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Network neighborhood for query Sequence : TEFF2_HUMAN

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TEFF2_HUMAN
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TEFF2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	211	Target Neighborhood Hits	211	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	0 (rank : 2)	NC score	0.998647 (rank : 2)
Query Neighborhood Hits	211	Target Neighborhood Hits	214	Shared Neighborhood Hits	209
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

AGRIN_HUMAN
θ value	4.43474e-23 (rank : 3)	NC score	0.472503 (rank : 14)
Query Neighborhood Hits	211	Target Neighborhood Hits	582	Shared Neighborhood Hits	182
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FST_MOUSE
θ value	3.52202e-12 (rank : 4)	NC score	0.527571 (rank : 4)
Query Neighborhood Hits	211	Target Neighborhood Hits	146	Shared Neighborhood Hits	93
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_HUMAN
θ value	7.84624e-12 (rank : 5)	NC score	0.524410 (rank : 5)
Query Neighborhood Hits	211	Target Neighborhood Hits	129	Shared Neighborhood Hits	88
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

BTC_MOUSE
θ value	1.9326e-10 (rank : 6)	NC score	0.551945 (rank : 3)
Query Neighborhood Hits	211	Target Neighborhood Hits	67	Shared Neighborhood Hits	60
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

EGF_MOUSE
θ value	9.59137e-10 (rank : 7)	NC score	0.321458 (rank : 46)
Query Neighborhood Hits	211	Target Neighborhood Hits	358	Shared Neighborhood Hits	134
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

BTC_HUMAN
θ value	2.79066e-09 (rank : 8)	NC score	0.519778 (rank : 6)
Query Neighborhood Hits	211	Target Neighborhood Hits	70	Shared Neighborhood Hits	55
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

TGFA_HUMAN
θ value	1.80886e-08 (rank : 9)	NC score	0.508741 (rank : 7)
Query Neighborhood Hits	211	Target Neighborhood Hits	61	Shared Neighborhood Hits	56
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TGFA_MOUSE
θ value	3.08544e-08 (rank : 10)	NC score	0.500924 (rank : 8)
Query Neighborhood Hits	211	Target Neighborhood Hits	62	Shared Neighborhood Hits	53
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

FSTL5_HUMAN
θ value	6.87365e-08 (rank : 11)	NC score	0.243029 (rank : 121)
Query Neighborhood Hits	211	Target Neighborhood Hits	347	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	1.53129e-07 (rank : 12)	NC score	0.240401 (rank : 125)
Query Neighborhood Hits	211	Target Neighborhood Hits	355	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

EREG_MOUSE
θ value	1.99992e-07 (rank : 13)	NC score	0.485389 (rank : 12)
Query Neighborhood Hits	211	Target Neighborhood Hits	65	Shared Neighborhood Hits	55
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

FSTL3_MOUSE
θ value	2.61198e-07 (rank : 14)	NC score	0.482588 (rank : 13)
Query Neighborhood Hits	211	Target Neighborhood Hits	152	Shared Neighborhood Hits	94
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

EPGN_MOUSE
θ value	3.41135e-07 (rank : 15)	NC score	0.491926 (rank : 10)
Query Neighborhood Hits	211	Target Neighborhood Hits	63	Shared Neighborhood Hits	57
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

NOTC1_HUMAN
θ value	3.41135e-07 (rank : 16)	NC score	0.328163 (rank : 38)
Query Neighborhood Hits	211	Target Neighborhood Hits	906	Shared Neighborhood Hits	151
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SMOC1_HUMAN
θ value	3.41135e-07 (rank : 17)	NC score	0.323678 (rank : 43)
Query Neighborhood Hits	211	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

EREG_HUMAN
θ value	4.45536e-07 (rank : 18)	NC score	0.497252 (rank : 9)
Query Neighborhood Hits	211	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EGF_HUMAN
θ value	5.81887e-07 (rank : 19)	NC score	0.303907 (rank : 56)
Query Neighborhood Hits	211	Target Neighborhood Hits	343	Shared Neighborhood Hits	129
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

FSTL3_HUMAN
θ value	5.81887e-07 (rank : 20)	NC score	0.487805 (rank : 11)
Query Neighborhood Hits	211	Target Neighborhood Hits	162	Shared Neighborhood Hits	101
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

NOTC2_HUMAN
θ value	1.69304e-06 (rank : 21)	NC score	0.325707 (rank : 40)
Query Neighborhood Hits	211	Target Neighborhood Hits	1113	Shared Neighborhood Hits	156
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

AREG_HUMAN
θ value	2.21117e-06 (rank : 22)	NC score	0.422359 (rank : 18)
Query Neighborhood Hits	211	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	P15514	Gene names	AREG
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Colorectum cell-derived growth factor) (CRDGF).

FSTL4_MOUSE
θ value	2.88788e-06 (rank : 23)	NC score	0.245801 (rank : 120)
Query Neighborhood Hits	211	Target Neighborhood Hits	333	Shared Neighborhood Hits	53
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL4_HUMAN
θ value	3.77169e-06 (rank : 24)	NC score	0.239998 (rank : 127)
Query Neighborhood Hits	211	Target Neighborhood Hits	344	Shared Neighborhood Hits	52
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

SMOC1_MOUSE
θ value	3.77169e-06 (rank : 25)	NC score	0.323056 (rank : 45)
Query Neighborhood Hits	211	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

HBEGF_HUMAN
θ value	6.43352e-06 (rank : 26)	NC score	0.441499 (rank : 16)
Query Neighborhood Hits	211	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

NOTC2_MOUSE
θ value	8.40245e-06 (rank : 27)	NC score	0.326070 (rank : 39)
Query Neighborhood Hits	211	Target Neighborhood Hits	1069	Shared Neighborhood Hits	158
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

JAG1_MOUSE
θ value	1.09739e-05 (rank : 28)	NC score	0.350277 (rank : 24)
Query Neighborhood Hits	211	Target Neighborhood Hits	518	Shared Neighborhood Hits	145
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FSTL1_HUMAN
θ value	1.43324e-05 (rank : 29)	NC score	0.418745 (rank : 19)
Query Neighborhood Hits	211	Target Neighborhood Hits	68	Shared Neighborhood Hits	50
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	1.43324e-05 (rank : 30)	NC score	0.417095 (rank : 20)
Query Neighborhood Hits	211	Target Neighborhood Hits	74	Shared Neighborhood Hits	50
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

HBEGF_MOUSE
θ value	1.43324e-05 (rank : 31)	NC score	0.424654 (rank : 17)
Query Neighborhood Hits	211	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

NOTC3_HUMAN
θ value	1.43324e-05 (rank : 32)	NC score	0.323598 (rank : 44)
Query Neighborhood Hits	211	Target Neighborhood Hits	1062	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

AREG_MOUSE
θ value	1.87187e-05 (rank : 33)	NC score	0.407038 (rank : 21)
Query Neighborhood Hits	211	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	P31955	Gene names	Areg, Sdgf
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Schwannoma-derived growth factor) (SDGF).

SMOC2_MOUSE
θ value	5.44631e-05 (rank : 34)	NC score	0.297494 (rank : 62)
Query Neighborhood Hits	211	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

JAG1_HUMAN
θ value	7.1131e-05 (rank : 35)	NC score	0.347734 (rank : 27)
Query Neighborhood Hits	211	Target Neighborhood Hits	514	Shared Neighborhood Hits	143
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

NOTC1_MOUSE
θ value	7.1131e-05 (rank : 36)	NC score	0.333451 (rank : 34)
Query Neighborhood Hits	211	Target Neighborhood Hits	916	Shared Neighborhood Hits	154
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SMOC2_HUMAN
θ value	7.1131e-05 (rank : 37)	NC score	0.295073 (rank : 66)
Query Neighborhood Hits	211	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

EPGN_HUMAN
θ value	0.000121331 (rank : 38)	NC score	0.453334 (rank : 15)
Query Neighborhood Hits	211	Target Neighborhood Hits	59	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

NOTC3_MOUSE
θ value	0.000121331 (rank : 39)	NC score	0.320260 (rank : 47)
Query Neighborhood Hits	211	Target Neighborhood Hits	975	Shared Neighborhood Hits	152
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ISK5_HUMAN
θ value	0.00020696 (rank : 40)	NC score	0.300037 (rank : 58)
Query Neighborhood Hits	211	Target Neighborhood Hits	89	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

MEGF6_HUMAN
θ value	0.00102713 (rank : 41)	NC score	0.301751 (rank : 57)
Query Neighborhood Hits	211	Target Neighborhood Hits	671	Shared Neighborhood Hits	152
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

SLIT2_MOUSE
θ value	0.00102713 (rank : 42)	NC score	0.262136 (rank : 93)
Query Neighborhood Hits	211	Target Neighborhood Hits	684	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

VEGFC_HUMAN
θ value	0.00102713 (rank : 43)	NC score	0.148274 (rank : 298)
Query Neighborhood Hits	211	Target Neighborhood Hits	128	Shared Neighborhood Hits	59
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CRUM1_HUMAN
θ value	0.00134147 (rank : 44)	NC score	0.339498 (rank : 32)
Query Neighborhood Hits	211	Target Neighborhood Hits	457	Shared Neighborhood Hits	141
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

NOTC4_MOUSE
θ value	0.00134147 (rank : 45)	NC score	0.307698 (rank : 53)
Query Neighborhood Hits	211	Target Neighborhood Hits	872	Shared Neighborhood Hits	155
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

IPK1_HUMAN
θ value	0.00175202 (rank : 46)	NC score	0.349832 (rank : 25)
Query Neighborhood Hits	211	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

ITB5_MOUSE
θ value	0.00175202 (rank : 47)	NC score	0.253950 (rank : 108)
Query Neighborhood Hits	211	Target Neighborhood Hits	329	Shared Neighborhood Hits	125
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

SLIT3_HUMAN
θ value	0.00175202 (rank : 48)	NC score	0.259075 (rank : 99)
Query Neighborhood Hits	211	Target Neighborhood Hits	682	Shared Neighborhood Hits	145
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

NRG2_HUMAN
θ value	0.00228821 (rank : 49)	NC score	0.261372 (rank : 94)
Query Neighborhood Hits	211	Target Neighborhood Hits	419	Shared Neighborhood Hits	87
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	0.00228821 (rank : 50)	NC score	0.279415 (rank : 74)
Query Neighborhood Hits	211	Target Neighborhood Hits	392	Shared Neighborhood Hits	96
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

TENA_HUMAN
θ value	0.00228821 (rank : 51)	NC score	0.266289 (rank : 85)
Query Neighborhood Hits	211	Target Neighborhood Hits	631	Shared Neighborhood Hits	136
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

DNER_MOUSE
θ value	0.00298849 (rank : 52)	NC score	0.349195 (rank : 26)
Query Neighborhood Hits	211	Target Neighborhood Hits	413	Shared Neighborhood Hits	142
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

SLIT2_HUMAN
θ value	0.00298849 (rank : 53)	NC score	0.265182 (rank : 88)
Query Neighborhood Hits	211	Target Neighborhood Hits	708	Shared Neighborhood Hits	150
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NRG4_MOUSE
θ value	0.00390308 (rank : 54)	NC score	0.393777 (rank : 22)
Query Neighborhood Hits	211	Target Neighborhood Hits	79	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

STAB1_MOUSE
θ value	0.00390308 (rank : 55)	NC score	0.295992 (rank : 65)
Query Neighborhood Hits	211	Target Neighborhood Hits	566	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_MOUSE
θ value	0.00390308 (rank : 56)	NC score	0.299184 (rank : 60)
Query Neighborhood Hits	211	Target Neighborhood Hits	528	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SLIT1_HUMAN
θ value	0.00509761 (rank : 57)	NC score	0.264661 (rank : 90)
Query Neighborhood Hits	211	Target Neighborhood Hits	700	Shared Neighborhood Hits	145
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

TENA_MOUSE
θ value	0.00665767 (rank : 58)	NC score	0.267721 (rank : 82)
Query Neighborhood Hits	211	Target Neighborhood Hits	596	Shared Neighborhood Hits	135
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TICN2_MOUSE
θ value	0.00665767 (rank : 59)	NC score	0.232395 (rank : 136)
Query Neighborhood Hits	211	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

JAG2_HUMAN
θ value	0.00869519 (rank : 60)	NC score	0.338398 (rank : 33)
Query Neighborhood Hits	211	Target Neighborhood Hits	491	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NOTC4_HUMAN
θ value	0.00869519 (rank : 61)	NC score	0.304325 (rank : 55)
Query Neighborhood Hits	211	Target Neighborhood Hits	905	Shared Neighborhood Hits	153
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TICN3_HUMAN
θ value	0.00869519 (rank : 62)	NC score	0.225894 (rank : 147)
Query Neighborhood Hits	211	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
θ value	0.00869519 (rank : 63)	NC score	0.231519 (rank : 137)
Query Neighborhood Hits	211	Target Neighborhood Hits	83	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

ISK7_HUMAN
θ value	0.0113563 (rank : 64)	NC score	0.297122 (rank : 64)
Query Neighborhood Hits	211	Target Neighborhood Hits	31	Shared Neighborhood Hits	29
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

ITB7_HUMAN
θ value	0.0113563 (rank : 65)	NC score	0.253800 (rank : 109)
Query Neighborhood Hits	211	Target Neighborhood Hits	290	Shared Neighborhood Hits	120
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

SLIT3_MOUSE
θ value	0.0113563 (rank : 66)	NC score	0.259179 (rank : 98)
Query Neighborhood Hits	211	Target Neighborhood Hits	700	Shared Neighborhood Hits	150
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

DLL4_HUMAN
θ value	0.0148317 (rank : 67)	NC score	0.339884 (rank : 31)
Query Neighborhood Hits	211	Target Neighborhood Hits	435	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

IBP7_MOUSE
θ value	0.0148317 (rank : 68)	NC score	0.170780 (rank : 254)
Query Neighborhood Hits	211	Target Neighborhood Hits	230	Shared Neighborhood Hits	38
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

NRG1_HUMAN
θ value	0.0148317 (rank : 69)	NC score	0.288714 (rank : 69)
Query Neighborhood Hits	211	Target Neighborhood Hits	285	Shared Neighborhood Hits	87
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

TICN2_HUMAN
θ value	0.0148317 (rank : 70)	NC score	0.223743 (rank : 151)
Query Neighborhood Hits	211	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

ITB5_HUMAN
θ value	0.0193708 (rank : 71)	NC score	0.249218 (rank : 116)
Query Neighborhood Hits	211	Target Neighborhood Hits	310	Shared Neighborhood Hits	122
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

LAMA3_HUMAN
θ value	0.0193708 (rank : 72)	NC score	0.162647 (rank : 271)
Query Neighborhood Hits	211	Target Neighborhood Hits	760	Shared Neighborhood Hits	118
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LDLR_MOUSE
θ value	0.0193708 (rank : 73)	NC score	0.191635 (rank : 209)
Query Neighborhood Hits	211	Target Neighborhood Hits	382	Shared Neighborhood Hits	107
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

DLL1_MOUSE
θ value	0.0252991 (rank : 74)	NC score	0.332273 (rank : 36)
Query Neighborhood Hits	211	Target Neighborhood Hits	456	Shared Neighborhood Hits	138
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL4_MOUSE
θ value	0.0252991 (rank : 75)	NC score	0.342523 (rank : 29)
Query Neighborhood Hits	211	Target Neighborhood Hits	440	Shared Neighborhood Hits	142
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	0.0252991 (rank : 76)	NC score	0.345728 (rank : 28)
Query Neighborhood Hits	211	Target Neighborhood Hits	460	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

ITB3_HUMAN
θ value	0.0252991 (rank : 77)	NC score	0.248783 (rank : 117)
Query Neighborhood Hits	211	Target Neighborhood Hits	325	Shared Neighborhood Hits	123
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LRP2_HUMAN
θ value	0.0252991 (rank : 78)	NC score	0.201957 (rank : 195)
Query Neighborhood Hits	211	Target Neighborhood Hits	573	Shared Neighborhood Hits	147
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

STAB1_HUMAN
θ value	0.0252991 (rank : 79)	NC score	0.291303 (rank : 67)
Query Neighborhood Hits	211	Target Neighborhood Hits	546	Shared Neighborhood Hits	141
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

CFAI_MOUSE
θ value	0.0330416 (rank : 80)	NC score	0.058042 (rank : 482)
Query Neighborhood Hits	211	Target Neighborhood Hits	290	Shared Neighborhood Hits	52
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

FBN2_HUMAN
θ value	0.0330416 (rank : 81)	NC score	0.279648 (rank : 73)
Query Neighborhood Hits	211	Target Neighborhood Hits	560	Shared Neighborhood Hits	143
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG2_MOUSE
θ value	0.0330416 (rank : 82)	NC score	0.341669 (rank : 30)
Query Neighborhood Hits	211	Target Neighborhood Hits	504	Shared Neighborhood Hits	145
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NRG4_HUMAN
θ value	0.0330416 (rank : 83)	NC score	0.390077 (rank : 23)
Query Neighborhood Hits	211	Target Neighborhood Hits	85	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

SPRC_HUMAN
θ value	0.0330416 (rank : 84)	NC score	0.235408 (rank : 133)
Query Neighborhood Hits	211	Target Neighborhood Hits	45	Shared Neighborhood Hits	39
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

DLL1_HUMAN
θ value	0.0431538 (rank : 85)	NC score	0.332534 (rank : 35)
Query Neighborhood Hits	211	Target Neighborhood Hits	455	Shared Neighborhood Hits	137
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

IBP7_HUMAN
θ value	0.0431538 (rank : 86)	NC score	0.169260 (rank : 257)
Query Neighborhood Hits	211	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

ITB7_MOUSE
θ value	0.0431538 (rank : 87)	NC score	0.249966 (rank : 115)
Query Neighborhood Hits	211	Target Neighborhood Hits	277	Shared Neighborhood Hits	117
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

HABP2_MOUSE
θ value	0.0563607 (rank : 88)	NC score	0.155758 (rank : 284)
Query Neighborhood Hits	211	Target Neighborhood Hits	445	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

SREC2_MOUSE
θ value	0.0563607 (rank : 89)	NC score	0.297913 (rank : 61)
Query Neighborhood Hits	211	Target Neighborhood Hits	605	Shared Neighborhood Hits	131
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TENX_HUMAN
θ value	0.0563607 (rank : 90)	NC score	0.265184 (rank : 87)
Query Neighborhood Hits	211	Target Neighborhood Hits	789	Shared Neighborhood Hits	135
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ZAN_HUMAN
θ value	0.0563607 (rank : 91)	NC score	0.147729 (rank : 301)
Query Neighborhood Hits	211	Target Neighborhood Hits	679	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CUBN_HUMAN
θ value	0.0736092 (rank : 92)	NC score	0.259650 (rank : 96)
Query Neighborhood Hits	211	Target Neighborhood Hits	482	Shared Neighborhood Hits	139
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

ISK4_HUMAN
θ value	0.0736092 (rank : 93)	NC score	0.299385 (rank : 59)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

SO1B2_MOUSE
θ value	0.0736092 (rank : 94)	NC score	0.087447 (rank : 388)
Query Neighborhood Hits	211	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SPRC_MOUSE
θ value	0.0736092 (rank : 95)	NC score	0.232627 (rank : 135)
Query Neighborhood Hits	211	Target Neighborhood Hits	46	Shared Neighborhood Hits	40
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

FBN2_MOUSE
θ value	0.0961366 (rank : 96)	NC score	0.276784 (rank : 76)
Query Neighborhood Hits	211	Target Neighborhood Hits	549	Shared Neighborhood Hits	141
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

NOV_HUMAN
θ value	0.0961366 (rank : 97)	NC score	0.068008 (rank : 450)
Query Neighborhood Hits	211	Target Neighborhood Hits	128	Shared Neighborhood Hits	30
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

SLIT1_MOUSE
θ value	0.0961366 (rank : 98)	NC score	0.260452 (rank : 95)
Query Neighborhood Hits	211	Target Neighborhood Hits	715	Shared Neighborhood Hits	146
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

CRUM1_MOUSE
θ value	0.125558 (rank : 99)	NC score	0.330770 (rank : 37)
Query Neighborhood Hits	211	Target Neighborhood Hits	444	Shared Neighborhood Hits	145
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

ISK4_MOUSE
θ value	0.125558 (rank : 100)	NC score	0.273419 (rank : 78)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

LTBP3_HUMAN
θ value	0.125558 (rank : 101)	NC score	0.266637 (rank : 84)
Query Neighborhood Hits	211	Target Neighborhood Hits	502	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CO6_HUMAN
θ value	0.163984 (rank : 102)	NC score	0.108670 (rank : 356)
Query Neighborhood Hits	211	Target Neighborhood Hits	331	Shared Neighborhood Hits	86
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ITB3_MOUSE
θ value	0.163984 (rank : 103)	NC score	0.241038 (rank : 124)
Query Neighborhood Hits	211	Target Neighborhood Hits	319	Shared Neighborhood Hits	119
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LRP1_HUMAN
θ value	0.163984 (rank : 104)	NC score	0.241774 (rank : 123)
Query Neighborhood Hits	211	Target Neighborhood Hits	617	Shared Neighborhood Hits	151
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

RECK_HUMAN
θ value	0.163984 (rank : 105)	NC score	0.214386 (rank : 172)
Query Neighborhood Hits	211	Target Neighborhood Hits	189	Shared Neighborhood Hits	95
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

ISK6_MOUSE
θ value	0.21417 (rank : 106)	NC score	0.282865 (rank : 71)
Query Neighborhood Hits	211	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

NELL2_HUMAN
θ value	0.21417 (rank : 107)	NC score	0.267382 (rank : 83)
Query Neighborhood Hits	211	Target Neighborhood Hits	449	Shared Neighborhood Hits	130
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

RELN_HUMAN
θ value	0.21417 (rank : 108)	NC score	0.157952 (rank : 277)
Query Neighborhood Hits	211	Target Neighborhood Hits	233	Shared Neighborhood Hits	99
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

SO1A4_MOUSE
θ value	0.21417 (rank : 109)	NC score	0.081692 (rank : 405)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

HTRA1_MOUSE
θ value	0.279714 (rank : 110)	NC score	0.112763 (rank : 347)
Query Neighborhood Hits	211	Target Neighborhood Hits	140	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

ISK3_MOUSE
θ value	0.279714 (rank : 111)	NC score	0.253028 (rank : 111)
Query Neighborhood Hits	211	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

ITB2_MOUSE
θ value	0.279714 (rank : 112)	NC score	0.240235 (rank : 126)
Query Neighborhood Hits	211	Target Neighborhood Hits	326	Shared Neighborhood Hits	122
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KAZD1_HUMAN
θ value	0.279714 (rank : 113)	NC score	0.172017 (rank : 252)
Query Neighborhood Hits	211	Target Neighborhood Hits	248	Shared Neighborhood Hits	47
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KRA59_HUMAN
θ value	0.279714 (rank : 114)	NC score	0.278584 (rank : 75)
Query Neighborhood Hits	211	Target Neighborhood Hits	310	Shared Neighborhood Hits	96
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LTB1L_MOUSE
θ value	0.279714 (rank : 115)	NC score	0.259316 (rank : 97)
Query Neighborhood Hits	211	Target Neighborhood Hits	514	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.279714 (rank : 116)	NC score	0.258827 (rank : 100)
Query Neighborhood Hits	211	Target Neighborhood Hits	479	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MEGF9_MOUSE
θ value	0.279714 (rank : 117)	NC score	0.211036 (rank : 180)
Query Neighborhood Hits	211	Target Neighborhood Hits	896	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

RELN_MOUSE
θ value	0.279714 (rank : 118)	NC score	0.162318 (rank : 272)
Query Neighborhood Hits	211	Target Neighborhood Hits	235	Shared Neighborhood Hits	102
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

CSPG3_MOUSE
θ value	0.365318 (rank : 119)	NC score	0.202118 (rank : 194)
Query Neighborhood Hits	211	Target Neighborhood Hits	657	Shared Neighborhood Hits	120
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

HABP2_HUMAN
θ value	0.365318 (rank : 120)	NC score	0.151980 (rank : 288)
Query Neighborhood Hits	211	Target Neighborhood Hits	431	Shared Neighborhood Hits	115
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

KAZD1_MOUSE
θ value	0.365318 (rank : 121)	NC score	0.160689 (rank : 273)
Query Neighborhood Hits	211	Target Neighborhood Hits	281	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

NRG3_MOUSE
θ value	0.365318 (rank : 122)	NC score	0.187001 (rank : 219)
Query Neighborhood Hits	211	Target Neighborhood Hits	132	Shared Neighborhood Hits	65
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

STAB2_HUMAN
θ value	0.365318 (rank : 123)	NC score	0.290962 (rank : 68)
Query Neighborhood Hits	211	Target Neighborhood Hits	534	Shared Neighborhood Hits	140
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ISK6_HUMAN
θ value	0.47712 (rank : 124)	NC score	0.269376 (rank : 80)
Query Neighborhood Hits	211	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

NELL1_HUMAN
θ value	0.47712 (rank : 125)	NC score	0.267757 (rank : 81)
Query Neighborhood Hits	211	Target Neighborhood Hits	451	Shared Neighborhood Hits	134
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

WIF1_MOUSE
θ value	0.47712 (rank : 126)	NC score	0.306967 (rank : 54)
Query Neighborhood Hits	211	Target Neighborhood Hits	393	Shared Neighborhood Hits	127
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KRA55_HUMAN
θ value	0.62314 (rank : 127)	NC score	0.257570 (rank : 103)
Query Neighborhood Hits	211	Target Neighborhood Hits	257	Shared Neighborhood Hits	96
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LAMB2_HUMAN
θ value	0.62314 (rank : 128)	NC score	0.207503 (rank : 185)
Query Neighborhood Hits	211	Target Neighborhood Hits	692	Shared Neighborhood Hits	124
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMC2_MOUSE
θ value	0.62314 (rank : 129)	NC score	0.193919 (rank : 208)
Query Neighborhood Hits	211	Target Neighborhood Hits	614	Shared Neighborhood Hits	119
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LTB1S_HUMAN
θ value	0.62314 (rank : 130)	NC score	0.256505 (rank : 104)
Query Neighborhood Hits	211	Target Neighborhood Hits	502	Shared Neighborhood Hits	131
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SO1A5_MOUSE
θ value	0.62314 (rank : 131)	NC score	0.079027 (rank : 415)
Query Neighborhood Hits	211	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

TICN1_HUMAN
θ value	0.62314 (rank : 132)	NC score	0.181627 (rank : 231)
Query Neighborhood Hits	211	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

CUBN_MOUSE
θ value	0.813845 (rank : 133)	NC score	0.251964 (rank : 113)
Query Neighborhood Hits	211	Target Neighborhood Hits	477	Shared Neighborhood Hits	135
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

HTRA1_HUMAN
θ value	0.813845 (rank : 134)	NC score	0.104200 (rank : 361)
Query Neighborhood Hits	211	Target Neighborhood Hits	155	Shared Neighborhood Hits	45
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

CELR3_HUMAN
θ value	1.06291 (rank : 135)	NC score	0.139265 (rank : 312)
Query Neighborhood Hits	211	Target Neighborhood Hits	680	Shared Neighborhood Hits	124
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	1.06291 (rank : 136)	NC score	0.136323 (rank : 321)
Query Neighborhood Hits	211	Target Neighborhood Hits	687	Shared Neighborhood Hits	125
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

NRG3_HUMAN
θ value	1.06291 (rank : 137)	NC score	0.176571 (rank : 239)
Query Neighborhood Hits	211	Target Neighborhood Hits	119	Shared Neighborhood Hits	63
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

SO1B3_HUMAN
θ value	1.06291 (rank : 138)	NC score	0.084883 (rank : 394)
Query Neighborhood Hits	211	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SREC_HUMAN
θ value	1.06291 (rank : 139)	NC score	0.288136 (rank : 70)
Query Neighborhood Hits	211	Target Neighborhood Hits	645	Shared Neighborhood Hits	138
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

DSC1_HUMAN
θ value	1.38821 (rank : 140)	NC score	0.011953 (rank : 510)
Query Neighborhood Hits	211	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q08554	Gene names	DSC1
Domain Architecture
Description	Desmocollin-1 precursor (Desmosomal glycoprotein 2/3) (DG2/DG3).

IPK2_HUMAN
θ value	1.38821 (rank : 141)	NC score	0.227964 (rank : 143)
Query Neighborhood Hits	211	Target Neighborhood Hits	30	Shared Neighborhood Hits	28
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

EGFL9_HUMAN
θ value	1.81305 (rank : 142)	NC score	0.325042 (rank : 41)
Query Neighborhood Hits	211	Target Neighborhood Hits	365	Shared Neighborhood Hits	130
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	1.81305 (rank : 143)	NC score	0.323783 (rank : 42)
Query Neighborhood Hits	211	Target Neighborhood Hits	379	Shared Neighborhood Hits	128
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

FATH_HUMAN
θ value	1.81305 (rank : 144)	NC score	0.165955 (rank : 264)
Query Neighborhood Hits	211	Target Neighborhood Hits	570	Shared Neighborhood Hits	136
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

LYAM2_HUMAN
θ value	1.81305 (rank : 145)	NC score	0.144011 (rank : 307)
Query Neighborhood Hits	211	Target Neighborhood Hits	394	Shared Neighborhood Hits	124
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NAGPA_HUMAN
θ value	1.81305 (rank : 146)	NC score	0.271186 (rank : 79)
Query Neighborhood Hits	211	Target Neighborhood Hits	282	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

PCSK5_MOUSE
θ value	1.81305 (rank : 147)	NC score	0.162944 (rank : 270)
Query Neighborhood Hits	211	Target Neighborhood Hits	613	Shared Neighborhood Hits	116
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

SO1A2_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.084160 (rank : 395)
Query Neighborhood Hits	211	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

TENR_HUMAN
θ value	1.81305 (rank : 149)	NC score	0.186906 (rank : 220)
Query Neighborhood Hits	211	Target Neighborhood Hits	526	Shared Neighborhood Hits	126
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

EDAD_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.042460 (rank : 508)
Query Neighborhood Hits	211	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWZ3, Q5VYJ7	Gene names	EDARADD
Domain Architecture	No domain graphic available
Description	Ectodysplasin A receptor-associated adapter protein (EDAR-associated death domain protein) (Crinkled homolog).

EMR1_MOUSE
θ value	2.36792 (rank : 151)	NC score	0.185639 (rank : 226)
Query Neighborhood Hits	211	Target Neighborhood Hits	349	Shared Neighborhood Hits	98
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

FRAS1_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.151951 (rank : 289)
Query Neighborhood Hits	211	Target Neighborhood Hits	759	Shared Neighborhood Hits	118
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ITB8_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.211238 (rank : 178)
Query Neighborhood Hits	211	Target Neighborhood Hits	280	Shared Neighborhood Hits	110
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

SO1A6_MOUSE
θ value	2.36792 (rank : 154)	NC score	0.075392 (rank : 425)
Query Neighborhood Hits	211	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

DLL3_HUMAN
θ value	3.0926 (rank : 155)	NC score	0.316905 (rank : 49)
Query Neighborhood Hits	211	Target Neighborhood Hits	419	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	3.0926 (rank : 156)	NC score	0.318333 (rank : 48)
Query Neighborhood Hits	211	Target Neighborhood Hits	399	Shared Neighborhood Hits	135
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

FBLN5_HUMAN
θ value	3.0926 (rank : 157)	NC score	0.213606 (rank : 174)
Query Neighborhood Hits	211	Target Neighborhood Hits	329	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBN3_HUMAN
θ value	3.0926 (rank : 158)	NC score	0.274402 (rank : 77)
Query Neighborhood Hits	211	Target Neighborhood Hits	543	Shared Neighborhood Hits	139
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

IPK2_MOUSE
θ value	3.0926 (rank : 159)	NC score	0.175738 (rank : 241)
Query Neighborhood Hits	211	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

ISK7_MOUSE
θ value	3.0926 (rank : 160)	NC score	0.199226 (rank : 200)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

LRP1B_HUMAN
θ value	3.0926 (rank : 161)	NC score	0.242710 (rank : 122)
Query Neighborhood Hits	211	Target Neighborhood Hits	602	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LTBP3_MOUSE
θ value	3.0926 (rank : 162)	NC score	0.256491 (rank : 105)
Query Neighborhood Hits	211	Target Neighborhood Hits	475	Shared Neighborhood Hits	127
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MEP1B_MOUSE
θ value	3.0926 (rank : 163)	NC score	0.069579 (rank : 446)
Query Neighborhood Hits	211	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

SO3A1_HUMAN
θ value	3.0926 (rank : 164)	NC score	0.077065 (rank : 423)
Query Neighborhood Hits	211	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO3A1_MOUSE
θ value	3.0926 (rank : 165)	NC score	0.077256 (rank : 422)
Query Neighborhood Hits	211	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

TENR_MOUSE
θ value	3.0926 (rank : 166)	NC score	0.187322 (rank : 216)
Query Neighborhood Hits	211	Target Neighborhood Hits	531	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

ADAM7_MOUSE
θ value	4.03905 (rank : 167)	NC score	0.034623 (rank : 509)
Query Neighborhood Hits	211	Target Neighborhood Hits	200	Shared Neighborhood Hits	62
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

CSPG3_HUMAN
θ value	4.03905 (rank : 168)	NC score	0.194033 (rank : 207)
Query Neighborhood Hits	211	Target Neighborhood Hits	676	Shared Neighborhood Hits	115
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

HGFA_MOUSE
θ value	4.03905 (rank : 169)	NC score	0.112690 (rank : 348)
Query Neighborhood Hits	211	Target Neighborhood Hits	419	Shared Neighborhood Hits	106
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LAMA2_HUMAN
θ value	4.03905 (rank : 170)	NC score	0.179390 (rank : 233)
Query Neighborhood Hits	211	Target Neighborhood Hits	1092	Shared Neighborhood Hits	129
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_MOUSE
θ value	4.03905 (rank : 171)	NC score	0.169943 (rank : 256)
Query Neighborhood Hits	211	Target Neighborhood Hits	859	Shared Neighborhood Hits	133
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

SMDF_HUMAN
θ value	4.03905 (rank : 172)	NC score	0.220405 (rank : 161)
Query Neighborhood Hits	211	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SO1A1_MOUSE
θ value	4.03905 (rank : 173)	NC score	0.074240 (rank : 427)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO1B1_HUMAN
θ value	4.03905 (rank : 174)	NC score	0.081457 (rank : 406)
Query Neighborhood Hits	211	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO1C1_HUMAN
θ value	4.03905 (rank : 175)	NC score	0.072241 (rank : 433)
Query Neighborhood Hits	211	Target Neighborhood Hits	32	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SO1C1_MOUSE
θ value	4.03905 (rank : 176)	NC score	0.074640 (rank : 426)
Query Neighborhood Hits	211	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO4A1_HUMAN
θ value	4.03905 (rank : 177)	NC score	0.078030 (rank : 419)
Query Neighborhood Hits	211	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

TICN1_MOUSE
θ value	4.03905 (rank : 178)	NC score	0.177725 (rank : 236)
Query Neighborhood Hits	211	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

ADAM8_HUMAN
θ value	5.27518 (rank : 179)	NC score	0.068112 (rank : 449)
Query Neighborhood Hits	211	Target Neighborhood Hits	327	Shared Neighborhood Hits	91
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM9_MOUSE
θ value	5.27518 (rank : 180)	NC score	0.061544 (rank : 470)
Query Neighborhood Hits	211	Target Neighborhood Hits	325	Shared Neighborhood Hits	93
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

CNTP1_HUMAN
θ value	5.27518 (rank : 181)	NC score	0.082723 (rank : 400)
Query Neighborhood Hits	211	Target Neighborhood Hits	196	Shared Neighborhood Hits	64
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

FA10_HUMAN
θ value	5.27518 (rank : 182)	NC score	0.100074 (rank : 368)
Query Neighborhood Hits	211	Target Neighborhood Hits	431	Shared Neighborhood Hits	104
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

HHIP_HUMAN
θ value	5.27518 (rank : 183)	NC score	0.219635 (rank : 164)
Query Neighborhood Hits	211	Target Neighborhood Hits	249	Shared Neighborhood Hits	108
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	5.27518 (rank : 184)	NC score	0.214470 (rank : 171)
Query Neighborhood Hits	211	Target Neighborhood Hits	219	Shared Neighborhood Hits	105
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB1_HUMAN
θ value	5.27518 (rank : 185)	NC score	0.222235 (rank : 156)
Query Neighborhood Hits	211	Target Neighborhood Hits	298	Shared Neighborhood Hits	113
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

LTB1L_HUMAN
θ value	5.27518 (rank : 186)	NC score	0.253153 (rank : 110)
Query Neighborhood Hits	211	Target Neighborhood Hits	553	Shared Neighborhood Hits	130
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SO5A1_HUMAN
θ value	5.27518 (rank : 187)	NC score	0.077957 (rank : 420)
Query Neighborhood Hits	211	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

TIE1_MOUSE
θ value	5.27518 (rank : 188)	NC score	0.082260 (rank : 403)
Query Neighborhood Hits	211	Target Neighborhood Hits	1266	Shared Neighborhood Hits	125
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TPA_MOUSE
θ value	5.27518 (rank : 189)	NC score	0.071180 (rank : 442)
Query Neighborhood Hits	211	Target Neighborhood Hits	335	Shared Neighborhood Hits	90
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ZN208_HUMAN
θ value	5.27518 (rank : 190)	NC score	-0.006120 (rank : 511)
Query Neighborhood Hits	211	Target Neighborhood Hits	771	Shared Neighborhood Hits	8
SwissProt Accessions	O43345	Gene names	ZNF208, ZNF91L
Domain Architecture
Description	Zinc finger protein 208.

CORIN_HUMAN
θ value	6.88961 (rank : 191)	NC score	0.071725 (rank : 437)
Query Neighborhood Hits	211	Target Neighborhood Hits	453	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

KR511_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.202757 (rank : 193)
Query Neighborhood Hits	211	Target Neighborhood Hits	231	Shared Neighborhood Hits	79
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

LRP10_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.050524 (rank : 506)
Query Neighborhood Hits	211	Target Neighborhood Hits	197	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LTBP2_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.258111 (rank : 101)
Query Neighborhood Hits	211	Target Neighborhood Hits	552	Shared Neighborhood Hits	129
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LYAM1_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.126900 (rank : 333)
Query Neighborhood Hits	211	Target Neighborhood Hits	315	Shared Neighborhood Hits	109
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

NAGPA_MOUSE
θ value	6.88961 (rank : 196)	NC score	0.251020 (rank : 114)
Query Neighborhood Hits	211	Target Neighborhood Hits	308	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

PGBM_MOUSE
θ value	6.88961 (rank : 197)	NC score	0.173300 (rank : 249)
Query Neighborhood Hits	211	Target Neighborhood Hits	1073	Shared Neighborhood Hits	149
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

RECK_MOUSE
θ value	6.88961 (rank : 198)	NC score	0.169248 (rank : 258)
Query Neighborhood Hits	211	Target Neighborhood Hits	158	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

EDIL3_MOUSE
θ value	8.99809 (rank : 199)	NC score	0.246661 (rank : 119)
Query Neighborhood Hits	211	Target Neighborhood Hits	317	Shared Neighborhood Hits	116
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FBLN5_MOUSE
θ value	8.99809 (rank : 200)	NC score	0.210636 (rank : 181)
Query Neighborhood Hits	211	Target Neighborhood Hits	317	Shared Neighborhood Hits	101
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.265745 (rank : 86)
Query Neighborhood Hits	211	Target Neighborhood Hits	557	Shared Neighborhood Hits	140
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.265170 (rank : 89)
Query Neighborhood Hits	211	Target Neighborhood Hits	563	Shared Neighborhood Hits	142
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

KRA52_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.196291 (rank : 205)
Query Neighborhood Hits	211	Target Neighborhood Hits	236	Shared Neighborhood Hits	80
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LAMB2_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.202896 (rank : 192)
Query Neighborhood Hits	211	Target Neighborhood Hits	722	Shared Neighborhood Hits	129
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC1_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.171726 (rank : 253)
Query Neighborhood Hits	211	Target Neighborhood Hits	922	Shared Neighborhood Hits	126
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.179225 (rank : 234)
Query Neighborhood Hits	211	Target Neighborhood Hits	856	Shared Neighborhood Hits	126
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LRP1B_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.238201 (rank : 130)
Query Neighborhood Hits	211	Target Neighborhood Hits	606	Shared Neighborhood Hits	151
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LYAM2_MOUSE
θ value	8.99809 (rank : 208)	NC score	0.137947 (rank : 317)
Query Neighborhood Hits	211	Target Neighborhood Hits	420	Shared Neighborhood Hits	127
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NOV_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.047019 (rank : 507)
Query Neighborhood Hits	211	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

PGBM_HUMAN
θ value	8.99809 (rank : 210)	NC score	0.174865 (rank : 244)
Query Neighborhood Hits	211	Target Neighborhood Hits	1113	Shared Neighborhood Hits	150
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

WIF1_HUMAN
θ value	8.99809 (rank : 211)	NC score	0.297155 (rank : 63)
Query Neighborhood Hits	211	Target Neighborhood Hits	392	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ADA11_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.061671 (rank : 469)
Query Neighborhood Hits	211	Target Neighborhood Hits	259	Shared Neighborhood Hits	84
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.061050 (rank : 471)
Query Neighborhood Hits	211	Target Neighborhood Hits	263	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA15_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.052935 (rank : 497)
Query Neighborhood Hits	211	Target Neighborhood Hits	324	Shared Neighborhood Hits	95
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA23_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.058251 (rank : 481)
Query Neighborhood Hits	211	Target Neighborhood Hits	235	Shared Neighborhood Hits	87
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.055045 (rank : 491)
Query Neighborhood Hits	211	Target Neighborhood Hits	245	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADAM8_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.072965 (rank : 430)
Query Neighborhood Hits	211	Target Neighborhood Hits	326	Shared Neighborhood Hits	88
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.052477 (rank : 499)
Query Neighborhood Hits	211	Target Neighborhood Hits	243	Shared Neighborhood Hits	81
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

APR3_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.071624 (rank : 439)
Query Neighborhood Hits	211	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.088410 (rank : 385)
Query Neighborhood Hits	211	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASTN_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.050904 (rank : 505)
Query Neighborhood Hits	211	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.052838 (rank : 498)
Query Neighborhood Hits	211	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATRN_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.147308 (rank : 302)
Query Neighborhood Hits	211	Target Neighborhood Hits	525	Shared Neighborhood Hits	119
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.149722 (rank : 294)
Query Neighborhood Hits	211	Target Neighborhood Hits	519	Shared Neighborhood Hits	120
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BMP1_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.056108 (rank : 487)
Query Neighborhood Hits	211	Target Neighborhood Hits	233	Shared Neighborhood Hits	53
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.056609 (rank : 485)
Query Neighborhood Hits	211	Target Neighborhood Hits	236	Shared Neighborhood Hits	54
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMPER_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.062569 (rank : 466)
Query Neighborhood Hits	211	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.065019 (rank : 460)
Query Neighborhood Hits	211	Target Neighborhood Hits	194	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

C1QR1_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.222908 (rank : 154)
Query Neighborhood Hits	211	Target Neighborhood Hits	493	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.224491 (rank : 150)
Query Neighborhood Hits	211	Target Neighborhood Hits	342	Shared Neighborhood Hits	112
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD248_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.150472 (rank : 291)
Query Neighborhood Hits	211	Target Neighborhood Hits	679	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.151138 (rank : 290)
Query Neighborhood Hits	211	Target Neighborhood Hits	578	Shared Neighborhood Hits	86
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.172782 (rank : 251)
Query Neighborhood Hits	211	Target Neighborhood Hits	353	Shared Neighborhood Hits	101
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.148179 (rank : 299)
Query Neighborhood Hits	211	Target Neighborhood Hits	295	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.127180 (rank : 332)
Query Neighborhood Hits	211	Target Neighborhood Hits	613	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.126114 (rank : 335)
Query Neighborhood Hits	211	Target Neighborhood Hits	617	Shared Neighborhood Hits	129
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.131760 (rank : 325)
Query Neighborhood Hits	211	Target Neighborhood Hits	657	Shared Neighborhood Hits	126
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.121848 (rank : 340)
Query Neighborhood Hits	211	Target Neighborhood Hits	584	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CFC1_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.157110 (rank : 279)
Query Neighborhood Hits	211	Target Neighborhood Hits	148	Shared Neighborhood Hits	84
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.149254 (rank : 295)
Query Neighborhood Hits	211	Target Neighborhood Hits	125	Shared Neighborhood Hits	73
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CLC14_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.052355 (rank : 500)
Query Neighborhood Hits	211	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.059774 (rank : 472)
Query Neighborhood Hits	211	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CNTP1_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.072114 (rank : 434)
Query Neighborhood Hits	211	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.094336 (rank : 376)
Query Neighborhood Hits	211	Target Neighborhood Hits	199	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.093848 (rank : 377)
Query Neighborhood Hits	211	Target Neighborhood Hits	194	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.092609 (rank : 379)
Query Neighborhood Hits	211	Target Neighborhood Hits	195	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.093256 (rank : 378)
Query Neighborhood Hits	211	Target Neighborhood Hits	187	Shared Neighborhood Hits	67
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.098466 (rank : 372)
Query Neighborhood Hits	211	Target Neighborhood Hits	193	Shared Neighborhood Hits	72
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO7_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.081385 (rank : 407)
Query Neighborhood Hits	211	Target Neighborhood Hits	278	Shared Neighborhood Hits	75
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8B_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.052070 (rank : 502)
Query Neighborhood Hits	211	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.073045 (rank : 429)
Query Neighborhood Hits	211	Target Neighborhood Hits	224	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.055350 (rank : 489)
Query Neighborhood Hits	211	Target Neighborhood Hits	147	Shared Neighborhood Hits	47
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.062504 (rank : 467)
Query Neighborhood Hits	211	Target Neighborhood Hits	153	Shared Neighborhood Hits	48
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.178551 (rank : 235)
Query Neighborhood Hits	211	Target Neighborhood Hits	258	Shared Neighborhood Hits	96
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.187970 (rank : 212)
Query Neighborhood Hits	211	Target Neighborhood Hits	290	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CORIN_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.062868 (rank : 464)
Query Neighborhood Hits	211	Target Neighborhood Hits	451	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CRAC1_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.063999 (rank : 463)
Query Neighborhood Hits	211	Target Neighborhood Hits	111	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.066536 (rank : 454)
Query Neighborhood Hits	211	Target Neighborhood Hits	112	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CREL1_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.226125 (rank : 146)
Query Neighborhood Hits	211	Target Neighborhood Hits	441	Shared Neighborhood Hits	108
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.223424 (rank : 152)
Query Neighborhood Hits	211	Target Neighborhood Hits	524	Shared Neighborhood Hits	112
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.184774 (rank : 228)
Query Neighborhood Hits	211	Target Neighborhood Hits	362	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM2_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.313209 (rank : 50)
Query Neighborhood Hits	211	Target Neighborhood Hits	453	Shared Neighborhood Hits	138
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSPG2_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.187345 (rank : 215)
Query Neighborhood Hits	211	Target Neighborhood Hits	681	Shared Neighborhood Hits	121
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.187219 (rank : 217)
Query Neighborhood Hits	211	Target Neighborhood Hits	711	Shared Neighborhood Hits	119
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CTGF_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.054660 (rank : 493)
Query Neighborhood Hits	211	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CYR61_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.053368 (rank : 496)
Query Neighborhood Hits	211	Target Neighborhood Hits	159	Shared Neighborhood Hits	45
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.057711 (rank : 483)
Query Neighborhood Hits	211	Target Neighborhood Hits	156	Shared Neighborhood Hits	44
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DLK_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.308739 (rank : 52)
Query Neighborhood Hits	211	Target Neighborhood Hits	401	Shared Neighborhood Hits	130
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.309337 (rank : 51)
Query Neighborhood Hits	211	Target Neighborhood Hits	374	Shared Neighborhood Hits	127
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

EDIL3_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.234502 (rank : 134)
Query Neighborhood Hits	211	Target Neighborhood Hits	292	Shared Neighborhood Hits	108
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.228433 (rank : 141)
Query Neighborhood Hits	211	Target Neighborhood Hits	325	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.226308 (rank : 145)
Query Neighborhood Hits	211	Target Neighborhood Hits	287	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.216054 (rank : 168)
Query Neighborhood Hits	211	Target Neighborhood Hits	270	Shared Neighborhood Hits	96
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.219970 (rank : 162)
Query Neighborhood Hits	211	Target Neighborhood Hits	266	Shared Neighborhood Hits	97
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

ELTD1_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.111271 (rank : 352)
Query Neighborhood Hits	211	Target Neighborhood Hits	269	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.150280 (rank : 293)
Query Neighborhood Hits	211	Target Neighborhood Hits	288	Shared Neighborhood Hits	86
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.195953 (rank : 206)
Query Neighborhood Hits	211	Target Neighborhood Hits	382	Shared Neighborhood Hits	106
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.176744 (rank : 238)
Query Neighborhood Hits	211	Target Neighborhood Hits	345	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.071212 (rank : 441)
Query Neighborhood Hits	211	Target Neighborhood Hits	245	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

ESM1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.083015 (rank : 398)
Query Neighborhood Hits	211	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.076714 (rank : 424)
Query Neighborhood Hits	211	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA10_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.102053 (rank : 366)
Query Neighborhood Hits	211	Target Neighborhood Hits	435	Shared Neighborhood Hits	103
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.099917 (rank : 369)
Query Neighborhood Hits	211	Target Neighborhood Hits	425	Shared Neighborhood Hits	106
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.090684 (rank : 381)
Query Neighborhood Hits	211	Target Neighborhood Hits	404	Shared Neighborhood Hits	95
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.081900 (rank : 404)
Query Neighborhood Hits	211	Target Neighborhood Hits	374	Shared Neighborhood Hits	87
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.098547 (rank : 371)
Query Neighborhood Hits	211	Target Neighborhood Hits	421	Shared Neighborhood Hits	103
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FAT2_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.111025 (rank : 353)
Query Neighborhood Hits	211	Target Neighborhood Hits	507	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FBLN1_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.218733 (rank : 165)
Query Neighborhood Hits	211	Target Neighborhood Hits	324	Shared Neighborhood Hits	106
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.219734 (rank : 163)
Query Neighborhood Hits	211	Target Neighborhood Hits	329	Shared Neighborhood Hits	104
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.228765 (rank : 140)
Query Neighborhood Hits	211	Target Neighborhood Hits	392	Shared Neighborhood Hits	113
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.226759 (rank : 144)
Query Neighborhood Hits	211	Target Neighborhood Hits	505	Shared Neighborhood Hits	112
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.203444 (rank : 189)
Query Neighborhood Hits	211	Target Neighborhood Hits	293	Shared Neighborhood Hits	96
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.203308 (rank : 190)
Query Neighborhood Hits	211	Target Neighborhood Hits	279	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.212980 (rank : 176)
Query Neighborhood Hits	211	Target Neighborhood Hits	278	Shared Neighborhood Hits	97
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.207911 (rank : 184)
Query Neighborhood Hits	211	Target Neighborhood Hits	270	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FRAS1_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.144171 (rank : 306)
Query Neighborhood Hits	211	Target Neighborhood Hits	747	Shared Neighborhood Hits	115
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.218649 (rank : 166)
Query Neighborhood Hits	211	Target Neighborhood Hits	348	Shared Neighborhood Hits	113
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.221768 (rank : 158)
Query Neighborhood Hits	211	Target Neighborhood Hits	343	Shared Neighborhood Hits	113
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GNPTA_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.056340 (rank : 486)
Query Neighborhood Hits	211	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.055133 (rank : 490)
Query Neighborhood Hits	211	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GRN_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.165663 (rank : 265)
Query Neighborhood Hits	211	Target Neighborhood Hits	268	Shared Neighborhood Hits	78
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.173468 (rank : 248)
Query Neighborhood Hits	211	Target Neighborhood Hits	248	Shared Neighborhood Hits	83
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HG2A_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.066089 (rank : 457)
Query Neighborhood Hits	211	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HG2A_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.073172 (rank : 428)
Query Neighborhood Hits	211	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

HGFA_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.109190 (rank : 354)
Query Neighborhood Hits	211	Target Neighborhood Hits	436	Shared Neighborhood Hits	105
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HMCN1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.148872 (rank : 296)
Query Neighborhood Hits	211	Target Neighborhood Hits	983	Shared Neighborhood Hits	117
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HTRA3_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.071099 (rank : 443)
Query Neighborhood Hits	211	Target Neighborhood Hits	152	Shared Neighborhood Hits	41
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.067782 (rank : 451)
Query Neighborhood Hits	211	Target Neighborhood Hits	156	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA4_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.065173 (rank : 459)
Query Neighborhood Hits	211	Target Neighborhood Hits	119	Shared Neighborhood Hits	24
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

IBP1_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.053453 (rank : 495)
Query Neighborhood Hits	211	Target Neighborhood Hits	67	Shared Neighborhood Hits	22
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP1_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.054327 (rank : 494)
Query Neighborhood Hits	211	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP3_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.058322 (rank : 480)
Query Neighborhood Hits	211	Target Neighborhood Hits	67	Shared Neighborhood Hits	20
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

ITB1_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.217873 (rank : 167)
Query Neighborhood Hits	211	Target Neighborhood Hits	283	Shared Neighborhood Hits	112
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.223173 (rank : 153)
Query Neighborhood Hits	211	Target Neighborhood Hits	282	Shared Neighborhood Hits	111
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.200892 (rank : 196)
Query Neighborhood Hits	211	Target Neighborhood Hits	458	Shared Neighborhood Hits	111
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB6_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.224869 (rank : 148)
Query Neighborhood Hits	211	Target Neighborhood Hits	318	Shared Neighborhood Hits	113
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.228339 (rank : 142)
Query Neighborhood Hits	211	Target Neighborhood Hits	341	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.202976 (rank : 191)
Query Neighborhood Hits	211	Target Neighborhood Hits	261	Shared Neighborhood Hits	93
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.199617 (rank : 198)
Query Neighborhood Hits	211	Target Neighborhood Hits	264	Shared Neighborhood Hits	89
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.136647 (rank : 320)
Query Neighborhood Hits	211	Target Neighborhood Hits	212	Shared Neighborhood Hits	76
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR104_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.252885 (rank : 112)
Query Neighborhood Hits	211	Target Neighborhood Hits	313	Shared Neighborhood Hits	107
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.187984 (rank : 211)
Query Neighborhood Hits	211	Target Neighborhood Hits	271	Shared Neighborhood Hits	94
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.237751 (rank : 131)
Query Neighborhood Hits	211	Target Neighborhood Hits	347	Shared Neighborhood Hits	114
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.236559 (rank : 132)
Query Neighborhood Hits	211	Target Neighborhood Hits	330	Shared Neighborhood Hits	111
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.173202 (rank : 250)
Query Neighborhood Hits	211	Target Neighborhood Hits	226	Shared Neighborhood Hits	81
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.188475 (rank : 210)
Query Neighborhood Hits	211	Target Neighborhood Hits	226	Shared Neighborhood Hits	84
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.121114 (rank : 341)
Query Neighborhood Hits	211	Target Neighborhood Hits	232	Shared Neighborhood Hits	74
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.168026 (rank : 261)
Query Neighborhood Hits	211	Target Neighborhood Hits	269	Shared Neighborhood Hits	88
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.174976 (rank : 243)
Query Neighborhood Hits	211	Target Neighborhood Hits	219	Shared Neighborhood Hits	88
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.208144 (rank : 182)
Query Neighborhood Hits	211	Target Neighborhood Hits	144	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.087058 (rank : 390)
Query Neighborhood Hits	211	Target Neighborhood Hits	156	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.130747 (rank : 326)
Query Neighborhood Hits	211	Target Neighborhood Hits	178	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.059012 (rank : 479)
Query Neighborhood Hits	211	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.142880 (rank : 308)
Query Neighborhood Hits	211	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.173502 (rank : 247)
Query Neighborhood Hits	211	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA11_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.148661 (rank : 297)
Query Neighborhood Hits	211	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.159152 (rank : 275)
Query Neighborhood Hits	211	Target Neighborhood Hits	144	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.123439 (rank : 338)
Query Neighborhood Hits	211	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA42_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.090347 (rank : 382)
Query Neighborhood Hits	211	Target Neighborhood Hits	149	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.156135 (rank : 282)
Query Neighborhood Hits	211	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.138677 (rank : 315)
Query Neighborhood Hits	211	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.147764 (rank : 300)
Query Neighborhood Hits	211	Target Neighborhood Hits	204	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.264385 (rank : 91)
Query Neighborhood Hits	211	Target Neighborhood Hits	288	Shared Neighborhood Hits	102
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.263537 (rank : 92)
Query Neighborhood Hits	211	Target Neighborhood Hits	331	Shared Neighborhood Hits	107
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.207203 (rank : 187)
Query Neighborhood Hits	211	Target Neighborhood Hits	270	Shared Neighborhood Hits	89
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA56_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.184690 (rank : 229)
Query Neighborhood Hits	211	Target Neighborhood Hits	207	Shared Neighborhood Hits	79
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.224859 (rank : 149)
Query Neighborhood Hits	211	Target Neighborhood Hits	269	Shared Neighborhood Hits	91
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.246741 (rank : 118)
Query Neighborhood Hits	211	Target Neighborhood Hits	324	Shared Neighborhood Hits	103
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA92_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.136173 (rank : 322)
Query Neighborhood Hits	211	Target Neighborhood Hits	198	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.138473 (rank : 316)
Query Neighborhood Hits	211	Target Neighborhood Hits	203	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.140298 (rank : 310)
Query Neighborhood Hits	211	Target Neighborhood Hits	204	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.132747 (rank : 324)
Query Neighborhood Hits	211	Target Neighborhood Hits	185	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.113021 (rank : 346)
Query Neighborhood Hits	211	Target Neighborhood Hits	173	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.187606 (rank : 213)
Query Neighborhood Hits	211	Target Neighborhood Hits	804	Shared Neighborhood Hits	123
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.186695 (rank : 222)
Query Neighborhood Hits	211	Target Neighborhood Hits	838	Shared Neighborhood Hits	127
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.167806 (rank : 262)
Query Neighborhood Hits	211	Target Neighborhood Hits	1198	Shared Neighborhood Hits	126
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA4_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.135788 (rank : 323)
Query Neighborhood Hits	211	Target Neighborhood Hits	708	Shared Neighborhood Hits	99
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.142166 (rank : 309)
Query Neighborhood Hits	211	Target Neighborhood Hits	584	Shared Neighborhood Hits	100
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.200163 (rank : 197)
Query Neighborhood Hits	211	Target Neighborhood Hits	976	Shared Neighborhood Hits	129
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.207270 (rank : 186)
Query Neighborhood Hits	211	Target Neighborhood Hits	828	Shared Neighborhood Hits	137
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.176423 (rank : 240)
Query Neighborhood Hits	211	Target Neighborhood Hits	1018	Shared Neighborhood Hits	124
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.186872 (rank : 221)
Query Neighborhood Hits	211	Target Neighborhood Hits	919	Shared Neighborhood Hits	128
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB3_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.168074 (rank : 260)
Query Neighborhood Hits	211	Target Neighborhood Hits	461	Shared Neighborhood Hits	107
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.173536 (rank : 246)
Query Neighborhood Hits	211	Target Neighborhood Hits	444	Shared Neighborhood Hits	113
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.175608 (rank : 242)
Query Neighborhood Hits	211	Target Neighborhood Hits	715	Shared Neighborhood Hits	114
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC3_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.182759 (rank : 230)
Query Neighborhood Hits	211	Target Neighborhood Hits	588	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.185908 (rank : 225)
Query Neighborhood Hits	211	Target Neighborhood Hits	624	Shared Neighborhood Hits	121
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.117529 (rank : 345)
Query Neighborhood Hits	211	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.153082 (rank : 287)
Query Neighborhood Hits	211	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.137699 (rank : 318)
Query Neighborhood Hits	211	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.129369 (rank : 330)
Query Neighborhood Hits	211	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.126392 (rank : 334)
Query Neighborhood Hits	211	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.104056 (rank : 362)
Query Neighborhood Hits	211	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.091553 (rank : 380)
Query Neighborhood Hits	211	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.059033 (rank : 477)
Query Neighborhood Hits	211	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.068214 (rank : 448)
Query Neighborhood Hits	211	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.062824 (rank : 465)
Query Neighborhood Hits	211	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.078038 (rank : 418)
Query Neighborhood Hits	211	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.059249 (rank : 475)
Query Neighborhood Hits	211	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE4A_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.070013 (rank : 444)
Query Neighborhood Hits	211	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LDLR_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.186432 (rank : 223)
Query Neighborhood Hits	211	Target Neighborhood Hits	375	Shared Neighborhood Hits	107
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LORI_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.078450 (rank : 417)
Query Neighborhood Hits	211	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRC21_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.051398 (rank : 504)
Query Neighborhood Hits	211	Target Neighborhood Hits	462	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRP3_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.051874 (rank : 503)
Query Neighborhood Hits	211	Target Neighborhood Hits	280	Shared Neighborhood Hits	54
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.157145 (rank : 278)
Query Neighborhood Hits	211	Target Neighborhood Hits	355	Shared Neighborhood Hits	97
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.156115 (rank : 283)
Query Neighborhood Hits	211	Target Neighborhood Hits	351	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.082764 (rank : 399)
Query Neighborhood Hits	211	Target Neighborhood Hits	224	Shared Neighborhood Hits	56
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.085420 (rank : 392)
Query Neighborhood Hits	211	Target Neighborhood Hits	236	Shared Neighborhood Hits	63
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.090072 (rank : 383)
Query Neighborhood Hits	211	Target Neighborhood Hits	235	Shared Neighborhood Hits	61
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.087802 (rank : 387)
Query Neighborhood Hits	211	Target Neighborhood Hits	232	Shared Neighborhood Hits	59
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.168508 (rank : 259)
Query Neighborhood Hits	211	Target Neighborhood Hits	346	Shared Neighborhood Hits	94
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.177239 (rank : 237)
Query Neighborhood Hits	211	Target Neighborhood Hits	385	Shared Neighborhood Hits	98
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.255084 (rank : 106)
Query Neighborhood Hits	211	Target Neighborhood Hits	617	Shared Neighborhood Hits	126
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP4_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.257792 (rank : 102)
Query Neighborhood Hits	211	Target Neighborhood Hits	607	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYAM1_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.119910 (rank : 343)
Query Neighborhood Hits	211	Target Neighborhood Hits	332	Shared Neighborhood Hits	103
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.111288 (rank : 351)
Query Neighborhood Hits	211	Target Neighborhood Hits	378	Shared Neighborhood Hits	103
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.129526 (rank : 329)
Query Neighborhood Hits	211	Target Neighborhood Hits	390	Shared Neighborhood Hits	106
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MATN2_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.199106 (rank : 201)
Query Neighborhood Hits	211	Target Neighborhood Hits	365	Shared Neighborhood Hits	99
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.196850 (rank : 204)
Query Neighborhood Hits	211	Target Neighborhood Hits	356	Shared Neighborhood Hits	100
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.156966 (rank : 280)
Query Neighborhood Hits	211	Target Neighborhood Hits	268	Shared Neighborhood Hits	83
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.156288 (rank : 281)
Query Neighborhood Hits	211	Target Neighborhood Hits	261	Shared Neighborhood Hits	83
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.154840 (rank : 285)
Query Neighborhood Hits	211	Target Neighborhood Hits	287	Shared Neighborhood Hits	87
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.145610 (rank : 304)
Query Neighborhood Hits	211	Target Neighborhood Hits	277	Shared Neighborhood Hits	82
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCSP_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.059041 (rank : 476)
Query Neighborhood Hits	211	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEGF8_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.211134 (rank : 179)
Query Neighborhood Hits	211	Target Neighborhood Hits	528	Shared Neighborhood Hits	120
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.208071 (rank : 183)
Query Neighborhood Hits	211	Target Neighborhood Hits	520	Shared Neighborhood Hits	120
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.205284 (rank : 188)
Query Neighborhood Hits	211	Target Neighborhood Hits	557	Shared Neighborhood Hits	115
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEP1A_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.080803 (rank : 409)
Query Neighborhood Hits	211	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.082478 (rank : 402)
Query Neighborhood Hits	211	Target Neighborhood Hits	166	Shared Neighborhood Hits	68
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MFGM_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.088899 (rank : 384)
Query Neighborhood Hits	211	Target Neighborhood Hits	150	Shared Neighborhood Hits	67
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.186245 (rank : 224)
Query Neighborhood Hits	211	Target Neighborhood Hits	233	Shared Neighborhood Hits	106
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MMRN1_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.097677 (rank : 373)
Query Neighborhood Hits	211	Target Neighborhood Hits	636	Shared Neighborhood Hits	79
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MT3_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.077800 (rank : 421)
Query Neighborhood Hits	211	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.080102 (rank : 411)
Query Neighborhood Hits	211	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.083724 (rank : 397)
Query Neighborhood Hits	211	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.096919 (rank : 374)
Query Neighborhood Hits	211	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.068499 (rank : 447)
Query Neighborhood Hits	211	Target Neighborhood Hits	164	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC13_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.096770 (rank : 375)
Query Neighborhood Hits	211	Target Neighborhood Hits	447	Shared Neighborhood Hits	79
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC2_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.072821 (rank : 431)
Query Neighborhood Hits	211	Target Neighborhood Hits	906	Shared Neighborhood Hits	88
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.102661 (rank : 365)
Query Neighborhood Hits	211	Target Neighborhood Hits	1020	Shared Neighborhood Hits	108
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NELL2_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.254427 (rank : 107)
Query Neighborhood Hits	211	Target Neighborhood Hits	436	Shared Neighborhood Hits	127
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NET1_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.085343 (rank : 393)
Query Neighborhood Hits	211	Target Neighborhood Hits	149	Shared Neighborhood Hits	64
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.082695 (rank : 401)
Query Neighborhood Hits	211	Target Neighborhood Hits	151	Shared Neighborhood Hits	63
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET2_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.102835 (rank : 364)
Query Neighborhood Hits	211	Target Neighborhood Hits	194	Shared Neighborhood Hits	77
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.106859 (rank : 357)
Query Neighborhood Hits	211	Target Neighborhood Hits	193	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.105894 (rank : 359)
Query Neighborhood Hits	211	Target Neighborhood Hits	191	Shared Neighborhood Hits	78
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.103372 (rank : 363)
Query Neighborhood Hits	211	Target Neighborhood Hits	180	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NFX1_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.129841 (rank : 328)
Query Neighborhood Hits	211	Target Neighborhood Hits	405	Shared Neighborhood Hits	73
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.229179 (rank : 139)
Query Neighborhood Hits	211	Target Neighborhood Hits	329	Shared Neighborhood Hits	114
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.231252 (rank : 138)
Query Neighborhood Hits	211	Target Neighborhood Hits	335	Shared Neighborhood Hits	116
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.238396 (rank : 129)
Query Neighborhood Hits	211	Target Neighborhood Hits	456	Shared Neighborhood Hits	119
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.238464 (rank : 128)
Query Neighborhood Hits	211	Target Neighborhood Hits	338	Shared Neighborhood Hits	112
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NRX1A_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.120237 (rank : 342)
Query Neighborhood Hits	211	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.119800 (rank : 344)
Query Neighborhood Hits	211	Target Neighborhood Hits	164	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.104438 (rank : 360)
Query Neighborhood Hits	211	Target Neighborhood Hits	614	Shared Neighborhood Hits	70
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.109140 (rank : 355)
Query Neighborhood Hits	211	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NTNG1_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.164755 (rank : 267)
Query Neighborhood Hits	211	Target Neighborhood Hits	247	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.163795 (rank : 268)
Query Neighborhood Hits	211	Target Neighborhood Hits	246	Shared Neighborhood Hits	102
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.187082 (rank : 218)
Query Neighborhood Hits	211	Target Neighborhood Hits	276	Shared Neighborhood Hits	124
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.187446 (rank : 214)
Query Neighborhood Hits	211	Target Neighborhood Hits	276	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCSK5_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.072045 (rank : 435)
Query Neighborhood Hits	211	Target Neighborhood Hits	291	Shared Neighborhood Hits	87
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.061992 (rank : 468)
Query Neighborhood Hits	211	Target Neighborhood Hits	298	Shared Neighborhood Hits	73
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PERT_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.080539 (rank : 410)
Query Neighborhood Hits	211	Target Neighborhood Hits	221	Shared Neighborhood Hits	61
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.072346 (rank : 432)
Query Neighborhood Hits	211	Target Neighborhood Hits	221	Shared Neighborhood Hits	56
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGCA_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.079087 (rank : 414)
Query Neighborhood Hits	211	Target Neighborhood Hits	821	Shared Neighborhood Hits	98
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCB_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.106206 (rank : 358)
Query Neighborhood Hits	211	Target Neighborhood Hits	478	Shared Neighborhood Hits	89
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.112272 (rank : 349)
Query Neighborhood Hits	211	Target Neighborhood Hits	459	Shared Neighborhood Hits	91
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGH1_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.071235 (rank : 440)
Query Neighborhood Hits	211	Target Neighborhood Hits	91	Shared Neighborhood Hits	49
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.081258 (rank : 408)
Query Neighborhood Hits	211	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.083896 (rank : 396)
Query Neighborhood Hits	211	Target Neighborhood Hits	103	Shared Neighborhood Hits	56
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.087852 (rank : 386)
Query Neighborhood Hits	211	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PROC_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.086272 (rank : 391)
Query Neighborhood Hits	211	Target Neighborhood Hits	406	Shared Neighborhood Hits	107
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.099294 (rank : 370)
Query Neighborhood Hits	211	Target Neighborhood Hits	426	Shared Neighborhood Hits	111
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.214495 (rank : 170)
Query Neighborhood Hits	211	Target Neighborhood Hits	340	Shared Neighborhood Hits	116
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.215631 (rank : 169)
Query Neighborhood Hits	211	Target Neighborhood Hits	330	Shared Neighborhood Hits	112
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.167245 (rank : 263)
Query Neighborhood Hits	211	Target Neighborhood Hits	422	Shared Neighborhood Hits	111
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.163479 (rank : 269)
Query Neighborhood Hits	211	Target Neighborhood Hits	410	Shared Neighborhood Hits	109
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.221039 (rank : 160)
Query Neighborhood Hits	211	Target Neighborhood Hits	428	Shared Neighborhood Hits	108
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.221840 (rank : 157)
Query Neighborhood Hits	211	Target Neighborhood Hits	442	Shared Neighborhood Hits	109
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SO2A1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.067218 (rank : 452)
Query Neighborhood Hits	211	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2A1_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.069991 (rank : 445)
Query Neighborhood Hits	211	Target Neighborhood Hits	51	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2B1_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.054861 (rank : 492)
Query Neighborhood Hits	211	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

SO2B1_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.055685 (rank : 488)
Query Neighborhood Hits	211	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SO4A1_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.066863 (rank : 453)
Query Neighborhood Hits	211	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

SORL_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.130020 (rank : 327)
Query Neighborhood Hits	211	Target Neighborhood Hits	440	Shared Neighborhood Hits	90
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.138999 (rank : 313)
Query Neighborhood Hits	211	Target Neighborhood Hits	439	Shared Neighborhood Hits	101
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPRL1_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.165574 (rank : 266)
Query Neighborhood Hits	211	Target Neighborhood Hits	231	Shared Neighborhood Hits	38
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPRL1_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.145632 (rank : 303)
Query Neighborhood Hits	211	Target Neighborhood Hits	403	Shared Neighborhood Hits	37
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SREC2_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.282058 (rank : 72)
Query Neighborhood Hits	211	Target Neighborhood Hits	645	Shared Neighborhood Hits	127
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SSPO_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.144229 (rank : 305)
Query Neighborhood Hits	211	Target Neighborhood Hits	800	Shared Neighborhood Hits	129
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SUSD1_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.198900 (rank : 202)
Query Neighborhood Hits	211	Target Neighborhood Hits	285	Shared Neighborhood Hits	86
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.125516 (rank : 337)
Query Neighborhood Hits	211	Target Neighborhood Hits	132	Shared Neighborhood Hits	76
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.139556 (rank : 311)
Query Neighborhood Hits	211	Target Neighborhood Hits	146	Shared Neighborhood Hits	80
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.123085 (rank : 339)
Query Neighborhood Hits	211	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTA_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.059711 (rank : 473)
Query Neighborhood Hits	211	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.066378 (rank : 456)
Query Neighborhood Hits	211	Target Neighborhood Hits	244	Shared Neighborhood Hits	75
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TENN_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.150471 (rank : 292)
Query Neighborhood Hits	211	Target Neighborhood Hits	453	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.159352 (rank : 274)
Query Neighborhood Hits	211	Target Neighborhood Hits	484	Shared Neighborhood Hits	117
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TIE1_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.079430 (rank : 413)
Query Neighborhood Hits	211	Target Neighborhood Hits	1241	Shared Neighborhood Hits	120
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.065448 (rank : 458)
Query Neighborhood Hits	211	Target Neighborhood Hits	1192	Shared Neighborhood Hits	116
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.064002 (rank : 462)
Query Neighborhood Hits	211	Target Neighborhood Hits	1204	Shared Neighborhood Hits	116
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TLL1_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.056832 (rank : 484)
Query Neighborhood Hits	211	Target Neighborhood Hits	236	Shared Neighborhood Hits	55
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.059462 (rank : 474)
Query Neighborhood Hits	211	Target Neighborhood Hits	237	Shared Neighborhood Hits	56
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.059031 (rank : 478)
Query Neighborhood Hits	211	Target Neighborhood Hits	241	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.052085 (rank : 501)
Query Neighborhood Hits	211	Target Neighborhood Hits	240	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TPA_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.066507 (rank : 455)
Query Neighborhood Hits	211	Target Neighborhood Hits	324	Shared Neighborhood Hits	86
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRBM_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.221589 (rank : 159)
Query Neighborhood Hits	211	Target Neighborhood Hits	339	Shared Neighborhood Hits	102
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.212706 (rank : 177)
Query Neighborhood Hits	211	Target Neighborhood Hits	361	Shared Neighborhood Hits	105
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP1_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.137317 (rank : 319)
Query Neighborhood Hits	211	Target Neighborhood Hits	389	Shared Neighborhood Hits	103
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.138771 (rank : 314)
Query Neighborhood Hits	211	Target Neighborhood Hits	396	Shared Neighborhood Hits	103
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.127830 (rank : 331)
Query Neighborhood Hits	211	Target Neighborhood Hits	359	Shared Neighborhood Hits	98
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.125523 (rank : 336)
Query Neighborhood Hits	211	Target Neighborhood Hits	352	Shared Neighborhood Hits	97
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.170445 (rank : 255)
Query Neighborhood Hits	211	Target Neighborhood Hits	250	Shared Neighborhood Hits	88
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.173952 (rank : 245)
Query Neighborhood Hits	211	Target Neighborhood Hits	247	Shared Neighborhood Hits	90
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.197450 (rank : 203)
Query Neighborhood Hits	211	Target Neighborhood Hits	277	Shared Neighborhood Hits	104
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.199571 (rank : 199)
Query Neighborhood Hits	211	Target Neighborhood Hits	276	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROL1_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.071642 (rank : 438)
Query Neighborhood Hits	211	Target Neighborhood Hits	213	Shared Neighborhood Hits	57
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.078694 (rank : 416)
Query Neighborhood Hits	211	Target Neighborhood Hits	235	Shared Neighborhood Hits	59
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.213169 (rank : 175)
Query Neighborhood Hits	211	Target Neighborhood Hits	284	Shared Neighborhood Hits	107
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.213838 (rank : 173)
Query Neighborhood Hits	211	Target Neighborhood Hits	276	Shared Neighborhood Hits	105
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.153641 (rank : 286)
Query Neighborhood Hits	211	Target Neighborhood Hits	600	Shared Neighborhood Hits	114
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.158637 (rank : 276)
Query Neighborhood Hits	211	Target Neighborhood Hits	626	Shared Neighborhood Hits	113
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VASN_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.079536 (rank : 412)
Query Neighborhood Hits	211	Target Neighborhood Hits	449	Shared Neighborhood Hits	88
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VASN_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.071984 (rank : 436)
Query Neighborhood Hits	211	Target Neighborhood Hits	426	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VEGFC_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.087264 (rank : 389)
Query Neighborhood Hits	211	Target Neighborhood Hits	119	Shared Neighborhood Hits	55
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VLDLR_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.184889 (rank : 227)
Query Neighborhood Hits	211	Target Neighborhood Hits	383	Shared Neighborhood Hits	108
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.179537 (rank : 232)
Query Neighborhood Hits	211	Target Neighborhood Hits	360	Shared Neighborhood Hits	106
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.111557 (rank : 350)
Query Neighborhood Hits	211	Target Neighborhood Hits	396	Shared Neighborhood Hits	100
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.100320 (rank : 367)
Query Neighborhood Hits	211	Target Neighborhood Hits	381	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WFDC3_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.064213 (rank : 461)
Query Neighborhood Hits	211	Target Neighborhood Hits	138	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ZAN_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.222337 (rank : 155)
Query Neighborhood Hits	211	Target Neighborhood Hits	808	Shared Neighborhood Hits	140
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

TEFF2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	211	Target Neighborhood Hits	211	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
NC score	0.998647 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	211	Target Neighborhood Hits	214	Shared Neighborhood Hits	209
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

BTC_MOUSE
NC score	0.551945 (rank : 3)	θ value	1.9326e-10 (rank : 6)
Query Neighborhood Hits	211	Target Neighborhood Hits	67	Shared Neighborhood Hits	60
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

FST_MOUSE
NC score	0.527571 (rank : 4)	θ value	3.52202e-12 (rank : 4)
Query Neighborhood Hits	211	Target Neighborhood Hits	146	Shared Neighborhood Hits	93
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_HUMAN
NC score	0.524410 (rank : 5)	θ value	7.84624e-12 (rank : 5)
Query Neighborhood Hits	211	Target Neighborhood Hits	129	Shared Neighborhood Hits	88
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

BTC_HUMAN
NC score	0.519778 (rank : 6)	θ value	2.79066e-09 (rank : 8)
Query Neighborhood Hits	211	Target Neighborhood Hits	70	Shared Neighborhood Hits	55
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

TGFA_HUMAN
NC score	0.508741 (rank : 7)	θ value	1.80886e-08 (rank : 9)
Query Neighborhood Hits	211	Target Neighborhood Hits	61	Shared Neighborhood Hits	56
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TGFA_MOUSE
NC score	0.500924 (rank : 8)	θ value	3.08544e-08 (rank : 10)
Query Neighborhood Hits	211	Target Neighborhood Hits	62	Shared Neighborhood Hits	53
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

EREG_HUMAN
NC score	0.497252 (rank : 9)	θ value	4.45536e-07 (rank : 18)
Query Neighborhood Hits	211	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EPGN_MOUSE
NC score	0.491926 (rank : 10)	θ value	3.41135e-07 (rank : 15)
Query Neighborhood Hits	211	Target Neighborhood Hits	63	Shared Neighborhood Hits	57
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

FSTL3_HUMAN
NC score	0.487805 (rank : 11)	θ value	5.81887e-07 (rank : 20)
Query Neighborhood Hits	211	Target Neighborhood Hits	162	Shared Neighborhood Hits	101
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

EREG_MOUSE
NC score	0.485389 (rank : 12)	θ value	1.99992e-07 (rank : 13)
Query Neighborhood Hits	211	Target Neighborhood Hits	65	Shared Neighborhood Hits	55
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

FSTL3_MOUSE
NC score	0.482588 (rank : 13)	θ value	2.61198e-07 (rank : 14)
Query Neighborhood Hits	211	Target Neighborhood Hits	152	Shared Neighborhood Hits	94
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

AGRIN_HUMAN
NC score	0.472503 (rank : 14)	θ value	4.43474e-23 (rank : 3)
Query Neighborhood Hits	211	Target Neighborhood Hits	582	Shared Neighborhood Hits	182
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

EPGN_HUMAN
NC score	0.453334 (rank : 15)	θ value	0.000121331 (rank : 38)
Query Neighborhood Hits	211	Target Neighborhood Hits	59	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

HBEGF_HUMAN
NC score	0.441499 (rank : 16)	θ value	6.43352e-06 (rank : 26)
Query Neighborhood Hits	211	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

HBEGF_MOUSE
NC score	0.424654 (rank : 17)	θ value	1.43324e-05 (rank : 31)
Query Neighborhood Hits	211	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

AREG_HUMAN
NC score	0.422359 (rank : 18)	θ value	2.21117e-06 (rank : 22)
Query Neighborhood Hits	211	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	P15514	Gene names	AREG
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Colorectum cell-derived growth factor) (CRDGF).

FSTL1_HUMAN
NC score	0.418745 (rank : 19)	θ value	1.43324e-05 (rank : 29)
Query Neighborhood Hits	211	Target Neighborhood Hits	68	Shared Neighborhood Hits	50
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
NC score	0.417095 (rank : 20)	θ value	1.43324e-05 (rank : 30)
Query Neighborhood Hits	211	Target Neighborhood Hits	74	Shared Neighborhood Hits	50
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

AREG_MOUSE
NC score	0.407038 (rank : 21)	θ value	1.87187e-05 (rank : 33)
Query Neighborhood Hits	211	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	P31955	Gene names	Areg, Sdgf
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Schwannoma-derived growth factor) (SDGF).

NRG4_MOUSE
NC score	0.393777 (rank : 22)	θ value	0.00390308 (rank : 54)
Query Neighborhood Hits	211	Target Neighborhood Hits	79	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_HUMAN
NC score	0.390077 (rank : 23)	θ value	0.0330416 (rank : 83)
Query Neighborhood Hits	211	Target Neighborhood Hits	85	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

JAG1_MOUSE
NC score	0.350277 (rank : 24)	θ value	1.09739e-05 (rank : 28)
Query Neighborhood Hits	211	Target Neighborhood Hits	518	Shared Neighborhood Hits	145
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

IPK1_HUMAN
NC score	0.349832 (rank : 25)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	211	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

DNER_MOUSE
NC score	0.349195 (rank : 26)	θ value	0.00298849 (rank : 52)
Query Neighborhood Hits	211	Target Neighborhood Hits	413	Shared Neighborhood Hits	142
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

JAG1_HUMAN
NC score	0.347734 (rank : 27)	θ value	7.1131e-05 (rank : 35)
Query Neighborhood Hits	211	Target Neighborhood Hits	514	Shared Neighborhood Hits	143
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

DNER_HUMAN
NC score	0.345728 (rank : 28)	θ value	0.0252991 (rank : 76)
Query Neighborhood Hits	211	Target Neighborhood Hits	460	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DLL4_MOUSE
NC score	0.342523 (rank : 29)	θ value	0.0252991 (rank : 75)
Query Neighborhood Hits	211	Target Neighborhood Hits	440	Shared Neighborhood Hits	142
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG2_MOUSE
NC score	0.341669 (rank : 30)	θ value	0.0330416 (rank : 82)
Query Neighborhood Hits	211	Target Neighborhood Hits	504	Shared Neighborhood Hits	145
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DLL4_HUMAN
NC score	0.339884 (rank : 31)	θ value	0.0148317 (rank : 67)
Query Neighborhood Hits	211	Target Neighborhood Hits	435	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

CRUM1_HUMAN
NC score	0.339498 (rank : 32)	θ value	0.00134147 (rank : 44)
Query Neighborhood Hits	211	Target Neighborhood Hits	457	Shared Neighborhood Hits	141
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

JAG2_HUMAN
NC score	0.338398 (rank : 33)	θ value	0.00869519 (rank : 60)
Query Neighborhood Hits	211	Target Neighborhood Hits	491	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NOTC1_MOUSE
NC score	0.333451 (rank : 34)	θ value	7.1131e-05 (rank : 36)
Query Neighborhood Hits	211	Target Neighborhood Hits	916	Shared Neighborhood Hits	154
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DLL1_HUMAN
NC score	0.332534 (rank : 35)	θ value	0.0431538 (rank : 85)
Query Neighborhood Hits	211	Target Neighborhood Hits	455	Shared Neighborhood Hits	137
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
NC score	0.332273 (rank : 36)	θ value	0.0252991 (rank : 74)
Query Neighborhood Hits	211	Target Neighborhood Hits	456	Shared Neighborhood Hits	138
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

CRUM1_MOUSE
NC score	0.330770 (rank : 37)	θ value	0.125558 (rank : 99)
Query Neighborhood Hits	211	Target Neighborhood Hits	444	Shared Neighborhood Hits	145
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

NOTC1_HUMAN
NC score	0.328163 (rank : 38)	θ value	3.41135e-07 (rank : 16)
Query Neighborhood Hits	211	Target Neighborhood Hits	906	Shared Neighborhood Hits	151
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
NC score	0.326070 (rank : 39)	θ value	8.40245e-06 (rank : 27)
Query Neighborhood Hits	211	Target Neighborhood Hits	1069	Shared Neighborhood Hits	158
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.325707 (rank : 40)	θ value	1.69304e-06 (rank : 21)
Query Neighborhood Hits	211	Target Neighborhood Hits	1113	Shared Neighborhood Hits	156
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

EGFL9_HUMAN
NC score	0.325042 (rank : 41)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	211	Target Neighborhood Hits	365	Shared Neighborhood Hits	130
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
NC score	0.323783 (rank : 42)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	211	Target Neighborhood Hits	379	Shared Neighborhood Hits	128
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

SMOC1_HUMAN
NC score	0.323678 (rank : 43)	θ value	3.41135e-07 (rank : 17)
Query Neighborhood Hits	211	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

NOTC3_HUMAN
NC score	0.323598 (rank : 44)	θ value	1.43324e-05 (rank : 32)
Query Neighborhood Hits	211	Target Neighborhood Hits	1062	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SMOC1_MOUSE
NC score	0.323056 (rank : 45)	θ value	3.77169e-06 (rank : 25)
Query Neighborhood Hits	211	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

EGF_MOUSE
NC score	0.321458 (rank : 46)	θ value	9.59137e-10 (rank : 7)
Query Neighborhood Hits	211	Target Neighborhood Hits	358	Shared Neighborhood Hits	134
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

NOTC3_MOUSE
NC score	0.320260 (rank : 47)	θ value	0.000121331 (rank : 39)
Query Neighborhood Hits	211	Target Neighborhood Hits	975	Shared Neighborhood Hits	152
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

DLL3_MOUSE
NC score	0.318333 (rank : 48)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	211	Target Neighborhood Hits	399	Shared Neighborhood Hits	135
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL3_HUMAN
NC score	0.316905 (rank : 49)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	211	Target Neighborhood Hits	419	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

CRUM2_HUMAN
NC score	0.313209 (rank : 50)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	211	Target Neighborhood Hits	453	Shared Neighborhood Hits	138
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DLK_MOUSE
NC score	0.309337 (rank : 51)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	211	Target Neighborhood Hits	374	Shared Neighborhood Hits	127
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLK_HUMAN
NC score	0.308739 (rank : 52)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	211	Target Neighborhood Hits	401	Shared Neighborhood Hits	130
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

NOTC4_MOUSE
NC score	0.307698 (rank : 53)	θ value	0.00134147 (rank : 45)
Query Neighborhood Hits	211	Target Neighborhood Hits	872	Shared Neighborhood Hits	155
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

WIF1_MOUSE
NC score	0.306967 (rank : 54)	θ value	0.47712 (rank : 126)
Query Neighborhood Hits	211	Target Neighborhood Hits	393	Shared Neighborhood Hits	127
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NOTC4_HUMAN
NC score	0.304325 (rank : 55)	θ value	0.00869519 (rank : 61)
Query Neighborhood Hits	211	Target Neighborhood Hits	905	Shared Neighborhood Hits	153
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

EGF_HUMAN
NC score	0.303907 (rank : 56)	θ value	5.81887e-07 (rank : 19)
Query Neighborhood Hits	211	Target Neighborhood Hits	343	Shared Neighborhood Hits	129
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

MEGF6_HUMAN
NC score	0.301751 (rank : 57)	θ value	0.00102713 (rank : 41)
Query Neighborhood Hits	211	Target Neighborhood Hits	671	Shared Neighborhood Hits	152
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

ISK5_HUMAN
NC score	0.300037 (rank : 58)	θ value	0.00020696 (rank : 40)
Query Neighborhood Hits	211	Target Neighborhood Hits	89	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

ISK4_HUMAN
NC score	0.299385 (rank : 59)	θ value	0.0736092 (rank : 93)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

STAB2_MOUSE
NC score	0.299184 (rank : 60)	θ value	0.00390308 (rank : 56)
Query Neighborhood Hits	211	Target Neighborhood Hits	528	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SREC2_MOUSE
NC score	0.297913 (rank : 61)	θ value	0.0563607 (rank : 89)
Query Neighborhood Hits	211	Target Neighborhood Hits	605	Shared Neighborhood Hits	131
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SMOC2_MOUSE
NC score	0.297494 (rank : 62)	θ value	5.44631e-05 (rank : 34)
Query Neighborhood Hits	211	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

WIF1_HUMAN
NC score	0.297155 (rank : 63)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	211	Target Neighborhood Hits	392	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ISK7_HUMAN
NC score	0.297122 (rank : 64)	θ value	0.0113563 (rank : 64)
Query Neighborhood Hits	211	Target Neighborhood Hits	31	Shared Neighborhood Hits	29
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

STAB1_MOUSE
NC score	0.295992 (rank : 65)	θ value	0.00390308 (rank : 55)
Query Neighborhood Hits	211	Target Neighborhood Hits	566	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

SMOC2_HUMAN
NC score	0.295073 (rank : 66)	θ value	7.1131e-05 (rank : 37)
Query Neighborhood Hits	211	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

STAB1_HUMAN
NC score	0.291303 (rank : 67)	θ value	0.0252991 (rank : 79)
Query Neighborhood Hits	211	Target Neighborhood Hits	546	Shared Neighborhood Hits	141
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_HUMAN
NC score	0.290962 (rank : 68)	θ value	0.365318 (rank : 123)
Query Neighborhood Hits	211	Target Neighborhood Hits	534	Shared Neighborhood Hits	140
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

NRG1_HUMAN
NC score	0.288714 (rank : 69)	θ value	0.0148317 (rank : 69)
Query Neighborhood Hits	211	Target Neighborhood Hits	285	Shared Neighborhood Hits	87
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

SREC_HUMAN
NC score	0.288136 (rank : 70)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	211	Target Neighborhood Hits	645	Shared Neighborhood Hits	138
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ISK6_MOUSE
NC score	0.282865 (rank : 71)	θ value	0.21417 (rank : 106)
Query Neighborhood Hits	211	Target Neighborhood Hits	37	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

SREC2_HUMAN
NC score	0.282058 (rank : 72)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	211	Target Neighborhood Hits	645	Shared Neighborhood Hits	127
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

FBN2_HUMAN
NC score	0.279648 (rank : 73)	θ value	0.0330416 (rank : 81)
Query Neighborhood Hits	211	Target Neighborhood Hits	560	Shared Neighborhood Hits	143
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

NRG2_MOUSE
NC score	0.279415 (rank : 74)	θ value	0.00228821 (rank : 50)
Query Neighborhood Hits	211	Target Neighborhood Hits	392	Shared Neighborhood Hits	96
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

KRA59_HUMAN
NC score	0.278584 (rank : 75)	θ value	0.279714 (rank : 114)
Query Neighborhood Hits	211	Target Neighborhood Hits	310	Shared Neighborhood Hits	96
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

FBN2_MOUSE
NC score	0.276784 (rank : 76)	θ value	0.0961366 (rank : 96)
Query Neighborhood Hits	211	Target Neighborhood Hits	549	Shared Neighborhood Hits	141
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
NC score	0.274402 (rank : 77)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	211	Target Neighborhood Hits	543	Shared Neighborhood Hits	139
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

ISK4_MOUSE
NC score	0.273419 (rank : 78)	θ value	0.125558 (rank : 100)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

NAGPA_HUMAN
NC score	0.271186 (rank : 79)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	211	Target Neighborhood Hits	282	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ISK6_HUMAN
NC score	0.269376 (rank : 80)	θ value	0.47712 (rank : 124)
Query Neighborhood Hits	211	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

NELL1_HUMAN
NC score	0.267757 (rank : 81)	θ value	0.47712 (rank : 125)
Query Neighborhood Hits	211	Target Neighborhood Hits	451	Shared Neighborhood Hits	134
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

TENA_MOUSE
NC score	0.267721 (rank : 82)	θ value	0.00665767 (rank : 58)
Query Neighborhood Hits	211	Target Neighborhood Hits	596	Shared Neighborhood Hits	135
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

NELL2_HUMAN
NC score	0.267382 (rank : 83)	θ value	0.21417 (rank : 107)
Query Neighborhood Hits	211	Target Neighborhood Hits	449	Shared Neighborhood Hits	130
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

LTBP3_HUMAN
NC score	0.266637 (rank : 84)	θ value	0.125558 (rank : 101)
Query Neighborhood Hits	211	Target Neighborhood Hits	502	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TENA_HUMAN
NC score	0.266289 (rank : 85)	θ value	0.00228821 (rank : 51)
Query Neighborhood Hits	211	Target Neighborhood Hits	631	Shared Neighborhood Hits	136
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

FBN1_HUMAN
NC score	0.265745 (rank : 86)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	211	Target Neighborhood Hits	557	Shared Neighborhood Hits	140
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

TENX_HUMAN
NC score	0.265184 (rank : 87)	θ value	0.0563607 (rank : 90)
Query Neighborhood Hits	211	Target Neighborhood Hits	789	Shared Neighborhood Hits	135
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

SLIT2_HUMAN
NC score	0.265182 (rank : 88)	θ value	0.00298849 (rank : 53)
Query Neighborhood Hits	211	Target Neighborhood Hits	708	Shared Neighborhood Hits	150
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

FBN1_MOUSE
NC score	0.265170 (rank : 89)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	211	Target Neighborhood Hits	563	Shared Neighborhood Hits	142
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

SLIT1_HUMAN
NC score	0.264661 (rank : 90)	θ value	0.00509761 (rank : 57)
Query Neighborhood Hits	211	Target Neighborhood Hits	700	Shared Neighborhood Hits	145
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

KRA51_HUMAN
NC score	0.264385 (rank : 91)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	211	Target Neighborhood Hits	288	Shared Neighborhood Hits	102
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
NC score	0.263537 (rank : 92)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	211	Target Neighborhood Hits	331	Shared Neighborhood Hits	107
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

SLIT2_MOUSE
NC score	0.262136 (rank : 93)	θ value	0.00102713 (rank : 42)
Query Neighborhood Hits	211	Target Neighborhood Hits	684	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NRG2_HUMAN
NC score	0.261372 (rank : 94)	θ value	0.00228821 (rank : 49)
Query Neighborhood Hits	211	Target Neighborhood Hits	419	Shared Neighborhood Hits	87
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

SLIT1_MOUSE
NC score	0.260452 (rank : 95)	θ value	0.0961366 (rank : 98)
Query Neighborhood Hits	211	Target Neighborhood Hits	715	Shared Neighborhood Hits	146
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

CUBN_HUMAN
NC score	0.259650 (rank : 96)	θ value	0.0736092 (rank : 92)
Query Neighborhood Hits	211	Target Neighborhood Hits	482	Shared Neighborhood Hits	139
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

LTB1L_MOUSE
NC score	0.259316 (rank : 97)	θ value	0.279714 (rank : 115)
Query Neighborhood Hits	211	Target Neighborhood Hits	514	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SLIT3_MOUSE
NC score	0.259179 (rank : 98)	θ value	0.0113563 (rank : 66)
Query Neighborhood Hits	211	Target Neighborhood Hits	700	Shared Neighborhood Hits	150
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SLIT3_HUMAN
NC score	0.259075 (rank : 99)	θ value	0.00175202 (rank : 48)
Query Neighborhood Hits	211	Target Neighborhood Hits	682	Shared Neighborhood Hits	145
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

LTB1S_MOUSE
NC score	0.258827 (rank : 100)	θ value	0.279714 (rank : 116)
Query Neighborhood Hits	211	Target Neighborhood Hits	479	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
NC score	0.258111 (rank : 101)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	211	Target Neighborhood Hits	552	Shared Neighborhood Hits	129
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP4_MOUSE
NC score	0.257792 (rank : 102)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	211	Target Neighborhood Hits	607	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

KRA55_HUMAN
NC score	0.257570 (rank : 103)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	211	Target Neighborhood Hits	257	Shared Neighborhood Hits	96
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LTB1S_HUMAN
NC score	0.256505 (rank : 104)	θ value	0.62314 (rank : 130)
Query Neighborhood Hits	211	Target Neighborhood Hits	502	Shared Neighborhood Hits	131
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_MOUSE
NC score	0.256491 (rank : 105)	θ value	3.0926 (rank : 162)
Query Neighborhood Hits	211	Target Neighborhood Hits	475	Shared Neighborhood Hits	127
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP2_MOUSE
NC score	0.255084 (rank : 106)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	211	Target Neighborhood Hits	617	Shared Neighborhood Hits	126
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NELL2_MOUSE
NC score	0.254427 (rank : 107)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	211	Target Neighborhood Hits	436	Shared Neighborhood Hits	127
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

ITB5_MOUSE
NC score	0.253950 (rank : 108)	θ value	0.00175202 (rank : 47)
Query Neighborhood Hits	211	Target Neighborhood Hits	329	Shared Neighborhood Hits	125
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB7_HUMAN
NC score	0.253800 (rank : 109)	θ value	0.0113563 (rank : 65)
Query Neighborhood Hits	211	Target Neighborhood Hits	290	Shared Neighborhood Hits	120
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LTB1L_HUMAN
NC score	0.253153 (rank : 110)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	211	Target Neighborhood Hits	553	Shared Neighborhood Hits	130
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ISK3_MOUSE
NC score	0.253028 (rank : 111)	θ value	0.279714 (rank : 111)
Query Neighborhood Hits	211	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

KR104_HUMAN
NC score	0.252885 (rank : 112)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	211	Target Neighborhood Hits	313	Shared Neighborhood Hits	107
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

CUBN_MOUSE
NC score	0.251964 (rank : 113)	θ value	0.813845 (rank : 133)
Query Neighborhood Hits	211	Target Neighborhood Hits	477	Shared Neighborhood Hits	135
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

NAGPA_MOUSE
NC score	0.251020 (rank : 114)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	211	Target Neighborhood Hits	308	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ITB7_MOUSE
NC score	0.249966 (rank : 115)	θ value	0.0431538 (rank : 87)
Query Neighborhood Hits	211	Target Neighborhood Hits	277	Shared Neighborhood Hits	117
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB5_HUMAN
NC score	0.249218 (rank : 116)	θ value	0.0193708 (rank : 71)
Query Neighborhood Hits	211	Target Neighborhood Hits	310	Shared Neighborhood Hits	122
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB3_HUMAN
NC score	0.248783 (rank : 117)	θ value	0.0252991 (rank : 77)
Query Neighborhood Hits	211	Target Neighborhood Hits	325	Shared Neighborhood Hits	123
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KRA58_HUMAN
NC score	0.246741 (rank : 118)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	211	Target Neighborhood Hits	324	Shared Neighborhood Hits	103
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

EDIL3_MOUSE
NC score	0.246661 (rank : 119)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	211	Target Neighborhood Hits	317	Shared Neighborhood Hits	116
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FSTL4_MOUSE
NC score	0.245801 (rank : 120)	θ value	2.88788e-06 (rank : 23)
Query Neighborhood Hits	211	Target Neighborhood Hits	333	Shared Neighborhood Hits	53
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
NC score	0.243029 (rank : 121)	θ value	6.87365e-08 (rank : 11)
Query Neighborhood Hits	211	Target Neighborhood Hits	347	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

LRP1B_HUMAN
NC score	0.242710 (rank : 122)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	211	Target Neighborhood Hits	602	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
NC score	0.241774 (rank : 123)	θ value	0.163984 (rank : 104)
Query Neighborhood Hits	211	Target Neighborhood Hits	617	Shared Neighborhood Hits	151
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

ITB3_MOUSE
NC score	0.241038 (rank : 124)	θ value	0.163984 (rank : 103)
Query Neighborhood Hits	211	Target Neighborhood Hits	319	Shared Neighborhood Hits	119
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

FSTL5_MOUSE
NC score	0.240401 (rank : 125)	θ value	1.53129e-07 (rank : 12)
Query Neighborhood Hits	211	Target Neighborhood Hits	355	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

ITB2_MOUSE
NC score	0.240235 (rank : 126)	θ value	0.279714 (rank : 112)
Query Neighborhood Hits	211	Target Neighborhood Hits	326	Shared Neighborhood Hits	122
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

FSTL4_HUMAN
NC score	0.239998 (rank : 127)	θ value	3.77169e-06 (rank : 24)
Query Neighborhood Hits	211	Target Neighborhood Hits	344	Shared Neighborhood Hits	52
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

NID2_MOUSE
NC score	0.238464 (rank : 128)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	211	Target Neighborhood Hits	338	Shared Neighborhood Hits	112
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID2_HUMAN
NC score	0.238396 (rank : 129)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	211	Target Neighborhood Hits	456	Shared Neighborhood Hits	119
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LRP1B_MOUSE
NC score	0.238201 (rank : 130)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	211	Target Neighborhood Hits	606	Shared Neighborhood Hits	151
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KR106_HUMAN
NC score	0.237751 (rank : 131)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	211	Target Neighborhood Hits	347	Shared Neighborhood Hits	114
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
NC score	0.236559 (rank : 132)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	211	Target Neighborhood Hits	330	Shared Neighborhood Hits	111
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

SPRC_HUMAN
NC score	0.235408 (rank : 133)	θ value	0.0330416 (rank : 84)
Query Neighborhood Hits	211	Target Neighborhood Hits	45	Shared Neighborhood Hits	39
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

EDIL3_HUMAN
NC score	0.234502 (rank : 134)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	211	Target Neighborhood Hits	292	Shared Neighborhood Hits	108
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

SPRC_MOUSE
NC score	0.232627 (rank : 135)	θ value	0.0736092 (rank : 95)
Query Neighborhood Hits	211	Target Neighborhood Hits	46	Shared Neighborhood Hits	40
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

TICN2_MOUSE
NC score	0.232395 (rank : 136)	θ value	0.00665767 (rank : 59)
Query Neighborhood Hits	211	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN3_MOUSE
NC score	0.231519 (rank : 137)	θ value	0.00869519 (rank : 63)
Query Neighborhood Hits	211	Target Neighborhood Hits	83	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

NID1_MOUSE
NC score	0.231252 (rank : 138)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	211	Target Neighborhood Hits	335	Shared Neighborhood Hits	116
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_HUMAN
NC score	0.229179 (rank : 139)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	211	Target Neighborhood Hits	329	Shared Neighborhood Hits	114
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

FBLN2_HUMAN
NC score	0.228765 (rank : 140)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	211	Target Neighborhood Hits	392	Shared Neighborhood Hits	113
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

EGFL7_HUMAN
NC score	0.228433 (rank : 141)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	211	Target Neighborhood Hits	325	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

ITB6_MOUSE
NC score	0.228339 (rank : 142)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	211	Target Neighborhood Hits	341	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

IPK2_HUMAN
NC score	0.227964 (rank : 143)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	211	Target Neighborhood Hits	30	Shared Neighborhood Hits	28
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

FBLN2_MOUSE
NC score	0.226759 (rank : 144)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	211	Target Neighborhood Hits	505	Shared Neighborhood Hits	112
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

EGFL7_MOUSE
NC score	0.226308 (rank : 145)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	211	Target Neighborhood Hits	287	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

CREL1_HUMAN
NC score	0.226125 (rank : 146)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	211	Target Neighborhood Hits	441	Shared Neighborhood Hits	108
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

TICN3_HUMAN
NC score	0.225894 (rank : 147)	θ value	0.00869519 (rank : 62)
Query Neighborhood Hits	211	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

ITB6_HUMAN
NC score	0.224869 (rank : 148)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	211	Target Neighborhood Hits	318	Shared Neighborhood Hits	113
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KRA57_HUMAN
NC score	0.224859 (rank : 149)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	211	Target Neighborhood Hits	269	Shared Neighborhood Hits	91
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

C1QR1_MOUSE
NC score	0.224491 (rank : 150)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	211	Target Neighborhood Hits	342	Shared Neighborhood Hits	112
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

TICN2_HUMAN
NC score	0.223743 (rank : 151)	θ value	0.0148317 (rank : 70)
Query Neighborhood Hits	211	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

CREL1_MOUSE
NC score	0.223424 (rank : 152)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	211	Target Neighborhood Hits	524	Shared Neighborhood Hits	112
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

ITB2_HUMAN
NC score	0.223173 (rank : 153)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	211	Target Neighborhood Hits	282	Shared Neighborhood Hits	111
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

C1QR1_HUMAN
NC score	0.222908 (rank : 154)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	211	Target Neighborhood Hits	493	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

ZAN_MOUSE
NC score	0.222337 (rank : 155)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	211	Target Neighborhood Hits	808	Shared Neighborhood Hits	140
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ITB1_HUMAN
NC score	0.222235 (rank : 156)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	211	Target Neighborhood Hits	298	Shared Neighborhood Hits	113
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

SCUB3_MOUSE
NC score	0.221840 (rank : 157)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	211	Target Neighborhood Hits	442	Shared Neighborhood Hits	109
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

GAS6_MOUSE
NC score	0.221768 (rank : 158)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	211	Target Neighborhood Hits	343	Shared Neighborhood Hits	113
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TRBM_HUMAN
NC score	0.221589 (rank : 159)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	211	Target Neighborhood Hits	339	Shared Neighborhood Hits	102
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

SCUB3_HUMAN
NC score	0.221039 (rank : 160)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	211	Target Neighborhood Hits	428	Shared Neighborhood Hits	108
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SMDF_HUMAN
NC score	0.220405 (rank : 161)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	211	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

EGFL8_MOUSE
NC score	0.219970 (rank : 162)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	211	Target Neighborhood Hits	266	Shared Neighborhood Hits	97
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

FBLN1_MOUSE
NC score	0.219734 (rank : 163)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	211	Target Neighborhood Hits	329	Shared Neighborhood Hits	104
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

HHIP_HUMAN
NC score	0.219635 (rank : 164)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	211	Target Neighborhood Hits	249	Shared Neighborhood Hits	108
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

FBLN1_HUMAN
NC score	0.218733 (rank : 165)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	211	Target Neighborhood Hits	324	Shared Neighborhood Hits	106
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

GAS6_HUMAN
NC score	0.218649 (rank : 166)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	211	Target Neighborhood Hits	348	Shared Neighborhood Hits	113
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITB1_MOUSE
NC score	0.217873 (rank : 167)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	211	Target Neighborhood Hits	283	Shared Neighborhood Hits	112
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

EGFL8_HUMAN
NC score	0.216054 (rank : 168)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	211	Target Neighborhood Hits	270	Shared Neighborhood Hits	96
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

PROS_MOUSE
NC score	0.215631 (rank : 169)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	211	Target Neighborhood Hits	330	Shared Neighborhood Hits	112
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_HUMAN
NC score	0.214495 (rank : 170)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	211	Target Neighborhood Hits	340	Shared Neighborhood Hits	116
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

HHIP_MOUSE
NC score	0.214470 (rank : 171)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	211	Target Neighborhood Hits	219	Shared Neighborhood Hits	105
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

RECK_HUMAN
NC score	0.214386 (rank : 172)	θ value	0.163984 (rank : 105)
Query Neighborhood Hits	211	Target Neighborhood Hits	189	Shared Neighborhood Hits	95
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

UROM_MOUSE
NC score	0.213838 (rank : 173)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	211	Target Neighborhood Hits	276	Shared Neighborhood Hits	105
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FBLN5_HUMAN
NC score	0.213606 (rank : 174)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	211	Target Neighborhood Hits	329	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

UROM_HUMAN
NC score	0.213169 (rank : 175)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	211	Target Neighborhood Hits	284	Shared Neighborhood Hits	107
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FBLN4_HUMAN
NC score	0.212980 (rank : 176)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	211	Target Neighborhood Hits	278	Shared Neighborhood Hits	97
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

TRBM_MOUSE
NC score	0.212706 (rank : 177)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	211	Target Neighborhood Hits	361	Shared Neighborhood Hits	105
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ITB8_HUMAN
NC score	0.211238 (rank : 178)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	211	Target Neighborhood Hits	280	Shared Neighborhood Hits	110
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

MEGF8_HUMAN
NC score	0.211134 (rank : 179)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	211	Target Neighborhood Hits	528	Shared Neighborhood Hits	120
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_MOUSE
NC score	0.211036 (rank : 180)	θ value	0.279714 (rank : 117)
Query Neighborhood Hits	211	Target Neighborhood Hits	896	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

FBLN5_MOUSE
NC score	0.210636 (rank : 181)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	211	Target Neighborhood Hits	317	Shared Neighborhood Hits	101
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

KR171_HUMAN
NC score	0.208144 (rank : 182)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	211	Target Neighborhood Hits	144	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

MEGF8_MOUSE
NC score	0.208071 (rank : 183)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	211	Target Neighborhood Hits	520	Shared Neighborhood Hits	120
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

FBLN4_MOUSE
NC score	0.207911 (rank : 184)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	211	Target Neighborhood Hits	270	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

LAMB2_HUMAN
NC score	0.207503 (rank : 185)	θ value	0.62314 (rank : 128)
Query Neighborhood Hits	211	Target Neighborhood Hits	692	Shared Neighborhood Hits	124
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMA5_MOUSE
NC score	0.207270 (rank : 186)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	211	Target Neighborhood Hits	828	Shared Neighborhood Hits	137
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

KRA54_HUMAN
NC score	0.207203 (rank : 187)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	211	Target Neighborhood Hits	270	Shared Neighborhood Hits	89
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

MEGF9_HUMAN
NC score	0.205284 (rank : 188)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	211	Target Neighborhood Hits	557	Shared Neighborhood Hits	115
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

FBLN3_HUMAN
NC score	0.203444 (rank : 189)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	211	Target Neighborhood Hits	293	Shared Neighborhood Hits	96
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
NC score	0.203308 (rank : 190)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	211	Target Neighborhood Hits	279	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

KR101_HUMAN
NC score	0.202976 (rank : 191)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	211	Target Neighborhood Hits	261	Shared Neighborhood Hits	93
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

LAMB2_MOUSE
NC score	0.202896 (rank : 192)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	211	Target Neighborhood Hits	722	Shared Neighborhood Hits	129
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

KR511_HUMAN
NC score	0.202757 (rank : 193)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	211	Target Neighborhood Hits	231	Shared Neighborhood Hits	79
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

CSPG3_MOUSE
NC score	0.202118 (rank : 194)	θ value	0.365318 (rank : 119)
Query Neighborhood Hits	211	Target Neighborhood Hits	657	Shared Neighborhood Hits	120
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LRP2_HUMAN
NC score	0.201957 (rank : 195)	θ value	0.0252991 (rank : 78)
Query Neighborhood Hits	211	Target Neighborhood Hits	573	Shared Neighborhood Hits	147
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ITB4_HUMAN
NC score	0.200892 (rank : 196)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	211	Target Neighborhood Hits	458	Shared Neighborhood Hits	111
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

LAMA5_HUMAN
NC score	0.200163 (rank : 197)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	211	Target Neighborhood Hits	976	Shared Neighborhood Hits	129
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

KR102_HUMAN
NC score	0.199617 (rank : 198)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	211	Target Neighborhood Hits	264	Shared Neighborhood Hits	89
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

TSP4_MOUSE
NC score	0.199571 (rank : 199)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	211	Target Neighborhood Hits	276	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

ISK7_MOUSE
NC score	0.199226 (rank : 200)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

MATN2_HUMAN
NC score	0.199106 (rank : 201)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	211	Target Neighborhood Hits	365	Shared Neighborhood Hits	99
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

SUSD1_HUMAN
NC score	0.198900 (rank : 202)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	211	Target Neighborhood Hits	285	Shared Neighborhood Hits	86
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TSP4_HUMAN
NC score	0.197450 (rank : 203)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	211	Target Neighborhood Hits	277	Shared Neighborhood Hits	104
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

MATN2_MOUSE
NC score	0.196850 (rank : 204)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	211	Target Neighborhood Hits	356	Shared Neighborhood Hits	100
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

KRA52_HUMAN
NC score	0.196291 (rank : 205)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	211	Target Neighborhood Hits	236	Shared Neighborhood Hits	80
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

EMR1_HUMAN
NC score	0.195953 (rank : 206)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	211	Target Neighborhood Hits	382	Shared Neighborhood Hits	106
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

CSPG3_HUMAN
NC score	0.194033 (rank : 207)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	211	Target Neighborhood Hits	676	Shared Neighborhood Hits	115
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LAMC2_MOUSE
NC score	0.193919 (rank : 208)	θ value	0.62314 (rank : 129)
Query Neighborhood Hits	211	Target Neighborhood Hits	614	Shared Neighborhood Hits	119
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LDLR_MOUSE
NC score	0.191635 (rank : 209)	θ value	0.0193708 (rank : 73)
Query Neighborhood Hits	211	Target Neighborhood Hits	382	Shared Neighborhood Hits	107
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KR109_HUMAN
NC score	0.188475 (rank : 210)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	211	Target Neighborhood Hits	226	Shared Neighborhood Hits	84
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR105_HUMAN
NC score	0.187984 (rank : 211)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	211	Target Neighborhood Hits	271	Shared Neighborhood Hits	94
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

COMP_MOUSE
NC score	0.187970 (rank : 212)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	211	Target Neighborhood Hits	290	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

LAMA1_HUMAN
NC score	0.187606 (rank : 213)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	211	Target Neighborhood Hits	804	Shared Neighborhood Hits	123
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NTNG2_MOUSE
NC score	0.187446 (rank : 214)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	211	Target Neighborhood Hits	276	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

CSPG2_HUMAN
NC score	0.187345 (rank : 215)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	211	Target Neighborhood Hits	681	Shared Neighborhood Hits	121
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

TENR_MOUSE
NC score	0.187322 (rank : 216)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	211	Target Neighborhood Hits	531	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

CSPG2_MOUSE
NC score	0.187219 (rank : 217)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	211	Target Neighborhood Hits	711	Shared Neighborhood Hits	119
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

NTNG2_HUMAN
NC score	0.187082 (rank : 218)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	211	Target Neighborhood Hits	276	Shared Neighborhood Hits	124
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NRG3_MOUSE
NC score	0.187001 (rank : 219)	θ value	0.365318 (rank : 122)
Query Neighborhood Hits	211	Target Neighborhood Hits	132	Shared Neighborhood Hits	65
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

TENR_HUMAN
NC score	0.186906 (rank : 220)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	211	Target Neighborhood Hits	526	Shared Neighborhood Hits	126
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

LAMB1_MOUSE
NC score	0.186872 (rank : 221)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	211	Target Neighborhood Hits	919	Shared Neighborhood Hits	128
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA1_MOUSE
NC score	0.186695 (rank : 222)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	211	Target Neighborhood Hits	838	Shared Neighborhood Hits	127
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LDLR_HUMAN
NC score	0.186432 (rank : 223)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	211	Target Neighborhood Hits	375	Shared Neighborhood Hits	107
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MFGM_MOUSE
NC score	0.186245 (rank : 224)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	211	Target Neighborhood Hits	233	Shared Neighborhood Hits	106
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

LAMC3_MOUSE
NC score	0.185908 (rank : 225)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	211	Target Neighborhood Hits	624	Shared Neighborhood Hits	121
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

EMR1_MOUSE
NC score	0.185639 (rank : 226)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	211	Target Neighborhood Hits	349	Shared Neighborhood Hits	98
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

VLDLR_HUMAN
NC score	0.184889 (rank : 227)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	211	Target Neighborhood Hits	383	Shared Neighborhood Hits	108
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CRIM1_HUMAN
NC score	0.184774 (rank : 228)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	211	Target Neighborhood Hits	362	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KRA56_HUMAN
NC score	0.184690 (rank : 229)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	211	Target Neighborhood Hits	207	Shared Neighborhood Hits	79
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LAMC3_HUMAN
NC score	0.182759 (rank : 230)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	211	Target Neighborhood Hits	588	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

TICN1_HUMAN
NC score	0.181627 (rank : 231)	θ value	0.62314 (rank : 132)
Query Neighborhood Hits	211	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

VLDLR_MOUSE
NC score	0.179537 (rank : 232)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	211	Target Neighborhood Hits	360	Shared Neighborhood Hits	106
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LAMA2_HUMAN
NC score	0.179390 (rank : 233)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	211	Target Neighborhood Hits	1092	Shared Neighborhood Hits	129
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_MOUSE
NC score	0.179225 (rank : 234)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	211	Target Neighborhood Hits	856	Shared Neighborhood Hits	126
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

COMP_HUMAN
NC score	0.178551 (rank : 235)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	211	Target Neighborhood Hits	258	Shared Neighborhood Hits	96
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TICN1_MOUSE
NC score	0.177725 (rank : 236)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	211	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

LRP8_MOUSE
NC score	0.177239 (rank : 237)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	211	Target Neighborhood Hits	385	Shared Neighborhood Hits	98
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

EMR2_HUMAN
NC score	0.176744 (rank : 238)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	211	Target Neighborhood Hits	345	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

NRG3_HUMAN
NC score	0.176571 (rank : 239)	θ value	1.06291 (rank : 137)
Query Neighborhood Hits	211	Target Neighborhood Hits	119	Shared Neighborhood Hits	63
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

LAMB1_HUMAN
NC score	0.176423 (rank : 240)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	211	Target Neighborhood Hits	1018	Shared Neighborhood Hits	124
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

IPK2_MOUSE
NC score	0.175738 (rank : 241)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	211	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

LAMC2_HUMAN
NC score	0.175608 (rank : 242)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	211	Target Neighborhood Hits	715	Shared Neighborhood Hits	114
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

KR10C_HUMAN
NC score	0.174976 (rank : 243)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	211	Target Neighborhood Hits	219	Shared Neighborhood Hits	88
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

PGBM_HUMAN
NC score	0.174865 (rank : 244)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	211	Target Neighborhood Hits	1113	Shared Neighborhood Hits	150
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TSP3_MOUSE
NC score	0.173952 (rank : 245)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	211	Target Neighborhood Hits	247	Shared Neighborhood Hits	90
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

LAMB3_MOUSE
NC score	0.173536 (rank : 246)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	211	Target Neighborhood Hits	444	Shared Neighborhood Hits	113
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

KR510_HUMAN
NC score	0.173502 (rank : 247)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	211	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

GRN_MOUSE
NC score	0.173468 (rank : 248)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	211	Target Neighborhood Hits	248	Shared Neighborhood Hits	83
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

PGBM_MOUSE
NC score	0.173300 (rank : 249)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	211	Target Neighborhood Hits	1073	Shared Neighborhood Hits	149
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KR108_HUMAN
NC score	0.173202 (rank : 250)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	211	Target Neighborhood Hits	226	Shared Neighborhood Hits	81
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

CD97_HUMAN
NC score	0.172782 (rank : 251)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	211	Target Neighborhood Hits	353	Shared Neighborhood Hits	101
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

KAZD1_HUMAN
NC score	0.172017 (rank : 252)	θ value	0.279714 (rank : 113)
Query Neighborhood Hits	211	Target Neighborhood Hits	248	Shared Neighborhood Hits	47
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

LAMC1_HUMAN
NC score	0.171726 (rank : 253)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	211	Target Neighborhood Hits	922	Shared Neighborhood Hits	126
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

IBP7_MOUSE
NC score	0.170780 (rank : 254)	θ value	0.0148317 (rank : 68)
Query Neighborhood Hits	211	Target Neighborhood Hits	230	Shared Neighborhood Hits	38
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

TSP3_HUMAN
NC score	0.170445 (rank : 255)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	211	Target Neighborhood Hits	250	Shared Neighborhood Hits	88
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

LAMA3_MOUSE
NC score	0.169943 (rank : 256)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	211	Target Neighborhood Hits	859	Shared Neighborhood Hits	133
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

IBP7_HUMAN
NC score	0.169260 (rank : 257)	θ value	0.0431538 (rank : 86)
Query Neighborhood Hits	211	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

RECK_MOUSE
NC score	0.169248 (rank : 258)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	211	Target Neighborhood Hits	158	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

LRP8_HUMAN
NC score	0.168508 (rank : 259)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	211	Target Neighborhood Hits	346	Shared Neighborhood Hits	94
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LAMB3_HUMAN
NC score	0.168074 (rank : 260)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	211	Target Neighborhood Hits	461	Shared Neighborhood Hits	107
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

KR10B_HUMAN
NC score	0.168026 (rank : 261)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	211	Target Neighborhood Hits	269	Shared Neighborhood Hits	88
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LAMA2_MOUSE
NC score	0.167806 (rank : 262)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	211	Target Neighborhood Hits	1198	Shared Neighborhood Hits	126
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

PROZ_HUMAN
NC score	0.167245 (rank : 263)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	211	Target Neighborhood Hits	422	Shared Neighborhood Hits	111
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FATH_HUMAN
NC score	0.165955 (rank : 264)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	211	Target Neighborhood Hits	570	Shared Neighborhood Hits	136
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

GRN_HUMAN
NC score	0.165663 (rank : 265)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	211	Target Neighborhood Hits	268	Shared Neighborhood Hits	78
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

SPRL1_HUMAN
NC score	0.165574 (rank : 266)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	211	Target Neighborhood Hits	231	Shared Neighborhood Hits	38
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

NTNG1_HUMAN
NC score	0.164755 (rank : 267)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	211	Target Neighborhood Hits	247	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
NC score	0.163795 (rank : 268)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	211	Target Neighborhood Hits	246	Shared Neighborhood Hits	102
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PROZ_MOUSE
NC score	0.163479 (rank : 269)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	211	Target Neighborhood Hits	410	Shared Neighborhood Hits	109
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PCSK5_MOUSE
NC score	0.162944 (rank : 270)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	211	Target Neighborhood Hits	613	Shared Neighborhood Hits	116
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

LAMA3_HUMAN
NC score	0.162647 (rank : 271)	θ value	0.0193708 (rank : 72)
Query Neighborhood Hits	211	Target Neighborhood Hits	760	Shared Neighborhood Hits	118
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

RELN_MOUSE
NC score	0.162318 (rank : 272)	θ value	0.279714 (rank : 118)
Query Neighborhood Hits	211	Target Neighborhood Hits	235	Shared Neighborhood Hits	102
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

KAZD1_MOUSE
NC score	0.160689 (rank : 273)	θ value	0.365318 (rank : 121)
Query Neighborhood Hits	211	Target Neighborhood Hits	281	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

TENN_MOUSE
NC score	0.159352 (rank : 274)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	211	Target Neighborhood Hits	484	Shared Neighborhood Hits	117
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

KRA13_HUMAN
NC score	0.159152 (rank : 275)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	211	Target Neighborhood Hits	144	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

USH2A_MOUSE
NC score	0.158637 (rank : 276)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	211	Target Neighborhood Hits	626	Shared Neighborhood Hits	113
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

RELN_HUMAN
NC score	0.157952 (rank : 277)	θ value	0.21417 (rank : 108)
Query Neighborhood Hits	211	Target Neighborhood Hits	233	Shared Neighborhood Hits	99
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

LRP4_HUMAN
NC score	0.157145 (rank : 278)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	211	Target Neighborhood Hits	355	Shared Neighborhood Hits	97
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

CFC1_HUMAN
NC score	0.157110 (rank : 279)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	211	Target Neighborhood Hits	148	Shared Neighborhood Hits	84
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

MATN3_HUMAN
NC score	0.156966 (rank : 280)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	211	Target Neighborhood Hits	268	Shared Neighborhood Hits	83
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
NC score	0.156288 (rank : 281)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	211	Target Neighborhood Hits	261	Shared Neighborhood Hits	83
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

KRA44_HUMAN
NC score	0.156135 (rank : 282)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	211	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

LRP4_MOUSE
NC score	0.156115 (rank : 283)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	211	Target Neighborhood Hits	351	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

HABP2_MOUSE
NC score	0.155758 (rank : 284)	θ value	0.0563607 (rank : 88)
Query Neighborhood Hits	211	Target Neighborhood Hits	445	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

MATN4_HUMAN
NC score	0.154840 (rank : 285)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	211	Target Neighborhood Hits	287	Shared Neighborhood Hits	87
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

USH2A_HUMAN
NC score	0.153641 (rank : 286)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	211	Target Neighborhood Hits	600	Shared Neighborhood Hits	114
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LCE1B_HUMAN
NC score	0.153082 (rank : 287)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	211	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

HABP2_HUMAN
NC score	0.151980 (rank : 288)	θ value	0.365318 (rank : 120)
Query Neighborhood Hits	211	Target Neighborhood Hits	431	Shared Neighborhood Hits	115
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

FRAS1_HUMAN
NC score	0.151951 (rank : 289)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	211	Target Neighborhood Hits	759	Shared Neighborhood Hits	118
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CD248_MOUSE
NC score	0.151138 (rank : 290)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	211	Target Neighborhood Hits	578	Shared Neighborhood Hits	86
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_HUMAN
NC score	0.150472 (rank : 291)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	211	Target Neighborhood Hits	679	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TENN_HUMAN
NC score	0.150471 (rank : 292)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	211	Target Neighborhood Hits	453	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ELTD1_MOUSE
NC score	0.150280 (rank : 293)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	211	Target Neighborhood Hits	288	Shared Neighborhood Hits	86
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ATRN_MOUSE
NC score	0.149722 (rank : 294)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	211	Target Neighborhood Hits	519	Shared Neighborhood Hits	120
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CFC1_MOUSE
NC score	0.149254 (rank : 295)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	211	Target Neighborhood Hits	125	Shared Neighborhood Hits	73
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

HMCN1_HUMAN
NC score	0.148872 (rank : 296)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	211	Target Neighborhood Hits	983	Shared Neighborhood Hits	117
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KRA11_HUMAN
NC score	0.148661 (rank : 297)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	211	Target Neighborhood Hits	155	Shared Neighborhood Hits	60
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

VEGFC_HUMAN
NC score	0.148274 (rank : 298)	θ value	0.00102713 (rank : 43)
Query Neighborhood Hits	211	Target Neighborhood Hits	128	Shared Neighborhood Hits	59
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CD97_MOUSE
NC score	0.148179 (rank : 299)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	211	Target Neighborhood Hits	295	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

KRA47_HUMAN
NC score	0.147764 (rank : 300)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	211	Target Neighborhood Hits	204	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

ZAN_HUMAN
NC score	0.147729 (rank : 301)	θ value	0.0563607 (rank : 91)
Query Neighborhood Hits	211	Target Neighborhood Hits	679	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ATRN_HUMAN
NC score	0.147308 (rank : 302)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	211	Target Neighborhood Hits	525	Shared Neighborhood Hits	119
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

SPRL1_MOUSE
NC score	0.145632 (rank : 303)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	211	Target Neighborhood Hits	403	Shared Neighborhood Hits	37
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

MATN4_MOUSE
NC score	0.145610 (rank : 304)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	211	Target Neighborhood Hits	277	Shared Neighborhood Hits	82
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

SSPO_MOUSE
NC score	0.144229 (rank : 305)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	211	Target Neighborhood Hits	800	Shared Neighborhood Hits	129
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

FRAS1_MOUSE
NC score	0.144171 (rank : 306)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	211	Target Neighborhood Hits	747	Shared Neighborhood Hits	115
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LYAM2_HUMAN
NC score	0.144011 (rank : 307)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	211	Target Neighborhood Hits	394	Shared Neighborhood Hits	124
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KR414_HUMAN
NC score	0.142880 (rank : 308)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	211	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LAMA4_MOUSE
NC score	0.142166 (rank : 309)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	211	Target Neighborhood Hits	584	Shared Neighborhood Hits	100
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KRA94_HUMAN
NC score	0.140298 (rank : 310)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	211	Target Neighborhood Hits	204	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

TDGF1_MOUSE
NC score	0.139556 (rank : 311)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	211	Target Neighborhood Hits	146	Shared Neighborhood Hits	80
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

CELR3_HUMAN
NC score	0.139265 (rank : 312)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	211	Target Neighborhood Hits	680	Shared Neighborhood Hits	124
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

SORL_MOUSE
NC score	0.138999 (rank : 313)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	211	Target Neighborhood Hits	439	Shared Neighborhood Hits	101
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TSP1_MOUSE
NC score	0.138771 (rank : 314)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	211	Target Neighborhood Hits	396	Shared Neighborhood Hits	103
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

KRA45_HUMAN
NC score	0.138677 (rank : 315)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	211	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA93_HUMAN
NC score	0.138473 (rank : 316)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	211	Target Neighborhood Hits	203	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

LYAM2_MOUSE
NC score	0.137947 (rank : 317)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	211	Target Neighborhood Hits	420	Shared Neighborhood Hits	127
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LCE1C_HUMAN
NC score	0.137699 (rank : 318)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	211	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

TSP1_HUMAN
NC score	0.137317 (rank : 319)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	211	Target Neighborhood Hits	389	Shared Neighborhood Hits	103
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

KR103_HUMAN
NC score	0.136647 (rank : 320)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	211	Target Neighborhood Hits	212	Shared Neighborhood Hits	76
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

CELR3_MOUSE
NC score	0.136323 (rank : 321)	θ value	1.06291 (rank : 136)
Query Neighborhood Hits	211	Target Neighborhood Hits	687	Shared Neighborhood Hits	125
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

KRA92_HUMAN
NC score	0.136173 (rank : 322)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	211	Target Neighborhood Hits	198	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LAMA4_HUMAN
NC score	0.135788 (rank : 323)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	211	Target Neighborhood Hits	708	Shared Neighborhood Hits	99
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KRA98_HUMAN
NC score	0.132747 (rank : 324)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	211	Target Neighborhood Hits	185	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

CELR2_HUMAN
NC score	0.131760 (rank : 325)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	211	Target Neighborhood Hits	657	Shared Neighborhood Hits	126
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

KR412_HUMAN
NC score	0.130747 (rank : 326)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	211	Target Neighborhood Hits	178	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

SORL_HUMAN
NC score	0.130020 (rank : 327)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	211	Target Neighborhood Hits	440	Shared Neighborhood Hits	90
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

NFX1_HUMAN
NC score	0.129841 (rank : 328)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	211	Target Neighborhood Hits	405	Shared Neighborhood Hits	73
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

LYAM3_MOUSE
NC score	0.129526 (rank : 329)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	211	Target Neighborhood Hits	390	Shared Neighborhood Hits	106
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LCE1D_HUMAN
NC score	0.129369 (rank : 330)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	211	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

TSP2_HUMAN
NC score	0.127830 (rank : 331)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	211	Target Neighborhood Hits	359	Shared Neighborhood Hits	98
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

CELR1_HUMAN
NC score	0.127180 (rank : 332)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	211	Target Neighborhood Hits	613	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

LYAM1_HUMAN
NC score	0.126900 (rank : 333)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	211	Target Neighborhood Hits	315	Shared Neighborhood Hits	109
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LCE1E_HUMAN
NC score	0.126392 (rank : 334)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	211	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

CELR1_MOUSE
NC score	0.126114 (rank : 335)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	211	Target Neighborhood Hits	617	Shared Neighborhood Hits	129
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

TSP2_MOUSE
NC score	0.125523 (rank : 336)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	211	Target Neighborhood Hits	352	Shared Neighborhood Hits	97
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TDGF1_HUMAN
NC score	0.125516 (rank : 337)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	211	Target Neighborhood Hits	132	Shared Neighborhood Hits	76
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

KRA15_HUMAN
NC score	0.123439 (rank : 338)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	211	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

TDGF2_HUMAN
NC score	0.123085 (rank : 339)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	211	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

CELR2_MOUSE
NC score	0.121848 (rank : 340)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	211	Target Neighborhood Hits	584	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

KR10A_HUMAN
NC score	0.121114 (rank : 341)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	211	Target Neighborhood Hits	232	Shared Neighborhood Hits	74
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

NRX1A_HUMAN
NC score	0.120237 (rank : 342)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	211	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

LYAM1_MOUSE
NC score	0.119910 (rank : 343)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	211	Target Neighborhood Hits	332	Shared Neighborhood Hits	103
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

NRX1A_MOUSE
NC score	0.119800 (rank : 344)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	211	Target Neighborhood Hits	164	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

LCE1A_HUMAN
NC score	0.117529 (rank : 345)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	211	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

KRA99_HUMAN
NC score	0.113021 (rank : 346)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	211	Target Neighborhood Hits	173	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

HTRA1_MOUSE
NC score	0.112763 (rank : 347)	θ value	0.279714 (rank : 110)
Query Neighborhood Hits	211	Target Neighborhood Hits	140	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

HGFA_MOUSE
NC score	0.112690 (rank : 348)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	211	Target Neighborhood Hits	419	Shared Neighborhood Hits	106
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

PGCB_MOUSE
NC score	0.112272 (rank : 349)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	211	Target Neighborhood Hits	459	Shared Neighborhood Hits	91
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

VWF_HUMAN
NC score	0.111557 (rank : 350)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	211	Target Neighborhood Hits	396	Shared Neighborhood Hits	100
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

LYAM3_HUMAN
NC score	0.111288 (rank : 351)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	211	Target Neighborhood Hits	378	Shared Neighborhood Hits	103
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

ELTD1_HUMAN
NC score	0.111271 (rank : 352)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	211	Target Neighborhood Hits	269	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

FAT2_HUMAN
NC score	0.111025 (rank : 353)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	211	Target Neighborhood Hits	507	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

HGFA_HUMAN
NC score	0.109190 (rank : 354)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	211	Target Neighborhood Hits	436	Shared Neighborhood Hits	105
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

NRX3A_HUMAN
NC score	0.109140 (rank : 355)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	211	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

CO6_HUMAN
NC score	0.108670 (rank : 356)	θ value	0.163984 (rank : 102)
Query Neighborhood Hits	211	Target Neighborhood Hits	331	Shared Neighborhood Hits	86
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

NET2_MOUSE
NC score	0.106859 (rank : 357)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	211	Target Neighborhood Hits	193	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

PGCB_HUMAN
NC score	0.106206 (rank : 358)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	211	Target Neighborhood Hits	478	Shared Neighborhood Hits	89
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

NET4_HUMAN
NC score	0.105894 (rank : 359)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	211	Target Neighborhood Hits	191	Shared Neighborhood Hits	78
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NRX2A_HUMAN
NC score	0.104438 (rank : 360)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	211	Target Neighborhood Hits	614	Shared Neighborhood Hits	70
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

HTRA1_HUMAN
NC score	0.104200 (rank : 361)	θ value	0.813845 (rank : 134)
Query Neighborhood Hits	211	Target Neighborhood Hits	155	Shared Neighborhood Hits	45
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

LCE1F_HUMAN
NC score	0.104056 (rank : 362)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	211	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

NET4_MOUSE
NC score	0.103372 (rank : 363)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	211	Target Neighborhood Hits	180	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NET2_HUMAN
NC score	0.102835 (rank : 364)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	211	Target Neighborhood Hits	194	Shared Neighborhood Hits	77
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

MUC5B_HUMAN
NC score	0.102661 (rank : 365)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	211	Target Neighborhood Hits	1020	Shared Neighborhood Hits	108
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

FA10_MOUSE
NC score	0.102053 (rank : 366)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	211	Target Neighborhood Hits	435	Shared Neighborhood Hits	103
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

VWF_MOUSE
NC score	0.100320 (rank : 367)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	211	Target Neighborhood Hits	381	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FA10_HUMAN
NC score	0.100074 (rank : 368)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	211	Target Neighborhood Hits	431	Shared Neighborhood Hits	104
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
NC score	0.099917 (rank : 369)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	211	Target Neighborhood Hits	425	Shared Neighborhood Hits	106
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

PROC_MOUSE
NC score	0.099294 (rank : 370)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	211	Target Neighborhood Hits	426	Shared Neighborhood Hits	111
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

FA9_HUMAN
NC score	0.098547 (rank : 371)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	211	Target Neighborhood Hits	421	Shared Neighborhood Hits	103
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

CNTP4_MOUSE
NC score	0.098466 (rank : 372)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	211	Target Neighborhood Hits	193	Shared Neighborhood Hits	72
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

MMRN1_HUMAN
NC score	0.097677 (rank : 373)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	211	Target Neighborhood Hits	636	Shared Neighborhood Hits	79
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MT4_MOUSE
NC score	0.096919 (rank : 374)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	211	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_MOUSE
NC score	0.096770 (rank : 375)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	211	Target Neighborhood Hits	447	Shared Neighborhood Hits	79
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

CNTP2_HUMAN
NC score	0.094336 (rank : 376)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	211	Target Neighborhood Hits	199	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
NC score	0.093848 (rank : 377)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	211	Target Neighborhood Hits	194	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP4_HUMAN
NC score	0.093256 (rank : 378)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	211	Target Neighborhood Hits	187	Shared Neighborhood Hits	67
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP3_HUMAN
NC score	0.092609 (rank : 379)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	211	Target Neighborhood Hits	195	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

LCE2A_HUMAN
NC score	0.091553 (rank : 380)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	211	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

FA7_HUMAN
NC score	0.090684 (rank : 381)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	211	Target Neighborhood Hits	404	Shared Neighborhood Hits	95
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

KRA42_HUMAN
NC score	0.090347 (rank : 382)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	211	Target Neighborhood Hits	149	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

LRP6_HUMAN
NC score	0.090072 (rank : 383)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	211	Target Neighborhood Hits	235	Shared Neighborhood Hits	61
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MFGM_HUMAN
NC score	0.088899 (rank : 384)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	211	Target Neighborhood Hits	150	Shared Neighborhood Hits	67
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

APR3_MOUSE
NC score	0.088410 (rank : 385)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	211	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

PGH2_MOUSE
NC score	0.087852 (rank : 386)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	211	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

LRP6_MOUSE
NC score	0.087802 (rank : 387)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	211	Target Neighborhood Hits	232	Shared Neighborhood Hits	59
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

SO1B2_MOUSE
NC score	0.087447 (rank : 388)	θ value	0.0736092 (rank : 94)
Query Neighborhood Hits	211	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

VEGFC_MOUSE
NC score	0.087264 (rank : 389)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	211	Target Neighborhood Hits	119	Shared Neighborhood Hits	55
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

KR410_HUMAN
NC score	0.087058 (rank : 390)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	211	Target Neighborhood Hits	156	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

PROC_HUMAN
NC score	0.086272 (rank : 391)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	211	Target Neighborhood Hits	406	Shared Neighborhood Hits	107
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

LRP5_MOUSE
NC score	0.085420 (rank : 392)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	211	Target Neighborhood Hits	236	Shared Neighborhood Hits	63
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

NET1_HUMAN
NC score	0.085343 (rank : 393)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	211	Target Neighborhood Hits	149	Shared Neighborhood Hits	64
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

SO1B3_HUMAN
NC score	0.084883 (rank : 394)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	211	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO1A2_HUMAN
NC score	0.084160 (rank : 395)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	211	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

PGH2_HUMAN
NC score	0.083896 (rank : 396)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	211	Target Neighborhood Hits	103	Shared Neighborhood Hits	56
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

MT4_HUMAN
NC score	0.083724 (rank : 397)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	211	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ESM1_HUMAN
NC score	0.083015 (rank : 398)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	211	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

LRP5_HUMAN
NC score	0.082764 (rank : 399)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	211	Target Neighborhood Hits	224	Shared Neighborhood Hits	56
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

CNTP1_HUMAN
NC score	0.082723 (rank : 400)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	211	Target Neighborhood Hits	196	Shared Neighborhood Hits	64
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

NET1_MOUSE
NC score	0.082695 (rank : 401)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	211	Target Neighborhood Hits	151	Shared Neighborhood Hits	63
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

MEP1A_MOUSE
NC score	0.082478 (rank : 402)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	211	Target Neighborhood Hits	166	Shared Neighborhood Hits	68
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

TIE1_MOUSE
NC score	0.082260 (rank : 403)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	211	Target Neighborhood Hits	1266	Shared Neighborhood Hits	125
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

FA7_MOUSE
NC score	0.081900 (rank : 404)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	211	Target Neighborhood Hits	374	Shared Neighborhood Hits	87
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

SO1A4_MOUSE
NC score	0.081692 (rank : 405)	θ value	0.21417 (rank : 109)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO1B1_HUMAN
NC score	0.081457 (rank : 406)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	211	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

CO7_HUMAN
NC score	0.081385 (rank : 407)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	211	Target Neighborhood Hits	278	Shared Neighborhood Hits	75
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

PGH1_MOUSE
NC score	0.081258 (rank : 408)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	211	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

MEP1A_HUMAN
NC score	0.080803 (rank : 409)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	211	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

PERT_HUMAN
NC score	0.080539 (rank : 410)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	211	Target Neighborhood Hits	221	Shared Neighborhood Hits	61
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MT3_MOUSE
NC score	0.080102 (rank : 411)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	211	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

VASN_HUMAN
NC score	0.079536 (rank : 412)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	211	Target Neighborhood Hits	449	Shared Neighborhood Hits	88
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

TIE1_HUMAN
NC score	0.079430 (rank : 413)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	211	Target Neighborhood Hits	1241	Shared Neighborhood Hits	120
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

PGCA_HUMAN
NC score	0.079087 (rank : 414)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	211	Target Neighborhood Hits	821	Shared Neighborhood Hits	98
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SO1A5_MOUSE
NC score	0.079027 (rank : 415)	θ value	0.62314 (rank : 131)
Query Neighborhood Hits	211	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

UROL1_MOUSE
NC score	0.078694 (rank : 416)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	211	Target Neighborhood Hits	235	Shared Neighborhood Hits	59
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

LORI_MOUSE
NC score	0.078450 (rank : 417)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	211	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LCE3A_HUMAN
NC score	0.078038 (rank : 418)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	211	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

SO4A1_HUMAN
NC score	0.078030 (rank : 419)	θ value	4.03905 (rank : 177)
Query Neighborhood Hits	211	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

SO5A1_HUMAN
NC score	0.077957 (rank : 420)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	211	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

MT3_HUMAN
NC score	0.077800 (rank : 421)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	211	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

SO3A1_MOUSE
NC score	0.077256 (rank : 422)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	211	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO3A1_HUMAN
NC score	0.077065 (rank : 423)	θ value	3.0926 (rank : 164)
Query Neighborhood Hits	211	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

ESM1_MOUSE
NC score	0.076714 (rank : 424)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	211	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

SO1A6_MOUSE
NC score	0.075392 (rank : 425)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	211	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO1C1_MOUSE
NC score	0.074640 (rank : 426)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	211	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1A1_MOUSE
NC score	0.074240 (rank : 427)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	211	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

HG2A_MOUSE
NC score	0.073172 (rank : 428)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	211	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

CO8B_MOUSE
NC score	0.073045 (rank : 429)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	211	Target Neighborhood Hits	224	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADAM8_MOUSE
NC score	0.072965 (rank : 430)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	211	Target Neighborhood Hits	326	Shared Neighborhood Hits	88
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

MUC2_HUMAN
NC score	0.072821 (rank : 431)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	211	Target Neighborhood Hits	906	Shared Neighborhood Hits	88
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PERT_MOUSE
NC score	0.072346 (rank : 432)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	211	Target Neighborhood Hits	221	Shared Neighborhood Hits	56
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SO1C1_HUMAN
NC score	0.072241 (rank : 433)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	211	Target Neighborhood Hits	32	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

CNTP1_MOUSE
NC score	0.072114 (rank : 434)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	211	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

PCSK5_HUMAN
NC score	0.072045 (rank : 435)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	211	Target Neighborhood Hits	291	Shared Neighborhood Hits	87
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

VASN_MOUSE
NC score	0.071984 (rank : 436)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	211	Target Neighborhood Hits	426	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

CORIN_HUMAN
NC score	0.071725 (rank : 437)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	211	Target Neighborhood Hits	453	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

UROL1_HUMAN
NC score	0.071642 (rank : 438)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	211	Target Neighborhood Hits	213	Shared Neighborhood Hits	57
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

APR3_HUMAN
NC score	0.071624 (rank : 439)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	211	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

PGH1_HUMAN
NC score	0.071235 (rank : 440)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	211	Target Neighborhood Hits	91	Shared Neighborhood Hits	49
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

EMR3_HUMAN
NC score	0.071212 (rank : 441)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	211	Target Neighborhood Hits	245	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

TPA_MOUSE
NC score	0.071180 (rank : 442)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	211	Target Neighborhood Hits	335	Shared Neighborhood Hits	90
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

HTRA3_HUMAN
NC score	0.071099 (rank : 443)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	211	Target Neighborhood Hits	152	Shared Neighborhood Hits	41
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

LCE4A_HUMAN
NC score	0.070013 (rank : 444)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	211	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

SO2A1_MOUSE
NC score	0.069991 (rank : 445)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	211	Target Neighborhood Hits	51	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

MEP1B_MOUSE
NC score	0.069579 (rank : 446)	θ value	3.0926 (rank : 163)
Query Neighborhood Hits	211	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MUC13_HUMAN
NC score	0.068499 (rank : 447)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	211	Target Neighborhood Hits	164	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

LCE2C_HUMAN
NC score	0.068214 (rank : 448)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	211	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

ADAM8_HUMAN
NC score	0.068112 (rank : 449)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	211	Target Neighborhood Hits	327	Shared Neighborhood Hits	91
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

NOV_HUMAN
NC score	0.068008 (rank : 450)	θ value	0.0961366 (rank : 97)
Query Neighborhood Hits	211	Target Neighborhood Hits	128	Shared Neighborhood Hits	30
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

HTRA3_MOUSE
NC score	0.067782 (rank : 451)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	211	Target Neighborhood Hits	156	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

SO2A1_HUMAN
NC score	0.067218 (rank : 452)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	211	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO4A1_MOUSE
NC score	0.066863 (rank : 453)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	211	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

CRAC1_MOUSE
NC score	0.066536 (rank : 454)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	211	Target Neighborhood Hits	112	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

TPA_HUMAN
NC score	0.066507 (rank : 455)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	211	Target Neighborhood Hits	324	Shared Neighborhood Hits	86
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TECTA_MOUSE
NC score	0.066378 (rank : 456)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	211	Target Neighborhood Hits	244	Shared Neighborhood Hits	75
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

HG2A_HUMAN
NC score	0.066089 (rank : 457)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	211	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

TIE2_HUMAN
NC score	0.065448 (rank : 458)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	211	Target Neighborhood Hits	1192	Shared Neighborhood Hits	116
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

HTRA4_HUMAN
NC score	0.065173 (rank : 459)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	211	Target Neighborhood Hits	119	Shared Neighborhood Hits	24
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

BMPER_MOUSE
NC score	0.065019 (rank : 460)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	211	Target Neighborhood Hits	194	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

WFDC3_HUMAN
NC score	0.064213 (rank : 461)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	211	Target Neighborhood Hits	138	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

TIE2_MOUSE
NC score	0.064002 (rank : 462)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	211	Target Neighborhood Hits	1204	Shared Neighborhood Hits	116
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

CRAC1_HUMAN
NC score	0.063999 (rank : 463)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	211	Target Neighborhood Hits	111	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CORIN_MOUSE
NC score	0.062868 (rank : 464)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	211	Target Neighborhood Hits	451	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LCE2D_HUMAN
NC score	0.062824 (rank : 465)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	211	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

BMPER_HUMAN
NC score	0.062569 (rank : 466)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	211	Target Neighborhood Hits	175	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CO9_MOUSE
NC score	0.062504 (rank : 467)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	211	Target Neighborhood Hits	153	Shared Neighborhood Hits	48
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

PCSK6_HUMAN
NC score	0.061992 (rank : 468)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	211	Target Neighborhood Hits	298	Shared Neighborhood Hits	73
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

ADA11_HUMAN
NC score	0.061671 (rank : 469)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	211	Target Neighborhood Hits	259	Shared Neighborhood Hits	84
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADAM9_MOUSE
NC score	0.061544 (rank : 470)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	211	Target Neighborhood Hits	325	Shared Neighborhood Hits	93
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA11_MOUSE
NC score	0.061050 (rank : 471)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	211	Target Neighborhood Hits	263	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CLC14_MOUSE
NC score	0.059774 (rank : 472)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	211	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

TECTA_HUMAN
NC score	0.059711 (rank : 473)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	211	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TLL1_MOUSE
NC score	0.059462 (rank : 474)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	211	Target Neighborhood Hits	237	Shared Neighborhood Hits	56
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

LCE3B_HUMAN
NC score	0.059249 (rank : 475)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	211	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

MCSP_MOUSE
NC score	0.059041 (rank : 476)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	211	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

LCE2B_HUMAN
NC score	0.059033 (rank : 477)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	211	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

TLL2_HUMAN
NC score	0.059031 (rank : 478)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	211	Target Neighborhood Hits	241	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

KR413_HUMAN
NC score	0.059012 (rank : 479)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	211	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

IBP3_HUMAN
NC score	0.058322 (rank : 480)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	211	Target Neighborhood Hits	67	Shared Neighborhood Hits	20
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

ADA23_HUMAN
NC score	0.058251 (rank : 481)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	211	Target Neighborhood Hits	235	Shared Neighborhood Hits	87
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CFAI_MOUSE
NC score	0.058042 (rank : 482)	θ value	0.0330416 (rank : 80)
Query Neighborhood Hits	211	Target Neighborhood Hits	290	Shared Neighborhood Hits	52
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CYR61_MOUSE
NC score	0.057711 (rank : 483)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	211	Target Neighborhood Hits	156	Shared Neighborhood Hits	44
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

TLL1_HUMAN
NC score	0.056832 (rank : 484)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	211	Target Neighborhood Hits	236	Shared Neighborhood Hits	55
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

BMP1_MOUSE
NC score	0.056609 (rank : 485)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	211	Target Neighborhood Hits	236	Shared Neighborhood Hits	54
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

GNPTA_HUMAN
NC score	0.056340 (rank : 486)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	211	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

BMP1_HUMAN
NC score	0.056108 (rank : 487)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	211	Target Neighborhood Hits	233	Shared Neighborhood Hits	53
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

SO2B1_MOUSE
NC score	0.055685 (rank : 488)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	211	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

CO9_HUMAN
NC score	0.055350 (rank : 489)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	211	Target Neighborhood Hits	147	Shared Neighborhood Hits	47
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

GNPTA_MOUSE
NC score	0.055133 (rank : 490)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	211	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ADA23_MOUSE
NC score	0.055045 (rank : 491)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	211	Target Neighborhood Hits	245	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

SO2B1_HUMAN
NC score	0.054861 (rank : 492)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	211	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

CTGF_HUMAN
NC score	0.054660 (rank : 493)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	211	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

IBP1_MOUSE
NC score	0.054327 (rank : 494)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	211	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP1_HUMAN
NC score	0.053453 (rank : 495)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	211	Target Neighborhood Hits	67	Shared Neighborhood Hits	22
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

CYR61_HUMAN
NC score	0.053368 (rank : 496)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	211	Target Neighborhood Hits	159	Shared Neighborhood Hits	45
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

ADA15_MOUSE
NC score	0.052935 (rank : 497)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	211	Target Neighborhood Hits	324	Shared Neighborhood Hits	95
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ASTN_MOUSE
NC score	0.052838 (rank : 498)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	211	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ADAM9_HUMAN
NC score	0.052477 (rank : 499)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	211	Target Neighborhood Hits	243	Shared Neighborhood Hits	81
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

CLC14_HUMAN
NC score	0.052355 (rank : 500)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	211	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

TLL2_MOUSE
NC score	0.052085 (rank : 501)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	211	Target Neighborhood Hits	240	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CO8B_HUMAN
NC score	0.052070 (rank : 502)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	211	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

LRP3_HUMAN
NC score	0.051874 (rank : 503)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	211	Target Neighborhood Hits	280	Shared Neighborhood Hits	54
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRC21_MOUSE
NC score	0.051398 (rank : 504)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	211	Target Neighborhood Hits	462	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

ASTN_HUMAN
NC score	0.050904 (rank : 505)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	211	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

LRP10_HUMAN
NC score	0.050524 (rank : 506)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	211	Target Neighborhood Hits	197	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

NOV_MOUSE
NC score	0.047019 (rank : 507)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	211	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

EDAD_HUMAN
NC score	0.042460 (rank : 508)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	211	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWZ3, Q5VYJ7	Gene names	EDARADD
Domain Architecture	No domain graphic available
Description	Ectodysplasin A receptor-associated adapter protein (EDAR-associated death domain protein) (Crinkled homolog).

ADAM7_MOUSE
NC score	0.034623 (rank : 509)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	211	Target Neighborhood Hits	200	Shared Neighborhood Hits	62
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

DSC1_HUMAN
NC score	0.011953 (rank : 510)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	211	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q08554	Gene names	DSC1
Domain Architecture
Description	Desmocollin-1 precursor (Desmosomal glycoprotein 2/3) (DG2/DG3).

ZN208_HUMAN
NC score	-0.006120 (rank : 511)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	211	Target Neighborhood Hits	771	Shared Neighborhood Hits	8
SwissProt Accessions	O43345	Gene names	ZNF208, ZNF91L
Domain Architecture
Description	Zinc finger protein 208.