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Network neighborhood for query Sequence : TENN_HUMAN

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TENN_HUMAN
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TENN_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	453
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	0 (rank : 2)	NC score	0.981170 (rank : 2)
Query Neighborhood Hits	453	Target Neighborhood Hits	484	Shared Neighborhood Hits	392
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	0 (rank : 3)	NC score	0.956635 (rank : 3)
Query Neighborhood Hits	453	Target Neighborhood Hits	526	Shared Neighborhood Hits	392
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	0 (rank : 4)	NC score	0.954633 (rank : 4)
Query Neighborhood Hits	453	Target Neighborhood Hits	531	Shared Neighborhood Hits	391
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENA_HUMAN
θ value	4.87785e-155 (rank : 5)	NC score	0.871794 (rank : 6)
Query Neighborhood Hits	453	Target Neighborhood Hits	631	Shared Neighborhood Hits	410
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	6.82227e-149 (rank : 6)	NC score	0.878056 (rank : 5)
Query Neighborhood Hits	453	Target Neighborhood Hits	596	Shared Neighborhood Hits	402
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENX_HUMAN
θ value	2.35568e-133 (rank : 7)	NC score	0.868093 (rank : 7)
Query Neighborhood Hits	453	Target Neighborhood Hits	789	Shared Neighborhood Hits	410
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

FINC_HUMAN
θ value	1.07224e-85 (rank : 8)	NC score	0.606604 (rank : 41)
Query Neighborhood Hits	453	Target Neighborhood Hits	302	Shared Neighborhood Hits	160
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	5.50685e-82 (rank : 9)	NC score	0.600589 (rank : 42)
Query Neighborhood Hits	453	Target Neighborhood Hits	309	Shared Neighborhood Hits	158
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

COCA1_MOUSE
θ value	1.19377e-60 (rank : 10)	NC score	0.481979 (rank : 46)
Query Neighborhood Hits	453	Target Neighborhood Hits	467	Shared Neighborhood Hits	137
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_HUMAN
θ value	2.65945e-60 (rank : 11)	NC score	0.477050 (rank : 47)
Query Neighborhood Hits	453	Target Neighborhood Hits	458	Shared Neighborhood Hits	132
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

FCN1_MOUSE
θ value	1.19655e-52 (rank : 12)	NC score	0.678455 (rank : 33)
Query Neighborhood Hits	453	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN2_HUMAN
θ value	5.02714e-51 (rank : 13)	NC score	0.699770 (rank : 18)
Query Neighborhood Hits	453	Target Neighborhood Hits	122	Shared Neighborhood Hits	46
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

COEA1_HUMAN
θ value	1.91031e-50 (rank : 14)	NC score	0.427329 (rank : 56)
Query Neighborhood Hits	453	Target Neighborhood Hits	427	Shared Neighborhood Hits	115
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	2.75849e-49 (rank : 15)	NC score	0.445137 (rank : 52)
Query Neighborhood Hits	453	Target Neighborhood Hits	402	Shared Neighborhood Hits	107
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

FCN1_HUMAN
θ value	4.40402e-47 (rank : 16)	NC score	0.687493 (rank : 28)
Query Neighborhood Hits	453	Target Neighborhood Hits	147	Shared Neighborhood Hits	47
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

CO7A1_HUMAN
θ value	6.35935e-46 (rank : 17)	NC score	0.348877 (rank : 114)
Query Neighborhood Hits	453	Target Neighborhood Hits	807	Shared Neighborhood Hits	151
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MFAP4_HUMAN
θ value	2.41655e-45 (rank : 18)	NC score	0.722256 (rank : 9)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_MOUSE
θ value	2.41655e-45 (rank : 19)	NC score	0.722409 (rank : 8)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

FCN3_HUMAN
θ value	5.95217e-44 (rank : 20)	NC score	0.710436 (rank : 12)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	48
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

ANGL7_MOUSE
θ value	2.95404e-43 (rank : 21)	NC score	0.710738 (rank : 11)
Query Neighborhood Hits	453	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

ANGL1_HUMAN
θ value	1.91475e-42 (rank : 22)	NC score	0.695013 (rank : 22)
Query Neighborhood Hits	453	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	O95841, Q5T5Z5	Gene names	ANGPTL1, ANG3, ANGPT3, ARP1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1) (Angiopoietin-3) (ANG-3).

ANGL1_MOUSE
θ value	4.2656e-42 (rank : 23)	NC score	0.694875 (rank : 24)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

ANGL7_HUMAN
θ value	1.62093e-41 (rank : 24)	NC score	0.710362 (rank : 13)
Query Neighborhood Hits	453	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

ANGL2_MOUSE
θ value	8.04462e-41 (rank : 25)	NC score	0.694605 (rank : 25)
Query Neighborhood Hits	453	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL2_HUMAN
θ value	1.05066e-40 (rank : 26)	NC score	0.694334 (rank : 26)
Query Neighborhood Hits	453	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGP4_HUMAN
θ value	5.21438e-40 (rank : 27)	NC score	0.683558 (rank : 32)
Query Neighborhood Hits	453	Target Neighborhood Hits	187	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

FIBB_HUMAN
θ value	2.19075e-38 (rank : 28)	NC score	0.694887 (rank : 23)
Query Neighborhood Hits	453	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

ANGP4_MOUSE
θ value	3.73686e-38 (rank : 29)	NC score	0.675722 (rank : 34)
Query Neighborhood Hits	453	Target Neighborhood Hits	220	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

FIBA_HUMAN
θ value	6.37413e-38 (rank : 30)	NC score	0.697420 (rank : 20)
Query Neighborhood Hits	453	Target Neighborhood Hits	132	Shared Neighborhood Hits	48
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

ANGL6_HUMAN
θ value	1.08726e-37 (rank : 31)	NC score	0.702647 (rank : 16)
Query Neighborhood Hits	453	Target Neighborhood Hits	70	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

ANGL6_MOUSE
θ value	1.08726e-37 (rank : 32)	NC score	0.705340 (rank : 14)
Query Neighborhood Hits	453	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

FIBB_MOUSE
θ value	1.42001e-37 (rank : 33)	NC score	0.695481 (rank : 21)
Query Neighborhood Hits	453	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

FGL1_HUMAN
θ value	1.85459e-37 (rank : 34)	NC score	0.711082 (rank : 10)
Query Neighborhood Hits	453	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	Q08830, Q4PJH9, Q96KW6, Q96QM6	Gene names	FGL1, HFREP1
Domain Architecture
Description	Fibrinogen-like protein 1 precursor (Hepatocyte-derived fibrinogen- related protein 1) (HFREP-1) (Hepassocin) (HP-041).

FGL2_MOUSE
θ value	3.16345e-37 (rank : 35)	NC score	0.701019 (rank : 17)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	42
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

PTPRB_HUMAN
θ value	1.01765e-35 (rank : 36)	NC score	0.344452 (rank : 117)
Query Neighborhood Hits	453	Target Neighborhood Hits	242	Shared Neighborhood Hits	85
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

ANGP1_HUMAN
θ value	1.73584e-35 (rank : 37)	NC score	0.668611 (rank : 35)
Query Neighborhood Hits	453	Target Neighborhood Hits	254	Shared Neighborhood Hits	43
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

FGL2_HUMAN
θ value	1.73584e-35 (rank : 38)	NC score	0.699091 (rank : 19)
Query Neighborhood Hits	453	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

ANGP1_MOUSE
θ value	2.96089e-35 (rank : 39)	NC score	0.668188 (rank : 36)
Query Neighborhood Hits	453	Target Neighborhood Hits	252	Shared Neighborhood Hits	42
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP2_MOUSE
θ value	6.59618e-35 (rank : 40)	NC score	0.642452 (rank : 40)
Query Neighborhood Hits	453	Target Neighborhood Hits	397	Shared Neighborhood Hits	46
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGP2_HUMAN
θ value	2.50655e-34 (rank : 41)	NC score	0.645882 (rank : 39)
Query Neighborhood Hits	453	Target Neighborhood Hits	400	Shared Neighborhood Hits	47
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

FIBG_HUMAN
θ value	2.34606e-32 (rank : 42)	NC score	0.686000 (rank : 31)
Query Neighborhood Hits	453	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	P02679, P04469, P04470, Q96A14, Q96KJ3	Gene names	FGG
Domain Architecture
Description	Fibrinogen gamma chain precursor.

FIBG_MOUSE
θ value	1.98606e-31 (rank : 43)	NC score	0.688136 (rank : 27)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VCM7, Q8WUR3, Q91ZP0	Gene names	Fgg
Domain Architecture	No domain graphic available
Description	Fibrinogen gamma chain precursor.

ANGL5_HUMAN
θ value	1.6813e-30 (rank : 44)	NC score	0.703714 (rank : 15)
Query Neighborhood Hits	453	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

ANGL4_MOUSE
θ value	9.2256e-29 (rank : 45)	NC score	0.687297 (rank : 30)
Query Neighborhood Hits	453	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

PTPRV_MOUSE
θ value	1.2049e-28 (rank : 46)	NC score	0.296577 (rank : 168)
Query Neighborhood Hits	453	Target Neighborhood Hits	179	Shared Neighborhood Hits	73
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

ANGL4_HUMAN
θ value	3.50572e-28 (rank : 47)	NC score	0.687447 (rank : 29)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

PTPRD_HUMAN
θ value	1.92365e-26 (rank : 48)	NC score	0.339630 (rank : 120)
Query Neighborhood Hits	453	Target Neighborhood Hits	485	Shared Neighborhood Hits	143
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

COKA1_HUMAN
θ value	1.24688e-25 (rank : 49)	NC score	0.409205 (rank : 75)
Query Neighborhood Hits	453	Target Neighborhood Hits	403	Shared Neighborhood Hits	109
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

PTPRF_HUMAN
θ value	8.93572e-24 (rank : 50)	NC score	0.326476 (rank : 136)
Query Neighborhood Hits	453	Target Neighborhood Hits	489	Shared Neighborhood Hits	141
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

ANGL3_MOUSE
θ value	1.5242e-23 (rank : 51)	NC score	0.648736 (rank : 37)
Query Neighborhood Hits	453	Target Neighborhood Hits	306	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

PTPRD_MOUSE
θ value	1.99067e-23 (rank : 52)	NC score	0.336956 (rank : 123)
Query Neighborhood Hits	453	Target Neighborhood Hits	491	Shared Neighborhood Hits	141
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

TITIN_HUMAN
θ value	1.5773e-20 (rank : 53)	NC score	0.181253 (rank : 363)
Query Neighborhood Hits	453	Target Neighborhood Hits	2923	Shared Neighborhood Hits	178
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ANGL3_HUMAN
θ value	2.69047e-20 (rank : 54)	NC score	0.646791 (rank : 38)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

PTPRS_HUMAN
θ value	4.74913e-17 (rank : 55)	NC score	0.321323 (rank : 139)
Query Neighborhood Hits	453	Target Neighborhood Hits	472	Shared Neighborhood Hits	140
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

ITB5_MOUSE
θ value	4.02038e-16 (rank : 56)	NC score	0.422848 (rank : 59)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	216
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

TIE2_HUMAN
θ value	5.25075e-16 (rank : 57)	NC score	0.201824 (rank : 328)
Query Neighborhood Hits	453	Target Neighborhood Hits	1192	Shared Neighborhood Hits	294
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

ITB5_HUMAN
θ value	5.8054e-15 (rank : 58)	NC score	0.417276 (rank : 61)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	211
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

WIF1_HUMAN
θ value	7.58209e-15 (rank : 59)	NC score	0.490254 (rank : 44)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	247
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

PTPRJ_HUMAN
θ value	2.88119e-14 (rank : 60)	NC score	0.264830 (rank : 205)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	92
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

NEO1_HUMAN
θ value	6.41864e-14 (rank : 61)	NC score	0.333788 (rank : 127)
Query Neighborhood Hits	453	Target Neighborhood Hits	530	Shared Neighborhood Hits	140
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

WIF1_MOUSE
θ value	6.41864e-14 (rank : 62)	NC score	0.486980 (rank : 45)
Query Neighborhood Hits	453	Target Neighborhood Hits	393	Shared Neighborhood Hits	244
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ITB7_HUMAN
θ value	1.86753e-13 (rank : 63)	NC score	0.416501 (rank : 63)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	197
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	2.43908e-13 (rank : 64)	NC score	0.412977 (rank : 70)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	200
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

NEO1_MOUSE
θ value	3.18553e-13 (rank : 65)	NC score	0.335975 (rank : 124)
Query Neighborhood Hits	453	Target Neighborhood Hits	523	Shared Neighborhood Hits	140
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

MEGF6_HUMAN
θ value	2.0648e-12 (rank : 66)	NC score	0.395704 (rank : 89)
Query Neighborhood Hits	453	Target Neighborhood Hits	671	Shared Neighborhood Hits	281
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TIE2_MOUSE
θ value	2.0648e-12 (rank : 67)	NC score	0.197494 (rank : 341)
Query Neighborhood Hits	453	Target Neighborhood Hits	1204	Shared Neighborhood Hits	298
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TIE1_MOUSE
θ value	3.52202e-12 (rank : 68)	NC score	0.208815 (rank : 311)
Query Neighborhood Hits	453	Target Neighborhood Hits	1266	Shared Neighborhood Hits	313
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

FBN3_HUMAN
θ value	6.00763e-12 (rank : 69)	NC score	0.331074 (rank : 132)
Query Neighborhood Hits	453	Target Neighborhood Hits	543	Shared Neighborhood Hits	264
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN2_MOUSE
θ value	7.84624e-12 (rank : 70)	NC score	0.332370 (rank : 130)
Query Neighborhood Hits	453	Target Neighborhood Hits	549	Shared Neighborhood Hits	269
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

ITB6_HUMAN
θ value	7.84624e-12 (rank : 71)	NC score	0.424256 (rank : 58)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	210
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

FBN1_MOUSE
θ value	1.02475e-11 (rank : 72)	NC score	0.331858 (rank : 131)
Query Neighborhood Hits	453	Target Neighborhood Hits	563	Shared Neighborhood Hits	275
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

ITB1_HUMAN
θ value	1.02475e-11 (rank : 73)	NC score	0.403695 (rank : 77)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	191
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

NAGPA_MOUSE
θ value	1.02475e-11 (rank : 74)	NC score	0.467519 (rank : 50)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TIE1_HUMAN
θ value	1.02475e-11 (rank : 75)	NC score	0.208483 (rank : 314)
Query Neighborhood Hits	453	Target Neighborhood Hits	1241	Shared Neighborhood Hits	315
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

FBN2_HUMAN
θ value	1.33837e-11 (rank : 76)	NC score	0.335257 (rank : 125)
Query Neighborhood Hits	453	Target Neighborhood Hits	560	Shared Neighborhood Hits	273
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_HUMAN
θ value	1.74796e-11 (rank : 77)	NC score	0.329966 (rank : 135)
Query Neighborhood Hits	453	Target Neighborhood Hits	557	Shared Neighborhood Hits	274
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

ITB3_HUMAN
θ value	2.98157e-11 (rank : 78)	NC score	0.420665 (rank : 60)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	216
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

USH2A_MOUSE
θ value	2.98157e-11 (rank : 79)	NC score	0.468338 (rank : 49)
Query Neighborhood Hits	453	Target Neighborhood Hits	626	Shared Neighborhood Hits	319
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ITB6_MOUSE
θ value	3.89403e-11 (rank : 80)	NC score	0.424293 (rank : 57)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	214
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB8_HUMAN
θ value	3.89403e-11 (rank : 81)	NC score	0.403571 (rank : 78)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	189
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

NOTC4_HUMAN
θ value	3.89403e-11 (rank : 82)	NC score	0.345875 (rank : 116)
Query Neighborhood Hits	453	Target Neighborhood Hits	905	Shared Neighborhood Hits	277
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DCC_MOUSE
θ value	6.64225e-11 (rank : 83)	NC score	0.309236 (rank : 149)
Query Neighborhood Hits	453	Target Neighborhood Hits	896	Shared Neighborhood Hits	146
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DCC_HUMAN
θ value	8.67504e-11 (rank : 84)	NC score	0.316538 (rank : 141)
Query Neighborhood Hits	453	Target Neighborhood Hits	583	Shared Neighborhood Hits	141
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

ITB3_MOUSE
θ value	1.9326e-10 (rank : 85)	NC score	0.417133 (rank : 62)
Query Neighborhood Hits	453	Target Neighborhood Hits	319	Shared Neighborhood Hits	207
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

SDK2_MOUSE
θ value	1.9326e-10 (rank : 86)	NC score	0.342928 (rank : 118)
Query Neighborhood Hits	453	Target Neighborhood Hits	480	Shared Neighborhood Hits	143
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

FNDC3_MOUSE
θ value	3.29651e-10 (rank : 87)	NC score	0.402380 (rank : 82)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	131
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

STAB1_HUMAN
θ value	3.29651e-10 (rank : 88)	NC score	0.373824 (rank : 98)
Query Neighborhood Hits	453	Target Neighborhood Hits	546	Shared Neighborhood Hits	270
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ITB1_MOUSE
θ value	5.62301e-10 (rank : 89)	NC score	0.403521 (rank : 79)
Query Neighborhood Hits	453	Target Neighborhood Hits	283	Shared Neighborhood Hits	186
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

LRP1B_MOUSE
θ value	5.62301e-10 (rank : 90)	NC score	0.309221 (rank : 150)
Query Neighborhood Hits	453	Target Neighborhood Hits	606	Shared Neighborhood Hits	276
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SREC_HUMAN
θ value	5.62301e-10 (rank : 91)	NC score	0.429463 (rank : 55)
Query Neighborhood Hits	453	Target Neighborhood Hits	645	Shared Neighborhood Hits	271
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ITB4_HUMAN
θ value	7.34386e-10 (rank : 92)	NC score	0.527783 (rank : 43)
Query Neighborhood Hits	453	Target Neighborhood Hits	458	Shared Neighborhood Hits	300
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

NAGPA_HUMAN
θ value	9.59137e-10 (rank : 93)	NC score	0.472215 (rank : 48)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	208
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NOTC1_HUMAN
θ value	1.63604e-09 (rank : 94)	NC score	0.355335 (rank : 109)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	269
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

USH2A_HUMAN
θ value	2.13673e-09 (rank : 95)	NC score	0.461393 (rank : 51)
Query Neighborhood Hits	453	Target Neighborhood Hits	600	Shared Neighborhood Hits	315
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ITB2_HUMAN
θ value	2.79066e-09 (rank : 96)	NC score	0.413392 (rank : 69)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	197
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
θ value	2.79066e-09 (rank : 97)	NC score	0.416391 (rank : 64)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	224
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

STAB1_MOUSE
θ value	2.79066e-09 (rank : 98)	NC score	0.377194 (rank : 96)
Query Neighborhood Hits	453	Target Neighborhood Hits	566	Shared Neighborhood Hits	272
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

NOTC3_MOUSE
θ value	3.64472e-09 (rank : 99)	NC score	0.351866 (rank : 111)
Query Neighborhood Hits	453	Target Neighborhood Hits	975	Shared Neighborhood Hits	275
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PTPRJ_MOUSE
θ value	4.76016e-09 (rank : 100)	NC score	0.255547 (rank : 218)
Query Neighborhood Hits	453	Target Neighborhood Hits	188	Shared Neighborhood Hits	86
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

SDK2_HUMAN
θ value	4.76016e-09 (rank : 101)	NC score	0.337193 (rank : 122)
Query Neighborhood Hits	453	Target Neighborhood Hits	495	Shared Neighborhood Hits	141
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

EGFL9_HUMAN
θ value	6.21693e-09 (rank : 102)	NC score	0.413826 (rank : 68)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	238
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

LRP1B_HUMAN
θ value	1.06045e-08 (rank : 103)	NC score	0.308704 (rank : 152)
Query Neighborhood Hits	453	Target Neighborhood Hits	602	Shared Neighborhood Hits	276
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

DNER_HUMAN
θ value	1.38499e-08 (rank : 104)	NC score	0.393399 (rank : 90)
Query Neighborhood Hits	453	Target Neighborhood Hits	460	Shared Neighborhood Hits	239
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

NOTC4_MOUSE
θ value	1.80886e-08 (rank : 105)	NC score	0.342076 (rank : 119)
Query Neighborhood Hits	453	Target Neighborhood Hits	872	Shared Neighborhood Hits	273
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SDK1_HUMAN
θ value	1.80886e-08 (rank : 106)	NC score	0.330467 (rank : 133)
Query Neighborhood Hits	453	Target Neighborhood Hits	511	Shared Neighborhood Hits	141
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

DNER_MOUSE
θ value	3.08544e-08 (rank : 107)	NC score	0.392967 (rank : 91)
Query Neighborhood Hits	453	Target Neighborhood Hits	413	Shared Neighborhood Hits	236
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

SREC2_HUMAN
θ value	3.08544e-08 (rank : 108)	NC score	0.441826 (rank : 53)
Query Neighborhood Hits	453	Target Neighborhood Hits	645	Shared Neighborhood Hits	263
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	3.08544e-08 (rank : 109)	NC score	0.441136 (rank : 54)
Query Neighborhood Hits	453	Target Neighborhood Hits	605	Shared Neighborhood Hits	255
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LRP1_HUMAN
θ value	4.0297e-08 (rank : 110)	NC score	0.308988 (rank : 151)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	278
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

EGFL9_MOUSE
θ value	6.87365e-08 (rank : 111)	NC score	0.411400 (rank : 71)
Query Neighborhood Hits	453	Target Neighborhood Hits	379	Shared Neighborhood Hits	241
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

NOTC3_HUMAN
θ value	6.87365e-08 (rank : 112)	NC score	0.351912 (rank : 110)
Query Neighborhood Hits	453	Target Neighborhood Hits	1062	Shared Neighborhood Hits	277
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

STAB2_HUMAN
θ value	6.87365e-08 (rank : 113)	NC score	0.375849 (rank : 97)
Query Neighborhood Hits	453	Target Neighborhood Hits	534	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

DLL3_MOUSE
θ value	8.97725e-08 (rank : 114)	NC score	0.396320 (rank : 88)
Query Neighborhood Hits	453	Target Neighborhood Hits	399	Shared Neighborhood Hits	233
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

NOTC1_MOUSE
θ value	8.97725e-08 (rank : 115)	NC score	0.360155 (rank : 106)
Query Neighborhood Hits	453	Target Neighborhood Hits	916	Shared Neighborhood Hits	268
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CNTN3_MOUSE
θ value	1.17247e-07 (rank : 116)	NC score	0.257819 (rank : 215)
Query Neighborhood Hits	453	Target Neighborhood Hits	447	Shared Neighborhood Hits	135
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN5_HUMAN
θ value	1.17247e-07 (rank : 117)	NC score	0.248375 (rank : 229)
Query Neighborhood Hits	453	Target Neighborhood Hits	446	Shared Neighborhood Hits	132
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

DLK_HUMAN
θ value	1.17247e-07 (rank : 118)	NC score	0.416306 (rank : 65)
Query Neighborhood Hits	453	Target Neighborhood Hits	401	Shared Neighborhood Hits	243
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL3_HUMAN
θ value	2.61198e-07 (rank : 119)	NC score	0.400233 (rank : 85)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	236
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

JAG2_HUMAN
θ value	2.61198e-07 (rank : 120)	NC score	0.396479 (rank : 87)
Query Neighborhood Hits	453	Target Neighborhood Hits	491	Shared Neighborhood Hits	256
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG1_HUMAN
θ value	3.41135e-07 (rank : 121)	NC score	0.402743 (rank : 81)
Query Neighborhood Hits	453	Target Neighborhood Hits	514	Shared Neighborhood Hits	261
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG2_MOUSE
θ value	3.41135e-07 (rank : 122)	NC score	0.397278 (rank : 86)
Query Neighborhood Hits	453	Target Neighborhood Hits	504	Shared Neighborhood Hits	259
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NOTC2_HUMAN
θ value	3.41135e-07 (rank : 123)	NC score	0.350177 (rank : 113)
Query Neighborhood Hits	453	Target Neighborhood Hits	1113	Shared Neighborhood Hits	281
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	3.41135e-07 (rank : 124)	NC score	0.350554 (rank : 112)
Query Neighborhood Hits	453	Target Neighborhood Hits	1069	Shared Neighborhood Hits	275
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SDK1_MOUSE
θ value	3.41135e-07 (rank : 125)	NC score	0.330109 (rank : 134)
Query Neighborhood Hits	453	Target Neighborhood Hits	495	Shared Neighborhood Hits	142
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

CNTN5_MOUSE
θ value	4.45536e-07 (rank : 126)	NC score	0.252150 (rank : 221)
Query Neighborhood Hits	453	Target Neighborhood Hits	434	Shared Neighborhood Hits	128
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

ROBO2_MOUSE
θ value	4.45536e-07 (rank : 127)	NC score	0.235531 (rank : 255)
Query Neighborhood Hits	453	Target Neighborhood Hits	504	Shared Neighborhood Hits	131
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

LAMA5_HUMAN
θ value	5.81887e-07 (rank : 128)	NC score	0.333470 (rank : 129)
Query Neighborhood Hits	453	Target Neighborhood Hits	976	Shared Neighborhood Hits	266
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

STAB2_MOUSE
θ value	5.81887e-07 (rank : 129)	NC score	0.373023 (rank : 99)
Query Neighborhood Hits	453	Target Neighborhood Hits	528	Shared Neighborhood Hits	271
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

DLK_MOUSE
θ value	9.92553e-07 (rank : 130)	NC score	0.409742 (rank : 73)
Query Neighborhood Hits	453	Target Neighborhood Hits	374	Shared Neighborhood Hits	233
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

JAG1_MOUSE
θ value	2.88788e-06 (rank : 131)	NC score	0.402783 (rank : 80)
Query Neighborhood Hits	453	Target Neighborhood Hits	518	Shared Neighborhood Hits	263
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DLL1_HUMAN
θ value	3.77169e-06 (rank : 132)	NC score	0.391881 (rank : 92)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	254
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	3.77169e-06 (rank : 133)	NC score	0.391789 (rank : 93)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	259
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

NRCAM_HUMAN
θ value	3.77169e-06 (rank : 134)	NC score	0.299377 (rank : 167)
Query Neighborhood Hits	453	Target Neighborhood Hits	439	Shared Neighborhood Hits	131
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

SLIT1_HUMAN
θ value	3.77169e-06 (rank : 135)	NC score	0.277820 (rank : 190)
Query Neighborhood Hits	453	Target Neighborhood Hits	700	Shared Neighborhood Hits	244
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

CELR1_MOUSE
θ value	4.92598e-06 (rank : 136)	NC score	0.175195 (rank : 372)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	218
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CRUM2_HUMAN
θ value	4.92598e-06 (rank : 137)	NC score	0.367212 (rank : 104)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	243
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CRUM1_MOUSE
θ value	6.43352e-06 (rank : 138)	NC score	0.371629 (rank : 101)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	238
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DSCL1_HUMAN
θ value	6.43352e-06 (rank : 139)	NC score	0.290741 (rank : 175)
Query Neighborhood Hits	453	Target Neighborhood Hits	589	Shared Neighborhood Hits	137
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

ROBO2_HUMAN
θ value	6.43352e-06 (rank : 140)	NC score	0.233384 (rank : 261)
Query Neighborhood Hits	453	Target Neighborhood Hits	479	Shared Neighborhood Hits	130
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SLIT1_MOUSE
θ value	6.43352e-06 (rank : 141)	NC score	0.276992 (rank : 193)
Query Neighborhood Hits	453	Target Neighborhood Hits	715	Shared Neighborhood Hits	247
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ADAM8_HUMAN
θ value	8.40245e-06 (rank : 142)	NC score	0.145950 (rank : 418)
Query Neighborhood Hits	453	Target Neighborhood Hits	327	Shared Neighborhood Hits	176
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

DLL4_HUMAN
θ value	8.40245e-06 (rank : 143)	NC score	0.400386 (rank : 84)
Query Neighborhood Hits	453	Target Neighborhood Hits	435	Shared Neighborhood Hits	243
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

CNTN3_HUMAN
θ value	1.09739e-05 (rank : 144)	NC score	0.255613 (rank : 217)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	138
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

LAMA5_MOUSE
θ value	1.09739e-05 (rank : 145)	NC score	0.338814 (rank : 121)
Query Neighborhood Hits	453	Target Neighborhood Hits	828	Shared Neighborhood Hits	262
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF8_HUMAN
θ value	1.09739e-05 (rank : 146)	NC score	0.333516 (rank : 128)
Query Neighborhood Hits	453	Target Neighborhood Hits	528	Shared Neighborhood Hits	244
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

HABP2_MOUSE
θ value	1.43324e-05 (rank : 147)	NC score	0.163969 (rank : 390)
Query Neighborhood Hits	453	Target Neighborhood Hits	445	Shared Neighborhood Hits	189
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LAMA1_MOUSE
θ value	1.43324e-05 (rank : 148)	NC score	0.313505 (rank : 144)
Query Neighborhood Hits	453	Target Neighborhood Hits	838	Shared Neighborhood Hits	256
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MEGF8_MOUSE
θ value	1.87187e-05 (rank : 149)	NC score	0.326128 (rank : 137)
Query Neighborhood Hits	453	Target Neighborhood Hits	520	Shared Neighborhood Hits	241
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SLIT2_HUMAN
θ value	1.87187e-05 (rank : 150)	NC score	0.271595 (rank : 198)
Query Neighborhood Hits	453	Target Neighborhood Hits	708	Shared Neighborhood Hits	248
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	1.87187e-05 (rank : 151)	NC score	0.266192 (rank : 202)
Query Neighborhood Hits	453	Target Neighborhood Hits	684	Shared Neighborhood Hits	239
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CNTN2_MOUSE
θ value	2.44474e-05 (rank : 152)	NC score	0.250014 (rank : 227)
Query Neighborhood Hits	453	Target Neighborhood Hits	450	Shared Neighborhood Hits	130
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

ROBO3_HUMAN
θ value	2.44474e-05 (rank : 153)	NC score	0.233542 (rank : 259)
Query Neighborhood Hits	453	Target Neighborhood Hits	570	Shared Neighborhood Hits	137
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

LTBP2_HUMAN
θ value	3.19293e-05 (rank : 154)	NC score	0.313604 (rank : 143)
Query Neighborhood Hits	453	Target Neighborhood Hits	552	Shared Neighborhood Hits	265
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NRCAM_MOUSE
θ value	3.19293e-05 (rank : 155)	NC score	0.286444 (rank : 183)
Query Neighborhood Hits	453	Target Neighborhood Hits	432	Shared Neighborhood Hits	132
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

CELR1_HUMAN
θ value	4.1701e-05 (rank : 156)	NC score	0.177582 (rank : 368)
Query Neighborhood Hits	453	Target Neighborhood Hits	613	Shared Neighborhood Hits	206
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

L1CAM_HUMAN
θ value	4.1701e-05 (rank : 157)	NC score	0.273884 (rank : 196)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	133
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LAMA1_HUMAN
θ value	4.1701e-05 (rank : 158)	NC score	0.304941 (rank : 160)
Query Neighborhood Hits	453	Target Neighborhood Hits	804	Shared Neighborhood Hits	246
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC1_MOUSE
θ value	5.44631e-05 (rank : 159)	NC score	0.290445 (rank : 176)
Query Neighborhood Hits	453	Target Neighborhood Hits	856	Shared Neighborhood Hits	232
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

CNTN2_HUMAN
θ value	7.1131e-05 (rank : 160)	NC score	0.252569 (rank : 220)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	131
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

LAMC1_HUMAN
θ value	7.1131e-05 (rank : 161)	NC score	0.277262 (rank : 191)
Query Neighborhood Hits	453	Target Neighborhood Hits	922	Shared Neighborhood Hits	236
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ATRN_MOUSE
θ value	0.000121331 (rank : 162)	NC score	0.276632 (rank : 194)
Query Neighborhood Hits	453	Target Neighborhood Hits	519	Shared Neighborhood Hits	211
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CELR3_MOUSE
θ value	0.000121331 (rank : 163)	NC score	0.177336 (rank : 369)
Query Neighborhood Hits	453	Target Neighborhood Hits	687	Shared Neighborhood Hits	235
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

DLL4_MOUSE
θ value	0.000121331 (rank : 164)	NC score	0.400458 (rank : 83)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	249
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

HABP2_HUMAN
θ value	0.000121331 (rank : 165)	NC score	0.164945 (rank : 388)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	187
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

RELN_MOUSE
θ value	0.000121331 (rank : 166)	NC score	0.239029 (rank : 249)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	159
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

CRUM1_HUMAN
θ value	0.000158464 (rank : 167)	NC score	0.372264 (rank : 100)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	244
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FNDC3_HUMAN
θ value	0.000158464 (rank : 168)	NC score	0.388050 (rank : 94)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

RELN_HUMAN
θ value	0.000158464 (rank : 169)	NC score	0.234446 (rank : 256)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	158
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

CELR3_HUMAN
θ value	0.00020696 (rank : 170)	NC score	0.178091 (rank : 366)
Query Neighborhood Hits	453	Target Neighborhood Hits	680	Shared Neighborhood Hits	236
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

L1CAM_MOUSE
θ value	0.00020696 (rank : 171)	NC score	0.269622 (rank : 200)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	135
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

NFASC_MOUSE
θ value	0.00020696 (rank : 172)	NC score	0.247934 (rank : 231)
Query Neighborhood Hits	453	Target Neighborhood Hits	475	Shared Neighborhood Hits	129
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

CNTN1_MOUSE
θ value	0.000270298 (rank : 173)	NC score	0.240351 (rank : 245)
Query Neighborhood Hits	453	Target Neighborhood Hits	422	Shared Neighborhood Hits	122
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

KRA58_HUMAN
θ value	0.000270298 (rank : 174)	NC score	0.415411 (rank : 66)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	183
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ATRN_HUMAN
θ value	0.00035302 (rank : 175)	NC score	0.277085 (rank : 192)
Query Neighborhood Hits	453	Target Neighborhood Hits	525	Shared Neighborhood Hits	217
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

EPHA6_HUMAN
θ value	0.00035302 (rank : 176)	NC score	0.080462 (rank : 689)
Query Neighborhood Hits	453	Target Neighborhood Hits	959	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

HHIP_HUMAN
θ value	0.00035302 (rank : 177)	NC score	0.366367 (rank : 105)
Query Neighborhood Hits	453	Target Neighborhood Hits	249	Shared Neighborhood Hits	196
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

CSF3R_HUMAN
θ value	0.000461057 (rank : 178)	NC score	0.212330 (rank : 304)
Query Neighborhood Hits	453	Target Neighborhood Hits	140	Shared Neighborhood Hits	87
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

SORL_HUMAN
θ value	0.000461057 (rank : 179)	NC score	0.287393 (rank : 180)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	262
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	0.000461057 (rank : 180)	NC score	0.295191 (rank : 170)
Query Neighborhood Hits	453	Target Neighborhood Hits	439	Shared Neighborhood Hits	265
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LRP4_HUMAN
θ value	0.000602161 (rank : 181)	NC score	0.211713 (rank : 306)
Query Neighborhood Hits	453	Target Neighborhood Hits	355	Shared Neighborhood Hits	186
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	0.000602161 (rank : 182)	NC score	0.213391 (rank : 301)
Query Neighborhood Hits	453	Target Neighborhood Hits	351	Shared Neighborhood Hits	188
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

ROBO1_HUMAN
θ value	0.000602161 (rank : 183)	NC score	0.218372 (rank : 292)
Query Neighborhood Hits	453	Target Neighborhood Hits	529	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

SLIT3_HUMAN
θ value	0.000602161 (rank : 184)	NC score	0.255746 (rank : 216)
Query Neighborhood Hits	453	Target Neighborhood Hits	682	Shared Neighborhood Hits	234
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

CNTN1_HUMAN
θ value	0.000786445 (rank : 185)	NC score	0.241739 (rank : 241)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	121
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

HHIP_MOUSE
θ value	0.000786445 (rank : 186)	NC score	0.357528 (rank : 108)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	176
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LAMA2_MOUSE
θ value	0.00102713 (rank : 187)	NC score	0.279207 (rank : 188)
Query Neighborhood Hits	453	Target Neighborhood Hits	1198	Shared Neighborhood Hits	241
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB3_MOUSE
θ value	0.00102713 (rank : 188)	NC score	0.308153 (rank : 153)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	192
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

SLIT3_MOUSE
θ value	0.00102713 (rank : 189)	NC score	0.260030 (rank : 214)
Query Neighborhood Hits	453	Target Neighborhood Hits	700	Shared Neighborhood Hits	243
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ADA15_HUMAN
θ value	0.00134147 (rank : 190)	NC score	0.136728 (rank : 430)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	174
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

EPHA6_MOUSE
θ value	0.00134147 (rank : 191)	NC score	0.073986 (rank : 737)
Query Neighborhood Hits	453	Target Neighborhood Hits	946	Shared Neighborhood Hits	129
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

LAMB2_MOUSE
θ value	0.00134147 (rank : 192)	NC score	0.311871 (rank : 146)
Query Neighborhood Hits	453	Target Neighborhood Hits	722	Shared Neighborhood Hits	228
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LTBP2_MOUSE
θ value	0.00134147 (rank : 193)	NC score	0.310449 (rank : 147)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	255
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

ROBO3_MOUSE
θ value	0.00134147 (rank : 194)	NC score	0.220479 (rank : 285)
Query Neighborhood Hits	453	Target Neighborhood Hits	524	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

LAMA2_HUMAN
θ value	0.00175202 (rank : 195)	NC score	0.290087 (rank : 177)
Query Neighborhood Hits	453	Target Neighborhood Hits	1092	Shared Neighborhood Hits	243
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ADA15_MOUSE
θ value	0.00228821 (rank : 196)	NC score	0.140652 (rank : 424)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	177
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

LAMB2_HUMAN
θ value	0.00228821 (rank : 197)	NC score	0.312453 (rank : 145)
Query Neighborhood Hits	453	Target Neighborhood Hits	692	Shared Neighborhood Hits	230
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

BOC_HUMAN
θ value	0.00298849 (rank : 198)	NC score	0.215637 (rank : 297)
Query Neighborhood Hits	453	Target Neighborhood Hits	543	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

ROBO1_MOUSE
θ value	0.00298849 (rank : 199)	NC score	0.226465 (rank : 273)
Query Neighborhood Hits	453	Target Neighborhood Hits	559	Shared Neighborhood Hits	129
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

CRLF1_MOUSE
θ value	0.00390308 (rank : 200)	NC score	0.112014 (rank : 496)
Query Neighborhood Hits	453	Target Neighborhood Hits	116	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

EPHA5_MOUSE
θ value	0.00390308 (rank : 201)	NC score	0.064658 (rank : 803)
Query Neighborhood Hits	453	Target Neighborhood Hits	950	Shared Neighborhood Hits	118
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

KRA57_HUMAN
θ value	0.00390308 (rank : 202)	NC score	0.404022 (rank : 76)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	163
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

MYPC2_MOUSE
θ value	0.00390308 (rank : 203)	NC score	0.214899 (rank : 298)
Query Neighborhood Hits	453	Target Neighborhood Hits	297	Shared Neighborhood Hits	100
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

CRLF1_HUMAN
θ value	0.00509761 (rank : 204)	NC score	0.111302 (rank : 499)
Query Neighborhood Hits	453	Target Neighborhood Hits	122	Shared Neighborhood Hits	67
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

LAMC3_MOUSE
θ value	0.00509761 (rank : 205)	NC score	0.305440 (rank : 158)
Query Neighborhood Hits	453	Target Neighborhood Hits	624	Shared Neighborhood Hits	234
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

NET2_MOUSE
θ value	0.00509761 (rank : 206)	NC score	0.205155 (rank : 321)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	146
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

PGBM_HUMAN
θ value	0.00509761 (rank : 207)	NC score	0.302670 (rank : 163)
Query Neighborhood Hits	453	Target Neighborhood Hits	1113	Shared Neighborhood Hits	318
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ADA32_MOUSE
θ value	0.00665767 (rank : 208)	NC score	0.117823 (rank : 481)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	140
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADAM8_MOUSE
θ value	0.00665767 (rank : 209)	NC score	0.143139 (rank : 422)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	169
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

DSCAM_HUMAN
θ value	0.00665767 (rank : 210)	NC score	0.282154 (rank : 185)
Query Neighborhood Hits	453	Target Neighborhood Hits	524	Shared Neighborhood Hits	135
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

ADA28_HUMAN
θ value	0.00869519 (rank : 211)	NC score	0.123193 (rank : 462)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

LAMB1_MOUSE
θ value	0.00869519 (rank : 212)	NC score	0.299913 (rank : 166)
Query Neighborhood Hits	453	Target Neighborhood Hits	919	Shared Neighborhood Hits	228
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

PTPRT_HUMAN
θ value	0.00869519 (rank : 213)	NC score	0.207931 (rank : 316)
Query Neighborhood Hits	453	Target Neighborhood Hits	217	Shared Neighborhood Hits	107
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	0.00869519 (rank : 214)	NC score	0.208005 (rank : 315)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	108
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	0.00869519 (rank : 215)	NC score	0.204600 (rank : 322)
Query Neighborhood Hits	453	Target Neighborhood Hits	237	Shared Neighborhood Hits	116
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

CELR2_HUMAN
θ value	0.0113563 (rank : 216)	NC score	0.174729 (rank : 374)
Query Neighborhood Hits	453	Target Neighborhood Hits	657	Shared Neighborhood Hits	234
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

KR171_HUMAN
θ value	0.0113563 (rank : 217)	NC score	0.415101 (rank : 67)
Query Neighborhood Hits	453	Target Neighborhood Hits	144	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LAMB3_HUMAN
θ value	0.0113563 (rank : 218)	NC score	0.295341 (rank : 169)
Query Neighborhood Hits	453	Target Neighborhood Hits	461	Shared Neighborhood Hits	178
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LYAM2_HUMAN
θ value	0.0113563 (rank : 219)	NC score	0.152052 (rank : 409)
Query Neighborhood Hits	453	Target Neighborhood Hits	394	Shared Neighborhood Hits	165
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NET2_HUMAN
θ value	0.0113563 (rank : 220)	NC score	0.200839 (rank : 332)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	140
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NTNG2_HUMAN
θ value	0.0113563 (rank : 221)	NC score	0.286653 (rank : 181)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	186
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

CT075_HUMAN
θ value	0.0148317 (rank : 222)	NC score	0.136917 (rank : 429)
Query Neighborhood Hits	453	Target Neighborhood Hits	387	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

KR10B_HUMAN
θ value	0.0148317 (rank : 223)	NC score	0.238932 (rank : 250)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	150
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LTB1L_MOUSE
θ value	0.0148317 (rank : 224)	NC score	0.293590 (rank : 171)
Query Neighborhood Hits	453	Target Neighborhood Hits	514	Shared Neighborhood Hits	244
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.0148317 (rank : 225)	NC score	0.292682 (rank : 172)
Query Neighborhood Hits	453	Target Neighborhood Hits	479	Shared Neighborhood Hits	233
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ADA28_MOUSE
θ value	0.0193708 (rank : 226)	NC score	0.115659 (rank : 487)
Query Neighborhood Hits	453	Target Neighborhood Hits	241	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

BOC_MOUSE
θ value	0.0193708 (rank : 227)	NC score	0.205702 (rank : 320)
Query Neighborhood Hits	453	Target Neighborhood Hits	433	Shared Neighborhood Hits	110
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CORIN_MOUSE
θ value	0.0193708 (rank : 228)	NC score	0.097591 (rank : 574)
Query Neighborhood Hits	453	Target Neighborhood Hits	451	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

KRA53_HUMAN
θ value	0.0193708 (rank : 229)	NC score	0.410333 (rank : 72)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	189
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

LRP2_HUMAN
θ value	0.0193708 (rank : 230)	NC score	0.243917 (rank : 234)
Query Neighborhood Hits	453	Target Neighborhood Hits	573	Shared Neighborhood Hits	271
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

NFASC_HUMAN
θ value	0.0193708 (rank : 231)	NC score	0.265795 (rank : 204)
Query Neighborhood Hits	453	Target Neighborhood Hits	497	Shared Neighborhood Hits	132
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

FATH_HUMAN
θ value	0.0252991 (rank : 232)	NC score	0.175891 (rank : 371)
Query Neighborhood Hits	453	Target Neighborhood Hits	570	Shared Neighborhood Hits	216
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

ITL1B_MOUSE
θ value	0.0252991 (rank : 233)	NC score	0.139924 (rank : 426)
Query Neighborhood Hits	453	Target Neighborhood Hits	36	Shared Neighborhood Hits	35
SwissProt Accessions	Q80ZA0	Gene names	Itln1b, Itln2, Itlnb
Domain Architecture	No domain graphic available
Description	Intelectin-1b precursor (Intelectin-2).

KRA51_HUMAN
θ value	0.0252991 (rank : 234)	NC score	0.409466 (rank : 74)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	166
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LAMA4_HUMAN
θ value	0.0252991 (rank : 235)	NC score	0.214054 (rank : 299)
Query Neighborhood Hits	453	Target Neighborhood Hits	708	Shared Neighborhood Hits	166
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

ADA11_HUMAN
θ value	0.0330416 (rank : 236)	NC score	0.147317 (rank : 416)
Query Neighborhood Hits	453	Target Neighborhood Hits	259	Shared Neighborhood Hits	151
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	0.0330416 (rank : 237)	NC score	0.146764 (rank : 417)
Query Neighborhood Hits	453	Target Neighborhood Hits	263	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA22_MOUSE
θ value	0.0330416 (rank : 238)	NC score	0.126756 (rank : 452)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

CD45_HUMAN
θ value	0.0330416 (rank : 239)	NC score	0.134621 (rank : 437)
Query Neighborhood Hits	453	Target Neighborhood Hits	243	Shared Neighborhood Hits	55
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

EPHA2_HUMAN
θ value	0.0330416 (rank : 240)	NC score	0.084552 (rank : 650)
Query Neighborhood Hits	453	Target Neighborhood Hits	1021	Shared Neighborhood Hits	151
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

LAMC3_HUMAN
θ value	0.0330416 (rank : 241)	NC score	0.300946 (rank : 165)
Query Neighborhood Hits	453	Target Neighborhood Hits	588	Shared Neighborhood Hits	243
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MERTK_MOUSE
θ value	0.0330416 (rank : 242)	NC score	0.078473 (rank : 704)
Query Neighborhood Hits	453	Target Neighborhood Hits	974	Shared Neighborhood Hits	113
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

CSPG2_MOUSE
θ value	0.0431538 (rank : 243)	NC score	0.194246 (rank : 344)
Query Neighborhood Hits	453	Target Neighborhood Hits	711	Shared Neighborhood Hits	191
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

EPHB6_HUMAN
θ value	0.0431538 (rank : 244)	NC score	0.095863 (rank : 586)
Query Neighborhood Hits	453	Target Neighborhood Hits	912	Shared Neighborhood Hits	157
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

I12R2_HUMAN
θ value	0.0431538 (rank : 245)	NC score	0.237584 (rank : 251)
Query Neighborhood Hits	453	Target Neighborhood Hits	163	Shared Neighborhood Hits	98
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

ITL1A_MOUSE
θ value	0.0431538 (rank : 246)	NC score	0.133206 (rank : 440)
Query Neighborhood Hits	453	Target Neighborhood Hits	33	Shared Neighborhood Hits	32
SwissProt Accessions	O88310	Gene names	Itln1a, Intl, Itln, Itlna
Domain Architecture	No domain graphic available
Description	Intelectin-1a precursor (Intestinal lactoferrin receptor) (Galactofuranose-binding lectin).

LYAM1_MOUSE
θ value	0.0431538 (rank : 247)	NC score	0.158898 (rank : 398)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	142
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TYRO3_HUMAN
θ value	0.0431538 (rank : 248)	NC score	0.092708 (rank : 602)
Query Neighborhood Hits	453	Target Neighborhood Hits	995	Shared Neighborhood Hits	112
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

HGFA_MOUSE
θ value	0.0563607 (rank : 249)	NC score	0.121513 (rank : 466)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	156
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LAMA4_MOUSE
θ value	0.0563607 (rank : 250)	NC score	0.224524 (rank : 275)
Query Neighborhood Hits	453	Target Neighborhood Hits	584	Shared Neighborhood Hits	162
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LRRN1_MOUSE
θ value	0.0563607 (rank : 251)	NC score	0.079175 (rank : 698)
Query Neighborhood Hits	453	Target Neighborhood Hits	508	Shared Neighborhood Hits	85
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LYAM2_MOUSE
θ value	0.0563607 (rank : 252)	NC score	0.161590 (rank : 393)
Query Neighborhood Hits	453	Target Neighborhood Hits	420	Shared Neighborhood Hits	186
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NTNG2_MOUSE
θ value	0.0563607 (rank : 253)	NC score	0.289162 (rank : 179)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	190
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PGBM_MOUSE
θ value	0.0563607 (rank : 254)	NC score	0.304741 (rank : 161)
Query Neighborhood Hits	453	Target Neighborhood Hits	1073	Shared Neighborhood Hits	324
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PTPRM_HUMAN
θ value	0.0563607 (rank : 255)	NC score	0.219667 (rank : 287)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	117
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	0.0563607 (rank : 256)	NC score	0.221202 (rank : 280)
Query Neighborhood Hits	453	Target Neighborhood Hits	238	Shared Neighborhood Hits	117
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

ADM1B_MOUSE
θ value	0.0736092 (rank : 257)	NC score	0.099679 (rank : 555)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

LAMA3_MOUSE
θ value	0.0736092 (rank : 258)	NC score	0.271257 (rank : 199)
Query Neighborhood Hits	453	Target Neighborhood Hits	859	Shared Neighborhood Hits	241
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMC2_HUMAN
θ value	0.0736092 (rank : 259)	NC score	0.276171 (rank : 195)
Query Neighborhood Hits	453	Target Neighborhood Hits	715	Shared Neighborhood Hits	228
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MYPC1_HUMAN
θ value	0.0736092 (rank : 260)	NC score	0.181959 (rank : 362)
Query Neighborhood Hits	453	Target Neighborhood Hits	303	Shared Neighborhood Hits	97
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

EPHA4_HUMAN
θ value	0.0961366 (rank : 261)	NC score	0.083636 (rank : 661)
Query Neighborhood Hits	453	Target Neighborhood Hits	975	Shared Neighborhood Hits	142
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHAA_HUMAN
θ value	0.0961366 (rank : 262)	NC score	0.078309 (rank : 706)
Query Neighborhood Hits	453	Target Neighborhood Hits	960	Shared Neighborhood Hits	133
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB3_MOUSE
θ value	0.0961366 (rank : 263)	NC score	0.084929 (rank : 646)
Query Neighborhood Hits	453	Target Neighborhood Hits	996	Shared Neighborhood Hits	142
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

INSR_MOUSE
θ value	0.0961366 (rank : 264)	NC score	0.061933 (rank : 833)
Query Neighborhood Hits	453	Target Neighborhood Hits	968	Shared Neighborhood Hits	141
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

KRA54_HUMAN
θ value	0.0961366 (rank : 265)	NC score	0.371001 (rank : 102)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	157
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LAMB1_HUMAN
θ value	0.0961366 (rank : 266)	NC score	0.286002 (rank : 184)
Query Neighborhood Hits	453	Target Neighborhood Hits	1018	Shared Neighborhood Hits	240
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NELL1_HUMAN
θ value	0.0961366 (rank : 267)	NC score	0.301960 (rank : 164)
Query Neighborhood Hits	453	Target Neighborhood Hits	451	Shared Neighborhood Hits	237
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

BAI1_MOUSE
θ value	0.125558 (rank : 268)	NC score	0.027050 (rank : 954)
Query Neighborhood Hits	453	Target Neighborhood Hits	340	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CSPG2_HUMAN
θ value	0.125558 (rank : 269)	NC score	0.192837 (rank : 349)
Query Neighborhood Hits	453	Target Neighborhood Hits	681	Shared Neighborhood Hits	194
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

EPHA4_MOUSE
θ value	0.125558 (rank : 270)	NC score	0.084496 (rank : 652)
Query Neighborhood Hits	453	Target Neighborhood Hits	982	Shared Neighborhood Hits	148
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

I12R1_HUMAN
θ value	0.125558 (rank : 271)	NC score	0.127175 (rank : 451)
Query Neighborhood Hits	453	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

KRA92_HUMAN
θ value	0.125558 (rank : 272)	NC score	0.232471 (rank : 262)
Query Neighborhood Hits	453	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LRP8_MOUSE
θ value	0.125558 (rank : 273)	NC score	0.219921 (rank : 286)
Query Neighborhood Hits	453	Target Neighborhood Hits	385	Shared Neighborhood Hits	188
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	0.125558 (rank : 274)	NC score	0.292409 (rank : 173)
Query Neighborhood Hits	453	Target Neighborhood Hits	553	Shared Neighborhood Hits	243
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.125558 (rank : 275)	NC score	0.291594 (rank : 174)
Query Neighborhood Hits	453	Target Neighborhood Hits	502	Shared Neighborhood Hits	233
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NCA11_MOUSE
θ value	0.125558 (rank : 276)	NC score	0.170593 (rank : 378)
Query Neighborhood Hits	453	Target Neighborhood Hits	661	Shared Neighborhood Hits	111
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

AD26A_MOUSE
θ value	0.163984 (rank : 277)	NC score	0.076974 (rank : 713)
Query Neighborhood Hits	453	Target Neighborhood Hits	165	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

CSF3R_MOUSE
θ value	0.163984 (rank : 278)	NC score	0.156089 (rank : 404)
Query Neighborhood Hits	453	Target Neighborhood Hits	104	Shared Neighborhood Hits	68
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

EDIL3_MOUSE
θ value	0.163984 (rank : 279)	NC score	0.263117 (rank : 208)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	188
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EPHB6_MOUSE
θ value	0.163984 (rank : 280)	NC score	0.089716 (rank : 611)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	141
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

KRA45_HUMAN
θ value	0.163984 (rank : 281)	NC score	0.251093 (rank : 225)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LDLR_MOUSE
θ value	0.163984 (rank : 282)	NC score	0.211912 (rank : 305)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	206
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

NELL2_HUMAN
θ value	0.163984 (rank : 283)	NC score	0.306899 (rank : 156)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	243
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

TRBM_HUMAN
θ value	0.163984 (rank : 284)	NC score	0.251867 (rank : 222)
Query Neighborhood Hits	453	Target Neighborhood Hits	339	Shared Neighborhood Hits	178
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	0.163984 (rank : 285)	NC score	0.239814 (rank : 246)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	187
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

VWF_HUMAN
θ value	0.163984 (rank : 286)	NC score	0.190667 (rank : 355)
Query Neighborhood Hits	453	Target Neighborhood Hits	396	Shared Neighborhood Hits	175
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ADA19_MOUSE
θ value	0.21417 (rank : 287)	NC score	0.112913 (rank : 491)
Query Neighborhood Hits	453	Target Neighborhood Hits	315	Shared Neighborhood Hits	162
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA22_HUMAN
θ value	0.21417 (rank : 288)	NC score	0.116147 (rank : 485)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	117
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

AGRIN_HUMAN
θ value	0.21417 (rank : 289)	NC score	0.313979 (rank : 142)
Query Neighborhood Hits	453	Target Neighborhood Hits	582	Shared Neighborhood Hits	260
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

EDIL3_HUMAN
θ value	0.21417 (rank : 290)	NC score	0.240597 (rank : 244)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	172
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

GAS6_MOUSE
θ value	0.21417 (rank : 291)	NC score	0.249629 (rank : 228)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	196
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

HTRA3_MOUSE
θ value	0.21417 (rank : 292)	NC score	0.032888 (rank : 953)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

KR107_HUMAN
θ value	0.21417 (rank : 293)	NC score	0.310202 (rank : 148)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	192
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA56_HUMAN
θ value	0.21417 (rank : 294)	NC score	0.370053 (rank : 103)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	130
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA59_HUMAN
θ value	0.21417 (rank : 295)	NC score	0.385602 (rank : 95)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	166
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMC2_MOUSE
θ value	0.21417 (rank : 296)	NC score	0.289258 (rank : 178)
Query Neighborhood Hits	453	Target Neighborhood Hits	614	Shared Neighborhood Hits	225
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LTBP3_HUMAN
θ value	0.21417 (rank : 297)	NC score	0.286496 (rank : 182)
Query Neighborhood Hits	453	Target Neighborhood Hits	502	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MYPC2_HUMAN
θ value	0.21417 (rank : 298)	NC score	0.199059 (rank : 340)
Query Neighborhood Hits	453	Target Neighborhood Hits	316	Shared Neighborhood Hits	106
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NCA12_MOUSE
θ value	0.21417 (rank : 299)	NC score	0.159239 (rank : 397)
Query Neighborhood Hits	453	Target Neighborhood Hits	399	Shared Neighborhood Hits	96
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

NPHN_HUMAN
θ value	0.21417 (rank : 300)	NC score	0.199435 (rank : 337)
Query Neighborhood Hits	453	Target Neighborhood Hits	362	Shared Neighborhood Hits	96
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

UROM_MOUSE
θ value	0.21417 (rank : 301)	NC score	0.231518 (rank : 266)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	176
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ADA18_MOUSE
θ value	0.279714 (rank : 302)	NC score	0.125935 (rank : 454)
Query Neighborhood Hits	453	Target Neighborhood Hits	227	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA19_HUMAN
θ value	0.279714 (rank : 303)	NC score	0.113083 (rank : 490)
Query Neighborhood Hits	453	Target Neighborhood Hits	381	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA32_HUMAN
θ value	0.279714 (rank : 304)	NC score	0.108829 (rank : 507)
Query Neighborhood Hits	453	Target Neighborhood Hits	216	Shared Neighborhood Hits	136
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADAM9_HUMAN
θ value	0.279714 (rank : 305)	NC score	0.111995 (rank : 497)
Query Neighborhood Hits	453	Target Neighborhood Hits	243	Shared Neighborhood Hits	142
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

CD45_MOUSE
θ value	0.279714 (rank : 306)	NC score	0.118764 (rank : 477)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	51
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CHL1_MOUSE
θ value	0.279714 (rank : 307)	NC score	0.233490 (rank : 260)
Query Neighborhood Hits	453	Target Neighborhood Hits	402	Shared Neighborhood Hits	117
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

EPHA2_MOUSE
θ value	0.279714 (rank : 308)	NC score	0.082690 (rank : 670)
Query Neighborhood Hits	453	Target Neighborhood Hits	1020	Shared Neighborhood Hits	154
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

INSR_HUMAN
θ value	0.279714 (rank : 309)	NC score	0.061450 (rank : 838)
Query Neighborhood Hits	453	Target Neighborhood Hits	963	Shared Neighborhood Hits	144
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

KRA52_HUMAN
θ value	0.279714 (rank : 310)	NC score	0.335218 (rank : 126)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	140
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

MATN2_HUMAN
θ value	0.279714 (rank : 311)	NC score	0.261164 (rank : 213)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	177
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

ADA12_MOUSE
θ value	0.365318 (rank : 312)	NC score	0.091398 (rank : 607)
Query Neighborhood Hits	453	Target Neighborhood Hits	474	Shared Neighborhood Hits	113
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

EPHB4_MOUSE
θ value	0.365318 (rank : 313)	NC score	0.090130 (rank : 610)
Query Neighborhood Hits	453	Target Neighborhood Hits	1013	Shared Neighborhood Hits	180
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

ERBB4_HUMAN
θ value	0.365318 (rank : 314)	NC score	0.034535 (rank : 952)
Query Neighborhood Hits	453	Target Neighborhood Hits	910	Shared Neighborhood Hits	93
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

I12R2_MOUSE
θ value	0.365318 (rank : 315)	NC score	0.208772 (rank : 312)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	92
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

ITLN2_HUMAN
θ value	0.365318 (rank : 316)	NC score	0.112653 (rank : 493)
Query Neighborhood Hits	453	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WWU7	Gene names	ITLN2
Domain Architecture	No domain graphic available
Description	Intelectin-2 precursor (Endothelial lectin HL-2).

SPEG_MOUSE
θ value	0.365318 (rank : 317)	NC score	0.066335 (rank : 787)
Query Neighborhood Hits	453	Target Neighborhood Hits	1959	Shared Neighborhood Hits	118
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

NTNG1_MOUSE
θ value	0.47712 (rank : 318)	NC score	0.265993 (rank : 203)
Query Neighborhood Hits	453	Target Neighborhood Hits	246	Shared Neighborhood Hits	169
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

VASN_HUMAN
θ value	0.47712 (rank : 319)	NC score	0.077708 (rank : 708)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	120
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ZAN_MOUSE
θ value	0.47712 (rank : 320)	NC score	0.264547 (rank : 207)
Query Neighborhood Hits	453	Target Neighborhood Hits	808	Shared Neighborhood Hits	271
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ADA12_HUMAN
θ value	0.62314 (rank : 321)	NC score	0.098651 (rank : 569)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	117
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

EPHB3_HUMAN
θ value	0.62314 (rank : 322)	NC score	0.084642 (rank : 649)
Query Neighborhood Hits	453	Target Neighborhood Hits	996	Shared Neighborhood Hits	147
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

KR104_HUMAN
θ value	0.62314 (rank : 323)	NC score	0.318160 (rank : 140)
Query Neighborhood Hits	453	Target Neighborhood Hits	313	Shared Neighborhood Hits	177
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LRRN1_HUMAN
θ value	0.62314 (rank : 324)	NC score	0.080468 (rank : 688)
Query Neighborhood Hits	453	Target Neighborhood Hits	518	Shared Neighborhood Hits	88
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

MYOM1_HUMAN
θ value	0.62314 (rank : 325)	NC score	0.262930 (rank : 209)
Query Neighborhood Hits	453	Target Neighborhood Hits	405	Shared Neighborhood Hits	123
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NELL2_MOUSE
θ value	0.62314 (rank : 326)	NC score	0.305732 (rank : 157)
Query Neighborhood Hits	453	Target Neighborhood Hits	436	Shared Neighborhood Hits	241
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

PUNC_HUMAN
θ value	0.62314 (rank : 327)	NC score	0.244590 (rank : 233)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	123
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TSP1_MOUSE
θ value	0.62314 (rank : 328)	NC score	0.152230 (rank : 408)
Query Neighborhood Hits	453	Target Neighborhood Hits	396	Shared Neighborhood Hits	179
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

VEGFD_MOUSE
θ value	0.62314 (rank : 329)	NC score	0.026198 (rank : 955)
Query Neighborhood Hits	453	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P97946	Gene names	Figf, Vegfd
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

ADAM9_MOUSE
θ value	0.813845 (rank : 330)	NC score	0.118881 (rank : 475)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	151
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ATS9_HUMAN
θ value	0.813845 (rank : 331)	NC score	0.046940 (rank : 944)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	82
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

CD248_HUMAN
θ value	0.813845 (rank : 332)	NC score	0.161415 (rank : 394)
Query Neighborhood Hits	453	Target Neighborhood Hits	679	Shared Neighborhood Hits	174
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

EPHA3_MOUSE
θ value	0.813845 (rank : 333)	NC score	0.082966 (rank : 669)
Query Neighborhood Hits	453	Target Neighborhood Hits	1009	Shared Neighborhood Hits	168
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHB1_HUMAN
θ value	0.813845 (rank : 334)	NC score	0.076618 (rank : 716)
Query Neighborhood Hits	453	Target Neighborhood Hits	988	Shared Neighborhood Hits	151
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

FLRT3_HUMAN
θ value	0.813845 (rank : 335)	NC score	0.041423 (rank : 946)
Query Neighborhood Hits	453	Target Neighborhood Hits	281	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZU0, Q96K39, Q96K42, Q96KB1, Q9P259	Gene names	FLRT3, KIAA1469
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT3 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 3).

HTRA3_HUMAN
θ value	0.813845 (rank : 336)	NC score	0.024311 (rank : 957)
Query Neighborhood Hits	453	Target Neighborhood Hits	152	Shared Neighborhood Hits	24
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

ITLN1_HUMAN
θ value	0.813845 (rank : 337)	NC score	0.088547 (rank : 619)
Query Neighborhood Hits	453	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WWA0, Q6YDJ3, Q9NP67	Gene names	ITLN1, INTL, ITLN, LFR
Domain Architecture	No domain graphic available
Description	Intelectin-1 precursor (Intestinal lactoferrin receptor) (Galactofuranose-binding lectin) (Endothelial lectin HL-1) (Omentin).

KR101_HUMAN
θ value	0.813845 (rank : 338)	NC score	0.278922 (rank : 189)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	150
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	0.813845 (rank : 339)	NC score	0.281986 (rank : 186)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	156
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

LTBP3_MOUSE
θ value	0.813845 (rank : 340)	NC score	0.280195 (rank : 187)
Query Neighborhood Hits	453	Target Neighborhood Hits	475	Shared Neighborhood Hits	259
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MYPC3_MOUSE
θ value	0.813845 (rank : 341)	NC score	0.193644 (rank : 346)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	106
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NCA11_HUMAN
θ value	0.813845 (rank : 342)	NC score	0.167247 (rank : 385)
Query Neighborhood Hits	453	Target Neighborhood Hits	443	Shared Neighborhood Hits	107
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

PROC_HUMAN
θ value	0.813845 (rank : 343)	NC score	0.094293 (rank : 597)
Query Neighborhood Hits	453	Target Neighborhood Hits	406	Shared Neighborhood Hits	167
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TPA_HUMAN
θ value	0.813845 (rank : 344)	NC score	0.061015 (rank : 844)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	119
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	0.813845 (rank : 345)	NC score	0.061276 (rank : 840)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	121
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRIM9_HUMAN
θ value	0.813845 (rank : 346)	NC score	0.041621 (rank : 945)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	42
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	0.813845 (rank : 347)	NC score	0.036424 (rank : 949)
Query Neighborhood Hits	453	Target Neighborhood Hits	274	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TYRO3_MOUSE
θ value	0.813845 (rank : 348)	NC score	0.086678 (rank : 628)
Query Neighborhood Hits	453	Target Neighborhood Hits	1007	Shared Neighborhood Hits	115
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

VEGFC_HUMAN
θ value	0.813845 (rank : 349)	NC score	0.121161 (rank : 468)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADA23_HUMAN
θ value	1.06291 (rank : 350)	NC score	0.130908 (rank : 443)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	146
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	1.06291 (rank : 351)	NC score	0.128121 (rank : 450)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	153
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CUBN_HUMAN
θ value	1.06291 (rank : 352)	NC score	0.261565 (rank : 210)
Query Neighborhood Hits	453	Target Neighborhood Hits	482	Shared Neighborhood Hits	230
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

EPHA7_HUMAN
θ value	1.06291 (rank : 353)	NC score	0.089513 (rank : 613)
Query Neighborhood Hits	453	Target Neighborhood Hits	1053	Shared Neighborhood Hits	189
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

IL6RB_HUMAN
θ value	1.06291 (rank : 354)	NC score	0.201745 (rank : 329)
Query Neighborhood Hits	453	Target Neighborhood Hits	181	Shared Neighborhood Hits	103
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

KRA55_HUMAN
θ value	1.06291 (rank : 355)	NC score	0.360147 (rank : 107)
Query Neighborhood Hits	453	Target Neighborhood Hits	257	Shared Neighborhood Hits	152
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NTNG1_HUMAN
θ value	1.06291 (rank : 356)	NC score	0.264631 (rank : 206)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	171
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PROC_MOUSE
θ value	1.06291 (rank : 357)	NC score	0.117266 (rank : 483)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	174
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CELR2_MOUSE
θ value	1.38821 (rank : 358)	NC score	0.156088 (rank : 405)
Query Neighborhood Hits	453	Target Neighborhood Hits	584	Shared Neighborhood Hits	211
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CFAI_HUMAN
θ value	1.38821 (rank : 359)	NC score	0.036274 (rank : 950)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	58
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	1.38821 (rank : 360)	NC score	0.037353 (rank : 948)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	63
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

EPHA3_HUMAN
θ value	1.38821 (rank : 361)	NC score	0.079212 (rank : 697)
Query Neighborhood Hits	453	Target Neighborhood Hits	1005	Shared Neighborhood Hits	167
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHB4_HUMAN
θ value	1.38821 (rank : 362)	NC score	0.096233 (rank : 583)
Query Neighborhood Hits	453	Target Neighborhood Hits	1056	Shared Neighborhood Hits	196
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

FRAS1_HUMAN
θ value	1.38821 (rank : 363)	NC score	0.199665 (rank : 335)
Query Neighborhood Hits	453	Target Neighborhood Hits	759	Shared Neighborhood Hits	235
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GAS6_HUMAN
θ value	1.38821 (rank : 364)	NC score	0.248373 (rank : 230)
Query Neighborhood Hits	453	Target Neighborhood Hits	348	Shared Neighborhood Hits	201
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KR511_HUMAN
θ value	1.38821 (rank : 365)	NC score	0.347107 (rank : 115)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	131
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

TSP1_HUMAN
θ value	1.38821 (rank : 366)	NC score	0.151436 (rank : 410)
Query Neighborhood Hits	453	Target Neighborhood Hits	389	Shared Neighborhood Hits	180
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

CHL1_HUMAN
θ value	1.81305 (rank : 367)	NC score	0.253744 (rank : 219)
Query Neighborhood Hits	453	Target Neighborhood Hits	413	Shared Neighborhood Hits	119
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

CO8A_MOUSE
θ value	1.81305 (rank : 368)	NC score	0.054994 (rank : 896)
Query Neighborhood Hits	453	Target Neighborhood Hits	182	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

EGLN_MOUSE
θ value	1.81305 (rank : 369)	NC score	0.011117 (rank : 962)
Query Neighborhood Hits	453	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q63961, Q61520	Gene names	Eng, Edg
Domain Architecture
Description	Endoglin precursor (Cell surface MJ7/18 antigen).

HGFA_HUMAN
θ value	1.81305 (rank : 370)	NC score	0.119213 (rank : 472)
Query Neighborhood Hits	453	Target Neighborhood Hits	436	Shared Neighborhood Hits	159
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

KRA42_HUMAN
θ value	1.81305 (rank : 371)	NC score	0.182171 (rank : 361)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

MYOM1_MOUSE
θ value	1.81305 (rank : 372)	NC score	0.241807 (rank : 240)
Query Neighborhood Hits	453	Target Neighborhood Hits	415	Shared Neighborhood Hits	129
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

MYPC3_HUMAN
θ value	1.81305 (rank : 373)	NC score	0.201073 (rank : 330)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	107
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

VEGFC_MOUSE
θ value	1.81305 (rank : 374)	NC score	0.089438 (rank : 614)
Query Neighborhood Hits	453	Target Neighborhood Hits	119	Shared Neighborhood Hits	80
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADAM7_HUMAN
θ value	2.36792 (rank : 375)	NC score	0.094026 (rank : 598)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	145
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

EPHA7_MOUSE
θ value	2.36792 (rank : 376)	NC score	0.086804 (rank : 627)
Query Neighborhood Hits	453	Target Neighborhood Hits	1025	Shared Neighborhood Hits	167
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

FBLN1_MOUSE
θ value	2.36792 (rank : 377)	NC score	0.221646 (rank : 277)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	186
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

KR106_HUMAN
θ value	2.36792 (rank : 378)	NC score	0.307752 (rank : 154)
Query Neighborhood Hits	453	Target Neighborhood Hits	347	Shared Neighborhood Hits	194
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR108_HUMAN
θ value	2.36792 (rank : 379)	NC score	0.234074 (rank : 258)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	132
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	2.36792 (rank : 380)	NC score	0.229952 (rank : 267)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	138
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

LRFN4_HUMAN
θ value	2.36792 (rank : 381)	NC score	0.091863 (rank : 605)
Query Neighborhood Hits	453	Target Neighborhood Hits	462	Shared Neighborhood Hits	87
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRP6_HUMAN
θ value	2.36792 (rank : 382)	NC score	0.118724 (rank : 478)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	101
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	2.36792 (rank : 383)	NC score	0.115447 (rank : 488)
Query Neighborhood Hits	453	Target Neighborhood Hits	232	Shared Neighborhood Hits	98
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

PLAP_HUMAN
θ value	2.36792 (rank : 384)	NC score	-0.000068 (rank : 971)
Query Neighborhood Hits	453	Target Neighborhood Hits	266	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

PTPRO_HUMAN
θ value	2.36792 (rank : 385)	NC score	0.174286 (rank : 375)
Query Neighborhood Hits	453	Target Neighborhood Hits	139	Shared Neighborhood Hits	58
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

WNK2_HUMAN
θ value	2.36792 (rank : 386)	NC score	0.000397 (rank : 968)
Query Neighborhood Hits	453	Target Neighborhood Hits	1407	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

BAI2_MOUSE
θ value	3.0926 (rank : 387)	NC score	0.022991 (rank : 958)
Query Neighborhood Hits	453	Target Neighborhood Hits	323	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CORIN_HUMAN
θ value	3.0926 (rank : 388)	NC score	0.100008 (rank : 552)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CSPG3_MOUSE
θ value	3.0926 (rank : 389)	NC score	0.197203 (rank : 342)
Query Neighborhood Hits	453	Target Neighborhood Hits	657	Shared Neighborhood Hits	190
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

EGFL7_MOUSE
θ value	3.0926 (rank : 390)	NC score	0.251293 (rank : 224)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGF_MOUSE
θ value	3.0926 (rank : 391)	NC score	0.237237 (rank : 252)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	196
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ENPP2_MOUSE
θ value	3.0926 (rank : 392)	NC score	0.035323 (rank : 951)
Query Neighborhood Hits	453	Target Neighborhood Hits	66	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

EPHA1_HUMAN
θ value	3.0926 (rank : 393)	NC score	0.062706 (rank : 825)
Query Neighborhood Hits	453	Target Neighborhood Hits	997	Shared Neighborhood Hits	144
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

I12R1_MOUSE
θ value	3.0926 (rank : 394)	NC score	0.123985 (rank : 460)
Query Neighborhood Hits	453	Target Neighborhood Hits	70	Shared Neighborhood Hits	49
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

IL6RB_MOUSE
θ value	3.0926 (rank : 395)	NC score	0.205812 (rank : 319)
Query Neighborhood Hits	453	Target Neighborhood Hits	168	Shared Neighborhood Hits	100
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

KR412_HUMAN
θ value	3.0926 (rank : 396)	NC score	0.218871 (rank : 291)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR510_HUMAN
θ value	3.0926 (rank : 397)	NC score	0.307104 (rank : 155)
Query Neighborhood Hits	453	Target Neighborhood Hits	217	Shared Neighborhood Hits	128
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

LYAM1_HUMAN
θ value	3.0926 (rank : 398)	NC score	0.135334 (rank : 433)
Query Neighborhood Hits	453	Target Neighborhood Hits	315	Shared Neighborhood Hits	141
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MUC5B_HUMAN
θ value	3.0926 (rank : 399)	NC score	0.147930 (rank : 414)
Query Neighborhood Hits	453	Target Neighborhood Hits	1020	Shared Neighborhood Hits	218
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NPHN_MOUSE
θ value	3.0926 (rank : 400)	NC score	0.183885 (rank : 358)
Query Neighborhood Hits	453	Target Neighborhood Hits	370	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

ROS_HUMAN
θ value	3.0926 (rank : 401)	NC score	0.075189 (rank : 726)
Query Neighborhood Hits	453	Target Neighborhood Hits	907	Shared Neighborhood Hits	135
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SSPO_MOUSE
θ value	3.0926 (rank : 402)	NC score	0.199492 (rank : 336)
Query Neighborhood Hits	453	Target Neighborhood Hits	800	Shared Neighborhood Hits	267
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SUSD1_HUMAN
θ value	3.0926 (rank : 403)	NC score	0.217088 (rank : 295)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	154
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

VASN_MOUSE
θ value	3.0926 (rank : 404)	NC score	0.072307 (rank : 751)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	116
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

BAI2_HUMAN
θ value	4.03905 (rank : 405)	NC score	0.022537 (rank : 959)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	35
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CD248_MOUSE
θ value	4.03905 (rank : 406)	NC score	0.158225 (rank : 400)
Query Neighborhood Hits	453	Target Neighborhood Hits	578	Shared Neighborhood Hits	153
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CO8B_MOUSE
θ value	4.03905 (rank : 407)	NC score	0.085089 (rank : 643)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

FBLN1_HUMAN
θ value	4.03905 (rank : 408)	NC score	0.221402 (rank : 278)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	184
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

KRA11_HUMAN
θ value	4.03905 (rank : 409)	NC score	0.241945 (rank : 239)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	99
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA94_HUMAN
θ value	4.03905 (rank : 410)	NC score	0.221207 (rank : 279)
Query Neighborhood Hits	453	Target Neighborhood Hits	204	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

LAMA3_HUMAN
θ value	4.03905 (rank : 411)	NC score	0.223317 (rank : 276)
Query Neighborhood Hits	453	Target Neighborhood Hits	760	Shared Neighborhood Hits	196
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LRP5_HUMAN
θ value	4.03905 (rank : 412)	NC score	0.110304 (rank : 501)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	101
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	4.03905 (rank : 413)	NC score	0.109596 (rank : 504)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	106
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MEGF9_MOUSE
θ value	4.03905 (rank : 414)	NC score	0.304715 (rank : 162)
Query Neighborhood Hits	453	Target Neighborhood Hits	896	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MUC13_MOUSE
θ value	4.03905 (rank : 415)	NC score	0.112738 (rank : 492)
Query Neighborhood Hits	453	Target Neighborhood Hits	447	Shared Neighborhood Hits	131
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

UROL1_HUMAN
θ value	4.03905 (rank : 416)	NC score	0.099986 (rank : 553)
Query Neighborhood Hits	453	Target Neighborhood Hits	213	Shared Neighborhood Hits	87
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

VLDLR_HUMAN
θ value	4.03905 (rank : 417)	NC score	0.219574 (rank : 289)
Query Neighborhood Hits	453	Target Neighborhood Hits	383	Shared Neighborhood Hits	200
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ZBT16_HUMAN
θ value	4.03905 (rank : 418)	NC score	-0.011991 (rank : 973)
Query Neighborhood Hits	453	Target Neighborhood Hits	1010	Shared Neighborhood Hits	11
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

EPHA5_HUMAN
θ value	5.27518 (rank : 419)	NC score	0.080879 (rank : 685)
Query Neighborhood Hits	453	Target Neighborhood Hits	1009	Shared Neighborhood Hits	155
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

HCFC2_HUMAN
θ value	5.27518 (rank : 420)	NC score	0.094868 (rank : 591)
Query Neighborhood Hits	453	Target Neighborhood Hits	154	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

IL2RB_MOUSE
θ value	5.27518 (rank : 421)	NC score	0.010261 (rank : 964)
Query Neighborhood Hits	453	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

K0319_MOUSE
θ value	5.27518 (rank : 422)	NC score	0.040910 (rank : 947)
Query Neighborhood Hits	453	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

NID1_MOUSE
θ value	5.27518 (rank : 423)	NC score	0.220768 (rank : 282)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	183
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	5.27518 (rank : 424)	NC score	0.231524 (rank : 265)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	190
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

SHAN2_HUMAN
θ value	5.27518 (rank : 425)	NC score	0.007367 (rank : 965)
Query Neighborhood Hits	453	Target Neighborhood Hits	346	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SPEG_HUMAN
θ value	5.27518 (rank : 426)	NC score	0.065598 (rank : 795)
Query Neighborhood Hits	453	Target Neighborhood Hits	1762	Shared Neighborhood Hits	117
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TSP2_MOUSE
θ value	5.27518 (rank : 427)	NC score	0.123076 (rank : 463)
Query Neighborhood Hits	453	Target Neighborhood Hits	352	Shared Neighborhood Hits	169
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

VLDLR_MOUSE
θ value	5.27518 (rank : 428)	NC score	0.219505 (rank : 290)
Query Neighborhood Hits	453	Target Neighborhood Hits	360	Shared Neighborhood Hits	192
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ATP9B_HUMAN
θ value	6.88961 (rank : 429)	NC score	0.000133 (rank : 969)
Query Neighborhood Hits	453	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	O43861, O60872	Gene names	ATP9B, ATPIIB, NEO1L
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1).

CAD16_HUMAN
θ value	6.88961 (rank : 430)	NC score	0.012276 (rank : 961)
Query Neighborhood Hits	453	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CO8B_HUMAN
θ value	6.88961 (rank : 431)	NC score	0.062136 (rank : 830)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	83
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

KR103_HUMAN
θ value	6.88961 (rank : 432)	NC score	0.182171 (rank : 360)
Query Neighborhood Hits	453	Target Neighborhood Hits	212	Shared Neighborhood Hits	124
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KRA44_HUMAN
θ value	6.88961 (rank : 433)	NC score	0.251336 (rank : 223)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

MMRN1_HUMAN
θ value	6.88961 (rank : 434)	NC score	0.094840 (rank : 592)
Query Neighborhood Hits	453	Target Neighborhood Hits	636	Shared Neighborhood Hits	112
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

PLAP_MOUSE
θ value	6.88961 (rank : 435)	NC score	-0.001231 (rank : 972)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

SCUB3_HUMAN
θ value	6.88961 (rank : 436)	NC score	0.243864 (rank : 235)
Query Neighborhood Hits	453	Target Neighborhood Hits	428	Shared Neighborhood Hits	217
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

APR3_MOUSE
θ value	8.99809 (rank : 437)	NC score	0.086114 (rank : 634)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ATP9B_MOUSE
θ value	8.99809 (rank : 438)	NC score	0.000007 (rank : 970)
Query Neighborhood Hits	453	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P98195, Q99LI3	Gene names	Atp9b
Domain Architecture
Description	Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1).

CO6_HUMAN
θ value	8.99809 (rank : 439)	NC score	0.099409 (rank : 560)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	132
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

EGFL7_HUMAN
θ value	8.99809 (rank : 440)	NC score	0.261233 (rank : 212)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

FREM2_MOUSE
θ value	8.99809 (rank : 441)	NC score	0.006588 (rank : 966)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

I13R1_HUMAN
θ value	8.99809 (rank : 442)	NC score	0.010479 (rank : 963)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

K0319_HUMAN
θ value	8.99809 (rank : 443)	NC score	0.025442 (rank : 956)
Query Neighborhood Hits	453	Target Neighborhood Hits	154	Shared Neighborhood Hits	24
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

KR10C_HUMAN
θ value	8.99809 (rank : 444)	NC score	0.243383 (rank : 236)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	135
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA47_HUMAN
θ value	8.99809 (rank : 445)	NC score	0.241710 (rank : 242)
Query Neighborhood Hits	453	Target Neighborhood Hits	204	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

LDLR_HUMAN
θ value	8.99809 (rank : 446)	NC score	0.225984 (rank : 274)
Query Neighborhood Hits	453	Target Neighborhood Hits	375	Shared Neighborhood Hits	208
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MERTK_HUMAN
θ value	8.99809 (rank : 447)	NC score	0.078500 (rank : 703)
Query Neighborhood Hits	453	Target Neighborhood Hits	988	Shared Neighborhood Hits	109
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MFGM_MOUSE
θ value	8.99809 (rank : 448)	NC score	0.192954 (rank : 347)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	142
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

PTPRK_HUMAN
θ value	8.99809 (rank : 449)	NC score	0.169510 (rank : 381)
Query Neighborhood Hits	453	Target Neighborhood Hits	228	Shared Neighborhood Hits	104
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PUNC_MOUSE
θ value	8.99809 (rank : 450)	NC score	0.242185 (rank : 237)
Query Neighborhood Hits	453	Target Neighborhood Hits	501	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

SEPP1_MOUSE
θ value	8.99809 (rank : 451)	NC score	0.016956 (rank : 960)
Query Neighborhood Hits	453	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P70274, Q9Z2T7	Gene names	Sepp1, Selp
Domain Architecture
Description	Selenoprotein P precursor (SeP) (Plasma selenoprotein P).

SYNP2_HUMAN
θ value	8.99809 (rank : 452)	NC score	0.000603 (rank : 967)
Query Neighborhood Hits	453	Target Neighborhood Hits	323	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

VWF_MOUSE
θ value	8.99809 (rank : 453)	NC score	0.163998 (rank : 389)
Query Neighborhood Hits	453	Target Neighborhood Hits	381	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ADA10_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.111264 (rank : 500)
Query Neighborhood Hits	453	Target Neighborhood Hits	189	Shared Neighborhood Hits	110
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.112285 (rank : 495)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	105
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA17_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.102185 (rank : 541)
Query Neighborhood Hits	453	Target Neighborhood Hits	223	Shared Neighborhood Hits	117
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.087173 (rank : 625)
Query Neighborhood Hits	453	Target Neighborhood Hits	201	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.098713 (rank : 568)
Query Neighborhood Hits	453	Target Neighborhood Hits	184	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA20_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.063101 (rank : 821)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.074530 (rank : 731)
Query Neighborhood Hits	453	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.078377 (rank : 705)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA24_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.102742 (rank : 538)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	142
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.085551 (rank : 639)
Query Neighborhood Hits	453	Target Neighborhood Hits	213	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA29_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.076583 (rank : 718)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA30_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.087383 (rank : 624)
Query Neighborhood Hits	453	Target Neighborhood Hits	391	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA33_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.107295 (rank : 512)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.112411 (rank : 494)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	136
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.100067 (rank : 551)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	113
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.115664 (rank : 486)
Query Neighborhood Hits	453	Target Neighborhood Hits	209	Shared Neighborhood Hits	135
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.085594 (rank : 636)
Query Neighborhood Hits	453	Target Neighborhood Hits	200	Shared Neighborhood Hits	120
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADEC1_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.050028 (rank : 943)
Query Neighborhood Hits	453	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.053234 (rank : 913)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADIPO_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.061467 (rank : 836)
Query Neighborhood Hits	453	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

ADIPO_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.060541 (rank : 846)
Query Neighborhood Hits	453	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

ADM1A_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.097173 (rank : 578)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	142
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ANKF1_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.075113 (rank : 728)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

APR3_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.079742 (rank : 694)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

ASTN_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.060434 (rank : 848)
Query Neighborhood Hits	453	Target Neighborhood Hits	105	Shared Neighborhood Hits	53
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.063241 (rank : 816)
Query Neighborhood Hits	453	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATL3_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.081979 (rank : 678)
Query Neighborhood Hits	453	Target Neighborhood Hits	414	Shared Neighborhood Hits	103
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

BASI_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.094745 (rank : 594)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	57
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

BASI_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.092032 (rank : 604)
Query Neighborhood Hits	453	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

BMP1_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.050618 (rank : 936)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	89
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.051257 (rank : 931)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMPER_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.070592 (rank : 759)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.088023 (rank : 621)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

C1QA_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.064155 (rank : 808)
Query Neighborhood Hits	453	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

C1QC_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.055186 (rank : 889)
Query Neighborhood Hits	453	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

C1QR1_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.234406 (rank : 257)
Query Neighborhood Hits	453	Target Neighborhood Hits	493	Shared Neighborhood Hits	206
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.220545 (rank : 284)
Query Neighborhood Hits	453	Target Neighborhood Hits	342	Shared Neighborhood Hits	183
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD166_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.059671 (rank : 858)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	54
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

CD166_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.066608 (rank : 782)
Query Neighborhood Hits	453	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

CD22_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.088172 (rank : 620)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	60
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD22_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.095389 (rank : 590)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	57
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD276_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.052602 (rank : 918)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD320_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.077044 (rank : 712)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD97_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.174993 (rank : 373)
Query Neighborhood Hits	453	Target Neighborhood Hits	353	Shared Neighborhood Hits	172
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.145698 (rank : 419)
Query Neighborhood Hits	453	Target Neighborhood Hits	295	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CDON_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.203173 (rank : 326)
Query Neighborhood Hits	453	Target Neighborhood Hits	412	Shared Neighborhood Hits	111
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CDON_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.204557 (rank : 323)
Query Neighborhood Hits	453	Target Neighborhood Hits	410	Shared Neighborhood Hits	112
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CEA20_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.081482 (rank : 680)
Query Neighborhood Hits	453	Target Neighborhood Hits	251	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

CEAM1_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.071830 (rank : 756)
Query Neighborhood Hits	453	Target Neighborhood Hits	348	Shared Neighborhood Hits	62
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

CEAM1_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.080871 (rank : 686)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	64
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CEAM5_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.085561 (rank : 638)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	65
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

CEAM6_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.061461 (rank : 837)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	63
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

CEAM8_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.051217 (rank : 932)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

CFC1_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.194917 (rank : 343)
Query Neighborhood Hits	453	Target Neighborhood Hits	148	Shared Neighborhood Hits	124
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.180368 (rank : 364)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	108
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CI094_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.106821 (rank : 514)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.060189 (rank : 850)
Query Neighborhood Hits	453	Target Neighborhood Hits	266	Shared Neighborhood Hits	77
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.056015 (rank : 880)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	73
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP2_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.066949 (rank : 779)
Query Neighborhood Hits	453	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CLC14_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.059776 (rank : 857)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	66
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.061256 (rank : 841)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CNTN4_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.226574 (rank : 272)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN4_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.228608 (rank : 268)
Query Neighborhood Hits	453	Target Neighborhood Hits	445	Shared Neighborhood Hits	122
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN6_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.227384 (rank : 271)
Query Neighborhood Hits	453	Target Neighborhood Hits	422	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CNTN6_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.220767 (rank : 283)
Query Neighborhood Hits	453	Target Neighborhood Hits	429	Shared Neighborhood Hits	121
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

CNTP1_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.084077 (rank : 656)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.082676 (rank : 671)
Query Neighborhood Hits	453	Target Neighborhood Hits	183	Shared Neighborhood Hits	94
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.087538 (rank : 623)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.089147 (rank : 616)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	104
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.080247 (rank : 690)
Query Neighborhood Hits	453	Target Neighborhood Hits	195	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.080187 (rank : 691)
Query Neighborhood Hits	453	Target Neighborhood Hits	187	Shared Neighborhood Hits	91
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.083439 (rank : 666)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	107
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO1A1_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.059118 (rank : 862)
Query Neighborhood Hits	453	Target Neighborhood Hits	475	Shared Neighborhood Hits	44
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A1_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.052310 (rank : 923)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	40
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A2_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.059219 (rank : 861)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A2_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.063234 (rank : 817)
Query Neighborhood Hits	453	Target Neighborhood Hits	388	Shared Neighborhood Hits	19
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO2A1_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.062871 (rank : 824)
Query Neighborhood Hits	453	Target Neighborhood Hits	486	Shared Neighborhood Hits	17
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.062062 (rank : 832)
Query Neighborhood Hits	453	Target Neighborhood Hits	483	Shared Neighborhood Hits	27
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO3A1_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.052298 (rank : 924)
Query Neighborhood Hits	453	Target Neighborhood Hits	466	Shared Neighborhood Hits	32
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A1_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.069475 (rank : 762)
Query Neighborhood Hits	453	Target Neighborhood Hits	425	Shared Neighborhood Hits	19
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A1_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.069161 (rank : 764)
Query Neighborhood Hits	453	Target Neighborhood Hits	450	Shared Neighborhood Hits	18
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A2_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.069601 (rank : 761)
Query Neighborhood Hits	453	Target Neighborhood Hits	454	Shared Neighborhood Hits	17
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A2_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.066596 (rank : 783)
Query Neighborhood Hits	453	Target Neighborhood Hits	492	Shared Neighborhood Hits	23
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A3_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.073146 (rank : 744)
Query Neighborhood Hits	453	Target Neighborhood Hits	421	Shared Neighborhood Hits	23
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO4A4_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.075513 (rank : 724)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	22
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO4A5_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.055153 (rank : 891)
Query Neighborhood Hits	453	Target Neighborhood Hits	383	Shared Neighborhood Hits	19
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO4A6_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.066335 (rank : 786)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CO5A1_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.050195 (rank : 941)
Query Neighborhood Hits	453	Target Neighborhood Hits	434	Shared Neighborhood Hits	23
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO5A2_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.074381 (rank : 735)
Query Neighborhood Hits	453	Target Neighborhood Hits	760	Shared Neighborhood Hits	52
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO5A3_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.070361 (rank : 760)
Query Neighborhood Hits	453	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO6A1_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.072247 (rank : 752)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	14
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A1_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.062683 (rank : 827)
Query Neighborhood Hits	453	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A2_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.060025 (rank : 853)
Query Neighborhood Hits	453	Target Neighborhood Hits	249	Shared Neighborhood Hits	14
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO6A2_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.061520 (rank : 835)
Query Neighborhood Hits	453	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO6A3_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.096313 (rank : 582)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	27
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.083605 (rank : 663)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	121
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.059806 (rank : 855)
Query Neighborhood Hits	453	Target Neighborhood Hits	200	Shared Neighborhood Hits	90
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO9A1_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.075507 (rank : 725)
Query Neighborhood Hits	453	Target Neighborhood Hits	420	Shared Neighborhood Hits	22
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A1_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.073976 (rank : 739)
Query Neighborhood Hits	453	Target Neighborhood Hits	477	Shared Neighborhood Hits	18
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A2_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.072463 (rank : 748)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	13
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO9A2_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.072564 (rank : 747)
Query Neighborhood Hits	453	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO9A3_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.077398 (rank : 710)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	14
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CO9_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.058196 (rank : 869)
Query Neighborhood Hits	453	Target Neighborhood Hits	147	Shared Neighborhood Hits	74
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.060380 (rank : 849)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	78
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COAA1_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.063948 (rank : 810)
Query Neighborhood Hits	453	Target Neighborhood Hits	286	Shared Neighborhood Hits	19
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COBA1_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.068230 (rank : 769)
Query Neighborhood Hits	453	Target Neighborhood Hits	491	Shared Neighborhood Hits	27
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.069227 (rank : 763)
Query Neighborhood Hits	453	Target Neighborhood Hits	487	Shared Neighborhood Hits	24
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA2_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.068362 (rank : 768)
Query Neighborhood Hits	453	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COBA2_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.071851 (rank : 755)
Query Neighborhood Hits	453	Target Neighborhood Hits	501	Shared Neighborhood Hits	26
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COCH_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.099416 (rank : 558)
Query Neighborhood Hits	453	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COCH_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.098635 (rank : 570)
Query Neighborhood Hits	453	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COFA1_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.057603 (rank : 873)
Query Neighborhood Hits	453	Target Neighborhood Hits	305	Shared Neighborhood Hits	23
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

COGA1_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.084510 (rank : 651)
Query Neighborhood Hits	453	Target Neighborhood Hits	345	Shared Neighborhood Hits	34
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

COHA1_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.059778 (rank : 856)
Query Neighborhood Hits	453	Target Neighborhood Hits	414	Shared Neighborhood Hits	15
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COIA1_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.058585 (rank : 867)
Query Neighborhood Hits	453	Target Neighborhood Hits	447	Shared Neighborhood Hits	23
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COIA1_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.064050 (rank : 809)
Query Neighborhood Hits	453	Target Neighborhood Hits	481	Shared Neighborhood Hits	26
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COJA1_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.087722 (rank : 622)
Query Neighborhood Hits	453	Target Neighborhood Hits	323	Shared Neighborhood Hits	19
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

COLQ_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.066372 (rank : 785)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

COMP_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.183968 (rank : 357)
Query Neighborhood Hits	453	Target Neighborhood Hits	258	Shared Neighborhood Hits	170
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.199362 (rank : 338)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	182
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CONA1_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.085588 (rank : 637)
Query Neighborhood Hits	453	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CONA1_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.079769 (rank : 693)
Query Neighborhood Hits	453	Target Neighborhood Hits	254	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CRAC1_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.061015 (rank : 843)
Query Neighborhood Hits	453	Target Neighborhood Hits	111	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.062640 (rank : 828)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CREL1_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.273770 (rank : 197)
Query Neighborhood Hits	453	Target Neighborhood Hits	441	Shared Neighborhood Hits	197
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 579)	NC score	0.261302 (rank : 211)
Query Neighborhood Hits	453	Target Neighborhood Hits	524	Shared Neighborhood Hits	197
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.206358 (rank : 317)
Query Neighborhood Hits	453	Target Neighborhood Hits	362	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CSF1R_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.053541 (rank : 910)
Query Neighborhood Hits	453	Target Neighborhood Hits	983	Shared Neighborhood Hits	86
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSPG3_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.193913 (rank : 345)
Query Neighborhood Hits	453	Target Neighborhood Hits	676	Shared Neighborhood Hits	188
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CT075_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.119364 (rank : 471)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	69
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

CT127_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.101746 (rank : 546)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CTHR1_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.066798 (rank : 780)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.068589 (rank : 766)
Query Neighborhood Hits	453	Target Neighborhood Hits	123	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

CUBN_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.266647 (rank : 201)
Query Neighborhood Hits	453	Target Neighborhood Hits	477	Shared Neighborhood Hits	227
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CXAR_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.050679 (rank : 935)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	46
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

DKK3_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.054880 (rank : 898)
Query Neighborhood Hits	453	Target Neighborhood Hits	83	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

DUET_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.058024 (rank : 871)
Query Neighborhood Hits	453	Target Neighborhood Hits	1220	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

EGFL8_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.221025 (rank : 281)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	160
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.219620 (rank : 288)
Query Neighborhood Hits	453	Target Neighborhood Hits	266	Shared Neighborhood Hits	162
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGF_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.210215 (rank : 308)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	185
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

ELTD1_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.105859 (rank : 519)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.160580 (rank : 395)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	136
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMID1_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.055011 (rank : 895)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	12
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

EMR1_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.190784 (rank : 352)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	173
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.165237 (rank : 387)
Query Neighborhood Hits	453	Target Neighborhood Hits	349	Shared Neighborhood Hits	159
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.176210 (rank : 370)
Query Neighborhood Hits	453	Target Neighborhood Hits	345	Shared Neighborhood Hits	171
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.072308 (rank : 750)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.055269 (rank : 887)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	73
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

EPHA1_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.056804 (rank : 877)
Query Neighborhood Hits	453	Target Neighborhood Hits	958	Shared Neighborhood Hits	134
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA8_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.076105 (rank : 723)
Query Neighborhood Hits	453	Target Neighborhood Hits	956	Shared Neighborhood Hits	132
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.076356 (rank : 721)
Query Neighborhood Hits	453	Target Neighborhood Hits	969	Shared Neighborhood Hits	136
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

EPHB2_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.079215 (rank : 696)
Query Neighborhood Hits	453	Target Neighborhood Hits	983	Shared Neighborhood Hits	146
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.079068 (rank : 699)
Query Neighborhood Hits	453	Target Neighborhood Hits	982	Shared Neighborhood Hits	146
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EREG_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.054056 (rank : 906)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	45
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESAM_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.051296 (rank : 930)
Query Neighborhood Hits	453	Target Neighborhood Hits	251	Shared Neighborhood Hits	48
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ESM1_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.121423 (rank : 467)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.099085 (rank : 566)
Query Neighborhood Hits	453	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA10_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.103549 (rank : 532)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	166
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.102152 (rank : 543)
Query Neighborhood Hits	453	Target Neighborhood Hits	435	Shared Neighborhood Hits	168
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.111588 (rank : 498)
Query Neighborhood Hits	453	Target Neighborhood Hits	425	Shared Neighborhood Hits	157
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.086862 (rank : 626)
Query Neighborhood Hits	453	Target Neighborhood Hits	404	Shared Neighborhood Hits	154
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.072088 (rank : 754)
Query Neighborhood Hits	453	Target Neighborhood Hits	374	Shared Neighborhood Hits	131
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.094417 (rank : 595)
Query Neighborhood Hits	453	Target Neighborhood Hits	421	Shared Neighborhood Hits	159
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FAT2_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.108931 (rank : 506)
Query Neighborhood Hits	453	Target Neighborhood Hits	507	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FBLN2_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.246636 (rank : 232)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	188
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.242017 (rank : 238)
Query Neighborhood Hits	453	Target Neighborhood Hits	505	Shared Neighborhood Hits	204
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.199091 (rank : 339)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	167
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.192891 (rank : 348)
Query Neighborhood Hits	453	Target Neighborhood Hits	279	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.209781 (rank : 309)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	165
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.203293 (rank : 325)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	157
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.206273 (rank : 318)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	184
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.200632 (rank : 333)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	178
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FCRL2_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.090350 (rank : 609)
Query Neighborhood Hits	453	Target Neighborhood Hits	251	Shared Neighborhood Hits	54
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

FCRL5_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.089392 (rank : 615)
Query Neighborhood Hits	453	Target Neighborhood Hits	267	Shared Neighborhood Hits	54
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

FGFR1_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.058812 (rank : 865)
Query Neighborhood Hits	453	Target Neighborhood Hits	1069	Shared Neighborhood Hits	94
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.058848 (rank : 864)
Query Neighborhood Hits	453	Target Neighborhood Hits	1068	Shared Neighborhood Hits	94
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FGFR2_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.058336 (rank : 868)
Query Neighborhood Hits	453	Target Neighborhood Hits	1062	Shared Neighborhood Hits	94
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

FGFR2_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.055938 (rank : 882)
Query Neighborhood Hits	453	Target Neighborhood Hits	1062	Shared Neighborhood Hits	93
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

FGFR3_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.058747 (rank : 866)
Query Neighborhood Hits	453	Target Neighborhood Hits	1042	Shared Neighborhood Hits	94
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FGFR3_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.060498 (rank : 847)
Query Neighborhood Hits	453	Target Neighborhood Hits	1059	Shared Neighborhood Hits	97
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

FGFR4_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.061447 (rank : 839)
Query Neighborhood Hits	453	Target Neighborhood Hits	1037	Shared Neighborhood Hits	94
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FGFR4_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.063124 (rank : 820)
Query Neighborhood Hits	453	Target Neighborhood Hits	1026	Shared Neighborhood Hits	94
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FGRL1_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.132275 (rank : 441)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.131146 (rank : 442)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	69
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FRAS1_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.186314 (rank : 356)
Query Neighborhood Hits	453	Target Neighborhood Hits	747	Shared Neighborhood Hits	225
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FSTL3_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.073689 (rank : 742)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	86
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.067327 (rank : 777)
Query Neighborhood Hits	453	Target Neighborhood Hits	152	Shared Neighborhood Hits	84
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL4_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.103821 (rank : 529)
Query Neighborhood Hits	453	Target Neighborhood Hits	344	Shared Neighborhood Hits	75
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL4_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.104932 (rank : 524)
Query Neighborhood Hits	453	Target Neighborhood Hits	333	Shared Neighborhood Hits	76
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.103429 (rank : 533)
Query Neighborhood Hits	453	Target Neighborhood Hits	347	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.102822 (rank : 537)
Query Neighborhood Hits	453	Target Neighborhood Hits	355	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FST_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.061924 (rank : 834)
Query Neighborhood Hits	453	Target Neighborhood Hits	129	Shared Neighborhood Hits	53
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.062698 (rank : 826)
Query Neighborhood Hits	453	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GLDN_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.062085 (rank : 831)
Query Neighborhood Hits	453	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

GLDN_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.053120 (rank : 915)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

GPA33_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.060134 (rank : 851)
Query Neighborhood Hits	453	Target Neighborhood Hits	273	Shared Neighborhood Hits	51
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

GPA33_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.063877 (rank : 811)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

GRN_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.192323 (rank : 350)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	149
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.183658 (rank : 359)
Query Neighborhood Hits	453	Target Neighborhood Hits	248	Shared Neighborhood Hits	152
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HCFC1_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.053434 (rank : 911)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	58
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC1_MOUSE
θ value	θ > 10 (rank : 654)	NC score	0.057413 (rank : 874)
Query Neighborhood Hits	453	Target Neighborhood Hits	348	Shared Neighborhood Hits	62
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC2_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.120645 (rank : 469)
Query Neighborhood Hits	453	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HMCN1_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.227623 (rank : 270)
Query Neighborhood Hits	453	Target Neighborhood Hits	983	Shared Neighborhood Hits	270
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

I27RA_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.081450 (rank : 681)
Query Neighborhood Hits	453	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

I27RA_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.055063 (rank : 893)
Query Neighborhood Hits	453	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

IBP7_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.101026 (rank : 548)
Query Neighborhood Hits	453	Target Neighborhood Hits	220	Shared Neighborhood Hits	69
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.102297 (rank : 540)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	71
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ICAM5_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.102864 (rank : 536)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

ICAM5_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.106061 (rank : 516)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	67
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

IGF1R_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.056873 (rank : 876)
Query Neighborhood Hits	453	Target Neighborhood Hits	977	Shared Neighborhood Hits	156
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.056137 (rank : 879)
Query Neighborhood Hits	453	Target Neighborhood Hits	973	Shared Neighborhood Hits	159
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGS21_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.051395 (rank : 928)
Query Neighborhood Hits	453	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS21_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.050465 (rank : 938)
Query Neighborhood Hits	453	Target Neighborhood Hits	118	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS4B_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.083607 (rank : 662)
Query Neighborhood Hits	453	Target Neighborhood Hits	305	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

IGS4B_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.083685 (rank : 660)
Query Neighborhood Hits	453	Target Neighborhood Hits	328	Shared Neighborhood Hits	60
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IL1R2_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.065151 (rank : 800)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	44
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

IL1R2_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.056739 (rank : 878)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	40
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IL27B_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.118839 (rank : 476)
Query Neighborhood Hits	453	Target Neighborhood Hits	80	Shared Neighborhood Hits	56
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

INSRR_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.065321 (rank : 797)
Query Neighborhood Hits	453	Target Neighborhood Hits	950	Shared Neighborhood Hits	156
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 673)	NC score	0.065625 (rank : 794)
Query Neighborhood Hits	453	Target Neighborhood Hits	961	Shared Neighborhood Hits	160
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

IRPL1_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.050068 (rank : 942)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

IRPL1_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.054871 (rank : 899)
Query Neighborhood Hits	453	Target Neighborhood Hits	186	Shared Neighborhood Hits	53
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

IRPL2_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.055863 (rank : 883)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

IRPL2_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.055099 (rank : 892)
Query Neighborhood Hits	453	Target Neighborhood Hits	195	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

ITAX_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.050821 (rank : 934)
Query Neighborhood Hits	453	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXH4	Gene names	Itgax
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD11c antigen).

JAM1_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.094834 (rank : 593)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JAM1_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.091453 (rank : 606)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	61
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

JAM2_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.086184 (rank : 633)
Query Neighborhood Hits	453	Target Neighborhood Hits	304	Shared Neighborhood Hits	65
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM2_MOUSE
θ value	θ > 10 (rank : 682)	NC score	0.082275 (rank : 674)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM3_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.104369 (rank : 528)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAM3_MOUSE
θ value	θ > 10 (rank : 684)	NC score	0.100856 (rank : 549)
Query Neighborhood Hits	453	Target Neighborhood Hits	286	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

KALM_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.157103 (rank : 403)
Query Neighborhood Hits	453	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

KAZD1_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.119077 (rank : 474)
Query Neighborhood Hits	453	Target Neighborhood Hits	248	Shared Neighborhood Hits	75
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 687)	NC score	0.116528 (rank : 484)
Query Neighborhood Hits	453	Target Neighborhood Hits	281	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KIRR1_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.097232 (rank : 577)
Query Neighborhood Hits	453	Target Neighborhood Hits	401	Shared Neighborhood Hits	63
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR1_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.095827 (rank : 588)
Query Neighborhood Hits	453	Target Neighborhood Hits	403	Shared Neighborhood Hits	62
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR2_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.107614 (rank : 511)
Query Neighborhood Hits	453	Target Neighborhood Hits	321	Shared Neighborhood Hits	60
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

KIRR2_MOUSE
θ value	θ > 10 (rank : 691)	NC score	0.107249 (rank : 513)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

KIRR3_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.096014 (rank : 585)
Query Neighborhood Hits	453	Target Neighborhood Hits	302	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

KIRR3_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.094379 (rank : 596)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

KR105_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.239471 (rank : 247)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	156
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR10A_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.180052 (rank : 365)
Query Neighborhood Hits	453	Target Neighborhood Hits	232	Shared Neighborhood Hits	131
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR122_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.051885 (rank : 926)
Query Neighborhood Hits	453	Target Neighborhood Hits	97	Shared Neighborhood Hits	54
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR124_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.073262 (rank : 743)
Query Neighborhood Hits	453	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR410_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.138967 (rank : 427)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR413_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.118023 (rank : 480)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.209372 (rank : 310)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA13_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.235891 (rank : 254)
Query Neighborhood Hits	453	Target Neighborhood Hits	144	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.166745 (rank : 386)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.092775 (rank : 601)
Query Neighborhood Hits	453	Target Neighborhood Hits	192	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA63_HUMAN
θ value	θ > 10 (rank : 704)	NC score	0.060932 (rank : 845)
Query Neighborhood Hits	453	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

KRA93_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.228510 (rank : 269)
Query Neighborhood Hits	453	Target Neighborhood Hits	203	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA98_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.210281 (rank : 307)
Query Neighborhood Hits	453	Target Neighborhood Hits	185	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.213075 (rank : 302)
Query Neighborhood Hits	453	Target Neighborhood Hits	173	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LCE1A_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.129990 (rank : 445)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.155011 (rank : 407)
Query Neighborhood Hits	453	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.157898 (rank : 401)
Query Neighborhood Hits	453	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.134714 (rank : 435)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 712)	NC score	0.137460 (rank : 428)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.134632 (rank : 436)
Query Neighborhood Hits	453	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.061146 (rank : 842)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.059480 (rank : 860)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.067358 (rank : 776)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.063165 (rank : 819)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.119821 (rank : 470)
Query Neighborhood Hits	453	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE4A_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.082182 (rank : 676)
Query Neighborhood Hits	453	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LEPR_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.054738 (rank : 901)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	50
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

LEPR_MOUSE
θ value	θ > 10 (rank : 721)	NC score	0.050329 (rank : 939)
Query Neighborhood Hits	453	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

LIFR_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.167844 (rank : 383)
Query Neighborhood Hits	453	Target Neighborhood Hits	130	Shared Neighborhood Hits	81
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

LIFR_MOUSE
θ value	θ > 10 (rank : 723)	NC score	0.168073 (rank : 382)
Query Neighborhood Hits	453	Target Neighborhood Hits	127	Shared Neighborhood Hits	79
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

LORI_MOUSE
θ value	θ > 10 (rank : 724)	NC score	0.105900 (rank : 518)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRC21_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.085307 (rank : 641)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC21_MOUSE
θ value	θ > 10 (rank : 726)	NC score	0.085675 (rank : 635)
Query Neighborhood Hits	453	Target Neighborhood Hits	462	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC24_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.052607 (rank : 917)
Query Neighborhood Hits	453	Target Neighborhood Hits	404	Shared Neighborhood Hits	68
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRFN2_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.076402 (rank : 720)
Query Neighborhood Hits	453	Target Neighborhood Hits	450	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_MOUSE
θ value	θ > 10 (rank : 729)	NC score	0.076858 (rank : 714)
Query Neighborhood Hits	453	Target Neighborhood Hits	450	Shared Neighborhood Hits	80
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN3_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.073865 (rank : 741)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
θ value	θ > 10 (rank : 731)	NC score	0.078259 (rank : 707)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN4_MOUSE
θ value	θ > 10 (rank : 732)	NC score	0.080572 (rank : 687)
Query Neighborhood Hits	453	Target Neighborhood Hits	442	Shared Neighborhood Hits	81
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN5_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.063754 (rank : 813)
Query Neighborhood Hits	453	Target Neighborhood Hits	464	Shared Neighborhood Hits	74
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN5_MOUSE
θ value	θ > 10 (rank : 734)	NC score	0.065060 (rank : 801)
Query Neighborhood Hits	453	Target Neighborhood Hits	472	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRIG1_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.099857 (rank : 554)
Query Neighborhood Hits	453	Target Neighborhood Hits	654	Shared Neighborhood Hits	79
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
θ value	θ > 10 (rank : 736)	NC score	0.099401 (rank : 562)
Query Neighborhood Hits	453	Target Neighborhood Hits	627	Shared Neighborhood Hits	79
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.099413 (rank : 559)
Query Neighborhood Hits	453	Target Neighborhood Hits	595	Shared Neighborhood Hits	82
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
θ value	θ > 10 (rank : 738)	NC score	0.099498 (rank : 556)
Query Neighborhood Hits	453	Target Neighborhood Hits	586	Shared Neighborhood Hits	83
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG3_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.096736 (rank : 580)
Query Neighborhood Hits	453	Target Neighborhood Hits	601	Shared Neighborhood Hits	84
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRIG3_MOUSE
θ value	θ > 10 (rank : 740)	NC score	0.097380 (rank : 575)
Query Neighborhood Hits	453	Target Neighborhood Hits	611	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

LRP10_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.083931 (rank : 657)
Query Neighborhood Hits	453	Target Neighborhood Hits	197	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 742)	NC score	0.071095 (rank : 758)
Query Neighborhood Hits	453	Target Neighborhood Hits	169	Shared Neighborhood Hits	71
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.054968 (rank : 897)
Query Neighborhood Hits	453	Target Neighborhood Hits	205	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 744)	NC score	0.053857 (rank : 908)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.076614 (rank : 717)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	94
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP8_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.200240 (rank : 334)
Query Neighborhood Hits	453	Target Neighborhood Hits	346	Shared Neighborhood Hits	174
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRRN3_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.073921 (rank : 740)
Query Neighborhood Hits	453	Target Neighborhood Hits	461	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN3_MOUSE
θ value	θ > 10 (rank : 748)	NC score	0.067045 (rank : 778)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN5_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.057711 (rank : 872)
Query Neighborhood Hits	453	Target Neighborhood Hits	493	Shared Neighborhood Hits	76
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

LSAMP_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.108460 (rank : 509)
Query Neighborhood Hits	453	Target Neighborhood Hits	347	Shared Neighborhood Hits	66
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
θ value	θ > 10 (rank : 751)	NC score	0.109556 (rank : 505)
Query Neighborhood Hits	453	Target Neighborhood Hits	344	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

LTBP4_MOUSE
θ value	θ > 10 (rank : 752)	NC score	0.305107 (rank : 159)
Query Neighborhood Hits	453	Target Neighborhood Hits	607	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LU_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.099407 (rank : 561)
Query Neighborhood Hits	453	Target Neighborhood Hits	283	Shared Neighborhood Hits	65
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.119170 (rank : 473)
Query Neighborhood Hits	453	Target Neighborhood Hits	378	Shared Neighborhood Hits	156
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 755)	NC score	0.136273 (rank : 431)
Query Neighborhood Hits	453	Target Neighborhood Hits	390	Shared Neighborhood Hits	154
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MAG_HUMAN
θ value	θ > 10 (rank : 756)	NC score	0.104466 (rank : 526)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
θ value	θ > 10 (rank : 757)	NC score	0.104629 (rank : 525)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MALT1_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.117750 (rank : 482)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MAMC1_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.125167 (rank : 457)
Query Neighborhood Hits	453	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 760)	NC score	0.125873 (rank : 455)
Query Neighborhood Hits	453	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MARCO_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.054792 (rank : 900)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

MARCO_MOUSE
θ value	θ > 10 (rank : 762)	NC score	0.072712 (rank : 746)
Query Neighborhood Hits	453	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

MATN1_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.133736 (rank : 438)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	78
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 764)	NC score	0.133466 (rank : 439)
Query Neighborhood Hits	453	Target Neighborhood Hits	186	Shared Neighborhood Hits	75
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.250991 (rank : 226)
Query Neighborhood Hits	453	Target Neighborhood Hits	356	Shared Neighborhood Hits	170
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.216200 (rank : 296)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	135
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 767)	NC score	0.213724 (rank : 300)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	137
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.208606 (rank : 313)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	153
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 769)	NC score	0.200872 (rank : 331)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	149
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCSP_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.063211 (rank : 818)
Query Neighborhood Hits	453	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MDGA1_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.124061 (rank : 459)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MEGF9_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.322437 (rank : 138)
Query Neighborhood Hits	453	Target Neighborhood Hits	557	Shared Neighborhood Hits	240
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEP1A_HUMAN
θ value	θ > 10 (rank : 773)	NC score	0.060065 (rank : 852)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	84
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 774)	NC score	0.063552 (rank : 814)
Query Neighborhood Hits	453	Target Neighborhood Hits	166	Shared Neighborhood Hits	90
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MFA3L_HUMAN
θ value	θ > 10 (rank : 775)	NC score	0.083536 (rank : 664)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	62
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

MFA3L_MOUSE
θ value	θ > 10 (rank : 776)	NC score	0.074732 (rank : 730)
Query Neighborhood Hits	453	Target Neighborhood Hits	214	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

MFGM_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.073031 (rank : 745)
Query Neighborhood Hits	453	Target Neighborhood Hits	150	Shared Neighborhood Hits	86
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MKS3_HUMAN
θ value	θ > 10 (rank : 778)	NC score	0.067400 (rank : 775)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	58
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MKS3_MOUSE
θ value	θ > 10 (rank : 779)	NC score	0.076206 (rank : 722)
Query Neighborhood Hits	453	Target Neighborhood Hits	89	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MSRE_HUMAN
θ value	θ > 10 (rank : 780)	NC score	0.064671 (rank : 802)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

MT1A_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.077199 (rank : 711)
Query Neighborhood Hits	453	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.089141 (rank : 617)
Query Neighborhood Hits	453	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1E_HUMAN
θ value	θ > 10 (rank : 783)	NC score	0.054603 (rank : 902)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	42
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1F_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.054411 (rank : 904)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1H_HUMAN
θ value	θ > 10 (rank : 785)	NC score	0.073979 (rank : 738)
Query Neighborhood Hits	453	Target Neighborhood Hits	78	Shared Neighborhood Hits	42
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1L_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.052409 (rank : 922)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	38
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1M_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.053388 (rank : 912)
Query Neighborhood Hits	453	Target Neighborhood Hits	72	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MT1X_HUMAN
θ value	θ > 10 (rank : 788)	NC score	0.059523 (rank : 859)
Query Neighborhood Hits	453	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 789)	NC score	0.067445 (rank : 774)
Query Neighborhood Hits	453	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_MOUSE
θ value	θ > 10 (rank : 790)	NC score	0.090726 (rank : 608)
Query Neighborhood Hits	453	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.118574 (rank : 479)
Query Neighborhood Hits	453	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 792)	NC score	0.140250 (rank : 425)
Query Neighborhood Hits	453	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.092631 (rank : 603)
Query Neighborhood Hits	453	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 794)	NC score	0.128689 (rank : 447)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.075049 (rank : 729)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC18_HUMAN
θ value	θ > 10 (rank : 796)	NC score	0.105825 (rank : 520)
Query Neighborhood Hits	453	Target Neighborhood Hits	275	Shared Neighborhood Hits	63
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

MUC18_MOUSE
θ value	θ > 10 (rank : 797)	NC score	0.098620 (rank : 571)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

MUC2_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.096090 (rank : 584)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	153
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUSK_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.083452 (rank : 665)
Query Neighborhood Hits	453	Target Neighborhood Hits	1074	Shared Neighborhood Hits	95
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 800)	NC score	0.083886 (rank : 659)
Query Neighborhood Hits	453	Target Neighborhood Hits	1057	Shared Neighborhood Hits	95
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MYBPH_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.134940 (rank : 434)
Query Neighborhood Hits	453	Target Neighborhood Hits	256	Shared Neighborhood Hits	87
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYBPH_MOUSE
θ value	θ > 10 (rank : 802)	NC score	0.145487 (rank : 420)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	96
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYLK_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.067461 (rank : 773)
Query Neighborhood Hits	453	Target Neighborhood Hits	1328	Shared Neighborhood Hits	115
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYLK_MOUSE
θ value	θ > 10 (rank : 804)	NC score	0.067546 (rank : 772)
Query Neighborhood Hits	453	Target Neighborhood Hits	1489	Shared Neighborhood Hits	117
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYOM2_HUMAN
θ value	θ > 10 (rank : 805)	NC score	0.236551 (rank : 253)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	120
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

MYOTI_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.128318 (rank : 449)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYOTI_MOUSE
θ value	θ > 10 (rank : 807)	NC score	0.129461 (rank : 446)
Query Neighborhood Hits	453	Target Neighborhood Hits	297	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYPN_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.130354 (rank : 444)
Query Neighborhood Hits	453	Target Neighborhood Hits	418	Shared Neighborhood Hits	72
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYPN_MOUSE
θ value	θ > 10 (rank : 809)	NC score	0.128394 (rank : 448)
Query Neighborhood Hits	453	Target Neighborhood Hits	421	Shared Neighborhood Hits	70
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NCA12_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.147590 (rank : 415)
Query Neighborhood Hits	453	Target Neighborhood Hits	437	Shared Neighborhood Hits	102
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NCAM2_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.178023 (rank : 367)
Query Neighborhood Hits	453	Target Neighborhood Hits	441	Shared Neighborhood Hits	115
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

NCAM2_MOUSE
θ value	θ > 10 (rank : 812)	NC score	0.190675 (rank : 353)
Query Neighborhood Hits	453	Target Neighborhood Hits	472	Shared Neighborhood Hits	118
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NEGR1_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.109921 (rank : 503)
Query Neighborhood Hits	453	Target Neighborhood Hits	346	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

NEGR1_MOUSE
θ value	θ > 10 (rank : 814)	NC score	0.108510 (rank : 508)
Query Neighborhood Hits	453	Target Neighborhood Hits	349	Shared Neighborhood Hits	64
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

NET1_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.169919 (rank : 379)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	109
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 816)	NC score	0.167604 (rank : 384)
Query Neighborhood Hits	453	Target Neighborhood Hits	151	Shared Neighborhood Hits	107
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET4_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.191491 (rank : 351)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	134
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 818)	NC score	0.190671 (rank : 354)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	135
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NFX1_HUMAN
θ value	θ > 10 (rank : 819)	NC score	0.163838 (rank : 392)
Query Neighborhood Hits	453	Target Neighborhood Hits	405	Shared Neighborhood Hits	141
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.218010 (rank : 294)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	185
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_MOUSE
θ value	θ > 10 (rank : 821)	NC score	0.218080 (rank : 293)
Query Neighborhood Hits	453	Target Neighborhood Hits	338	Shared Neighborhood Hits	177
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NPTN_HUMAN
θ value	θ > 10 (rank : 822)	NC score	0.107947 (rank : 510)
Query Neighborhood Hits	453	Target Neighborhood Hits	212	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NPTN_MOUSE
θ value	θ > 10 (rank : 823)	NC score	0.101218 (rank : 547)
Query Neighborhood Hits	453	Target Neighborhood Hits	216	Shared Neighborhood Hits	61
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NRG1_HUMAN
θ value	θ > 10 (rank : 824)	NC score	0.121955 (rank : 465)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	124
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.136139 (rank : 432)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	141
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.148033 (rank : 413)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	157
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG4_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.072386 (rank : 749)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.066033 (rank : 790)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRX1A_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.106260 (rank : 515)
Query Neighborhood Hits	453	Target Neighborhood Hits	170	Shared Neighborhood Hits	99
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.105264 (rank : 522)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	98
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.103780 (rank : 531)
Query Neighborhood Hits	453	Target Neighborhood Hits	614	Shared Neighborhood Hits	119
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 832)	NC score	0.095808 (rank : 589)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NTRI_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.102904 (rank : 535)
Query Neighborhood Hits	453	Target Neighborhood Hits	344	Shared Neighborhood Hits	66
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NTRI_MOUSE
θ value	θ > 10 (rank : 834)	NC score	0.103803 (rank : 530)
Query Neighborhood Hits	453	Target Neighborhood Hits	342	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NTRK2_HUMAN
θ value	θ > 10 (rank : 835)	NC score	0.052478 (rank : 920)
Query Neighborhood Hits	453	Target Neighborhood Hits	1081	Shared Neighborhood Hits	104
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 836)	NC score	0.052030 (rank : 925)
Query Neighborhood Hits	453	Target Neighborhood Hits	1088	Shared Neighborhood Hits	104
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 837)	NC score	0.051736 (rank : 927)
Query Neighborhood Hits	453	Target Neighborhood Hits	1115	Shared Neighborhood Hits	104
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

OBSCN_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.072131 (rank : 753)
Query Neighborhood Hits	453	Target Neighborhood Hits	1931	Shared Neighborhood Hits	130
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OBSL1_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.144457 (rank : 421)
Query Neighborhood Hits	453	Target Neighborhood Hits	354	Shared Neighborhood Hits	68
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

OPCM_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.110226 (rank : 502)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	68
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

PCSK5_HUMAN
θ value	θ > 10 (rank : 841)	NC score	0.093153 (rank : 600)
Query Neighborhood Hits	453	Target Neighborhood Hits	291	Shared Neighborhood Hits	139
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK5_MOUSE
θ value	θ > 10 (rank : 842)	NC score	0.212694 (rank : 303)
Query Neighborhood Hits	453	Target Neighborhood Hits	613	Shared Neighborhood Hits	235
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
θ value	θ > 10 (rank : 843)	NC score	0.078982 (rank : 701)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	123
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PERT_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.074232 (rank : 736)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	91
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.062927 (rank : 823)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	86
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGCA_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.093678 (rank : 599)
Query Neighborhood Hits	453	Target Neighborhood Hits	821	Shared Neighborhood Hits	151
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCB_HUMAN
θ value	θ > 10 (rank : 847)	NC score	0.099236 (rank : 565)
Query Neighborhood Hits	453	Target Neighborhood Hits	478	Shared Neighborhood Hits	141
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 848)	NC score	0.106006 (rank : 517)
Query Neighborhood Hits	453	Target Neighborhood Hits	459	Shared Neighborhood Hits	144
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGH1_MOUSE
θ value	θ > 10 (rank : 849)	NC score	0.059915 (rank : 854)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 850)	NC score	0.064307 (rank : 806)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 851)	NC score	0.075153 (rank : 727)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PROS_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.231858 (rank : 264)
Query Neighborhood Hits	453	Target Neighborhood Hits	340	Shared Neighborhood Hits	199
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 853)	NC score	0.232024 (rank : 263)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	194
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.169761 (rank : 380)
Query Neighborhood Hits	453	Target Neighborhood Hits	422	Shared Neighborhood Hits	173
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 855)	NC score	0.172930 (rank : 376)
Query Neighborhood Hits	453	Target Neighborhood Hits	410	Shared Neighborhood Hits	169
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRPE_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.081097 (rank : 682)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PSG3_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.051309 (rank : 929)
Query Neighborhood Hits	453	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

PSG4_HUMAN
θ value	θ > 10 (rank : 858)	NC score	0.050296 (rank : 940)
Query Neighborhood Hits	453	Target Neighborhood Hits	243	Shared Neighborhood Hits	53
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PTK7_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.089664 (rank : 612)
Query Neighborhood Hits	453	Target Neighborhood Hits	1103	Shared Neighborhood Hits	95
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

PTN11_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.074516 (rank : 732)
Query Neighborhood Hits	453	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 861)	NC score	0.074481 (rank : 733)
Query Neighborhood Hits	453	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 862)	NC score	0.082073 (rank : 677)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 863)	NC score	0.081069 (rank : 683)
Query Neighborhood Hits	453	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN13_HUMAN
θ value	θ > 10 (rank : 864)	NC score	0.058163 (rank : 870)
Query Neighborhood Hits	453	Target Neighborhood Hits	471	Shared Neighborhood Hits	22
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	θ > 10 (rank : 865)	NC score	0.059116 (rank : 863)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	24
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN14_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.066676 (rank : 781)
Query Neighborhood Hits	453	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	θ > 10 (rank : 867)	NC score	0.065984 (rank : 792)
Query Neighborhood Hits	453	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN18_HUMAN
θ value	θ > 10 (rank : 868)	NC score	0.083437 (rank : 667)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 869)	NC score	0.084648 (rank : 648)
Query Neighborhood Hits	453	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 870)	NC score	0.085038 (rank : 645)
Query Neighborhood Hits	453	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 871)	NC score	0.084705 (rank : 647)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN21_HUMAN
θ value	θ > 10 (rank : 872)	NC score	0.065474 (rank : 796)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	θ > 10 (rank : 873)	NC score	0.066205 (rank : 788)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN22_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.083209 (rank : 668)
Query Neighborhood Hits	453	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 875)	NC score	0.080938 (rank : 684)
Query Neighborhood Hits	453	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.069126 (rank : 765)
Query Neighborhood Hits	453	Target Neighborhood Hits	646	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 877)	NC score	0.071206 (rank : 757)
Query Neighborhood Hits	453	Target Neighborhood Hits	726	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.085366 (rank : 640)
Query Neighborhood Hits	453	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 879)	NC score	0.085146 (rank : 642)
Query Neighborhood Hits	453	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN3_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.065249 (rank : 798)
Query Neighborhood Hits	453	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.063032 (rank : 822)
Query Neighborhood Hits	453	Target Neighborhood Hits	303	Shared Neighborhood Hits	21
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN5_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.084297 (rank : 653)
Query Neighborhood Hits	453	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 883)	NC score	0.084178 (rank : 654)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.076722 (rank : 715)
Query Neighborhood Hits	453	Target Neighborhood Hits	234	Shared Neighborhood Hits	18
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 885)	NC score	0.076540 (rank : 719)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 886)	NC score	0.086494 (rank : 629)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	17
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.086201 (rank : 632)
Query Neighborhood Hits	453	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.086281 (rank : 631)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	17
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 889)	NC score	0.086322 (rank : 630)
Query Neighborhood Hits	453	Target Neighborhood Hits	78	Shared Neighborhood Hits	17
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 890)	NC score	0.082190 (rank : 675)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	18
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 891)	NC score	0.082470 (rank : 673)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.099311 (rank : 564)
Query Neighborhood Hits	453	Target Neighborhood Hits	101	Shared Neighborhood Hits	19
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 893)	NC score	0.098872 (rank : 567)
Query Neighborhood Hits	453	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_HUMAN
θ value	θ > 10 (rank : 894)	NC score	0.099362 (rank : 563)
Query Neighborhood Hits	453	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 895)	NC score	0.099493 (rank : 557)
Query Neighborhood Hits	453	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRG_HUMAN
θ value	θ > 10 (rank : 896)	NC score	0.096405 (rank : 581)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	49
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 897)	NC score	0.095832 (rank : 587)
Query Neighborhood Hits	453	Target Neighborhood Hits	260	Shared Neighborhood Hits	48
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRK_MOUSE
θ value	θ > 10 (rank : 898)	NC score	0.170600 (rank : 377)
Query Neighborhood Hits	453	Target Neighborhood Hits	223	Shared Neighborhood Hits	102
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRN_HUMAN
θ value	θ > 10 (rank : 899)	NC score	0.082489 (rank : 672)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.081628 (rank : 679)
Query Neighborhood Hits	453	Target Neighborhood Hits	240	Shared Neighborhood Hits	27
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.084153 (rank : 655)
Query Neighborhood Hits	453	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 902)	NC score	0.083898 (rank : 658)
Query Neighborhood Hits	453	Target Neighborhood Hits	84	Shared Neighborhood Hits	18
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.105729 (rank : 521)
Query Neighborhood Hits	453	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

RAGE_HUMAN
θ value	θ > 10 (rank : 904)	NC score	0.102180 (rank : 542)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	64
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RAGE_MOUSE
θ value	θ > 10 (rank : 905)	NC score	0.102110 (rank : 544)
Query Neighborhood Hits	453	Target Neighborhood Hits	295	Shared Neighborhood Hits	65
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RECK_HUMAN
θ value	θ > 10 (rank : 906)	NC score	0.102487 (rank : 539)
Query Neighborhood Hits	453	Target Neighborhood Hits	189	Shared Neighborhood Hits	101
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 907)	NC score	0.078502 (rank : 702)
Query Neighborhood Hits	453	Target Neighborhood Hits	158	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RIMB2_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.125086 (rank : 458)
Query Neighborhood Hits	453	Target Neighborhood Hits	263	Shared Neighborhood Hits	52
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 909)	NC score	0.125393 (rank : 456)
Query Neighborhood Hits	453	Target Neighborhood Hits	246	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ROBO4_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.159568 (rank : 396)
Query Neighborhood Hits	453	Target Neighborhood Hits	364	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

ROBO4_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.157635 (rank : 402)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

ROR1_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.053156 (rank : 914)
Query Neighborhood Hits	453	Target Neighborhood Hits	1018	Shared Neighborhood Hits	102
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 913)	NC score	0.052706 (rank : 916)
Query Neighborhood Hits	453	Target Neighborhood Hits	1025	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.055020 (rank : 894)
Query Neighborhood Hits	453	Target Neighborhood Hits	1014	Shared Neighborhood Hits	101
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.056967 (rank : 875)
Query Neighborhood Hits	453	Target Neighborhood Hits	1000	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

SCUB3_MOUSE
θ value	θ > 10 (rank : 916)	NC score	0.241697 (rank : 243)
Query Neighborhood Hits	453	Target Neighborhood Hits	442	Shared Neighborhood Hits	221
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SFTPD_HUMAN
θ value	θ > 10 (rank : 917)	NC score	0.056000 (rank : 881)
Query Neighborhood Hits	453	Target Neighborhood Hits	238	Shared Neighborhood Hits	20
SwissProt Accessions	P35247, Q86YK9, Q9UCJ2, Q9UCJ3	Gene names	SFTPD, PSPD, SFTP4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SIG10_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.079004 (rank : 700)
Query Neighborhood Hits	453	Target Neighborhood Hits	363	Shared Neighborhood Hits	64
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

SIG11_HUMAN
θ value	θ > 10 (rank : 919)	NC score	0.079856 (rank : 692)
Query Neighborhood Hits	453	Target Neighborhood Hits	273	Shared Neighborhood Hits	64
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

SIGL5_MOUSE
θ value	θ > 10 (rank : 920)	NC score	0.063816 (rank : 812)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	56
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

SMDF_HUMAN
θ value	θ > 10 (rank : 921)	NC score	0.068462 (rank : 767)
Query Neighborhood Hits	453	Target Neighborhood Hits	117	Shared Neighborhood Hits	58
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SN_HUMAN
θ value	θ > 10 (rank : 922)	NC score	0.096770 (rank : 579)
Query Neighborhood Hits	453	Target Neighborhood Hits	434	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

SN_MOUSE
θ value	θ > 10 (rank : 923)	NC score	0.100833 (rank : 550)
Query Neighborhood Hits	453	Target Neighborhood Hits	416	Shared Neighborhood Hits	68
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

ST14_HUMAN
θ value	θ > 10 (rank : 924)	NC score	0.066137 (rank : 789)
Query Neighborhood Hits	453	Target Neighborhood Hits	409	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 925)	NC score	0.064269 (rank : 807)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	135
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TARSH_HUMAN
θ value	θ > 10 (rank : 926)	NC score	0.114346 (rank : 489)
Query Neighborhood Hits	453	Target Neighborhood Hits	768	Shared Neighborhood Hits	106
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TDGF1_HUMAN
θ value	θ > 10 (rank : 927)	NC score	0.126131 (rank : 453)
Query Neighborhood Hits	453	Target Neighborhood Hits	132	Shared Neighborhood Hits	100
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 928)	NC score	0.155860 (rank : 406)
Query Neighborhood Hits	453	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.123444 (rank : 461)
Query Neighborhood Hits	453	Target Neighborhood Hits	131	Shared Neighborhood Hits	99
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTA_HUMAN
θ value	θ > 10 (rank : 930)	NC score	0.054469 (rank : 903)
Query Neighborhood Hits	453	Target Neighborhood Hits	239	Shared Neighborhood Hits	117
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 931)	NC score	0.064308 (rank : 805)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	134
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.150471 (rank : 411)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 933)	NC score	0.150047 (rank : 412)
Query Neighborhood Hits	453	Target Neighborhood Hits	214	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TLL1_MOUSE
θ value	θ > 10 (rank : 934)	NC score	0.051056 (rank : 933)
Query Neighborhood Hits	453	Target Neighborhood Hits	237	Shared Neighborhood Hits	90
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TMIGD_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.104378 (rank : 527)
Query Neighborhood Hits	453	Target Neighborhood Hits	240	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TMIGD_MOUSE
θ value	θ > 10 (rank : 936)	NC score	0.103302 (rank : 534)
Query Neighborhood Hits	453	Target Neighborhood Hits	234	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TNR16_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.066015 (rank : 791)
Query Neighborhood Hits	453	Target Neighborhood Hits	183	Shared Neighborhood Hits	84
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 938)	NC score	0.055175 (rank : 890)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR25_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.065787 (rank : 793)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	65
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TSP2_HUMAN
θ value	θ > 10 (rank : 940)	NC score	0.122024 (rank : 464)
Query Neighborhood Hits	453	Target Neighborhood Hits	359	Shared Neighborhood Hits	169
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.158304 (rank : 399)
Query Neighborhood Hits	453	Target Neighborhood Hits	250	Shared Neighborhood Hits	146
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 942)	NC score	0.163887 (rank : 391)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	152
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 943)	NC score	0.202335 (rank : 327)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	172
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 944)	NC score	0.204359 (rank : 324)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UFO_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.074473 (rank : 734)
Query Neighborhood Hits	453	Target Neighborhood Hits	981	Shared Neighborhood Hits	117
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 946)	NC score	0.079706 (rank : 695)
Query Neighborhood Hits	453	Target Neighborhood Hits	988	Shared Neighborhood Hits	120
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

UNC5A_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.055626 (rank : 886)
Query Neighborhood Hits	453	Target Neighborhood Hits	198	Shared Neighborhood Hits	61
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 948)	NC score	0.050538 (rank : 937)
Query Neighborhood Hits	453	Target Neighborhood Hits	203	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.053907 (rank : 907)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 950)	NC score	0.053719 (rank : 909)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.055761 (rank : 884)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	68
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 952)	NC score	0.055683 (rank : 885)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 953)	NC score	0.062627 (rank : 829)
Query Neighborhood Hits	453	Target Neighborhood Hits	267	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 954)	NC score	0.065236 (rank : 799)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UROL1_MOUSE
θ value	θ > 10 (rank : 955)	NC score	0.088955 (rank : 618)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	102
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.239436 (rank : 248)
Query Neighborhood Hits	453	Target Neighborhood Hits	284	Shared Neighborhood Hits	173
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VCAM1_HUMAN
θ value	θ > 10 (rank : 957)	NC score	0.101877 (rank : 545)
Query Neighborhood Hits	453	Target Neighborhood Hits	352	Shared Neighborhood Hits	64
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

VCAM1_MOUSE
θ value	θ > 10 (rank : 958)	NC score	0.105034 (rank : 523)
Query Neighborhood Hits	453	Target Neighborhood Hits	320	Shared Neighborhood Hits	63
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

VGFR1_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.068184 (rank : 770)
Query Neighborhood Hits	453	Target Neighborhood Hits	1109	Shared Neighborhood Hits	93
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

VGFR1_MOUSE
θ value	θ > 10 (rank : 960)	NC score	0.068133 (rank : 771)
Query Neighborhood Hits	453	Target Neighborhood Hits	1118	Shared Neighborhood Hits	95
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

VGFR2_HUMAN
θ value	θ > 10 (rank : 961)	NC score	0.064572 (rank : 804)
Query Neighborhood Hits	453	Target Neighborhood Hits	1103	Shared Neighborhood Hits	93
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

VGFR2_MOUSE
θ value	θ > 10 (rank : 962)	NC score	0.063549 (rank : 815)
Query Neighborhood Hits	453	Target Neighborhood Hits	1089	Shared Neighborhood Hits	93
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

VGFR3_HUMAN
θ value	θ > 10 (rank : 963)	NC score	0.055252 (rank : 888)
Query Neighborhood Hits	453	Target Neighborhood Hits	1037	Shared Neighborhood Hits	93
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VGFR3_MOUSE
θ value	θ > 10 (rank : 964)	NC score	0.054287 (rank : 905)
Query Neighborhood Hits	453	Target Neighborhood Hits	1056	Shared Neighborhood Hits	96
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VITRN_HUMAN
θ value	θ > 10 (rank : 965)	NC score	0.098450 (rank : 572)
Query Neighborhood Hits	453	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

VITRN_MOUSE
θ value	θ > 10 (rank : 966)	NC score	0.097703 (rank : 573)
Query Neighborhood Hits	453	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

VSIG2_HUMAN
θ value	θ > 10 (rank : 967)	NC score	0.085051 (rank : 644)
Query Neighborhood Hits	453	Target Neighborhood Hits	321	Shared Neighborhood Hits	62
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG2_MOUSE
θ value	θ > 10 (rank : 968)	NC score	0.077551 (rank : 709)
Query Neighborhood Hits	453	Target Neighborhood Hits	316	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG4_HUMAN
θ value	θ > 10 (rank : 969)	NC score	0.066471 (rank : 784)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

WFDC3_HUMAN
θ value	θ > 10 (rank : 970)	NC score	0.097362 (rank : 576)
Query Neighborhood Hits	453	Target Neighborhood Hits	138	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ZAN_HUMAN
θ value	θ > 10 (rank : 971)	NC score	0.142748 (rank : 423)
Query Neighborhood Hits	453	Target Neighborhood Hits	679	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZNFX1_HUMAN
θ value	θ > 10 (rank : 972)	NC score	0.052600 (rank : 919)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	θ > 10 (rank : 973)	NC score	0.052444 (rank : 921)
Query Neighborhood Hits	453	Target Neighborhood Hits	407	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

TENN_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	453
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
NC score	0.981170 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	453	Target Neighborhood Hits	484	Shared Neighborhood Hits	392
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
NC score	0.956635 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	453	Target Neighborhood Hits	526	Shared Neighborhood Hits	392
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
NC score	0.954633 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	453	Target Neighborhood Hits	531	Shared Neighborhood Hits	391
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENA_MOUSE
NC score	0.878056 (rank : 5)	θ value	6.82227e-149 (rank : 6)
Query Neighborhood Hits	453	Target Neighborhood Hits	596	Shared Neighborhood Hits	402
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENA_HUMAN
NC score	0.871794 (rank : 6)	θ value	4.87785e-155 (rank : 5)
Query Neighborhood Hits	453	Target Neighborhood Hits	631	Shared Neighborhood Hits	410
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENX_HUMAN
NC score	0.868093 (rank : 7)	θ value	2.35568e-133 (rank : 7)
Query Neighborhood Hits	453	Target Neighborhood Hits	789	Shared Neighborhood Hits	410
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

MFAP4_MOUSE
NC score	0.722409 (rank : 8)	θ value	2.41655e-45 (rank : 19)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_HUMAN
NC score	0.722256 (rank : 9)	θ value	2.41655e-45 (rank : 18)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

FGL1_HUMAN
NC score	0.711082 (rank : 10)	θ value	1.85459e-37 (rank : 34)
Query Neighborhood Hits	453	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	Q08830, Q4PJH9, Q96KW6, Q96QM6	Gene names	FGL1, HFREP1
Domain Architecture
Description	Fibrinogen-like protein 1 precursor (Hepatocyte-derived fibrinogen- related protein 1) (HFREP-1) (Hepassocin) (HP-041).

ANGL7_MOUSE
NC score	0.710738 (rank : 11)	θ value	2.95404e-43 (rank : 21)
Query Neighborhood Hits	453	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

FCN3_HUMAN
NC score	0.710436 (rank : 12)	θ value	5.95217e-44 (rank : 20)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	48
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

ANGL7_HUMAN
NC score	0.710362 (rank : 13)	θ value	1.62093e-41 (rank : 24)
Query Neighborhood Hits	453	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

ANGL6_MOUSE
NC score	0.705340 (rank : 14)	θ value	1.08726e-37 (rank : 32)
Query Neighborhood Hits	453	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

ANGL5_HUMAN
NC score	0.703714 (rank : 15)	θ value	1.6813e-30 (rank : 44)
Query Neighborhood Hits	453	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

ANGL6_HUMAN
NC score	0.702647 (rank : 16)	θ value	1.08726e-37 (rank : 31)
Query Neighborhood Hits	453	Target Neighborhood Hits	70	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

FGL2_MOUSE
NC score	0.701019 (rank : 17)	θ value	3.16345e-37 (rank : 35)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	42
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

FCN2_HUMAN
NC score	0.699770 (rank : 18)	θ value	5.02714e-51 (rank : 13)
Query Neighborhood Hits	453	Target Neighborhood Hits	122	Shared Neighborhood Hits	46
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

FGL2_HUMAN
NC score	0.699091 (rank : 19)	θ value	1.73584e-35 (rank : 38)
Query Neighborhood Hits	453	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

FIBA_HUMAN
NC score	0.697420 (rank : 20)	θ value	6.37413e-38 (rank : 30)
Query Neighborhood Hits	453	Target Neighborhood Hits	132	Shared Neighborhood Hits	48
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

FIBB_MOUSE
NC score	0.695481 (rank : 21)	θ value	1.42001e-37 (rank : 33)
Query Neighborhood Hits	453	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

ANGL1_HUMAN
NC score	0.695013 (rank : 22)	θ value	1.91475e-42 (rank : 22)
Query Neighborhood Hits	453	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	O95841, Q5T5Z5	Gene names	ANGPTL1, ANG3, ANGPT3, ARP1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1) (Angiopoietin-3) (ANG-3).

FIBB_HUMAN
NC score	0.694887 (rank : 23)	θ value	2.19075e-38 (rank : 28)
Query Neighborhood Hits	453	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

ANGL1_MOUSE
NC score	0.694875 (rank : 24)	θ value	4.2656e-42 (rank : 23)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

ANGL2_MOUSE
NC score	0.694605 (rank : 25)	θ value	8.04462e-41 (rank : 25)
Query Neighborhood Hits	453	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL2_HUMAN
NC score	0.694334 (rank : 26)	θ value	1.05066e-40 (rank : 26)
Query Neighborhood Hits	453	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

FIBG_MOUSE
NC score	0.688136 (rank : 27)	θ value	1.98606e-31 (rank : 43)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VCM7, Q8WUR3, Q91ZP0	Gene names	Fgg
Domain Architecture	No domain graphic available
Description	Fibrinogen gamma chain precursor.

FCN1_HUMAN
NC score	0.687493 (rank : 28)	θ value	4.40402e-47 (rank : 16)
Query Neighborhood Hits	453	Target Neighborhood Hits	147	Shared Neighborhood Hits	47
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

ANGL4_HUMAN
NC score	0.687447 (rank : 29)	θ value	3.50572e-28 (rank : 47)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

ANGL4_MOUSE
NC score	0.687297 (rank : 30)	θ value	9.2256e-29 (rank : 45)
Query Neighborhood Hits	453	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

FIBG_HUMAN
NC score	0.686000 (rank : 31)	θ value	2.34606e-32 (rank : 42)
Query Neighborhood Hits	453	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	P02679, P04469, P04470, Q96A14, Q96KJ3	Gene names	FGG
Domain Architecture
Description	Fibrinogen gamma chain precursor.

ANGP4_HUMAN
NC score	0.683558 (rank : 32)	θ value	5.21438e-40 (rank : 27)
Query Neighborhood Hits	453	Target Neighborhood Hits	187	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

FCN1_MOUSE
NC score	0.678455 (rank : 33)	θ value	1.19655e-52 (rank : 12)
Query Neighborhood Hits	453	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

ANGP4_MOUSE
NC score	0.675722 (rank : 34)	θ value	3.73686e-38 (rank : 29)
Query Neighborhood Hits	453	Target Neighborhood Hits	220	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ANGP1_HUMAN
NC score	0.668611 (rank : 35)	θ value	1.73584e-35 (rank : 37)
Query Neighborhood Hits	453	Target Neighborhood Hits	254	Shared Neighborhood Hits	43
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP1_MOUSE
NC score	0.668188 (rank : 36)	θ value	2.96089e-35 (rank : 39)
Query Neighborhood Hits	453	Target Neighborhood Hits	252	Shared Neighborhood Hits	42
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGL3_MOUSE
NC score	0.648736 (rank : 37)	θ value	1.5242e-23 (rank : 51)
Query Neighborhood Hits	453	Target Neighborhood Hits	306	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ANGL3_HUMAN
NC score	0.646791 (rank : 38)	θ value	2.69047e-20 (rank : 54)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

ANGP2_HUMAN
NC score	0.645882 (rank : 39)	θ value	2.50655e-34 (rank : 41)
Query Neighborhood Hits	453	Target Neighborhood Hits	400	Shared Neighborhood Hits	47
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGP2_MOUSE
NC score	0.642452 (rank : 40)	θ value	6.59618e-35 (rank : 40)
Query Neighborhood Hits	453	Target Neighborhood Hits	397	Shared Neighborhood Hits	46
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

FINC_HUMAN
NC score	0.606604 (rank : 41)	θ value	1.07224e-85 (rank : 8)
Query Neighborhood Hits	453	Target Neighborhood Hits	302	Shared Neighborhood Hits	160
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.600589 (rank : 42)	θ value	5.50685e-82 (rank : 9)
Query Neighborhood Hits	453	Target Neighborhood Hits	309	Shared Neighborhood Hits	158
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

ITB4_HUMAN
NC score	0.527783 (rank : 43)	θ value	7.34386e-10 (rank : 92)
Query Neighborhood Hits	453	Target Neighborhood Hits	458	Shared Neighborhood Hits	300
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

WIF1_HUMAN
NC score	0.490254 (rank : 44)	θ value	7.58209e-15 (rank : 59)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	247
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
NC score	0.486980 (rank : 45)	θ value	6.41864e-14 (rank : 62)
Query Neighborhood Hits	453	Target Neighborhood Hits	393	Shared Neighborhood Hits	244
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

COCA1_MOUSE
NC score	0.481979 (rank : 46)	θ value	1.19377e-60 (rank : 10)
Query Neighborhood Hits	453	Target Neighborhood Hits	467	Shared Neighborhood Hits	137
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_HUMAN
NC score	0.477050 (rank : 47)	θ value	2.65945e-60 (rank : 11)
Query Neighborhood Hits	453	Target Neighborhood Hits	458	Shared Neighborhood Hits	132
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

NAGPA_HUMAN
NC score	0.472215 (rank : 48)	θ value	9.59137e-10 (rank : 93)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	208
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

USH2A_MOUSE
NC score	0.468338 (rank : 49)	θ value	2.98157e-11 (rank : 79)
Query Neighborhood Hits	453	Target Neighborhood Hits	626	Shared Neighborhood Hits	319
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

NAGPA_MOUSE
NC score	0.467519 (rank : 50)	θ value	1.02475e-11 (rank : 74)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

USH2A_HUMAN
NC score	0.461393 (rank : 51)	θ value	2.13673e-09 (rank : 95)
Query Neighborhood Hits	453	Target Neighborhood Hits	600	Shared Neighborhood Hits	315
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

COEA1_MOUSE
NC score	0.445137 (rank : 52)	θ value	2.75849e-49 (rank : 15)
Query Neighborhood Hits	453	Target Neighborhood Hits	402	Shared Neighborhood Hits	107
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

SREC2_HUMAN
NC score	0.441826 (rank : 53)	θ value	3.08544e-08 (rank : 108)
Query Neighborhood Hits	453	Target Neighborhood Hits	645	Shared Neighborhood Hits	263
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
NC score	0.441136 (rank : 54)	θ value	3.08544e-08 (rank : 109)
Query Neighborhood Hits	453	Target Neighborhood Hits	605	Shared Neighborhood Hits	255
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
NC score	0.429463 (rank : 55)	θ value	5.62301e-10 (rank : 91)
Query Neighborhood Hits	453	Target Neighborhood Hits	645	Shared Neighborhood Hits	271
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

COEA1_HUMAN
NC score	0.427329 (rank : 56)	θ value	1.91031e-50 (rank : 14)
Query Neighborhood Hits	453	Target Neighborhood Hits	427	Shared Neighborhood Hits	115
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

ITB6_MOUSE
NC score	0.424293 (rank : 57)	θ value	3.89403e-11 (rank : 80)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	214
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_HUMAN
NC score	0.424256 (rank : 58)	θ value	7.84624e-12 (rank : 71)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	210
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB5_MOUSE
NC score	0.422848 (rank : 59)	θ value	4.02038e-16 (rank : 56)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	216
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB3_HUMAN
NC score	0.420665 (rank : 60)	θ value	2.98157e-11 (rank : 78)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	216
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB5_HUMAN
NC score	0.417276 (rank : 61)	θ value	5.8054e-15 (rank : 58)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	211
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB3_MOUSE
NC score	0.417133 (rank : 62)	θ value	1.9326e-10 (rank : 85)
Query Neighborhood Hits	453	Target Neighborhood Hits	319	Shared Neighborhood Hits	207
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB7_HUMAN
NC score	0.416501 (rank : 63)	θ value	1.86753e-13 (rank : 63)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	197
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB2_MOUSE
NC score	0.416391 (rank : 64)	θ value	2.79066e-09 (rank : 97)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	224
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

DLK_HUMAN
NC score	0.416306 (rank : 65)	θ value	1.17247e-07 (rank : 118)
Query Neighborhood Hits	453	Target Neighborhood Hits	401	Shared Neighborhood Hits	243
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

KRA58_HUMAN
NC score	0.415411 (rank : 66)	θ value	0.000270298 (rank : 174)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	183
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KR171_HUMAN
NC score	0.415101 (rank : 67)	θ value	0.0113563 (rank : 217)
Query Neighborhood Hits	453	Target Neighborhood Hits	144	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

EGFL9_HUMAN
NC score	0.413826 (rank : 68)	θ value	6.21693e-09 (rank : 102)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	238
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

ITB2_HUMAN
NC score	0.413392 (rank : 69)	θ value	2.79066e-09 (rank : 96)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	197
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB7_MOUSE
NC score	0.412977 (rank : 70)	θ value	2.43908e-13 (rank : 64)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	200
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

EGFL9_MOUSE
NC score	0.411400 (rank : 71)	θ value	6.87365e-08 (rank : 111)
Query Neighborhood Hits	453	Target Neighborhood Hits	379	Shared Neighborhood Hits	241
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

KRA53_HUMAN
NC score	0.410333 (rank : 72)	θ value	0.0193708 (rank : 229)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	189
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

DLK_MOUSE
NC score	0.409742 (rank : 73)	θ value	9.92553e-07 (rank : 130)
Query Neighborhood Hits	453	Target Neighborhood Hits	374	Shared Neighborhood Hits	233
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

KRA51_HUMAN
NC score	0.409466 (rank : 74)	θ value	0.0252991 (rank : 234)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	166
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

COKA1_HUMAN
NC score	0.409205 (rank : 75)	θ value	1.24688e-25 (rank : 49)
Query Neighborhood Hits	453	Target Neighborhood Hits	403	Shared Neighborhood Hits	109
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

KRA57_HUMAN
NC score	0.404022 (rank : 76)	θ value	0.00390308 (rank : 202)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	163
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

ITB1_HUMAN
NC score	0.403695 (rank : 77)	θ value	1.02475e-11 (rank : 73)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	191
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB8_HUMAN
NC score	0.403571 (rank : 78)	θ value	3.89403e-11 (rank : 81)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	189
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

ITB1_MOUSE
NC score	0.403521 (rank : 79)	θ value	5.62301e-10 (rank : 89)
Query Neighborhood Hits	453	Target Neighborhood Hits	283	Shared Neighborhood Hits	186
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

JAG1_MOUSE
NC score	0.402783 (rank : 80)	θ value	2.88788e-06 (rank : 131)
Query Neighborhood Hits	453	Target Neighborhood Hits	518	Shared Neighborhood Hits	263
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
NC score	0.402743 (rank : 81)	θ value	3.41135e-07 (rank : 121)
Query Neighborhood Hits	453	Target Neighborhood Hits	514	Shared Neighborhood Hits	261
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

FNDC3_MOUSE
NC score	0.402380 (rank : 82)	θ value	3.29651e-10 (rank : 87)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	131
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

DLL4_MOUSE
NC score	0.400458 (rank : 83)	θ value	0.000121331 (rank : 164)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	249
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_HUMAN
NC score	0.400386 (rank : 84)	θ value	8.40245e-06 (rank : 143)
Query Neighborhood Hits	453	Target Neighborhood Hits	435	Shared Neighborhood Hits	243
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL3_HUMAN
NC score	0.400233 (rank : 85)	θ value	2.61198e-07 (rank : 119)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	236
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

JAG2_MOUSE
NC score	0.397278 (rank : 86)	θ value	3.41135e-07 (rank : 122)
Query Neighborhood Hits	453	Target Neighborhood Hits	504	Shared Neighborhood Hits	259
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

JAG2_HUMAN
NC score	0.396479 (rank : 87)	θ value	2.61198e-07 (rank : 120)
Query Neighborhood Hits	453	Target Neighborhood Hits	491	Shared Neighborhood Hits	256
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

DLL3_MOUSE
NC score	0.396320 (rank : 88)	θ value	8.97725e-08 (rank : 114)
Query Neighborhood Hits	453	Target Neighborhood Hits	399	Shared Neighborhood Hits	233
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

MEGF6_HUMAN
NC score	0.395704 (rank : 89)	θ value	2.0648e-12 (rank : 66)
Query Neighborhood Hits	453	Target Neighborhood Hits	671	Shared Neighborhood Hits	281
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

DNER_HUMAN
NC score	0.393399 (rank : 90)	θ value	1.38499e-08 (rank : 104)
Query Neighborhood Hits	453	Target Neighborhood Hits	460	Shared Neighborhood Hits	239
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
NC score	0.392967 (rank : 91)	θ value	3.08544e-08 (rank : 107)
Query Neighborhood Hits	453	Target Neighborhood Hits	413	Shared Neighborhood Hits	236
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLL1_HUMAN
NC score	0.391881 (rank : 92)	θ value	3.77169e-06 (rank : 132)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	254
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
NC score	0.391789 (rank : 93)	θ value	3.77169e-06 (rank : 133)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	259
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

FNDC3_HUMAN
NC score	0.388050 (rank : 94)	θ value	0.000158464 (rank : 168)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

KRA59_HUMAN
NC score	0.385602 (rank : 95)	θ value	0.21417 (rank : 295)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	166
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

STAB1_MOUSE
NC score	0.377194 (rank : 96)	θ value	2.79066e-09 (rank : 98)
Query Neighborhood Hits	453	Target Neighborhood Hits	566	Shared Neighborhood Hits	272
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
NC score	0.375849 (rank : 97)	θ value	6.87365e-08 (rank : 113)
Query Neighborhood Hits	453	Target Neighborhood Hits	534	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB1_HUMAN
NC score	0.373824 (rank : 98)	θ value	3.29651e-10 (rank : 88)
Query Neighborhood Hits	453	Target Neighborhood Hits	546	Shared Neighborhood Hits	270
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_MOUSE
NC score	0.373023 (rank : 99)	θ value	5.81887e-07 (rank : 129)
Query Neighborhood Hits	453	Target Neighborhood Hits	528	Shared Neighborhood Hits	271
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CRUM1_HUMAN
NC score	0.372264 (rank : 100)	θ value	0.000158464 (rank : 167)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	244
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
NC score	0.371629 (rank : 101)	θ value	6.43352e-06 (rank : 138)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	238
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

KRA54_HUMAN
NC score	0.371001 (rank : 102)	θ value	0.0961366 (rank : 265)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	157
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA56_HUMAN
NC score	0.370053 (rank : 103)	θ value	0.21417 (rank : 294)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	130
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

CRUM2_HUMAN
NC score	0.367212 (rank : 104)	θ value	4.92598e-06 (rank : 137)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	243
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

HHIP_HUMAN
NC score	0.366367 (rank : 105)	θ value	0.00035302 (rank : 177)
Query Neighborhood Hits	453	Target Neighborhood Hits	249	Shared Neighborhood Hits	196
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

NOTC1_MOUSE
NC score	0.360155 (rank : 106)	θ value	8.97725e-08 (rank : 115)
Query Neighborhood Hits	453	Target Neighborhood Hits	916	Shared Neighborhood Hits	268
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KRA55_HUMAN
NC score	0.360147 (rank : 107)	θ value	1.06291 (rank : 355)
Query Neighborhood Hits	453	Target Neighborhood Hits	257	Shared Neighborhood Hits	152
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

HHIP_MOUSE
NC score	0.357528 (rank : 108)	θ value	0.000786445 (rank : 186)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	176
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

NOTC1_HUMAN
NC score	0.355335 (rank : 109)	θ value	1.63604e-09 (rank : 94)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	269
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
NC score	0.351912 (rank : 110)	θ value	6.87365e-08 (rank : 112)
Query Neighborhood Hits	453	Target Neighborhood Hits	1062	Shared Neighborhood Hits	277
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
NC score	0.351866 (rank : 111)	θ value	3.64472e-09 (rank : 99)
Query Neighborhood Hits	453	Target Neighborhood Hits	975	Shared Neighborhood Hits	275
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_MOUSE
NC score	0.350554 (rank : 112)	θ value	3.41135e-07 (rank : 124)
Query Neighborhood Hits	453	Target Neighborhood Hits	1069	Shared Neighborhood Hits	275
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.350177 (rank : 113)	θ value	3.41135e-07 (rank : 123)
Query Neighborhood Hits	453	Target Neighborhood Hits	1113	Shared Neighborhood Hits	281
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CO7A1_HUMAN
NC score	0.348877 (rank : 114)	θ value	6.35935e-46 (rank : 17)
Query Neighborhood Hits	453	Target Neighborhood Hits	807	Shared Neighborhood Hits	151
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

KR511_HUMAN
NC score	0.347107 (rank : 115)	θ value	1.38821 (rank : 365)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	131
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

NOTC4_HUMAN
NC score	0.345875 (rank : 116)	θ value	3.89403e-11 (rank : 82)
Query Neighborhood Hits	453	Target Neighborhood Hits	905	Shared Neighborhood Hits	277
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

PTPRB_HUMAN
NC score	0.344452 (rank : 117)	θ value	1.01765e-35 (rank : 36)
Query Neighborhood Hits	453	Target Neighborhood Hits	242	Shared Neighborhood Hits	85
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

SDK2_MOUSE
NC score	0.342928 (rank : 118)	θ value	1.9326e-10 (rank : 86)
Query Neighborhood Hits	453	Target Neighborhood Hits	480	Shared Neighborhood Hits	143
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

NOTC4_MOUSE
NC score	0.342076 (rank : 119)	θ value	1.80886e-08 (rank : 105)
Query Neighborhood Hits	453	Target Neighborhood Hits	872	Shared Neighborhood Hits	273
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PTPRD_HUMAN
NC score	0.339630 (rank : 120)	θ value	1.92365e-26 (rank : 48)
Query Neighborhood Hits	453	Target Neighborhood Hits	485	Shared Neighborhood Hits	143
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

LAMA5_MOUSE
NC score	0.338814 (rank : 121)	θ value	1.09739e-05 (rank : 145)
Query Neighborhood Hits	453	Target Neighborhood Hits	828	Shared Neighborhood Hits	262
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

SDK2_HUMAN
NC score	0.337193 (rank : 122)	θ value	4.76016e-09 (rank : 101)
Query Neighborhood Hits	453	Target Neighborhood Hits	495	Shared Neighborhood Hits	141
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

PTPRD_MOUSE
NC score	0.336956 (rank : 123)	θ value	1.99067e-23 (rank : 52)
Query Neighborhood Hits	453	Target Neighborhood Hits	491	Shared Neighborhood Hits	141
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

NEO1_MOUSE
NC score	0.335975 (rank : 124)	θ value	3.18553e-13 (rank : 65)
Query Neighborhood Hits	453	Target Neighborhood Hits	523	Shared Neighborhood Hits	140
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

FBN2_HUMAN
NC score	0.335257 (rank : 125)	θ value	1.33837e-11 (rank : 76)
Query Neighborhood Hits	453	Target Neighborhood Hits	560	Shared Neighborhood Hits	273
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

KRA52_HUMAN
NC score	0.335218 (rank : 126)	θ value	0.279714 (rank : 310)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	140
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

NEO1_HUMAN
NC score	0.333788 (rank : 127)	θ value	6.41864e-14 (rank : 61)
Query Neighborhood Hits	453	Target Neighborhood Hits	530	Shared Neighborhood Hits	140
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

MEGF8_HUMAN
NC score	0.333516 (rank : 128)	θ value	1.09739e-05 (rank : 146)
Query Neighborhood Hits	453	Target Neighborhood Hits	528	Shared Neighborhood Hits	244
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMA5_HUMAN
NC score	0.333470 (rank : 129)	θ value	5.81887e-07 (rank : 128)
Query Neighborhood Hits	453	Target Neighborhood Hits	976	Shared Neighborhood Hits	266
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FBN2_MOUSE
NC score	0.332370 (rank : 130)	θ value	7.84624e-12 (rank : 70)
Query Neighborhood Hits	453	Target Neighborhood Hits	549	Shared Neighborhood Hits	269
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.331858 (rank : 131)	θ value	1.02475e-11 (rank : 72)
Query Neighborhood Hits	453	Target Neighborhood Hits	563	Shared Neighborhood Hits	275
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN3_HUMAN
NC score	0.331074 (rank : 132)	θ value	6.00763e-12 (rank : 69)
Query Neighborhood Hits	453	Target Neighborhood Hits	543	Shared Neighborhood Hits	264
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

SDK1_HUMAN
NC score	0.330467 (rank : 133)	θ value	1.80886e-08 (rank : 106)
Query Neighborhood Hits	453	Target Neighborhood Hits	511	Shared Neighborhood Hits	141
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
NC score	0.330109 (rank : 134)	θ value	3.41135e-07 (rank : 125)
Query Neighborhood Hits	453	Target Neighborhood Hits	495	Shared Neighborhood Hits	142
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

FBN1_HUMAN
NC score	0.329966 (rank : 135)	θ value	1.74796e-11 (rank : 77)
Query Neighborhood Hits	453	Target Neighborhood Hits	557	Shared Neighborhood Hits	274
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

PTPRF_HUMAN
NC score	0.326476 (rank : 136)	θ value	8.93572e-24 (rank : 50)
Query Neighborhood Hits	453	Target Neighborhood Hits	489	Shared Neighborhood Hits	141
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

MEGF8_MOUSE
NC score	0.326128 (rank : 137)	θ value	1.87187e-05 (rank : 149)
Query Neighborhood Hits	453	Target Neighborhood Hits	520	Shared Neighborhood Hits	241
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
NC score	0.322437 (rank : 138)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	453	Target Neighborhood Hits	557	Shared Neighborhood Hits	240
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PTPRS_HUMAN
NC score	0.321323 (rank : 139)	θ value	4.74913e-17 (rank : 55)
Query Neighborhood Hits	453	Target Neighborhood Hits	472	Shared Neighborhood Hits	140
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

KR104_HUMAN
NC score	0.318160 (rank : 140)	θ value	0.62314 (rank : 323)
Query Neighborhood Hits	453	Target Neighborhood Hits	313	Shared Neighborhood Hits	177
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

DCC_HUMAN
NC score	0.316538 (rank : 141)	θ value	8.67504e-11 (rank : 84)
Query Neighborhood Hits	453	Target Neighborhood Hits	583	Shared Neighborhood Hits	141
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

AGRIN_HUMAN
NC score	0.313979 (rank : 142)	θ value	0.21417 (rank : 289)
Query Neighborhood Hits	453	Target Neighborhood Hits	582	Shared Neighborhood Hits	260
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

LTBP2_HUMAN
NC score	0.313604 (rank : 143)	θ value	3.19293e-05 (rank : 154)
Query Neighborhood Hits	453	Target Neighborhood Hits	552	Shared Neighborhood Hits	265
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LAMA1_MOUSE
NC score	0.313505 (rank : 144)	θ value	1.43324e-05 (rank : 148)
Query Neighborhood Hits	453	Target Neighborhood Hits	838	Shared Neighborhood Hits	256
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_HUMAN
NC score	0.312453 (rank : 145)	θ value	0.00228821 (rank : 197)
Query Neighborhood Hits	453	Target Neighborhood Hits	692	Shared Neighborhood Hits	230
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
NC score	0.311871 (rank : 146)	θ value	0.00134147 (rank : 192)
Query Neighborhood Hits	453	Target Neighborhood Hits	722	Shared Neighborhood Hits	228
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LTBP2_MOUSE
NC score	0.310449 (rank : 147)	θ value	0.00134147 (rank : 193)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	255
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KR107_HUMAN
NC score	0.310202 (rank : 148)	θ value	0.21417 (rank : 293)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	192
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

DCC_MOUSE
NC score	0.309236 (rank : 149)	θ value	6.64225e-11 (rank : 83)
Query Neighborhood Hits	453	Target Neighborhood Hits	896	Shared Neighborhood Hits	146
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

LRP1B_MOUSE
NC score	0.309221 (rank : 150)	θ value	5.62301e-10 (rank : 90)
Query Neighborhood Hits	453	Target Neighborhood Hits	606	Shared Neighborhood Hits	276
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
NC score	0.308988 (rank : 151)	θ value	4.0297e-08 (rank : 110)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	278
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_HUMAN
NC score	0.308704 (rank : 152)	θ value	1.06045e-08 (rank : 103)
Query Neighborhood Hits	453	Target Neighborhood Hits	602	Shared Neighborhood Hits	276
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LAMB3_MOUSE
NC score	0.308153 (rank : 153)	θ value	0.00102713 (rank : 188)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	192
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

KR106_HUMAN
NC score	0.307752 (rank : 154)	θ value	2.36792 (rank : 378)
Query Neighborhood Hits	453	Target Neighborhood Hits	347	Shared Neighborhood Hits	194
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR510_HUMAN
NC score	0.307104 (rank : 155)	θ value	3.0926 (rank : 397)
Query Neighborhood Hits	453	Target Neighborhood Hits	217	Shared Neighborhood Hits	128
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

NELL2_HUMAN
NC score	0.306899 (rank : 156)	θ value	0.163984 (rank : 283)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	243
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
NC score	0.305732 (rank : 157)	θ value	0.62314 (rank : 326)
Query Neighborhood Hits	453	Target Neighborhood Hits	436	Shared Neighborhood Hits	241
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

LAMC3_MOUSE
NC score	0.305440 (rank : 158)	θ value	0.00509761 (rank : 205)
Query Neighborhood Hits	453	Target Neighborhood Hits	624	Shared Neighborhood Hits	234
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LTBP4_MOUSE
NC score	0.305107 (rank : 159)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	453	Target Neighborhood Hits	607	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LAMA1_HUMAN
NC score	0.304941 (rank : 160)	θ value	4.1701e-05 (rank : 158)
Query Neighborhood Hits	453	Target Neighborhood Hits	804	Shared Neighborhood Hits	246
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

PGBM_MOUSE
NC score	0.304741 (rank : 161)	θ value	0.0563607 (rank : 254)
Query Neighborhood Hits	453	Target Neighborhood Hits	1073	Shared Neighborhood Hits	324
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MEGF9_MOUSE
NC score	0.304715 (rank : 162)	θ value	4.03905 (rank : 414)
Query Neighborhood Hits	453	Target Neighborhood Hits	896	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PGBM_HUMAN
NC score	0.302670 (rank : 163)	θ value	0.00509761 (rank : 207)
Query Neighborhood Hits	453	Target Neighborhood Hits	1113	Shared Neighborhood Hits	318
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NELL1_HUMAN
NC score	0.301960 (rank : 164)	θ value	0.0961366 (rank : 267)
Query Neighborhood Hits	453	Target Neighborhood Hits	451	Shared Neighborhood Hits	237
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LAMC3_HUMAN
NC score	0.300946 (rank : 165)	θ value	0.0330416 (rank : 241)
Query Neighborhood Hits	453	Target Neighborhood Hits	588	Shared Neighborhood Hits	243
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMB1_MOUSE
NC score	0.299913 (rank : 166)	θ value	0.00869519 (rank : 212)
Query Neighborhood Hits	453	Target Neighborhood Hits	919	Shared Neighborhood Hits	228
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NRCAM_HUMAN
NC score	0.299377 (rank : 167)	θ value	3.77169e-06 (rank : 134)
Query Neighborhood Hits	453	Target Neighborhood Hits	439	Shared Neighborhood Hits	131
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

PTPRV_MOUSE
NC score	0.296577 (rank : 168)	θ value	1.2049e-28 (rank : 46)
Query Neighborhood Hits	453	Target Neighborhood Hits	179	Shared Neighborhood Hits	73
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

LAMB3_HUMAN
NC score	0.295341 (rank : 169)	θ value	0.0113563 (rank : 218)
Query Neighborhood Hits	453	Target Neighborhood Hits	461	Shared Neighborhood Hits	178
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

SORL_MOUSE
NC score	0.295191 (rank : 170)	θ value	0.000461057 (rank : 180)
Query Neighborhood Hits	453	Target Neighborhood Hits	439	Shared Neighborhood Hits	265
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LTB1L_MOUSE
NC score	0.293590 (rank : 171)	θ value	0.0148317 (rank : 224)
Query Neighborhood Hits	453	Target Neighborhood Hits	514	Shared Neighborhood Hits	244
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.292682 (rank : 172)	θ value	0.0148317 (rank : 225)
Query Neighborhood Hits	453	Target Neighborhood Hits	479	Shared Neighborhood Hits	233
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.292409 (rank : 173)	θ value	0.125558 (rank : 274)
Query Neighborhood Hits	453	Target Neighborhood Hits	553	Shared Neighborhood Hits	243
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.291594 (rank : 174)	θ value	0.125558 (rank : 275)
Query Neighborhood Hits	453	Target Neighborhood Hits	502	Shared Neighborhood Hits	233
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DSCL1_HUMAN
NC score	0.290741 (rank : 175)	θ value	6.43352e-06 (rank : 139)
Query Neighborhood Hits	453	Target Neighborhood Hits	589	Shared Neighborhood Hits	137
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

LAMC1_MOUSE
NC score	0.290445 (rank : 176)	θ value	5.44631e-05 (rank : 159)
Query Neighborhood Hits	453	Target Neighborhood Hits	856	Shared Neighborhood Hits	232
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA2_HUMAN
NC score	0.290087 (rank : 177)	θ value	0.00175202 (rank : 195)
Query Neighborhood Hits	453	Target Neighborhood Hits	1092	Shared Neighborhood Hits	243
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC2_MOUSE
NC score	0.289258 (rank : 178)	θ value	0.21417 (rank : 296)
Query Neighborhood Hits	453	Target Neighborhood Hits	614	Shared Neighborhood Hits	225
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

NTNG2_MOUSE
NC score	0.289162 (rank : 179)	θ value	0.0563607 (rank : 253)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	190
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

SORL_HUMAN
NC score	0.287393 (rank : 180)	θ value	0.000461057 (rank : 179)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	262
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

NTNG2_HUMAN
NC score	0.286653 (rank : 181)	θ value	0.0113563 (rank : 221)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	186
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LTBP3_HUMAN
NC score	0.286496 (rank : 182)	θ value	0.21417 (rank : 297)
Query Neighborhood Hits	453	Target Neighborhood Hits	502	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NRCAM_MOUSE
NC score	0.286444 (rank : 183)	θ value	3.19293e-05 (rank : 155)
Query Neighborhood Hits	453	Target Neighborhood Hits	432	Shared Neighborhood Hits	132
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

LAMB1_HUMAN
NC score	0.286002 (rank : 184)	θ value	0.0961366 (rank : 266)
Query Neighborhood Hits	453	Target Neighborhood Hits	1018	Shared Neighborhood Hits	240
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

DSCAM_HUMAN
NC score	0.282154 (rank : 185)	θ value	0.00665767 (rank : 210)
Query Neighborhood Hits	453	Target Neighborhood Hits	524	Shared Neighborhood Hits	135
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

KR102_HUMAN
NC score	0.281986 (rank : 186)	θ value	0.813845 (rank : 339)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	156
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

LTBP3_MOUSE
NC score	0.280195 (rank : 187)	θ value	0.813845 (rank : 340)
Query Neighborhood Hits	453	Target Neighborhood Hits	475	Shared Neighborhood Hits	259
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LAMA2_MOUSE
NC score	0.279207 (rank : 188)	θ value	0.00102713 (rank : 187)
Query Neighborhood Hits	453	Target Neighborhood Hits	1198	Shared Neighborhood Hits	241
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KR101_HUMAN
NC score	0.278922 (rank : 189)	θ value	0.813845 (rank : 338)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	150
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

SLIT1_HUMAN
NC score	0.277820 (rank : 190)	θ value	3.77169e-06 (rank : 135)
Query Neighborhood Hits	453	Target Neighborhood Hits	700	Shared Neighborhood Hits	244
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

LAMC1_HUMAN
NC score	0.277262 (rank : 191)	θ value	7.1131e-05 (rank : 161)
Query Neighborhood Hits	453	Target Neighborhood Hits	922	Shared Neighborhood Hits	236
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ATRN_HUMAN
NC score	0.277085 (rank : 192)	θ value	0.00035302 (rank : 175)
Query Neighborhood Hits	453	Target Neighborhood Hits	525	Shared Neighborhood Hits	217
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

SLIT1_MOUSE
NC score	0.276992 (rank : 193)	θ value	6.43352e-06 (rank : 141)
Query Neighborhood Hits	453	Target Neighborhood Hits	715	Shared Neighborhood Hits	247
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ATRN_MOUSE
NC score	0.276632 (rank : 194)	θ value	0.000121331 (rank : 162)
Query Neighborhood Hits	453	Target Neighborhood Hits	519	Shared Neighborhood Hits	211
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

LAMC2_HUMAN
NC score	0.276171 (rank : 195)	θ value	0.0736092 (rank : 259)
Query Neighborhood Hits	453	Target Neighborhood Hits	715	Shared Neighborhood Hits	228
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

L1CAM_HUMAN
NC score	0.273884 (rank : 196)	θ value	4.1701e-05 (rank : 157)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	133
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CREL1_HUMAN
NC score	0.273770 (rank : 197)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	453	Target Neighborhood Hits	441	Shared Neighborhood Hits	197
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

SLIT2_HUMAN
NC score	0.271595 (rank : 198)	θ value	1.87187e-05 (rank : 150)
Query Neighborhood Hits	453	Target Neighborhood Hits	708	Shared Neighborhood Hits	248
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LAMA3_MOUSE
NC score	0.271257 (rank : 199)	θ value	0.0736092 (rank : 258)
Query Neighborhood Hits	453	Target Neighborhood Hits	859	Shared Neighborhood Hits	241
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

L1CAM_MOUSE
NC score	0.269622 (rank : 200)	θ value	0.00020696 (rank : 171)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	135
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CUBN_MOUSE
NC score	0.266647 (rank : 201)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	453	Target Neighborhood Hits	477	Shared Neighborhood Hits	227
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

SLIT2_MOUSE
NC score	0.266192 (rank : 202)	θ value	1.87187e-05 (rank : 151)
Query Neighborhood Hits	453	Target Neighborhood Hits	684	Shared Neighborhood Hits	239
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NTNG1_MOUSE
NC score	0.265993 (rank : 203)	θ value	0.47712 (rank : 318)
Query Neighborhood Hits	453	Target Neighborhood Hits	246	Shared Neighborhood Hits	169
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NFASC_HUMAN
NC score	0.265795 (rank : 204)	θ value	0.0193708 (rank : 231)
Query Neighborhood Hits	453	Target Neighborhood Hits	497	Shared Neighborhood Hits	132
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

PTPRJ_HUMAN
NC score	0.264830 (rank : 205)	θ value	2.88119e-14 (rank : 60)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	92
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

NTNG1_HUMAN
NC score	0.264631 (rank : 206)	θ value	1.06291 (rank : 356)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	171
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ZAN_MOUSE
NC score	0.264547 (rank : 207)	θ value	0.47712 (rank : 320)
Query Neighborhood Hits	453	Target Neighborhood Hits	808	Shared Neighborhood Hits	271
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EDIL3_MOUSE
NC score	0.263117 (rank : 208)	θ value	0.163984 (rank : 279)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	188
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MYOM1_HUMAN
NC score	0.262930 (rank : 209)	θ value	0.62314 (rank : 325)
Query Neighborhood Hits	453	Target Neighborhood Hits	405	Shared Neighborhood Hits	123
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

CUBN_HUMAN
NC score	0.261565 (rank : 210)	θ value	1.06291 (rank : 352)
Query Neighborhood Hits	453	Target Neighborhood Hits	482	Shared Neighborhood Hits	230
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CREL1_MOUSE
NC score	0.261302 (rank : 211)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	453	Target Neighborhood Hits	524	Shared Neighborhood Hits	197
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGFL7_HUMAN
NC score	0.261233 (rank : 212)	θ value	8.99809 (rank : 440)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

MATN2_HUMAN
NC score	0.261164 (rank : 213)	θ value	0.279714 (rank : 311)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	177
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

SLIT3_MOUSE
NC score	0.260030 (rank : 214)	θ value	0.00102713 (rank : 189)
Query Neighborhood Hits	453	Target Neighborhood Hits	700	Shared Neighborhood Hits	243
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

CNTN3_MOUSE
NC score	0.257819 (rank : 215)	θ value	1.17247e-07 (rank : 116)
Query Neighborhood Hits	453	Target Neighborhood Hits	447	Shared Neighborhood Hits	135
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

SLIT3_HUMAN
NC score	0.255746 (rank : 216)	θ value	0.000602161 (rank : 184)
Query Neighborhood Hits	453	Target Neighborhood Hits	682	Shared Neighborhood Hits	234
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

CNTN3_HUMAN
NC score	0.255613 (rank : 217)	θ value	1.09739e-05 (rank : 144)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	138
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

PTPRJ_MOUSE
NC score	0.255547 (rank : 218)	θ value	4.76016e-09 (rank : 100)
Query Neighborhood Hits	453	Target Neighborhood Hits	188	Shared Neighborhood Hits	86
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

CHL1_HUMAN
NC score	0.253744 (rank : 219)	θ value	1.81305 (rank : 367)
Query Neighborhood Hits	453	Target Neighborhood Hits	413	Shared Neighborhood Hits	119
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

CNTN2_HUMAN
NC score	0.252569 (rank : 220)	θ value	7.1131e-05 (rank : 160)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	131
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN5_MOUSE
NC score	0.252150 (rank : 221)	θ value	4.45536e-07 (rank : 126)
Query Neighborhood Hits	453	Target Neighborhood Hits	434	Shared Neighborhood Hits	128
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

TRBM_HUMAN
NC score	0.251867 (rank : 222)	θ value	0.163984 (rank : 284)
Query Neighborhood Hits	453	Target Neighborhood Hits	339	Shared Neighborhood Hits	178
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KRA44_HUMAN
NC score	0.251336 (rank : 223)	θ value	6.88961 (rank : 433)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

EGFL7_MOUSE
NC score	0.251293 (rank : 224)	θ value	3.0926 (rank : 390)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

KRA45_HUMAN
NC score	0.251093 (rank : 225)	θ value	0.163984 (rank : 281)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

MATN2_MOUSE
NC score	0.250991 (rank : 226)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	453	Target Neighborhood Hits	356	Shared Neighborhood Hits	170
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

CNTN2_MOUSE
NC score	0.250014 (rank : 227)	θ value	2.44474e-05 (rank : 152)
Query Neighborhood Hits	453	Target Neighborhood Hits	450	Shared Neighborhood Hits	130
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

GAS6_MOUSE
NC score	0.249629 (rank : 228)	θ value	0.21417 (rank : 291)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	196
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CNTN5_HUMAN
NC score	0.248375 (rank : 229)	θ value	1.17247e-07 (rank : 117)
Query Neighborhood Hits	453	Target Neighborhood Hits	446	Shared Neighborhood Hits	132
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

GAS6_HUMAN
NC score	0.248373 (rank : 230)	θ value	1.38821 (rank : 364)
Query Neighborhood Hits	453	Target Neighborhood Hits	348	Shared Neighborhood Hits	201
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NFASC_MOUSE
NC score	0.247934 (rank : 231)	θ value	0.00020696 (rank : 172)
Query Neighborhood Hits	453	Target Neighborhood Hits	475	Shared Neighborhood Hits	129
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

FBLN2_HUMAN
NC score	0.246636 (rank : 232)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	188
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

PUNC_HUMAN
NC score	0.244590 (rank : 233)	θ value	0.62314 (rank : 327)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	123
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

LRP2_HUMAN
NC score	0.243917 (rank : 234)	θ value	0.0193708 (rank : 230)
Query Neighborhood Hits	453	Target Neighborhood Hits	573	Shared Neighborhood Hits	271
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

SCUB3_HUMAN
NC score	0.243864 (rank : 235)	θ value	6.88961 (rank : 436)
Query Neighborhood Hits	453	Target Neighborhood Hits	428	Shared Neighborhood Hits	217
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

KR10C_HUMAN
NC score	0.243383 (rank : 236)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	135
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

PUNC_MOUSE
NC score	0.242185 (rank : 237)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	453	Target Neighborhood Hits	501	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

FBLN2_MOUSE
NC score	0.242017 (rank : 238)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	453	Target Neighborhood Hits	505	Shared Neighborhood Hits	204
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

KRA11_HUMAN
NC score	0.241945 (rank : 239)	θ value	4.03905 (rank : 409)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	99
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

MYOM1_MOUSE
NC score	0.241807 (rank : 240)	θ value	1.81305 (rank : 372)
Query Neighborhood Hits	453	Target Neighborhood Hits	415	Shared Neighborhood Hits	129
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

CNTN1_HUMAN
NC score	0.241739 (rank : 241)	θ value	0.000786445 (rank : 185)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	121
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

KRA47_HUMAN
NC score	0.241710 (rank : 242)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	453	Target Neighborhood Hits	204	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

SCUB3_MOUSE
NC score	0.241697 (rank : 243)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	453	Target Neighborhood Hits	442	Shared Neighborhood Hits	221
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

EDIL3_HUMAN
NC score	0.240597 (rank : 244)	θ value	0.21417 (rank : 290)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	172
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CNTN1_MOUSE
NC score	0.240351 (rank : 245)	θ value	0.000270298 (rank : 173)
Query Neighborhood Hits	453	Target Neighborhood Hits	422	Shared Neighborhood Hits	122
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

TRBM_MOUSE
NC score	0.239814 (rank : 246)	θ value	0.163984 (rank : 285)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	187
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KR105_HUMAN
NC score	0.239471 (rank : 247)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	156
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

UROM_HUMAN
NC score	0.239436 (rank : 248)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	453	Target Neighborhood Hits	284	Shared Neighborhood Hits	173
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

RELN_MOUSE
NC score	0.239029 (rank : 249)	θ value	0.000121331 (rank : 166)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	159
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

KR10B_HUMAN
NC score	0.238932 (rank : 250)	θ value	0.0148317 (rank : 223)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	150
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

I12R2_HUMAN
NC score	0.237584 (rank : 251)	θ value	0.0431538 (rank : 245)
Query Neighborhood Hits	453	Target Neighborhood Hits	163	Shared Neighborhood Hits	98
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

EGF_MOUSE
NC score	0.237237 (rank : 252)	θ value	3.0926 (rank : 391)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	196
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

MYOM2_HUMAN
NC score	0.236551 (rank : 253)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	120
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

KRA13_HUMAN
NC score	0.235891 (rank : 254)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	453	Target Neighborhood Hits	144	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

ROBO2_MOUSE
NC score	0.235531 (rank : 255)	θ value	4.45536e-07 (rank : 127)
Query Neighborhood Hits	453	Target Neighborhood Hits	504	Shared Neighborhood Hits	131
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

RELN_HUMAN
NC score	0.234446 (rank : 256)	θ value	0.000158464 (rank : 169)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	158
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

C1QR1_HUMAN
NC score	0.234406 (rank : 257)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	453	Target Neighborhood Hits	493	Shared Neighborhood Hits	206
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

KR108_HUMAN
NC score	0.234074 (rank : 258)	θ value	2.36792 (rank : 379)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	132
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

ROBO3_HUMAN
NC score	0.233542 (rank : 259)	θ value	2.44474e-05 (rank : 153)
Query Neighborhood Hits	453	Target Neighborhood Hits	570	Shared Neighborhood Hits	137
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

CHL1_MOUSE
NC score	0.233490 (rank : 260)	θ value	0.279714 (rank : 307)
Query Neighborhood Hits	453	Target Neighborhood Hits	402	Shared Neighborhood Hits	117
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

ROBO2_HUMAN
NC score	0.233384 (rank : 261)	θ value	6.43352e-06 (rank : 140)
Query Neighborhood Hits	453	Target Neighborhood Hits	479	Shared Neighborhood Hits	130
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

KRA92_HUMAN
NC score	0.232471 (rank : 262)	θ value	0.125558 (rank : 272)
Query Neighborhood Hits	453	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

PROS_MOUSE
NC score	0.232024 (rank : 263)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	194
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_HUMAN
NC score	0.231858 (rank : 264)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	453	Target Neighborhood Hits	340	Shared Neighborhood Hits	199
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

NID2_HUMAN
NC score	0.231524 (rank : 265)	θ value	5.27518 (rank : 424)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	190
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

UROM_MOUSE
NC score	0.231518 (rank : 266)	θ value	0.21417 (rank : 301)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	176
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

KR109_HUMAN
NC score	0.229952 (rank : 267)	θ value	2.36792 (rank : 380)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	138
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

CNTN4_MOUSE
NC score	0.228608 (rank : 268)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	453	Target Neighborhood Hits	445	Shared Neighborhood Hits	122
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

KRA93_HUMAN
NC score	0.228510 (rank : 269)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	453	Target Neighborhood Hits	203	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

HMCN1_HUMAN
NC score	0.227623 (rank : 270)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	453	Target Neighborhood Hits	983	Shared Neighborhood Hits	270
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CNTN6_HUMAN
NC score	0.227384 (rank : 271)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	453	Target Neighborhood Hits	422	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CNTN4_HUMAN
NC score	0.226574 (rank : 272)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

ROBO1_MOUSE
NC score	0.226465 (rank : 273)	θ value	0.00298849 (rank : 199)
Query Neighborhood Hits	453	Target Neighborhood Hits	559	Shared Neighborhood Hits	129
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

LDLR_HUMAN
NC score	0.225984 (rank : 274)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	453	Target Neighborhood Hits	375	Shared Neighborhood Hits	208
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LAMA4_MOUSE
NC score	0.224524 (rank : 275)	θ value	0.0563607 (rank : 250)
Query Neighborhood Hits	453	Target Neighborhood Hits	584	Shared Neighborhood Hits	162
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA3_HUMAN
NC score	0.223317 (rank : 276)	θ value	4.03905 (rank : 411)
Query Neighborhood Hits	453	Target Neighborhood Hits	760	Shared Neighborhood Hits	196
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

FBLN1_MOUSE
NC score	0.221646 (rank : 277)	θ value	2.36792 (rank : 377)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	186
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN1_HUMAN
NC score	0.221402 (rank : 278)	θ value	4.03905 (rank : 408)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	184
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

KRA94_HUMAN
NC score	0.221207 (rank : 279)	θ value	4.03905 (rank : 410)
Query Neighborhood Hits	453	Target Neighborhood Hits	204	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

PTPRM_MOUSE
NC score	0.221202 (rank : 280)	θ value	0.0563607 (rank : 256)
Query Neighborhood Hits	453	Target Neighborhood Hits	238	Shared Neighborhood Hits	117
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

EGFL8_HUMAN
NC score	0.221025 (rank : 281)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	160
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

NID1_MOUSE
NC score	0.220768 (rank : 282)	θ value	5.27518 (rank : 423)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	183
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

CNTN6_MOUSE
NC score	0.220767 (rank : 283)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	453	Target Neighborhood Hits	429	Shared Neighborhood Hits	121
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

C1QR1_MOUSE
NC score	0.220545 (rank : 284)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	453	Target Neighborhood Hits	342	Shared Neighborhood Hits	183
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

ROBO3_MOUSE
NC score	0.220479 (rank : 285)	θ value	0.00134147 (rank : 194)
Query Neighborhood Hits	453	Target Neighborhood Hits	524	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

LRP8_MOUSE
NC score	0.219921 (rank : 286)	θ value	0.125558 (rank : 273)
Query Neighborhood Hits	453	Target Neighborhood Hits	385	Shared Neighborhood Hits	188
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

PTPRM_HUMAN
NC score	0.219667 (rank : 287)	θ value	0.0563607 (rank : 255)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	117
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

EGFL8_MOUSE
NC score	0.219620 (rank : 288)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	453	Target Neighborhood Hits	266	Shared Neighborhood Hits	162
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

VLDLR_HUMAN
NC score	0.219574 (rank : 289)	θ value	4.03905 (rank : 417)
Query Neighborhood Hits	453	Target Neighborhood Hits	383	Shared Neighborhood Hits	200
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
NC score	0.219505 (rank : 290)	θ value	5.27518 (rank : 428)
Query Neighborhood Hits	453	Target Neighborhood Hits	360	Shared Neighborhood Hits	192
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

KR412_HUMAN
NC score	0.218871 (rank : 291)	θ value	3.0926 (rank : 396)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

ROBO1_HUMAN
NC score	0.218372 (rank : 292)	θ value	0.000602161 (rank : 183)
Query Neighborhood Hits	453	Target Neighborhood Hits	529	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

NID2_MOUSE
NC score	0.218080 (rank : 293)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	453	Target Neighborhood Hits	338	Shared Neighborhood Hits	177
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID1_HUMAN
NC score	0.218010 (rank : 294)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	185
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SUSD1_HUMAN
NC score	0.217088 (rank : 295)	θ value	3.0926 (rank : 403)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	154
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

MATN3_HUMAN
NC score	0.216200 (rank : 296)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	135
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

BOC_HUMAN
NC score	0.215637 (rank : 297)	θ value	0.00298849 (rank : 198)
Query Neighborhood Hits	453	Target Neighborhood Hits	543	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

MYPC2_MOUSE
NC score	0.214899 (rank : 298)	θ value	0.00390308 (rank : 203)
Query Neighborhood Hits	453	Target Neighborhood Hits	297	Shared Neighborhood Hits	100
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

LAMA4_HUMAN
NC score	0.214054 (rank : 299)	θ value	0.0252991 (rank : 235)
Query Neighborhood Hits	453	Target Neighborhood Hits	708	Shared Neighborhood Hits	166
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MATN3_MOUSE
NC score	0.213724 (rank : 300)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	137
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LRP4_MOUSE
NC score	0.213391 (rank : 301)	θ value	0.000602161 (rank : 182)
Query Neighborhood Hits	453	Target Neighborhood Hits	351	Shared Neighborhood Hits	188
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

KRA99_HUMAN
NC score	0.213075 (rank : 302)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	453	Target Neighborhood Hits	173	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

PCSK5_MOUSE
NC score	0.212694 (rank : 303)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	453	Target Neighborhood Hits	613	Shared Neighborhood Hits	235
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CSF3R_HUMAN
NC score	0.212330 (rank : 304)	θ value	0.000461057 (rank : 178)
Query Neighborhood Hits	453	Target Neighborhood Hits	140	Shared Neighborhood Hits	87
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

LDLR_MOUSE
NC score	0.211912 (rank : 305)	θ value	0.163984 (rank : 282)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	206
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP4_HUMAN
NC score	0.211713 (rank : 306)	θ value	0.000602161 (rank : 181)
Query Neighborhood Hits	453	Target Neighborhood Hits	355	Shared Neighborhood Hits	186
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

KRA98_HUMAN
NC score	0.210281 (rank : 307)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	453	Target Neighborhood Hits	185	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

EGF_HUMAN
NC score	0.210215 (rank : 308)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	185
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

FBLN4_HUMAN
NC score	0.209781 (rank : 309)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	165
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

KR414_HUMAN
NC score	0.209372 (rank : 310)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

TIE1_MOUSE
NC score	0.208815 (rank : 311)	θ value	3.52202e-12 (rank : 68)
Query Neighborhood Hits	453	Target Neighborhood Hits	1266	Shared Neighborhood Hits	313
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

I12R2_MOUSE
NC score	0.208772 (rank : 312)	θ value	0.365318 (rank : 315)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	92
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

MATN4_HUMAN
NC score	0.208606 (rank : 313)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	153
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

TIE1_HUMAN
NC score	0.208483 (rank : 314)	θ value	1.02475e-11 (rank : 75)
Query Neighborhood Hits	453	Target Neighborhood Hits	1241	Shared Neighborhood Hits	315
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

PTPRT_MOUSE
NC score	0.208005 (rank : 315)	θ value	0.00869519 (rank : 214)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	108
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.207931 (rank : 316)	θ value	0.00869519 (rank : 213)
Query Neighborhood Hits	453	Target Neighborhood Hits	217	Shared Neighborhood Hits	107
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

CRIM1_HUMAN
NC score	0.206358 (rank : 317)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	453	Target Neighborhood Hits	362	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

FBLN5_HUMAN
NC score	0.206273 (rank : 318)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	184
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

IL6RB_MOUSE
NC score	0.205812 (rank : 319)	θ value	3.0926 (rank : 395)
Query Neighborhood Hits	453	Target Neighborhood Hits	168	Shared Neighborhood Hits	100
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

BOC_MOUSE
NC score	0.205702 (rank : 320)	θ value	0.0193708 (rank : 227)
Query Neighborhood Hits	453	Target Neighborhood Hits	433	Shared Neighborhood Hits	110
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

NET2_MOUSE
NC score	0.205155 (rank : 321)	θ value	0.00509761 (rank : 206)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	146
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

PTPRU_HUMAN
NC score	0.204600 (rank : 322)	θ value	0.00869519 (rank : 215)
Query Neighborhood Hits	453	Target Neighborhood Hits	237	Shared Neighborhood Hits	116
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

CDON_MOUSE
NC score	0.204557 (rank : 323)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	453	Target Neighborhood Hits	410	Shared Neighborhood Hits	112
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

TSP4_MOUSE
NC score	0.204359 (rank : 324)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

FBLN4_MOUSE
NC score	0.203293 (rank : 325)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	157
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

CDON_HUMAN
NC score	0.203173 (rank : 326)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	453	Target Neighborhood Hits	412	Shared Neighborhood Hits	111
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

TSP4_HUMAN
NC score	0.202335 (rank : 327)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	172
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TIE2_HUMAN
NC score	0.201824 (rank : 328)	θ value	5.25075e-16 (rank : 57)
Query Neighborhood Hits	453	Target Neighborhood Hits	1192	Shared Neighborhood Hits	294
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

IL6RB_HUMAN
NC score	0.201745 (rank : 329)	θ value	1.06291 (rank : 354)
Query Neighborhood Hits	453	Target Neighborhood Hits	181	Shared Neighborhood Hits	103
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

MYPC3_HUMAN
NC score	0.201073 (rank : 330)	θ value	1.81305 (rank : 373)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	107
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MATN4_MOUSE
NC score	0.200872 (rank : 331)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	149
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

NET2_HUMAN
NC score	0.200839 (rank : 332)	θ value	0.0113563 (rank : 220)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	140
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

FBLN5_MOUSE
NC score	0.200632 (rank : 333)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	178
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LRP8_HUMAN
NC score	0.200240 (rank : 334)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	453	Target Neighborhood Hits	346	Shared Neighborhood Hits	174
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

FRAS1_HUMAN
NC score	0.199665 (rank : 335)	θ value	1.38821 (rank : 363)
Query Neighborhood Hits	453	Target Neighborhood Hits	759	Shared Neighborhood Hits	235
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SSPO_MOUSE
NC score	0.199492 (rank : 336)	θ value	3.0926 (rank : 402)
Query Neighborhood Hits	453	Target Neighborhood Hits	800	Shared Neighborhood Hits	267
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

NPHN_HUMAN
NC score	0.199435 (rank : 337)	θ value	0.21417 (rank : 300)
Query Neighborhood Hits	453	Target Neighborhood Hits	362	Shared Neighborhood Hits	96
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

COMP_MOUSE
NC score	0.199362 (rank : 338)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	182
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

FBLN3_HUMAN
NC score	0.199091 (rank : 339)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	167
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

MYPC2_HUMAN
NC score	0.199059 (rank : 340)	θ value	0.21417 (rank : 298)
Query Neighborhood Hits	453	Target Neighborhood Hits	316	Shared Neighborhood Hits	106
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

TIE2_MOUSE
NC score	0.197494 (rank : 341)	θ value	2.0648e-12 (rank : 67)
Query Neighborhood Hits	453	Target Neighborhood Hits	1204	Shared Neighborhood Hits	298
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

CSPG3_MOUSE
NC score	0.197203 (rank : 342)	θ value	3.0926 (rank : 389)
Query Neighborhood Hits	453	Target Neighborhood Hits	657	Shared Neighborhood Hits	190
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CFC1_HUMAN
NC score	0.194917 (rank : 343)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	453	Target Neighborhood Hits	148	Shared Neighborhood Hits	124
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CSPG2_MOUSE
NC score	0.194246 (rank : 344)	θ value	0.0431538 (rank : 243)
Query Neighborhood Hits	453	Target Neighborhood Hits	711	Shared Neighborhood Hits	191
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
NC score	0.193913 (rank : 345)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	453	Target Neighborhood Hits	676	Shared Neighborhood Hits	188
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MYPC3_MOUSE
NC score	0.193644 (rank : 346)	θ value	0.813845 (rank : 341)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	106
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MFGM_MOUSE
NC score	0.192954 (rank : 347)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	142
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

FBLN3_MOUSE
NC score	0.192891 (rank : 348)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	453	Target Neighborhood Hits	279	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

CSPG2_HUMAN
NC score	0.192837 (rank : 349)	θ value	0.125558 (rank : 269)
Query Neighborhood Hits	453	Target Neighborhood Hits	681	Shared Neighborhood Hits	194
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

GRN_HUMAN
NC score	0.192323 (rank : 350)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	149
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

NET4_HUMAN
NC score	0.191491 (rank : 351)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	134
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

EMR1_HUMAN
NC score	0.190784 (rank : 352)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	173
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

NCAM2_MOUSE
NC score	0.190675 (rank : 353)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	453	Target Neighborhood Hits	472	Shared Neighborhood Hits	118
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NET4_MOUSE
NC score	0.190671 (rank : 354)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	135
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

VWF_HUMAN
NC score	0.190667 (rank : 355)	θ value	0.163984 (rank : 286)
Query Neighborhood Hits	453	Target Neighborhood Hits	396	Shared Neighborhood Hits	175
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FRAS1_MOUSE
NC score	0.186314 (rank : 356)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	453	Target Neighborhood Hits	747	Shared Neighborhood Hits	225
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

COMP_HUMAN
NC score	0.183968 (rank : 357)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	453	Target Neighborhood Hits	258	Shared Neighborhood Hits	170
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NPHN_MOUSE
NC score	0.183885 (rank : 358)	θ value	3.0926 (rank : 400)
Query Neighborhood Hits	453	Target Neighborhood Hits	370	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

GRN_MOUSE
NC score	0.183658 (rank : 359)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	453	Target Neighborhood Hits	248	Shared Neighborhood Hits	152
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KR103_HUMAN
NC score	0.182171 (rank : 360)	θ value	6.88961 (rank : 432)
Query Neighborhood Hits	453	Target Neighborhood Hits	212	Shared Neighborhood Hits	124
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KRA42_HUMAN
NC score	0.182171 (rank : 361)	θ value	1.81305 (rank : 371)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

MYPC1_HUMAN
NC score	0.181959 (rank : 362)	θ value	0.0736092 (rank : 260)
Query Neighborhood Hits	453	Target Neighborhood Hits	303	Shared Neighborhood Hits	97
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

TITIN_HUMAN
NC score	0.181253 (rank : 363)	θ value	1.5773e-20 (rank : 53)
Query Neighborhood Hits	453	Target Neighborhood Hits	2923	Shared Neighborhood Hits	178
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CFC1_MOUSE
NC score	0.180368 (rank : 364)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	108
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

KR10A_HUMAN
NC score	0.180052 (rank : 365)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	453	Target Neighborhood Hits	232	Shared Neighborhood Hits	131
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

CELR3_HUMAN
NC score	0.178091 (rank : 366)	θ value	0.00020696 (rank : 170)
Query Neighborhood Hits	453	Target Neighborhood Hits	680	Shared Neighborhood Hits	236
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

NCAM2_HUMAN
NC score	0.178023 (rank : 367)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	453	Target Neighborhood Hits	441	Shared Neighborhood Hits	115
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

CELR1_HUMAN
NC score	0.177582 (rank : 368)	θ value	4.1701e-05 (rank : 156)
Query Neighborhood Hits	453	Target Neighborhood Hits	613	Shared Neighborhood Hits	206
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR3_MOUSE
NC score	0.177336 (rank : 369)	θ value	0.000121331 (rank : 163)
Query Neighborhood Hits	453	Target Neighborhood Hits	687	Shared Neighborhood Hits	235
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

EMR2_HUMAN
NC score	0.176210 (rank : 370)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	453	Target Neighborhood Hits	345	Shared Neighborhood Hits	171
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FATH_HUMAN
NC score	0.175891 (rank : 371)	θ value	0.0252991 (rank : 232)
Query Neighborhood Hits	453	Target Neighborhood Hits	570	Shared Neighborhood Hits	216
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

CELR1_MOUSE
NC score	0.175195 (rank : 372)	θ value	4.92598e-06 (rank : 136)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	218
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CD97_HUMAN
NC score	0.174993 (rank : 373)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	453	Target Neighborhood Hits	353	Shared Neighborhood Hits	172
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CELR2_HUMAN
NC score	0.174729 (rank : 374)	θ value	0.0113563 (rank : 216)
Query Neighborhood Hits	453	Target Neighborhood Hits	657	Shared Neighborhood Hits	234
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

PTPRO_HUMAN
NC score	0.174286 (rank : 375)	θ value	2.36792 (rank : 385)
Query Neighborhood Hits	453	Target Neighborhood Hits	139	Shared Neighborhood Hits	58
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PROZ_MOUSE
NC score	0.172930 (rank : 376)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	453	Target Neighborhood Hits	410	Shared Neighborhood Hits	169
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PTPRK_MOUSE
NC score	0.170600 (rank : 377)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	453	Target Neighborhood Hits	223	Shared Neighborhood Hits	102
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

NCA11_MOUSE
NC score	0.170593 (rank : 378)	θ value	0.125558 (rank : 276)
Query Neighborhood Hits	453	Target Neighborhood Hits	661	Shared Neighborhood Hits	111
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NET1_HUMAN
NC score	0.169919 (rank : 379)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	109
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

PROZ_HUMAN
NC score	0.169761 (rank : 380)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	453	Target Neighborhood Hits	422	Shared Neighborhood Hits	173
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PTPRK_HUMAN
NC score	0.169510 (rank : 381)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	453	Target Neighborhood Hits	228	Shared Neighborhood Hits	104
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

LIFR_MOUSE
NC score	0.168073 (rank : 382)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	453	Target Neighborhood Hits	127	Shared Neighborhood Hits	79
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

LIFR_HUMAN
NC score	0.167844 (rank : 383)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	453	Target Neighborhood Hits	130	Shared Neighborhood Hits	81
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

NET1_MOUSE
NC score	0.167604 (rank : 384)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	453	Target Neighborhood Hits	151	Shared Neighborhood Hits	107
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NCA11_HUMAN
NC score	0.167247 (rank : 385)	θ value	0.813845 (rank : 342)
Query Neighborhood Hits	453	Target Neighborhood Hits	443	Shared Neighborhood Hits	107
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

KRA15_HUMAN
NC score	0.166745 (rank : 386)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

EMR1_MOUSE
NC score	0.165237 (rank : 387)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	453	Target Neighborhood Hits	349	Shared Neighborhood Hits	159
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

HABP2_HUMAN
NC score	0.164945 (rank : 388)	θ value	0.000121331 (rank : 165)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	187
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

VWF_MOUSE
NC score	0.163998 (rank : 389)	θ value	8.99809 (rank : 453)
Query Neighborhood Hits	453	Target Neighborhood Hits	381	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

HABP2_MOUSE
NC score	0.163969 (rank : 390)	θ value	1.43324e-05 (rank : 147)
Query Neighborhood Hits	453	Target Neighborhood Hits	445	Shared Neighborhood Hits	189
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

TSP3_MOUSE
NC score	0.163887 (rank : 391)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	152
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

NFX1_HUMAN
NC score	0.163838 (rank : 392)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	453	Target Neighborhood Hits	405	Shared Neighborhood Hits	141
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

LYAM2_MOUSE
NC score	0.161590 (rank : 393)	θ value	0.0563607 (rank : 252)
Query Neighborhood Hits	453	Target Neighborhood Hits	420	Shared Neighborhood Hits	186
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CD248_HUMAN
NC score	0.161415 (rank : 394)	θ value	0.813845 (rank : 332)
Query Neighborhood Hits	453	Target Neighborhood Hits	679	Shared Neighborhood Hits	174
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ELTD1_MOUSE
NC score	0.160580 (rank : 395)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	136
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ROBO4_HUMAN
NC score	0.159568 (rank : 396)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	453	Target Neighborhood Hits	364	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

NCA12_MOUSE
NC score	0.159239 (rank : 397)	θ value	0.21417 (rank : 299)
Query Neighborhood Hits	453	Target Neighborhood Hits	399	Shared Neighborhood Hits	96
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

LYAM1_MOUSE
NC score	0.158898 (rank : 398)	θ value	0.0431538 (rank : 247)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	142
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TSP3_HUMAN
NC score	0.158304 (rank : 399)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	453	Target Neighborhood Hits	250	Shared Neighborhood Hits	146
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

CD248_MOUSE
NC score	0.158225 (rank : 400)	θ value	4.03905 (rank : 406)
Query Neighborhood Hits	453	Target Neighborhood Hits	578	Shared Neighborhood Hits	153
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

LCE1C_HUMAN
NC score	0.157898 (rank : 401)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	453	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

ROBO4_MOUSE
NC score	0.157635 (rank : 402)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

KALM_HUMAN
NC score	0.157103 (rank : 403)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	453	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

CSF3R_MOUSE
NC score	0.156089 (rank : 404)	θ value	0.163984 (rank : 278)
Query Neighborhood Hits	453	Target Neighborhood Hits	104	Shared Neighborhood Hits	68
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CELR2_MOUSE
NC score	0.156088 (rank : 405)	θ value	1.38821 (rank : 358)
Query Neighborhood Hits	453	Target Neighborhood Hits	584	Shared Neighborhood Hits	211
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

TDGF1_MOUSE
NC score	0.155860 (rank : 406)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	453	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

LCE1B_HUMAN
NC score	0.155011 (rank : 407)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	453	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

TSP1_MOUSE
NC score	0.152230 (rank : 408)	θ value	0.62314 (rank : 328)
Query Neighborhood Hits	453	Target Neighborhood Hits	396	Shared Neighborhood Hits	179
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

LYAM2_HUMAN
NC score	0.152052 (rank : 409)	θ value	0.0113563 (rank : 219)
Query Neighborhood Hits	453	Target Neighborhood Hits	394	Shared Neighborhood Hits	165
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TSP1_HUMAN
NC score	0.151436 (rank : 410)	θ value	1.38821 (rank : 366)
Query Neighborhood Hits	453	Target Neighborhood Hits	389	Shared Neighborhood Hits	180
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TEFF2_HUMAN
NC score	0.150471 (rank : 411)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
NC score	0.150047 (rank : 412)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	453	Target Neighborhood Hits	214	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

NRG2_MOUSE
NC score	0.148033 (rank : 413)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	157
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

MUC5B_HUMAN
NC score	0.147930 (rank : 414)	θ value	3.0926 (rank : 399)
Query Neighborhood Hits	453	Target Neighborhood Hits	1020	Shared Neighborhood Hits	218
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NCA12_HUMAN
NC score	0.147590 (rank : 415)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	453	Target Neighborhood Hits	437	Shared Neighborhood Hits	102
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

ADA11_HUMAN
NC score	0.147317 (rank : 416)	θ value	0.0330416 (rank : 236)
Query Neighborhood Hits	453	Target Neighborhood Hits	259	Shared Neighborhood Hits	151
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
NC score	0.146764 (rank : 417)	θ value	0.0330416 (rank : 237)
Query Neighborhood Hits	453	Target Neighborhood Hits	263	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADAM8_HUMAN
NC score	0.145950 (rank : 418)	θ value	8.40245e-06 (rank : 142)
Query Neighborhood Hits	453	Target Neighborhood Hits	327	Shared Neighborhood Hits	176
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CD97_MOUSE
NC score	0.145698 (rank : 419)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	453	Target Neighborhood Hits	295	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

MYBPH_MOUSE
NC score	0.145487 (rank : 420)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	96
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

OBSL1_HUMAN
NC score	0.144457 (rank : 421)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	453	Target Neighborhood Hits	354	Shared Neighborhood Hits	68
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

ADAM8_MOUSE
NC score	0.143139 (rank : 422)	θ value	0.00665767 (rank : 209)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	169
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ZAN_HUMAN
NC score	0.142748 (rank : 423)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	453	Target Neighborhood Hits	679	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ADA15_MOUSE
NC score	0.140652 (rank : 424)	θ value	0.00228821 (rank : 196)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	177
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

MT3_MOUSE
NC score	0.140250 (rank : 425)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	453	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

ITL1B_MOUSE
NC score	0.139924 (rank : 426)	θ value	0.0252991 (rank : 233)
Query Neighborhood Hits	453	Target Neighborhood Hits	36	Shared Neighborhood Hits	35
SwissProt Accessions	Q80ZA0	Gene names	Itln1b, Itln2, Itlnb
Domain Architecture	No domain graphic available
Description	Intelectin-1b precursor (Intelectin-2).

KR410_HUMAN
NC score	0.138967 (rank : 427)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

LCE1E_HUMAN
NC score	0.137460 (rank : 428)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

CT075_HUMAN
NC score	0.136917 (rank : 429)	θ value	0.0148317 (rank : 222)
Query Neighborhood Hits	453	Target Neighborhood Hits	387	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

ADA15_HUMAN
NC score	0.136728 (rank : 430)	θ value	0.00134147 (rank : 190)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	174
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

LYAM3_MOUSE
NC score	0.136273 (rank : 431)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	453	Target Neighborhood Hits	390	Shared Neighborhood Hits	154
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

NRG2_HUMAN
NC score	0.136139 (rank : 432)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	141
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

LYAM1_HUMAN
NC score	0.135334 (rank : 433)	θ value	3.0926 (rank : 398)
Query Neighborhood Hits	453	Target Neighborhood Hits	315	Shared Neighborhood Hits	141
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MYBPH_HUMAN
NC score	0.134940 (rank : 434)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	453	Target Neighborhood Hits	256	Shared Neighborhood Hits	87
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

LCE1D_HUMAN
NC score	0.134714 (rank : 435)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1F_HUMAN
NC score	0.134632 (rank : 436)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	453	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

CD45_HUMAN
NC score	0.134621 (rank : 437)	θ value	0.0330416 (rank : 239)
Query Neighborhood Hits	453	Target Neighborhood Hits	243	Shared Neighborhood Hits	55
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

MATN1_HUMAN
NC score	0.133736 (rank : 438)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	78
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
NC score	0.133466 (rank : 439)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	453	Target Neighborhood Hits	186	Shared Neighborhood Hits	75
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

ITL1A_MOUSE
NC score	0.133206 (rank : 440)	θ value	0.0431538 (rank : 246)
Query Neighborhood Hits	453	Target Neighborhood Hits	33	Shared Neighborhood Hits	32
SwissProt Accessions	O88310	Gene names	Itln1a, Intl, Itln, Itlna
Domain Architecture	No domain graphic available
Description	Intelectin-1a precursor (Intestinal lactoferrin receptor) (Galactofuranose-binding lectin).

FGRL1_HUMAN
NC score	0.132275 (rank : 441)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
NC score	0.131146 (rank : 442)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	69
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

ADA23_HUMAN
NC score	0.130908 (rank : 443)	θ value	1.06291 (rank : 350)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	146
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

MYPN_HUMAN
NC score	0.130354 (rank : 444)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	453	Target Neighborhood Hits	418	Shared Neighborhood Hits	72
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

LCE1A_HUMAN
NC score	0.129990 (rank : 445)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

MYOTI_MOUSE
NC score	0.129461 (rank : 446)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	453	Target Neighborhood Hits	297	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MT4_MOUSE
NC score	0.128689 (rank : 447)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MYPN_MOUSE
NC score	0.128394 (rank : 448)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	453	Target Neighborhood Hits	421	Shared Neighborhood Hits	70
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

MYOTI_HUMAN
NC score	0.128318 (rank : 449)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

ADA23_MOUSE
NC score	0.128121 (rank : 450)	θ value	1.06291 (rank : 351)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	153
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

I12R1_HUMAN
NC score	0.127175 (rank : 451)	θ value	0.125558 (rank : 271)
Query Neighborhood Hits	453	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

ADA22_MOUSE
NC score	0.126756 (rank : 452)	θ value	0.0330416 (rank : 238)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

TDGF1_HUMAN
NC score	0.126131 (rank : 453)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	453	Target Neighborhood Hits	132	Shared Neighborhood Hits	100
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

ADA18_MOUSE
NC score	0.125935 (rank : 454)	θ value	0.279714 (rank : 302)
Query Neighborhood Hits	453	Target Neighborhood Hits	227	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

MAMC1_MOUSE
NC score	0.125873 (rank : 455)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	453	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

RIMB2_MOUSE
NC score	0.125393 (rank : 456)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	453	Target Neighborhood Hits	246	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

MAMC1_HUMAN
NC score	0.125167 (rank : 457)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	453	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

RIMB2_HUMAN
NC score	0.125086 (rank : 458)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	453	Target Neighborhood Hits	263	Shared Neighborhood Hits	52
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

MDGA1_HUMAN
NC score	0.124061 (rank : 459)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

I12R1_MOUSE
NC score	0.123985 (rank : 460)	θ value	3.0926 (rank : 394)
Query Neighborhood Hits	453	Target Neighborhood Hits	70	Shared Neighborhood Hits	49
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

TDGF2_HUMAN
NC score	0.123444 (rank : 461)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	453	Target Neighborhood Hits	131	Shared Neighborhood Hits	99
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

ADA28_HUMAN
NC score	0.123193 (rank : 462)	θ value	0.00869519 (rank : 211)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

TSP2_MOUSE
NC score	0.123076 (rank : 463)	θ value	5.27518 (rank : 427)
Query Neighborhood Hits	453	Target Neighborhood Hits	352	Shared Neighborhood Hits	169
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_HUMAN
NC score	0.122024 (rank : 464)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	453	Target Neighborhood Hits	359	Shared Neighborhood Hits	169
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

NRG1_HUMAN
NC score	0.121955 (rank : 465)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	124
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

HGFA_MOUSE
NC score	0.121513 (rank : 466)	θ value	0.0563607 (rank : 249)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	156
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ESM1_HUMAN
NC score	0.121423 (rank : 467)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

VEGFC_HUMAN
NC score	0.121161 (rank : 468)	θ value	0.813845 (rank : 349)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

HCFC2_MOUSE
NC score	0.120645 (rank : 469)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	453	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

LCE3A_HUMAN
NC score	0.119821 (rank : 470)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	453	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

CT075_MOUSE
NC score	0.119364 (rank : 471)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	69
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

HGFA_HUMAN
NC score	0.119213 (rank : 472)	θ value	1.81305 (rank : 370)
Query Neighborhood Hits	453	Target Neighborhood Hits	436	Shared Neighborhood Hits	159
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LYAM3_HUMAN
NC score	0.119170 (rank : 473)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	453	Target Neighborhood Hits	378	Shared Neighborhood Hits	156
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

KAZD1_HUMAN
NC score	0.119077 (rank : 474)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	453	Target Neighborhood Hits	248	Shared Neighborhood Hits	75
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

ADAM9_MOUSE
NC score	0.118881 (rank : 475)	θ value	0.813845 (rank : 330)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	151
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

IL27B_HUMAN
NC score	0.118839 (rank : 476)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	453	Target Neighborhood Hits	80	Shared Neighborhood Hits	56
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

CD45_MOUSE
NC score	0.118764 (rank : 477)	θ value	0.279714 (rank : 306)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	51
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

LRP6_HUMAN
NC score	0.118724 (rank : 478)	θ value	2.36792 (rank : 382)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	101
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MT3_HUMAN
NC score	0.118574 (rank : 479)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	453	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

KR413_HUMAN
NC score	0.118023 (rank : 480)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

ADA32_MOUSE
NC score	0.117823 (rank : 481)	θ value	0.00665767 (rank : 208)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	140
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

MALT1_HUMAN
NC score	0.117750 (rank : 482)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

PROC_MOUSE
NC score	0.117266 (rank : 483)	θ value	1.06291 (rank : 357)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	174
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

KAZD1_MOUSE
NC score	0.116528 (rank : 484)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	453	Target Neighborhood Hits	281	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

ADA22_HUMAN
NC score	0.116147 (rank : 485)	θ value	0.21417 (rank : 288)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	117
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADAM2_MOUSE
NC score	0.115664 (rank : 486)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	453	Target Neighborhood Hits	209	Shared Neighborhood Hits	135
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADA28_MOUSE
NC score	0.115659 (rank : 487)	θ value	0.0193708 (rank : 226)
Query Neighborhood Hits	453	Target Neighborhood Hits	241	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

LRP6_MOUSE
NC score	0.115447 (rank : 488)	θ value	2.36792 (rank : 383)
Query Neighborhood Hits	453	Target Neighborhood Hits	232	Shared Neighborhood Hits	98
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

TARSH_HUMAN
NC score	0.114346 (rank : 489)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	453	Target Neighborhood Hits	768	Shared Neighborhood Hits	106
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

ADA19_HUMAN
NC score	0.113083 (rank : 490)	θ value	0.279714 (rank : 303)
Query Neighborhood Hits	453	Target Neighborhood Hits	381	Shared Neighborhood Hits	149
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
NC score	0.112913 (rank : 491)	θ value	0.21417 (rank : 287)
Query Neighborhood Hits	453	Target Neighborhood Hits	315	Shared Neighborhood Hits	162
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

MUC13_MOUSE
NC score	0.112738 (rank : 492)	θ value	4.03905 (rank : 415)
Query Neighborhood Hits	453	Target Neighborhood Hits	447	Shared Neighborhood Hits	131
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ITLN2_HUMAN
NC score	0.112653 (rank : 493)	θ value	0.365318 (rank : 316)
Query Neighborhood Hits	453	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WWU7	Gene names	ITLN2
Domain Architecture	No domain graphic available
Description	Intelectin-2 precursor (Endothelial lectin HL-2).

ADA33_MOUSE
NC score	0.112411 (rank : 494)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	136
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA10_MOUSE
NC score	0.112285 (rank : 495)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	105
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

CRLF1_MOUSE
NC score	0.112014 (rank : 496)	θ value	0.00390308 (rank : 200)
Query Neighborhood Hits	453	Target Neighborhood Hits	116	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

ADAM9_HUMAN
NC score	0.111995 (rank : 497)	θ value	0.279714 (rank : 305)
Query Neighborhood Hits	453	Target Neighborhood Hits	243	Shared Neighborhood Hits	142
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

FA12_HUMAN
NC score	0.111588 (rank : 498)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	453	Target Neighborhood Hits	425	Shared Neighborhood Hits	157
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

CRLF1_HUMAN
NC score	0.111302 (rank : 499)	θ value	0.00509761 (rank : 204)
Query Neighborhood Hits	453	Target Neighborhood Hits	122	Shared Neighborhood Hits	67
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

ADA10_HUMAN
NC score	0.111264 (rank : 500)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	453	Target Neighborhood Hits	189	Shared Neighborhood Hits	110
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

LRP5_HUMAN
NC score	0.110304 (rank : 501)	θ value	4.03905 (rank : 412)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	101
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

OPCM_HUMAN
NC score	0.110226 (rank : 502)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	68
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

NEGR1_HUMAN
NC score	0.109921 (rank : 503)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	453	Target Neighborhood Hits	346	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

LRP5_MOUSE
NC score	0.109596 (rank : 504)	θ value	4.03905 (rank : 413)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	106
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LSAMP_MOUSE
NC score	0.109556 (rank : 505)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	453	Target Neighborhood Hits	344	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

FAT2_HUMAN
NC score	0.108931 (rank : 506)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	453	Target Neighborhood Hits	507	Shared Neighborhood Hits	163
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

ADA32_HUMAN
NC score	0.108829 (rank : 507)	θ value	0.279714 (rank : 304)
Query Neighborhood Hits	453	Target Neighborhood Hits	216	Shared Neighborhood Hits	136
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

NEGR1_MOUSE
NC score	0.108510 (rank : 508)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	453	Target Neighborhood Hits	349	Shared Neighborhood Hits	64
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

LSAMP_HUMAN
NC score	0.108460 (rank : 509)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	453	Target Neighborhood Hits	347	Shared Neighborhood Hits	66
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

NPTN_HUMAN
NC score	0.107947 (rank : 510)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	453	Target Neighborhood Hits	212	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

KIRR2_HUMAN
NC score	0.107614 (rank : 511)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	453	Target Neighborhood Hits	321	Shared Neighborhood Hits	60
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

ADA33_HUMAN
NC score	0.107295 (rank : 512)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

KIRR2_MOUSE
NC score	0.107249 (rank : 513)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

CI094_HUMAN
NC score	0.106821 (rank : 514)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

NRX1A_HUMAN
NC score	0.106260 (rank : 515)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	453	Target Neighborhood Hits	170	Shared Neighborhood Hits	99
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

ICAM5_MOUSE
NC score	0.106061 (rank : 516)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	67
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

PGCB_MOUSE
NC score	0.106006 (rank : 517)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	453	Target Neighborhood Hits	459	Shared Neighborhood Hits	144
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

LORI_MOUSE
NC score	0.105900 (rank : 518)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

ELTD1_HUMAN
NC score	0.105859 (rank : 519)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

MUC18_HUMAN
NC score	0.105825 (rank : 520)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	453	Target Neighborhood Hits	275	Shared Neighborhood Hits	63
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

PTPRZ_HUMAN
NC score	0.105729 (rank : 521)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	453	Target Neighborhood Hits	255	Shared Neighborhood Hits	42
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

NRX1A_MOUSE
NC score	0.105264 (rank : 522)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	98
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

VCAM1_MOUSE
NC score	0.105034 (rank : 523)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	453	Target Neighborhood Hits	320	Shared Neighborhood Hits	63
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

FSTL4_MOUSE
NC score	0.104932 (rank : 524)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	453	Target Neighborhood Hits	333	Shared Neighborhood Hits	76
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

MAG_MOUSE
NC score	0.104629 (rank : 525)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_HUMAN
NC score	0.104466 (rank : 526)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

TMIGD_HUMAN
NC score	0.104378 (rank : 527)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	453	Target Neighborhood Hits	240	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

JAM3_HUMAN
NC score	0.104369 (rank : 528)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

FSTL4_HUMAN
NC score	0.103821 (rank : 529)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	453	Target Neighborhood Hits	344	Shared Neighborhood Hits	75
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

NTRI_MOUSE
NC score	0.103803 (rank : 530)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	453	Target Neighborhood Hits	342	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NRX2A_HUMAN
NC score	0.103780 (rank : 531)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	453	Target Neighborhood Hits	614	Shared Neighborhood Hits	119
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

FA10_HUMAN
NC score	0.103549 (rank : 532)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	166
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FSTL5_HUMAN
NC score	0.103429 (rank : 533)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	453	Target Neighborhood Hits	347	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

TMIGD_MOUSE
NC score	0.103302 (rank : 534)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	453	Target Neighborhood Hits	234	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

NTRI_HUMAN
NC score	0.102904 (rank : 535)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	453	Target Neighborhood Hits	344	Shared Neighborhood Hits	66
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

ICAM5_HUMAN
NC score	0.102864 (rank : 536)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

FSTL5_MOUSE
NC score	0.102822 (rank : 537)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	453	Target Neighborhood Hits	355	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

ADA24_MOUSE
NC score	0.102742 (rank : 538)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	142
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

RECK_HUMAN
NC score	0.102487 (rank : 539)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	453	Target Neighborhood Hits	189	Shared Neighborhood Hits	101
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

IBP7_MOUSE
NC score	0.102297 (rank : 540)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	71
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ADA17_HUMAN
NC score	0.102185 (rank : 541)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	453	Target Neighborhood Hits	223	Shared Neighborhood Hits	117
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

RAGE_HUMAN
NC score	0.102180 (rank : 542)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	64
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

FA10_MOUSE
NC score	0.102152 (rank : 543)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	453	Target Neighborhood Hits	435	Shared Neighborhood Hits	168
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

RAGE_MOUSE
NC score	0.102110 (rank : 544)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	453	Target Neighborhood Hits	295	Shared Neighborhood Hits	65
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

VCAM1_HUMAN
NC score	0.101877 (rank : 545)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	453	Target Neighborhood Hits	352	Shared Neighborhood Hits	64
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

CT127_HUMAN
NC score	0.101746 (rank : 546)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

NPTN_MOUSE
NC score	0.101218 (rank : 547)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	453	Target Neighborhood Hits	216	Shared Neighborhood Hits	61
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

IBP7_HUMAN
NC score	0.101026 (rank : 548)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	453	Target Neighborhood Hits	220	Shared Neighborhood Hits	69
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

JAM3_MOUSE
NC score	0.100856 (rank : 549)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	453	Target Neighborhood Hits	286	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

SN_MOUSE
NC score	0.100833 (rank : 550)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	453	Target Neighborhood Hits	416	Shared Neighborhood Hits	68
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

ADAM2_HUMAN
NC score	0.100067 (rank : 551)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	113
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

CORIN_HUMAN
NC score	0.100008 (rank : 552)	θ value	3.0926 (rank : 388)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

UROL1_HUMAN
NC score	0.099986 (rank : 553)	θ value	4.03905 (rank : 416)
Query Neighborhood Hits	453	Target Neighborhood Hits	213	Shared Neighborhood Hits	87
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

LRIG1_HUMAN
NC score	0.099857 (rank : 554)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	453	Target Neighborhood Hits	654	Shared Neighborhood Hits	79
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

ADM1B_MOUSE
NC score	0.099679 (rank : 555)	θ value	0.0736092 (rank : 257)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

LRIG2_MOUSE
NC score	0.099498 (rank : 556)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	453	Target Neighborhood Hits	586	Shared Neighborhood Hits	83
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

PTPRE_MOUSE
NC score	0.099493 (rank : 557)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	453	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

COCH_HUMAN
NC score	0.099416 (rank : 558)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	453	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

LRIG2_HUMAN
NC score	0.099413 (rank : 559)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	453	Target Neighborhood Hits	595	Shared Neighborhood Hits	82
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

CO6_HUMAN
NC score	0.099409 (rank : 560)	θ value	8.99809 (rank : 439)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	132
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

LU_HUMAN
NC score	0.099407 (rank : 561)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	453	Target Neighborhood Hits	283	Shared Neighborhood Hits	65
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

LRIG1_MOUSE
NC score	0.099401 (rank : 562)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	453	Target Neighborhood Hits	627	Shared Neighborhood Hits	79
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

PTPRE_HUMAN
NC score	0.099362 (rank : 563)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	453	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.099311 (rank : 564)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	453	Target Neighborhood Hits	101	Shared Neighborhood Hits	19
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PGCB_HUMAN
NC score	0.099236 (rank : 565)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	453	Target Neighborhood Hits	478	Shared Neighborhood Hits	141
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

ESM1_MOUSE
NC score	0.099085 (rank : 566)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	453	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

PTPRA_MOUSE
NC score	0.098872 (rank : 567)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	453	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

ADA18_HUMAN
NC score	0.098713 (rank : 568)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	453	Target Neighborhood Hits	184	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA12_HUMAN
NC score	0.098651 (rank : 569)	θ value	0.62314 (rank : 321)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	117
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

COCH_MOUSE
NC score	0.098635 (rank : 570)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	453	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

MUC18_MOUSE
NC score	0.098620 (rank : 571)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

VITRN_HUMAN
NC score	0.098450 (rank : 572)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	453	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

VITRN_MOUSE
NC score	0.097703 (rank : 573)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	453	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

CORIN_MOUSE
NC score	0.097591 (rank : 574)	θ value	0.0193708 (rank : 228)
Query Neighborhood Hits	453	Target Neighborhood Hits	451	Shared Neighborhood Hits	157
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LRIG3_MOUSE
NC score	0.097380 (rank : 575)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	453	Target Neighborhood Hits	611	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

WFDC3_HUMAN
NC score	0.097362 (rank : 576)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	453	Target Neighborhood Hits	138	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

KIRR1_HUMAN
NC score	0.097232 (rank : 577)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	453	Target Neighborhood Hits	401	Shared Neighborhood Hits	63
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

ADM1A_MOUSE
NC score	0.097173 (rank : 578)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	142
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

SN_HUMAN
NC score	0.096770 (rank : 579)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	453	Target Neighborhood Hits	434	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

LRIG3_HUMAN
NC score	0.096736 (rank : 580)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	453	Target Neighborhood Hits	601	Shared Neighborhood Hits	84
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

PTPRG_HUMAN
NC score	0.096405 (rank : 581)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	49
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

CO6A3_HUMAN
NC score	0.096313 (rank : 582)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	27
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

EPHB4_HUMAN
NC score	0.096233 (rank : 583)	θ value	1.38821 (rank : 362)
Query Neighborhood Hits	453	Target Neighborhood Hits	1056	Shared Neighborhood Hits	196
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

MUC2_HUMAN
NC score	0.096090 (rank : 584)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	153
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

KIRR3_HUMAN
NC score	0.096014 (rank : 585)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	453	Target Neighborhood Hits	302	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

EPHB6_HUMAN
NC score	0.095863 (rank : 586)	θ value	0.0431538 (rank : 244)
Query Neighborhood Hits	453	Target Neighborhood Hits	912	Shared Neighborhood Hits	157
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

PTPRG_MOUSE
NC score	0.095832 (rank : 587)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	453	Target Neighborhood Hits	260	Shared Neighborhood Hits	48
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

KIRR1_MOUSE
NC score	0.095827 (rank : 588)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	453	Target Neighborhood Hits	403	Shared Neighborhood Hits	62
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

NRX3A_HUMAN
NC score	0.095808 (rank : 589)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

CD22_MOUSE
NC score	0.095389 (rank : 590)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	57
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

HCFC2_HUMAN
NC score	0.094868 (rank : 591)	θ value	5.27518 (rank : 420)
Query Neighborhood Hits	453	Target Neighborhood Hits	154	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

MMRN1_HUMAN
NC score	0.094840 (rank : 592)	θ value	6.88961 (rank : 434)
Query Neighborhood Hits	453	Target Neighborhood Hits	636	Shared Neighborhood Hits	112
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

JAM1_HUMAN
NC score	0.094834 (rank : 593)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

BASI_HUMAN
NC score	0.094745 (rank : 594)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	57
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

FA9_HUMAN
NC score	0.094417 (rank : 595)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	453	Target Neighborhood Hits	421	Shared Neighborhood Hits	159
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

KIRR3_MOUSE
NC score	0.094379 (rank : 596)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

PROC_HUMAN
NC score	0.094293 (rank : 597)	θ value	0.813845 (rank : 343)
Query Neighborhood Hits	453	Target Neighborhood Hits	406	Shared Neighborhood Hits	167
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

ADAM7_HUMAN
NC score	0.094026 (rank : 598)	θ value	2.36792 (rank : 375)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	145
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

PGCA_HUMAN
NC score	0.093678 (rank : 599)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	453	Target Neighborhood Hits	821	Shared Neighborhood Hits	151
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PCSK5_HUMAN
NC score	0.093153 (rank : 600)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	453	Target Neighborhood Hits	291	Shared Neighborhood Hits	139
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

KRA24_HUMAN
NC score	0.092775 (rank : 601)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	453	Target Neighborhood Hits	192	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

TYRO3_HUMAN
NC score	0.092708 (rank : 602)	θ value	0.0431538 (rank : 248)
Query Neighborhood Hits	453	Target Neighborhood Hits	995	Shared Neighborhood Hits	112
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

MT4_HUMAN
NC score	0.092631 (rank : 603)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	453	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

BASI_MOUSE
NC score	0.092032 (rank : 604)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	453	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

LRFN4_HUMAN
NC score	0.091863 (rank : 605)	θ value	2.36792 (rank : 381)
Query Neighborhood Hits	453	Target Neighborhood Hits	462	Shared Neighborhood Hits	87
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

JAM1_MOUSE
NC score	0.091453 (rank : 606)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	61
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

ADA12_MOUSE
NC score	0.091398 (rank : 607)	θ value	0.365318 (rank : 312)
Query Neighborhood Hits	453	Target Neighborhood Hits	474	Shared Neighborhood Hits	113
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

MT2_MOUSE
NC score	0.090726 (rank : 608)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	453	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

FCRL2_HUMAN
NC score	0.090350 (rank : 609)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	453	Target Neighborhood Hits	251	Shared Neighborhood Hits	54
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

EPHB4_MOUSE
NC score	0.090130 (rank : 610)	θ value	0.365318 (rank : 313)
Query Neighborhood Hits	453	Target Neighborhood Hits	1013	Shared Neighborhood Hits	180
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHB6_MOUSE
NC score	0.089716 (rank : 611)	θ value	0.163984 (rank : 280)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	141
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

PTK7_HUMAN
NC score	0.089664 (rank : 612)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	453	Target Neighborhood Hits	1103	Shared Neighborhood Hits	95
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

EPHA7_HUMAN
NC score	0.089513 (rank : 613)	θ value	1.06291 (rank : 353)
Query Neighborhood Hits	453	Target Neighborhood Hits	1053	Shared Neighborhood Hits	189
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

VEGFC_MOUSE
NC score	0.089438 (rank : 614)	θ value	1.81305 (rank : 374)
Query Neighborhood Hits	453	Target Neighborhood Hits	119	Shared Neighborhood Hits	80
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

FCRL5_HUMAN
NC score	0.089392 (rank : 615)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	453	Target Neighborhood Hits	267	Shared Neighborhood Hits	54
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

CNTP2_MOUSE
NC score	0.089147 (rank : 616)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	104
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

MT1B_HUMAN
NC score	0.089141 (rank : 617)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	453	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

UROL1_MOUSE
NC score	0.088955 (rank : 618)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	102
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ITLN1_HUMAN
NC score	0.088547 (rank : 619)	θ value	0.813845 (rank : 337)
Query Neighborhood Hits	453	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WWA0, Q6YDJ3, Q9NP67	Gene names	ITLN1, INTL, ITLN, LFR
Domain Architecture	No domain graphic available
Description	Intelectin-1 precursor (Intestinal lactoferrin receptor) (Galactofuranose-binding lectin) (Endothelial lectin HL-1) (Omentin).

CD22_HUMAN
NC score	0.088172 (rank : 620)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	60
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

BMPER_MOUSE
NC score	0.088023 (rank : 621)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

COJA1_HUMAN
NC score	0.087722 (rank : 622)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	453	Target Neighborhood Hits	323	Shared Neighborhood Hits	19
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CNTP2_HUMAN
NC score	0.087538 (rank : 623)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

ADA30_HUMAN
NC score	0.087383 (rank : 624)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	453	Target Neighborhood Hits	391	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA17_MOUSE
NC score	0.087173 (rank : 625)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	453	Target Neighborhood Hits	201	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

FA7_HUMAN
NC score	0.086862 (rank : 626)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	453	Target Neighborhood Hits	404	Shared Neighborhood Hits	154
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

EPHA7_MOUSE
NC score	0.086804 (rank : 627)	θ value	2.36792 (rank : 376)
Query Neighborhood Hits	453	Target Neighborhood Hits	1025	Shared Neighborhood Hits	167
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

TYRO3_MOUSE
NC score	0.086678 (rank : 628)	θ value	0.813845 (rank : 348)
Query Neighborhood Hits	453	Target Neighborhood Hits	1007	Shared Neighborhood Hits	115
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

PTN7_HUMAN
NC score	0.086494 (rank : 629)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	17
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN9_MOUSE
NC score	0.086322 (rank : 630)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	453	Target Neighborhood Hits	78	Shared Neighborhood Hits	17
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_HUMAN
NC score	0.086281 (rank : 631)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	17
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN7_MOUSE
NC score	0.086201 (rank : 632)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	453	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

JAM2_HUMAN
NC score	0.086184 (rank : 633)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	453	Target Neighborhood Hits	304	Shared Neighborhood Hits	65
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

APR3_MOUSE
NC score	0.086114 (rank : 634)	θ value	8.99809 (rank : 437)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

LRC21_MOUSE
NC score	0.085675 (rank : 635)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	453	Target Neighborhood Hits	462	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

ADAM7_MOUSE
NC score	0.085594 (rank : 636)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	453	Target Neighborhood Hits	200	Shared Neighborhood Hits	120
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

CONA1_HUMAN
NC score	0.085588 (rank : 637)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	453	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CEAM5_HUMAN
NC score	0.085561 (rank : 638)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	65
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

ADA25_MOUSE
NC score	0.085551 (rank : 639)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	453	Target Neighborhood Hits	213	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

PTN2_HUMAN
NC score	0.085366 (rank : 640)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	453	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

LRC21_HUMAN
NC score	0.085307 (rank : 641)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

PTN2_MOUSE
NC score	0.085146 (rank : 642)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	453	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

CO8B_MOUSE
NC score	0.085089 (rank : 643)	θ value	4.03905 (rank : 407)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

VSIG2_HUMAN
NC score	0.085051 (rank : 644)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	453	Target Neighborhood Hits	321	Shared Neighborhood Hits	62
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

PTN1_HUMAN
NC score	0.085038 (rank : 645)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	453	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

EPHB3_MOUSE
NC score	0.084929 (rank : 646)	θ value	0.0961366 (rank : 263)
Query Neighborhood Hits	453	Target Neighborhood Hits	996	Shared Neighborhood Hits	142
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

PTN1_MOUSE
NC score	0.084705 (rank : 647)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN18_MOUSE
NC score	0.084648 (rank : 648)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	453	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

EPHB3_HUMAN
NC score	0.084642 (rank : 649)	θ value	0.62314 (rank : 322)
Query Neighborhood Hits	453	Target Neighborhood Hits	996	Shared Neighborhood Hits	147
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHA2_HUMAN
NC score	0.084552 (rank : 650)	θ value	0.0330416 (rank : 240)
Query Neighborhood Hits	453	Target Neighborhood Hits	1021	Shared Neighborhood Hits	151
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

COGA1_HUMAN
NC score	0.084510 (rank : 651)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	453	Target Neighborhood Hits	345	Shared Neighborhood Hits	34
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

EPHA4_MOUSE
NC score	0.084496 (rank : 652)	θ value	0.125558 (rank : 270)
Query Neighborhood Hits	453	Target Neighborhood Hits	982	Shared Neighborhood Hits	148
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

PTN5_HUMAN
NC score	0.084297 (rank : 653)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	453	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
NC score	0.084178 (rank : 654)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRR_HUMAN
NC score	0.084153 (rank : 655)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	453	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

CNTP1_HUMAN
NC score	0.084077 (rank : 656)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

LRP10_HUMAN
NC score	0.083931 (rank : 657)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	453	Target Neighborhood Hits	197	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

PTPRR_MOUSE
NC score	0.083898 (rank : 658)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	453	Target Neighborhood Hits	84	Shared Neighborhood Hits	18
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

MUSK_MOUSE
NC score	0.083886 (rank : 659)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	453	Target Neighborhood Hits	1057	Shared Neighborhood Hits	95
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

IGS4B_MOUSE
NC score	0.083685 (rank : 660)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	453	Target Neighborhood Hits	328	Shared Neighborhood Hits	60
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

EPHA4_HUMAN
NC score	0.083636 (rank : 661)	θ value	0.0961366 (rank : 261)
Query Neighborhood Hits	453	Target Neighborhood Hits	975	Shared Neighborhood Hits	142
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

IGS4B_HUMAN
NC score	0.083607 (rank : 662)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	453	Target Neighborhood Hits	305	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

CO7_HUMAN
NC score	0.083605 (rank : 663)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	121
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

MFA3L_HUMAN
NC score	0.083536 (rank : 664)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	62
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

MUSK_HUMAN
NC score	0.083452 (rank : 665)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	453	Target Neighborhood Hits	1074	Shared Neighborhood Hits	95
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

CNTP4_MOUSE
NC score	0.083439 (rank : 666)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	107
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

PTN18_HUMAN
NC score	0.083437 (rank : 667)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN22_HUMAN
NC score	0.083209 (rank : 668)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	453	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

EPHA3_MOUSE
NC score	0.082966 (rank : 669)	θ value	0.813845 (rank : 333)
Query Neighborhood Hits	453	Target Neighborhood Hits	1009	Shared Neighborhood Hits	168
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA2_MOUSE
NC score	0.082690 (rank : 670)	θ value	0.279714 (rank : 308)
Query Neighborhood Hits	453	Target Neighborhood Hits	1020	Shared Neighborhood Hits	154
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

CNTP1_MOUSE
NC score	0.082676 (rank : 671)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	453	Target Neighborhood Hits	183	Shared Neighborhood Hits	94
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

PTPRN_HUMAN
NC score	0.082489 (rank : 672)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPR2_MOUSE
NC score	0.082470 (rank : 673)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

JAM2_MOUSE
NC score	0.082275 (rank : 674)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

PTPR2_HUMAN
NC score	0.082190 (rank : 675)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	18
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

LCE4A_HUMAN
NC score	0.082182 (rank : 676)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	453	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

PTN12_HUMAN
NC score	0.082073 (rank : 677)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

ATL3_HUMAN
NC score	0.081979 (rank : 678)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	453	Target Neighborhood Hits	414	Shared Neighborhood Hits	103
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

PTPRN_MOUSE
NC score	0.081628 (rank : 679)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	453	Target Neighborhood Hits	240	Shared Neighborhood Hits	27
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

CEA20_HUMAN
NC score	0.081482 (rank : 680)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	453	Target Neighborhood Hits	251	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

I27RA_HUMAN
NC score	0.081450 (rank : 681)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	453	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

PRPE_HUMAN
NC score	0.081097 (rank : 682)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PTN12_MOUSE
NC score	0.081069 (rank : 683)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	453	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN22_MOUSE
NC score	0.080938 (rank : 684)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	453	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

EPHA5_HUMAN
NC score	0.080879 (rank : 685)	θ value	5.27518 (rank : 419)
Query Neighborhood Hits	453	Target Neighborhood Hits	1009	Shared Neighborhood Hits	155
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

CEAM1_MOUSE
NC score	0.080871 (rank : 686)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	64
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

LRFN4_MOUSE
NC score	0.080572 (rank : 687)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	453	Target Neighborhood Hits	442	Shared Neighborhood Hits	81
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRRN1_HUMAN
NC score	0.080468 (rank : 688)	θ value	0.62314 (rank : 324)
Query Neighborhood Hits	453	Target Neighborhood Hits	518	Shared Neighborhood Hits	88
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

EPHA6_HUMAN
NC score	0.080462 (rank : 689)	θ value	0.00035302 (rank : 176)
Query Neighborhood Hits	453	Target Neighborhood Hits	959	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

CNTP3_HUMAN
NC score	0.080247 (rank : 690)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	453	Target Neighborhood Hits	195	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
NC score	0.080187 (rank : 691)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	453	Target Neighborhood Hits	187	Shared Neighborhood Hits	91
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

SIG11_HUMAN
NC score	0.079856 (rank : 692)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	453	Target Neighborhood Hits	273	Shared Neighborhood Hits	64
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

CONA1_MOUSE
NC score	0.079769 (rank : 693)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	453	Target Neighborhood Hits	254	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

APR3_HUMAN
NC score	0.079742 (rank : 694)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

UFO_MOUSE
NC score	0.079706 (rank : 695)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	453	Target Neighborhood Hits	988	Shared Neighborhood Hits	120
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

EPHB2_HUMAN
NC score	0.079215 (rank : 696)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	453	Target Neighborhood Hits	983	Shared Neighborhood Hits	146
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHA3_HUMAN
NC score	0.079212 (rank : 697)	θ value	1.38821 (rank : 361)
Query Neighborhood Hits	453	Target Neighborhood Hits	1005	Shared Neighborhood Hits	167
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

LRRN1_MOUSE
NC score	0.079175 (rank : 698)	θ value	0.0563607 (rank : 251)
Query Neighborhood Hits	453	Target Neighborhood Hits	508	Shared Neighborhood Hits	85
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

EPHB2_MOUSE
NC score	0.079068 (rank : 699)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	453	Target Neighborhood Hits	982	Shared Neighborhood Hits	146
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

SIG10_HUMAN
NC score	0.079004 (rank : 700)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	453	Target Neighborhood Hits	363	Shared Neighborhood Hits	64
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

PCSK6_HUMAN
NC score	0.078982 (rank : 701)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	123
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

RECK_MOUSE
NC score	0.078502 (rank : 702)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	453	Target Neighborhood Hits	158	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

MERTK_HUMAN
NC score	0.078500 (rank : 703)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	453	Target Neighborhood Hits	988	Shared Neighborhood Hits	109
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
NC score	0.078473 (rank : 704)	θ value	0.0330416 (rank : 242)
Query Neighborhood Hits	453	Target Neighborhood Hits	974	Shared Neighborhood Hits	113
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

ADA21_MOUSE
NC score	0.078377 (rank : 705)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

EPHAA_HUMAN
NC score	0.078309 (rank : 706)	θ value	0.0961366 (rank : 262)
Query Neighborhood Hits	453	Target Neighborhood Hits	960	Shared Neighborhood Hits	133
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

LRFN3_MOUSE
NC score	0.078259 (rank : 707)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

VASN_HUMAN
NC score	0.077708 (rank : 708)	θ value	0.47712 (rank : 319)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	120
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VSIG2_MOUSE
NC score	0.077551 (rank : 709)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	453	Target Neighborhood Hits	316	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

CO9A3_HUMAN
NC score	0.077398 (rank : 710)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	14
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

MT1A_HUMAN
NC score	0.077199 (rank : 711)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	453	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

CD320_HUMAN
NC score	0.077044 (rank : 712)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

AD26A_MOUSE
NC score	0.076974 (rank : 713)	θ value	0.163984 (rank : 277)
Query Neighborhood Hits	453	Target Neighborhood Hits	165	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

LRFN2_MOUSE
NC score	0.076858 (rank : 714)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	453	Target Neighborhood Hits	450	Shared Neighborhood Hits	80
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

PTN6_HUMAN
NC score	0.076722 (rank : 715)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	453	Target Neighborhood Hits	234	Shared Neighborhood Hits	18
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

EPHB1_HUMAN
NC score	0.076618 (rank : 716)	θ value	0.813845 (rank : 334)
Query Neighborhood Hits	453	Target Neighborhood Hits	988	Shared Neighborhood Hits	151
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

LRP3_HUMAN
NC score	0.076614 (rank : 717)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	94
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ADA29_HUMAN
NC score	0.076583 (rank : 718)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

PTN6_MOUSE
NC score	0.076540 (rank : 719)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

LRFN2_HUMAN
NC score	0.076402 (rank : 720)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	453	Target Neighborhood Hits	450	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

EPHA8_MOUSE
NC score	0.076356 (rank : 721)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	453	Target Neighborhood Hits	969	Shared Neighborhood Hits	136
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

MKS3_MOUSE
NC score	0.076206 (rank : 722)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	453	Target Neighborhood Hits	89	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

EPHA8_HUMAN
NC score	0.076105 (rank : 723)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	453	Target Neighborhood Hits	956	Shared Neighborhood Hits	132
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

CO4A4_HUMAN
NC score	0.075513 (rank : 724)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	22
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO9A1_HUMAN
NC score	0.075507 (rank : 725)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	453	Target Neighborhood Hits	420	Shared Neighborhood Hits	22
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

ROS_HUMAN
NC score	0.075189 (rank : 726)	θ value	3.0926 (rank : 401)
Query Neighborhood Hits	453	Target Neighborhood Hits	907	Shared Neighborhood Hits	135
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

PGH2_MOUSE
NC score	0.075153 (rank : 727)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

ANKF1_HUMAN
NC score	0.075113 (rank : 728)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

MUC13_HUMAN
NC score	0.075049 (rank : 729)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MFA3L_MOUSE
NC score	0.074732 (rank : 730)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	453	Target Neighborhood Hits	214	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

ADA21_HUMAN
NC score	0.074530 (rank : 731)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	453	Target Neighborhood Hits	181	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

PTN11_HUMAN
NC score	0.074516 (rank : 732)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	453	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.074481 (rank : 733)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	453	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

UFO_HUMAN
NC score	0.074473 (rank : 734)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	453	Target Neighborhood Hits	981	Shared Neighborhood Hits	117
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

CO5A2_HUMAN
NC score	0.074381 (rank : 735)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	453	Target Neighborhood Hits	760	Shared Neighborhood Hits	52
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

PERT_HUMAN
NC score	0.074232 (rank : 736)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	91
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

EPHA6_MOUSE
NC score	0.073986 (rank : 737)	θ value	0.00134147 (rank : 191)
Query Neighborhood Hits	453	Target Neighborhood Hits	946	Shared Neighborhood Hits	129
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

MT1H_HUMAN
NC score	0.073979 (rank : 738)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	453	Target Neighborhood Hits	78	Shared Neighborhood Hits	42
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

CO9A1_MOUSE
NC score	0.073976 (rank : 739)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	453	Target Neighborhood Hits	477	Shared Neighborhood Hits	18
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

LRRN3_HUMAN
NC score	0.073921 (rank : 740)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	453	Target Neighborhood Hits	461	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRFN3_HUMAN
NC score	0.073865 (rank : 741)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

FSTL3_HUMAN
NC score	0.073689 (rank : 742)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	86
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

KR124_HUMAN
NC score	0.073262 (rank : 743)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	453	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

CO4A3_HUMAN
NC score	0.073146 (rank : 744)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	453	Target Neighborhood Hits	421	Shared Neighborhood Hits	23
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

MFGM_HUMAN
NC score	0.073031 (rank : 745)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	453	Target Neighborhood Hits	150	Shared Neighborhood Hits	86
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MARCO_MOUSE
NC score	0.072712 (rank : 746)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	453	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

CO9A2_MOUSE
NC score	0.072564 (rank : 747)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	453	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO9A2_HUMAN
NC score	0.072463 (rank : 748)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	13
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

NRG4_HUMAN
NC score	0.072386 (rank : 749)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

EMR3_HUMAN
NC score	0.072308 (rank : 750)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

VASN_MOUSE
NC score	0.072307 (rank : 751)	θ value	3.0926 (rank : 404)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	116
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

CO6A1_HUMAN
NC score	0.072247 (rank : 752)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	14
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

OBSCN_HUMAN
NC score	0.072131 (rank : 753)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	453	Target Neighborhood Hits	1931	Shared Neighborhood Hits	130
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

FA7_MOUSE
NC score	0.072088 (rank : 754)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	453	Target Neighborhood Hits	374	Shared Neighborhood Hits	131
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

COBA2_MOUSE
NC score	0.071851 (rank : 755)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	453	Target Neighborhood Hits	501	Shared Neighborhood Hits	26
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CEAM1_HUMAN
NC score	0.071830 (rank : 756)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	453	Target Neighborhood Hits	348	Shared Neighborhood Hits	62
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

PTN23_MOUSE
NC score	0.071206 (rank : 757)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	453	Target Neighborhood Hits	726	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

LRP10_MOUSE
NC score	0.071095 (rank : 758)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	453	Target Neighborhood Hits	169	Shared Neighborhood Hits	71
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

BMPER_HUMAN
NC score	0.070592 (rank : 759)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CO5A3_HUMAN
NC score	0.070361 (rank : 760)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	453	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO4A2_HUMAN
NC score	0.069601 (rank : 761)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	453	Target Neighborhood Hits	454	Shared Neighborhood Hits	17
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A1_HUMAN
NC score	0.069475 (rank : 762)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	453	Target Neighborhood Hits	425	Shared Neighborhood Hits	19
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

COBA1_MOUSE
NC score	0.069227 (rank : 763)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	453	Target Neighborhood Hits	487	Shared Neighborhood Hits	24
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO4A1_MOUSE
NC score	0.069161 (rank : 764)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	453	Target Neighborhood Hits	450	Shared Neighborhood Hits	18
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

PTN23_HUMAN
NC score	0.069126 (rank : 765)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	453	Target Neighborhood Hits	646	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CTHR1_MOUSE
NC score	0.068589 (rank : 766)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	453	Target Neighborhood Hits	123	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

SMDF_HUMAN
NC score	0.068462 (rank : 767)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	453	Target Neighborhood Hits	117	Shared Neighborhood Hits	58
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

COBA2_HUMAN
NC score	0.068362 (rank : 768)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	453	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COBA1_HUMAN
NC score	0.068230 (rank : 769)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	453	Target Neighborhood Hits	491	Shared Neighborhood Hits	27
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

VGFR1_HUMAN
NC score	0.068184 (rank : 770)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	453	Target Neighborhood Hits	1109	Shared Neighborhood Hits	93
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

VGFR1_MOUSE
NC score	0.068133 (rank : 771)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	453	Target Neighborhood Hits	1118	Shared Neighborhood Hits	95
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

MYLK_MOUSE
NC score	0.067546 (rank : 772)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	453	Target Neighborhood Hits	1489	Shared Neighborhood Hits	117
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYLK_HUMAN
NC score	0.067461 (rank : 773)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	453	Target Neighborhood Hits	1328	Shared Neighborhood Hits	115
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MT1_MOUSE
NC score	0.067445 (rank : 774)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	453	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MKS3_HUMAN
NC score	0.067400 (rank : 775)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	58
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

LCE2C_HUMAN
NC score	0.067358 (rank : 776)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

FSTL3_MOUSE
NC score	0.067327 (rank : 777)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	453	Target Neighborhood Hits	152	Shared Neighborhood Hits	84
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

LRRN3_MOUSE
NC score	0.067045 (rank : 778)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

CILP2_HUMAN
NC score	0.066949 (rank : 779)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	453	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CTHR1_HUMAN
NC score	0.066798 (rank : 780)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

PTN14_HUMAN
NC score	0.066676 (rank : 781)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	453	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

CD166_MOUSE
NC score	0.066608 (rank : 782)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	453	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

CO4A2_MOUSE
NC score	0.066596 (rank : 783)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	453	Target Neighborhood Hits	492	Shared Neighborhood Hits	23
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

VSIG4_HUMAN
NC score	0.066471 (rank : 784)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

COLQ_HUMAN
NC score	0.066372 (rank : 785)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

CO4A6_HUMAN
NC score	0.066335 (rank : 786)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

SPEG_MOUSE
NC score	0.066335 (rank : 787)	θ value	0.365318 (rank : 317)
Query Neighborhood Hits	453	Target Neighborhood Hits	1959	Shared Neighborhood Hits	118
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PTN21_MOUSE
NC score	0.066205 (rank : 788)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

ST14_HUMAN
NC score	0.066137 (rank : 789)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	453	Target Neighborhood Hits	409	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

NRG4_MOUSE
NC score	0.066033 (rank : 790)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

TNR16_HUMAN
NC score	0.066015 (rank : 791)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	453	Target Neighborhood Hits	183	Shared Neighborhood Hits	84
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

PTN14_MOUSE
NC score	0.065984 (rank : 792)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	453	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

TNR25_HUMAN
NC score	0.065787 (rank : 793)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	65
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

INSRR_MOUSE
NC score	0.065625 (rank : 794)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	453	Target Neighborhood Hits	961	Shared Neighborhood Hits	160
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

SPEG_HUMAN
NC score	0.065598 (rank : 795)	θ value	5.27518 (rank : 426)
Query Neighborhood Hits	453	Target Neighborhood Hits	1762	Shared Neighborhood Hits	117
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PTN21_HUMAN
NC score	0.065474 (rank : 796)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

INSRR_HUMAN
NC score	0.065321 (rank : 797)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	453	Target Neighborhood Hits	950	Shared Neighborhood Hits	156
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

PTN3_HUMAN
NC score	0.065249 (rank : 798)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	453	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

UNC5D_MOUSE
NC score	0.065236 (rank : 799)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

IL1R2_HUMAN
NC score	0.065151 (rank : 800)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	44
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

LRFN5_MOUSE
NC score	0.065060 (rank : 801)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	453	Target Neighborhood Hits	472	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

MSRE_HUMAN
NC score	0.064671 (rank : 802)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

EPHA5_MOUSE
NC score	0.064658 (rank : 803)	θ value	0.00390308 (rank : 201)
Query Neighborhood Hits	453	Target Neighborhood Hits	950	Shared Neighborhood Hits	118
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

VGFR2_HUMAN
NC score	0.064572 (rank : 804)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	453	Target Neighborhood Hits	1103	Shared Neighborhood Hits	93
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

TECTA_MOUSE
NC score	0.064308 (rank : 805)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	134
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

PGH2_HUMAN
NC score	0.064307 (rank : 806)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

ST14_MOUSE
NC score	0.064269 (rank : 807)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	135
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

C1QA_HUMAN
NC score	0.064155 (rank : 808)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	453	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

COIA1_MOUSE
NC score	0.064050 (rank : 809)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	453	Target Neighborhood Hits	481	Shared Neighborhood Hits	26
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COAA1_MOUSE
NC score	0.063948 (rank : 810)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	453	Target Neighborhood Hits	286	Shared Neighborhood Hits	19
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

GPA33_MOUSE
NC score	0.063877 (rank : 811)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

SIGL5_MOUSE
NC score	0.063816 (rank : 812)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	56
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

LRFN5_HUMAN
NC score	0.063754 (rank : 813)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	453	Target Neighborhood Hits	464	Shared Neighborhood Hits	74
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

MEP1A_MOUSE
NC score	0.063552 (rank : 814)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	453	Target Neighborhood Hits	166	Shared Neighborhood Hits	90
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

VGFR2_MOUSE
NC score	0.063549 (rank : 815)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	453	Target Neighborhood Hits	1089	Shared Neighborhood Hits	93
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

ASTN_MOUSE
NC score	0.063241 (rank : 816)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	453	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

CO1A2_MOUSE
NC score	0.063234 (rank : 817)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	453	Target Neighborhood Hits	388	Shared Neighborhood Hits	19
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

MCSP_MOUSE
NC score	0.063211 (rank : 818)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	453	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

LCE2D_HUMAN
NC score	0.063165 (rank : 819)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

FGFR4_MOUSE
NC score	0.063124 (rank : 820)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	453	Target Neighborhood Hits	1026	Shared Neighborhood Hits	94
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

ADA20_HUMAN
NC score	0.063101 (rank : 821)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

PTN4_HUMAN
NC score	0.063032 (rank : 822)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	453	Target Neighborhood Hits	303	Shared Neighborhood Hits	21
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PERT_MOUSE
NC score	0.062927 (rank : 823)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	86
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

CO2A1_HUMAN
NC score	0.062871 (rank : 824)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	453	Target Neighborhood Hits	486	Shared Neighborhood Hits	17
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

EPHA1_HUMAN
NC score	0.062706 (rank : 825)	θ value	3.0926 (rank : 393)
Query Neighborhood Hits	453	Target Neighborhood Hits	997	Shared Neighborhood Hits	144
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

FST_MOUSE
NC score	0.062698 (rank : 826)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	453	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

CO6A1_MOUSE
NC score	0.062683 (rank : 827)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	453	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CRAC1_MOUSE
NC score	0.062640 (rank : 828)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

UNC5D_HUMAN
NC score	0.062627 (rank : 829)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	453	Target Neighborhood Hits	267	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

CO8B_HUMAN
NC score	0.062136 (rank : 830)	θ value	6.88961 (rank : 431)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	83
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

GLDN_HUMAN
NC score	0.062085 (rank : 831)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	453	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

CO2A1_MOUSE
NC score	0.062062 (rank : 832)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	453	Target Neighborhood Hits	483	Shared Neighborhood Hits	27
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

INSR_MOUSE
NC score	0.061933 (rank : 833)	θ value	0.0961366 (rank : 264)
Query Neighborhood Hits	453	Target Neighborhood Hits	968	Shared Neighborhood Hits	141
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

FST_HUMAN
NC score	0.061924 (rank : 834)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	453	Target Neighborhood Hits	129	Shared Neighborhood Hits	53
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

CO6A2_MOUSE
NC score	0.061520 (rank : 835)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	453	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

ADIPO_HUMAN
NC score	0.061467 (rank : 836)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	453	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

CEAM6_HUMAN
NC score	0.061461 (rank : 837)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	63
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

INSR_HUMAN
NC score	0.061450 (rank : 838)	θ value	0.279714 (rank : 309)
Query Neighborhood Hits	453	Target Neighborhood Hits	963	Shared Neighborhood Hits	144
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

FGFR4_HUMAN
NC score	0.061447 (rank : 839)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	453	Target Neighborhood Hits	1037	Shared Neighborhood Hits	94
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

TPA_MOUSE
NC score	0.061276 (rank : 840)	θ value	0.813845 (rank : 345)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	121
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

CLC14_MOUSE
NC score	0.061256 (rank : 841)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

LCE2A_HUMAN
NC score	0.061146 (rank : 842)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

CRAC1_HUMAN
NC score	0.061015 (rank : 843)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	453	Target Neighborhood Hits	111	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

TPA_HUMAN
NC score	0.061015 (rank : 844)	θ value	0.813845 (rank : 344)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	119
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

KRA63_HUMAN
NC score	0.060932 (rank : 845)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	453	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

ADIPO_MOUSE
NC score	0.060541 (rank : 846)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	453	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

FGFR3_MOUSE
NC score	0.060498 (rank : 847)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	453	Target Neighborhood Hits	1059	Shared Neighborhood Hits	97
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

ASTN_HUMAN
NC score	0.060434 (rank : 848)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	453	Target Neighborhood Hits	105	Shared Neighborhood Hits	53
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

CO9_MOUSE
NC score	0.060380 (rank : 849)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	78
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CILP1_HUMAN
NC score	0.060189 (rank : 850)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	453	Target Neighborhood Hits	266	Shared Neighborhood Hits	77
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

GPA33_HUMAN
NC score	0.060134 (rank : 851)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	453	Target Neighborhood Hits	273	Shared Neighborhood Hits	51
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

MEP1A_HUMAN
NC score	0.060065 (rank : 852)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	84
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

CO6A2_HUMAN
NC score	0.060025 (rank : 853)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	453	Target Neighborhood Hits	249	Shared Neighborhood Hits	14
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

PGH1_MOUSE
NC score	0.059915 (rank : 854)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

CO8A_HUMAN
NC score	0.059806 (rank : 855)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	453	Target Neighborhood Hits	200	Shared Neighborhood Hits	90
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

COHA1_MOUSE
NC score	0.059778 (rank : 856)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	453	Target Neighborhood Hits	414	Shared Neighborhood Hits	15
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CLC14_HUMAN
NC score	0.059776 (rank : 857)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	66
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CD166_HUMAN
NC score	0.059671 (rank : 858)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	54
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

MT1X_HUMAN
NC score	0.059523 (rank : 859)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	453	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

LCE2B_HUMAN
NC score	0.059480 (rank : 860)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

CO1A2_HUMAN
NC score	0.059219 (rank : 861)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A1_HUMAN
NC score	0.059118 (rank : 862)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	453	Target Neighborhood Hits	475	Shared Neighborhood Hits	44
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

PTN13_MOUSE
NC score	0.059116 (rank : 863)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	24
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

FGFR1_MOUSE
NC score	0.058848 (rank : 864)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	453	Target Neighborhood Hits	1068	Shared Neighborhood Hits	94
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FGFR1_HUMAN
NC score	0.058812 (rank : 865)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	453	Target Neighborhood Hits	1069	Shared Neighborhood Hits	94
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR3_HUMAN
NC score	0.058747 (rank : 866)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	453	Target Neighborhood Hits	1042	Shared Neighborhood Hits	94
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

COIA1_HUMAN
NC score	0.058585 (rank : 867)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	453	Target Neighborhood Hits	447	Shared Neighborhood Hits	23
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

FGFR2_HUMAN
NC score	0.058336 (rank : 868)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	453	Target Neighborhood Hits	1062	Shared Neighborhood Hits	94
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

CO9_HUMAN
NC score	0.058196 (rank : 869)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	453	Target Neighborhood Hits	147	Shared Neighborhood Hits	74
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

PTN13_HUMAN
NC score	0.058163 (rank : 870)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	453	Target Neighborhood Hits	471	Shared Neighborhood Hits	22
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

DUET_HUMAN
NC score	0.058024 (rank : 871)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	453	Target Neighborhood Hits	1220	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

LRRN5_HUMAN
NC score	0.057711 (rank : 872)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	453	Target Neighborhood Hits	493	Shared Neighborhood Hits	76
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

COFA1_MOUSE
NC score	0.057603 (rank : 873)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	453	Target Neighborhood Hits	305	Shared Neighborhood Hits	23
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

HCFC1_MOUSE
NC score	0.057413 (rank : 874)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	453	Target Neighborhood Hits	348	Shared Neighborhood Hits	62
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

ROR2_MOUSE
NC score	0.056967 (rank : 875)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	453	Target Neighborhood Hits	1000	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

IGF1R_HUMAN
NC score	0.056873 (rank : 876)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	453	Target Neighborhood Hits	977	Shared Neighborhood Hits	156
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

EPHA1_MOUSE
NC score	0.056804 (rank : 877)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	453	Target Neighborhood Hits	958	Shared Neighborhood Hits	134
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

IL1R2_MOUSE
NC score	0.056739 (rank : 878)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	40
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IGF1R_MOUSE
NC score	0.056137 (rank : 879)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	453	Target Neighborhood Hits	973	Shared Neighborhood Hits	159
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

CILP1_MOUSE
NC score	0.056015 (rank : 880)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	73
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

SFTPD_HUMAN
NC score	0.056000 (rank : 881)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	453	Target Neighborhood Hits	238	Shared Neighborhood Hits	20
SwissProt Accessions	P35247, Q86YK9, Q9UCJ2, Q9UCJ3	Gene names	SFTPD, PSPD, SFTP4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

FGFR2_MOUSE
NC score	0.055938 (rank : 882)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	453	Target Neighborhood Hits	1062	Shared Neighborhood Hits	93
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

IRPL2_HUMAN
NC score	0.055863 (rank : 883)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

UNC5C_HUMAN
NC score	0.055761 (rank : 884)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	68
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
NC score	0.055683 (rank : 885)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5A_HUMAN
NC score	0.055626 (rank : 886)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	453	Target Neighborhood Hits	198	Shared Neighborhood Hits	61
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

EMR4_MOUSE
NC score	0.055269 (rank : 887)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	73
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

VGFR3_HUMAN
NC score	0.055252 (rank : 888)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	453	Target Neighborhood Hits	1037	Shared Neighborhood Hits	93
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

C1QC_MOUSE
NC score	0.055186 (rank : 889)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	453	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

TNR16_MOUSE
NC score	0.055175 (rank : 890)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

CO4A5_HUMAN
NC score	0.055153 (rank : 891)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	453	Target Neighborhood Hits	383	Shared Neighborhood Hits	19
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

IRPL2_MOUSE
NC score	0.055099 (rank : 892)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	453	Target Neighborhood Hits	195	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

I27RA_MOUSE
NC score	0.055063 (rank : 893)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	453	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

ROR2_HUMAN
NC score	0.055020 (rank : 894)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	453	Target Neighborhood Hits	1014	Shared Neighborhood Hits	101
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

EMID1_MOUSE
NC score	0.055011 (rank : 895)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	12
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

CO8A_MOUSE
NC score	0.054994 (rank : 896)	θ value	1.81305 (rank : 368)
Query Neighborhood Hits	453	Target Neighborhood Hits	182	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

LRP12_HUMAN
NC score	0.054968 (rank : 897)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	453	Target Neighborhood Hits	205	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

DKK3_MOUSE
NC score	0.054880 (rank : 898)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	453	Target Neighborhood Hits	83	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

IRPL1_MOUSE
NC score	0.054871 (rank : 899)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	453	Target Neighborhood Hits	186	Shared Neighborhood Hits	53
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

MARCO_HUMAN
NC score	0.054792 (rank : 900)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

LEPR_HUMAN
NC score	0.054738 (rank : 901)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	50
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

MT1E_HUMAN
NC score	0.054603 (rank : 902)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	42
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

TECTA_HUMAN
NC score	0.054469 (rank : 903)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	453	Target Neighborhood Hits	239	Shared Neighborhood Hits	117
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

MT1F_HUMAN
NC score	0.054411 (rank : 904)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

VGFR3_MOUSE
NC score	0.054287 (rank : 905)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	453	Target Neighborhood Hits	1056	Shared Neighborhood Hits	96
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

EREG_HUMAN
NC score	0.054056 (rank : 906)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	45
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

UNC5B_HUMAN
NC score	0.053907 (rank : 907)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

LRP12_MOUSE
NC score	0.053857 (rank : 908)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

UNC5B_MOUSE
NC score	0.053719 (rank : 909)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

CSF1R_MOUSE
NC score	0.053541 (rank : 910)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	453	Target Neighborhood Hits	983	Shared Neighborhood Hits	86
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

HCFC1_HUMAN
NC score	0.053434 (rank : 911)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	58
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MT1M_HUMAN
NC score	0.053388 (rank : 912)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	453	Target Neighborhood Hits	72	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

ADEC1_MOUSE
NC score	0.053234 (rank : 913)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ROR1_HUMAN
NC score	0.053156 (rank : 914)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	453	Target Neighborhood Hits	1018	Shared Neighborhood Hits	102
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

GLDN_MOUSE
NC score	0.053120 (rank : 915)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

ROR1_MOUSE
NC score	0.052706 (rank : 916)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	453	Target Neighborhood Hits	1025	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

LRC24_HUMAN
NC score	0.052607 (rank : 917)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	453	Target Neighborhood Hits	404	Shared Neighborhood Hits	68
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

CD276_HUMAN
NC score	0.052602 (rank : 918)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

ZNFX1_HUMAN
NC score	0.052600 (rank : 919)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

NTRK2_HUMAN
NC score	0.052478 (rank : 920)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	453	Target Neighborhood Hits	1081	Shared Neighborhood Hits	104
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

ZNFX1_MOUSE
NC score	0.052444 (rank : 921)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	453	Target Neighborhood Hits	407	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

MT1L_HUMAN
NC score	0.052409 (rank : 922)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	38
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

CO1A1_MOUSE
NC score	0.052310 (rank : 923)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	40
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_MOUSE
NC score	0.052298 (rank : 924)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	453	Target Neighborhood Hits	466	Shared Neighborhood Hits	32
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

NTRK2_MOUSE
NC score	0.052030 (rank : 925)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	453	Target Neighborhood Hits	1088	Shared Neighborhood Hits	104
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

KR122_HUMAN
NC score	0.051885 (rank : 926)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	453	Target Neighborhood Hits	97	Shared Neighborhood Hits	54
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

NTRK3_HUMAN
NC score	0.051736 (rank : 927)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	453	Target Neighborhood Hits	1115	Shared Neighborhood Hits	104
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

IGS21_HUMAN
NC score	0.051395 (rank : 928)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	453	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

PSG3_HUMAN
NC score	0.051309 (rank : 929)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	453	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

ESAM_HUMAN
NC score	0.051296 (rank : 930)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	453	Target Neighborhood Hits	251	Shared Neighborhood Hits	48
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

BMP1_MOUSE
NC score	0.051257 (rank : 931)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CEAM8_HUMAN
NC score	0.051217 (rank : 932)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

TLL1_MOUSE
NC score	0.051056 (rank : 933)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	453	Target Neighborhood Hits	237	Shared Neighborhood Hits	90
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

ITAX_MOUSE
NC score	0.050821 (rank : 934)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	453	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXH4	Gene names	Itgax
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD11c antigen).

CXAR_HUMAN
NC score	0.050679 (rank : 935)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	46
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

BMP1_HUMAN
NC score	0.050618 (rank : 936)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	89
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

UNC5A_MOUSE
NC score	0.050538 (rank : 937)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	453	Target Neighborhood Hits	203	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

IGS21_MOUSE
NC score	0.050465 (rank : 938)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	453	Target Neighborhood Hits	118	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

LEPR_MOUSE
NC score	0.050329 (rank : 939)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	453	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

PSG4_HUMAN
NC score	0.050296 (rank : 940)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	453	Target Neighborhood Hits	243	Shared Neighborhood Hits	53
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

CO5A1_HUMAN
NC score	0.050195 (rank : 941)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	453	Target Neighborhood Hits	434	Shared Neighborhood Hits	23
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

IRPL1_HUMAN
NC score	0.050068 (rank : 942)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

ADEC1_HUMAN
NC score	0.050028 (rank : 943)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	453	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ATS9_HUMAN
NC score	0.046940 (rank : 944)	θ value	0.813845 (rank : 331)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	82
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

TRIM9_HUMAN
NC score	0.041621 (rank : 945)	θ value	0.813845 (rank : 346)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	42
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

FLRT3_HUMAN
NC score	0.041423 (rank : 946)	θ value	0.813845 (rank : 335)
Query Neighborhood Hits	453	Target Neighborhood Hits	281	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZU0, Q96K39, Q96K42, Q96KB1, Q9P259	Gene names	FLRT3, KIAA1469
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT3 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 3).

K0319_MOUSE
NC score	0.040910 (rank : 947)	θ value	5.27518 (rank : 422)
Query Neighborhood Hits	453	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

CFAI_MOUSE
NC score	0.037353 (rank : 948)	θ value	1.38821 (rank : 360)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	63
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TRIM9_MOUSE
NC score	0.036424 (rank : 949)	θ value	0.813845 (rank : 347)
Query Neighborhood Hits	453	Target Neighborhood Hits	274	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

CFAI_HUMAN
NC score	0.036274 (rank : 950)	θ value	1.38821 (rank : 359)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	58
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

ENPP2_MOUSE
NC score	0.035323 (rank : 951)	θ value	3.0926 (rank : 392)
Query Neighborhood Hits	453	Target Neighborhood Hits	66	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ERBB4_HUMAN
NC score	0.034535 (rank : 952)	θ value	0.365318 (rank : 314)
Query Neighborhood Hits	453	Target Neighborhood Hits	910	Shared Neighborhood Hits	93
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

HTRA3_MOUSE
NC score	0.032888 (rank : 953)	θ value	0.21417 (rank : 292)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

BAI1_MOUSE
NC score	0.027050 (rank : 954)	θ value	0.125558 (rank : 268)
Query Neighborhood Hits	453	Target Neighborhood Hits	340	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

VEGFD_MOUSE
NC score	0.026198 (rank : 955)	θ value	0.62314 (rank : 329)
Query Neighborhood Hits	453	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P97946	Gene names	Figf, Vegfd
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

K0319_HUMAN
NC score	0.025442 (rank : 956)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	453	Target Neighborhood Hits	154	Shared Neighborhood Hits	24
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

HTRA3_HUMAN
NC score	0.024311 (rank : 957)	θ value	0.813845 (rank : 336)
Query Neighborhood Hits	453	Target Neighborhood Hits	152	Shared Neighborhood Hits	24
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

BAI2_MOUSE
NC score	0.022991 (rank : 958)	θ value	3.0926 (rank : 387)
Query Neighborhood Hits	453	Target Neighborhood Hits	323	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
NC score	0.022537 (rank : 959)	θ value	4.03905 (rank : 405)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	35
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

SEPP1_MOUSE
NC score	0.016956 (rank : 960)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	453	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P70274, Q9Z2T7	Gene names	Sepp1, Selp
Domain Architecture
Description	Selenoprotein P precursor (SeP) (Plasma selenoprotein P).

CAD16_HUMAN
NC score	0.012276 (rank : 961)	θ value	6.88961 (rank : 430)
Query Neighborhood Hits	453	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

EGLN_MOUSE
NC score	0.011117 (rank : 962)	θ value	1.81305 (rank : 369)
Query Neighborhood Hits	453	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q63961, Q61520	Gene names	Eng, Edg
Domain Architecture
Description	Endoglin precursor (Cell surface MJ7/18 antigen).

I13R1_HUMAN
NC score	0.010479 (rank : 963)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

IL2RB_MOUSE
NC score	0.010261 (rank : 964)	θ value	5.27518 (rank : 421)
Query Neighborhood Hits	453	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

SHAN2_HUMAN
NC score	0.007367 (rank : 965)	θ value	5.27518 (rank : 425)
Query Neighborhood Hits	453	Target Neighborhood Hits	346	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

FREM2_MOUSE
NC score	0.006588 (rank : 966)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

SYNP2_HUMAN
NC score	0.000603 (rank : 967)	θ value	8.99809 (rank : 452)
Query Neighborhood Hits	453	Target Neighborhood Hits	323	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

WNK2_HUMAN
NC score	0.000397 (rank : 968)	θ value	2.36792 (rank : 386)
Query Neighborhood Hits	453	Target Neighborhood Hits	1407	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ATP9B_HUMAN
NC score	0.000133 (rank : 969)	θ value	6.88961 (rank : 429)
Query Neighborhood Hits	453	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	O43861, O60872	Gene names	ATP9B, ATPIIB, NEO1L
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1).

ATP9B_MOUSE
NC score	0.000007 (rank : 970)	θ value	8.99809 (rank : 438)
Query Neighborhood Hits	453	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P98195, Q99LI3	Gene names	Atp9b
Domain Architecture
Description	Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1).

PLAP_HUMAN
NC score	-0.000068 (rank : 971)	θ value	2.36792 (rank : 384)
Query Neighborhood Hits	453	Target Neighborhood Hits	266	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

PLAP_MOUSE
NC score	-0.001231 (rank : 972)	θ value	6.88961 (rank : 435)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

ZBT16_HUMAN
NC score	-0.011991 (rank : 973)	θ value	4.03905 (rank : 418)
Query Neighborhood Hits	453	Target Neighborhood Hits	1010	Shared Neighborhood Hits	11
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).