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Network neighborhood for query Sequence : CYR61_MOUSE

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CYR61_MOUSE
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CYR61_HUMAN
θ value	0 (rank : 1)	NC score	0.996395 (rank : 2)
Query Neighborhood Hits	156	Target Neighborhood Hits	159	Shared Neighborhood Hits	148
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	156	Target Neighborhood Hits	156	Shared Neighborhood Hits	156
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

CTGF_HUMAN
θ value	3.79596e-99 (rank : 3)	NC score	0.957833 (rank : 3)
Query Neighborhood Hits	156	Target Neighborhood Hits	128	Shared Neighborhood Hits	85
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	4.34313e-95 (rank : 4)	NC score	0.956743 (rank : 4)
Query Neighborhood Hits	156	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

NOV_HUMAN
θ value	1.44917e-82 (rank : 5)	NC score	0.945954 (rank : 6)
Query Neighborhood Hits	156	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
θ value	3.0217e-80 (rank : 6)	NC score	0.945891 (rank : 7)
Query Neighborhood Hits	156	Target Neighborhood Hits	130	Shared Neighborhood Hits	90
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

WISP1_MOUSE
θ value	5.51964e-74 (rank : 7)	NC score	0.946402 (rank : 5)
Query Neighborhood Hits	156	Target Neighborhood Hits	123	Shared Neighborhood Hits	92
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP1_HUMAN
θ value	1.96316e-71 (rank : 8)	NC score	0.944334 (rank : 8)
Query Neighborhood Hits	156	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP3_HUMAN
θ value	4.39379e-55 (rank : 9)	NC score	0.933422 (rank : 9)
Query Neighborhood Hits	156	Target Neighborhood Hits	87	Shared Neighborhood Hits	74
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

WISP2_HUMAN
θ value	1.61718e-49 (rank : 10)	NC score	0.931154 (rank : 10)
Query Neighborhood Hits	156	Target Neighborhood Hits	126	Shared Neighborhood Hits	93
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	6.14528e-49 (rank : 11)	NC score	0.918924 (rank : 11)
Query Neighborhood Hits	156	Target Neighborhood Hits	129	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

SLIT2_HUMAN
θ value	8.40245e-06 (rank : 12)	NC score	0.119125 (rank : 67)
Query Neighborhood Hits	156	Target Neighborhood Hits	708	Shared Neighborhood Hits	75
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	8.40245e-06 (rank : 13)	NC score	0.117838 (rank : 72)
Query Neighborhood Hits	156	Target Neighborhood Hits	684	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CRDL2_MOUSE
θ value	1.09739e-05 (rank : 14)	NC score	0.280586 (rank : 18)
Query Neighborhood Hits	156	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

HTRA1_MOUSE
θ value	9.29e-05 (rank : 15)	NC score	0.253766 (rank : 23)
Query Neighborhood Hits	156	Target Neighborhood Hits	140	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

HTRA3_HUMAN
θ value	0.000121331 (rank : 16)	NC score	0.248046 (rank : 24)
Query Neighborhood Hits	156	Target Neighborhood Hits	152	Shared Neighborhood Hits	38
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

CRDL1_MOUSE
θ value	0.00020696 (rank : 17)	NC score	0.269410 (rank : 20)
Query Neighborhood Hits	156	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_HUMAN
θ value	0.000270298 (rank : 18)	NC score	0.265503 (rank : 21)
Query Neighborhood Hits	156	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

HTRA3_MOUSE
θ value	0.000270298 (rank : 19)	NC score	0.246545 (rank : 25)
Query Neighborhood Hits	156	Target Neighborhood Hits	156	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

FRAS1_HUMAN
θ value	0.000461057 (rank : 20)	NC score	0.190706 (rank : 30)
Query Neighborhood Hits	156	Target Neighborhood Hits	759	Shared Neighborhood Hits	114
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

HTRA1_HUMAN
θ value	0.000786445 (rank : 21)	NC score	0.255557 (rank : 22)
Query Neighborhood Hits	156	Target Neighborhood Hits	155	Shared Neighborhood Hits	38
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

NELL2_HUMAN
θ value	0.00102713 (rank : 22)	NC score	0.183715 (rank : 34)
Query Neighborhood Hits	156	Target Neighborhood Hits	449	Shared Neighborhood Hits	83
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

CRIM1_HUMAN
θ value	0.00134147 (rank : 23)	NC score	0.304194 (rank : 14)
Query Neighborhood Hits	156	Target Neighborhood Hits	362	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

HTRA4_HUMAN
θ value	0.00134147 (rank : 24)	NC score	0.276882 (rank : 19)
Query Neighborhood Hits	156	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

NELL1_HUMAN
θ value	0.00134147 (rank : 25)	NC score	0.195382 (rank : 29)
Query Neighborhood Hits	156	Target Neighborhood Hits	451	Shared Neighborhood Hits	83
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

ZAN_MOUSE
θ value	0.00134147 (rank : 26)	NC score	0.183350 (rank : 35)
Query Neighborhood Hits	156	Target Neighborhood Hits	808	Shared Neighborhood Hits	101
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FRAS1_MOUSE
θ value	0.00175202 (rank : 27)	NC score	0.189844 (rank : 31)
Query Neighborhood Hits	156	Target Neighborhood Hits	747	Shared Neighborhood Hits	114
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF6_HUMAN
θ value	0.00228821 (rank : 28)	NC score	0.128962 (rank : 60)
Query Neighborhood Hits	156	Target Neighborhood Hits	671	Shared Neighborhood Hits	102
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

SSPO_MOUSE
θ value	0.00298849 (rank : 29)	NC score	0.208684 (rank : 26)
Query Neighborhood Hits	156	Target Neighborhood Hits	800	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ESM1_MOUSE
θ value	0.00665767 (rank : 30)	NC score	0.375707 (rank : 12)
Query Neighborhood Hits	156	Target Neighborhood Hits	107	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

SREC_HUMAN
θ value	0.00665767 (rank : 31)	NC score	0.134755 (rank : 55)
Query Neighborhood Hits	156	Target Neighborhood Hits	645	Shared Neighborhood Hits	84
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

IBP2_MOUSE
θ value	0.00869519 (rank : 32)	NC score	0.207591 (rank : 27)
Query Neighborhood Hits	156	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

ITB2_MOUSE
θ value	0.00869519 (rank : 33)	NC score	0.073145 (rank : 230)
Query Neighborhood Hits	156	Target Neighborhood Hits	326	Shared Neighborhood Hits	61
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

SLIT1_MOUSE
θ value	0.00869519 (rank : 34)	NC score	0.095951 (rank : 116)
Query Neighborhood Hits	156	Target Neighborhood Hits	715	Shared Neighborhood Hits	70
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT3_MOUSE
θ value	0.00869519 (rank : 35)	NC score	0.095041 (rank : 119)
Query Neighborhood Hits	156	Target Neighborhood Hits	700	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

BMPER_MOUSE
θ value	0.0113563 (rank : 36)	NC score	0.288693 (rank : 16)
Query Neighborhood Hits	156	Target Neighborhood Hits	194	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

SLIT1_HUMAN
θ value	0.0113563 (rank : 37)	NC score	0.098324 (rank : 110)
Query Neighborhood Hits	156	Target Neighborhood Hits	700	Shared Neighborhood Hits	70
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

IBP4_MOUSE
θ value	0.0148317 (rank : 38)	NC score	0.140274 (rank : 50)
Query Neighborhood Hits	156	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

MUC5B_HUMAN
θ value	0.0148317 (rank : 39)	NC score	0.182837 (rank : 36)
Query Neighborhood Hits	156	Target Neighborhood Hits	1020	Shared Neighborhood Hits	92
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NELL2_MOUSE
θ value	0.0148317 (rank : 40)	NC score	0.180132 (rank : 38)
Query Neighborhood Hits	156	Target Neighborhood Hits	436	Shared Neighborhood Hits	83
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

ATS1_MOUSE
θ value	0.0193708 (rank : 41)	NC score	0.124360 (rank : 62)
Query Neighborhood Hits	156	Target Neighborhood Hits	158	Shared Neighborhood Hits	61
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

SLIT3_HUMAN
θ value	0.0193708 (rank : 42)	NC score	0.092177 (rank : 129)
Query Neighborhood Hits	156	Target Neighborhood Hits	682	Shared Neighborhood Hits	64
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SPON1_HUMAN
θ value	0.0193708 (rank : 43)	NC score	0.176002 (rank : 40)
Query Neighborhood Hits	156	Target Neighborhood Hits	117	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	0.0193708 (rank : 44)	NC score	0.174591 (rank : 41)
Query Neighborhood Hits	156	Target Neighborhood Hits	123	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

CO1A1_MOUSE
θ value	0.0252991 (rank : 45)	NC score	0.097751 (rank : 113)
Query Neighborhood Hits	156	Target Neighborhood Hits	457	Shared Neighborhood Hits	39
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

ESM1_HUMAN
θ value	0.0252991 (rank : 46)	NC score	0.344327 (rank : 13)
Query Neighborhood Hits	156	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

VWF_MOUSE
θ value	0.0252991 (rank : 47)	NC score	0.166620 (rank : 43)
Query Neighborhood Hits	156	Target Neighborhood Hits	381	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CRDL2_HUMAN
θ value	0.0431538 (rank : 48)	NC score	0.288781 (rank : 15)
Query Neighborhood Hits	156	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

BMPER_HUMAN
θ value	0.0563607 (rank : 49)	NC score	0.280996 (rank : 17)
Query Neighborhood Hits	156	Target Neighborhood Hits	175	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

IBP7_MOUSE
θ value	0.0563607 (rank : 50)	NC score	0.198856 (rank : 28)
Query Neighborhood Hits	156	Target Neighborhood Hits	230	Shared Neighborhood Hits	37
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

IBP4_HUMAN
θ value	0.0736092 (rank : 51)	NC score	0.133643 (rank : 56)
Query Neighborhood Hits	156	Target Neighborhood Hits	52	Shared Neighborhood Hits	22
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

LAMA2_HUMAN
θ value	0.0736092 (rank : 52)	NC score	0.077488 (rank : 208)
Query Neighborhood Hits	156	Target Neighborhood Hits	1092	Shared Neighborhood Hits	67
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ZAN_HUMAN
θ value	0.0736092 (rank : 53)	NC score	0.139469 (rank : 52)
Query Neighborhood Hits	156	Target Neighborhood Hits	679	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CO6_HUMAN
θ value	0.0961366 (rank : 54)	NC score	0.088447 (rank : 156)
Query Neighborhood Hits	156	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

FBLN1_HUMAN
θ value	0.0961366 (rank : 55)	NC score	0.083594 (rank : 177)
Query Neighborhood Hits	156	Target Neighborhood Hits	324	Shared Neighborhood Hits	55
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

IBP2_HUMAN
θ value	0.0961366 (rank : 56)	NC score	0.189007 (rank : 32)
Query Neighborhood Hits	156	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP7_HUMAN
θ value	0.0961366 (rank : 57)	NC score	0.184157 (rank : 33)
Query Neighborhood Hits	156	Target Neighborhood Hits	220	Shared Neighborhood Hits	33
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

SOSD1_HUMAN
θ value	0.0961366 (rank : 58)	NC score	0.090631 (rank : 134)
Query Neighborhood Hits	156	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q6X4U4, Q96HJ7, Q9Y3U3	Gene names	SOSTDC1, USAG1
Domain Architecture	No domain graphic available
Description	Sclerostin domain-containing protein 1 precursor (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1).

KRA58_HUMAN
θ value	0.125558 (rank : 59)	NC score	0.120785 (rank : 64)
Query Neighborhood Hits	156	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ATS1_HUMAN
θ value	0.163984 (rank : 60)	NC score	0.114401 (rank : 75)
Query Neighborhood Hits	156	Target Neighborhood Hits	159	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

NOTC4_HUMAN
θ value	0.163984 (rank : 61)	NC score	0.098757 (rank : 104)
Query Neighborhood Hits	156	Target Neighborhood Hits	905	Shared Neighborhood Hits	82
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	0.163984 (rank : 62)	NC score	0.098429 (rank : 108)
Query Neighborhood Hits	156	Target Neighborhood Hits	872	Shared Neighborhood Hits	84
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SOSD1_MOUSE
θ value	0.163984 (rank : 63)	NC score	0.088549 (rank : 154)
Query Neighborhood Hits	156	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN4, Q8CF09	Gene names	Sostdc1, Sostl, Usag1
Domain Architecture	No domain graphic available
Description	Sclerostin domain-containing protein 1 precursor (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1) (Sclerostin-like protein).

ATS19_MOUSE
θ value	0.21417 (rank : 64)	NC score	0.118812 (rank : 69)
Query Neighborhood Hits	156	Target Neighborhood Hits	188	Shared Neighborhood Hits	60
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

SEM5A_HUMAN
θ value	0.21417 (rank : 65)	NC score	0.088878 (rank : 151)
Query Neighborhood Hits	156	Target Neighborhood Hits	177	Shared Neighborhood Hits	58
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_MOUSE
θ value	0.21417 (rank : 66)	NC score	0.079094 (rank : 197)
Query Neighborhood Hits	156	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

TSP1_MOUSE
θ value	0.21417 (rank : 67)	NC score	0.179262 (rank : 39)
Query Neighborhood Hits	156	Target Neighborhood Hits	396	Shared Neighborhood Hits	112
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADA32_HUMAN
θ value	0.279714 (rank : 68)	NC score	0.045582 (rank : 371)
Query Neighborhood Hits	156	Target Neighborhood Hits	216	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

KAZD1_MOUSE
θ value	0.279714 (rank : 69)	NC score	0.147867 (rank : 49)
Query Neighborhood Hits	156	Target Neighborhood Hits	281	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

NOTC1_MOUSE
θ value	0.279714 (rank : 70)	NC score	0.098444 (rank : 107)
Query Neighborhood Hits	156	Target Neighborhood Hits	916	Shared Neighborhood Hits	79
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ATS20_MOUSE
θ value	0.365318 (rank : 71)	NC score	0.118650 (rank : 70)
Query Neighborhood Hits	156	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

FBN1_HUMAN
θ value	0.365318 (rank : 72)	NC score	0.092317 (rank : 127)
Query Neighborhood Hits	156	Target Neighborhood Hits	557	Shared Neighborhood Hits	77
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

STAB2_HUMAN
θ value	0.365318 (rank : 73)	NC score	0.101537 (rank : 98)
Query Neighborhood Hits	156	Target Neighborhood Hits	534	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ATS12_HUMAN
θ value	0.47712 (rank : 74)	NC score	0.120220 (rank : 65)
Query Neighborhood Hits	156	Target Neighborhood Hits	251	Shared Neighborhood Hits	63
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

KAZD1_HUMAN
θ value	0.47712 (rank : 75)	NC score	0.152976 (rank : 48)
Query Neighborhood Hits	156	Target Neighborhood Hits	248	Shared Neighborhood Hits	39
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

LAMB1_MOUSE
θ value	0.47712 (rank : 76)	NC score	0.075483 (rank : 219)
Query Neighborhood Hits	156	Target Neighborhood Hits	919	Shared Neighborhood Hits	65
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

ATS17_HUMAN
θ value	0.62314 (rank : 77)	NC score	0.111118 (rank : 80)
Query Neighborhood Hits	156	Target Neighborhood Hits	194	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

CFC1_HUMAN
θ value	0.62314 (rank : 78)	NC score	0.084515 (rank : 172)
Query Neighborhood Hits	156	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CO3A1_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.050392 (rank : 366)
Query Neighborhood Hits	156	Target Neighborhood Hits	466	Shared Neighborhood Hits	31
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MCSP_MOUSE
θ value	0.62314 (rank : 80)	NC score	0.115358 (rank : 74)
Query Neighborhood Hits	156	Target Neighborhood Hits	108	Shared Neighborhood Hits	26
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

TSP1_HUMAN
θ value	0.62314 (rank : 81)	NC score	0.181986 (rank : 37)
Query Neighborhood Hits	156	Target Neighborhood Hits	389	Shared Neighborhood Hits	110
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADA23_MOUSE
θ value	0.813845 (rank : 82)	NC score	0.054312 (rank : 345)
Query Neighborhood Hits	156	Target Neighborhood Hits	245	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ATL2_HUMAN
θ value	0.813845 (rank : 83)	NC score	0.139121 (rank : 53)
Query Neighborhood Hits	156	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	0.813845 (rank : 84)	NC score	0.137109 (rank : 54)
Query Neighborhood Hits	156	Target Neighborhood Hits	137	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATS16_HUMAN
θ value	0.813845 (rank : 85)	NC score	0.106219 (rank : 87)
Query Neighborhood Hits	156	Target Neighborhood Hits	208	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS2_MOUSE
θ value	0.813845 (rank : 86)	NC score	0.098836 (rank : 103)
Query Neighborhood Hits	156	Target Neighborhood Hits	179	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

IBP3_MOUSE
θ value	0.813845 (rank : 87)	NC score	0.127605 (rank : 61)
Query Neighborhood Hits	156	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

LAMA2_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.070521 (rank : 240)
Query Neighborhood Hits	156	Target Neighborhood Hits	1198	Shared Neighborhood Hits	70
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.069834 (rank : 244)
Query Neighborhood Hits	156	Target Neighborhood Hits	922	Shared Neighborhood Hits	70
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ATS19_HUMAN
θ value	1.06291 (rank : 90)	NC score	0.117879 (rank : 71)
Query Neighborhood Hits	156	Target Neighborhood Hits	203	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

CO5A2_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.056544 (rank : 331)
Query Neighborhood Hits	156	Target Neighborhood Hits	760	Shared Neighborhood Hits	43
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

HMCN1_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.092122 (rank : 130)
Query Neighborhood Hits	156	Target Neighborhood Hits	983	Shared Neighborhood Hits	106
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

STAB1_HUMAN
θ value	1.06291 (rank : 93)	NC score	0.099634 (rank : 100)
Query Neighborhood Hits	156	Target Neighborhood Hits	546	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.098888 (rank : 102)
Query Neighborhood Hits	156	Target Neighborhood Hits	528	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

ATS12_MOUSE
θ value	1.38821 (rank : 95)	NC score	0.114109 (rank : 76)
Query Neighborhood Hits	156	Target Neighborhood Hits	220	Shared Neighborhood Hits	63
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

FBN1_MOUSE
θ value	1.38821 (rank : 96)	NC score	0.089313 (rank : 147)
Query Neighborhood Hits	156	Target Neighborhood Hits	563	Shared Neighborhood Hits	76
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

IBP5_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.162361 (rank : 45)
Query Neighborhood Hits	156	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
θ value	1.38821 (rank : 98)	NC score	0.164232 (rank : 44)
Query Neighborhood Hits	156	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

LAMB3_MOUSE
θ value	1.38821 (rank : 99)	NC score	0.076083 (rank : 216)
Query Neighborhood Hits	156	Target Neighborhood Hits	444	Shared Neighborhood Hits	61
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

NOTC2_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.092730 (rank : 124)
Query Neighborhood Hits	156	Target Neighborhood Hits	1113	Shared Neighborhood Hits	80
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SEM5B_HUMAN
θ value	1.38821 (rank : 101)	NC score	0.074048 (rank : 225)
Query Neighborhood Hits	156	Target Neighborhood Hits	178	Shared Neighborhood Hits	63
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ADA17_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.054113 (rank : 347)
Query Neighborhood Hits	156	Target Neighborhood Hits	223	Shared Neighborhood Hits	58
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ATL5_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.099601 (rank : 101)
Query Neighborhood Hits	156	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATS20_HUMAN
θ value	1.81305 (rank : 104)	NC score	0.107413 (rank : 84)
Query Neighborhood Hits	156	Target Neighborhood Hits	192	Shared Neighborhood Hits	65
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS9_HUMAN
θ value	1.81305 (rank : 105)	NC score	0.119372 (rank : 66)
Query Neighborhood Hits	156	Target Neighborhood Hits	219	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

CI094_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.090687 (rank : 133)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

LAMA3_MOUSE
θ value	1.81305 (rank : 107)	NC score	0.066332 (rank : 269)
Query Neighborhood Hits	156	Target Neighborhood Hits	859	Shared Neighborhood Hits	77
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

SEM5A_MOUSE
θ value	1.81305 (rank : 108)	NC score	0.085388 (rank : 167)
Query Neighborhood Hits	156	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

TNR9_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.049428 (rank : 369)
Query Neighborhood Hits	156	Target Neighborhood Hits	166	Shared Neighborhood Hits	30
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

VWF_HUMAN
θ value	1.81305 (rank : 110)	NC score	0.166778 (rank : 42)
Query Neighborhood Hits	156	Target Neighborhood Hits	396	Shared Neighborhood Hits	87
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ADA23_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.051578 (rank : 358)
Query Neighborhood Hits	156	Target Neighborhood Hits	235	Shared Neighborhood Hits	69
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADAM2_MOUSE
θ value	2.36792 (rank : 112)	NC score	0.040899 (rank : 373)
Query Neighborhood Hits	156	Target Neighborhood Hits	209	Shared Neighborhood Hits	58
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ATS15_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.105314 (rank : 90)
Query Neighborhood Hits	156	Target Neighborhood Hits	151	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS18_HUMAN
θ value	2.36792 (rank : 114)	NC score	0.104206 (rank : 94)
Query Neighborhood Hits	156	Target Neighborhood Hits	169	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

BAI3_HUMAN
θ value	2.36792 (rank : 115)	NC score	0.078870 (rank : 199)
Query Neighborhood Hits	156	Target Neighborhood Hits	246	Shared Neighborhood Hits	53
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	2.36792 (rank : 116)	NC score	0.082749 (rank : 183)
Query Neighborhood Hits	156	Target Neighborhood Hits	250	Shared Neighborhood Hits	56
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

LAMB1_HUMAN
θ value	2.36792 (rank : 117)	NC score	0.068997 (rank : 250)
Query Neighborhood Hits	156	Target Neighborhood Hits	1018	Shared Neighborhood Hits	62
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LTBP2_MOUSE
θ value	2.36792 (rank : 118)	NC score	0.083893 (rank : 175)
Query Neighborhood Hits	156	Target Neighborhood Hits	617	Shared Neighborhood Hits	72
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

VEGFC_HUMAN
θ value	2.36792 (rank : 119)	NC score	0.055565 (rank : 336)
Query Neighborhood Hits	156	Target Neighborhood Hits	128	Shared Neighborhood Hits	39
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ZNF77_HUMAN
θ value	2.36792 (rank : 120)	NC score	-0.001777 (rank : 380)
Query Neighborhood Hits	156	Target Neighborhood Hits	759	Shared Neighborhood Hits	10
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).

ADA17_MOUSE
θ value	3.0926 (rank : 121)	NC score	0.050369 (rank : 367)
Query Neighborhood Hits	156	Target Neighborhood Hits	201	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ATS18_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.106610 (rank : 86)
Query Neighborhood Hits	156	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS3_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.104179 (rank : 95)
Query Neighborhood Hits	156	Target Neighborhood Hits	179	Shared Neighborhood Hits	62
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

BAI1_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.087317 (rank : 158)
Query Neighborhood Hits	156	Target Neighborhood Hits	340	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

TIF1G_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.012333 (rank : 374)
Query Neighborhood Hits	156	Target Neighborhood Hits	410	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

ATL3_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.108840 (rank : 81)
Query Neighborhood Hits	156	Target Neighborhood Hits	414	Shared Neighborhood Hits	67
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS5_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.081091 (rank : 192)
Query Neighborhood Hits	156	Target Neighborhood Hits	147	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

LAMA3_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.059849 (rank : 309)
Query Neighborhood Hits	156	Target Neighborhood Hits	760	Shared Neighborhood Hits	53
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

STAB1_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.098374 (rank : 109)
Query Neighborhood Hits	156	Target Neighborhood Hits	566	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

VEGFC_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.043275 (rank : 372)
Query Neighborhood Hits	156	Target Neighborhood Hits	119	Shared Neighborhood Hits	35
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CO3A1_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.050001 (rank : 368)
Query Neighborhood Hits	156	Target Neighborhood Hits	452	Shared Neighborhood Hits	33
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

IBP3_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.139946 (rank : 51)
Query Neighborhood Hits	156	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

NDP_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.046912 (rank : 370)
Query Neighborhood Hits	156	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q00604	Gene names	NDP
Domain Architecture
Description	Norrin precursor (Norrie disease protein).

NDP_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.051125 (rank : 363)
Query Neighborhood Hits	156	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P48744	Gene names	Ndp, Ndph
Domain Architecture
Description	Norrin precursor (Norrie disease protein homolog).

NOTC3_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.097766 (rank : 112)
Query Neighborhood Hits	156	Target Neighborhood Hits	1062	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PROS_MOUSE
θ value	5.27518 (rank : 136)	NC score	0.068516 (rank : 254)
Query Neighborhood Hits	156	Target Neighborhood Hits	330	Shared Neighborhood Hits	53
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SREC2_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.097899 (rank : 111)
Query Neighborhood Hits	156	Target Neighborhood Hits	645	Shared Neighborhood Hits	74
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TIF1G_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.010899 (rank : 375)
Query Neighborhood Hits	156	Target Neighborhood Hits	498	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ZN491_HUMAN
θ value	5.27518 (rank : 139)	NC score	-0.004071 (rank : 381)
Query Neighborhood Hits	156	Target Neighborhood Hits	734	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N8L2, Q8NAT8	Gene names	ZNF491
Domain Architecture	No domain graphic available
Description	Zinc finger protein 491.

ATS16_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.105256 (rank : 91)
Query Neighborhood Hits	156	Target Neighborhood Hits	179	Shared Neighborhood Hits	61
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

BAI2_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.081328 (rank : 191)
Query Neighborhood Hits	156	Target Neighborhood Hits	332	Shared Neighborhood Hits	54
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.082559 (rank : 186)
Query Neighborhood Hits	156	Target Neighborhood Hits	323	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CO4A_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.008530 (rank : 376)
Query Neighborhood Hits	156	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

CO4B_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.008525 (rank : 377)
Query Neighborhood Hits	156	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

KRA59_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.121305 (rank : 63)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	59
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMC1_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.067573 (rank : 258)
Query Neighborhood Hits	156	Target Neighborhood Hits	856	Shared Neighborhood Hits	67
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LTB1L_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.075776 (rank : 218)
Query Neighborhood Hits	156	Target Neighborhood Hits	514	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.075931 (rank : 217)
Query Neighborhood Hits	156	Target Neighborhood Hits	479	Shared Neighborhood Hits	70
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NOTC1_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.092288 (rank : 128)
Query Neighborhood Hits	156	Target Neighborhood Hits	906	Shared Neighborhood Hits	84
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

RECQ5_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.004915 (rank : 379)
Query Neighborhood Hits	156	Target Neighborhood Hits	390	Shared Neighborhood Hits	5
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

ANK3_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.005362 (rank : 378)
Query Neighborhood Hits	156	Target Neighborhood Hits	853	Shared Neighborhood Hits	13
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ATS14_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.100390 (rank : 99)
Query Neighborhood Hits	156	Target Neighborhood Hits	382	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

IBP1_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.132917 (rank : 57)
Query Neighborhood Hits	156	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

ITB1_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.058212 (rank : 321)
Query Neighborhood Hits	156	Target Neighborhood Hits	283	Shared Neighborhood Hits	63
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

TENX_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.079234 (rank : 195)
Query Neighborhood Hits	156	Target Neighborhood Hits	789	Shared Neighborhood Hits	93
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TSP2_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.154004 (rank : 46)
Query Neighborhood Hits	156	Target Neighborhood Hits	359	Shared Neighborhood Hits	106
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADAM8_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.050662 (rank : 364)
Query Neighborhood Hits	156	Target Neighborhood Hits	326	Shared Neighborhood Hits	65
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.051444 (rank : 359)
Query Neighborhood Hits	156	Target Neighborhood Hits	325	Shared Neighborhood Hits	73
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

AGRIN_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.107157 (rank : 85)
Query Neighborhood Hits	156	Target Neighborhood Hits	582	Shared Neighborhood Hits	82
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ATL1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.098626 (rank : 106)
Query Neighborhood Hits	156	Target Neighborhood Hits	93	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.077132 (rank : 209)
Query Neighborhood Hits	156	Target Neighborhood Hits	80	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATS13_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.090850 (rank : 132)
Query Neighborhood Hits	156	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.088746 (rank : 152)
Query Neighborhood Hits	156	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS2_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.090105 (rank : 140)
Query Neighborhood Hits	156	Target Neighborhood Hits	179	Shared Neighborhood Hits	56
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS4_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.077078 (rank : 210)
Query Neighborhood Hits	156	Target Neighborhood Hits	138	Shared Neighborhood Hits	48
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.078601 (rank : 200)
Query Neighborhood Hits	156	Target Neighborhood Hits	145	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS5_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.076778 (rank : 212)
Query Neighborhood Hits	156	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS6_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.090161 (rank : 139)
Query Neighborhood Hits	156	Target Neighborhood Hits	141	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS7_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.094755 (rank : 120)
Query Neighborhood Hits	156	Target Neighborhood Hits	169	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS8_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.082431 (rank : 187)
Query Neighborhood Hits	156	Target Neighborhood Hits	145	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS8_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.082319 (rank : 188)
Query Neighborhood Hits	156	Target Neighborhood Hits	139	Shared Neighborhood Hits	51
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

BAI1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.083905 (rank : 174)
Query Neighborhood Hits	156	Target Neighborhood Hits	375	Shared Neighborhood Hits	57
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

C1QR1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.069670 (rank : 246)
Query Neighborhood Hits	156	Target Neighborhood Hits	493	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.069079 (rank : 249)
Query Neighborhood Hits	156	Target Neighborhood Hits	342	Shared Neighborhood Hits	50
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD97_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.056402 (rank : 332)
Query Neighborhood Hits	156	Target Neighborhood Hits	353	Shared Neighborhood Hits	50
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CHRD_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.111564 (rank : 78)
Query Neighborhood Hits	156	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.104349 (rank : 93)
Query Neighborhood Hits	156	Target Neighborhood Hits	102	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CO1A1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.055496 (rank : 337)
Query Neighborhood Hits	156	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO2A1_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.058842 (rank : 318)
Query Neighborhood Hits	156	Target Neighborhood Hits	483	Shared Neighborhood Hits	30
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO7_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.051272 (rank : 361)
Query Neighborhood Hits	156	Target Neighborhood Hits	278	Shared Neighborhood Hits	57
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8B_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.053078 (rank : 354)
Query Neighborhood Hits	156	Target Neighborhood Hits	224	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

COMP_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.065254 (rank : 274)
Query Neighborhood Hits	156	Target Neighborhood Hits	258	Shared Neighborhood Hits	53
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.067459 (rank : 260)
Query Neighborhood Hits	156	Target Neighborhood Hits	290	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.081780 (rank : 190)
Query Neighborhood Hits	156	Target Neighborhood Hits	441	Shared Neighborhood Hits	61
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.078924 (rank : 198)
Query Neighborhood Hits	156	Target Neighborhood Hits	524	Shared Neighborhood Hits	61
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRUM1_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.083327 (rank : 180)
Query Neighborhood Hits	156	Target Neighborhood Hits	457	Shared Neighborhood Hits	67
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.083428 (rank : 179)
Query Neighborhood Hits	156	Target Neighborhood Hits	444	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.082736 (rank : 184)
Query Neighborhood Hits	156	Target Neighborhood Hits	453	Shared Neighborhood Hits	57
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CUBN_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.064665 (rank : 281)
Query Neighborhood Hits	156	Target Neighborhood Hits	482	Shared Neighborhood Hits	63
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.066538 (rank : 267)
Query Neighborhood Hits	156	Target Neighborhood Hits	477	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DLK_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.084603 (rank : 171)
Query Neighborhood Hits	156	Target Neighborhood Hits	401	Shared Neighborhood Hits	64
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.097595 (rank : 114)
Query Neighborhood Hits	156	Target Neighborhood Hits	374	Shared Neighborhood Hits	67
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.082883 (rank : 182)
Query Neighborhood Hits	156	Target Neighborhood Hits	455	Shared Neighborhood Hits	64
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.086268 (rank : 163)
Query Neighborhood Hits	156	Target Neighborhood Hits	456	Shared Neighborhood Hits	68
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.089554 (rank : 144)
Query Neighborhood Hits	156	Target Neighborhood Hits	419	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.086723 (rank : 161)
Query Neighborhood Hits	156	Target Neighborhood Hits	399	Shared Neighborhood Hits	62
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.085621 (rank : 166)
Query Neighborhood Hits	156	Target Neighborhood Hits	435	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.088523 (rank : 155)
Query Neighborhood Hits	156	Target Neighborhood Hits	440	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.089142 (rank : 148)
Query Neighborhood Hits	156	Target Neighborhood Hits	460	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.087042 (rank : 159)
Query Neighborhood Hits	156	Target Neighborhood Hits	413	Shared Neighborhood Hits	61
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.057141 (rank : 327)
Query Neighborhood Hits	156	Target Neighborhood Hits	292	Shared Neighborhood Hits	44
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.060657 (rank : 304)
Query Neighborhood Hits	156	Target Neighborhood Hits	317	Shared Neighborhood Hits	47
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.063296 (rank : 288)
Query Neighborhood Hits	156	Target Neighborhood Hits	325	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.060828 (rank : 303)
Query Neighborhood Hits	156	Target Neighborhood Hits	287	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.061175 (rank : 300)
Query Neighborhood Hits	156	Target Neighborhood Hits	270	Shared Neighborhood Hits	39
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.059348 (rank : 313)
Query Neighborhood Hits	156	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.083188 (rank : 181)
Query Neighborhood Hits	156	Target Neighborhood Hits	365	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.093663 (rank : 123)
Query Neighborhood Hits	156	Target Neighborhood Hits	379	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.062141 (rank : 295)
Query Neighborhood Hits	156	Target Neighborhood Hits	343	Shared Neighborhood Hits	59
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.060622 (rank : 305)
Query Neighborhood Hits	156	Target Neighborhood Hits	358	Shared Neighborhood Hits	53
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EMR1_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.063373 (rank : 286)
Query Neighborhood Hits	156	Target Neighborhood Hits	382	Shared Neighborhood Hits	55
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.059226 (rank : 315)
Query Neighborhood Hits	156	Target Neighborhood Hits	349	Shared Neighborhood Hits	56
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.057100 (rank : 328)
Query Neighborhood Hits	156	Target Neighborhood Hits	345	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FBLN1_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.074148 (rank : 224)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	54
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.075276 (rank : 220)
Query Neighborhood Hits	156	Target Neighborhood Hits	392	Shared Neighborhood Hits	61
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.074256 (rank : 223)
Query Neighborhood Hits	156	Target Neighborhood Hits	505	Shared Neighborhood Hits	65
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.063606 (rank : 284)
Query Neighborhood Hits	156	Target Neighborhood Hits	293	Shared Neighborhood Hits	48
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.062166 (rank : 294)
Query Neighborhood Hits	156	Target Neighborhood Hits	279	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.066107 (rank : 271)
Query Neighborhood Hits	156	Target Neighborhood Hits	278	Shared Neighborhood Hits	45
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.066521 (rank : 268)
Query Neighborhood Hits	156	Target Neighborhood Hits	270	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.068612 (rank : 253)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.068080 (rank : 257)
Query Neighborhood Hits	156	Target Neighborhood Hits	317	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN2_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.090305 (rank : 137)
Query Neighborhood Hits	156	Target Neighborhood Hits	560	Shared Neighborhood Hits	81
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.088970 (rank : 150)
Query Neighborhood Hits	156	Target Neighborhood Hits	549	Shared Neighborhood Hits	79
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.089496 (rank : 146)
Query Neighborhood Hits	156	Target Neighborhood Hits	543	Shared Neighborhood Hits	77
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.061817 (rank : 296)
Query Neighborhood Hits	156	Target Neighborhood Hits	348	Shared Neighborhood Hits	53
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.064024 (rank : 283)
Query Neighborhood Hits	156	Target Neighborhood Hits	343	Shared Neighborhood Hits	53
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GRN_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.085696 (rank : 164)
Query Neighborhood Hits	156	Target Neighborhood Hits	268	Shared Neighborhood Hits	53
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.108227 (rank : 82)
Query Neighborhood Hits	156	Target Neighborhood Hits	248	Shared Neighborhood Hits	55
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HHIP_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.059035 (rank : 317)
Query Neighborhood Hits	156	Target Neighborhood Hits	249	Shared Neighborhood Hits	49
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.056592 (rank : 330)
Query Neighborhood Hits	156	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HTRA2_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.089940 (rank : 141)
Query Neighborhood Hits	156	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.090206 (rank : 138)
Query Neighborhood Hits	156	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

IBP1_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.129947 (rank : 59)
Query Neighborhood Hits	156	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP6_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.051709 (rank : 357)
Query Neighborhood Hits	156	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.053913 (rank : 350)
Query Neighborhood Hits	156	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

ITB1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.061515 (rank : 297)
Query Neighborhood Hits	156	Target Neighborhood Hits	298	Shared Neighborhood Hits	61
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.057519 (rank : 325)
Query Neighborhood Hits	156	Target Neighborhood Hits	282	Shared Neighborhood Hits	49
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.054343 (rank : 344)
Query Neighborhood Hits	156	Target Neighborhood Hits	325	Shared Neighborhood Hits	62
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.055255 (rank : 340)
Query Neighborhood Hits	156	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.054657 (rank : 343)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	63
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.057351 (rank : 326)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	61
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.054233 (rank : 346)
Query Neighborhood Hits	156	Target Neighborhood Hits	318	Shared Neighborhood Hits	62
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.055870 (rank : 334)
Query Neighborhood Hits	156	Target Neighborhood Hits	341	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.063482 (rank : 285)
Query Neighborhood Hits	156	Target Neighborhood Hits	290	Shared Neighborhood Hits	58
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.057587 (rank : 324)
Query Neighborhood Hits	156	Target Neighborhood Hits	277	Shared Neighborhood Hits	54
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

JAG1_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.105459 (rank : 89)
Query Neighborhood Hits	156	Target Neighborhood Hits	514	Shared Neighborhood Hits	77
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.104544 (rank : 92)
Query Neighborhood Hits	156	Target Neighborhood Hits	518	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.095311 (rank : 118)
Query Neighborhood Hits	156	Target Neighborhood Hits	491	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.093834 (rank : 122)
Query Neighborhood Hits	156	Target Neighborhood Hits	504	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR101_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.095937 (rank : 117)
Query Neighborhood Hits	156	Target Neighborhood Hits	261	Shared Neighborhood Hits	63
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.078527 (rank : 202)
Query Neighborhood Hits	156	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.067495 (rank : 259)
Query Neighborhood Hits	156	Target Neighborhood Hits	212	Shared Neighborhood Hits	48
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR104_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.131458 (rank : 58)
Query Neighborhood Hits	156	Target Neighborhood Hits	313	Shared Neighborhood Hits	71
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.084628 (rank : 170)
Query Neighborhood Hits	156	Target Neighborhood Hits	271	Shared Neighborhood Hits	62
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.105820 (rank : 88)
Query Neighborhood Hits	156	Target Neighborhood Hits	347	Shared Neighborhood Hits	77
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.116985 (rank : 73)
Query Neighborhood Hits	156	Target Neighborhood Hits	330	Shared Neighborhood Hits	71
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.092435 (rank : 125)
Query Neighborhood Hits	156	Target Neighborhood Hits	226	Shared Neighborhood Hits	54
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.086692 (rank : 162)
Query Neighborhood Hits	156	Target Neighborhood Hits	226	Shared Neighborhood Hits	54
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.064680 (rank : 279)
Query Neighborhood Hits	156	Target Neighborhood Hits	232	Shared Neighborhood Hits	57
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.077665 (rank : 207)
Query Neighborhood Hits	156	Target Neighborhood Hits	269	Shared Neighborhood Hits	57
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.084347 (rank : 173)
Query Neighborhood Hits	156	Target Neighborhood Hits	219	Shared Neighborhood Hits	55
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.072676 (rank : 232)
Query Neighborhood Hits	156	Target Neighborhood Hits	144	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.054080 (rank : 348)
Query Neighborhood Hits	156	Target Neighborhood Hits	156	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.070577 (rank : 239)
Query Neighborhood Hits	156	Target Neighborhood Hits	178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.065020 (rank : 277)
Query Neighborhood Hits	156	Target Neighborhood Hits	199	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.078018 (rank : 205)
Query Neighborhood Hits	156	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.079214 (rank : 196)
Query Neighborhood Hits	156	Target Neighborhood Hits	231	Shared Neighborhood Hits	45
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.061398 (rank : 298)
Query Neighborhood Hits	156	Target Neighborhood Hits	155	Shared Neighborhood Hits	35
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.064670 (rank : 280)
Query Neighborhood Hits	156	Target Neighborhood Hits	144	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.059051 (rank : 316)
Query Neighborhood Hits	156	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA44_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.054846 (rank : 342)
Query Neighborhood Hits	156	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.062470 (rank : 292)
Query Neighborhood Hits	156	Target Neighborhood Hits	194	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.077018 (rank : 211)
Query Neighborhood Hits	156	Target Neighborhood Hits	204	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.091082 (rank : 131)
Query Neighborhood Hits	156	Target Neighborhood Hits	288	Shared Neighborhood Hits	66
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.076590 (rank : 213)
Query Neighborhood Hits	156	Target Neighborhood Hits	236	Shared Neighborhood Hits	44
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.098674 (rank : 105)
Query Neighborhood Hits	156	Target Neighborhood Hits	331	Shared Neighborhood Hits	63
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.083831 (rank : 176)
Query Neighborhood Hits	156	Target Neighborhood Hits	270	Shared Neighborhood Hits	51
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.089548 (rank : 145)
Query Neighborhood Hits	156	Target Neighborhood Hits	257	Shared Neighborhood Hits	52
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.078580 (rank : 201)
Query Neighborhood Hits	156	Target Neighborhood Hits	207	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.085654 (rank : 165)
Query Neighborhood Hits	156	Target Neighborhood Hits	269	Shared Neighborhood Hits	53
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA92_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.067404 (rank : 262)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.064982 (rank : 278)
Query Neighborhood Hits	156	Target Neighborhood Hits	203	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.053136 (rank : 353)
Query Neighborhood Hits	156	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.062901 (rank : 289)
Query Neighborhood Hits	156	Target Neighborhood Hits	185	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.059681 (rank : 312)
Query Neighborhood Hits	156	Target Neighborhood Hits	173	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.070915 (rank : 238)
Query Neighborhood Hits	156	Target Neighborhood Hits	804	Shared Neighborhood Hits	66
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.073126 (rank : 231)
Query Neighborhood Hits	156	Target Neighborhood Hits	838	Shared Neighborhood Hits	72
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA4_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.051815 (rank : 356)
Query Neighborhood Hits	156	Target Neighborhood Hits	708	Shared Neighborhood Hits	52
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.054952 (rank : 341)
Query Neighborhood Hits	156	Target Neighborhood Hits	584	Shared Neighborhood Hits	54
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.071400 (rank : 235)
Query Neighborhood Hits	156	Target Neighborhood Hits	976	Shared Neighborhood Hits	74
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.071873 (rank : 233)
Query Neighborhood Hits	156	Target Neighborhood Hits	828	Shared Neighborhood Hits	76
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.071188 (rank : 237)
Query Neighborhood Hits	156	Target Neighborhood Hits	692	Shared Neighborhood Hits	61
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.070355 (rank : 242)
Query Neighborhood Hits	156	Target Neighborhood Hits	722	Shared Neighborhood Hits	64
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.062168 (rank : 293)
Query Neighborhood Hits	156	Target Neighborhood Hits	461	Shared Neighborhood Hits	51
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.062562 (rank : 290)
Query Neighborhood Hits	156	Target Neighborhood Hits	715	Shared Neighborhood Hits	58
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.064205 (rank : 282)
Query Neighborhood Hits	156	Target Neighborhood Hits	614	Shared Neighborhood Hits	61
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.068297 (rank : 255)
Query Neighborhood Hits	156	Target Neighborhood Hits	588	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.068151 (rank : 256)
Query Neighborhood Hits	156	Target Neighborhood Hits	624	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.085205 (rank : 168)
Query Neighborhood Hits	156	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.102879 (rank : 96)
Query Neighborhood Hits	156	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.111139 (rank : 79)
Query Neighborhood Hits	156	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.096096 (rank : 115)
Query Neighborhood Hits	156	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.113535 (rank : 77)
Query Neighborhood Hits	156	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.087674 (rank : 157)
Query Neighborhood Hits	156	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.059804 (rank : 310)
Query Neighborhood Hits	156	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.088716 (rank : 153)
Query Neighborhood Hits	156	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.090481 (rank : 136)
Query Neighborhood Hits	156	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.086873 (rank : 160)
Query Neighborhood Hits	156	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.056371 (rank : 333)
Query Neighborhood Hits	156	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE4A_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.108162 (rank : 83)
Query Neighborhood Hits	156	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.070330 (rank : 243)
Query Neighborhood Hits	156	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LDLR_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.051346 (rank : 360)
Query Neighborhood Hits	156	Target Neighborhood Hits	375	Shared Neighborhood Hits	60
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.062507 (rank : 291)
Query Neighborhood Hits	156	Target Neighborhood Hits	602	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.060958 (rank : 302)
Query Neighborhood Hits	156	Target Neighborhood Hits	606	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.061064 (rank : 301)
Query Neighborhood Hits	156	Target Neighborhood Hits	617	Shared Neighborhood Hits	77
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.050485 (rank : 365)
Query Neighborhood Hits	156	Target Neighborhood Hits	573	Shared Neighborhood Hits	75
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LTB1L_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.078204 (rank : 203)
Query Neighborhood Hits	156	Target Neighborhood Hits	553	Shared Neighborhood Hits	72
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.078149 (rank : 204)
Query Neighborhood Hits	156	Target Neighborhood Hits	502	Shared Neighborhood Hits	69
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.080661 (rank : 193)
Query Neighborhood Hits	156	Target Neighborhood Hits	552	Shared Neighborhood Hits	71
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.073752 (rank : 226)
Query Neighborhood Hits	156	Target Neighborhood Hits	502	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.076280 (rank : 214)
Query Neighborhood Hits	156	Target Neighborhood Hits	475	Shared Neighborhood Hits	72
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.080318 (rank : 194)
Query Neighborhood Hits	156	Target Neighborhood Hits	607	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MATN2_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.068900 (rank : 251)
Query Neighborhood Hits	156	Target Neighborhood Hits	365	Shared Neighborhood Hits	53
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.066755 (rank : 266)
Query Neighborhood Hits	156	Target Neighborhood Hits	356	Shared Neighborhood Hits	57
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.051271 (rank : 362)
Query Neighborhood Hits	156	Target Neighborhood Hits	268	Shared Neighborhood Hits	44
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.052245 (rank : 355)
Query Neighborhood Hits	156	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.061345 (rank : 299)
Query Neighborhood Hits	156	Target Neighborhood Hits	287	Shared Neighborhood Hits	50
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.053857 (rank : 352)
Query Neighborhood Hits	156	Target Neighborhood Hits	277	Shared Neighborhood Hits	41
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MEGF8_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.075032 (rank : 222)
Query Neighborhood Hits	156	Target Neighborhood Hits	528	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.076100 (rank : 215)
Query Neighborhood Hits	156	Target Neighborhood Hits	520	Shared Neighborhood Hits	66
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.075262 (rank : 221)
Query Neighborhood Hits	156	Target Neighborhood Hits	557	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.077708 (rank : 206)
Query Neighborhood Hits	156	Target Neighborhood Hits	896	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MUC2_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.118887 (rank : 68)
Query Neighborhood Hits	156	Target Neighborhood Hits	906	Shared Neighborhood Hits	78
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NAGPA_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.069693 (rank : 245)
Query Neighborhood Hits	156	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.067431 (rank : 261)
Query Neighborhood Hits	156	Target Neighborhood Hits	308	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NFX1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.065150 (rank : 276)
Query Neighborhood Hits	156	Target Neighborhood Hits	405	Shared Neighborhood Hits	57
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.066198 (rank : 270)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	61
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.065175 (rank : 275)
Query Neighborhood Hits	156	Target Neighborhood Hits	335	Shared Neighborhood Hits	61
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.066949 (rank : 265)
Query Neighborhood Hits	156	Target Neighborhood Hits	456	Shared Neighborhood Hits	66
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.065665 (rank : 273)
Query Neighborhood Hits	156	Target Neighborhood Hits	338	Shared Neighborhood Hits	60
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC2_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.089584 (rank : 143)
Query Neighborhood Hits	156	Target Neighborhood Hits	1069	Shared Neighborhood Hits	76
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.090543 (rank : 135)
Query Neighborhood Hits	156	Target Neighborhood Hits	975	Shared Neighborhood Hits	83
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NTNG1_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.055355 (rank : 339)
Query Neighborhood Hits	156	Target Neighborhood Hits	247	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.053871 (rank : 351)
Query Neighborhood Hits	156	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.058641 (rank : 319)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.059719 (rank : 311)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCSK5_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.070498 (rank : 241)
Query Neighborhood Hits	156	Target Neighborhood Hits	613	Shared Neighborhood Hits	81
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PGBM_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.055796 (rank : 335)
Query Neighborhood Hits	156	Target Neighborhood Hits	1113	Shared Neighborhood Hits	78
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.056911 (rank : 329)
Query Neighborhood Hits	156	Target Neighborhood Hits	1073	Shared Neighborhood Hits	78
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PROP_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.089015 (rank : 149)
Query Neighborhood Hits	156	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.094725 (rank : 121)
Query Neighborhood Hits	156	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROS_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.063322 (rank : 287)
Query Neighborhood Hits	156	Target Neighborhood Hits	340	Shared Neighborhood Hits	51
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

RECK_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.073717 (rank : 227)
Query Neighborhood Hits	156	Target Neighborhood Hits	189	Shared Neighborhood Hits	53
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.073388 (rank : 228)
Query Neighborhood Hits	156	Target Neighborhood Hits	158	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RSPO4_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.067333 (rank : 264)
Query Neighborhood Hits	156	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SCUB3_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.069546 (rank : 247)
Query Neighborhood Hits	156	Target Neighborhood Hits	428	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.071240 (rank : 236)
Query Neighborhood Hits	156	Target Neighborhood Hits	442	Shared Neighborhood Hits	61
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SREC2_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.101599 (rank : 97)
Query Neighborhood Hits	156	Target Neighborhood Hits	605	Shared Neighborhood Hits	79
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SUSD1_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.055396 (rank : 338)
Query Neighborhood Hits	156	Target Neighborhood Hits	285	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TECTA_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.084650 (rank : 169)
Query Neighborhood Hits	156	Target Neighborhood Hits	239	Shared Neighborhood Hits	52
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.089784 (rank : 142)
Query Neighborhood Hits	156	Target Neighborhood Hits	244	Shared Neighborhood Hits	52
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.057711 (rank : 323)
Query Neighborhood Hits	156	Target Neighborhood Hits	211	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.059960 (rank : 308)
Query Neighborhood Hits	156	Target Neighborhood Hits	214	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENA_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.073354 (rank : 229)
Query Neighborhood Hits	156	Target Neighborhood Hits	631	Shared Neighborhood Hits	76
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.071866 (rank : 234)
Query Neighborhood Hits	156	Target Neighborhood Hits	596	Shared Neighborhood Hits	72
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

THSD1_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.060406 (rank : 307)
Query Neighborhood Hits	156	Target Neighborhood Hits	136	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.058009 (rank : 322)
Query Neighborhood Hits	156	Target Neighborhood Hits	153	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TRBM_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.092327 (rank : 126)
Query Neighborhood Hits	156	Target Neighborhood Hits	339	Shared Neighborhood Hits	61
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.081951 (rank : 189)
Query Neighborhood Hits	156	Target Neighborhood Hits	361	Shared Neighborhood Hits	67
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP2_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.153075 (rank : 47)
Query Neighborhood Hits	156	Target Neighborhood Hits	352	Shared Neighborhood Hits	104
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.058503 (rank : 320)
Query Neighborhood Hits	156	Target Neighborhood Hits	250	Shared Neighborhood Hits	46
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.060586 (rank : 306)
Query Neighborhood Hits	156	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.066056 (rank : 272)
Query Neighborhood Hits	156	Target Neighborhood Hits	277	Shared Neighborhood Hits	50
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.067389 (rank : 263)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.068621 (rank : 252)
Query Neighborhood Hits	156	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.069181 (rank : 248)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	51
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.054060 (rank : 349)
Query Neighborhood Hits	156	Target Neighborhood Hits	600	Shared Neighborhood Hits	60
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.059258 (rank : 314)
Query Neighborhood Hits	156	Target Neighborhood Hits	626	Shared Neighborhood Hits	61
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

WIF1_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.082562 (rank : 185)
Query Neighborhood Hits	156	Target Neighborhood Hits	392	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.083540 (rank : 178)
Query Neighborhood Hits	156	Target Neighborhood Hits	393	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

Hits sorted by NC score

CYR61_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	156	Target Neighborhood Hits	156	Shared Neighborhood Hits	156
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

CYR61_HUMAN
NC score	0.996395 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	156	Target Neighborhood Hits	159	Shared Neighborhood Hits	148
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CTGF_HUMAN
NC score	0.957833 (rank : 3)	θ value	3.79596e-99 (rank : 3)
Query Neighborhood Hits	156	Target Neighborhood Hits	128	Shared Neighborhood Hits	85
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
NC score	0.956743 (rank : 4)	θ value	4.34313e-95 (rank : 4)
Query Neighborhood Hits	156	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

WISP1_MOUSE
NC score	0.946402 (rank : 5)	θ value	5.51964e-74 (rank : 7)
Query Neighborhood Hits	156	Target Neighborhood Hits	123	Shared Neighborhood Hits	92
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

NOV_HUMAN
NC score	0.945954 (rank : 6)	θ value	1.44917e-82 (rank : 5)
Query Neighborhood Hits	156	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
NC score	0.945891 (rank : 7)	θ value	3.0217e-80 (rank : 6)
Query Neighborhood Hits	156	Target Neighborhood Hits	130	Shared Neighborhood Hits	90
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

WISP1_HUMAN
NC score	0.944334 (rank : 8)	θ value	1.96316e-71 (rank : 8)
Query Neighborhood Hits	156	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP3_HUMAN
NC score	0.933422 (rank : 9)	θ value	4.39379e-55 (rank : 9)
Query Neighborhood Hits	156	Target Neighborhood Hits	87	Shared Neighborhood Hits	74
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

WISP2_HUMAN
NC score	0.931154 (rank : 10)	θ value	1.61718e-49 (rank : 10)
Query Neighborhood Hits	156	Target Neighborhood Hits	126	Shared Neighborhood Hits	93
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
NC score	0.918924 (rank : 11)	θ value	6.14528e-49 (rank : 11)
Query Neighborhood Hits	156	Target Neighborhood Hits	129	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ESM1_MOUSE
NC score	0.375707 (rank : 12)	θ value	0.00665767 (rank : 30)
Query Neighborhood Hits	156	Target Neighborhood Hits	107	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_HUMAN
NC score	0.344327 (rank : 13)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	156	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

CRIM1_HUMAN
NC score	0.304194 (rank : 14)	θ value	0.00134147 (rank : 23)
Query Neighborhood Hits	156	Target Neighborhood Hits	362	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRDL2_HUMAN
NC score	0.288781 (rank : 15)	θ value	0.0431538 (rank : 48)
Query Neighborhood Hits	156	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

BMPER_MOUSE
NC score	0.288693 (rank : 16)	θ value	0.0113563 (rank : 36)
Query Neighborhood Hits	156	Target Neighborhood Hits	194	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BMPER_HUMAN
NC score	0.280996 (rank : 17)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	156	Target Neighborhood Hits	175	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CRDL2_MOUSE
NC score	0.280586 (rank : 18)	θ value	1.09739e-05 (rank : 14)
Query Neighborhood Hits	156	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

HTRA4_HUMAN
NC score	0.276882 (rank : 19)	θ value	0.00134147 (rank : 24)
Query Neighborhood Hits	156	Target Neighborhood Hits	119	Shared Neighborhood Hits	33
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

CRDL1_MOUSE
NC score	0.269410 (rank : 20)	θ value	0.00020696 (rank : 17)
Query Neighborhood Hits	156	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_HUMAN
NC score	0.265503 (rank : 21)	θ value	0.000270298 (rank : 18)
Query Neighborhood Hits	156	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

HTRA1_HUMAN
NC score	0.255557 (rank : 22)	θ value	0.000786445 (rank : 21)
Query Neighborhood Hits	156	Target Neighborhood Hits	155	Shared Neighborhood Hits	38
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HTRA1_MOUSE
NC score	0.253766 (rank : 23)	θ value	9.29e-05 (rank : 15)
Query Neighborhood Hits	156	Target Neighborhood Hits	140	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

HTRA3_HUMAN
NC score	0.248046 (rank : 24)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	156	Target Neighborhood Hits	152	Shared Neighborhood Hits	38
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
NC score	0.246545 (rank : 25)	θ value	0.000270298 (rank : 19)
Query Neighborhood Hits	156	Target Neighborhood Hits	156	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

SSPO_MOUSE
NC score	0.208684 (rank : 26)	θ value	0.00298849 (rank : 29)
Query Neighborhood Hits	156	Target Neighborhood Hits	800	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

IBP2_MOUSE
NC score	0.207591 (rank : 27)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	156	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP7_MOUSE
NC score	0.198856 (rank : 28)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	156	Target Neighborhood Hits	230	Shared Neighborhood Hits	37
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

NELL1_HUMAN
NC score	0.195382 (rank : 29)	θ value	0.00134147 (rank : 25)
Query Neighborhood Hits	156	Target Neighborhood Hits	451	Shared Neighborhood Hits	83
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

FRAS1_HUMAN
NC score	0.190706 (rank : 30)	θ value	0.000461057 (rank : 20)
Query Neighborhood Hits	156	Target Neighborhood Hits	759	Shared Neighborhood Hits	114
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
NC score	0.189844 (rank : 31)	θ value	0.00175202 (rank : 27)
Query Neighborhood Hits	156	Target Neighborhood Hits	747	Shared Neighborhood Hits	114
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

IBP2_HUMAN
NC score	0.189007 (rank : 32)	θ value	0.0961366 (rank : 56)
Query Neighborhood Hits	156	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP7_HUMAN
NC score	0.184157 (rank : 33)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	156	Target Neighborhood Hits	220	Shared Neighborhood Hits	33
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

NELL2_HUMAN
NC score	0.183715 (rank : 34)	θ value	0.00102713 (rank : 22)
Query Neighborhood Hits	156	Target Neighborhood Hits	449	Shared Neighborhood Hits	83
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

ZAN_MOUSE
NC score	0.183350 (rank : 35)	θ value	0.00134147 (rank : 26)
Query Neighborhood Hits	156	Target Neighborhood Hits	808	Shared Neighborhood Hits	101
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MUC5B_HUMAN
NC score	0.182837 (rank : 36)	θ value	0.0148317 (rank : 39)
Query Neighborhood Hits	156	Target Neighborhood Hits	1020	Shared Neighborhood Hits	92
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TSP1_HUMAN
NC score	0.181986 (rank : 37)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	156	Target Neighborhood Hits	389	Shared Neighborhood Hits	110
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

NELL2_MOUSE
NC score	0.180132 (rank : 38)	θ value	0.0148317 (rank : 40)
Query Neighborhood Hits	156	Target Neighborhood Hits	436	Shared Neighborhood Hits	83
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

TSP1_MOUSE
NC score	0.179262 (rank : 39)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	156	Target Neighborhood Hits	396	Shared Neighborhood Hits	112
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

SPON1_HUMAN
NC score	0.176002 (rank : 40)	θ value	0.0193708 (rank : 43)
Query Neighborhood Hits	156	Target Neighborhood Hits	117	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
NC score	0.174591 (rank : 41)	θ value	0.0193708 (rank : 44)
Query Neighborhood Hits	156	Target Neighborhood Hits	123	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

VWF_HUMAN
NC score	0.166778 (rank : 42)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	156	Target Neighborhood Hits	396	Shared Neighborhood Hits	87
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
NC score	0.166620 (rank : 43)	θ value	0.0252991 (rank : 47)
Query Neighborhood Hits	156	Target Neighborhood Hits	381	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

IBP5_MOUSE
NC score	0.164232 (rank : 44)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	156	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_HUMAN
NC score	0.162361 (rank : 45)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	156	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

TSP2_HUMAN
NC score	0.154004 (rank : 46)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	156	Target Neighborhood Hits	359	Shared Neighborhood Hits	106
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
NC score	0.153075 (rank : 47)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	156	Target Neighborhood Hits	352	Shared Neighborhood Hits	104
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

KAZD1_HUMAN
NC score	0.152976 (rank : 48)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	156	Target Neighborhood Hits	248	Shared Neighborhood Hits	39
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
NC score	0.147867 (rank : 49)	θ value	0.279714 (rank : 69)
Query Neighborhood Hits	156	Target Neighborhood Hits	281	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

IBP4_MOUSE
NC score	0.140274 (rank : 50)	θ value	0.0148317 (rank : 38)
Query Neighborhood Hits	156	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP3_HUMAN
NC score	0.139946 (rank : 51)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	156	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

ZAN_HUMAN
NC score	0.139469 (rank : 52)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	156	Target Neighborhood Hits	679	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ATL2_HUMAN
NC score	0.139121 (rank : 53)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	156	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
NC score	0.137109 (rank : 54)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	156	Target Neighborhood Hits	137	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

SREC_HUMAN
NC score	0.134755 (rank : 55)	θ value	0.00665767 (rank : 31)
Query Neighborhood Hits	156	Target Neighborhood Hits	645	Shared Neighborhood Hits	84
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

IBP4_HUMAN
NC score	0.133643 (rank : 56)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	156	Target Neighborhood Hits	52	Shared Neighborhood Hits	22
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP1_HUMAN
NC score	0.132917 (rank : 57)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	156	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

KR104_HUMAN
NC score	0.131458 (rank : 58)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	156	Target Neighborhood Hits	313	Shared Neighborhood Hits	71
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

IBP1_MOUSE
NC score	0.129947 (rank : 59)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	156	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

MEGF6_HUMAN
NC score	0.128962 (rank : 60)	θ value	0.00228821 (rank : 28)
Query Neighborhood Hits	156	Target Neighborhood Hits	671	Shared Neighborhood Hits	102
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

IBP3_MOUSE
NC score	0.127605 (rank : 61)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	156	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

ATS1_MOUSE
NC score	0.124360 (rank : 62)	θ value	0.0193708 (rank : 41)
Query Neighborhood Hits	156	Target Neighborhood Hits	158	Shared Neighborhood Hits	61
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

KRA59_HUMAN
NC score	0.121305 (rank : 63)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	59
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA58_HUMAN
NC score	0.120785 (rank : 64)	θ value	0.125558 (rank : 59)
Query Neighborhood Hits	156	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ATS12_HUMAN
NC score	0.120220 (rank : 65)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	156	Target Neighborhood Hits	251	Shared Neighborhood Hits	63
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS9_HUMAN
NC score	0.119372 (rank : 66)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	156	Target Neighborhood Hits	219	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

SLIT2_HUMAN
NC score	0.119125 (rank : 67)	θ value	8.40245e-06 (rank : 12)
Query Neighborhood Hits	156	Target Neighborhood Hits	708	Shared Neighborhood Hits	75
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

MUC2_HUMAN
NC score	0.118887 (rank : 68)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	156	Target Neighborhood Hits	906	Shared Neighborhood Hits	78
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ATS19_MOUSE
NC score	0.118812 (rank : 69)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	156	Target Neighborhood Hits	188	Shared Neighborhood Hits	60
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_MOUSE
NC score	0.118650 (rank : 70)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	156	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS19_HUMAN
NC score	0.117879 (rank : 71)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	156	Target Neighborhood Hits	203	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

SLIT2_MOUSE
NC score	0.117838 (rank : 72)	θ value	8.40245e-06 (rank : 13)
Query Neighborhood Hits	156	Target Neighborhood Hits	684	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

KR107_HUMAN
NC score	0.116985 (rank : 73)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	156	Target Neighborhood Hits	330	Shared Neighborhood Hits	71
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

MCSP_MOUSE
NC score	0.115358 (rank : 74)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	156	Target Neighborhood Hits	108	Shared Neighborhood Hits	26
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

ATS1_HUMAN
NC score	0.114401 (rank : 75)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	156	Target Neighborhood Hits	159	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS12_MOUSE
NC score	0.114109 (rank : 76)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	156	Target Neighborhood Hits	220	Shared Neighborhood Hits	63
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

LCE1E_HUMAN
NC score	0.113535 (rank : 77)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	156	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

CHRD_HUMAN
NC score	0.111564 (rank : 78)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	156	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

LCE1C_HUMAN
NC score	0.111139 (rank : 79)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	156	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

ATS17_HUMAN
NC score	0.111118 (rank : 80)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	156	Target Neighborhood Hits	194	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATL3_HUMAN
NC score	0.108840 (rank : 81)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	156	Target Neighborhood Hits	414	Shared Neighborhood Hits	67
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

GRN_MOUSE
NC score	0.108227 (rank : 82)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	156	Target Neighborhood Hits	248	Shared Neighborhood Hits	55
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

LCE4A_HUMAN
NC score	0.108162 (rank : 83)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	156	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

ATS20_HUMAN
NC score	0.107413 (rank : 84)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	156	Target Neighborhood Hits	192	Shared Neighborhood Hits	65
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

AGRIN_HUMAN
NC score	0.107157 (rank : 85)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	156	Target Neighborhood Hits	582	Shared Neighborhood Hits	82
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ATS18_MOUSE
NC score	0.106610 (rank : 86)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	156	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_HUMAN
NC score	0.106219 (rank : 87)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	156	Target Neighborhood Hits	208	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

KR106_HUMAN
NC score	0.105820 (rank : 88)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	156	Target Neighborhood Hits	347	Shared Neighborhood Hits	77
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

JAG1_HUMAN
NC score	0.105459 (rank : 89)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	156	Target Neighborhood Hits	514	Shared Neighborhood Hits	77
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

ATS15_HUMAN
NC score	0.105314 (rank : 90)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	156	Target Neighborhood Hits	151	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS16_MOUSE
NC score	0.105256 (rank : 91)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	156	Target Neighborhood Hits	179	Shared Neighborhood Hits	61
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

JAG1_MOUSE
NC score	0.104544 (rank : 92)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	156	Target Neighborhood Hits	518	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

CHRD_MOUSE
NC score	0.104349 (rank : 93)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	156	Target Neighborhood Hits	102	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

ATS18_HUMAN
NC score	0.104206 (rank : 94)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	156	Target Neighborhood Hits	169	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS3_HUMAN
NC score	0.104179 (rank : 95)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	156	Target Neighborhood Hits	179	Shared Neighborhood Hits	62
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

LCE1B_HUMAN
NC score	0.102879 (rank : 96)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	156	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

SREC2_MOUSE
NC score	0.101599 (rank : 97)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	156	Target Neighborhood Hits	605	Shared Neighborhood Hits	79
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

STAB2_HUMAN
NC score	0.101537 (rank : 98)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	156	Target Neighborhood Hits	534	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ATS14_HUMAN
NC score	0.100390 (rank : 99)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	156	Target Neighborhood Hits	382	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

STAB1_HUMAN
NC score	0.099634 (rank : 100)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	156	Target Neighborhood Hits	546	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ATL5_HUMAN
NC score	0.099601 (rank : 101)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	156	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

STAB2_MOUSE
NC score	0.098888 (rank : 102)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	156	Target Neighborhood Hits	528	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

ATS2_MOUSE
NC score	0.098836 (rank : 103)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	156	Target Neighborhood Hits	179	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

NOTC4_HUMAN
NC score	0.098757 (rank : 104)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	156	Target Neighborhood Hits	905	Shared Neighborhood Hits	82
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

KRA53_HUMAN
NC score	0.098674 (rank : 105)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	156	Target Neighborhood Hits	331	Shared Neighborhood Hits	63
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

ATL1_HUMAN
NC score	0.098626 (rank : 106)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	156	Target Neighborhood Hits	93	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

NOTC1_MOUSE
NC score	0.098444 (rank : 107)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	156	Target Neighborhood Hits	916	Shared Neighborhood Hits	79
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC4_MOUSE
NC score	0.098429 (rank : 108)	θ value	0.163984 (rank : 62)
Query Neighborhood Hits	156	Target Neighborhood Hits	872	Shared Neighborhood Hits	84
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

STAB1_MOUSE
NC score	0.098374 (rank : 109)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	156	Target Neighborhood Hits	566	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

SLIT1_HUMAN
NC score	0.098324 (rank : 110)	θ value	0.0113563 (rank : 37)
Query Neighborhood Hits	156	Target Neighborhood Hits	700	Shared Neighborhood Hits	70
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SREC2_HUMAN
NC score	0.097899 (rank : 111)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	156	Target Neighborhood Hits	645	Shared Neighborhood Hits	74
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

NOTC3_HUMAN
NC score	0.097766 (rank : 112)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	156	Target Neighborhood Hits	1062	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CO1A1_MOUSE
NC score	0.097751 (rank : 113)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	156	Target Neighborhood Hits	457	Shared Neighborhood Hits	39
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

DLK_MOUSE
NC score	0.097595 (rank : 114)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	156	Target Neighborhood Hits	374	Shared Neighborhood Hits	67
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

LCE1D_HUMAN
NC score	0.096096 (rank : 115)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	156	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

SLIT1_MOUSE
NC score	0.095951 (rank : 116)	θ value	0.00869519 (rank : 34)
Query Neighborhood Hits	156	Target Neighborhood Hits	715	Shared Neighborhood Hits	70
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

KR101_HUMAN
NC score	0.095937 (rank : 117)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	156	Target Neighborhood Hits	261	Shared Neighborhood Hits	63
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

JAG2_HUMAN
NC score	0.095311 (rank : 118)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	156	Target Neighborhood Hits	491	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

SLIT3_MOUSE
NC score	0.095041 (rank : 119)	θ value	0.00869519 (rank : 35)
Query Neighborhood Hits	156	Target Neighborhood Hits	700	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ATS7_HUMAN
NC score	0.094755 (rank : 120)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	156	Target Neighborhood Hits	169	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

PROP_MOUSE
NC score	0.094725 (rank : 121)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	156	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

JAG2_MOUSE
NC score	0.093834 (rank : 122)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	156	Target Neighborhood Hits	504	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

EGFL9_MOUSE
NC score	0.093663 (rank : 123)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	156	Target Neighborhood Hits	379	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

NOTC2_HUMAN
NC score	0.092730 (rank : 124)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	156	Target Neighborhood Hits	1113	Shared Neighborhood Hits	80
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KR108_HUMAN
NC score	0.092435 (rank : 125)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	156	Target Neighborhood Hits	226	Shared Neighborhood Hits	54
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

TRBM_HUMAN
NC score	0.092327 (rank : 126)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	156	Target Neighborhood Hits	339	Shared Neighborhood Hits	61
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

FBN1_HUMAN
NC score	0.092317 (rank : 127)	θ value	0.365318 (rank : 72)
Query Neighborhood Hits	156	Target Neighborhood Hits	557	Shared Neighborhood Hits	77
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

NOTC1_HUMAN
NC score	0.092288 (rank : 128)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	156	Target Neighborhood Hits	906	Shared Neighborhood Hits	84
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SLIT3_HUMAN
NC score	0.092177 (rank : 129)	θ value	0.0193708 (rank : 42)
Query Neighborhood Hits	156	Target Neighborhood Hits	682	Shared Neighborhood Hits	64
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

HMCN1_HUMAN
NC score	0.092122 (rank : 130)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	156	Target Neighborhood Hits	983	Shared Neighborhood Hits	106
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KRA51_HUMAN
NC score	0.091082 (rank : 131)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	156	Target Neighborhood Hits	288	Shared Neighborhood Hits	66
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

ATS13_HUMAN
NC score	0.090850 (rank : 132)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	156	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

CI094_HUMAN
NC score	0.090687 (rank : 133)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

SOSD1_HUMAN
NC score	0.090631 (rank : 134)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	156	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q6X4U4, Q96HJ7, Q9Y3U3	Gene names	SOSTDC1, USAG1
Domain Architecture	No domain graphic available
Description	Sclerostin domain-containing protein 1 precursor (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1).

NOTC3_MOUSE
NC score	0.090543 (rank : 135)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	156	Target Neighborhood Hits	975	Shared Neighborhood Hits	83
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LCE2C_HUMAN
NC score	0.090481 (rank : 136)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	156	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

FBN2_HUMAN
NC score	0.090305 (rank : 137)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	156	Target Neighborhood Hits	560	Shared Neighborhood Hits	81
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

HTRA2_MOUSE
NC score	0.090206 (rank : 138)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	156	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

ATS6_HUMAN
NC score	0.090161 (rank : 139)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	156	Target Neighborhood Hits	141	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS2_HUMAN
NC score	0.090105 (rank : 140)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	156	Target Neighborhood Hits	179	Shared Neighborhood Hits	56
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

HTRA2_HUMAN
NC score	0.089940 (rank : 141)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	156	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

TECTA_MOUSE
NC score	0.089784 (rank : 142)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	156	Target Neighborhood Hits	244	Shared Neighborhood Hits	52
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

NOTC2_MOUSE
NC score	0.089584 (rank : 143)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	156	Target Neighborhood Hits	1069	Shared Neighborhood Hits	76
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DLL3_HUMAN
NC score	0.089554 (rank : 144)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	156	Target Neighborhood Hits	419	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

KRA55_HUMAN
NC score	0.089548 (rank : 145)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	156	Target Neighborhood Hits	257	Shared Neighborhood Hits	52
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

FBN3_HUMAN
NC score	0.089496 (rank : 146)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	156	Target Neighborhood Hits	543	Shared Neighborhood Hits	77
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN1_MOUSE
NC score	0.089313 (rank : 147)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	156	Target Neighborhood Hits	563	Shared Neighborhood Hits	76
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

DNER_HUMAN
NC score	0.089142 (rank : 148)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	156	Target Neighborhood Hits	460	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

PROP_HUMAN
NC score	0.089015 (rank : 149)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	156	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

FBN2_MOUSE
NC score	0.088970 (rank : 150)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	156	Target Neighborhood Hits	549	Shared Neighborhood Hits	79
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

SEM5A_HUMAN
NC score	0.088878 (rank : 151)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	156	Target Neighborhood Hits	177	Shared Neighborhood Hits	58
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATS13_MOUSE
NC score	0.088746 (rank : 152)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	156	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

LCE2B_HUMAN
NC score	0.088716 (rank : 153)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	156	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

SOSD1_MOUSE
NC score	0.088549 (rank : 154)	θ value	0.163984 (rank : 63)
Query Neighborhood Hits	156	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN4, Q8CF09	Gene names	Sostdc1, Sostl, Usag1
Domain Architecture	No domain graphic available
Description	Sclerostin domain-containing protein 1 precursor (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1) (Sclerostin-like protein).

DLL4_MOUSE
NC score	0.088523 (rank : 155)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	156	Target Neighborhood Hits	440	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

CO6_HUMAN
NC score	0.088447 (rank : 156)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	156	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

LCE1F_HUMAN
NC score	0.087674 (rank : 157)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	156	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

BAI1_MOUSE
NC score	0.087317 (rank : 158)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	156	Target Neighborhood Hits	340	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

DNER_MOUSE
NC score	0.087042 (rank : 159)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	156	Target Neighborhood Hits	413	Shared Neighborhood Hits	61
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

LCE2D_HUMAN
NC score	0.086873 (rank : 160)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	156	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

DLL3_MOUSE
NC score	0.086723 (rank : 161)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	156	Target Neighborhood Hits	399	Shared Neighborhood Hits	62
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

KR109_HUMAN
NC score	0.086692 (rank : 162)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	156	Target Neighborhood Hits	226	Shared Neighborhood Hits	54
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

DLL1_MOUSE
NC score	0.086268 (rank : 163)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	156	Target Neighborhood Hits	456	Shared Neighborhood Hits	68
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

GRN_HUMAN
NC score	0.085696 (rank : 164)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	156	Target Neighborhood Hits	268	Shared Neighborhood Hits	53
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KRA57_HUMAN
NC score	0.085654 (rank : 165)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	156	Target Neighborhood Hits	269	Shared Neighborhood Hits	53
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

DLL4_HUMAN
NC score	0.085621 (rank : 166)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	156	Target Neighborhood Hits	435	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

SEM5A_MOUSE
NC score	0.085388 (rank : 167)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	156	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

LCE1A_HUMAN
NC score	0.085205 (rank : 168)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	156	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

TECTA_HUMAN
NC score	0.084650 (rank : 169)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	156	Target Neighborhood Hits	239	Shared Neighborhood Hits	52
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

KR105_HUMAN
NC score	0.084628 (rank : 170)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	156	Target Neighborhood Hits	271	Shared Neighborhood Hits	62
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

DLK_HUMAN
NC score	0.084603 (rank : 171)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	156	Target Neighborhood Hits	401	Shared Neighborhood Hits	64
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

CFC1_HUMAN
NC score	0.084515 (rank : 172)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	156	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

KR10C_HUMAN
NC score	0.084347 (rank : 173)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	156	Target Neighborhood Hits	219	Shared Neighborhood Hits	55
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

BAI1_HUMAN
NC score	0.083905 (rank : 174)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	156	Target Neighborhood Hits	375	Shared Neighborhood Hits	57
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

LTBP2_MOUSE
NC score	0.083893 (rank : 175)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	156	Target Neighborhood Hits	617	Shared Neighborhood Hits	72
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KRA54_HUMAN
NC score	0.083831 (rank : 176)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	156	Target Neighborhood Hits	270	Shared Neighborhood Hits	51
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

FBLN1_HUMAN
NC score	0.083594 (rank : 177)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	156	Target Neighborhood Hits	324	Shared Neighborhood Hits	55
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

WIF1_MOUSE
NC score	0.083540 (rank : 178)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	156	Target Neighborhood Hits	393	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CRUM1_MOUSE
NC score	0.083428 (rank : 179)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	156	Target Neighborhood Hits	444	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM1_HUMAN
NC score	0.083327 (rank : 180)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	156	Target Neighborhood Hits	457	Shared Neighborhood Hits	67
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

EGFL9_HUMAN
NC score	0.083188 (rank : 181)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	156	Target Neighborhood Hits	365	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

DLL1_HUMAN
NC score	0.082883 (rank : 182)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	156	Target Neighborhood Hits	455	Shared Neighborhood Hits	64
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

BAI3_MOUSE
NC score	0.082749 (rank : 183)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	156	Target Neighborhood Hits	250	Shared Neighborhood Hits	56
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CRUM2_HUMAN
NC score	0.082736 (rank : 184)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	156	Target Neighborhood Hits	453	Shared Neighborhood Hits	57
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

WIF1_HUMAN
NC score	0.082562 (rank : 185)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	156	Target Neighborhood Hits	392	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

BAI2_MOUSE
NC score	0.082559 (rank : 186)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	156	Target Neighborhood Hits	323	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ATS8_HUMAN
NC score	0.082431 (rank : 187)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	156	Target Neighborhood Hits	145	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS8_MOUSE
NC score	0.082319 (rank : 188)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	156	Target Neighborhood Hits	139	Shared Neighborhood Hits	51
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

TRBM_MOUSE
NC score	0.081951 (rank : 189)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	156	Target Neighborhood Hits	361	Shared Neighborhood Hits	67
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CREL1_HUMAN
NC score	0.081780 (rank : 190)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	156	Target Neighborhood Hits	441	Shared Neighborhood Hits	61
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

BAI2_HUMAN
NC score	0.081328 (rank : 191)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	156	Target Neighborhood Hits	332	Shared Neighborhood Hits	54
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ATS5_MOUSE
NC score	0.081091 (rank : 192)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	156	Target Neighborhood Hits	147	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

LTBP2_HUMAN
NC score	0.080661 (rank : 193)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	156	Target Neighborhood Hits	552	Shared Neighborhood Hits	71
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP4_MOUSE
NC score	0.080318 (rank : 194)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	156	Target Neighborhood Hits	607	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TENX_HUMAN
NC score	0.079234 (rank : 195)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	156	Target Neighborhood Hits	789	Shared Neighborhood Hits	93
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

KR511_HUMAN
NC score	0.079214 (rank : 196)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	156	Target Neighborhood Hits	231	Shared Neighborhood Hits	45
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

SEM5B_MOUSE
NC score	0.079094 (rank : 197)	θ value	0.21417 (rank : 66)
Query Neighborhood Hits	156	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

CREL1_MOUSE
NC score	0.078924 (rank : 198)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	156	Target Neighborhood Hits	524	Shared Neighborhood Hits	61
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

BAI3_HUMAN
NC score	0.078870 (rank : 199)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	156	Target Neighborhood Hits	246	Shared Neighborhood Hits	53
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

ATS4_MOUSE
NC score	0.078601 (rank : 200)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	156	Target Neighborhood Hits	145	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

KRA56_HUMAN
NC score	0.078580 (rank : 201)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	156	Target Neighborhood Hits	207	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KR102_HUMAN
NC score	0.078527 (rank : 202)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	156	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

LTB1L_HUMAN
NC score	0.078204 (rank : 203)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	156	Target Neighborhood Hits	553	Shared Neighborhood Hits	72
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.078149 (rank : 204)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	156	Target Neighborhood Hits	502	Shared Neighborhood Hits	69
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

KR510_HUMAN
NC score	0.078018 (rank : 205)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	156	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

MEGF9_MOUSE
NC score	0.077708 (rank : 206)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	156	Target Neighborhood Hits	896	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KR10B_HUMAN
NC score	0.077665 (rank : 207)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	156	Target Neighborhood Hits	269	Shared Neighborhood Hits	57
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LAMA2_HUMAN
NC score	0.077488 (rank : 208)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	156	Target Neighborhood Hits	1092	Shared Neighborhood Hits	67
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ATL1_MOUSE
NC score	0.077132 (rank : 209)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	156	Target Neighborhood Hits	80	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATS4_HUMAN
NC score	0.077078 (rank : 210)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	156	Target Neighborhood Hits	138	Shared Neighborhood Hits	48
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

KRA47_HUMAN
NC score	0.077018 (rank : 211)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	156	Target Neighborhood Hits	204	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

ATS5_HUMAN
NC score	0.076778 (rank : 212)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	156	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

KRA52_HUMAN
NC score	0.076590 (rank : 213)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	156	Target Neighborhood Hits	236	Shared Neighborhood Hits	44
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LTBP3_MOUSE
NC score	0.076280 (rank : 214)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	156	Target Neighborhood Hits	475	Shared Neighborhood Hits	72
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MEGF8_MOUSE
NC score	0.076100 (rank : 215)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	156	Target Neighborhood Hits	520	Shared Neighborhood Hits	66
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMB3_MOUSE
NC score	0.076083 (rank : 216)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	156	Target Neighborhood Hits	444	Shared Neighborhood Hits	61
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LTB1S_MOUSE
NC score	0.075931 (rank : 217)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	156	Target Neighborhood Hits	479	Shared Neighborhood Hits	70
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.075776 (rank : 218)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	156	Target Neighborhood Hits	514	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LAMB1_MOUSE
NC score	0.075483 (rank : 219)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	156	Target Neighborhood Hits	919	Shared Neighborhood Hits	65
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

FBLN2_HUMAN
NC score	0.075276 (rank : 220)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	156	Target Neighborhood Hits	392	Shared Neighborhood Hits	61
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

MEGF9_HUMAN
NC score	0.075262 (rank : 221)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	156	Target Neighborhood Hits	557	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF8_HUMAN
NC score	0.075032 (rank : 222)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	156	Target Neighborhood Hits	528	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

FBLN2_MOUSE
NC score	0.074256 (rank : 223)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	156	Target Neighborhood Hits	505	Shared Neighborhood Hits	65
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN1_MOUSE
NC score	0.074148 (rank : 224)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	54
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

SEM5B_HUMAN
NC score	0.074048 (rank : 225)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	156	Target Neighborhood Hits	178	Shared Neighborhood Hits	63
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

LTBP3_HUMAN
NC score	0.073752 (rank : 226)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	156	Target Neighborhood Hits	502	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

RECK_HUMAN
NC score	0.073717 (rank : 227)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	156	Target Neighborhood Hits	189	Shared Neighborhood Hits	53
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
NC score	0.073388 (rank : 228)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	156	Target Neighborhood Hits	158	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TENA_HUMAN
NC score	0.073354 (rank : 229)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	156	Target Neighborhood Hits	631	Shared Neighborhood Hits	76
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

ITB2_MOUSE
NC score	0.073145 (rank : 230)	θ value	0.00869519 (rank : 33)
Query Neighborhood Hits	156	Target Neighborhood Hits	326	Shared Neighborhood Hits	61
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LAMA1_MOUSE
NC score	0.073126 (rank : 231)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	156	Target Neighborhood Hits	838	Shared Neighborhood Hits	72
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KR171_HUMAN
NC score	0.072676 (rank : 232)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	156	Target Neighborhood Hits	144	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LAMA5_MOUSE
NC score	0.071873 (rank : 233)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	156	Target Neighborhood Hits	828	Shared Neighborhood Hits	76
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

TENA_MOUSE
NC score	0.071866 (rank : 234)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	156	Target Neighborhood Hits	596	Shared Neighborhood Hits	72
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

LAMA5_HUMAN
NC score	0.071400 (rank : 235)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	156	Target Neighborhood Hits	976	Shared Neighborhood Hits	74
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

SCUB3_MOUSE
NC score	0.071240 (rank : 236)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	156	Target Neighborhood Hits	442	Shared Neighborhood Hits	61
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMB2_HUMAN
NC score	0.071188 (rank : 237)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	156	Target Neighborhood Hits	692	Shared Neighborhood Hits	61
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMA1_HUMAN
NC score	0.070915 (rank : 238)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	156	Target Neighborhood Hits	804	Shared Neighborhood Hits	66
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KR412_HUMAN
NC score	0.070577 (rank : 239)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	156	Target Neighborhood Hits	178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

LAMA2_MOUSE
NC score	0.070521 (rank : 240)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	156	Target Neighborhood Hits	1198	Shared Neighborhood Hits	70
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

PCSK5_MOUSE
NC score	0.070498 (rank : 241)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	156	Target Neighborhood Hits	613	Shared Neighborhood Hits	81
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

LAMB2_MOUSE
NC score	0.070355 (rank : 242)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	156	Target Neighborhood Hits	722	Shared Neighborhood Hits	64
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LCE5A_HUMAN
NC score	0.070330 (rank : 243)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	156	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LAMC1_HUMAN
NC score	0.069834 (rank : 244)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	156	Target Neighborhood Hits	922	Shared Neighborhood Hits	70
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NAGPA_HUMAN
NC score	0.069693 (rank : 245)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	156	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

C1QR1_HUMAN
NC score	0.069670 (rank : 246)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	156	Target Neighborhood Hits	493	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

SCUB3_HUMAN
NC score	0.069546 (rank : 247)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	156	Target Neighborhood Hits	428	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

UROM_MOUSE
NC score	0.069181 (rank : 248)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	51
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

C1QR1_MOUSE
NC score	0.069079 (rank : 249)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	156	Target Neighborhood Hits	342	Shared Neighborhood Hits	50
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LAMB1_HUMAN
NC score	0.068997 (rank : 250)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	156	Target Neighborhood Hits	1018	Shared Neighborhood Hits	62
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MATN2_HUMAN
NC score	0.068900 (rank : 251)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	156	Target Neighborhood Hits	365	Shared Neighborhood Hits	53
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

UROM_HUMAN
NC score	0.068621 (rank : 252)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	156	Target Neighborhood Hits	284	Shared Neighborhood Hits	48
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FBLN5_HUMAN
NC score	0.068612 (rank : 253)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

PROS_MOUSE
NC score	0.068516 (rank : 254)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	156	Target Neighborhood Hits	330	Shared Neighborhood Hits	53
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

LAMC3_HUMAN
NC score	0.068297 (rank : 255)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	156	Target Neighborhood Hits	588	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
NC score	0.068151 (rank : 256)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	156	Target Neighborhood Hits	624	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

FBLN5_MOUSE
NC score	0.068080 (rank : 257)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	156	Target Neighborhood Hits	317	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LAMC1_MOUSE
NC score	0.067573 (rank : 258)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	156	Target Neighborhood Hits	856	Shared Neighborhood Hits	67
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

KR103_HUMAN
NC score	0.067495 (rank : 259)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	156	Target Neighborhood Hits	212	Shared Neighborhood Hits	48
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

COMP_MOUSE
NC score	0.067459 (rank : 260)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	156	Target Neighborhood Hits	290	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NAGPA_MOUSE
NC score	0.067431 (rank : 261)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	156	Target Neighborhood Hits	308	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

KRA92_HUMAN
NC score	0.067404 (rank : 262)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

TSP4_MOUSE
NC score	0.067389 (rank : 263)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

RSPO4_HUMAN
NC score	0.067333 (rank : 264)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	156	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

NID2_HUMAN
NC score	0.066949 (rank : 265)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	156	Target Neighborhood Hits	456	Shared Neighborhood Hits	66
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

MATN2_MOUSE
NC score	0.066755 (rank : 266)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	156	Target Neighborhood Hits	356	Shared Neighborhood Hits	57
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

CUBN_MOUSE
NC score	0.066538 (rank : 267)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	156	Target Neighborhood Hits	477	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBLN4_MOUSE
NC score	0.066521 (rank : 268)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	156	Target Neighborhood Hits	270	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

LAMA3_MOUSE
NC score	0.066332 (rank : 269)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	156	Target Neighborhood Hits	859	Shared Neighborhood Hits	77
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

NID1_HUMAN
NC score	0.066198 (rank : 270)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	61
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

FBLN4_HUMAN
NC score	0.066107 (rank : 271)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	156	Target Neighborhood Hits	278	Shared Neighborhood Hits	45
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

TSP4_HUMAN
NC score	0.066056 (rank : 272)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	156	Target Neighborhood Hits	277	Shared Neighborhood Hits	50
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

NID2_MOUSE
NC score	0.065665 (rank : 273)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	156	Target Neighborhood Hits	338	Shared Neighborhood Hits	60
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

COMP_HUMAN
NC score	0.065254 (rank : 274)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	156	Target Neighborhood Hits	258	Shared Neighborhood Hits	53
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NID1_MOUSE
NC score	0.065175 (rank : 275)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	156	Target Neighborhood Hits	335	Shared Neighborhood Hits	61
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NFX1_HUMAN
NC score	0.065150 (rank : 276)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	156	Target Neighborhood Hits	405	Shared Neighborhood Hits	57
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

KR414_HUMAN
NC score	0.065020 (rank : 277)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	156	Target Neighborhood Hits	199	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA93_HUMAN
NC score	0.064982 (rank : 278)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	156	Target Neighborhood Hits	203	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KR10A_HUMAN
NC score	0.064680 (rank : 279)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	156	Target Neighborhood Hits	232	Shared Neighborhood Hits	57
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KRA13_HUMAN
NC score	0.064670 (rank : 280)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	156	Target Neighborhood Hits	144	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

CUBN_HUMAN
NC score	0.064665 (rank : 281)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	156	Target Neighborhood Hits	482	Shared Neighborhood Hits	63
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

LAMC2_MOUSE
NC score	0.064205 (rank : 282)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	156	Target Neighborhood Hits	614	Shared Neighborhood Hits	61
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

GAS6_MOUSE
NC score	0.064024 (rank : 283)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	156	Target Neighborhood Hits	343	Shared Neighborhood Hits	53
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN3_HUMAN
NC score	0.063606 (rank : 284)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	156	Target Neighborhood Hits	293	Shared Neighborhood Hits	48
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

ITB7_HUMAN
NC score	0.063482 (rank : 285)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	156	Target Neighborhood Hits	290	Shared Neighborhood Hits	58
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

EMR1_HUMAN
NC score	0.063373 (rank : 286)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	156	Target Neighborhood Hits	382	Shared Neighborhood Hits	55
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

PROS_HUMAN
NC score	0.063322 (rank : 287)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	156	Target Neighborhood Hits	340	Shared Neighborhood Hits	51
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

EGFL7_HUMAN
NC score	0.063296 (rank : 288)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	156	Target Neighborhood Hits	325	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

KRA98_HUMAN
NC score	0.062901 (rank : 289)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	156	Target Neighborhood Hits	185	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

LAMC2_HUMAN
NC score	0.062562 (rank : 290)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	156	Target Neighborhood Hits	715	Shared Neighborhood Hits	58
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LRP1B_HUMAN
NC score	0.062507 (rank : 291)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	156	Target Neighborhood Hits	602	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KRA45_HUMAN
NC score	0.062470 (rank : 292)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	156	Target Neighborhood Hits	194	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LAMB3_HUMAN
NC score	0.062168 (rank : 293)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	156	Target Neighborhood Hits	461	Shared Neighborhood Hits	51
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

FBLN3_MOUSE
NC score	0.062166 (rank : 294)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	156	Target Neighborhood Hits	279	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

EGF_HUMAN
NC score	0.062141 (rank : 295)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	156	Target Neighborhood Hits	343	Shared Neighborhood Hits	59
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

GAS6_HUMAN
NC score	0.061817 (rank : 296)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	156	Target Neighborhood Hits	348	Shared Neighborhood Hits	53
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITB1_HUMAN
NC score	0.061515 (rank : 297)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	156	Target Neighborhood Hits	298	Shared Neighborhood Hits	61
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KRA11_HUMAN
NC score	0.061398 (rank : 298)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	156	Target Neighborhood Hits	155	Shared Neighborhood Hits	35
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

MATN4_HUMAN
NC score	0.061345 (rank : 299)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	156	Target Neighborhood Hits	287	Shared Neighborhood Hits	50
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

EGFL8_HUMAN
NC score	0.061175 (rank : 300)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	156	Target Neighborhood Hits	270	Shared Neighborhood Hits	39
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

LRP1_HUMAN
NC score	0.061064 (rank : 301)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	156	Target Neighborhood Hits	617	Shared Neighborhood Hits	77
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_MOUSE
NC score	0.060958 (rank : 302)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	156	Target Neighborhood Hits	606	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EGFL7_MOUSE
NC score	0.060828 (rank : 303)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	156	Target Neighborhood Hits	287	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EDIL3_MOUSE
NC score	0.060657 (rank : 304)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	156	Target Neighborhood Hits	317	Shared Neighborhood Hits	47
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGF_MOUSE
NC score	0.060622 (rank : 305)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	156	Target Neighborhood Hits	358	Shared Neighborhood Hits	53
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

TSP3_MOUSE
NC score	0.060586 (rank : 306)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	156	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

THSD1_HUMAN
NC score	0.060406 (rank : 307)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	156	Target Neighborhood Hits	136	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TEFF2_MOUSE
NC score	0.059960 (rank : 308)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	156	Target Neighborhood Hits	214	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

LAMA3_HUMAN
NC score	0.059849 (rank : 309)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	156	Target Neighborhood Hits	760	Shared Neighborhood Hits	53
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LCE2A_HUMAN
NC score	0.059804 (rank : 310)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	156	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

NTNG2_MOUSE
NC score	0.059719 (rank : 311)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

KRA99_HUMAN
NC score	0.059681 (rank : 312)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	156	Target Neighborhood Hits	173	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

EGFL8_MOUSE
NC score	0.059348 (rank : 313)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	156	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

USH2A_MOUSE
NC score	0.059258 (rank : 314)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	156	Target Neighborhood Hits	626	Shared Neighborhood Hits	61
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

EMR1_MOUSE
NC score	0.059226 (rank : 315)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	156	Target Neighborhood Hits	349	Shared Neighborhood Hits	56
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

KRA15_HUMAN
NC score	0.059051 (rank : 316)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	156	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

HHIP_HUMAN
NC score	0.059035 (rank : 317)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	156	Target Neighborhood Hits	249	Shared Neighborhood Hits	49
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

CO2A1_MOUSE
NC score	0.058842 (rank : 318)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	156	Target Neighborhood Hits	483	Shared Neighborhood Hits	30
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

NTNG2_HUMAN
NC score	0.058641 (rank : 319)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TSP3_HUMAN
NC score	0.058503 (rank : 320)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	156	Target Neighborhood Hits	250	Shared Neighborhood Hits	46
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

ITB1_MOUSE
NC score	0.058212 (rank : 321)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	156	Target Neighborhood Hits	283	Shared Neighborhood Hits	63
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

THSD1_MOUSE
NC score	0.058009 (rank : 322)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	156	Target Neighborhood Hits	153	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TEFF2_HUMAN
NC score	0.057711 (rank : 323)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	156	Target Neighborhood Hits	211	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

ITB7_MOUSE
NC score	0.057587 (rank : 324)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	156	Target Neighborhood Hits	277	Shared Neighborhood Hits	54
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB2_HUMAN
NC score	0.057519 (rank : 325)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	156	Target Neighborhood Hits	282	Shared Neighborhood Hits	49
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB5_MOUSE
NC score	0.057351 (rank : 326)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	61
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

EDIL3_HUMAN
NC score	0.057141 (rank : 327)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	156	Target Neighborhood Hits	292	Shared Neighborhood Hits	44
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EMR2_HUMAN
NC score	0.057100 (rank : 328)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	156	Target Neighborhood Hits	345	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

PGBM_MOUSE
NC score	0.056911 (rank : 329)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	156	Target Neighborhood Hits	1073	Shared Neighborhood Hits	78
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

HHIP_MOUSE
NC score	0.056592 (rank : 330)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	156	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

CO5A2_HUMAN
NC score	0.056544 (rank : 331)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	156	Target Neighborhood Hits	760	Shared Neighborhood Hits	43
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CD97_HUMAN
NC score	0.056402 (rank : 332)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	156	Target Neighborhood Hits	353	Shared Neighborhood Hits	50
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

LCE3A_HUMAN
NC score	0.056371 (rank : 333)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	156	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

ITB6_MOUSE
NC score	0.055870 (rank : 334)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	156	Target Neighborhood Hits	341	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

PGBM_HUMAN
NC score	0.055796 (rank : 335)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	156	Target Neighborhood Hits	1113	Shared Neighborhood Hits	78
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

VEGFC_HUMAN
NC score	0.055565 (rank : 336)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	156	Target Neighborhood Hits	128	Shared Neighborhood Hits	39
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CO1A1_HUMAN
NC score	0.055496 (rank : 337)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	156	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SUSD1_HUMAN
NC score	0.055396 (rank : 338)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	156	Target Neighborhood Hits	285	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

NTNG1_HUMAN
NC score	0.055355 (rank : 339)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	156	Target Neighborhood Hits	247	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ITB3_MOUSE
NC score	0.055255 (rank : 340)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	156	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LAMA4_MOUSE
NC score	0.054952 (rank : 341)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	156	Target Neighborhood Hits	584	Shared Neighborhood Hits	54
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KRA44_HUMAN
NC score	0.054846 (rank : 342)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	156	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

ITB5_HUMAN
NC score	0.054657 (rank : 343)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	63
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB3_HUMAN
NC score	0.054343 (rank : 344)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	156	Target Neighborhood Hits	325	Shared Neighborhood Hits	62
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ADA23_MOUSE
NC score	0.054312 (rank : 345)	θ value	0.813845 (rank : 82)
Query Neighborhood Hits	156	Target Neighborhood Hits	245	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ITB6_HUMAN
NC score	0.054233 (rank : 346)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	156	Target Neighborhood Hits	318	Shared Neighborhood Hits	62
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ADA17_HUMAN
NC score	0.054113 (rank : 347)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	156	Target Neighborhood Hits	223	Shared Neighborhood Hits	58
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

KR410_HUMAN
NC score	0.054080 (rank : 348)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	156	Target Neighborhood Hits	156	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

USH2A_HUMAN
NC score	0.054060 (rank : 349)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	156	Target Neighborhood Hits	600	Shared Neighborhood Hits	60
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

IBP6_MOUSE
NC score	0.053913 (rank : 350)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	156	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

NTNG1_MOUSE
NC score	0.053871 (rank : 351)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	156	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

MATN4_MOUSE
NC score	0.053857 (rank : 352)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	156	Target Neighborhood Hits	277	Shared Neighborhood Hits	41
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

KRA94_HUMAN
NC score	0.053136 (rank : 353)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	156	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

CO8B_MOUSE
NC score	0.053078 (rank : 354)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	156	Target Neighborhood Hits	224	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

MATN3_MOUSE
NC score	0.052245 (rank : 355)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	156	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LAMA4_HUMAN
NC score	0.051815 (rank : 356)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	156	Target Neighborhood Hits	708	Shared Neighborhood Hits	52
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

IBP6_HUMAN
NC score	0.051709 (rank : 357)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	156	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

ADA23_HUMAN
NC score	0.051578 (rank : 358)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	156	Target Neighborhood Hits	235	Shared Neighborhood Hits	69
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADAM9_MOUSE
NC score	0.051444 (rank : 359)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	156	Target Neighborhood Hits	325	Shared Neighborhood Hits	73
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

LDLR_HUMAN
NC score	0.051346 (rank : 360)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	156	Target Neighborhood Hits	375	Shared Neighborhood Hits	60
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CO7_HUMAN
NC score	0.051272 (rank : 361)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	156	Target Neighborhood Hits	278	Shared Neighborhood Hits	57
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

MATN3_HUMAN
NC score	0.051271 (rank : 362)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	156	Target Neighborhood Hits	268	Shared Neighborhood Hits	44
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

NDP_MOUSE
NC score	0.051125 (rank : 363)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	156	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P48744	Gene names	Ndp, Ndph
Domain Architecture
Description	Norrin precursor (Norrie disease protein homolog).

ADAM8_MOUSE
NC score	0.050662 (rank : 364)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	156	Target Neighborhood Hits	326	Shared Neighborhood Hits	65
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

LRP2_HUMAN
NC score	0.050485 (rank : 365)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	156	Target Neighborhood Hits	573	Shared Neighborhood Hits	75
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

CO3A1_MOUSE
NC score	0.050392 (rank : 366)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	156	Target Neighborhood Hits	466	Shared Neighborhood Hits	31
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

ADA17_MOUSE
NC score	0.050369 (rank : 367)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	156	Target Neighborhood Hits	201	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

CO3A1_HUMAN
NC score	0.050001 (rank : 368)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	156	Target Neighborhood Hits	452	Shared Neighborhood Hits	33
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

TNR9_HUMAN
NC score	0.049428 (rank : 369)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	156	Target Neighborhood Hits	166	Shared Neighborhood Hits	30
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

NDP_HUMAN
NC score	0.046912 (rank : 370)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	156	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q00604	Gene names	NDP
Domain Architecture
Description	Norrin precursor (Norrie disease protein).

ADA32_HUMAN
NC score	0.045582 (rank : 371)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	156	Target Neighborhood Hits	216	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

VEGFC_MOUSE
NC score	0.043275 (rank : 372)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	156	Target Neighborhood Hits	119	Shared Neighborhood Hits	35
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADAM2_MOUSE
NC score	0.040899 (rank : 373)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	156	Target Neighborhood Hits	209	Shared Neighborhood Hits	58
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

TIF1G_HUMAN
NC score	0.012333 (rank : 374)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	156	Target Neighborhood Hits	410	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.010899 (rank : 375)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	156	Target Neighborhood Hits	498	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

CO4A_HUMAN
NC score	0.008530 (rank : 376)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	156	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

CO4B_HUMAN
NC score	0.008525 (rank : 377)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	156	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

ANK3_HUMAN
NC score	0.005362 (rank : 378)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	156	Target Neighborhood Hits	853	Shared Neighborhood Hits	13
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

RECQ5_HUMAN
NC score	0.004915 (rank : 379)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	156	Target Neighborhood Hits	390	Shared Neighborhood Hits	5
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

ZNF77_HUMAN
NC score	-0.001777 (rank : 380)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	156	Target Neighborhood Hits	759	Shared Neighborhood Hits	10
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).

ZN491_HUMAN
NC score	-0.004071 (rank : 381)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	156	Target Neighborhood Hits	734	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N8L2, Q8NAT8	Gene names	ZNF491
Domain Architecture	No domain graphic available
Description	Zinc finger protein 491.