : 59)
Query Neighborhood Hits	458	Target Neighborhood Hits	456	Shared Neighborhood Hits	250
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_MOUSE
NC score	0.489052 (rank : 46)	θ value	7.1131e-05 (rank : 157)
Query Neighborhood Hits	458	Target Neighborhood Hits	399	Shared Neighborhood Hits	240
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

JAG2_MOUSE
NC score	0.485230 (rank : 47)	θ value	1.74796e-11 (rank : 39)
Query Neighborhood Hits	458	Target Neighborhood Hits	504	Shared Neighborhood Hits	253
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

MEGF6_HUMAN
NC score	0.481770 (rank : 48)	θ value	2.0648e-12 (rank : 32)
Query Neighborhood Hits	458	Target Neighborhood Hits	671	Shared Neighborhood Hits	274
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

JAG2_HUMAN
NC score	0.481371 (rank : 49)	θ value	8.67504e-11 (rank : 46)
Query Neighborhood Hits	458	Target Neighborhood Hits	491	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

DNER_MOUSE
NC score	0.476722 (rank : 50)	θ value	3.41135e-07 (rank : 107)
Query Neighborhood Hits	458	Target Neighborhood Hits	413	Shared Neighborhood Hits	236
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DNER_HUMAN
NC score	0.474926 (rank : 51)	θ value	5.81887e-07 (rank : 110)
Query Neighborhood Hits	458	Target Neighborhood Hits	460	Shared Neighborhood Hits	239
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

KRA57_HUMAN
NC score	0.473905 (rank : 52)	θ value	0.47712 (rank : 328)
Query Neighborhood Hits	458	Target Neighborhood Hits	269	Shared Neighborhood Hits	161
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

STAB2_MOUSE
NC score	0.473771 (rank : 53)	θ value	6.21693e-09 (rank : 71)
Query Neighborhood Hits	458	Target Neighborhood Hits	528	Shared Neighborhood Hits	263
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB1_MOUSE
NC score	0.469211 (rank : 54)	θ value	1.38499e-08 (rank : 80)
Query Neighborhood Hits	458	Target Neighborhood Hits	566	Shared Neighborhood Hits	261
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB1_HUMAN
NC score	0.466192 (rank : 55)	θ value	8.11959e-09 (rank : 75)
Query Neighborhood Hits	458	Target Neighborhood Hits	546	Shared Neighborhood Hits	258
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_HUMAN
NC score	0.466185 (rank : 56)	θ value	2.13673e-09 (rank : 66)
Query Neighborhood Hits	458	Target Neighborhood Hits	534	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CRUM1_MOUSE
NC score	0.465225 (rank : 57)	θ value	4.0297e-08 (rank : 84)
Query Neighborhood Hits	458	Target Neighborhood Hits	444	Shared Neighborhood Hits	235
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM1_HUMAN
NC score	0.463590 (rank : 58)	θ value	1.17247e-07 (rank : 97)
Query Neighborhood Hits	458	Target Neighborhood Hits	457	Shared Neighborhood Hits	241
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
NC score	0.462396 (rank : 59)	θ value	2.44474e-05 (rank : 143)
Query Neighborhood Hits	458	Target Neighborhood Hits	453	Shared Neighborhood Hits	242
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

KRA55_HUMAN
NC score	0.459383 (rank : 60)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	458	Target Neighborhood Hits	257	Shared Neighborhood Hits	155
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
NC score	0.455449 (rank : 61)	θ value	2.36792 (rank : 375)
Query Neighborhood Hits	458	Target Neighborhood Hits	207	Shared Neighborhood Hits	136
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

FNDC3_MOUSE
NC score	0.451957 (rank : 62)	θ value	1.17247e-07 (rank : 98)
Query Neighborhood Hits	458	Target Neighborhood Hits	207	Shared Neighborhood Hits	147
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_HUMAN
NC score	0.450795 (rank : 63)	θ value	3.41135e-07 (rank : 108)
Query Neighborhood Hits	458	Target Neighborhood Hits	196	Shared Neighborhood Hits	150
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

MEGF9_HUMAN
NC score	0.450448 (rank : 64)	θ value	0.00175202 (rank : 204)
Query Neighborhood Hits	458	Target Neighborhood Hits	557	Shared Neighborhood Hits	238
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KRA54_HUMAN
NC score	0.445226 (rank : 65)	θ value	0.813845 (rank : 346)
Query Neighborhood Hits	458	Target Neighborhood Hits	270	Shared Neighborhood Hits	153
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

NOTC1_MOUSE
NC score	0.444380 (rank : 66)	θ value	1.47974e-10 (rank : 48)
Query Neighborhood Hits	458	Target Neighborhood Hits	916	Shared Neighborhood Hits	260
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LAMA5_MOUSE
NC score	0.439008 (rank : 67)	θ value	3.77169e-06 (rank : 125)
Query Neighborhood Hits	458	Target Neighborhood Hits	828	Shared Neighborhood Hits	270
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NOTC1_HUMAN
NC score	0.434772 (rank : 68)	θ value	4.30538e-10 (rank : 52)
Query Neighborhood Hits	458	Target Neighborhood Hits	906	Shared Neighborhood Hits	260
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KR510_HUMAN
NC score	0.434557 (rank : 69)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	458	Target Neighborhood Hits	217	Shared Neighborhood Hits	130
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

NOTC3_HUMAN
NC score	0.434367 (rank : 70)	θ value	1.63604e-09 (rank : 63)
Query Neighborhood Hits	458	Target Neighborhood Hits	1062	Shared Neighborhood Hits	266
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LAMA5_HUMAN
NC score	0.432976 (rank : 71)	θ value	6.43352e-06 (rank : 130)
Query Neighborhood Hits	458	Target Neighborhood Hits	976	Shared Neighborhood Hits	267
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

SDK1_MOUSE
NC score	0.432842 (rank : 72)	θ value	2.51237e-26 (rank : 15)
Query Neighborhood Hits	458	Target Neighborhood Hits	495	Shared Neighborhood Hits	164
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

NOTC3_MOUSE
NC score	0.432644 (rank : 73)	θ value	3.64472e-09 (rank : 69)
Query Neighborhood Hits	458	Target Neighborhood Hits	975	Shared Neighborhood Hits	267
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SDK2_MOUSE
NC score	0.432018 (rank : 74)	θ value	2.27762e-19 (rank : 20)
Query Neighborhood Hits	458	Target Neighborhood Hits	480	Shared Neighborhood Hits	163
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

MEGF9_MOUSE
NC score	0.430115 (rank : 75)	θ value	4.1701e-05 (rank : 152)
Query Neighborhood Hits	458	Target Neighborhood Hits	896	Shared Neighborhood Hits	231
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PGBM_MOUSE
NC score	0.430017 (rank : 76)	θ value	0.000786445 (rank : 193)
Query Neighborhood Hits	458	Target Neighborhood Hits	1073	Shared Neighborhood Hits	335
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_HUMAN
NC score	0.427877 (rank : 77)	θ value	0.00298849 (rank : 218)
Query Neighborhood Hits	458	Target Neighborhood Hits	1113	Shared Neighborhood Hits	338
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NOTC2_MOUSE
NC score	0.427519 (rank : 78)	θ value	1.38499e-08 (rank : 79)
Query Neighborhood Hits	458	Target Neighborhood Hits	1069	Shared Neighborhood Hits	261
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.427369 (rank : 79)	θ value	1.47974e-10 (rank : 49)
Query Neighborhood Hits	458	Target Neighborhood Hits	1113	Shared Neighborhood Hits	271
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SDK1_HUMAN
NC score	0.427209 (rank : 80)	θ value	3.51386e-20 (rank : 18)
Query Neighborhood Hits	458	Target Neighborhood Hits	511	Shared Neighborhood Hits	166
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
NC score	0.427108 (rank : 81)	θ value	1.38178e-16 (rank : 25)
Query Neighborhood Hits	458	Target Neighborhood Hits	495	Shared Neighborhood Hits	160
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

LAMB2_HUMAN
NC score	0.425278 (rank : 82)	θ value	1.69304e-06 (rank : 118)
Query Neighborhood Hits	458	Target Neighborhood Hits	692	Shared Neighborhood Hits	239
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
NC score	0.425179 (rank : 83)	θ value	2.44474e-05 (rank : 146)
Query Neighborhood Hits	458	Target Neighborhood Hits	722	Shared Neighborhood Hits	236
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

NOTC4_HUMAN
NC score	0.422995 (rank : 84)	θ value	7.34386e-10 (rank : 55)
Query Neighborhood Hits	458	Target Neighborhood Hits	905	Shared Neighborhood Hits	267
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
NC score	0.419496 (rank : 85)	θ value	1.63604e-09 (rank : 64)
Query Neighborhood Hits	458	Target Neighborhood Hits	872	Shared Neighborhood Hits	264
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

FINC_MOUSE
NC score	0.416168 (rank : 86)	θ value	2.21117e-06 (rank : 122)
Query Neighborhood Hits	458	Target Neighborhood Hits	309	Shared Neighborhood Hits	171
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FINC_HUMAN
NC score	0.415584 (rank : 87)	θ value	2.61198e-07 (rank : 104)
Query Neighborhood Hits	458	Target Neighborhood Hits	302	Shared Neighborhood Hits	173
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

LAMA1_HUMAN
NC score	0.412203 (rank : 88)	θ value	1.09739e-05 (rank : 133)
Query Neighborhood Hits	458	Target Neighborhood Hits	804	Shared Neighborhood Hits	258
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NEO1_MOUSE
NC score	0.412190 (rank : 89)	θ value	5.08577e-11 (rank : 44)
Query Neighborhood Hits	458	Target Neighborhood Hits	523	Shared Neighborhood Hits	165
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NEO1_HUMAN
NC score	0.411437 (rank : 90)	θ value	1.33837e-11 (rank : 38)
Query Neighborhood Hits	458	Target Neighborhood Hits	530	Shared Neighborhood Hits	164
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

LAMA1_MOUSE
NC score	0.408077 (rank : 91)	θ value	6.43352e-06 (rank : 129)
Query Neighborhood Hits	458	Target Neighborhood Hits	838	Shared Neighborhood Hits	262
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB1_MOUSE
NC score	0.407407 (rank : 92)	θ value	1.43324e-05 (rank : 136)
Query Neighborhood Hits	458	Target Neighborhood Hits	919	Shared Neighborhood Hits	227
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KRA52_HUMAN
NC score	0.407172 (rank : 93)	θ value	2.36792 (rank : 374)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	137
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LAMC3_MOUSE
NC score	0.406330 (rank : 94)	θ value	9.92553e-07 (rank : 113)
Query Neighborhood Hits	458	Target Neighborhood Hits	624	Shared Neighborhood Hits	236
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMB3_MOUSE
NC score	0.406174 (rank : 95)	θ value	6.87365e-08 (rank : 91)
Query Neighborhood Hits	458	Target Neighborhood Hits	444	Shared Neighborhood Hits	195
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

AGRIN_HUMAN
NC score	0.405590 (rank : 96)	θ value	0.0148317 (rank : 233)
Query Neighborhood Hits	458	Target Neighborhood Hits	582	Shared Neighborhood Hits	251
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NRCAM_HUMAN
NC score	0.403862 (rank : 97)	θ value	2.28291e-11 (rank : 42)
Query Neighborhood Hits	458	Target Neighborhood Hits	439	Shared Neighborhood Hits	150
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

FBN2_HUMAN
NC score	0.403630 (rank : 98)	θ value	1.29631e-06 (rank : 115)
Query Neighborhood Hits	458	Target Neighborhood Hits	560	Shared Neighborhood Hits	262
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
NC score	0.397899 (rank : 99)	θ value	0.00020696 (rank : 169)
Query Neighborhood Hits	458	Target Neighborhood Hits	543	Shared Neighborhood Hits	253
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LAMC3_HUMAN
NC score	0.397805 (rank : 100)	θ value	5.44631e-05 (rank : 155)
Query Neighborhood Hits	458	Target Neighborhood Hits	588	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF8_HUMAN
NC score	0.397577 (rank : 101)	θ value	0.0961366 (rank : 285)
Query Neighborhood Hits	458	Target Neighborhood Hits	528	Shared Neighborhood Hits	244
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

L1CAM_HUMAN
NC score	0.397517 (rank : 102)	θ value	7.84624e-12 (rank : 34)
Query Neighborhood Hits	458	Target Neighborhood Hits	457	Shared Neighborhood Hits	155
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

NRCAM_MOUSE
NC score	0.396876 (rank : 103)	θ value	2.69671e-12 (rank : 33)
Query Neighborhood Hits	458	Target Neighborhood Hits	432	Shared Neighborhood Hits	149
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

FBN1_MOUSE
NC score	0.396636 (rank : 104)	θ value	4.1701e-05 (rank : 151)
Query Neighborhood Hits	458	Target Neighborhood Hits	563	Shared Neighborhood Hits	261
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LAMB3_HUMAN
NC score	0.396534 (rank : 105)	θ value	1.69304e-06 (rank : 119)
Query Neighborhood Hits	458	Target Neighborhood Hits	461	Shared Neighborhood Hits	179
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LTBP2_MOUSE
NC score	0.396482 (rank : 106)	θ value	1.09739e-05 (rank : 134)
Query Neighborhood Hits	458	Target Neighborhood Hits	617	Shared Neighborhood Hits	256
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NELL2_HUMAN
NC score	0.396092 (rank : 107)	θ value	0.00390308 (rank : 220)
Query Neighborhood Hits	458	Target Neighborhood Hits	449	Shared Neighborhood Hits	246
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

DCC_HUMAN
NC score	0.395549 (rank : 108)	θ value	2.13673e-09 (rank : 65)
Query Neighborhood Hits	458	Target Neighborhood Hits	583	Shared Neighborhood Hits	163
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

LTBP4_MOUSE
NC score	0.394690 (rank : 109)	θ value	2.44474e-05 (rank : 147)
Query Neighborhood Hits	458	Target Neighborhood Hits	607	Shared Neighborhood Hits	253
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBN1_HUMAN
NC score	0.393897 (rank : 110)	θ value	2.44474e-05 (rank : 144)
Query Neighborhood Hits	458	Target Neighborhood Hits	557	Shared Neighborhood Hits	259
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.393772 (rank : 111)	θ value	1.87187e-05 (rank : 140)
Query Neighborhood Hits	458	Target Neighborhood Hits	549	Shared Neighborhood Hits	261
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LTBP2_HUMAN
NC score	0.393542 (rank : 112)	θ value	2.61198e-07 (rank : 106)
Query Neighborhood Hits	458	Target Neighborhood Hits	552	Shared Neighborhood Hits	262
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LAMC2_MOUSE
NC score	0.393502 (rank : 113)	θ value	0.00298849 (rank : 216)
Query Neighborhood Hits	458	Target Neighborhood Hits	614	Shared Neighborhood Hits	242
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

KR511_HUMAN
NC score	0.393207 (rank : 114)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	132
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

MYOM1_HUMAN
NC score	0.391991 (rank : 115)	θ value	2.98157e-11 (rank : 43)
Query Neighborhood Hits	458	Target Neighborhood Hits	405	Shared Neighborhood Hits	142
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NELL2_MOUSE
NC score	0.391867 (rank : 116)	θ value	0.0330416 (rank : 252)
Query Neighborhood Hits	458	Target Neighborhood Hits	436	Shared Neighborhood Hits	247
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

KR171_HUMAN
NC score	0.391835 (rank : 117)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	458	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

MEGF8_MOUSE
NC score	0.388953 (rank : 118)	θ value	0.125558 (rank : 295)
Query Neighborhood Hits	458	Target Neighborhood Hits	520	Shared Neighborhood Hits	242
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

L1CAM_MOUSE
NC score	0.388640 (rank : 119)	θ value	9.59137e-10 (rank : 58)
Query Neighborhood Hits	458	Target Neighborhood Hits	457	Shared Neighborhood Hits	157
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LAMB1_HUMAN
NC score	0.388198 (rank : 120)	θ value	2.44474e-05 (rank : 145)
Query Neighborhood Hits	458	Target Neighborhood Hits	1018	Shared Neighborhood Hits	234
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMC1_MOUSE
NC score	0.388166 (rank : 121)	θ value	0.000158464 (rank : 167)
Query Neighborhood Hits	458	Target Neighborhood Hits	856	Shared Neighborhood Hits	240
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NFASC_HUMAN
NC score	0.386431 (rank : 122)	θ value	5.26297e-08 (rank : 88)
Query Neighborhood Hits	458	Target Neighborhood Hits	497	Shared Neighborhood Hits	154
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

DCC_MOUSE
NC score	0.385578 (rank : 123)	θ value	2.79066e-09 (rank : 67)
Query Neighborhood Hits	458	Target Neighborhood Hits	896	Shared Neighborhood Hits	173
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DSCL1_HUMAN
NC score	0.385131 (rank : 124)	θ value	1.63604e-09 (rank : 62)
Query Neighborhood Hits	458	Target Neighborhood Hits	589	Shared Neighborhood Hits	162
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

NELL1_HUMAN
NC score	0.384697 (rank : 125)	θ value	1.06291 (rank : 354)
Query Neighborhood Hits	458	Target Neighborhood Hits	451	Shared Neighborhood Hits	241
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LAMA2_HUMAN
NC score	0.383680 (rank : 126)	θ value	5.44631e-05 (rank : 154)
Query Neighborhood Hits	458	Target Neighborhood Hits	1092	Shared Neighborhood Hits	255
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CHL1_HUMAN
NC score	0.382842 (rank : 127)	θ value	2.52405e-10 (rank : 51)
Query Neighborhood Hits	458	Target Neighborhood Hits	413	Shared Neighborhood Hits	140
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

DSCAM_HUMAN
NC score	0.379219 (rank : 128)	θ value	1.02475e-11 (rank : 35)
Query Neighborhood Hits	458	Target Neighborhood Hits	524	Shared Neighborhood Hits	156
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

PTPRD_HUMAN
NC score	0.378691 (rank : 129)	θ value	1.42661e-21 (rank : 16)
Query Neighborhood Hits	458	Target Neighborhood Hits	485	Shared Neighborhood Hits	167
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CNTN3_MOUSE
NC score	0.378666 (rank : 130)	θ value	7.34386e-10 (rank : 54)
Query Neighborhood Hits	458	Target Neighborhood Hits	447	Shared Neighborhood Hits	147
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

MYOM2_HUMAN
NC score	0.376557 (rank : 131)	θ value	3.64472e-09 (rank : 68)
Query Neighborhood Hits	458	Target Neighborhood Hits	341	Shared Neighborhood Hits	134
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

CNTN3_HUMAN
NC score	0.376322 (rank : 132)	θ value	9.59137e-10 (rank : 57)
Query Neighborhood Hits	458	Target Neighborhood Hits	455	Shared Neighborhood Hits	151
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

PTPRD_MOUSE
NC score	0.376170 (rank : 133)	θ value	5.42112e-21 (rank : 17)
Query Neighborhood Hits	458	Target Neighborhood Hits	491	Shared Neighborhood Hits	161
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

HHIP_HUMAN
NC score	0.375264 (rank : 134)	θ value	0.0961366 (rank : 281)
Query Neighborhood Hits	458	Target Neighborhood Hits	249	Shared Neighborhood Hits	181
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

CNTN2_HUMAN
NC score	0.374831 (rank : 135)	θ value	1.38499e-08 (rank : 78)
Query Neighborhood Hits	458	Target Neighborhood Hits	440	Shared Neighborhood Hits	151
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

LAMA3_MOUSE
NC score	0.374265 (rank : 136)	θ value	2.61198e-07 (rank : 105)
Query Neighborhood Hits	458	Target Neighborhood Hits	859	Shared Neighborhood Hits	250
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

CHL1_MOUSE
NC score	0.374211 (rank : 137)	θ value	2.28291e-11 (rank : 41)
Query Neighborhood Hits	458	Target Neighborhood Hits	402	Shared Neighborhood Hits	138
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CREL1_HUMAN
NC score	0.373268 (rank : 138)	θ value	0.0252991 (rank : 243)
Query Neighborhood Hits	458	Target Neighborhood Hits	441	Shared Neighborhood Hits	206
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CNTN2_MOUSE
NC score	0.372772 (rank : 139)	θ value	1.63604e-09 (rank : 60)
Query Neighborhood Hits	458	Target Neighborhood Hits	450	Shared Neighborhood Hits	151
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

HHIP_MOUSE
NC score	0.370638 (rank : 140)	θ value	0.0736092 (rank : 273)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	176
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LAMC1_HUMAN
NC score	0.370419 (rank : 141)	θ value	0.00020696 (rank : 171)
Query Neighborhood Hits	458	Target Neighborhood Hits	922	Shared Neighborhood Hits	237
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

CNTN5_HUMAN
NC score	0.370248 (rank : 142)	θ value	2.36244e-08 (rank : 82)
Query Neighborhood Hits	458	Target Neighborhood Hits	446	Shared Neighborhood Hits	149
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

LAMA2_MOUSE
NC score	0.368631 (rank : 143)	θ value	0.00020696 (rank : 170)
Query Neighborhood Hits	458	Target Neighborhood Hits	1198	Shared Neighborhood Hits	257
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

PTPRF_HUMAN
NC score	0.368224 (rank : 144)	θ value	2.20605e-14 (rank : 27)
Query Neighborhood Hits	458	Target Neighborhood Hits	489	Shared Neighborhood Hits	160
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRS_HUMAN
NC score	0.368200 (rank : 145)	θ value	2.27762e-19 (rank : 19)
Query Neighborhood Hits	458	Target Neighborhood Hits	472	Shared Neighborhood Hits	158
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

LTBP3_HUMAN
NC score	0.367666 (rank : 146)	θ value	0.000270298 (rank : 180)
Query Neighborhood Hits	458	Target Neighborhood Hits	502	Shared Neighborhood Hits	241
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CNTN5_MOUSE
NC score	0.367410 (rank : 147)	θ value	6.21693e-09 (rank : 70)
Query Neighborhood Hits	458	Target Neighborhood Hits	434	Shared Neighborhood Hits	140
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

MYOM1_MOUSE
NC score	0.366960 (rank : 148)	θ value	2.21117e-06 (rank : 123)
Query Neighborhood Hits	458	Target Neighborhood Hits	415	Shared Neighborhood Hits	152
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

NTNG2_MOUSE
NC score	0.366930 (rank : 149)	θ value	0.163984 (rank : 302)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	201
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMC2_HUMAN
NC score	0.366445 (rank : 150)	θ value	0.0148317 (rank : 235)
Query Neighborhood Hits	458	Target Neighborhood Hits	715	Shared Neighborhood Hits	234
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

CNTN1_MOUSE
NC score	0.365573 (rank : 151)	θ value	1.38499e-08 (rank : 77)
Query Neighborhood Hits	458	Target Neighborhood Hits	422	Shared Neighborhood Hits	138
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

LTB1L_MOUSE
NC score	0.364839 (rank : 152)	θ value	0.00102713 (rank : 197)
Query Neighborhood Hits	458	Target Neighborhood Hits	514	Shared Neighborhood Hits	239
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.364493 (rank : 153)	θ value	0.00102713 (rank : 198)
Query Neighborhood Hits	458	Target Neighborhood Hits	479	Shared Neighborhood Hits	231
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NFASC_MOUSE
NC score	0.364360 (rank : 154)	θ value	0.000270298 (rank : 181)
Query Neighborhood Hits	458	Target Neighborhood Hits	475	Shared Neighborhood Hits	146
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

CNTN1_HUMAN
NC score	0.364277 (rank : 155)	θ value	5.26297e-08 (rank : 87)
Query Neighborhood Hits	458	Target Neighborhood Hits	431	Shared Neighborhood Hits	139
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

LTBP3_MOUSE
NC score	0.363952 (rank : 156)	θ value	0.00020696 (rank : 172)
Query Neighborhood Hits	458	Target Neighborhood Hits	475	Shared Neighborhood Hits	244
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CNTN6_HUMAN
NC score	0.361918 (rank : 157)	θ value	1.87187e-05 (rank : 138)
Query Neighborhood Hits	458	Target Neighborhood Hits	422	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CNTN4_HUMAN
NC score	0.359950 (rank : 158)	θ value	8.67504e-11 (rank : 45)
Query Neighborhood Hits	458	Target Neighborhood Hits	449	Shared Neighborhood Hits	135
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

LTB1L_HUMAN
NC score	0.358786 (rank : 159)	θ value	0.0961366 (rank : 283)
Query Neighborhood Hits	458	Target Neighborhood Hits	553	Shared Neighborhood Hits	248
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CNTN4_MOUSE
NC score	0.358717 (rank : 160)	θ value	5.62301e-10 (rank : 53)
Query Neighborhood Hits	458	Target Neighborhood Hits	445	Shared Neighborhood Hits	135
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

NTNG2_HUMAN
NC score	0.358288 (rank : 161)	θ value	0.47712 (rank : 329)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	197
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LTB1S_HUMAN
NC score	0.358059 (rank : 162)	θ value	0.0961366 (rank : 284)
Query Neighborhood Hits	458	Target Neighborhood Hits	502	Shared Neighborhood Hits	241
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CNTN6_MOUSE
NC score	0.356780 (rank : 163)	θ value	1.69304e-06 (rank : 116)
Query Neighborhood Hits	458	Target Neighborhood Hits	429	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

CREL1_MOUSE
NC score	0.355256 (rank : 164)	θ value	0.0113563 (rank : 230)
Query Neighborhood Hits	458	Target Neighborhood Hits	524	Shared Neighborhood Hits	211
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CUBN_MOUSE
NC score	0.351798 (rank : 165)	θ value	0.00390308 (rank : 219)
Query Neighborhood Hits	458	Target Neighborhood Hits	477	Shared Neighborhood Hits	226
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

HMCN1_HUMAN
NC score	0.347921 (rank : 166)	θ value	1.38821 (rank : 358)
Query Neighborhood Hits	458	Target Neighborhood Hits	983	Shared Neighborhood Hits	283
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KR104_HUMAN
NC score	0.344610 (rank : 167)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	458	Target Neighborhood Hits	313	Shared Neighborhood Hits	168
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

NTNG1_MOUSE
NC score	0.341750 (rank : 168)	θ value	0.0148317 (rank : 236)
Query Neighborhood Hits	458	Target Neighborhood Hits	246	Shared Neighborhood Hits	179
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

CUBN_HUMAN
NC score	0.340448 (rank : 169)	θ value	0.000786445 (rank : 192)
Query Neighborhood Hits	458	Target Neighborhood Hits	482	Shared Neighborhood Hits	230
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

EGFL7_HUMAN
NC score	0.337556 (rank : 170)	θ value	5.27518 (rank : 411)
Query Neighborhood Hits	458	Target Neighborhood Hits	325	Shared Neighborhood Hits	198
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

NTNG1_HUMAN
NC score	0.336876 (rank : 171)	θ value	0.00298849 (rank : 217)
Query Neighborhood Hits	458	Target Neighborhood Hits	247	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ROBO3_HUMAN
NC score	0.336215 (rank : 172)	θ value	1.80886e-08 (rank : 81)
Query Neighborhood Hits	458	Target Neighborhood Hits	570	Shared Neighborhood Hits	146
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

ROBO2_HUMAN
NC score	0.334534 (rank : 173)	θ value	1.99992e-07 (rank : 102)
Query Neighborhood Hits	458	Target Neighborhood Hits	479	Shared Neighborhood Hits	143
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SLIT1_MOUSE
NC score	0.334379 (rank : 174)	θ value	0.00175202 (rank : 206)
Query Neighborhood Hits	458	Target Neighborhood Hits	715	Shared Neighborhood Hits	236
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ROBO2_MOUSE
NC score	0.333869 (rank : 175)	θ value	3.41135e-07 (rank : 109)
Query Neighborhood Hits	458	Target Neighborhood Hits	504	Shared Neighborhood Hits	146
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SLIT1_HUMAN
NC score	0.333032 (rank : 176)	θ value	0.00175202 (rank : 205)
Query Neighborhood Hits	458	Target Neighborhood Hits	700	Shared Neighborhood Hits	234
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

PUNC_HUMAN
NC score	0.332776 (rank : 177)	θ value	0.000121331 (rank : 164)
Query Neighborhood Hits	458	Target Neighborhood Hits	449	Shared Neighborhood Hits	137
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO3_MOUSE
NC score	0.330196 (rank : 178)	θ value	1.99992e-07 (rank : 103)
Query Neighborhood Hits	458	Target Neighborhood Hits	524	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

KR107_HUMAN
NC score	0.330116 (rank : 179)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	458	Target Neighborhood Hits	330	Shared Neighborhood Hits	175
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LRP1_HUMAN
NC score	0.329811 (rank : 180)	θ value	0.00102713 (rank : 196)
Query Neighborhood Hits	458	Target Neighborhood Hits	617	Shared Neighborhood Hits	263
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

GAS6_HUMAN
NC score	0.329260 (rank : 181)	θ value	0.0736092 (rank : 272)
Query Neighborhood Hits	458	Target Neighborhood Hits	348	Shared Neighborhood Hits	208
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
NC score	0.329135 (rank : 182)	θ value	5.44631e-05 (rank : 153)
Query Neighborhood Hits	458	Target Neighborhood Hits	343	Shared Neighborhood Hits	209
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ATRN_HUMAN
NC score	0.328476 (rank : 183)	θ value	0.00869519 (rank : 225)
Query Neighborhood Hits	458	Target Neighborhood Hits	525	Shared Neighborhood Hits	221
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

FBLN2_HUMAN
NC score	0.328370 (rank : 184)	θ value	0.00228821 (rank : 211)
Query Neighborhood Hits	458	Target Neighborhood Hits	392	Shared Neighborhood Hits	194
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

ATRN_MOUSE
NC score	0.327990 (rank : 185)	θ value	0.00228821 (rank : 208)
Query Neighborhood Hits	458	Target Neighborhood Hits	519	Shared Neighborhood Hits	215
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

PUNC_MOUSE
NC score	0.327611 (rank : 186)	θ value	0.000461057 (rank : 187)
Query Neighborhood Hits	458	Target Neighborhood Hits	501	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO1_MOUSE
NC score	0.325645 (rank : 187)	θ value	5.44631e-05 (rank : 156)
Query Neighborhood Hits	458	Target Neighborhood Hits	559	Shared Neighborhood Hits	149
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

EGFL7_MOUSE
NC score	0.325208 (rank : 188)	θ value	0.47712 (rank : 327)
Query Neighborhood Hits	458	Target Neighborhood Hits	287	Shared Neighborhood Hits	183
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

LRP1B_HUMAN
NC score	0.325086 (rank : 189)	θ value	0.00175202 (rank : 203)
Query Neighborhood Hits	458	Target Neighborhood Hits	602	Shared Neighborhood Hits	258
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SLIT2_HUMAN
NC score	0.322564 (rank : 190)	θ value	0.000786445 (rank : 195)
Query Neighborhood Hits	458	Target Neighborhood Hits	708	Shared Neighborhood Hits	237
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LRP1B_MOUSE
NC score	0.321310 (rank : 191)	θ value	0.00134147 (rank : 201)
Query Neighborhood Hits	458	Target Neighborhood Hits	606	Shared Neighborhood Hits	257
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SCUB3_MOUSE
NC score	0.320877 (rank : 192)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	458	Target Neighborhood Hits	442	Shared Neighborhood Hits	227
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ROBO1_HUMAN
NC score	0.320776 (rank : 193)	θ value	0.000602161 (rank : 189)
Query Neighborhood Hits	458	Target Neighborhood Hits	529	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

MT3_MOUSE
NC score	0.320618 (rank : 194)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	458	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

SORL_MOUSE
NC score	0.320244 (rank : 195)	θ value	0.00665767 (rank : 224)
Query Neighborhood Hits	458	Target Neighborhood Hits	439	Shared Neighborhood Hits	278
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

KR106_HUMAN
NC score	0.319132 (rank : 196)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	458	Target Neighborhood Hits	347	Shared Neighborhood Hits	173
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

SCUB3_HUMAN
NC score	0.319060 (rank : 197)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	458	Target Neighborhood Hits	428	Shared Neighborhood Hits	222
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ZAN_MOUSE
NC score	0.318293 (rank : 198)	θ value	0.0961366 (rank : 290)
Query Neighborhood Hits	458	Target Neighborhood Hits	808	Shared Neighborhood Hits	269
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SLIT2_MOUSE
NC score	0.317753 (rank : 199)	θ value	0.00175202 (rank : 207)
Query Neighborhood Hits	458	Target Neighborhood Hits	684	Shared Neighborhood Hits	234
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_MOUSE
NC score	0.317024 (rank : 200)	θ value	3.19293e-05 (rank : 149)
Query Neighborhood Hits	458	Target Neighborhood Hits	700	Shared Neighborhood Hits	239
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

FBLN2_MOUSE
NC score	0.317006 (rank : 201)	θ value	0.0148317 (rank : 234)
Query Neighborhood Hits	458	Target Neighborhood Hits	505	Shared Neighborhood Hits	207
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

PROS_HUMAN
NC score	0.316494 (rank : 202)	θ value	0.21417 (rank : 309)
Query Neighborhood Hits	458	Target Neighborhood Hits	340	Shared Neighborhood Hits	210
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

COCA1_MOUSE
NC score	0.315596 (rank : 203)	θ value	6.87365e-08 (rank : 90)
Query Neighborhood Hits	458	Target Neighborhood Hits	467	Shared Neighborhood Hits	146
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

PROS_MOUSE
NC score	0.315412 (rank : 204)	θ value	0.0431538 (rank : 261)
Query Neighborhood Hits	458	Target Neighborhood Hits	330	Shared Neighborhood Hits	206
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SORL_HUMAN
NC score	0.311419 (rank : 205)	θ value	0.0736092 (rank : 276)
Query Neighborhood Hits	458	Target Neighborhood Hits	440	Shared Neighborhood Hits	271
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SLIT3_HUMAN
NC score	0.311222 (rank : 206)	θ value	1.87187e-05 (rank : 141)
Query Neighborhood Hits	458	Target Neighborhood Hits	682	Shared Neighborhood Hits	232
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

C1QR1_HUMAN
NC score	0.308259 (rank : 207)	θ value	0.163984 (rank : 297)
Query Neighborhood Hits	458	Target Neighborhood Hits	493	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

COCA1_HUMAN
NC score	0.307226 (rank : 208)	θ value	1.69304e-06 (rank : 117)
Query Neighborhood Hits	458	Target Neighborhood Hits	458	Shared Neighborhood Hits	142
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

LAMA3_HUMAN
NC score	0.306951 (rank : 209)	θ value	0.0961366 (rank : 282)
Query Neighborhood Hits	458	Target Neighborhood Hits	760	Shared Neighborhood Hits	218
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

EDIL3_MOUSE
NC score	0.305745 (rank : 210)	θ value	0.0563607 (rank : 264)
Query Neighborhood Hits	458	Target Neighborhood Hits	317	Shared Neighborhood Hits	199
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CDON_HUMAN
NC score	0.305612 (rank : 211)	θ value	0.000786445 (rank : 191)
Query Neighborhood Hits	458	Target Neighborhood Hits	412	Shared Neighborhood Hits	125
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

FBLN1_HUMAN
NC score	0.305547 (rank : 212)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	458	Target Neighborhood Hits	324	Shared Neighborhood Hits	197
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

CDON_MOUSE
NC score	0.303790 (rank : 213)	θ value	0.00175202 (rank : 202)
Query Neighborhood Hits	458	Target Neighborhood Hits	410	Shared Neighborhood Hits	123
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

BOC_HUMAN
NC score	0.303616 (rank : 214)	θ value	0.00228821 (rank : 209)
Query Neighborhood Hits	458	Target Neighborhood Hits	543	Shared Neighborhood Hits	133
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

FBLN1_MOUSE
NC score	0.302291 (rank : 215)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	458	Target Neighborhood Hits	329	Shared Neighborhood Hits	195
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FRAS1_HUMAN
NC score	0.301339 (rank : 216)	θ value	0.00298849 (rank : 215)
Query Neighborhood Hits	458	Target Neighborhood Hits	759	Shared Neighborhood Hits	233
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

TSP4_MOUSE
NC score	0.301084 (rank : 217)	θ value	0.0736092 (rank : 277)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	189
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_HUMAN
NC score	0.300971 (rank : 218)	θ value	1.38821 (rank : 365)
Query Neighborhood Hits	458	Target Neighborhood Hits	284	Shared Neighborhood Hits	188
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
NC score	0.299021 (rank : 219)	θ value	0.0961366 (rank : 289)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	189
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

BOC_MOUSE
NC score	0.298100 (rank : 220)	θ value	0.00298849 (rank : 212)
Query Neighborhood Hits	458	Target Neighborhood Hits	433	Shared Neighborhood Hits	123
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

FRAS1_MOUSE
NC score	0.295876 (rank : 221)	θ value	0.00869519 (rank : 227)
Query Neighborhood Hits	458	Target Neighborhood Hits	747	Shared Neighborhood Hits	227
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

EGFL8_MOUSE
NC score	0.295335 (rank : 222)	θ value	0.0961366 (rank : 279)
Query Neighborhood Hits	458	Target Neighborhood Hits	266	Shared Neighborhood Hits	170
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

TRBM_HUMAN
NC score	0.293248 (rank : 223)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	458	Target Neighborhood Hits	339	Shared Neighborhood Hits	187
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NID2_HUMAN
NC score	0.293234 (rank : 224)	θ value	1.38821 (rank : 361)
Query Neighborhood Hits	458	Target Neighborhood Hits	456	Shared Neighborhood Hits	204
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LAMA4_MOUSE
NC score	0.290636 (rank : 225)	θ value	3.0926 (rank : 393)
Query Neighborhood Hits	458	Target Neighborhood Hits	584	Shared Neighborhood Hits	192
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

PCSK5_MOUSE
NC score	0.290198 (rank : 226)	θ value	0.279714 (rank : 317)
Query Neighborhood Hits	458	Target Neighborhood Hits	613	Shared Neighborhood Hits	236
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

MATN2_HUMAN
NC score	0.289123 (rank : 227)	θ value	4.03905 (rank : 402)
Query Neighborhood Hits	458	Target Neighborhood Hits	365	Shared Neighborhood Hits	191
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

FBLN4_HUMAN
NC score	0.288202 (rank : 228)	θ value	0.62314 (rank : 336)
Query Neighborhood Hits	458	Target Neighborhood Hits	278	Shared Neighborhood Hits	177
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

MATN2_MOUSE
NC score	0.287939 (rank : 229)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	458	Target Neighborhood Hits	356	Shared Neighborhood Hits	184
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

EGF_MOUSE
NC score	0.287646 (rank : 230)	θ value	0.365318 (rank : 318)
Query Neighborhood Hits	458	Target Neighborhood Hits	358	Shared Neighborhood Hits	210
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

TSP4_HUMAN
NC score	0.287496 (rank : 231)	θ value	8.99809 (rank : 457)
Query Neighborhood Hits	458	Target Neighborhood Hits	277	Shared Neighborhood Hits	186
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

MYPC3_HUMAN
NC score	0.285898 (rank : 232)	θ value	0.00035302 (rank : 184)
Query Neighborhood Hits	458	Target Neighborhood Hits	318	Shared Neighborhood Hits	125
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

TRBM_MOUSE
NC score	0.284053 (rank : 233)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	458	Target Neighborhood Hits	361	Shared Neighborhood Hits	194
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

EGFL8_HUMAN
NC score	0.283100 (rank : 234)	θ value	5.27518 (rank : 412)
Query Neighborhood Hits	458	Target Neighborhood Hits	270	Shared Neighborhood Hits	170
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

C1QR1_MOUSE
NC score	0.282766 (rank : 235)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	458	Target Neighborhood Hits	342	Shared Neighborhood Hits	193
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

EDIL3_HUMAN
NC score	0.282719 (rank : 236)	θ value	0.47712 (rank : 326)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	179
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FBLN5_HUMAN
NC score	0.282646 (rank : 237)	θ value	0.0330416 (rank : 250)
Query Neighborhood Hits	458	Target Neighborhood Hits	329	Shared Neighborhood Hits	193
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

MT3_HUMAN
NC score	0.282563 (rank : 238)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	458	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

COMP_MOUSE
NC score	0.282085 (rank : 239)	θ value	0.0252991 (rank : 242)
Query Neighborhood Hits	458	Target Neighborhood Hits	290	Shared Neighborhood Hits	197
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KR101_HUMAN
NC score	0.281889 (rank : 240)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	458	Target Neighborhood Hits	261	Shared Neighborhood Hits	144
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

MYPC3_MOUSE
NC score	0.281625 (rank : 241)	θ value	0.00020696 (rank : 173)
Query Neighborhood Hits	458	Target Neighborhood Hits	310	Shared Neighborhood Hits	125
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

FBLN5_MOUSE
NC score	0.280881 (rank : 242)	θ value	0.00869519 (rank : 226)
Query Neighborhood Hits	458	Target Neighborhood Hits	317	Shared Neighborhood Hits	191
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

ROBO4_MOUSE
NC score	0.280635 (rank : 243)	θ value	0.0736092 (rank : 275)
Query Neighborhood Hits	458	Target Neighborhood Hits	358	Shared Neighborhood Hits	98
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

ROBO4_HUMAN
NC score	0.279990 (rank : 244)	θ value	0.0563607 (rank : 267)
Query Neighborhood Hits	458	Target Neighborhood Hits	364	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

TIE1_MOUSE
NC score	0.279388 (rank : 245)	θ value	1.47974e-10 (rank : 50)
Query Neighborhood Hits	458	Target Neighborhood Hits	1266	Shared Neighborhood Hits	332
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

FBLN4_MOUSE
NC score	0.277891 (rank : 246)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	458	Target Neighborhood Hits	270	Shared Neighborhood Hits	172
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

NID2_MOUSE
NC score	0.277878 (rank : 247)	θ value	1.81305 (rank : 372)
Query Neighborhood Hits	458	Target Neighborhood Hits	338	Shared Neighborhood Hits	189
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NCAM2_MOUSE
NC score	0.277678 (rank : 248)	θ value	0.813845 (rank : 349)
Query Neighborhood Hits	458	Target Neighborhood Hits	472	Shared Neighborhood Hits	136
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

TIE1_HUMAN
NC score	0.276299 (rank : 249)	θ value	8.11959e-09 (rank : 76)
Query Neighborhood Hits	458	Target Neighborhood Hits	1241	Shared Neighborhood Hits	336
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

FBLN3_HUMAN
NC score	0.275375 (rank : 250)	θ value	5.27518 (rank : 414)
Query Neighborhood Hits	458	Target Neighborhood Hits	293	Shared Neighborhood Hits	184
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

NET2_MOUSE
NC score	0.273991 (rank : 251)	θ value	1.38821 (rank : 360)
Query Neighborhood Hits	458	Target Neighborhood Hits	193	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NID1_MOUSE
NC score	0.273674 (rank : 252)	θ value	0.0431538 (rank : 259)
Query Neighborhood Hits	458	Target Neighborhood Hits	335	Shared Neighborhood Hits	189
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LAMA4_HUMAN
NC score	0.272573 (rank : 253)	θ value	1.81305 (rank : 371)
Query Neighborhood Hits	458	Target Neighborhood Hits	708	Shared Neighborhood Hits	194
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MYPC2_MOUSE
NC score	0.272138 (rank : 254)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	458	Target Neighborhood Hits	297	Shared Neighborhood Hits	111
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

COEA1_MOUSE
NC score	0.272001 (rank : 255)	θ value	2.44474e-05 (rank : 142)
Query Neighborhood Hits	458	Target Neighborhood Hits	402	Shared Neighborhood Hits	110
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

NID1_HUMAN
NC score	0.271611 (rank : 256)	θ value	5.27518 (rank : 419)
Query Neighborhood Hits	458	Target Neighborhood Hits	329	Shared Neighborhood Hits	193
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NCAM2_HUMAN
NC score	0.270750 (rank : 257)	θ value	0.62314 (rank : 340)
Query Neighborhood Hits	458	Target Neighborhood Hits	441	Shared Neighborhood Hits	134
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

NET2_HUMAN
NC score	0.267715 (rank : 258)	θ value	0.813845 (rank : 350)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	150
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET4_HUMAN
NC score	0.267513 (rank : 259)	θ value	5.27518 (rank : 418)
Query Neighborhood Hits	458	Target Neighborhood Hits	191	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
NC score	0.267283 (rank : 260)	θ value	0.365318 (rank : 320)
Query Neighborhood Hits	458	Target Neighborhood Hits	180	Shared Neighborhood Hits	149
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

FBLN3_MOUSE
NC score	0.267101 (rank : 261)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	458	Target Neighborhood Hits	279	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

MYPC2_HUMAN
NC score	0.266878 (rank : 262)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	458	Target Neighborhood Hits	316	Shared Neighborhood Hits	120
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

COMP_HUMAN
NC score	0.266198 (rank : 263)	θ value	0.21417 (rank : 308)
Query Neighborhood Hits	458	Target Neighborhood Hits	258	Shared Neighborhood Hits	183
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

IL6RB_HUMAN
NC score	0.264867 (rank : 264)	θ value	0.125558 (rank : 294)
Query Neighborhood Hits	458	Target Neighborhood Hits	181	Shared Neighborhood Hits	117
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

SUSD1_HUMAN
NC score	0.261853 (rank : 265)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	458	Target Neighborhood Hits	285	Shared Neighborhood Hits	165
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

PTPRM_HUMAN
NC score	0.259898 (rank : 266)	θ value	2.44474e-05 (rank : 148)
Query Neighborhood Hits	458	Target Neighborhood Hits	244	Shared Neighborhood Hits	128
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

LRP2_HUMAN
NC score	0.259567 (rank : 267)	θ value	2.36792 (rank : 376)
Query Neighborhood Hits	458	Target Neighborhood Hits	573	Shared Neighborhood Hits	257
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

PTPRM_MOUSE
NC score	0.259511 (rank : 268)	θ value	1.43324e-05 (rank : 137)
Query Neighborhood Hits	458	Target Neighborhood Hits	238	Shared Neighborhood Hits	129
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

TIE2_HUMAN
NC score	0.256440 (rank : 269)	θ value	0.00390308 (rank : 221)
Query Neighborhood Hits	458	Target Neighborhood Hits	1192	Shared Neighborhood Hits	329
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

EGF_HUMAN
NC score	0.256175 (rank : 270)	θ value	3.0926 (rank : 386)
Query Neighborhood Hits	458	Target Neighborhood Hits	343	Shared Neighborhood Hits	199
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

MYPC1_HUMAN
NC score	0.255787 (rank : 271)	θ value	3.0926 (rank : 394)
Query Neighborhood Hits	458	Target Neighborhood Hits	303	Shared Neighborhood Hits	108
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

EMR1_HUMAN
NC score	0.254832 (rank : 272)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	458	Target Neighborhood Hits	382	Shared Neighborhood Hits	184
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

CSPG3_MOUSE
NC score	0.253392 (rank : 273)	θ value	0.0193708 (rank : 237)
Query Neighborhood Hits	458	Target Neighborhood Hits	657	Shared Neighborhood Hits	211
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

NPHN_HUMAN
NC score	0.253101 (rank : 274)	θ value	6.88961 (rank : 433)
Query Neighborhood Hits	458	Target Neighborhood Hits	362	Shared Neighborhood Hits	106
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

KR102_HUMAN
NC score	0.253006 (rank : 275)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	458	Target Neighborhood Hits	264	Shared Neighborhood Hits	138
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

CSPG3_HUMAN
NC score	0.252152 (rank : 276)	θ value	0.00228821 (rank : 210)
Query Neighborhood Hits	458	Target Neighborhood Hits	676	Shared Neighborhood Hits	208
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

RELN_MOUSE
NC score	0.251121 (rank : 277)	θ value	0.0252991 (rank : 247)
Query Neighborhood Hits	458	Target Neighborhood Hits	235	Shared Neighborhood Hits	158
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

TIE2_MOUSE
NC score	0.251107 (rank : 278)	θ value	0.0961366 (rank : 288)
Query Neighborhood Hits	458	Target Neighborhood Hits	1204	Shared Neighborhood Hits	328
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

NCA11_HUMAN
NC score	0.249557 (rank : 279)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	458	Target Neighborhood Hits	443	Shared Neighborhood Hits	122
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

RELN_HUMAN
NC score	0.249235 (rank : 280)	θ value	0.0252991 (rank : 246)
Query Neighborhood Hits	458	Target Neighborhood Hits	233	Shared Neighborhood Hits	157
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

COKA1_HUMAN
NC score	0.249166 (rank : 281)	θ value	2.88788e-06 (rank : 124)
Query Neighborhood Hits	458	Target Neighborhood Hits	403	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

COEA1_HUMAN
NC score	0.249046 (rank : 282)	θ value	8.40245e-06 (rank : 131)
Query Neighborhood Hits	458	Target Neighborhood Hits	427	Shared Neighborhood Hits	125
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

NCA11_MOUSE
NC score	0.247991 (rank : 283)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	458	Target Neighborhood Hits	661	Shared Neighborhood Hits	131
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PTPRT_MOUSE
NC score	0.246289 (rank : 284)	θ value	0.00035302 (rank : 186)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	120
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

CRIM1_HUMAN
NC score	0.246206 (rank : 285)	θ value	0.0252991 (rank : 244)
Query Neighborhood Hits	458	Target Neighborhood Hits	362	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

PTPRT_HUMAN
NC score	0.246009 (rank : 286)	θ value	0.00035302 (rank : 185)
Query Neighborhood Hits	458	Target Neighborhood Hits	217	Shared Neighborhood Hits	120
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRU_HUMAN
NC score	0.245559 (rank : 287)	θ value	1.69304e-06 (rank : 121)
Query Neighborhood Hits	458	Target Neighborhood Hits	237	Shared Neighborhood Hits	128
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

NPHN_MOUSE
NC score	0.244539 (rank : 288)	θ value	3.0926 (rank : 395)
Query Neighborhood Hits	458	Target Neighborhood Hits	370	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

LDLR_HUMAN
NC score	0.244096 (rank : 289)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	458	Target Neighborhood Hits	375	Shared Neighborhood Hits	205
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

NCA12_MOUSE
NC score	0.242812 (rank : 290)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	458	Target Neighborhood Hits	399	Shared Neighborhood Hits	109
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

TSP3_MOUSE
NC score	0.242686 (rank : 291)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	458	Target Neighborhood Hits	247	Shared Neighborhood Hits	170
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

CSPG2_MOUSE
NC score	0.242518 (rank : 292)	θ value	3.0926 (rank : 384)
Query Neighborhood Hits	458	Target Neighborhood Hits	711	Shared Neighborhood Hits	212
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

OBSL1_HUMAN
NC score	0.241261 (rank : 293)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	458	Target Neighborhood Hits	354	Shared Neighborhood Hits	79
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

NCA12_HUMAN
NC score	0.239604 (rank : 294)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	458	Target Neighborhood Hits	437	Shared Neighborhood Hits	117
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

VLDLR_HUMAN
NC score	0.239366 (rank : 295)	θ value	4.03905 (rank : 406)
Query Neighborhood Hits	458	Target Neighborhood Hits	383	Shared Neighborhood Hits	198
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

NET1_HUMAN
NC score	0.239293 (rank : 296)	θ value	0.279714 (rank : 315)
Query Neighborhood Hits	458	Target Neighborhood Hits	149	Shared Neighborhood Hits	120
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

EMR2_HUMAN
NC score	0.238351 (rank : 297)	θ value	0.813845 (rank : 345)
Query Neighborhood Hits	458	Target Neighborhood Hits	345	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

CSPG2_HUMAN
NC score	0.238294 (rank : 298)	θ value	6.88961 (rank : 425)
Query Neighborhood Hits	458	Target Neighborhood Hits	681	Shared Neighborhood Hits	212
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

NET1_MOUSE
NC score	0.234890 (rank : 299)	θ value	0.279714 (rank : 316)
Query Neighborhood Hits	458	Target Neighborhood Hits	151	Shared Neighborhood Hits	119
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

EMR1_MOUSE
NC score	0.234757 (rank : 300)	θ value	1.38821 (rank : 357)
Query Neighborhood Hits	458	Target Neighborhood Hits	349	Shared Neighborhood Hits	162
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

CT127_HUMAN
NC score	0.233741 (rank : 301)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	458	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CD97_HUMAN
NC score	0.233459 (rank : 302)	θ value	1.38821 (rank : 356)
Query Neighborhood Hits	458	Target Neighborhood Hits	353	Shared Neighborhood Hits	177
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

KR105_HUMAN
NC score	0.233328 (rank : 303)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	458	Target Neighborhood Hits	271	Shared Neighborhood Hits	147
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

GRN_HUMAN
NC score	0.232331 (rank : 304)	θ value	0.125558 (rank : 293)
Query Neighborhood Hits	458	Target Neighborhood Hits	268	Shared Neighborhood Hits	135
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

TSP3_HUMAN
NC score	0.232065 (rank : 305)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	458	Target Neighborhood Hits	250	Shared Neighborhood Hits	163
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

MATN3_HUMAN
NC score	0.231224 (rank : 306)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	458	Target Neighborhood Hits	268	Shared Neighborhood Hits	150
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

IL6RB_MOUSE
NC score	0.230605 (rank : 307)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	458	Target Neighborhood Hits	168	Shared Neighborhood Hits	117
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

MYBPH_MOUSE
NC score	0.230519 (rank : 308)	θ value	0.0330416 (rank : 251)
Query Neighborhood Hits	458	Target Neighborhood Hits	290	Shared Neighborhood Hits	108
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

PTPRK_MOUSE
NC score	0.230488 (rank : 309)	θ value	2.36244e-08 (rank : 83)
Query Neighborhood Hits	458	Target Neighborhood Hits	223	Shared Neighborhood Hits	120
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

VLDLR_MOUSE
NC score	0.230331 (rank : 310)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	458	Target Neighborhood Hits	360	Shared Neighborhood Hits	196
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

MAMC1_MOUSE
NC score	0.230118 (rank : 311)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	458	Target Neighborhood Hits	357	Shared Neighborhood Hits	83
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MDGA1_HUMAN
NC score	0.229844 (rank : 312)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	458	Target Neighborhood Hits	358	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MATN3_MOUSE
NC score	0.229825 (rank : 313)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	458	Target Neighborhood Hits	261	Shared Neighborhood Hits	154
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MAMC1_HUMAN
NC score	0.229389 (rank : 314)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	458	Target Neighborhood Hits	357	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

HCFC2_MOUSE
NC score	0.228679 (rank : 315)	θ value	0.00869519 (rank : 228)
Query Neighborhood Hits	458	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

GRN_MOUSE
NC score	0.228080 (rank : 316)	θ value	3.0926 (rank : 389)
Query Neighborhood Hits	458	Target Neighborhood Hits	248	Shared Neighborhood Hits	134
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

PTPRK_HUMAN
NC score	0.228055 (rank : 317)	θ value	4.0297e-08 (rank : 86)
Query Neighborhood Hits	458	Target Neighborhood Hits	228	Shared Neighborhood Hits	121
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

MYPN_HUMAN
NC score	0.227995 (rank : 318)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	458	Target Neighborhood Hits	418	Shared Neighborhood Hits	85
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYOTI_MOUSE
NC score	0.226878 (rank : 319)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	458	Target Neighborhood Hits	297	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

FGRL1_HUMAN
NC score	0.226080 (rank : 320)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	458	Target Neighborhood Hits	335	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

I12R2_HUMAN
NC score	0.225901 (rank : 321)	θ value	6.88961 (rank : 430)
Query Neighborhood Hits	458	Target Neighborhood Hits	163	Shared Neighborhood Hits	108
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

FGRL1_MOUSE
NC score	0.225113 (rank : 322)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	458	Target Neighborhood Hits	325	Shared Neighborhood Hits	80
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

MFGM_MOUSE
NC score	0.224621 (rank : 323)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	458	Target Neighborhood Hits	233	Shared Neighborhood Hits	154
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MYOTI_HUMAN
NC score	0.224353 (rank : 324)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

NRG2_MOUSE
NC score	0.224075 (rank : 325)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	458	Target Neighborhood Hits	392	Shared Neighborhood Hits	166
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

LRP8_MOUSE
NC score	0.223652 (rank : 326)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	458	Target Neighborhood Hits	385	Shared Neighborhood Hits	193
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MYPN_MOUSE
NC score	0.223363 (rank : 327)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	458	Target Neighborhood Hits	421	Shared Neighborhood Hits	84
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

LDLR_MOUSE
NC score	0.223090 (rank : 328)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	458	Target Neighborhood Hits	382	Shared Neighborhood Hits	199
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CO7A1_HUMAN
NC score	0.222159 (rank : 329)	θ value	0.0113563 (rank : 229)
Query Neighborhood Hits	458	Target Neighborhood Hits	807	Shared Neighborhood Hits	152
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MYBPH_HUMAN
NC score	0.220311 (rank : 330)	θ value	0.163984 (rank : 301)
Query Neighborhood Hits	458	Target Neighborhood Hits	256	Shared Neighborhood Hits	101
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

SSPO_MOUSE
NC score	0.220134 (rank : 331)	θ value	0.0961366 (rank : 287)
Query Neighborhood Hits	458	Target Neighborhood Hits	800	Shared Neighborhood Hits	245
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

KR109_HUMAN
NC score	0.219783 (rank : 332)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	458	Target Neighborhood Hits	226	Shared Neighborhood Hits	125
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

FATH_HUMAN
NC score	0.219199 (rank : 333)	θ value	4.03905 (rank : 401)
Query Neighborhood Hits	458	Target Neighborhood Hits	570	Shared Neighborhood Hits	225
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

KR10C_HUMAN
NC score	0.219190 (rank : 334)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	125
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

CELR3_HUMAN
NC score	0.218993 (rank : 335)	θ value	0.00134147 (rank : 200)
Query Neighborhood Hits	458	Target Neighborhood Hits	680	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR2_HUMAN
NC score	0.218317 (rank : 336)	θ value	0.0330416 (rank : 248)
Query Neighborhood Hits	458	Target Neighborhood Hits	657	Shared Neighborhood Hits	231
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

KR108_HUMAN
NC score	0.217866 (rank : 337)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	458	Target Neighborhood Hits	226	Shared Neighborhood Hits	126
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

MT4_MOUSE
NC score	0.217772 (rank : 338)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

CELR1_HUMAN
NC score	0.215803 (rank : 339)	θ value	0.125558 (rank : 291)
Query Neighborhood Hits	458	Target Neighborhood Hits	613	Shared Neighborhood Hits	220
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

TITIN_HUMAN
NC score	0.215087 (rank : 340)	θ value	8.67504e-11 (rank : 47)
Query Neighborhood Hits	458	Target Neighborhood Hits	2923	Shared Neighborhood Hits	211
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

LIFR_MOUSE
NC score	0.214679 (rank : 341)	θ value	1.38821 (rank : 359)
Query Neighborhood Hits	458	Target Neighborhood Hits	127	Shared Neighborhood Hits	87
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

PROZ_HUMAN
NC score	0.214338 (rank : 342)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	458	Target Neighborhood Hits	422	Shared Neighborhood Hits	179
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CELR3_MOUSE
NC score	0.213264 (rank : 343)	θ value	0.0563607 (rank : 263)
Query Neighborhood Hits	458	Target Neighborhood Hits	687	Shared Neighborhood Hits	232
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

PROZ_MOUSE
NC score	0.212766 (rank : 344)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	458	Target Neighborhood Hits	410	Shared Neighborhood Hits	174
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

I12R2_MOUSE
NC score	0.212754 (rank : 345)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	458	Target Neighborhood Hits	143	Shared Neighborhood Hits	103
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

NRG2_HUMAN
NC score	0.212674 (rank : 346)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	458	Target Neighborhood Hits	419	Shared Neighborhood Hits	150
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

LIFR_HUMAN
NC score	0.212213 (rank : 347)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	458	Target Neighborhood Hits	130	Shared Neighborhood Hits	86
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

CELR1_MOUSE
NC score	0.211522 (rank : 348)	θ value	0.813845 (rank : 344)
Query Neighborhood Hits	458	Target Neighborhood Hits	617	Shared Neighborhood Hits	232
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CFC1_HUMAN
NC score	0.210906 (rank : 349)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	458	Target Neighborhood Hits	148	Shared Neighborhood Hits	123
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

PTPRB_HUMAN
NC score	0.209883 (rank : 350)	θ value	0.0330416 (rank : 253)
Query Neighborhood Hits	458	Target Neighborhood Hits	242	Shared Neighborhood Hits	101
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

ELTD1_MOUSE
NC score	0.208684 (rank : 351)	θ value	0.163984 (rank : 299)
Query Neighborhood Hits	458	Target Neighborhood Hits	288	Shared Neighborhood Hits	148
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

TSP1_MOUSE
NC score	0.208494 (rank : 352)	θ value	0.47712 (rank : 331)
Query Neighborhood Hits	458	Target Neighborhood Hits	396	Shared Neighborhood Hits	184
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

MATN4_HUMAN
NC score	0.208251 (rank : 353)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	458	Target Neighborhood Hits	287	Shared Neighborhood Hits	165
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

TSP1_HUMAN
NC score	0.207630 (rank : 354)	θ value	0.813845 (rank : 352)
Query Neighborhood Hits	458	Target Neighborhood Hits	389	Shared Neighborhood Hits	182
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

KR10B_HUMAN
NC score	0.206022 (rank : 355)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	458	Target Neighborhood Hits	269	Shared Neighborhood Hits	137
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LRP4_MOUSE
NC score	0.205459 (rank : 356)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	458	Target Neighborhood Hits	351	Shared Neighborhood Hits	188
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

TEFF2_MOUSE
NC score	0.203842 (rank : 357)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	458	Target Neighborhood Hits	214	Shared Neighborhood Hits	113
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

LRP4_HUMAN
NC score	0.203079 (rank : 358)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	458	Target Neighborhood Hits	355	Shared Neighborhood Hits	189
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

TEFF2_HUMAN
NC score	0.200892 (rank : 359)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	458	Target Neighborhood Hits	211	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

KRA47_HUMAN
NC score	0.200680 (rank : 360)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	458	Target Neighborhood Hits	204	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

CELR2_MOUSE
NC score	0.200359 (rank : 361)	θ value	0.125558 (rank : 292)
Query Neighborhood Hits	458	Target Neighborhood Hits	584	Shared Neighborhood Hits	219
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

LRP8_HUMAN
NC score	0.199697 (rank : 362)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	458	Target Neighborhood Hits	346	Shared Neighborhood Hits	179
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CD248_HUMAN
NC score	0.199584 (rank : 363)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	458	Target Neighborhood Hits	679	Shared Neighborhood Hits	178
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

KRA93_HUMAN
NC score	0.199382 (rank : 364)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	458	Target Neighborhood Hits	203	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

CSF3R_HUMAN
NC score	0.197172 (rank : 365)	θ value	0.163984 (rank : 298)
Query Neighborhood Hits	458	Target Neighborhood Hits	140	Shared Neighborhood Hits	92
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

KRA13_HUMAN
NC score	0.196797 (rank : 366)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	458	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

MATN4_MOUSE
NC score	0.196647 (rank : 367)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	458	Target Neighborhood Hits	277	Shared Neighborhood Hits	161
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MALT1_HUMAN
NC score	0.195998 (rank : 368)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

KRA44_HUMAN
NC score	0.195313 (rank : 369)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	458	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

MT2_MOUSE
NC score	0.194947 (rank : 370)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	458	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT4_HUMAN
NC score	0.194563 (rank : 371)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

KRA45_HUMAN
NC score	0.194408 (rank : 372)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

CD248_MOUSE
NC score	0.194249 (rank : 373)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	458	Target Neighborhood Hits	578	Shared Neighborhood Hits	166
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

KALM_HUMAN
NC score	0.192840 (rank : 374)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	458	Target Neighborhood Hits	114	Shared Neighborhood Hits	82
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

KRA11_HUMAN
NC score	0.192371 (rank : 375)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	458	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

LSAMP_MOUSE
NC score	0.191986 (rank : 376)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	458	Target Neighborhood Hits	344	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

KRA98_HUMAN
NC score	0.191740 (rank : 377)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	458	Target Neighborhood Hits	185	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

LYAM2_MOUSE
NC score	0.191328 (rank : 378)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	458	Target Neighborhood Hits	420	Shared Neighborhood Hits	195
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NEGR1_HUMAN
NC score	0.191259 (rank : 379)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	458	Target Neighborhood Hits	346	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

LSAMP_HUMAN
NC score	0.191090 (rank : 380)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	458	Target Neighborhood Hits	347	Shared Neighborhood Hits	75
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

KRA94_HUMAN
NC score	0.190849 (rank : 381)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	458	Target Neighborhood Hits	204	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

NEGR1_MOUSE
NC score	0.189965 (rank : 382)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	458	Target Neighborhood Hits	349	Shared Neighborhood Hits	74
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

PTPRV_MOUSE
NC score	0.188883 (rank : 383)	θ value	0.000786445 (rank : 194)
Query Neighborhood Hits	458	Target Neighborhood Hits	179	Shared Neighborhood Hits	76
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

OPCM_HUMAN
NC score	0.188077 (rank : 384)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	458	Target Neighborhood Hits	332	Shared Neighborhood Hits	77
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

CD97_MOUSE
NC score	0.187127 (rank : 385)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	458	Target Neighborhood Hits	295	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

FSTL4_MOUSE
NC score	0.186119 (rank : 386)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	458	Target Neighborhood Hits	333	Shared Neighborhood Hits	85
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

KAZD1_MOUSE
NC score	0.185175 (rank : 387)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	458	Target Neighborhood Hits	281	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KRA92_HUMAN
NC score	0.184805 (rank : 388)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	458	Target Neighborhood Hits	198	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KAZD1_HUMAN
NC score	0.184548 (rank : 389)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	458	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

VCAM1_MOUSE
NC score	0.184278 (rank : 390)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	458	Target Neighborhood Hits	320	Shared Neighborhood Hits	72
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

LCE1B_HUMAN
NC score	0.183973 (rank : 391)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	458	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

EPHB6_HUMAN
NC score	0.182830 (rank : 392)	θ value	0.000270298 (rank : 177)
Query Neighborhood Hits	458	Target Neighborhood Hits	912	Shared Neighborhood Hits	180
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

NTRI_MOUSE
NC score	0.182687 (rank : 393)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	458	Target Neighborhood Hits	342	Shared Neighborhood Hits	76
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

LCE1C_HUMAN
NC score	0.182656 (rank : 394)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	458	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

FSTL5_HUMAN
NC score	0.182385 (rank : 395)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	458	Target Neighborhood Hits	347	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

MT1B_HUMAN
NC score	0.182282 (rank : 396)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	458	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

VCAM1_HUMAN
NC score	0.181693 (rank : 397)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	458	Target Neighborhood Hits	352	Shared Neighborhood Hits	74
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

NPTN_HUMAN
NC score	0.181675 (rank : 398)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	458	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NRG1_HUMAN
NC score	0.181576 (rank : 399)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	458	Target Neighborhood Hits	285	Shared Neighborhood Hits	133
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

MAG_HUMAN
NC score	0.181544 (rank : 400)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	458	Target Neighborhood Hits	278	Shared Neighborhood Hits	76
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
NC score	0.181458 (rank : 401)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	458	Target Neighborhood Hits	271	Shared Neighborhood Hits	76
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

ICAM5_MOUSE
NC score	0.180908 (rank : 402)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	458	Target Neighborhood Hits	308	Shared Neighborhood Hits	73
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

TMIGD_HUMAN
NC score	0.180791 (rank : 403)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	458	Target Neighborhood Hits	240	Shared Neighborhood Hits	73
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

KR414_HUMAN
NC score	0.180779 (rank : 404)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	458	Target Neighborhood Hits	199	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

NTRI_HUMAN
NC score	0.180659 (rank : 405)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	458	Target Neighborhood Hits	344	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

FSTL4_HUMAN
NC score	0.179773 (rank : 406)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	458	Target Neighborhood Hits	344	Shared Neighborhood Hits	83
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

CFC1_MOUSE
NC score	0.179515 (rank : 407)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	458	Target Neighborhood Hits	125	Shared Neighborhood Hits	105
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

KIRR2_HUMAN
NC score	0.179242 (rank : 408)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	458	Target Neighborhood Hits	321	Shared Neighborhood Hits	70
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

PTK7_HUMAN
NC score	0.179241 (rank : 409)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	458	Target Neighborhood Hits	1103	Shared Neighborhood Hits	118
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

FSTL5_MOUSE
NC score	0.178459 (rank : 410)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	458	Target Neighborhood Hits	355	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

VWF_HUMAN
NC score	0.178284 (rank : 411)	θ value	0.813845 (rank : 353)
Query Neighborhood Hits	458	Target Neighborhood Hits	396	Shared Neighborhood Hits	167
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KIRR2_MOUSE
NC score	0.177979 (rank : 412)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	458	Target Neighborhood Hits	326	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

RAGE_HUMAN
NC score	0.177933 (rank : 413)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	458	Target Neighborhood Hits	269	Shared Neighborhood Hits	75
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

SN_MOUSE
NC score	0.177891 (rank : 414)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	458	Target Neighborhood Hits	416	Shared Neighborhood Hits	79
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

CI094_HUMAN
NC score	0.177491 (rank : 415)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	458	Target Neighborhood Hits	310	Shared Neighborhood Hits	81
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

MUC18_HUMAN
NC score	0.176699 (rank : 416)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	458	Target Neighborhood Hits	275	Shared Neighborhood Hits	71
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

ZAN_HUMAN
NC score	0.176254 (rank : 417)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	458	Target Neighborhood Hits	679	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

TDGF1_MOUSE
NC score	0.176096 (rank : 418)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	458	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

LU_HUMAN
NC score	0.175808 (rank : 419)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	458	Target Neighborhood Hits	283	Shared Neighborhood Hits	75
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

TMIGD_MOUSE
NC score	0.175420 (rank : 420)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	458	Target Neighborhood Hits	234	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

ICAM5_HUMAN
NC score	0.175399 (rank : 421)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	458	Target Neighborhood Hits	276	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

MUC5B_HUMAN
NC score	0.174206 (rank : 422)	θ value	4.03905 (rank : 403)
Query Neighborhood Hits	458	Target Neighborhood Hits	1020	Shared Neighborhood Hits	222
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

EPHB6_MOUSE
NC score	0.173904 (rank : 423)	θ value	0.00298849 (rank : 214)
Query Neighborhood Hits	458	Target Neighborhood Hits	906	Shared Neighborhood Hits	161
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

KRA99_HUMAN
NC score	0.173838 (rank : 424)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	458	Target Neighborhood Hits	173	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

TSP2_MOUSE
NC score	0.173831 (rank : 425)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	458	Target Neighborhood Hits	352	Shared Neighborhood Hits	172
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

JAM3_HUMAN
NC score	0.171444 (rank : 426)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	458	Target Neighborhood Hits	271	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

HABP2_HUMAN
NC score	0.171000 (rank : 427)	θ value	0.62314 (rank : 337)
Query Neighborhood Hits	458	Target Neighborhood Hits	431	Shared Neighborhood Hits	189
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

SN_HUMAN
NC score	0.170940 (rank : 428)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	458	Target Neighborhood Hits	434	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

PTPRJ_HUMAN
NC score	0.170845 (rank : 429)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	458	Target Neighborhood Hits	207	Shared Neighborhood Hits	97
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

LYAM2_HUMAN
NC score	0.170099 (rank : 430)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	458	Target Neighborhood Hits	394	Shared Neighborhood Hits	183
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

HABP2_MOUSE
NC score	0.169725 (rank : 431)	θ value	0.62314 (rank : 338)
Query Neighborhood Hits	458	Target Neighborhood Hits	445	Shared Neighborhood Hits	192
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

MT1A_HUMAN
NC score	0.169672 (rank : 432)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	458	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

KR412_HUMAN
NC score	0.169514 (rank : 433)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	458	Target Neighborhood Hits	178	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

TSP2_HUMAN
NC score	0.169492 (rank : 434)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	458	Target Neighborhood Hits	359	Shared Neighborhood Hits	170
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

JAM3_MOUSE
NC score	0.168967 (rank : 435)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	458	Target Neighborhood Hits	286	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

NPTN_MOUSE
NC score	0.168920 (rank : 436)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	458	Target Neighborhood Hits	216	Shared Neighborhood Hits	68
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

RAGE_MOUSE
NC score	0.168845 (rank : 437)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	458	Target Neighborhood Hits	295	Shared Neighborhood Hits	73
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

BASI_HUMAN
NC score	0.168339 (rank : 438)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	458	Target Neighborhood Hits	211	Shared Neighborhood Hits	66
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

EPHA7_HUMAN
NC score	0.167878 (rank : 439)	θ value	0.000121331 (rank : 161)
Query Neighborhood Hits	458	Target Neighborhood Hits	1053	Shared Neighborhood Hits	214
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHB4_HUMAN
NC score	0.167792 (rank : 440)	θ value	4.0297e-08 (rank : 85)
Query Neighborhood Hits	458	Target Neighborhood Hits	1056	Shared Neighborhood Hits	231
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

JAM1_HUMAN
NC score	0.167633 (rank : 441)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	458	Target Neighborhood Hits	294	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

CD22_MOUSE
NC score	0.166876 (rank : 442)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	458	Target Neighborhood Hits	331	Shared Neighborhood Hits	67
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

IBP7_MOUSE
NC score	0.166129 (rank : 443)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	458	Target Neighborhood Hits	230	Shared Neighborhood Hits	83
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

MUC18_MOUSE
NC score	0.166113 (rank : 444)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

IBP7_HUMAN
NC score	0.165472 (rank : 445)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	458	Target Neighborhood Hits	220	Shared Neighborhood Hits	76
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

MUSK_HUMAN
NC score	0.165457 (rank : 446)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	458	Target Neighborhood Hits	1074	Shared Neighborhood Hits	118
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

LRIG2_HUMAN
NC score	0.165363 (rank : 447)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	458	Target Neighborhood Hits	595	Shared Neighborhood Hits	89
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

MUSK_MOUSE
NC score	0.165267 (rank : 448)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	458	Target Neighborhood Hits	1057	Shared Neighborhood Hits	118
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

LRIG2_MOUSE
NC score	0.165221 (rank : 449)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	458	Target Neighborhood Hits	586	Shared Neighborhood Hits	90
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG1_HUMAN
NC score	0.165097 (rank : 450)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	458	Target Neighborhood Hits	654	Shared Neighborhood Hits	88
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
NC score	0.163265 (rank : 451)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	458	Target Neighborhood Hits	627	Shared Neighborhood Hits	88
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

PTPRJ_MOUSE
NC score	0.163241 (rank : 452)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	458	Target Neighborhood Hits	188	Shared Neighborhood Hits	88
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

EPHA7_MOUSE
NC score	0.162976 (rank : 453)	θ value	4.1701e-05 (rank : 150)
Query Neighborhood Hits	458	Target Neighborhood Hits	1025	Shared Neighborhood Hits	190
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

TARSH_HUMAN
NC score	0.162879 (rank : 454)	θ value	1.81305 (rank : 373)
Query Neighborhood Hits	458	Target Neighborhood Hits	768	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MT1H_HUMAN
NC score	0.162159 (rank : 455)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	458	Target Neighborhood Hits	78	Shared Neighborhood Hits	45
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

EPHB4_MOUSE
NC score	0.161979 (rank : 456)	θ value	8.97725e-08 (rank : 96)
Query Neighborhood Hits	458	Target Neighborhood Hits	1013	Shared Neighborhood Hits	204
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

FCRL5_HUMAN
NC score	0.161694 (rank : 457)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	458	Target Neighborhood Hits	267	Shared Neighborhood Hits	62
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

JAM1_MOUSE
NC score	0.161563 (rank : 458)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	458	Target Neighborhood Hits	287	Shared Neighborhood Hits	72
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

LCE1D_HUMAN
NC score	0.160988 (rank : 459)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	458	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

BASI_MOUSE
NC score	0.160860 (rank : 460)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	458	Target Neighborhood Hits	238	Shared Neighborhood Hits	67
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

LRIG3_MOUSE
NC score	0.160702 (rank : 461)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	458	Target Neighborhood Hits	611	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

EPHA3_MOUSE
NC score	0.160661 (rank : 462)	θ value	4.92598e-06 (rank : 126)
Query Neighborhood Hits	458	Target Neighborhood Hits	1009	Shared Neighborhood Hits	194
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

KIRR3_HUMAN
NC score	0.160606 (rank : 463)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	458	Target Neighborhood Hits	302	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

HCFC2_HUMAN
NC score	0.159858 (rank : 464)	θ value	0.0431538 (rank : 257)
Query Neighborhood Hits	458	Target Neighborhood Hits	154	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

LYAM3_MOUSE
NC score	0.159824 (rank : 465)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	458	Target Neighborhood Hits	390	Shared Neighborhood Hits	169
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LRIG3_HUMAN
NC score	0.159724 (rank : 466)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	458	Target Neighborhood Hits	601	Shared Neighborhood Hits	91
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

KIRR1_HUMAN
NC score	0.159162 (rank : 467)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	458	Target Neighborhood Hits	401	Shared Neighborhood Hits	70
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

NFX1_HUMAN
NC score	0.158799 (rank : 468)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	458	Target Neighborhood Hits	405	Shared Neighborhood Hits	114
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

LCE1E_HUMAN
NC score	0.158792 (rank : 469)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	458	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

VSIG2_HUMAN
NC score	0.158176 (rank : 470)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	458	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

ANKF1_HUMAN
NC score	0.158115 (rank : 471)	θ value	9.29e-05 (rank : 158)
Query Neighborhood Hits	458	Target Neighborhood Hits	126	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

KIRR1_MOUSE
NC score	0.157599 (rank : 472)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	458	Target Neighborhood Hits	403	Shared Neighborhood Hits	70
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

EPHB3_HUMAN
NC score	0.157187 (rank : 473)	θ value	9.29e-05 (rank : 159)
Query Neighborhood Hits	458	Target Neighborhood Hits	996	Shared Neighborhood Hits	173
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHA4_MOUSE
NC score	0.157064 (rank : 474)	θ value	0.00035302 (rank : 182)
Query Neighborhood Hits	458	Target Neighborhood Hits	982	Shared Neighborhood Hits	168
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

KIRR3_MOUSE
NC score	0.157035 (rank : 475)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

EPHB3_MOUSE
NC score	0.156946 (rank : 476)	θ value	0.000121331 (rank : 162)
Query Neighborhood Hits	458	Target Neighborhood Hits	996	Shared Neighborhood Hits	163
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

CD22_HUMAN
NC score	0.156943 (rank : 477)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	458	Target Neighborhood Hits	365	Shared Neighborhood Hits	70
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CEAM5_HUMAN
NC score	0.156626 (rank : 478)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	458	Target Neighborhood Hits	343	Shared Neighborhood Hits	73
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

PCSK5_HUMAN
NC score	0.156557 (rank : 479)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	458	Target Neighborhood Hits	291	Shared Neighborhood Hits	150
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

EPHA3_HUMAN
NC score	0.156362 (rank : 480)	θ value	8.40245e-06 (rank : 132)
Query Neighborhood Hits	458	Target Neighborhood Hits	1005	Shared Neighborhood Hits	192
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA8_MOUSE
NC score	0.156273 (rank : 481)	θ value	0.000158464 (rank : 165)
Query Neighborhood Hits	458	Target Neighborhood Hits	969	Shared Neighborhood Hits	154
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

VWF_MOUSE
NC score	0.155928 (rank : 482)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	458	Target Neighborhood Hits	381	Shared Neighborhood Hits	153
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KR103_HUMAN
NC score	0.155483 (rank : 483)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	458	Target Neighborhood Hits	212	Shared Neighborhood Hits	108
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

EPHA4_HUMAN
NC score	0.155252 (rank : 484)	θ value	0.000270298 (rank : 176)
Query Neighborhood Hits	458	Target Neighborhood Hits	975	Shared Neighborhood Hits	160
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

MUC13_MOUSE
NC score	0.154070 (rank : 485)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	458	Target Neighborhood Hits	447	Shared Neighborhood Hits	143
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

EPHB2_HUMAN
NC score	0.153570 (rank : 486)	θ value	8.11959e-09 (rank : 73)
Query Neighborhood Hits	458	Target Neighborhood Hits	983	Shared Neighborhood Hits	165
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

MFA3L_HUMAN
NC score	0.153513 (rank : 487)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	458	Target Neighborhood Hits	230	Shared Neighborhood Hits	72
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

EPHB2_MOUSE
NC score	0.153494 (rank : 488)	θ value	8.11959e-09 (rank : 74)
Query Neighborhood Hits	458	Target Neighborhood Hits	982	Shared Neighborhood Hits	165
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHA8_HUMAN
NC score	0.153117 (rank : 489)	θ value	0.00298849 (rank : 213)
Query Neighborhood Hits	458	Target Neighborhood Hits	956	Shared Neighborhood Hits	152
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

TYRO3_HUMAN
NC score	0.152551 (rank : 490)	θ value	4.03905 (rank : 405)
Query Neighborhood Hits	458	Target Neighborhood Hits	995	Shared Neighborhood Hits	135
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

EPHA5_HUMAN
NC score	0.151737 (rank : 491)	θ value	6.43352e-06 (rank : 127)
Query Neighborhood Hits	458	Target Neighborhood Hits	1009	Shared Neighborhood Hits	175
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

KRA15_HUMAN
NC score	0.151712 (rank : 492)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	458	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

LCE1F_HUMAN
NC score	0.151688 (rank : 493)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	458	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

JAM2_HUMAN
NC score	0.151307 (rank : 494)	θ value	3.0926 (rank : 392)
Query Neighborhood Hits	458	Target Neighborhood Hits	304	Shared Neighborhood Hits	74
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

TDGF1_HUMAN
NC score	0.150866 (rank : 495)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	458	Target Neighborhood Hits	132	Shared Neighborhood Hits	100
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TYRO3_MOUSE
NC score	0.150131 (rank : 496)	θ value	0.365318 (rank : 324)
Query Neighborhood Hits	458	Target Neighborhood Hits	1007	Shared Neighborhood Hits	140
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

KR10A_HUMAN
NC score	0.149360 (rank : 497)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	458	Target Neighborhood Hits	232	Shared Neighborhood Hits	120
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

VSIG2_MOUSE
NC score	0.149215 (rank : 498)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	458	Target Neighborhood Hits	316	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

LYAM1_MOUSE
NC score	0.149128 (rank : 499)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	458	Target Neighborhood Hits	332	Shared Neighborhood Hits	156
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

FCRL2_HUMAN
NC score	0.148838 (rank : 500)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	458	Target Neighborhood Hits	251	Shared Neighborhood Hits	67
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

LCE1A_HUMAN
NC score	0.148665 (rank : 501)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	458	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

EPHB1_HUMAN
NC score	0.148432 (rank : 502)	θ value	0.0431538 (rank : 255)
Query Neighborhood Hits	458	Target Neighborhood Hits	988	Shared Neighborhood Hits	173
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

CSF3R_MOUSE
NC score	0.147459 (rank : 503)	θ value	6.88961 (rank : 424)
Query Neighborhood Hits	458	Target Neighborhood Hits	104	Shared Neighborhood Hits	72
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

ESM1_HUMAN
NC score	0.147153 (rank : 504)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	458	Target Neighborhood Hits	110	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

CEA20_HUMAN
NC score	0.146326 (rank : 505)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	458	Target Neighborhood Hits	251	Shared Neighborhood Hits	67
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

CEAM1_MOUSE
NC score	0.145766 (rank : 506)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	458	Target Neighborhood Hits	326	Shared Neighborhood Hits	68
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

EPHA6_HUMAN
NC score	0.145392 (rank : 507)	θ value	0.0431538 (rank : 254)
Query Neighborhood Hits	458	Target Neighborhood Hits	959	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

PTPRO_HUMAN
NC score	0.145207 (rank : 508)	θ value	0.47712 (rank : 330)
Query Neighborhood Hits	458	Target Neighborhood Hits	139	Shared Neighborhood Hits	58
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

TDGF2_HUMAN
NC score	0.143260 (rank : 509)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	458	Target Neighborhood Hits	131	Shared Neighborhood Hits	98
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

EPHA2_HUMAN
NC score	0.143147 (rank : 510)	θ value	0.00665767 (rank : 223)
Query Neighborhood Hits	458	Target Neighborhood Hits	1021	Shared Neighborhood Hits	179
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHAA_HUMAN
NC score	0.142131 (rank : 511)	θ value	1.81305 (rank : 370)
Query Neighborhood Hits	458	Target Neighborhood Hits	960	Shared Neighborhood Hits	150
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

LYAM1_HUMAN
NC score	0.141735 (rank : 512)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	458	Target Neighborhood Hits	315	Shared Neighborhood Hits	151
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

ELTD1_HUMAN
NC score	0.141568 (rank : 513)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	458	Target Neighborhood Hits	269	Shared Neighborhood Hits	135
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

JAM2_MOUSE
NC score	0.141123 (rank : 514)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	458	Target Neighborhood Hits	292	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

UFO_MOUSE
NC score	0.140823 (rank : 515)	θ value	0.00102713 (rank : 199)
Query Neighborhood Hits	458	Target Neighborhood Hits	988	Shared Neighborhood Hits	140
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

MT1F_HUMAN
NC score	0.140748 (rank : 516)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	41
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MERTK_HUMAN
NC score	0.140318 (rank : 517)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	458	Target Neighborhood Hits	988	Shared Neighborhood Hits	126
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

EPHA6_MOUSE
NC score	0.139575 (rank : 518)	θ value	0.0330416 (rank : 249)
Query Neighborhood Hits	458	Target Neighborhood Hits	946	Shared Neighborhood Hits	143
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

LYAM3_HUMAN
NC score	0.139531 (rank : 519)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	458	Target Neighborhood Hits	378	Shared Neighborhood Hits	171
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

EPHA2_MOUSE
NC score	0.139463 (rank : 520)	θ value	0.0113563 (rank : 231)
Query Neighborhood Hits	458	Target Neighborhood Hits	1020	Shared Neighborhood Hits	182
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

MERTK_MOUSE
NC score	0.138107 (rank : 521)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	458	Target Neighborhood Hits	974	Shared Neighborhood Hits	131
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

IGS4B_MOUSE
NC score	0.137748 (rank : 522)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	458	Target Neighborhood Hits	328	Shared Neighborhood Hits	67
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

UFO_HUMAN
NC score	0.137387 (rank : 523)	θ value	0.0563607 (rank : 268)
Query Neighborhood Hits	458	Target Neighborhood Hits	981	Shared Neighborhood Hits	145
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

VGFR1_HUMAN
NC score	0.136726 (rank : 524)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	458	Target Neighborhood Hits	1109	Shared Neighborhood Hits	116
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

SIG10_HUMAN
NC score	0.136612 (rank : 525)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	458	Target Neighborhood Hits	363	Shared Neighborhood Hits	72
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

SIG11_HUMAN
NC score	0.136345 (rank : 526)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	458	Target Neighborhood Hits	273	Shared Neighborhood Hits	74
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

MT1_MOUSE
NC score	0.136340 (rank : 527)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	458	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

IGS4B_HUMAN
NC score	0.136086 (rank : 528)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	458	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

VGFR1_MOUSE
NC score	0.135640 (rank : 529)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	458	Target Neighborhood Hits	1118	Shared Neighborhood Hits	117
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

MYLK_HUMAN
NC score	0.133748 (rank : 530)	θ value	0.279714 (rank : 314)
Query Neighborhood Hits	458	Target Neighborhood Hits	1328	Shared Neighborhood Hits	138
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

LCE3A_HUMAN
NC score	0.133479 (rank : 531)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	458	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

ROS_HUMAN
NC score	0.133340 (rank : 532)	θ value	7.59969e-07 (rank : 112)
Query Neighborhood Hits	458	Target Neighborhood Hits	907	Shared Neighborhood Hits	151
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

NRX1A_HUMAN
NC score	0.131881 (rank : 533)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	458	Target Neighborhood Hits	170	Shared Neighborhood Hits	103
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

MYLK_MOUSE
NC score	0.131757 (rank : 534)	θ value	5.27518 (rank : 417)
Query Neighborhood Hits	458	Target Neighborhood Hits	1489	Shared Neighborhood Hits	143
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

ATL3_HUMAN
NC score	0.131665 (rank : 535)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	458	Target Neighborhood Hits	414	Shared Neighborhood Hits	104
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

MFA3L_MOUSE
NC score	0.131092 (rank : 536)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	458	Target Neighborhood Hits	214	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

CEAM1_HUMAN
NC score	0.130657 (rank : 537)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	458	Target Neighborhood Hits	348	Shared Neighborhood Hits	70
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

VGFR2_HUMAN
NC score	0.130257 (rank : 538)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	458	Target Neighborhood Hits	1103	Shared Neighborhood Hits	117
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

FGFR4_MOUSE
NC score	0.129647 (rank : 539)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	458	Target Neighborhood Hits	1026	Shared Neighborhood Hits	117
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

NRX1A_MOUSE
NC score	0.129643 (rank : 540)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	458	Target Neighborhood Hits	164	Shared Neighborhood Hits	102
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

MUC2_HUMAN
NC score	0.129324 (rank : 541)	θ value	0.0961366 (rank : 286)
Query Neighborhood Hits	458	Target Neighborhood Hits	906	Shared Neighborhood Hits	153
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

VGFR2_MOUSE
NC score	0.129132 (rank : 542)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	458	Target Neighborhood Hits	1089	Shared Neighborhood Hits	116
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

CD45_HUMAN
NC score	0.128862 (rank : 543)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	458	Target Neighborhood Hits	243	Shared Neighborhood Hits	65
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PROC_MOUSE
NC score	0.128808 (rank : 544)	θ value	0.365318 (rank : 321)
Query Neighborhood Hits	458	Target Neighborhood Hits	426	Shared Neighborhood Hits	177
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

INSRR_HUMAN
NC score	0.128635 (rank : 545)	θ value	0.000270298 (rank : 178)
Query Neighborhood Hits	458	Target Neighborhood Hits	950	Shared Neighborhood Hits	164
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

FAT2_HUMAN
NC score	0.128058 (rank : 546)	θ value	5.27518 (rank : 413)
Query Neighborhood Hits	458	Target Neighborhood Hits	507	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

EPHA5_MOUSE
NC score	0.128031 (rank : 547)	θ value	0.00035302 (rank : 183)
Query Neighborhood Hits	458	Target Neighborhood Hits	950	Shared Neighborhood Hits	137
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

PGCB_MOUSE
NC score	0.127947 (rank : 548)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	458	Target Neighborhood Hits	459	Shared Neighborhood Hits	155
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

CD45_MOUSE
NC score	0.127779 (rank : 549)	θ value	0.00665767 (rank : 222)
Query Neighborhood Hits	458	Target Neighborhood Hits	178	Shared Neighborhood Hits	51
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

INSRR_MOUSE
NC score	0.126938 (rank : 550)	θ value	0.000270298 (rank : 179)
Query Neighborhood Hits	458	Target Neighborhood Hits	961	Shared Neighborhood Hits	172
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

FGFR4_HUMAN
NC score	0.126837 (rank : 551)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	458	Target Neighborhood Hits	1037	Shared Neighborhood Hits	116
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FA10_HUMAN
NC score	0.126116 (rank : 552)	θ value	3.0926 (rank : 387)
Query Neighborhood Hits	458	Target Neighborhood Hits	431	Shared Neighborhood Hits	172
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FGFR3_MOUSE
NC score	0.125638 (rank : 553)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	458	Target Neighborhood Hits	1059	Shared Neighborhood Hits	118
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

OBSCN_HUMAN
NC score	0.125147 (rank : 554)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	458	Target Neighborhood Hits	1931	Shared Neighborhood Hits	159
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ADA11_HUMAN
NC score	0.124198 (rank : 555)	θ value	0.21417 (rank : 304)
Query Neighborhood Hits	458	Target Neighborhood Hits	259	Shared Neighborhood Hits	157
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

MT1M_HUMAN
NC score	0.123972 (rank : 556)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	458	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MT1I_HUMAN
NC score	0.123745 (rank : 557)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	458	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

ADA11_MOUSE
NC score	0.123666 (rank : 558)	θ value	0.21417 (rank : 305)
Query Neighborhood Hits	458	Target Neighborhood Hits	263	Shared Neighborhood Hits	158
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

FGFR1_HUMAN
NC score	0.123646 (rank : 559)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	458	Target Neighborhood Hits	1069	Shared Neighborhood Hits	116
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

ADA15_MOUSE
NC score	0.123618 (rank : 560)	θ value	4.03905 (rank : 399)
Query Neighborhood Hits	458	Target Neighborhood Hits	324	Shared Neighborhood Hits	169
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

FA10_MOUSE
NC score	0.123516 (rank : 561)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	458	Target Neighborhood Hits	435	Shared Neighborhood Hits	170
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FGFR1_MOUSE
NC score	0.123485 (rank : 562)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	458	Target Neighborhood Hits	1068	Shared Neighborhood Hits	116
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

VSIG4_HUMAN
NC score	0.123353 (rank : 563)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

FGFR2_HUMAN
NC score	0.123322 (rank : 564)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	458	Target Neighborhood Hits	1062	Shared Neighborhood Hits	116
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

SPEG_MOUSE
NC score	0.123152 (rank : 565)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	458	Target Neighborhood Hits	1959	Shared Neighborhood Hits	151
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

FGFR3_HUMAN
NC score	0.122789 (rank : 566)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	458	Target Neighborhood Hits	1042	Shared Neighborhood Hits	116
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

EPHA1_HUMAN
NC score	0.122661 (rank : 567)	θ value	0.163984 (rank : 300)
Query Neighborhood Hits	458	Target Neighborhood Hits	997	Shared Neighborhood Hits	165
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

HGFA_HUMAN
NC score	0.122061 (rank : 568)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	458	Target Neighborhood Hits	436	Shared Neighborhood Hits	173
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

SPEG_HUMAN
NC score	0.122043 (rank : 569)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	458	Target Neighborhood Hits	1762	Shared Neighborhood Hits	150
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ADAM8_HUMAN
NC score	0.121995 (rank : 570)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	458	Target Neighborhood Hits	327	Shared Neighborhood Hits	153
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

NRX3A_HUMAN
NC score	0.121921 (rank : 571)	θ value	8.99809 (rank : 452)
Query Neighborhood Hits	458	Target Neighborhood Hits	164	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

LCE4A_HUMAN
NC score	0.121487 (rank : 572)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	458	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

PGCB_HUMAN
NC score	0.121450 (rank : 573)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	458	Target Neighborhood Hits	478	Shared Neighborhood Hits	152
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

NRX2A_HUMAN
NC score	0.121129 (rank : 574)	θ value	5.27518 (rank : 420)
Query Neighborhood Hits	458	Target Neighborhood Hits	614	Shared Neighborhood Hits	119
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

CILP2_HUMAN
NC score	0.121080 (rank : 575)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	458	Target Neighborhood Hits	307	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

ADAM8_MOUSE
NC score	0.120484 (rank : 576)	θ value	0.813845 (rank : 343)
Query Neighborhood Hits	458	Target Neighborhood Hits	326	Shared Neighborhood Hits	145
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

LRC21_MOUSE
NC score	0.119997 (rank : 577)	θ value	6.88961 (rank : 431)
Query Neighborhood Hits	458	Target Neighborhood Hits	462	Shared Neighborhood Hits	98
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

KRA42_HUMAN
NC score	0.119920 (rank : 578)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	458	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

ROR2_MOUSE
NC score	0.119715 (rank : 579)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	458	Target Neighborhood Hits	1000	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

EPHA1_MOUSE
NC score	0.119556 (rank : 580)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	458	Target Neighborhood Hits	958	Shared Neighborhood Hits	158
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

FGFR2_MOUSE
NC score	0.119308 (rank : 581)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	458	Target Neighborhood Hits	1062	Shared Neighborhood Hits	116
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

HGFA_MOUSE
NC score	0.117472 (rank : 582)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	458	Target Neighborhood Hits	419	Shared Neighborhood Hits	173
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

CD166_MOUSE
NC score	0.116986 (rank : 583)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	458	Target Neighborhood Hits	252	Shared Neighborhood Hits	62
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

LRFN4_HUMAN
NC score	0.116615 (rank : 584)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	458	Target Neighborhood Hits	462	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

MT1L_HUMAN
NC score	0.116585 (rank : 585)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1E_HUMAN
NC score	0.116582 (rank : 586)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	458	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

ADA15_HUMAN
NC score	0.116374 (rank : 587)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	458	Target Neighborhood Hits	288	Shared Neighborhood Hits	149
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

GPA33_HUMAN
NC score	0.116237 (rank : 588)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	458	Target Neighborhood Hits	273	Shared Neighborhood Hits	60
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

ROR2_HUMAN
NC score	0.116234 (rank : 589)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	458	Target Neighborhood Hits	1014	Shared Neighborhood Hits	119
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

LRC21_HUMAN
NC score	0.115925 (rank : 590)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	458	Target Neighborhood Hits	456	Shared Neighborhood Hits	94
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

I12R1_HUMAN
NC score	0.115548 (rank : 591)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	458	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

ADA17_HUMAN
NC score	0.115026 (rank : 592)	θ value	0.0736092 (rank : 269)
Query Neighborhood Hits	458	Target Neighborhood Hits	223	Shared Neighborhood Hits	98
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

NAC3_HUMAN
NC score	0.114626 (rank : 593)	θ value	1.69304e-06 (rank : 120)
Query Neighborhood Hits	458	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	P57103, Q8IUE9, Q8IUF0, Q8NFI7	Gene names	SLC8A3, NCX3
Domain Architecture
Description	Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3).

INSR_MOUSE
NC score	0.114598 (rank : 594)	θ value	0.0193708 (rank : 240)
Query Neighborhood Hits	458	Target Neighborhood Hits	968	Shared Neighborhood Hits	146
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

FA12_HUMAN
NC score	0.114124 (rank : 595)	θ value	3.0926 (rank : 388)
Query Neighborhood Hits	458	Target Neighborhood Hits	425	Shared Neighborhood Hits	168
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

IGF1R_MOUSE
NC score	0.113793 (rank : 596)	θ value	0.0193708 (rank : 239)
Query Neighborhood Hits	458	Target Neighborhood Hits	973	Shared Neighborhood Hits	158
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IL1R2_HUMAN
NC score	0.113746 (rank : 597)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	458	Target Neighborhood Hits	153	Shared Neighborhood Hits	53
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

GPA33_MOUSE
NC score	0.113472 (rank : 598)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	458	Target Neighborhood Hits	294	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

IGF1R_HUMAN
NC score	0.113434 (rank : 599)	θ value	0.0193708 (rank : 238)
Query Neighborhood Hits	458	Target Neighborhood Hits	977	Shared Neighborhood Hits	153
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KR410_HUMAN
NC score	0.113182 (rank : 600)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	458	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

IL27B_HUMAN
NC score	0.113042 (rank : 601)	θ value	3.0926 (rank : 390)
Query Neighborhood Hits	458	Target Neighborhood Hits	80	Shared Neighborhood Hits	56
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

INSR_HUMAN
NC score	0.112999 (rank : 602)	θ value	0.0431538 (rank : 258)
Query Neighborhood Hits	458	Target Neighborhood Hits	963	Shared Neighborhood Hits	148
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

UNC5D_MOUSE
NC score	0.112943 (rank : 603)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	458	Target Neighborhood Hits	268	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

VGFR3_HUMAN
NC score	0.112777 (rank : 604)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	458	Target Neighborhood Hits	1037	Shared Neighborhood Hits	115
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

HCFC1_MOUSE
NC score	0.112743 (rank : 605)	θ value	0.0961366 (rank : 280)
Query Neighborhood Hits	458	Target Neighborhood Hits	348	Shared Neighborhood Hits	74
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

ROR1_HUMAN
NC score	0.112375 (rank : 606)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	458	Target Neighborhood Hits	1018	Shared Neighborhood Hits	120
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

PTPRZ_HUMAN
NC score	0.112357 (rank : 607)	θ value	0.0193708 (rank : 241)
Query Neighborhood Hits	458	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

LRFN4_MOUSE
NC score	0.112294 (rank : 608)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	458	Target Neighborhood Hits	442	Shared Neighborhood Hits	86
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

PROC_HUMAN
NC score	0.111978 (rank : 609)	θ value	2.36792 (rank : 378)
Query Neighborhood Hits	458	Target Neighborhood Hits	406	Shared Neighborhood Hits	171
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

SIGL5_MOUSE
NC score	0.111422 (rank : 610)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	458	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

LRFN2_MOUSE
NC score	0.111253 (rank : 611)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	458	Target Neighborhood Hits	450	Shared Neighborhood Hits	84
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

PCSK6_HUMAN
NC score	0.111167 (rank : 612)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	458	Target Neighborhood Hits	298	Shared Neighborhood Hits	132
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

DUET_HUMAN
NC score	0.111061 (rank : 613)	θ value	1.87187e-05 (rank : 139)
Query Neighborhood Hits	458	Target Neighborhood Hits	1220	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

VGFR3_MOUSE
NC score	0.110971 (rank : 614)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	458	Target Neighborhood Hits	1056	Shared Neighborhood Hits	117
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

ROR1_MOUSE
NC score	0.110963 (rank : 615)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	458	Target Neighborhood Hits	1025	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ADA28_HUMAN
NC score	0.110718 (rank : 616)	θ value	0.62314 (rank : 333)
Query Neighborhood Hits	458	Target Neighborhood Hits	244	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

FA9_HUMAN
NC score	0.110715 (rank : 617)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	458	Target Neighborhood Hits	421	Shared Neighborhood Hits	159
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

UNC5D_HUMAN
NC score	0.110040 (rank : 618)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	458	Target Neighborhood Hits	267	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ADA19_MOUSE
NC score	0.110029 (rank : 619)	θ value	0.0148317 (rank : 232)
Query Neighborhood Hits	458	Target Neighborhood Hits	315	Shared Neighborhood Hits	167
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA23_HUMAN
NC score	0.109837 (rank : 620)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	458	Target Neighborhood Hits	235	Shared Neighborhood Hits	141
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CEAM6_HUMAN
NC score	0.109663 (rank : 621)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	458	Target Neighborhood Hits	308	Shared Neighborhood Hits	71
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

NAC1_HUMAN
NC score	0.109424 (rank : 622)	θ value	9.29e-05 (rank : 160)
Query Neighborhood Hits	458	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	P32418, O95849, Q9UBL8, Q9UDN1, Q9UDN2, Q9UKX6	Gene names	SLC8A1, CNC, NCX1
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

VEGFC_HUMAN
NC score	0.109418 (rank : 623)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	458	Target Neighborhood Hits	128	Shared Neighborhood Hits	76
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADA18_MOUSE
NC score	0.109322 (rank : 624)	θ value	0.62314 (rank : 332)
Query Neighborhood Hits	458	Target Neighborhood Hits	227	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

LRFN2_HUMAN
NC score	0.109309 (rank : 625)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	458	Target Neighborhood Hits	450	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

NTRK3_HUMAN
NC score	0.109251 (rank : 626)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	458	Target Neighborhood Hits	1115	Shared Neighborhood Hits	122
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

NTRK2_HUMAN
NC score	0.109140 (rank : 627)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	458	Target Neighborhood Hits	1081	Shared Neighborhood Hits	118
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

I12R1_MOUSE
NC score	0.109137 (rank : 628)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	458	Target Neighborhood Hits	70	Shared Neighborhood Hits	53
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

RECK_HUMAN
NC score	0.109120 (rank : 629)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	458	Target Neighborhood Hits	189	Shared Neighborhood Hits	84
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

DKK3_MOUSE
NC score	0.108995 (rank : 630)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

DKK3_HUMAN
NC score	0.108933 (rank : 631)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	458	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

NTRK2_MOUSE
NC score	0.108273 (rank : 632)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	458	Target Neighborhood Hits	1088	Shared Neighborhood Hits	119
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

CRLF1_HUMAN
NC score	0.108224 (rank : 633)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	458	Target Neighborhood Hits	122	Shared Neighborhood Hits	75
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

LRFN3_MOUSE
NC score	0.108085 (rank : 634)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	458	Target Neighborhood Hits	455	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

NAC1_MOUSE
NC score	0.108031 (rank : 635)	θ value	0.00020696 (rank : 174)
Query Neighborhood Hits	458	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	P70414	Gene names	Slc8a1, Ncx
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

CSF1R_MOUSE
NC score	0.107696 (rank : 636)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	458	Target Neighborhood Hits	983	Shared Neighborhood Hits	110
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

ADAM9_MOUSE
NC score	0.107041 (rank : 637)	θ value	0.21417 (rank : 306)
Query Neighborhood Hits	458	Target Neighborhood Hits	325	Shared Neighborhood Hits	152
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

FSTL3_HUMAN
NC score	0.107008 (rank : 638)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	458	Target Neighborhood Hits	162	Shared Neighborhood Hits	74
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

PTPRE_MOUSE
NC score	0.106959 (rank : 639)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	458	Target Neighborhood Hits	86	Shared Neighborhood Hits	16
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

LORI_MOUSE
NC score	0.106835 (rank : 640)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	458	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

PTPRE_HUMAN
NC score	0.106726 (rank : 641)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	458	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

NAC2_HUMAN
NC score	0.106715 (rank : 642)	θ value	0.000158464 (rank : 168)
Query Neighborhood Hits	458	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPR5	Gene names	SLC8A2, KIAA1087, NCX2
Domain Architecture
Description	Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2).

MT2_HUMAN
NC score	0.106666 (rank : 643)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	458	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

CRLF1_MOUSE
NC score	0.106646 (rank : 644)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	458	Target Neighborhood Hits	116	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

PTPRA_HUMAN
NC score	0.106615 (rank : 645)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	458	Target Neighborhood Hits	101	Shared Neighborhood Hits	18
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

MT1X_HUMAN
NC score	0.106484 (rank : 646)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	458	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

PTPRA_MOUSE
NC score	0.106310 (rank : 647)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	458	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRG_HUMAN
NC score	0.106175 (rank : 648)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	55
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

ESM1_MOUSE
NC score	0.106113 (rank : 649)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	458	Target Neighborhood Hits	107	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ADA17_MOUSE
NC score	0.105954 (rank : 650)	θ value	0.47712 (rank : 325)
Query Neighborhood Hits	458	Target Neighborhood Hits	201	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

CNTP2_MOUSE
NC score	0.105845 (rank : 651)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	109
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

ADA23_MOUSE
NC score	0.105840 (rank : 652)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	148
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

GPR98_HUMAN
NC score	0.105599 (rank : 653)	θ value	7.59969e-07 (rank : 111)
Query Neighborhood Hits	458	Target Neighborhood Hits	202	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

PTPRG_MOUSE
NC score	0.105435 (rank : 654)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	458	Target Neighborhood Hits	260	Shared Neighborhood Hits	54
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

CNTP2_HUMAN
NC score	0.105120 (rank : 655)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	458	Target Neighborhood Hits	199	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

FA7_HUMAN
NC score	0.105027 (rank : 656)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	458	Target Neighborhood Hits	404	Shared Neighborhood Hits	158
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

ADA19_HUMAN
NC score	0.104776 (rank : 657)	θ value	0.0563607 (rank : 262)
Query Neighborhood Hits	458	Target Neighborhood Hits	381	Shared Neighborhood Hits	155
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

CD166_HUMAN
NC score	0.104513 (rank : 658)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	458	Target Neighborhood Hits	247	Shared Neighborhood Hits	58
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

GPR98_MOUSE
NC score	0.103601 (rank : 659)	θ value	1.43324e-05 (rank : 135)
Query Neighborhood Hits	458	Target Neighborhood Hits	206	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

MMRN1_HUMAN
NC score	0.103471 (rank : 660)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	458	Target Neighborhood Hits	636	Shared Neighborhood Hits	121
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

UROL1_MOUSE
NC score	0.103264 (rank : 661)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	458	Target Neighborhood Hits	235	Shared Neighborhood Hits	118
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

LRFN3_HUMAN
NC score	0.102989 (rank : 662)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	458	Target Neighborhood Hits	444	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

UNC5A_HUMAN
NC score	0.102724 (rank : 663)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	458	Target Neighborhood Hits	198	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

CNTP4_MOUSE
NC score	0.102551 (rank : 664)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	458	Target Neighborhood Hits	193	Shared Neighborhood Hits	106
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ADA22_MOUSE
NC score	0.102294 (rank : 665)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	458	Target Neighborhood Hits	225	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA33_MOUSE
NC score	0.100909 (rank : 666)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	134
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CNTP4_HUMAN
NC score	0.100885 (rank : 667)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	458	Target Neighborhood Hits	187	Shared Neighborhood Hits	99
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

PGFRA_MOUSE
NC score	0.100656 (rank : 668)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	458	Target Neighborhood Hits	975	Shared Neighborhood Hits	111
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

RIMB2_HUMAN
NC score	0.100519 (rank : 669)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	458	Target Neighborhood Hits	263	Shared Neighborhood Hits	56
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

PGFRA_HUMAN
NC score	0.100334 (rank : 670)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	458	Target Neighborhood Hits	980	Shared Neighborhood Hits	110
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

EMR3_HUMAN
NC score	0.100062 (rank : 671)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

HCFC1_HUMAN
NC score	0.099800 (rank : 672)	θ value	0.0431538 (rank : 256)
Query Neighborhood Hits	458	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

PGCA_HUMAN
NC score	0.099570 (rank : 673)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	458	Target Neighborhood Hits	821	Shared Neighborhood Hits	167
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

VEGFC_MOUSE
NC score	0.098824 (rank : 674)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	458	Target Neighborhood Hits	119	Shared Neighborhood Hits	74
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADA28_MOUSE
NC score	0.098713 (rank : 675)	θ value	0.0961366 (rank : 278)
Query Neighborhood Hits	458	Target Neighborhood Hits	241	Shared Neighborhood Hits	122
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

PSG3_HUMAN
NC score	0.098438 (rank : 676)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	458	Target Neighborhood Hits	242	Shared Neighborhood Hits	66
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

LRFN5_MOUSE
NC score	0.098391 (rank : 677)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	458	Target Neighborhood Hits	472	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRRN1_HUMAN
NC score	0.098165 (rank : 678)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	458	Target Neighborhood Hits	518	Shared Neighborhood Hits	93
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

KIT_MOUSE
NC score	0.097831 (rank : 679)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	458	Target Neighborhood Hits	949	Shared Neighborhood Hits	106
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

ADA24_MOUSE
NC score	0.097606 (rank : 680)	θ value	0.279714 (rank : 311)
Query Neighborhood Hits	458	Target Neighborhood Hits	230	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

TNR25_HUMAN
NC score	0.097470 (rank : 681)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	458	Target Neighborhood Hits	172	Shared Neighborhood Hits	70
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

APR3_MOUSE
NC score	0.097230 (rank : 682)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	458	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ADA22_HUMAN
NC score	0.097098 (rank : 683)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	458	Target Neighborhood Hits	211	Shared Neighborhood Hits	119
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

BMPER_MOUSE
NC score	0.097047 (rank : 684)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

PSG4_HUMAN
NC score	0.096931 (rank : 685)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	458	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

FREM2_MOUSE
NC score	0.096815 (rank : 686)	θ value	6.43352e-06 (rank : 128)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

ADAM9_HUMAN
NC score	0.096537 (rank : 687)	θ value	0.62314 (rank : 335)
Query Neighborhood Hits	458	Target Neighborhood Hits	243	Shared Neighborhood Hits	132
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

CT075_HUMAN
NC score	0.096526 (rank : 688)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	458	Target Neighborhood Hits	387	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

LRFN5_HUMAN
NC score	0.096364 (rank : 689)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	458	Target Neighborhood Hits	464	Shared Neighborhood Hits	78
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

RIMB2_MOUSE
NC score	0.096204 (rank : 690)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	458	Target Neighborhood Hits	246	Shared Neighborhood Hits	49
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ADAM2_MOUSE
NC score	0.095816 (rank : 691)	θ value	1.81305 (rank : 367)
Query Neighborhood Hits	458	Target Neighborhood Hits	209	Shared Neighborhood Hits	119
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

UROL1_HUMAN
NC score	0.095585 (rank : 692)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	458	Target Neighborhood Hits	213	Shared Neighborhood Hits	103
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

CXAR_HUMAN
NC score	0.095455 (rank : 693)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	52
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

PGFRB_MOUSE
NC score	0.095353 (rank : 694)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	458	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

UNC5C_MOUSE
NC score	0.095311 (rank : 695)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	458	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.095307 (rank : 696)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	458	Target Neighborhood Hits	226	Shared Neighborhood Hits	69
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

CO6_HUMAN
NC score	0.095225 (rank : 697)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	458	Target Neighborhood Hits	331	Shared Neighborhood Hits	118
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

PERT_HUMAN
NC score	0.095195 (rank : 698)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	458	Target Neighborhood Hits	221	Shared Neighborhood Hits	103
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

LRRN1_MOUSE
NC score	0.095012 (rank : 699)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	458	Target Neighborhood Hits	508	Shared Neighborhood Hits	92
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

IL1R2_MOUSE
NC score	0.094755 (rank : 700)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	458	Target Neighborhood Hits	125	Shared Neighborhood Hits	44
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

ADA33_HUMAN
NC score	0.094667 (rank : 701)	θ value	0.62314 (rank : 334)
Query Neighborhood Hits	458	Target Neighborhood Hits	264	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CEAM8_HUMAN
NC score	0.094577 (rank : 702)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	458	Target Neighborhood Hits	264	Shared Neighborhood Hits	67
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

ADA10_HUMAN
NC score	0.094267 (rank : 703)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	458	Target Neighborhood Hits	189	Shared Neighborhood Hits	90
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA18_HUMAN
NC score	0.094175 (rank : 704)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	458	Target Neighborhood Hits	184	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

PSG8_HUMAN
NC score	0.094037 (rank : 705)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	458	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

ADA10_MOUSE
NC score	0.093843 (rank : 706)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	88
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

CNTP3_HUMAN
NC score	0.093640 (rank : 707)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	458	Target Neighborhood Hits	195	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CD276_HUMAN
NC score	0.093602 (rank : 708)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	458	Target Neighborhood Hits	261	Shared Neighborhood Hits	49
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

FREM2_HUMAN
NC score	0.093579 (rank : 709)	θ value	0.000121331 (rank : 163)
Query Neighborhood Hits	458	Target Neighborhood Hits	76	Shared Neighborhood Hits	18
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

ESAM_HUMAN
NC score	0.093551 (rank : 710)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	458	Target Neighborhood Hits	251	Shared Neighborhood Hits	62
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

KIT_HUMAN
NC score	0.093460 (rank : 711)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	458	Target Neighborhood Hits	953	Shared Neighborhood Hits	107
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

CILP1_HUMAN
NC score	0.093333 (rank : 712)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	458	Target Neighborhood Hits	266	Shared Neighborhood Hits	82
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

UNC5B_HUMAN
NC score	0.092996 (rank : 713)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	458	Target Neighborhood Hits	225	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

FREM3_HUMAN
NC score	0.092849 (rank : 714)	θ value	0.000158464 (rank : 166)
Query Neighborhood Hits	458	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

CO7_HUMAN
NC score	0.092460 (rank : 715)	θ value	3.0926 (rank : 383)
Query Neighborhood Hits	458	Target Neighborhood Hits	278	Shared Neighborhood Hits	108
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

MFGM_HUMAN
NC score	0.092269 (rank : 716)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	458	Target Neighborhood Hits	150	Shared Neighborhood Hits	94
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

UNC5B_MOUSE
NC score	0.092256 (rank : 717)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	458	Target Neighborhood Hits	226	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

FREM3_MOUSE
NC score	0.092093 (rank : 718)	θ value	0.000602161 (rank : 188)
Query Neighborhood Hits	458	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

PSG1_HUMAN
NC score	0.091793 (rank : 719)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	458	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

LRP6_HUMAN
NC score	0.091727 (rank : 720)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	458	Target Neighborhood Hits	235	Shared Neighborhood Hits	103
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

KR413_HUMAN
NC score	0.091474 (rank : 721)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	458	Target Neighborhood Hits	112	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

IRPL2_HUMAN
NC score	0.091393 (rank : 722)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	458	Target Neighborhood Hits	194	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

UNC5A_MOUSE
NC score	0.091360 (rank : 723)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	458	Target Neighborhood Hits	203	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

IRPL2_MOUSE
NC score	0.091147 (rank : 724)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	458	Target Neighborhood Hits	195	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

CILP1_MOUSE
NC score	0.091057 (rank : 725)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	458	Target Neighborhood Hits	282	Shared Neighborhood Hits	78
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

RECK_MOUSE
NC score	0.090900 (rank : 726)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	458	Target Neighborhood Hits	158	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

PGH2_MOUSE
NC score	0.090827 (rank : 727)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	458	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PSG7_HUMAN
NC score	0.090806 (rank : 728)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	458	Target Neighborhood Hits	239	Shared Neighborhood Hits	61
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

LRRN3_HUMAN
NC score	0.090799 (rank : 729)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	458	Target Neighborhood Hits	461	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

PGFRB_HUMAN
NC score	0.090730 (rank : 730)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	458	Target Neighborhood Hits	962	Shared Neighborhood Hits	110
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PSG11_HUMAN
NC score	0.090301 (rank : 731)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	458	Target Neighborhood Hits	223	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

BMPER_HUMAN
NC score	0.089878 (rank : 732)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	458	Target Neighborhood Hits	175	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

I27RA_HUMAN
NC score	0.089573 (rank : 733)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	458	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

ESAM_MOUSE
NC score	0.088573 (rank : 734)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	458	Target Neighborhood Hits	222	Shared Neighborhood Hits	54
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

CXAR_MOUSE
NC score	0.088207 (rank : 735)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	458	Target Neighborhood Hits	250	Shared Neighborhood Hits	55
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

KRA24_HUMAN
NC score	0.088078 (rank : 736)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	458	Target Neighborhood Hits	192	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

CNTP1_HUMAN
NC score	0.088076 (rank : 737)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	458	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

PSG6_HUMAN
NC score	0.088057 (rank : 738)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	59
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

PSG10_HUMAN
NC score	0.087834 (rank : 739)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	458	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

MUC13_HUMAN
NC score	0.087675 (rank : 740)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	458	Target Neighborhood Hits	164	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

LRP6_MOUSE
NC score	0.087517 (rank : 741)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	458	Target Neighborhood Hits	232	Shared Neighborhood Hits	99
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

IRPL1_MOUSE
NC score	0.087389 (rank : 742)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	458	Target Neighborhood Hits	186	Shared Neighborhood Hits	60
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

LCE2C_HUMAN
NC score	0.087147 (rank : 743)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	458	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

FA7_MOUSE
NC score	0.086492 (rank : 744)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	458	Target Neighborhood Hits	374	Shared Neighborhood Hits	136
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

SMDF_HUMAN
NC score	0.086404 (rank : 745)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	458	Target Neighborhood Hits	117	Shared Neighborhood Hits	57
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

ADA32_MOUSE
NC score	0.086390 (rank : 746)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	116
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_HUMAN
NC score	0.086385 (rank : 747)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	458	Target Neighborhood Hits	216	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CSF1R_HUMAN
NC score	0.086304 (rank : 748)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	458	Target Neighborhood Hits	943	Shared Neighborhood Hits	101
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

TNR16_HUMAN
NC score	0.086185 (rank : 749)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	458	Target Neighborhood Hits	183	Shared Neighborhood Hits	90
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

PSG2_HUMAN
NC score	0.085776 (rank : 750)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	458	Target Neighborhood Hits	229	Shared Neighborhood Hits	61
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

PERT_MOUSE
NC score	0.085703 (rank : 751)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	458	Target Neighborhood Hits	221	Shared Neighborhood Hits	97
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

APR3_HUMAN
NC score	0.085498 (rank : 752)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

PTN7_MOUSE
NC score	0.085423 (rank : 753)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	458	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

LRRN3_MOUSE
NC score	0.085415 (rank : 754)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	458	Target Neighborhood Hits	455	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

PTN7_HUMAN
NC score	0.085389 (rank : 755)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	458	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN9_MOUSE
NC score	0.085293 (rank : 756)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	458	Target Neighborhood Hits	78	Shared Neighborhood Hits	16
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN5_MOUSE
NC score	0.085291 (rank : 757)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	458	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.085194 (rank : 758)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	458	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN9_HUMAN
NC score	0.084960 (rank : 759)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	458	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

CORIN_HUMAN
NC score	0.084922 (rank : 760)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	458	Target Neighborhood Hits	453	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CNTP1_MOUSE
NC score	0.084906 (rank : 761)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	458	Target Neighborhood Hits	183	Shared Neighborhood Hits	92
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

LRP5_MOUSE
NC score	0.084799 (rank : 762)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	100
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

FSTL3_MOUSE
NC score	0.084515 (rank : 763)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	458	Target Neighborhood Hits	152	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

MKS3_MOUSE
NC score	0.084020 (rank : 764)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	458	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

PTN2_HUMAN
NC score	0.083689 (rank : 765)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	458	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

SIGL5_HUMAN
NC score	0.083482 (rank : 766)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	458	Target Neighborhood Hits	246	Shared Neighborhood Hits	60
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

PTPRR_HUMAN
NC score	0.083324 (rank : 767)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	458	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PGH2_HUMAN
NC score	0.083310 (rank : 768)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	458	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PTPRR_MOUSE
NC score	0.083090 (rank : 769)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	458	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTN2_MOUSE
NC score	0.082988 (rank : 770)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	458	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTPR2_MOUSE
NC score	0.082978 (rank : 771)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	458	Target Neighborhood Hits	120	Shared Neighborhood Hits	18
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPR2_HUMAN
NC score	0.082935 (rank : 772)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	458	Target Neighborhood Hits	103	Shared Neighborhood Hits	17
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

LRRN5_HUMAN
NC score	0.082780 (rank : 773)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	458	Target Neighborhood Hits	493	Shared Neighborhood Hits	80
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

IGS21_HUMAN
NC score	0.082736 (rank : 774)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	458	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

PTN18_MOUSE
NC score	0.082718 (rank : 775)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	458	Target Neighborhood Hits	134	Shared Neighborhood Hits	18
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTPRN_HUMAN
NC score	0.082430 (rank : 776)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	458	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

LRP5_HUMAN
NC score	0.082377 (rank : 777)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	458	Target Neighborhood Hits	224	Shared Neighborhood Hits	96
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

PTN22_HUMAN
NC score	0.082342 (rank : 778)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	458	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTPRN_MOUSE
NC score	0.082255 (rank : 779)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	458	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTN1_MOUSE
NC score	0.082241 (rank : 780)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	458	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN1_HUMAN
NC score	0.082221 (rank : 781)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	458	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

NTRK1_HUMAN
NC score	0.082181 (rank : 782)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	458	Target Neighborhood Hits	1023	Shared Neighborhood Hits	104
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

PIGR_HUMAN
NC score	0.082110 (rank : 783)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	458	Target Neighborhood Hits	164	Shared Neighborhood Hits	47
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

CO8B_MOUSE
NC score	0.082072 (rank : 784)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	458	Target Neighborhood Hits	224	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

SIGL8_HUMAN
NC score	0.081852 (rank : 785)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	458	Target Neighborhood Hits	252	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

PTN12_HUMAN
NC score	0.081681 (rank : 786)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

CRAC1_MOUSE
NC score	0.081388 (rank : 787)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	458	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

MEP1A_MOUSE
NC score	0.081300 (rank : 788)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	458	Target Neighborhood Hits	166	Shared Neighborhood Hits	101
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

IRPL1_HUMAN
NC score	0.081101 (rank : 789)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	458	Target Neighborhood Hits	196	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

PTN18_HUMAN
NC score	0.081060 (rank : 790)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN12_MOUSE
NC score	0.080934 (rank : 791)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	458	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

ADA30_HUMAN
NC score	0.080860 (rank : 792)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	458	Target Neighborhood Hits	391	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

LCE2D_HUMAN
NC score	0.080667 (rank : 793)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

CORIN_MOUSE
NC score	0.080621 (rank : 794)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	458	Target Neighborhood Hits	451	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

PTN22_MOUSE
NC score	0.080569 (rank : 795)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	458	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

CRAC1_HUMAN
NC score	0.080406 (rank : 796)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	458	Target Neighborhood Hits	111	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

MATN1_HUMAN
NC score	0.079920 (rank : 797)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	458	Target Neighborhood Hits	191	Shared Neighborhood Hits	86
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

TECTA_MOUSE
NC score	0.079605 (rank : 798)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	458	Target Neighborhood Hits	244	Shared Neighborhood Hits	116
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

PSG9_HUMAN
NC score	0.079338 (rank : 799)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	458	Target Neighborhood Hits	221	Shared Neighborhood Hits	58
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

LRC24_HUMAN
NC score	0.079118 (rank : 800)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	458	Target Neighborhood Hits	404	Shared Neighborhood Hits	75
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

MATN1_MOUSE
NC score	0.079110 (rank : 801)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	458	Target Neighborhood Hits	186	Shared Neighborhood Hits	83
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

IGS21_MOUSE
NC score	0.078742 (rank : 802)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	458	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

ADAM7_HUMAN
NC score	0.078538 (rank : 803)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	458	Target Neighborhood Hits	221	Shared Neighborhood Hits	127
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

PGH1_MOUSE
NC score	0.078410 (rank : 804)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	458	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PDL1_HUMAN
NC score	0.078182 (rank : 805)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	458	Target Neighborhood Hits	195	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

ADAM2_HUMAN
NC score	0.077938 (rank : 806)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	458	Target Neighborhood Hits	175	Shared Neighborhood Hits	94
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADA12_HUMAN
NC score	0.077805 (rank : 807)	θ value	1.81305 (rank : 366)
Query Neighborhood Hits	458	Target Neighborhood Hits	224	Shared Neighborhood Hits	109
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

LEPR_HUMAN
NC score	0.077619 (rank : 808)	θ value	0.0563607 (rank : 266)
Query Neighborhood Hits	458	Target Neighborhood Hits	112	Shared Neighborhood Hits	57
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

ERBB3_HUMAN
NC score	0.077571 (rank : 809)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	458	Target Neighborhood Hits	918	Shared Neighborhood Hits	106
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

CT075_MOUSE
NC score	0.077243 (rank : 810)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	458	Target Neighborhood Hits	358	Shared Neighborhood Hits	64
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

IL6RA_MOUSE
NC score	0.077100 (rank : 811)	θ value	0.0252991 (rank : 245)
Query Neighborhood Hits	458	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

MCSP_MOUSE
NC score	0.076864 (rank : 812)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	458	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

FST_MOUSE
NC score	0.076844 (rank : 813)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	458	Target Neighborhood Hits	146	Shared Neighborhood Hits	59
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

NRG4_HUMAN
NC score	0.076841 (rank : 814)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	458	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PTN6_HUMAN
NC score	0.076789 (rank : 815)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	458	Target Neighborhood Hits	234	Shared Neighborhood Hits	18
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PIGR_MOUSE
NC score	0.076783 (rank : 816)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	458	Target Neighborhood Hits	214	Shared Neighborhood Hits	47
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

EMB_MOUSE
NC score	0.076727 (rank : 817)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

PTN6_MOUSE
NC score	0.076707 (rank : 818)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	458	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

MOX2R_MOUSE
NC score	0.076423 (rank : 819)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	458	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

PSG5_HUMAN
NC score	0.076393 (rank : 820)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	458	Target Neighborhood Hits	231	Shared Neighborhood Hits	61
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

VASN_HUMAN
NC score	0.076096 (rank : 821)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	458	Target Neighborhood Hits	449	Shared Neighborhood Hits	116
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ILRL2_MOUSE
NC score	0.076006 (rank : 822)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	458	Target Neighborhood Hits	158	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

FCN3_HUMAN
NC score	0.075737 (rank : 823)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	458	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

MKS3_HUMAN
NC score	0.075420 (rank : 824)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	458	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

FCN1_MOUSE
NC score	0.075401 (rank : 825)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	458	Target Neighborhood Hits	173	Shared Neighborhood Hits	14
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN2_HUMAN
NC score	0.075318 (rank : 826)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	458	Target Neighborhood Hits	122	Shared Neighborhood Hits	13
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

MFAP4_MOUSE
NC score	0.074989 (rank : 827)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	458	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_HUMAN
NC score	0.074859 (rank : 828)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	458	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

ADA25_MOUSE
NC score	0.074828 (rank : 829)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	458	Target Neighborhood Hits	213	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

FCN1_HUMAN
NC score	0.074721 (rank : 830)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	458	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

LCE2A_HUMAN
NC score	0.074645 (rank : 831)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

PTN11_MOUSE
NC score	0.074629 (rank : 832)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	458	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.074626 (rank : 833)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	458	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

MEP1A_HUMAN
NC score	0.074524 (rank : 834)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	458	Target Neighborhood Hits	162	Shared Neighborhood Hits	95
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

LCE2B_HUMAN
NC score	0.074476 (rank : 835)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

ERBB4_HUMAN
NC score	0.074278 (rank : 836)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	458	Target Neighborhood Hits	910	Shared Neighborhood Hits	102
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

TNR16_MOUSE
NC score	0.073741 (rank : 837)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	458	Target Neighborhood Hits	178	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

ZN330_HUMAN
NC score	0.073425 (rank : 838)	θ value	0.163984 (rank : 303)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ADA21_MOUSE
NC score	0.073159 (rank : 839)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	458	Target Neighborhood Hits	172	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

FST_HUMAN
NC score	0.073081 (rank : 840)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	458	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADM1A_MOUSE
NC score	0.073058 (rank : 841)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	458	Target Neighborhood Hits	230	Shared Neighborhood Hits	122
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

NRG4_MOUSE
NC score	0.073014 (rank : 842)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	458	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

ADA12_MOUSE
NC score	0.072895 (rank : 843)	θ value	4.03905 (rank : 398)
Query Neighborhood Hits	458	Target Neighborhood Hits	474	Shared Neighborhood Hits	111
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

PECA1_HUMAN
NC score	0.072784 (rank : 844)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	458	Target Neighborhood Hits	178	Shared Neighborhood Hits	48
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

FLT3_MOUSE
NC score	0.072379 (rank : 845)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	458	Target Neighborhood Hits	847	Shared Neighborhood Hits	79
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

RYK_HUMAN
NC score	0.072173 (rank : 846)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	458	Target Neighborhood Hits	701	Shared Neighborhood Hits	48
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

AD26A_MOUSE
NC score	0.072138 (rank : 847)	θ value	0.163984 (rank : 296)
Query Neighborhood Hits	458	Target Neighborhood Hits	165	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ZN330_MOUSE
NC score	0.071986 (rank : 848)	θ value	0.21417 (rank : 310)
Query Neighborhood Hits	458	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	Q922H9, Q8C389, Q8K2M4	Gene names	Znf330, Noa36, Zfp330
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

SIG12_HUMAN
NC score	0.071942 (rank : 849)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	69
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

ERBB3_MOUSE
NC score	0.071860 (rank : 850)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	458	Target Neighborhood Hits	898	Shared Neighborhood Hits	95
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

VASN_MOUSE
NC score	0.071473 (rank : 851)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	458	Target Neighborhood Hits	426	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

EGFR_MOUSE
NC score	0.071429 (rank : 852)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	458	Target Neighborhood Hits	927	Shared Neighborhood Hits	109
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ADM1B_MOUSE
NC score	0.071389 (rank : 853)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	109
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

EGFR_HUMAN
NC score	0.071246 (rank : 854)	θ value	6.88961 (rank : 426)
Query Neighborhood Hits	458	Target Neighborhood Hits	939	Shared Neighborhood Hits	103
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

BMP1_MOUSE
NC score	0.071129 (rank : 855)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	103
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

EMR4_MOUSE
NC score	0.071128 (rank : 856)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	458	Target Neighborhood Hits	191	Shared Neighborhood Hits	90
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

RYK_MOUSE
NC score	0.071008 (rank : 857)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	458	Target Neighborhood Hits	715	Shared Neighborhood Hits	48
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

ERBB2_HUMAN
NC score	0.070545 (rank : 858)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	458	Target Neighborhood Hits	1073	Shared Neighborhood Hits	98
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

TECTA_HUMAN
NC score	0.070489 (rank : 859)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	458	Target Neighborhood Hits	239	Shared Neighborhood Hits	107
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

IL1R1_MOUSE
NC score	0.070483 (rank : 860)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	458	Target Neighborhood Hits	142	Shared Neighborhood Hits	53
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

IL1R1_HUMAN
NC score	0.070481 (rank : 861)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	458	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

LTK_MOUSE
NC score	0.070357 (rank : 862)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	458	Target Neighborhood Hits	770	Shared Neighborhood Hits	54
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

BMP1_HUMAN
NC score	0.070315 (rank : 863)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	458	Target Neighborhood Hits	233	Shared Neighborhood Hits	102
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

LTK_HUMAN
NC score	0.070193 (rank : 864)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	458	Target Neighborhood Hits	774	Shared Neighborhood Hits	53
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

ALK_MOUSE
NC score	0.070119 (rank : 865)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	458	Target Neighborhood Hits	811	Shared Neighborhood Hits	69
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

PTN23_MOUSE
NC score	0.069988 (rank : 866)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	458	Target Neighborhood Hits	726	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

ALK_HUMAN
NC score	0.069668 (rank : 867)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	458	Target Neighborhood Hits	795	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

LRC24_MOUSE
NC score	0.069602 (rank : 868)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	458	Target Neighborhood Hits	387	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

PGFRL_HUMAN
NC score	0.069225 (rank : 869)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	458	Target Neighborhood Hits	115	Shared Neighborhood Hits	46
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PTN23_HUMAN
NC score	0.069126 (rank : 870)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	458	Target Neighborhood Hits	646	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

ANGL7_MOUSE
NC score	0.069096 (rank : 871)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	458	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

TLL1_MOUSE
NC score	0.069059 (rank : 872)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	458	Target Neighborhood Hits	237	Shared Neighborhood Hits	100
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

ANGL6_MOUSE
NC score	0.068988 (rank : 873)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	458	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

TNR4_MOUSE
NC score	0.068879 (rank : 874)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	458	Target Neighborhood Hits	137	Shared Neighborhood Hits	62
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

ANGL7_HUMAN
NC score	0.068801 (rank : 875)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	458	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

ERBB2_MOUSE
NC score	0.068456 (rank : 876)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	458	Target Neighborhood Hits	918	Shared Neighborhood Hits	90
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

FGL1_HUMAN
NC score	0.068434 (rank : 877)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	458	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q08830, Q4PJH9, Q96KW6, Q96QM6	Gene names	FGL1, HFREP1
Domain Architecture
Description	Fibrinogen-like protein 1 precursor (Hepatocyte-derived fibrinogen- related protein 1) (HFREP-1) (Hepassocin) (HP-041).

ADAM7_MOUSE
NC score	0.068268 (rank : 878)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	458	Target Neighborhood Hits	200	Shared Neighborhood Hits	105
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

TLL2_HUMAN
NC score	0.068266 (rank : 879)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	458	Target Neighborhood Hits	241	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ANGL5_HUMAN
NC score	0.068022 (rank : 880)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	458	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

SIGL6_HUMAN
NC score	0.067790 (rank : 881)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	458	Target Neighborhood Hits	233	Shared Neighborhood Hits	64
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

CLC14_HUMAN
NC score	0.067704 (rank : 882)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	458	Target Neighborhood Hits	143	Shared Neighborhood Hits	72
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

FGL2_MOUSE
NC score	0.067671 (rank : 883)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

ANGL6_HUMAN
NC score	0.067615 (rank : 884)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	458	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

LRC4B_MOUSE
NC score	0.067481 (rank : 885)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	458	Target Neighborhood Hits	484	Shared Neighborhood Hits	71
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

ADA21_HUMAN
NC score	0.066955 (rank : 886)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	458	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

TNR9_HUMAN
NC score	0.066658 (rank : 887)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	458	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

FGL2_HUMAN
NC score	0.066521 (rank : 888)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	458	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

TLL1_HUMAN
NC score	0.066497 (rank : 889)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	458	Target Neighborhood Hits	236	Shared Neighborhood Hits	98
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

FIBA_HUMAN
NC score	0.066416 (rank : 890)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	458	Target Neighborhood Hits	132	Shared Neighborhood Hits	12
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

LRC4B_HUMAN
NC score	0.066301 (rank : 891)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	458	Target Neighborhood Hits	479	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

DDR1_HUMAN
NC score	0.066243 (rank : 892)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	458	Target Neighborhood Hits	819	Shared Neighborhood Hits	55
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

PGH1_HUMAN
NC score	0.066204 (rank : 893)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	458	Target Neighborhood Hits	91	Shared Neighborhood Hits	58
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

RSPO4_HUMAN
NC score	0.066126 (rank : 894)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	458	Target Neighborhood Hits	110	Shared Neighborhood Hits	57
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

EREG_HUMAN
NC score	0.066108 (rank : 895)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	458	Target Neighborhood Hits	73	Shared Neighborhood Hits	44
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

TNR4_HUMAN
NC score	0.065950 (rank : 896)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	458	Target Neighborhood Hits	152	Shared Neighborhood Hits	63
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

WFDC3_HUMAN
NC score	0.065684 (rank : 897)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	458	Target Neighborhood Hits	138	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

MT1G_HUMAN
NC score	0.065601 (rank : 898)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	458	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

PTN14_HUMAN
NC score	0.065572 (rank : 899)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	458	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

TNR14_HUMAN
NC score	0.065524 (rank : 900)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	458	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

PDL2_MOUSE
NC score	0.065472 (rank : 901)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	458	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

CLC14_MOUSE
NC score	0.065293 (rank : 902)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	458	Target Neighborhood Hits	120	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

DDR1_MOUSE
NC score	0.065123 (rank : 903)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	458	Target Neighborhood Hits	818	Shared Neighborhood Hits	54
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

FIBB_MOUSE
NC score	0.064862 (rank : 904)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	458	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

PTN14_MOUSE
NC score	0.064820 (rank : 905)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	458	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

FLT3_HUMAN
NC score	0.064779 (rank : 906)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	458	Target Neighborhood Hits	843	Shared Neighborhood Hits	65
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

DDR2_HUMAN
NC score	0.064777 (rank : 907)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	458	Target Neighborhood Hits	818	Shared Neighborhood Hits	54
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

PTN21_MOUSE
NC score	0.064667 (rank : 908)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	458	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

FIBB_HUMAN
NC score	0.064664 (rank : 909)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	458	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

NGL1_MOUSE
NC score	0.064633 (rank : 910)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	458	Target Neighborhood Hits	512	Shared Neighborhood Hits	72
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_HUMAN
NC score	0.064516 (rank : 911)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	458	Target Neighborhood Hits	511	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

ANGL2_MOUSE
NC score	0.064383 (rank : 912)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	458	Target Neighborhood Hits	108	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL2_HUMAN
NC score	0.064330 (rank : 913)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	458	Target Neighborhood Hits	104	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

PTN21_HUMAN
NC score	0.064292 (rank : 914)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	458	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

ILRL1_HUMAN
NC score	0.064129 (rank : 915)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	458	Target Neighborhood Hits	167	Shared Neighborhood Hits	47
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

DDR2_MOUSE
NC score	0.064054 (rank : 916)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	458	Target Neighborhood Hits	813	Shared Neighborhood Hits	53
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

ANGL1_MOUSE
NC score	0.063842 (rank : 917)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

LRP3_HUMAN
NC score	0.063704 (rank : 918)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	458	Target Neighborhood Hits	280	Shared Neighborhood Hits	90
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

STYK1_MOUSE
NC score	0.063460 (rank : 919)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	458	Target Neighborhood Hits	779	Shared Neighborhood Hits	51
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

LRP10_HUMAN
NC score	0.063419 (rank : 920)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	458	Target Neighborhood Hits	197	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

ANGL1_HUMAN
NC score	0.063394 (rank : 921)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	458	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	O95841, Q5T5Z5	Gene names	ANGPTL1, ANG3, ANGPT3, ARP1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1) (Angiopoietin-3) (ANG-3).

ANGP4_HUMAN
NC score	0.063374 (rank : 922)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	458	Target Neighborhood Hits	187	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

CSPG4_HUMAN
NC score	0.063368 (rank : 923)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	458	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

ADA29_HUMAN
NC score	0.063342 (rank : 924)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	458	Target Neighborhood Hits	247	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

TLL2_MOUSE
NC score	0.063336 (rank : 925)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	458	Target Neighborhood Hits	240	Shared Neighborhood Hits	100
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CD79A_HUMAN
NC score	0.063106 (rank : 926)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	458	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

JAML1_MOUSE
NC score	0.062963 (rank : 927)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	458	Target Neighborhood Hits	185	Shared Neighborhood Hits	40
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

TNK1_HUMAN
NC score	0.062900 (rank : 928)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	458	Target Neighborhood Hits	815	Shared Neighborhood Hits	51
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

PTN3_HUMAN
NC score	0.062846 (rank : 929)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	458	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

TNR23_MOUSE
NC score	0.062604 (rank : 930)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	458	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

FAK2_HUMAN
NC score	0.062407 (rank : 931)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	458	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

ANGL4_MOUSE
NC score	0.062285 (rank : 932)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	458	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

LRRC4_HUMAN
NC score	0.062251 (rank : 933)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	458	Target Neighborhood Hits	444	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

PTN4_HUMAN
NC score	0.062179 (rank : 934)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	458	Target Neighborhood Hits	303	Shared Neighborhood Hits	21
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

I11RB_MOUSE
NC score	0.062063 (rank : 935)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	458	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

CSPG4_MOUSE
NC score	0.062059 (rank : 936)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	458	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

FAK2_MOUSE
NC score	0.061939 (rank : 937)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	458	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

TNK1_MOUSE
NC score	0.061923 (rank : 938)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	458	Target Neighborhood Hits	806	Shared Neighborhood Hits	53
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TPA_MOUSE
NC score	0.061912 (rank : 939)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	458	Target Neighborhood Hits	335	Shared Neighborhood Hits	122
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ANGL4_HUMAN
NC score	0.061691 (rank : 940)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	458	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

FAK1_HUMAN
NC score	0.061567 (rank : 941)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	458	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

RET_MOUSE
NC score	0.061464 (rank : 942)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	458	Target Neighborhood Hits	884	Shared Neighborhood Hits	68
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

FAK1_MOUSE
NC score	0.061436 (rank : 943)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	458	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

STYK1_HUMAN
NC score	0.061098 (rank : 944)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	458	Target Neighborhood Hits	786	Shared Neighborhood Hits	52
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

ANGP1_HUMAN
NC score	0.061076 (rank : 945)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	458	Target Neighborhood Hits	254	Shared Neighborhood Hits	14
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP4_MOUSE
NC score	0.060910 (rank : 946)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	458	Target Neighborhood Hits	220	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

RET_HUMAN
NC score	0.060806 (rank : 947)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	458	Target Neighborhood Hits	873	Shared Neighborhood Hits	60
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

TPA_HUMAN
NC score	0.060777 (rank : 948)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	458	Target Neighborhood Hits	324	Shared Neighborhood Hits	118
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

MET_MOUSE
NC score	0.060764 (rank : 949)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	458	Target Neighborhood Hits	844	Shared Neighborhood Hits	55
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

ZNFX1_MOUSE
NC score	0.060558 (rank : 950)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	458	Target Neighborhood Hits	407	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ILK1_HUMAN
NC score	0.060537 (rank : 951)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	458	Target Neighborhood Hits	857	Shared Neighborhood Hits	57
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ACK1_MOUSE
NC score	0.060512 (rank : 952)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	458	Target Neighborhood Hits	1080	Shared Neighborhood Hits	61
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

MET_HUMAN
NC score	0.060470 (rank : 953)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	458	Target Neighborhood Hits	831	Shared Neighborhood Hits	50
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

ILK_MOUSE
NC score	0.060458 (rank : 954)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	458	Target Neighborhood Hits	858	Shared Neighborhood Hits	56
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ZAP70_HUMAN
NC score	0.060443 (rank : 955)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	458	Target Neighborhood Hits	893	Shared Neighborhood Hits	51
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
NC score	0.060432 (rank : 956)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	458	Target Neighborhood Hits	905	Shared Neighborhood Hits	50
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ILK2_HUMAN
NC score	0.060424 (rank : 957)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	458	Target Neighborhood Hits	848	Shared Neighborhood Hits	56
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

SHBG_HUMAN
NC score	0.060340 (rank : 958)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	458	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

ANGL3_MOUSE
NC score	0.060223 (rank : 959)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	458	Target Neighborhood Hits	306	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ANGP1_MOUSE
NC score	0.060220 (rank : 960)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	458	Target Neighborhood Hits	252	Shared Neighborhood Hits	13
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

PVRL3_MOUSE
NC score	0.060050 (rank : 961)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	458	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

TRIO_HUMAN
NC score	0.059845 (rank : 962)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	458	Target Neighborhood Hits	1580	Shared Neighborhood Hits	124
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

RSPO3_HUMAN
NC score	0.059677 (rank : 963)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	458	Target Neighborhood Hits	128	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

ACK1_HUMAN
NC score	0.059573 (rank : 964)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	458	Target Neighborhood Hits	1140	Shared Neighborhood Hits	60
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

RON_MOUSE
NC score	0.059520 (rank : 965)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	458	Target Neighborhood Hits	836	Shared Neighborhood Hits	56
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

FREM1_HUMAN
NC score	0.059490 (rank : 966)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	458	Target Neighborhood Hits	170	Shared Neighborhood Hits	24
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FIBG_MOUSE
NC score	0.059415 (rank : 967)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	458	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM7, Q8WUR3, Q91ZP0	Gene names	Fgg
Domain Architecture	No domain graphic available
Description	Fibrinogen gamma chain precursor.

ST14_MOUSE
NC score	0.059358 (rank : 968)	θ value	0.62314 (rank : 342)
Query Neighborhood Hits	458	Target Neighborhood Hits	419	Shared Neighborhood Hits	123
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

LCE3B_HUMAN
NC score	0.059239 (rank : 969)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	458	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

PDL1_MOUSE
NC score	0.059171 (rank : 970)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	458	Target Neighborhood Hits	168	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

LEPR_MOUSE
NC score	0.059013 (rank : 971)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	458	Target Neighborhood Hits	109	Shared Neighborhood Hits	53
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

FIBG_HUMAN
NC score	0.059011 (rank : 972)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	458	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P02679, P04469, P04470, Q96A14, Q96KJ3	Gene names	FGG
Domain Architecture
Description	Fibrinogen gamma chain precursor.

CD276_MOUSE
NC score	0.058669 (rank : 973)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	458	Target Neighborhood Hits	243	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

KSYK_HUMAN
NC score	0.058601 (rank : 974)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	458	Target Neighborhood Hits	901	Shared Neighborhood Hits	51
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LCE5A_HUMAN
NC score	0.058593 (rank : 975)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	458	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

KSYK_MOUSE
NC score	0.058592 (rank : 976)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	458	Target Neighborhood Hits	944	Shared Neighborhood Hits	51
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

ST14_HUMAN
NC score	0.058519 (rank : 977)	θ value	2.36792 (rank : 379)
Query Neighborhood Hits	458	Target Neighborhood Hits	409	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

SPY1_MOUSE
NC score	0.058402 (rank : 978)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	458	Target Neighborhood Hits	57	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

RON_HUMAN
NC score	0.058375 (rank : 979)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	458	Target Neighborhood Hits	842	Shared Neighborhood Hits	54
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

CO8A_HUMAN
NC score	0.057934 (rank : 980)	θ value	6.88961 (rank : 423)
Query Neighborhood Hits	458	Target Neighborhood Hits	200	Shared Neighborhood Hits	77
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

AATK_MOUSE
NC score	0.057900 (rank : 981)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	458	Target Neighborhood Hits	942	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

RSPO3_MOUSE
NC score	0.057765 (rank : 982)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	458	Target Neighborhood Hits	120	Shared Neighborhood Hits	54
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

PTN13_MOUSE
NC score	0.057758 (rank : 983)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	458	Target Neighborhood Hits	426	Shared Neighborhood Hits	21
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

CEAM7_HUMAN
NC score	0.057734 (rank : 984)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	458	Target Neighborhood Hits	170	Shared Neighborhood Hits	52
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

SHBG_MOUSE
NC score	0.057633 (rank : 985)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	458	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

FREM1_MOUSE
NC score	0.057247 (rank : 986)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	458	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FES_MOUSE
NC score	0.057004 (rank : 987)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	458	Target Neighborhood Hits	980	Shared Neighborhood Hits	53
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_HUMAN
NC score	0.057001 (rank : 988)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	458	Target Neighborhood Hits	978	Shared Neighborhood Hits	51
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

PVRL1_HUMAN
NC score	0.056945 (rank : 989)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	458	Target Neighborhood Hits	219	Shared Neighborhood Hits	39
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

PTN13_HUMAN
NC score	0.056789 (rank : 990)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	458	Target Neighborhood Hits	471	Shared Neighborhood Hits	21
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PECA1_MOUSE
NC score	0.056586 (rank : 991)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	458	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

SRMS_HUMAN
NC score	0.056457 (rank : 992)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	458	Target Neighborhood Hits	946	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

TNR7_HUMAN
NC score	0.056395 (rank : 993)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	458	Target Neighborhood Hits	120	Shared Neighborhood Hits	51
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

ANGP2_HUMAN
NC score	0.056383 (rank : 994)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	458	Target Neighborhood Hits	400	Shared Neighborhood Hits	12
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

LRP10_MOUSE
NC score	0.056238 (rank : 995)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	458	Target Neighborhood Hits	169	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

AATK_HUMAN
NC score	0.056209 (rank : 996)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	458	Target Neighborhood Hits	1243	Shared Neighborhood Hits	61
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

CO8B_HUMAN
NC score	0.055992 (rank : 997)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	458	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

MATK_HUMAN
NC score	0.055979 (rank : 998)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	458	Target Neighborhood Hits	954	Shared Neighborhood Hits	50
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

ANGL3_HUMAN
NC score	0.055968 (rank : 999)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	458	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

TXK_MOUSE
NC score	0.055863 (rank : 1000)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	458	Target Neighborhood Hits	980	Shared Neighborhood Hits	50
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

FER_HUMAN
NC score	0.055841 (rank : 1001)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	458	Target Neighborhood Hits	1278	Shared Neighborhood Hits	56
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

ANGP2_MOUSE
NC score	0.055794 (rank : 1002)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	458	Target Neighborhood Hits	397	Shared Neighborhood Hits	13
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

MATK_MOUSE
NC score	0.055737 (rank : 1003)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	458	Target Neighborhood Hits	952	Shared Neighborhood Hits	50
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

TNR26_MOUSE
NC score	0.055565 (rank : 1004)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	458	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

ASTN_MOUSE
NC score	0.055560 (rank : 1005)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	458	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

HCK_MOUSE
NC score	0.055480 (rank : 1006)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	458	Target Neighborhood Hits	1029	Shared Neighborhood Hits	50
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

TRIM9_HUMAN
NC score	0.055471 (rank : 1007)	θ value	1.38821 (rank : 364)
Query Neighborhood Hits	458	Target Neighborhood Hits	294	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

SRMS_MOUSE
NC score	0.055436 (rank : 1008)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	458	Target Neighborhood Hits	964	Shared Neighborhood Hits	50
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

TXK_HUMAN
NC score	0.055224 (rank : 1009)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	458	Target Neighborhood Hits	971	Shared Neighborhood Hits	50
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

HCK_HUMAN
NC score	0.055172 (rank : 1010)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	458	Target Neighborhood Hits	1035	Shared Neighborhood Hits	51
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

LCK_HUMAN
NC score	0.055152 (rank : 1011)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	458	Target Neighborhood Hits	987	Shared Neighborhood Hits	52
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

ITK_MOUSE
NC score	0.055111 (rank : 1012)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	458	Target Neighborhood Hits	985	Shared Neighborhood Hits	53
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

LCK_MOUSE
NC score	0.055104 (rank : 1013)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	458	Target Neighborhood Hits	981	Shared Neighborhood Hits	50
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

HHLA2_HUMAN
NC score	0.055090 (rank : 1014)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	458	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

BMX_MOUSE
NC score	0.055066 (rank : 1015)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	458	Target Neighborhood Hits	912	Shared Neighborhood Hits	51
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BLK_MOUSE
NC score	0.055018 (rank : 1016)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	458	Target Neighborhood Hits	992	Shared Neighborhood Hits	50
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

ITK_HUMAN
NC score	0.055017 (rank : 1017)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	458	Target Neighborhood Hits	1016	Shared Neighborhood Hits	53
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

YES_HUMAN
NC score	0.054876 (rank : 1018)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	458	Target Neighborhood Hits	1059	Shared Neighborhood Hits	52
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

PVRL3_HUMAN
NC score	0.054720 (rank : 1019)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	458	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

YES_MOUSE
NC score	0.054689 (rank : 1020)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	458	Target Neighborhood Hits	1052	Shared Neighborhood Hits	51
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

RSPO4_MOUSE
NC score	0.054611 (rank : 1021)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	458	Target Neighborhood Hits	110	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

BMX_HUMAN
NC score	0.054611 (rank : 1022)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	458	Target Neighborhood Hits	942	Shared Neighborhood Hits	52
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

TNR9_MOUSE
NC score	0.054588 (rank : 1023)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	458	Target Neighborhood Hits	137	Shared Neighborhood Hits	56
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

EPGN_MOUSE
NC score	0.054574 (rank : 1024)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	458	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

CO9_MOUSE
NC score	0.054503 (rank : 1025)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	458	Target Neighborhood Hits	153	Shared Neighborhood Hits	65
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

BLK_HUMAN
NC score	0.054451 (rank : 1026)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	458	Target Neighborhood Hits	994	Shared Neighborhood Hits	50
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

TEC_HUMAN
NC score	0.054439 (rank : 1027)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	458	Target Neighborhood Hits	1006	Shared Neighborhood Hits	50
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

I11RA_MOUSE
NC score	0.054347 (rank : 1028)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	458	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

TEC_MOUSE
NC score	0.054333 (rank : 1029)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	458	Target Neighborhood Hits	1006	Shared Neighborhood Hits	50
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

SRC_MOUSE
NC score	0.054304 (rank : 1030)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	458	Target Neighborhood Hits	1033	Shared Neighborhood Hits	51
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

LYN_MOUSE
NC score	0.054255 (rank : 1031)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	458	Target Neighborhood Hits	1023	Shared Neighborhood Hits	50
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

BTK_MOUSE
NC score	0.054248 (rank : 1032)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	458	Target Neighborhood Hits	1017	Shared Neighborhood Hits	51
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

BTK_HUMAN
NC score	0.054188 (rank : 1033)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	458	Target Neighborhood Hits	1026	Shared Neighborhood Hits	51
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

ABL1_MOUSE
NC score	0.054183 (rank : 1034)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	458	Target Neighborhood Hits	1178	Shared Neighborhood Hits	56
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

LYN_HUMAN
NC score	0.054143 (rank : 1035)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	458	Target Neighborhood Hits	1022	Shared Neighborhood Hits	50
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

FGR_HUMAN
NC score	0.054124 (rank : 1036)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	458	Target Neighborhood Hits	1067	Shared Neighborhood Hits	50
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

EPGN_HUMAN
NC score	0.054123 (rank : 1037)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	458	Target Neighborhood Hits	59	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

FGR_MOUSE
NC score	0.053996 (rank : 1038)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	458	Target Neighborhood Hits	1069	Shared Neighborhood Hits	50
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FRK_HUMAN
NC score	0.053993 (rank : 1039)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	458	Target Neighborhood Hits	1058	Shared Neighborhood Hits	50
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

ABL1_HUMAN
NC score	0.053669 (rank : 1040)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	458	Target Neighborhood Hits	1220	Shared Neighborhood Hits	52
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SRC_HUMAN
NC score	0.053657 (rank : 1041)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	458	Target Neighborhood Hits	1058	Shared Neighborhood Hits	50
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

ASTN_HUMAN
NC score	0.053641 (rank : 1042)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	458	Target Neighborhood Hits	105	Shared Neighborhood Hits	49
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

LRRC4_MOUSE
NC score	0.053542 (rank : 1043)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	458	Target Neighborhood Hits	412	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

ABL2_HUMAN
NC score	0.053494 (rank : 1044)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	458	Target Neighborhood Hits	1045	Shared Neighborhood Hits	49
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

PVRL1_MOUSE
NC score	0.053492 (rank : 1045)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	458	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

LRP12_HUMAN
NC score	0.053410 (rank : 1046)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	458	Target Neighborhood Hits	205	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

I11RA_HUMAN
NC score	0.053380 (rank : 1047)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	458	Target Neighborhood Hits	138	Shared Neighborhood Hits	44
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

LCE3C_HUMAN
NC score	0.053354 (rank : 1048)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	458	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

FYN_MOUSE
NC score	0.053258 (rank : 1049)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	458	Target Neighborhood Hits	1073	Shared Neighborhood Hits	51
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

CSK_HUMAN
NC score	0.052743 (rank : 1050)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	458	Target Neighborhood Hits	1009	Shared Neighborhood Hits	50
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

PVR_HUMAN
NC score	0.052675 (rank : 1051)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	458	Target Neighborhood Hits	195	Shared Neighborhood Hits	41
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

CD320_HUMAN
NC score	0.052674 (rank : 1052)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	458	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

FYN_HUMAN
NC score	0.052674 (rank : 1053)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	458	Target Neighborhood Hits	1078	Shared Neighborhood Hits	51
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

PTK6_MOUSE
NC score	0.052634 (rank : 1054)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	458	Target Neighborhood Hits	1026	Shared Neighborhood Hits	50
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

ODFP_MOUSE
NC score	0.052544 (rank : 1055)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	458	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

CO8A_MOUSE
NC score	0.052379 (rank : 1056)	θ value	1.81305 (rank : 369)
Query Neighborhood Hits	458	Target Neighborhood Hits	182	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

FCERA_HUMAN
NC score	0.052186 (rank : 1057)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	458	Target Neighborhood Hits	150	Shared Neighborhood Hits	39
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

CSK_MOUSE
NC score	0.051724 (rank : 1058)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	458	Target Neighborhood Hits	1009	Shared Neighborhood Hits	50
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

PTK6_HUMAN
NC score	0.051487 (rank : 1059)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	458	Target Neighborhood Hits	1020	Shared Neighborhood Hits	50
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

TRIM9_MOUSE
NC score	0.051473 (rank : 1060)	θ value	0.365318 (rank : 323)
Query Neighborhood Hits	458	Target Neighborhood Hits	274	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

JAK1_MOUSE
NC score	0.051274 (rank : 1061)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	458	Target Neighborhood Hits	854	Shared Neighborhood Hits	50
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

PGFRL_MOUSE
NC score	0.051263 (rank : 1062)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	458	Target Neighborhood Hits	106	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

JAK1_HUMAN
NC score	0.051191 (rank : 1063)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	458	Target Neighborhood Hits	858	Shared Neighborhood Hits	50
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

FCGR1_HUMAN
NC score	0.051146 (rank : 1064)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	458	Target Neighborhood Hits	145	Shared Neighborhood Hits	43
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

GUC2C_HUMAN
NC score	0.050929 (rank : 1065)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	458	Target Neighborhood Hits	624	Shared Neighborhood Hits	42
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

TEX14_HUMAN
NC score	0.050885 (rank : 1066)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	458	Target Neighborhood Hits	1103	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

LRP12_MOUSE
NC score	0.050758 (rank : 1067)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	458	Target Neighborhood Hits	180	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

GUC2F_HUMAN
NC score	0.050474 (rank : 1068)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	458	Target Neighborhood Hits	740	Shared Neighborhood Hits	49
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

MEP1B_MOUSE
NC score	0.050216 (rank : 1069)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	458	Target Neighborhood Hits	127	Shared Neighborhood Hits	68
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

TNR22_MOUSE
NC score	0.050162 (rank : 1070)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	458	Target Neighborhood Hits	97	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

MLKL_HUMAN
NC score	0.050111 (rank : 1071)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	458	Target Neighborhood Hits	600	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MGAT3_HUMAN
NC score	0.041205 (rank : 1072)	θ value	0.813845 (rank : 347)
Query Neighborhood Hits	458	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q09327, Q6IC49, Q9UH32	Gene names	MGAT3, GGNT3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

MGAT3_MOUSE
NC score	0.038520 (rank : 1073)	θ value	0.813845 (rank : 348)
Query Neighborhood Hits	458	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q10470, P70386	Gene names	Mgat3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

HTRA3_HUMAN
NC score	0.033820 (rank : 1074)	θ value	5.27518 (rank : 415)
Query Neighborhood Hits	458	Target Neighborhood Hits	152	Shared Neighborhood Hits	24
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
NC score	0.033809 (rank : 1075)	θ value	0.62314 (rank : 339)
Query Neighborhood Hits	458	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

MLL3_MOUSE
NC score	0.031134 (rank : 1076)	θ value	2.36792 (rank : 377)
Query Neighborhood Hits	458	Target Neighborhood Hits	1399	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TYRP1_HUMAN
NC score	0.030433 (rank : 1077)	θ value	6.88961 (rank : 434)
Query Neighborhood Hits	458	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

PP16A_MOUSE
NC score	0.029293 (rank : 1078)	θ value	0.0431538 (rank : 260)
Query Neighborhood Hits	458	Target Neighborhood Hits	318	Shared Neighborhood Hits	11
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

UHMK1_MOUSE
NC score	0.026915 (rank : 1079)	θ value	6.88961 (rank : 435)
Query Neighborhood Hits	458	Target Neighborhood Hits	809	Shared Neighborhood Hits	46
SwissProt Accessions	P97343, Q61775, Q9CYT1	Gene names	Uhmk1, Kis, Kist
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

IL4RA_HUMAN
NC score	0.026245 (rank : 1080)	θ value	3.0926 (rank : 391)
Query Neighborhood Hits	458	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

MLL3_HUMAN
NC score	0.025190 (rank : 1081)	θ value	0.365318 (rank : 319)
Query Neighborhood Hits	458	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SLK_HUMAN
NC score	0.023939 (rank : 1082)	θ value	0.62314 (rank : 341)
Query Neighborhood Hits	458	Target Neighborhood Hits	1775	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SLK_MOUSE
NC score	0.023173 (rank : 1083)	θ value	1.38821 (rank : 363)
Query Neighborhood Hits	458	Target Neighborhood Hits	1798	Shared Neighborhood Hits	62
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

DKK2_MOUSE
NC score	0.022739 (rank : 1084)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	458	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QYZ8	Gene names	Dkk2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (mDkk-2).

PMYT1_MOUSE
NC score	0.022513 (rank : 1085)	θ value	3.0926 (rank : 396)
Query Neighborhood Hits	458	Target Neighborhood Hits	910	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ESG9, Q8R3L4	Gene names	Pkmyt1, Myt1
Domain Architecture	No domain graphic available
Description	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase).

DKK2_HUMAN
NC score	0.021965 (rank : 1086)	θ value	8.99809 (rank : 440)
Query Neighborhood Hits	458	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBU2, Q9UIU3	Gene names	DKK2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (hDkk-2).

TRI36_MOUSE
NC score	0.020635 (rank : 1087)	θ value	8.99809 (rank : 456)
Query Neighborhood Hits	458	Target Neighborhood Hits	266	Shared Neighborhood Hits	33
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI36_HUMAN
NC score	0.020490 (rank : 1088)	θ value	0.813845 (rank : 351)
Query Neighborhood Hits	458	Target Neighborhood Hits	282	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

CHK1_HUMAN
NC score	0.019204 (rank : 1089)	θ value	8.99809 (rank : 439)
Query Neighborhood Hits	458	Target Neighborhood Hits	843	Shared Neighborhood Hits	50
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

CO4A2_HUMAN
NC score	0.017765 (rank : 1090)	θ value	5.27518 (rank : 410)
Query Neighborhood Hits	458	Target Neighborhood Hits	454	Shared Neighborhood Hits	17
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

UB7I1_MOUSE
NC score	0.017705 (rank : 1091)	θ value	2.36792 (rank : 381)
Query Neighborhood Hits	458	Target Neighborhood Hits	206	Shared Neighborhood Hits	12
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UB7I1_HUMAN
NC score	0.016401 (rank : 1092)	θ value	2.36792 (rank : 380)
Query Neighborhood Hits	458	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

DNJA1_MOUSE
NC score	0.014160 (rank : 1093)	θ value	0.0736092 (rank : 271)
Query Neighborhood Hits	458	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	P63037, P54102	Gene names	Dnaja1, Dnaj2, Hsj2, Hspf4
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2).

DNJA1_HUMAN
NC score	0.014040 (rank : 1094)	θ value	0.0736092 (rank : 270)
Query Neighborhood Hits	458	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	P31689	Gene names	DNAJA1, DNAJ2, HDJ2, HSJ2, HSPF4
Domain Architecture
Description	DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2) (HSDJ).

ATS8_MOUSE
NC score	0.013979 (rank : 1095)	θ value	4.03905 (rank : 400)
Query Neighborhood Hits	458	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

PODXL_HUMAN
NC score	0.012899 (rank : 1096)	θ value	8.99809 (rank : 453)
Query Neighborhood Hits	458	Target Neighborhood Hits	191	Shared Neighborhood Hits	15
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PCD16_HUMAN
NC score	0.012796 (rank : 1097)	θ value	1.38821 (rank : 362)
Query Neighborhood Hits	458	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

MAP4_HUMAN
NC score	0.011764 (rank : 1098)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	458	Target Neighborhood Hits	428	Shared Neighborhood Hits	18
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CD68_HUMAN
NC score	0.011611 (rank : 1099)	θ value	3.0926 (rank : 382)
Query Neighborhood Hits	458	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	P34810, Q96BI7	Gene names	CD68
Domain Architecture
Description	Macrosialin precursor (GP110) (CD68 antigen).

BORG1_HUMAN
NC score	0.011042 (rank : 1100)	θ value	1.81305 (rank : 368)
Query Neighborhood Hits	458	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

PAR10_HUMAN
NC score	0.010947 (rank : 1101)	θ value	4.03905 (rank : 404)
Query Neighborhood Hits	458	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

TARA_HUMAN
NC score	0.010404 (rank : 1102)	θ value	0.365318 (rank : 322)
Query Neighborhood Hits	458	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FIBP_HUMAN
NC score	0.008367 (rank : 1103)	θ value	6.88961 (rank : 429)
Query Neighborhood Hits	458	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O43427, Q6IBQ3, Q9HD65	Gene names	FIBP
Domain Architecture
Description	Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein).

ALMS1_MOUSE
NC score	0.006923 (rank : 1104)	θ value	6.88961 (rank : 422)
Query Neighborhood Hits	458	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

5NT1B_MOUSE
NC score	0.006808 (rank : 1105)	θ value	8.99809 (rank : 436)
Query Neighborhood Hits	458	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

APBP2_HUMAN
NC score	0.006384 (rank : 1106)	θ value	8.99809 (rank : 437)
Query Neighborhood Hits	458	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q92624, O95095, Q8WVC9	Gene names	APPBP2, KIAA0228, PAT1
Domain Architecture	No domain graphic available
Description	Amyloid protein-binding protein 2 (Amyloid beta precursor protein- binding protein 2) (APP-BP2) (Protein interacting with APP tail 1).

APBP2_MOUSE
NC score	0.006381 (rank : 1107)	θ value	8.99809 (rank : 438)
Query Neighborhood Hits	458	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DAX9, Q80U61	Gene names	Appbp2, Kiaa0228
Domain Architecture	No domain graphic available
Description	Amyloid protein-binding protein 2 (Amyloid beta precursor protein- binding protein 2) (APP-BP2).

FAM5A_HUMAN
NC score	0.006338 (rank : 1108)	θ value	6.88961 (rank : 427)
Query Neighborhood Hits	458	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O60477, Q6IPV6, Q6P1A0, Q8WU22	Gene names	FAM5A, DBC1, DBCCR1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein).

FAM5A_MOUSE
NC score	0.006093 (rank : 1109)	θ value	6.88961 (rank : 428)
Query Neighborhood Hits	458	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q920P3, Q80ZL2, Q812F0, Q8C1C9, Q920P4, Q9QXL0	Gene names	Fam5a, Brinp, Brinp1, Dbccr1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein homolog) (BMP/retinoic acid-inducible neural-specific protein 1).

MEF2A_HUMAN
NC score	0.004723 (rank : 1110)	θ value	5.27518 (rank : 416)
Query Neighborhood Hits	458	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

ABP1_HUMAN
NC score	0.004712 (rank : 1111)	θ value	5.27518 (rank : 409)
Query Neighborhood Hits	458	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P19801, Q16683, Q16684, Q56II4, Q6GU42	Gene names	ABP1, AOC1, DAO1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase) (Kidney amine oxidase) (KAO).

SIX4_HUMAN
NC score	0.003994 (rank : 1112)	θ value	1.06291 (rank : 355)
Query Neighborhood Hits	458	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIU6	Gene names	SIX4
Domain Architecture
Description	Homeobox protein SIX4 (Sine oculis homeobox homolog 4).

TMPS2_HUMAN
NC score	0.002992 (rank : 1113)	θ value	8.99809 (rank : 455)
Query Neighborhood Hits	458	Target Neighborhood Hits	252	Shared Neighborhood Hits	23
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

WN10B_HUMAN
NC score	0.002875 (rank : 1114)	θ value	4.03905 (rank : 407)
Query Neighborhood Hits	458	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	O00744, O00747, Q8WZ97	Gene names	WNT10B, WNT12
Domain Architecture
Description	Protein Wnt-10b precursor (Wnt-12).

WN10B_MOUSE
NC score	0.002865 (rank : 1115)	θ value	4.03905 (rank : 408)
Query Neighborhood Hits	458	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	P48614, P70702	Gene names	Wnt10b, Wnt-10b, Wnt10, Wnt12
Domain Architecture
Description	Protein Wnt-10b precursor (Wnt-12).

DIAP3_HUMAN
NC score	0.002807 (rank : 1116)	θ value	3.0926 (rank : 385)
Query Neighborhood Hits	458	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

MYH1_HUMAN
NC score	0.002583 (rank : 1117)	θ value	6.88961 (rank : 432)
Query Neighborhood Hits	458	Target Neighborhood Hits	1478	Shared Neighborhood Hits	32
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
NC score	0.002051 (rank : 1118)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	458	Target Neighborhood Hits	1461	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

RN167_HUMAN
NC score	0.001999 (rank : 1119)	θ value	5.27518 (rank : 421)
Query Neighborhood Hits	458	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

MYH2_HUMAN
NC score	0.001789 (rank : 1120)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	458	Target Neighborhood Hits	1491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

WDR1_MOUSE
NC score	-0.001960 (rank : 1121)	θ value	3.0926 (rank : 397)
Query Neighborhood Hits	458	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

WDR67_HUMAN
NC score	-0.005485 (rank : 1122)	θ value	8.99809 (rank : 458)
Query Neighborhood Hits	458	Target Neighborhood Hits	782	Shared Neighborhood Hits	10
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

ATBF1_HUMAN
NC score	-0.006465 (rank : 1123)	θ value	0.21417 (rank : 307)
Query Neighborhood Hits	458	Target Neighborhood Hits	1547	Shared Neighborhood Hits	17
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

TCF17_HUMAN
NC score	-0.011828 (rank : 1124)	θ value	8.99809 (rank : 454)
Query Neighborhood Hits	458	Target Neighborhood Hits	797	Shared Neighborhood Hits	18
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).