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Network neighborhood for query Sequence : ATS20_HUMAN

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ATS20_HUMAN
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATS15_HUMAN
θ value	0 (rank : 1)	NC score	0.979700 (rank : 4)
Query Neighborhood Hits	192	Target Neighborhood Hits	151	Shared Neighborhood Hits	133
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS1_MOUSE
θ value	0 (rank : 2)	NC score	0.977422 (rank : 5)
Query Neighborhood Hits	192	Target Neighborhood Hits	158	Shared Neighborhood Hits	134
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS20_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	192	Target Neighborhood Hits	192	Shared Neighborhood Hits	192
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	0 (rank : 4)	NC score	0.994178 (rank : 2)
Query Neighborhood Hits	192	Target Neighborhood Hits	225	Shared Neighborhood Hits	150
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS9_HUMAN
θ value	0 (rank : 5)	NC score	0.989810 (rank : 3)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	151
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS1_HUMAN
θ value	7.22167e-183 (rank : 6)	NC score	0.976238 (rank : 6)
Query Neighborhood Hits	192	Target Neighborhood Hits	159	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS8_MOUSE
θ value	5.01279e-176 (rank : 7)	NC score	0.967752 (rank : 18)
Query Neighborhood Hits	192	Target Neighborhood Hits	139	Shared Neighborhood Hits	122
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS8_HUMAN
θ value	6.12769e-174 (rank : 8)	NC score	0.973205 (rank : 8)
Query Neighborhood Hits	192	Target Neighborhood Hits	145	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS5_HUMAN
θ value	4.26331e-159 (rank : 9)	NC score	0.971132 (rank : 12)
Query Neighborhood Hits	192	Target Neighborhood Hits	141	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS5_MOUSE
θ value	1.62005e-158 (rank : 10)	NC score	0.973916 (rank : 7)
Query Neighborhood Hits	192	Target Neighborhood Hits	147	Shared Neighborhood Hits	124
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS4_MOUSE
θ value	8.04023e-158 (rank : 11)	NC score	0.959289 (rank : 23)
Query Neighborhood Hits	192	Target Neighborhood Hits	145	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS18_HUMAN
θ value	1.05009e-157 (rank : 12)	NC score	0.971798 (rank : 9)
Query Neighborhood Hits	192	Target Neighborhood Hits	169	Shared Neighborhood Hits	131
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
θ value	6.80647e-157 (rank : 13)	NC score	0.971178 (rank : 11)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	131
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS4_HUMAN
θ value	1.98038e-156 (rank : 14)	NC score	0.957573 (rank : 26)
Query Neighborhood Hits	192	Target Neighborhood Hits	138	Shared Neighborhood Hits	113
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS12_HUMAN
θ value	7.28896e-151 (rank : 15)	NC score	0.968633 (rank : 16)
Query Neighborhood Hits	192	Target Neighborhood Hits	251	Shared Neighborhood Hits	135
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_MOUSE
θ value	1.37464e-149 (rank : 16)	NC score	0.969736 (rank : 14)
Query Neighborhood Hits	192	Target Neighborhood Hits	220	Shared Neighborhood Hits	135
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS16_MOUSE
θ value	1.37464e-149 (rank : 17)	NC score	0.969840 (rank : 13)
Query Neighborhood Hits	192	Target Neighborhood Hits	179	Shared Neighborhood Hits	139
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_HUMAN
θ value	4.73554e-142 (rank : 18)	NC score	0.968254 (rank : 17)
Query Neighborhood Hits	192	Target Neighborhood Hits	208	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS19_MOUSE
θ value	1.74701e-128 (rank : 19)	NC score	0.959326 (rank : 22)
Query Neighborhood Hits	192	Target Neighborhood Hits	188	Shared Neighborhood Hits	131
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS7_HUMAN
θ value	5.08302e-128 (rank : 20)	NC score	0.971207 (rank : 10)
Query Neighborhood Hits	192	Target Neighborhood Hits	169	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS19_HUMAN
θ value	1.25199e-126 (rank : 21)	NC score	0.958453 (rank : 25)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	129
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS2_HUMAN
θ value	1.63515e-126 (rank : 22)	NC score	0.960374 (rank : 21)
Query Neighborhood Hits	192	Target Neighborhood Hits	179	Shared Neighborhood Hits	132
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS17_HUMAN
θ value	2.78914e-126 (rank : 23)	NC score	0.966746 (rank : 19)
Query Neighborhood Hits	192	Target Neighborhood Hits	194	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS6_HUMAN
θ value	3.08376e-125 (rank : 24)	NC score	0.969471 (rank : 15)
Query Neighborhood Hits	192	Target Neighborhood Hits	141	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS2_MOUSE
θ value	8.97236e-125 (rank : 25)	NC score	0.959082 (rank : 24)
Query Neighborhood Hits	192	Target Neighborhood Hits	179	Shared Neighborhood Hits	126
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	1.29561e-123 (rank : 26)	NC score	0.964614 (rank : 20)
Query Neighborhood Hits	192	Target Neighborhood Hits	179	Shared Neighborhood Hits	138
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS14_HUMAN
θ value	1.53401e-116 (rank : 27)	NC score	0.954221 (rank : 27)
Query Neighborhood Hits	192	Target Neighborhood Hits	382	Shared Neighborhood Hits	128
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS13_HUMAN
θ value	4.32305e-111 (rank : 28)	NC score	0.924662 (rank : 28)
Query Neighborhood Hits	192	Target Neighborhood Hits	238	Shared Neighborhood Hits	126
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL3_HUMAN
θ value	7.44272e-79 (rank : 29)	NC score	0.748513 (rank : 35)
Query Neighborhood Hits	192	Target Neighborhood Hits	414	Shared Neighborhood Hits	99
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATL1_HUMAN
θ value	1.51013e-55 (rank : 30)	NC score	0.879903 (rank : 31)
Query Neighborhood Hits	192	Target Neighborhood Hits	93	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL2_MOUSE
θ value	5.95217e-44 (rank : 31)	NC score	0.850417 (rank : 33)
Query Neighborhood Hits	192	Target Neighborhood Hits	137	Shared Neighborhood Hits	92
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL2_HUMAN
θ value	2.26182e-43 (rank : 32)	NC score	0.849382 (rank : 34)
Query Neighborhood Hits	192	Target Neighborhood Hits	125	Shared Neighborhood Hits	91
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATS13_MOUSE
θ value	4.41421e-39 (rank : 33)	NC score	0.915596 (rank : 29)
Query Neighborhood Hits	192	Target Neighborhood Hits	227	Shared Neighborhood Hits	128
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL5_HUMAN
θ value	1.42001e-37 (rank : 34)	NC score	0.881276 (rank : 30)
Query Neighborhood Hits	192	Target Neighborhood Hits	103	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL1_MOUSE
θ value	3.16345e-37 (rank : 35)	NC score	0.871683 (rank : 32)
Query Neighborhood Hits	192	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ADA28_MOUSE
θ value	1.08979e-29 (rank : 36)	NC score	0.611157 (rank : 39)
Query Neighborhood Hits	192	Target Neighborhood Hits	241	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADAM8_HUMAN
θ value	2.05525e-28 (rank : 37)	NC score	0.613635 (rank : 38)
Query Neighborhood Hits	192	Target Neighborhood Hits	327	Shared Neighborhood Hits	100
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CI094_HUMAN
θ value	4.28545e-26 (rank : 38)	NC score	0.563477 (rank : 55)
Query Neighborhood Hits	192	Target Neighborhood Hits	310	Shared Neighborhood Hits	74
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ADA28_HUMAN
θ value	1.62847e-25 (rank : 39)	NC score	0.601888 (rank : 42)
Query Neighborhood Hits	192	Target Neighborhood Hits	244	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA23_MOUSE
θ value	3.39556e-23 (rank : 40)	NC score	0.531406 (rank : 61)
Query Neighborhood Hits	192	Target Neighborhood Hits	245	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADAM7_HUMAN
θ value	9.87957e-23 (rank : 41)	NC score	0.576591 (rank : 50)
Query Neighborhood Hits	192	Target Neighborhood Hits	221	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM8_MOUSE
θ value	1.29031e-22 (rank : 42)	NC score	0.609182 (rank : 40)
Query Neighborhood Hits	192	Target Neighborhood Hits	326	Shared Neighborhood Hits	104
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADA23_HUMAN
θ value	1.6852e-22 (rank : 43)	NC score	0.524526 (rank : 65)
Query Neighborhood Hits	192	Target Neighborhood Hits	235	Shared Neighborhood Hits	99
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA19_HUMAN
θ value	2.20094e-22 (rank : 44)	NC score	0.599249 (rank : 43)
Query Neighborhood Hits	192	Target Neighborhood Hits	381	Shared Neighborhood Hits	101
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	3.75424e-22 (rank : 45)	NC score	0.607646 (rank : 41)
Query Neighborhood Hits	192	Target Neighborhood Hits	315	Shared Neighborhood Hits	104
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

HMCN1_HUMAN
θ value	6.40375e-22 (rank : 46)	NC score	0.294605 (rank : 118)
Query Neighborhood Hits	192	Target Neighborhood Hits	983	Shared Neighborhood Hits	137
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ADA33_HUMAN
θ value	1.86321e-21 (rank : 47)	NC score	0.593343 (rank : 45)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM7_MOUSE
θ value	1.86321e-21 (rank : 48)	NC score	0.573596 (rank : 51)
Query Neighborhood Hits	192	Target Neighborhood Hits	200	Shared Neighborhood Hits	90
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

SSPO_MOUSE
θ value	3.17815e-21 (rank : 49)	NC score	0.442263 (rank : 93)
Query Neighborhood Hits	192	Target Neighborhood Hits	800	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ADA33_MOUSE
θ value	1.2077e-20 (rank : 50)	NC score	0.567556 (rank : 53)
Query Neighborhood Hits	192	Target Neighborhood Hits	231	Shared Neighborhood Hits	94
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA12_HUMAN
θ value	1.33526e-19 (rank : 51)	NC score	0.592412 (rank : 47)
Query Neighborhood Hits	192	Target Neighborhood Hits	224	Shared Neighborhood Hits	95
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM9_HUMAN
θ value	5.07402e-19 (rank : 52)	NC score	0.560037 (rank : 56)
Query Neighborhood Hits	192	Target Neighborhood Hits	243	Shared Neighborhood Hits	100
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADA22_MOUSE
θ value	3.28887e-18 (rank : 53)	NC score	0.527395 (rank : 64)
Query Neighborhood Hits	192	Target Neighborhood Hits	225	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADAM9_MOUSE
θ value	5.60996e-18 (rank : 54)	NC score	0.569554 (rank : 52)
Query Neighborhood Hits	192	Target Neighborhood Hits	325	Shared Neighborhood Hits	104
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

SEM5B_HUMAN
θ value	1.63225e-17 (rank : 55)	NC score	0.424690 (rank : 104)
Query Neighborhood Hits	192	Target Neighborhood Hits	178	Shared Neighborhood Hits	92
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ADA21_HUMAN
θ value	4.74913e-17 (rank : 56)	NC score	0.514153 (rank : 67)
Query Neighborhood Hits	192	Target Neighborhood Hits	181	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA22_HUMAN
θ value	1.058e-16 (rank : 57)	NC score	0.538210 (rank : 58)
Query Neighborhood Hits	192	Target Neighborhood Hits	211	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

BAI1_HUMAN
θ value	1.38178e-16 (rank : 58)	NC score	0.468915 (rank : 81)
Query Neighborhood Hits	192	Target Neighborhood Hits	375	Shared Neighborhood Hits	99
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ADA12_MOUSE
θ value	1.80466e-16 (rank : 59)	NC score	0.582191 (rank : 49)
Query Neighborhood Hits	192	Target Neighborhood Hits	474	Shared Neighborhood Hits	100
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

SEM5B_MOUSE
θ value	2.35696e-16 (rank : 60)	NC score	0.425861 (rank : 102)
Query Neighborhood Hits	192	Target Neighborhood Hits	190	Shared Neighborhood Hits	94
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

ADA21_MOUSE
θ value	8.95645e-16 (rank : 61)	NC score	0.529286 (rank : 62)
Query Neighborhood Hits	192	Target Neighborhood Hits	172	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

BAI1_MOUSE
θ value	1.52774e-15 (rank : 62)	NC score	0.470396 (rank : 79)
Query Neighborhood Hits	192	Target Neighborhood Hits	340	Shared Neighborhood Hits	94
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_MOUSE
θ value	1.99529e-15 (rank : 63)	NC score	0.465606 (rank : 86)
Query Neighborhood Hits	192	Target Neighborhood Hits	250	Shared Neighborhood Hits	97
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

SEM5A_HUMAN
θ value	1.99529e-15 (rank : 64)	NC score	0.436124 (rank : 97)
Query Neighborhood Hits	192	Target Neighborhood Hits	177	Shared Neighborhood Hits	93
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

BAI3_HUMAN
θ value	3.40345e-15 (rank : 65)	NC score	0.465455 (rank : 87)
Query Neighborhood Hits	192	Target Neighborhood Hits	246	Shared Neighborhood Hits	92
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TSP2_HUMAN
θ value	3.40345e-15 (rank : 66)	NC score	0.464957 (rank : 89)
Query Neighborhood Hits	192	Target Neighborhood Hits	359	Shared Neighborhood Hits	116
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

PROP_MOUSE
θ value	4.44505e-15 (rank : 67)	NC score	0.638147 (rank : 37)
Query Neighborhood Hits	192	Target Neighborhood Hits	165	Shared Neighborhood Hits	92
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SPON1_HUMAN
θ value	4.44505e-15 (rank : 68)	NC score	0.593102 (rank : 46)
Query Neighborhood Hits	192	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	4.44505e-15 (rank : 69)	NC score	0.591788 (rank : 48)
Query Neighborhood Hits	192	Target Neighborhood Hits	123	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

PROP_HUMAN
θ value	1.29331e-14 (rank : 70)	NC score	0.643752 (rank : 36)
Query Neighborhood Hits	192	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

BAI2_HUMAN
θ value	1.68911e-14 (rank : 71)	NC score	0.468123 (rank : 82)
Query Neighborhood Hits	192	Target Neighborhood Hits	332	Shared Neighborhood Hits	96
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

SEM5A_MOUSE
θ value	1.68911e-14 (rank : 72)	NC score	0.426707 (rank : 101)
Query Neighborhood Hits	192	Target Neighborhood Hits	162	Shared Neighborhood Hits	90
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ADA15_HUMAN
θ value	2.88119e-14 (rank : 73)	NC score	0.566798 (rank : 54)
Query Neighborhood Hits	192	Target Neighborhood Hits	288	Shared Neighborhood Hits	100
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

BAI2_MOUSE
θ value	2.88119e-14 (rank : 74)	NC score	0.465918 (rank : 85)
Query Neighborhood Hits	192	Target Neighborhood Hits	323	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TSP1_HUMAN
θ value	2.88119e-14 (rank : 75)	NC score	0.472167 (rank : 75)
Query Neighborhood Hits	192	Target Neighborhood Hits	389	Shared Neighborhood Hits	119
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	2.88119e-14 (rank : 76)	NC score	0.471766 (rank : 76)
Query Neighborhood Hits	192	Target Neighborhood Hits	396	Shared Neighborhood Hits	121
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADM1A_MOUSE
θ value	4.91457e-14 (rank : 77)	NC score	0.527679 (rank : 63)
Query Neighborhood Hits	192	Target Neighborhood Hits	230	Shared Neighborhood Hits	96
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

TSP2_MOUSE
θ value	4.91457e-14 (rank : 78)	NC score	0.467570 (rank : 83)
Query Neighborhood Hits	192	Target Neighborhood Hits	352	Shared Neighborhood Hits	115
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADEC1_HUMAN
θ value	1.42992e-13 (rank : 79)	NC score	0.593937 (rank : 44)
Query Neighborhood Hits	192	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA25_MOUSE
θ value	4.16044e-13 (rank : 80)	NC score	0.513777 (rank : 68)
Query Neighborhood Hits	192	Target Neighborhood Hits	213	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

AD26A_MOUSE
θ value	2.69671e-12 (rank : 81)	NC score	0.510210 (rank : 70)
Query Neighborhood Hits	192	Target Neighborhood Hits	165	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADM1B_MOUSE
θ value	2.69671e-12 (rank : 82)	NC score	0.534507 (rank : 60)
Query Neighborhood Hits	192	Target Neighborhood Hits	236	Shared Neighborhood Hits	98
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA15_MOUSE
θ value	2.28291e-11 (rank : 83)	NC score	0.536766 (rank : 59)
Query Neighborhood Hits	192	Target Neighborhood Hits	324	Shared Neighborhood Hits	103
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA11_MOUSE
θ value	6.64225e-11 (rank : 84)	NC score	0.510092 (rank : 71)
Query Neighborhood Hits	192	Target Neighborhood Hits	263	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA32_MOUSE
θ value	3.29651e-10 (rank : 85)	NC score	0.465241 (rank : 88)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA11_HUMAN
θ value	5.62301e-10 (rank : 86)	NC score	0.487284 (rank : 73)
Query Neighborhood Hits	192	Target Neighborhood Hits	259	Shared Neighborhood Hits	96
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA32_HUMAN
θ value	7.34386e-10 (rank : 87)	NC score	0.469347 (rank : 80)
Query Neighborhood Hits	192	Target Neighborhood Hits	216	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA24_MOUSE
θ value	1.63604e-09 (rank : 88)	NC score	0.521705 (rank : 66)
Query Neighborhood Hits	192	Target Neighborhood Hits	230	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA29_HUMAN
θ value	2.13673e-09 (rank : 89)	NC score	0.513722 (rank : 69)
Query Neighborhood Hits	192	Target Neighborhood Hits	247	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

CO8A_HUMAN
θ value	2.13673e-09 (rank : 90)	NC score	0.429645 (rank : 99)
Query Neighborhood Hits	192	Target Neighborhood Hits	200	Shared Neighborhood Hits	83
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

UNC5A_MOUSE
θ value	1.06045e-08 (rank : 91)	NC score	0.466974 (rank : 84)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	1.06045e-08 (rank : 92)	NC score	0.453600 (rank : 91)
Query Neighborhood Hits	192	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	1.06045e-08 (rank : 93)	NC score	0.455927 (rank : 90)
Query Neighborhood Hits	192	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	3.08544e-08 (rank : 94)	NC score	0.439631 (rank : 95)
Query Neighborhood Hits	192	Target Neighborhood Hits	226	Shared Neighborhood Hits	76
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	3.08544e-08 (rank : 95)	NC score	0.440162 (rank : 94)
Query Neighborhood Hits	192	Target Neighborhood Hits	225	Shared Neighborhood Hits	76
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

ADAM2_HUMAN
θ value	5.26297e-08 (rank : 96)	NC score	0.438894 (rank : 96)
Query Neighborhood Hits	192	Target Neighborhood Hits	175	Shared Neighborhood Hits	81
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADEC1_MOUSE
θ value	6.87365e-08 (rank : 97)	NC score	0.543886 (rank : 57)
Query Neighborhood Hits	192	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

CO8A_MOUSE
θ value	1.99992e-07 (rank : 98)	NC score	0.420524 (rank : 105)
Query Neighborhood Hits	192	Target Neighborhood Hits	182	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

UNC5D_HUMAN
θ value	1.99992e-07 (rank : 99)	NC score	0.431152 (rank : 98)
Query Neighborhood Hits	192	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ADAM2_MOUSE
θ value	3.41135e-07 (rank : 100)	NC score	0.475038 (rank : 74)
Query Neighborhood Hits	192	Target Neighborhood Hits	209	Shared Neighborhood Hits	94
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

UNC5D_MOUSE
θ value	3.41135e-07 (rank : 101)	NC score	0.427643 (rank : 100)
Query Neighborhood Hits	192	Target Neighborhood Hits	268	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5A_HUMAN
θ value	4.45536e-07 (rank : 102)	NC score	0.381578 (rank : 114)
Query Neighborhood Hits	192	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ADA18_HUMAN
θ value	7.59969e-07 (rank : 103)	NC score	0.425805 (rank : 103)
Query Neighborhood Hits	192	Target Neighborhood Hits	184	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA20_HUMAN
θ value	2.21117e-06 (rank : 104)	NC score	0.470877 (rank : 78)
Query Neighborhood Hits	192	Target Neighborhood Hits	143	Shared Neighborhood Hits	85
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA30_HUMAN
θ value	2.88788e-06 (rank : 105)	NC score	0.416931 (rank : 107)
Query Neighborhood Hits	192	Target Neighborhood Hits	391	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CILP2_HUMAN
θ value	3.77169e-06 (rank : 106)	NC score	0.398713 (rank : 112)
Query Neighborhood Hits	192	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CO6_HUMAN
θ value	1.09739e-05 (rank : 107)	NC score	0.417684 (rank : 106)
Query Neighborhood Hits	192	Target Neighborhood Hits	331	Shared Neighborhood Hits	102
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ADA17_MOUSE
θ value	2.44474e-05 (rank : 108)	NC score	0.407667 (rank : 108)
Query Neighborhood Hits	192	Target Neighborhood Hits	201	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

CO8B_HUMAN
θ value	2.44474e-05 (rank : 109)	NC score	0.365881 (rank : 116)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	79
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	7.1131e-05 (rank : 110)	NC score	0.402281 (rank : 109)
Query Neighborhood Hits	192	Target Neighborhood Hits	224	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

FRAS1_MOUSE
θ value	7.1131e-05 (rank : 111)	NC score	0.115974 (rank : 125)
Query Neighborhood Hits	192	Target Neighborhood Hits	747	Shared Neighborhood Hits	120
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CILP1_HUMAN
θ value	0.000121331 (rank : 112)	NC score	0.294815 (rank : 117)
Query Neighborhood Hits	192	Target Neighborhood Hits	266	Shared Neighborhood Hits	81
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

THSD1_HUMAN
θ value	0.00020696 (rank : 113)	NC score	0.501315 (rank : 72)
Query Neighborhood Hits	192	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CO7_HUMAN
θ value	0.000270298 (rank : 114)	NC score	0.369965 (rank : 115)
Query Neighborhood Hits	192	Target Neighborhood Hits	278	Shared Neighborhood Hits	90
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

THSD1_MOUSE
θ value	0.00035302 (rank : 115)	NC score	0.471371 (rank : 77)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA18_MOUSE
θ value	0.000461057 (rank : 116)	NC score	0.448412 (rank : 92)
Query Neighborhood Hits	192	Target Neighborhood Hits	227	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA17_HUMAN
θ value	0.00175202 (rank : 117)	NC score	0.395962 (rank : 113)
Query Neighborhood Hits	192	Target Neighborhood Hits	223	Shared Neighborhood Hits	92
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

FRAS1_HUMAN
θ value	0.00509761 (rank : 118)	NC score	0.101640 (rank : 134)
Query Neighborhood Hits	192	Target Neighborhood Hits	759	Shared Neighborhood Hits	116
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CILP1_MOUSE
θ value	0.00869519 (rank : 119)	NC score	0.289055 (rank : 119)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

TENA_MOUSE
θ value	0.0193708 (rank : 120)	NC score	0.064581 (rank : 164)
Query Neighborhood Hits	192	Target Neighborhood Hits	596	Shared Neighborhood Hits	84
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

WISP2_MOUSE
θ value	0.0252991 (rank : 121)	NC score	0.159730 (rank : 120)
Query Neighborhood Hits	192	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

LRP2_HUMAN
θ value	0.0431538 (rank : 122)	NC score	0.066616 (rank : 161)
Query Neighborhood Hits	192	Target Neighborhood Hits	573	Shared Neighborhood Hits	93
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

WISP2_HUMAN
θ value	0.0961366 (rank : 123)	NC score	0.159440 (rank : 121)
Query Neighborhood Hits	192	Target Neighborhood Hits	126	Shared Neighborhood Hits	64
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

AGRIN_HUMAN
θ value	0.125558 (rank : 124)	NC score	0.046018 (rank : 208)
Query Neighborhood Hits	192	Target Neighborhood Hits	582	Shared Neighborhood Hits	77
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

RXINP_MOUSE
θ value	0.125558 (rank : 125)	NC score	0.020595 (rank : 219)
Query Neighborhood Hits	192	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

TENA_HUMAN
θ value	0.125558 (rank : 126)	NC score	0.058737 (rank : 174)
Query Neighborhood Hits	192	Target Neighborhood Hits	631	Shared Neighborhood Hits	87
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LRP1_HUMAN
θ value	0.279714 (rank : 127)	NC score	0.064515 (rank : 165)
Query Neighborhood Hits	192	Target Neighborhood Hits	617	Shared Neighborhood Hits	99
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

WISP1_MOUSE
θ value	0.279714 (rank : 128)	NC score	0.137350 (rank : 122)
Query Neighborhood Hits	192	Target Neighborhood Hits	123	Shared Neighborhood Hits	65
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

NOV_MOUSE
θ value	0.365318 (rank : 129)	NC score	0.114410 (rank : 126)
Query Neighborhood Hits	192	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

APOA_HUMAN
θ value	0.47712 (rank : 130)	NC score	0.004233 (rank : 236)
Query Neighborhood Hits	192	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

LRP1B_MOUSE
θ value	0.47712 (rank : 131)	NC score	0.062485 (rank : 166)
Query Neighborhood Hits	192	Target Neighborhood Hits	606	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ADA10_MOUSE
θ value	0.62314 (rank : 132)	NC score	0.402000 (rank : 110)
Query Neighborhood Hits	192	Target Neighborhood Hits	194	Shared Neighborhood Hits	88
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

LAMA5_HUMAN
θ value	0.62314 (rank : 133)	NC score	0.022970 (rank : 218)
Query Neighborhood Hits	192	Target Neighborhood Hits	976	Shared Neighborhood Hits	70
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

RSPO4_HUMAN
θ value	0.62314 (rank : 134)	NC score	0.084488 (rank : 141)
Query Neighborhood Hits	192	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

ADA10_HUMAN
θ value	0.813845 (rank : 135)	NC score	0.399882 (rank : 111)
Query Neighborhood Hits	192	Target Neighborhood Hits	189	Shared Neighborhood Hits	89
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

MMP12_MOUSE
θ value	0.813845 (rank : 136)	NC score	0.010997 (rank : 225)
Query Neighborhood Hits	192	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

RSPO3_HUMAN
θ value	0.813845 (rank : 137)	NC score	0.079454 (rank : 147)
Query Neighborhood Hits	192	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

CYR61_HUMAN
θ value	1.06291 (rank : 138)	NC score	0.122027 (rank : 124)
Query Neighborhood Hits	192	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

HPS4_MOUSE
θ value	1.06291 (rank : 139)	NC score	0.013567 (rank : 223)
Query Neighborhood Hits	192	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

LTBP4_MOUSE
θ value	1.06291 (rank : 140)	NC score	0.041488 (rank : 212)
Query Neighborhood Hits	192	Target Neighborhood Hits	607	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LRP1B_HUMAN
θ value	1.38821 (rank : 141)	NC score	0.066686 (rank : 160)
Query Neighborhood Hits	192	Target Neighborhood Hits	602	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MEGF8_HUMAN
θ value	1.38821 (rank : 142)	NC score	0.034863 (rank : 213)
Query Neighborhood Hits	192	Target Neighborhood Hits	528	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MMP15_MOUSE
θ value	1.38821 (rank : 143)	NC score	0.010131 (rank : 227)
Query Neighborhood Hits	192	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

RSPO2_MOUSE
θ value	1.38821 (rank : 144)	NC score	0.061440 (rank : 170)
Query Neighborhood Hits	192	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

CYR61_MOUSE
θ value	1.81305 (rank : 145)	NC score	0.107413 (rank : 128)
Query Neighborhood Hits	192	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

LYAM3_HUMAN
θ value	1.81305 (rank : 146)	NC score	0.015479 (rank : 221)
Query Neighborhood Hits	192	Target Neighborhood Hits	378	Shared Neighborhood Hits	39
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

NFX1_HUMAN
θ value	1.81305 (rank : 147)	NC score	0.068939 (rank : 158)
Query Neighborhood Hits	192	Target Neighborhood Hits	405	Shared Neighborhood Hits	54
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

SREC2_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.052417 (rank : 197)
Query Neighborhood Hits	192	Target Neighborhood Hits	645	Shared Neighborhood Hits	77
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

CHRD_MOUSE
θ value	2.36792 (rank : 149)	NC score	0.027711 (rank : 216)
Query Neighborhood Hits	192	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

GLCM_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.009900 (rank : 228)
Query Neighborhood Hits	192	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P04062, Q16545, Q9UMJ8	Gene names	GBA, GC
Domain Architecture
Description	Glucosylceramidase precursor (EC 3.2.1.45) (Beta-glucocerebrosidase) (Acid beta-glucosidase) (D-glucosyl-N-acylsphingosine glucohydrolase) (Alglucerase) (Imiglucerase).

MPRI_MOUSE
θ value	2.36792 (rank : 151)	NC score	0.008420 (rank : 231)
Query Neighborhood Hits	192	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

NAGPA_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.044097 (rank : 211)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

PCSK5_MOUSE
θ value	2.36792 (rank : 153)	NC score	0.062065 (rank : 167)
Query Neighborhood Hits	192	Target Neighborhood Hits	613	Shared Neighborhood Hits	89
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

RSPO1_MOUSE
θ value	2.36792 (rank : 154)	NC score	0.091756 (rank : 136)
Query Neighborhood Hits	192	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

SLIT3_HUMAN
θ value	2.36792 (rank : 155)	NC score	0.018558 (rank : 220)
Query Neighborhood Hits	192	Target Neighborhood Hits	682	Shared Neighborhood Hits	59
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SPRE1_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.005718 (rank : 234)
Query Neighborhood Hits	192	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

SREC2_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.055994 (rank : 182)
Query Neighborhood Hits	192	Target Neighborhood Hits	605	Shared Neighborhood Hits	80
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CRIS2_HUMAN
θ value	3.0926 (rank : 158)	NC score	0.005700 (rank : 235)
Query Neighborhood Hits	192	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P16562	Gene names	CRISP2, TPX1
Domain Architecture
Description	Cysteine-rich secretory protein 2 precursor (CRISP-2) (Testis-specific protein TPX-1).

LTBP3_MOUSE
θ value	3.0926 (rank : 159)	NC score	0.045217 (rank : 209)
Query Neighborhood Hits	192	Target Neighborhood Hits	475	Shared Neighborhood Hits	78
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

RSPO1_HUMAN
θ value	3.0926 (rank : 160)	NC score	0.102889 (rank : 131)
Query Neighborhood Hits	192	Target Neighborhood Hits	101	Shared Neighborhood Hits	53
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO2_HUMAN
θ value	3.0926 (rank : 161)	NC score	0.066788 (rank : 159)
Query Neighborhood Hits	192	Target Neighborhood Hits	90	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

ABCA9_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.000148 (rank : 241)
Query Neighborhood Hits	192	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

JAG1_MOUSE
θ value	4.03905 (rank : 163)	NC score	0.053232 (rank : 193)
Query Neighborhood Hits	192	Target Neighborhood Hits	518	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

MMP13_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.014635 (rank : 222)
Query Neighborhood Hits	192	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

MMP28_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.012073 (rank : 224)
Query Neighborhood Hits	192	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

RSPO3_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.072292 (rank : 155)
Query Neighborhood Hits	192	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

TENX_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.080354 (rank : 146)
Query Neighborhood Hits	192	Target Neighborhood Hits	789	Shared Neighborhood Hits	103
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

WISP3_HUMAN
θ value	4.03905 (rank : 168)	NC score	0.110104 (rank : 127)
Query Neighborhood Hits	192	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

GRN_MOUSE
θ value	5.27518 (rank : 169)	NC score	0.029187 (rank : 215)
Query Neighborhood Hits	192	Target Neighborhood Hits	248	Shared Neighborhood Hits	45
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

MEGF6_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.064704 (rank : 163)
Query Neighborhood Hits	192	Target Neighborhood Hits	671	Shared Neighborhood Hits	116
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

ZN214_HUMAN
θ value	5.27518 (rank : 171)	NC score	-0.008367 (rank : 243)
Query Neighborhood Hits	192	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UL59	Gene names	ZNF214, BAZ1
Domain Architecture
Description	Zinc finger protein 214 (BWSCR2-associated zinc-finger protein 1) (BAZ 1).

ACCN2_HUMAN
θ value	6.88961 (rank : 172)	NC score	0.002855 (rank : 237)
Query Neighborhood Hits	192	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P78348, P78349, Q96CV2	Gene names	ACCN2, ASIC1, BNAC2
Domain Architecture
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel 1) (ASIC1) (Brain sodium channel 2) (BNaC2).

JAG1_HUMAN
θ value	6.88961 (rank : 173)	NC score	0.054125 (rank : 190)
Query Neighborhood Hits	192	Target Neighborhood Hits	514	Shared Neighborhood Hits	86
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

MMP12_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.010932 (rank : 226)
Query Neighborhood Hits	192	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

NOV_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.102462 (rank : 132)
Query Neighborhood Hits	192	Target Neighborhood Hits	128	Shared Neighborhood Hits	58
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

RSPO4_MOUSE
θ value	6.88961 (rank : 176)	NC score	0.103351 (rank : 130)
Query Neighborhood Hits	192	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

UPAR_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.006068 (rank : 233)
Query Neighborhood Hits	192	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P35456	Gene names	Plaur
Domain Architecture
Description	Urokinase plasminogen activator surface receptor, GPI-anchored form precursor (uPAR) (U-PAR) (CD87 antigen).

VWF_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.047127 (rank : 207)
Query Neighborhood Hits	192	Target Neighborhood Hits	396	Shared Neighborhood Hits	71
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WISP1_HUMAN
θ value	6.88961 (rank : 179)	NC score	0.127597 (rank : 123)
Query Neighborhood Hits	192	Target Neighborhood Hits	121	Shared Neighborhood Hits	68
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ACCN2_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.002503 (rank : 238)
Query Neighborhood Hits	192	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NXK8, Q50K97	Gene names	Accn2, Asic, Asic1, Bnac2
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel) (Acid-sensing ion channel 1) (Brain sodium channel 2).

CFAI_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.008917 (rank : 230)
Query Neighborhood Hits	192	Target Neighborhood Hits	289	Shared Neighborhood Hits	25
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CPT1B_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.001058 (rank : 240)
Query Neighborhood Hits	192	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q92523, Q13389, Q99655, Q9BY90	Gene names	CPT1B, KIAA1670
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, muscle isoform (EC 2.3.1.21) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I-like protein).

FBLN2_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.026413 (rank : 217)
Query Neighborhood Hits	192	Target Neighborhood Hits	392	Shared Neighborhood Hits	45
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FGD6_MOUSE
θ value	8.99809 (rank : 184)	NC score	-0.001657 (rank : 242)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ITK_HUMAN
θ value	8.99809 (rank : 185)	NC score	-0.009161 (rank : 244)
Query Neighborhood Hits	192	Target Neighborhood Hits	1016	Shared Neighborhood Hits	5
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

JAG2_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.054247 (rank : 189)
Query Neighborhood Hits	192	Target Neighborhood Hits	504	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KRA98_HUMAN
θ value	8.99809 (rank : 187)	NC score	0.084447 (rank : 142)
Query Neighborhood Hits	192	Target Neighborhood Hits	185	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

MMP10_MOUSE
θ value	8.99809 (rank : 188)	NC score	0.009235 (rank : 229)
Query Neighborhood Hits	192	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

MMP15_HUMAN
θ value	8.99809 (rank : 189)	NC score	0.006682 (rank : 232)
Query Neighborhood Hits	192	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

NOTC4_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.044144 (rank : 210)
Query Neighborhood Hits	192	Target Neighborhood Hits	872	Shared Neighborhood Hits	91
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SEZ6L_HUMAN
θ value	8.99809 (rank : 191)	NC score	0.002425 (rank : 239)
Query Neighborhood Hits	192	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

ZAN_HUMAN
θ value	8.99809 (rank : 192)	NC score	0.032464 (rank : 214)
Query Neighborhood Hits	192	Target Neighborhood Hits	679	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CO9_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.064837 (rank : 162)
Query Neighborhood Hits	192	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.072304 (rank : 154)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	35
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.056419 (rank : 179)
Query Neighborhood Hits	192	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.054778 (rank : 185)
Query Neighborhood Hits	192	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRIM1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.061942 (rank : 168)
Query Neighborhood Hits	192	Target Neighborhood Hits	362	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CTGF_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.088397 (rank : 137)
Query Neighborhood Hits	192	Target Neighborhood Hits	128	Shared Neighborhood Hits	60
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.092667 (rank : 135)
Query Neighborhood Hits	192	Target Neighborhood Hits	124	Shared Neighborhood Hits	59
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

DLL1_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.053189 (rank : 194)
Query Neighborhood Hits	192	Target Neighborhood Hits	456	Shared Neighborhood Hits	83
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

JAG2_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.054677 (rank : 186)
Query Neighborhood Hits	192	Target Neighborhood Hits	491	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KR101_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.071725 (rank : 156)
Query Neighborhood Hits	192	Target Neighborhood Hits	261	Shared Neighborhood Hits	66
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.086925 (rank : 139)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	69
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.101978 (rank : 133)
Query Neighborhood Hits	192	Target Neighborhood Hits	313	Shared Neighborhood Hits	74
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.057414 (rank : 177)
Query Neighborhood Hits	192	Target Neighborhood Hits	271	Shared Neighborhood Hits	58
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.105137 (rank : 129)
Query Neighborhood Hits	192	Target Neighborhood Hits	347	Shared Neighborhood Hits	84
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.084072 (rank : 144)
Query Neighborhood Hits	192	Target Neighborhood Hits	330	Shared Neighborhood Hits	69
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR109_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.061869 (rank : 169)
Query Neighborhood Hits	192	Target Neighborhood Hits	226	Shared Neighborhood Hits	51
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.060082 (rank : 173)
Query Neighborhood Hits	192	Target Neighborhood Hits	269	Shared Neighborhood Hits	60
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.060336 (rank : 172)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	55
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR412_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.055338 (rank : 184)
Query Neighborhood Hits	192	Target Neighborhood Hits	178	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.053177 (rank : 195)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.057641 (rank : 176)
Query Neighborhood Hits	192	Target Neighborhood Hits	217	Shared Neighborhood Hits	51
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA51_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.087175 (rank : 138)
Query Neighborhood Hits	192	Target Neighborhood Hits	288	Shared Neighborhood Hits	79
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.069897 (rank : 157)
Query Neighborhood Hits	192	Target Neighborhood Hits	236	Shared Neighborhood Hits	59
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.082326 (rank : 145)
Query Neighborhood Hits	192	Target Neighborhood Hits	331	Shared Neighborhood Hits	76
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.079183 (rank : 148)
Query Neighborhood Hits	192	Target Neighborhood Hits	270	Shared Neighborhood Hits	68
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.050774 (rank : 204)
Query Neighborhood Hits	192	Target Neighborhood Hits	257	Shared Neighborhood Hits	55
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.050319 (rank : 206)
Query Neighborhood Hits	192	Target Neighborhood Hits	207	Shared Neighborhood Hits	47
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.077481 (rank : 150)
Query Neighborhood Hits	192	Target Neighborhood Hits	269	Shared Neighborhood Hits	66
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.084222 (rank : 143)
Query Neighborhood Hits	192	Target Neighborhood Hits	324	Shared Neighborhood Hits	74
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.060852 (rank : 171)
Query Neighborhood Hits	192	Target Neighborhood Hits	310	Shared Neighborhood Hits	67
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.076210 (rank : 152)
Query Neighborhood Hits	192	Target Neighborhood Hits	198	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.079028 (rank : 149)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.051362 (rank : 203)
Query Neighborhood Hits	192	Target Neighborhood Hits	204	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

MT1B_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.053589 (rank : 192)
Query Neighborhood Hits	192	Target Neighborhood Hits	87	Shared Neighborhood Hits	24
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

NAGPA_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.057108 (rank : 178)
Query Neighborhood Hits	192	Target Neighborhood Hits	308	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL2_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.054544 (rank : 187)
Query Neighborhood Hits	192	Target Neighborhood Hits	449	Shared Neighborhood Hits	77
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.052913 (rank : 196)
Query Neighborhood Hits	192	Target Neighborhood Hits	436	Shared Neighborhood Hits	76
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NOTC1_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.056239 (rank : 180)
Query Neighborhood Hits	192	Target Neighborhood Hits	906	Shared Neighborhood Hits	102
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.052159 (rank : 200)
Query Neighborhood Hits	192	Target Neighborhood Hits	916	Shared Neighborhood Hits	93
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.051794 (rank : 202)
Query Neighborhood Hits	192	Target Neighborhood Hits	1113	Shared Neighborhood Hits	98
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.052047 (rank : 201)
Query Neighborhood Hits	192	Target Neighborhood Hits	1069	Shared Neighborhood Hits	92
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.052334 (rank : 198)
Query Neighborhood Hits	192	Target Neighborhood Hits	1062	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.054335 (rank : 188)
Query Neighborhood Hits	192	Target Neighborhood Hits	975	Shared Neighborhood Hits	100
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RELN_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.055375 (rank : 183)
Query Neighborhood Hits	192	Target Neighborhood Hits	233	Shared Neighborhood Hits	52
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.058026 (rank : 175)
Query Neighborhood Hits	192	Target Neighborhood Hits	235	Shared Neighborhood Hits	54
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

SPON2_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.086600 (rank : 140)
Query Neighborhood Hits	192	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON2_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.074206 (rank : 153)
Query Neighborhood Hits	192	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

SREC_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.056158 (rank : 181)
Query Neighborhood Hits	192	Target Neighborhood Hits	645	Shared Neighborhood Hits	93
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

TSP3_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.053736 (rank : 191)
Query Neighborhood Hits	192	Target Neighborhood Hits	250	Shared Neighborhood Hits	29
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.052183 (rank : 199)
Query Neighborhood Hits	192	Target Neighborhood Hits	247	Shared Neighborhood Hits	28
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.050561 (rank : 205)
Query Neighborhood Hits	192	Target Neighborhood Hits	277	Shared Neighborhood Hits	29
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.077234 (rank : 151)
Query Neighborhood Hits	192	Target Neighborhood Hits	808	Shared Neighborhood Hits	107
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

ATS20_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	192	Target Neighborhood Hits	192	Shared Neighborhood Hits	192
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
NC score	0.994178 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	192	Target Neighborhood Hits	225	Shared Neighborhood Hits	150
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS9_HUMAN
NC score	0.989810 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	151
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS15_HUMAN
NC score	0.979700 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	192	Target Neighborhood Hits	151	Shared Neighborhood Hits	133
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS1_MOUSE
NC score	0.977422 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	192	Target Neighborhood Hits	158	Shared Neighborhood Hits	134
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS1_HUMAN
NC score	0.976238 (rank : 6)	θ value	7.22167e-183 (rank : 6)
Query Neighborhood Hits	192	Target Neighborhood Hits	159	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS5_MOUSE
NC score	0.973916 (rank : 7)	θ value	1.62005e-158 (rank : 10)
Query Neighborhood Hits	192	Target Neighborhood Hits	147	Shared Neighborhood Hits	124
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS8_HUMAN
NC score	0.973205 (rank : 8)	θ value	6.12769e-174 (rank : 8)
Query Neighborhood Hits	192	Target Neighborhood Hits	145	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS18_HUMAN
NC score	0.971798 (rank : 9)	θ value	1.05009e-157 (rank : 12)
Query Neighborhood Hits	192	Target Neighborhood Hits	169	Shared Neighborhood Hits	131
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS7_HUMAN
NC score	0.971207 (rank : 10)	θ value	5.08302e-128 (rank : 20)
Query Neighborhood Hits	192	Target Neighborhood Hits	169	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS18_MOUSE
NC score	0.971178 (rank : 11)	θ value	6.80647e-157 (rank : 13)
Query Neighborhood Hits	192	Target Neighborhood Hits	163	Shared Neighborhood Hits	131
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS5_HUMAN
NC score	0.971132 (rank : 12)	θ value	4.26331e-159 (rank : 9)
Query Neighborhood Hits	192	Target Neighborhood Hits	141	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS16_MOUSE
NC score	0.969840 (rank : 13)	θ value	1.37464e-149 (rank : 17)
Query Neighborhood Hits	192	Target Neighborhood Hits	179	Shared Neighborhood Hits	139
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS12_MOUSE
NC score	0.969736 (rank : 14)	θ value	1.37464e-149 (rank : 16)
Query Neighborhood Hits	192	Target Neighborhood Hits	220	Shared Neighborhood Hits	135
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS6_HUMAN
NC score	0.969471 (rank : 15)	θ value	3.08376e-125 (rank : 24)
Query Neighborhood Hits	192	Target Neighborhood Hits	141	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS12_HUMAN
NC score	0.968633 (rank : 16)	θ value	7.28896e-151 (rank : 15)
Query Neighborhood Hits	192	Target Neighborhood Hits	251	Shared Neighborhood Hits	135
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS16_HUMAN
NC score	0.968254 (rank : 17)	θ value	4.73554e-142 (rank : 18)
Query Neighborhood Hits	192	Target Neighborhood Hits	208	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS8_MOUSE
NC score	0.967752 (rank : 18)	θ value	5.01279e-176 (rank : 7)
Query Neighborhood Hits	192	Target Neighborhood Hits	139	Shared Neighborhood Hits	122
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS17_HUMAN
NC score	0.966746 (rank : 19)	θ value	2.78914e-126 (rank : 23)
Query Neighborhood Hits	192	Target Neighborhood Hits	194	Shared Neighborhood Hits	144
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS3_HUMAN
NC score	0.964614 (rank : 20)	θ value	1.29561e-123 (rank : 26)
Query Neighborhood Hits	192	Target Neighborhood Hits	179	Shared Neighborhood Hits	138
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS2_HUMAN
NC score	0.960374 (rank : 21)	θ value	1.63515e-126 (rank : 22)
Query Neighborhood Hits	192	Target Neighborhood Hits	179	Shared Neighborhood Hits	132
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS19_MOUSE
NC score	0.959326 (rank : 22)	θ value	1.74701e-128 (rank : 19)
Query Neighborhood Hits	192	Target Neighborhood Hits	188	Shared Neighborhood Hits	131
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS4_MOUSE
NC score	0.959289 (rank : 23)	θ value	8.04023e-158 (rank : 11)
Query Neighborhood Hits	192	Target Neighborhood Hits	145	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS2_MOUSE
NC score	0.959082 (rank : 24)	θ value	8.97236e-125 (rank : 25)
Query Neighborhood Hits	192	Target Neighborhood Hits	179	Shared Neighborhood Hits	126
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS19_HUMAN
NC score	0.958453 (rank : 25)	θ value	1.25199e-126 (rank : 21)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	129
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS4_HUMAN
NC score	0.957573 (rank : 26)	θ value	1.98038e-156 (rank : 14)
Query Neighborhood Hits	192	Target Neighborhood Hits	138	Shared Neighborhood Hits	113
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS14_HUMAN
NC score	0.954221 (rank : 27)	θ value	1.53401e-116 (rank : 27)
Query Neighborhood Hits	192	Target Neighborhood Hits	382	Shared Neighborhood Hits	128
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS13_HUMAN
NC score	0.924662 (rank : 28)	θ value	4.32305e-111 (rank : 28)
Query Neighborhood Hits	192	Target Neighborhood Hits	238	Shared Neighborhood Hits	126
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
NC score	0.915596 (rank : 29)	θ value	4.41421e-39 (rank : 33)
Query Neighborhood Hits	192	Target Neighborhood Hits	227	Shared Neighborhood Hits	128
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL5_HUMAN
NC score	0.881276 (rank : 30)	θ value	1.42001e-37 (rank : 34)
Query Neighborhood Hits	192	Target Neighborhood Hits	103	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL1_HUMAN
NC score	0.879903 (rank : 31)	θ value	1.51013e-55 (rank : 30)
Query Neighborhood Hits	192	Target Neighborhood Hits	93	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
NC score	0.871683 (rank : 32)	θ value	3.16345e-37 (rank : 35)
Query Neighborhood Hits	192	Target Neighborhood Hits	80	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL2_MOUSE
NC score	0.850417 (rank : 33)	θ value	5.95217e-44 (rank : 31)
Query Neighborhood Hits	192	Target Neighborhood Hits	137	Shared Neighborhood Hits	92
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL2_HUMAN
NC score	0.849382 (rank : 34)	θ value	2.26182e-43 (rank : 32)
Query Neighborhood Hits	192	Target Neighborhood Hits	125	Shared Neighborhood Hits	91
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL3_HUMAN
NC score	0.748513 (rank : 35)	θ value	7.44272e-79 (rank : 29)
Query Neighborhood Hits	192	Target Neighborhood Hits	414	Shared Neighborhood Hits	99
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

PROP_HUMAN
NC score	0.643752 (rank : 36)	θ value	1.29331e-14 (rank : 70)
Query Neighborhood Hits	192	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
NC score	0.638147 (rank : 37)	θ value	4.44505e-15 (rank : 67)
Query Neighborhood Hits	192	Target Neighborhood Hits	165	Shared Neighborhood Hits	92
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

ADAM8_HUMAN
NC score	0.613635 (rank : 38)	θ value	2.05525e-28 (rank : 37)
Query Neighborhood Hits	192	Target Neighborhood Hits	327	Shared Neighborhood Hits	100
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA28_MOUSE
NC score	0.611157 (rank : 39)	θ value	1.08979e-29 (rank : 36)
Query Neighborhood Hits	192	Target Neighborhood Hits	241	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADAM8_MOUSE
NC score	0.609182 (rank : 40)	θ value	1.29031e-22 (rank : 42)
Query Neighborhood Hits	192	Target Neighborhood Hits	326	Shared Neighborhood Hits	104
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADA19_MOUSE
NC score	0.607646 (rank : 41)	θ value	3.75424e-22 (rank : 45)
Query Neighborhood Hits	192	Target Neighborhood Hits	315	Shared Neighborhood Hits	104
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA28_HUMAN
NC score	0.601888 (rank : 42)	θ value	1.62847e-25 (rank : 39)
Query Neighborhood Hits	192	Target Neighborhood Hits	244	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA19_HUMAN
NC score	0.599249 (rank : 43)	θ value	2.20094e-22 (rank : 44)
Query Neighborhood Hits	192	Target Neighborhood Hits	381	Shared Neighborhood Hits	101
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADEC1_HUMAN
NC score	0.593937 (rank : 44)	θ value	1.42992e-13 (rank : 79)
Query Neighborhood Hits	192	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA33_HUMAN
NC score	0.593343 (rank : 45)	θ value	1.86321e-21 (rank : 47)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

SPON1_HUMAN
NC score	0.593102 (rank : 46)	θ value	4.44505e-15 (rank : 68)
Query Neighborhood Hits	192	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

ADA12_HUMAN
NC score	0.592412 (rank : 47)	θ value	1.33526e-19 (rank : 51)
Query Neighborhood Hits	192	Target Neighborhood Hits	224	Shared Neighborhood Hits	95
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

SPON1_MOUSE
NC score	0.591788 (rank : 48)	θ value	4.44505e-15 (rank : 69)
Query Neighborhood Hits	192	Target Neighborhood Hits	123	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

ADA12_MOUSE
NC score	0.582191 (rank : 49)	θ value	1.80466e-16 (rank : 59)
Query Neighborhood Hits	192	Target Neighborhood Hits	474	Shared Neighborhood Hits	100
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM7_HUMAN
NC score	0.576591 (rank : 50)	θ value	9.87957e-23 (rank : 41)
Query Neighborhood Hits	192	Target Neighborhood Hits	221	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
NC score	0.573596 (rank : 51)	θ value	1.86321e-21 (rank : 48)
Query Neighborhood Hits	192	Target Neighborhood Hits	200	Shared Neighborhood Hits	90
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM9_MOUSE
NC score	0.569554 (rank : 52)	θ value	5.60996e-18 (rank : 54)
Query Neighborhood Hits	192	Target Neighborhood Hits	325	Shared Neighborhood Hits	104
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA33_MOUSE
NC score	0.567556 (rank : 53)	θ value	1.2077e-20 (rank : 50)
Query Neighborhood Hits	192	Target Neighborhood Hits	231	Shared Neighborhood Hits	94
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA15_HUMAN
NC score	0.566798 (rank : 54)	θ value	2.88119e-14 (rank : 73)
Query Neighborhood Hits	192	Target Neighborhood Hits	288	Shared Neighborhood Hits	100
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

CI094_HUMAN
NC score	0.563477 (rank : 55)	θ value	4.28545e-26 (rank : 38)
Query Neighborhood Hits	192	Target Neighborhood Hits	310	Shared Neighborhood Hits	74
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ADAM9_HUMAN
NC score	0.560037 (rank : 56)	θ value	5.07402e-19 (rank : 52)
Query Neighborhood Hits	192	Target Neighborhood Hits	243	Shared Neighborhood Hits	100
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADEC1_MOUSE
NC score	0.543886 (rank : 57)	θ value	6.87365e-08 (rank : 97)
Query Neighborhood Hits	192	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA22_HUMAN
NC score	0.538210 (rank : 58)	θ value	1.058e-16 (rank : 57)
Query Neighborhood Hits	192	Target Neighborhood Hits	211	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA15_MOUSE
NC score	0.536766 (rank : 59)	θ value	2.28291e-11 (rank : 83)
Query Neighborhood Hits	192	Target Neighborhood Hits	324	Shared Neighborhood Hits	103
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADM1B_MOUSE
NC score	0.534507 (rank : 60)	θ value	2.69671e-12 (rank : 82)
Query Neighborhood Hits	192	Target Neighborhood Hits	236	Shared Neighborhood Hits	98
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA23_MOUSE
NC score	0.531406 (rank : 61)	θ value	3.39556e-23 (rank : 40)
Query Neighborhood Hits	192	Target Neighborhood Hits	245	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA21_MOUSE
NC score	0.529286 (rank : 62)	θ value	8.95645e-16 (rank : 61)
Query Neighborhood Hits	192	Target Neighborhood Hits	172	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADM1A_MOUSE
NC score	0.527679 (rank : 63)	θ value	4.91457e-14 (rank : 77)
Query Neighborhood Hits	192	Target Neighborhood Hits	230	Shared Neighborhood Hits	96
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA22_MOUSE
NC score	0.527395 (rank : 64)	θ value	3.28887e-18 (rank : 53)
Query Neighborhood Hits	192	Target Neighborhood Hits	225	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
NC score	0.524526 (rank : 65)	θ value	1.6852e-22 (rank : 43)
Query Neighborhood Hits	192	Target Neighborhood Hits	235	Shared Neighborhood Hits	99
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
NC score	0.521705 (rank : 66)	θ value	1.63604e-09 (rank : 88)
Query Neighborhood Hits	192	Target Neighborhood Hits	230	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA21_HUMAN
NC score	0.514153 (rank : 67)	θ value	4.74913e-17 (rank : 56)
Query Neighborhood Hits	192	Target Neighborhood Hits	181	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA25_MOUSE
NC score	0.513777 (rank : 68)	θ value	4.16044e-13 (rank : 80)
Query Neighborhood Hits	192	Target Neighborhood Hits	213	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA29_HUMAN
NC score	0.513722 (rank : 69)	θ value	2.13673e-09 (rank : 89)
Query Neighborhood Hits	192	Target Neighborhood Hits	247	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

AD26A_MOUSE
NC score	0.510210 (rank : 70)	θ value	2.69671e-12 (rank : 81)
Query Neighborhood Hits	192	Target Neighborhood Hits	165	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA11_MOUSE
NC score	0.510092 (rank : 71)	θ value	6.64225e-11 (rank : 84)
Query Neighborhood Hits	192	Target Neighborhood Hits	263	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

THSD1_HUMAN
NC score	0.501315 (rank : 72)	θ value	0.00020696 (rank : 113)
Query Neighborhood Hits	192	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA11_HUMAN
NC score	0.487284 (rank : 73)	θ value	5.62301e-10 (rank : 86)
Query Neighborhood Hits	192	Target Neighborhood Hits	259	Shared Neighborhood Hits	96
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADAM2_MOUSE
NC score	0.475038 (rank : 74)	θ value	3.41135e-07 (rank : 100)
Query Neighborhood Hits	192	Target Neighborhood Hits	209	Shared Neighborhood Hits	94
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

TSP1_HUMAN
NC score	0.472167 (rank : 75)	θ value	2.88119e-14 (rank : 75)
Query Neighborhood Hits	192	Target Neighborhood Hits	389	Shared Neighborhood Hits	119
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.471766 (rank : 76)	θ value	2.88119e-14 (rank : 76)
Query Neighborhood Hits	192	Target Neighborhood Hits	396	Shared Neighborhood Hits	121
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

THSD1_MOUSE
NC score	0.471371 (rank : 77)	θ value	0.00035302 (rank : 115)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA20_HUMAN
NC score	0.470877 (rank : 78)	θ value	2.21117e-06 (rank : 104)
Query Neighborhood Hits	192	Target Neighborhood Hits	143	Shared Neighborhood Hits	85
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

BAI1_MOUSE
NC score	0.470396 (rank : 79)	θ value	1.52774e-15 (rank : 62)
Query Neighborhood Hits	192	Target Neighborhood Hits	340	Shared Neighborhood Hits	94
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ADA32_HUMAN
NC score	0.469347 (rank : 80)	θ value	7.34386e-10 (rank : 87)
Query Neighborhood Hits	192	Target Neighborhood Hits	216	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

BAI1_HUMAN
NC score	0.468915 (rank : 81)	θ value	1.38178e-16 (rank : 58)
Query Neighborhood Hits	192	Target Neighborhood Hits	375	Shared Neighborhood Hits	99
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
NC score	0.468123 (rank : 82)	θ value	1.68911e-14 (rank : 71)
Query Neighborhood Hits	192	Target Neighborhood Hits	332	Shared Neighborhood Hits	96
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TSP2_MOUSE
NC score	0.467570 (rank : 83)	θ value	4.91457e-14 (rank : 78)
Query Neighborhood Hits	192	Target Neighborhood Hits	352	Shared Neighborhood Hits	115
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

UNC5A_MOUSE
NC score	0.466974 (rank : 84)	θ value	1.06045e-08 (rank : 91)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

BAI2_MOUSE
NC score	0.465918 (rank : 85)	θ value	2.88119e-14 (rank : 74)
Query Neighborhood Hits	192	Target Neighborhood Hits	323	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_MOUSE
NC score	0.465606 (rank : 86)	θ value	1.99529e-15 (rank : 63)
Query Neighborhood Hits	192	Target Neighborhood Hits	250	Shared Neighborhood Hits	97
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_HUMAN
NC score	0.465455 (rank : 87)	θ value	3.40345e-15 (rank : 65)
Query Neighborhood Hits	192	Target Neighborhood Hits	246	Shared Neighborhood Hits	92
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

ADA32_MOUSE
NC score	0.465241 (rank : 88)	θ value	3.29651e-10 (rank : 85)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

TSP2_HUMAN
NC score	0.464957 (rank : 89)	θ value	3.40345e-15 (rank : 66)
Query Neighborhood Hits	192	Target Neighborhood Hits	359	Shared Neighborhood Hits	116
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

UNC5B_MOUSE
NC score	0.455927 (rank : 90)	θ value	1.06045e-08 (rank : 93)
Query Neighborhood Hits	192	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
NC score	0.453600 (rank : 91)	θ value	1.06045e-08 (rank : 92)
Query Neighborhood Hits	192	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

ADA18_MOUSE
NC score	0.448412 (rank : 92)	θ value	0.000461057 (rank : 116)
Query Neighborhood Hits	192	Target Neighborhood Hits	227	Shared Neighborhood Hits	94
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

SSPO_MOUSE
NC score	0.442263 (rank : 93)	θ value	3.17815e-21 (rank : 49)
Query Neighborhood Hits	192	Target Neighborhood Hits	800	Shared Neighborhood Hits	161
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

UNC5C_MOUSE
NC score	0.440162 (rank : 94)	θ value	3.08544e-08 (rank : 95)
Query Neighborhood Hits	192	Target Neighborhood Hits	225	Shared Neighborhood Hits	76
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.439631 (rank : 95)	θ value	3.08544e-08 (rank : 94)
Query Neighborhood Hits	192	Target Neighborhood Hits	226	Shared Neighborhood Hits	76
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

ADAM2_HUMAN
NC score	0.438894 (rank : 96)	θ value	5.26297e-08 (rank : 96)
Query Neighborhood Hits	192	Target Neighborhood Hits	175	Shared Neighborhood Hits	81
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

SEM5A_HUMAN
NC score	0.436124 (rank : 97)	θ value	1.99529e-15 (rank : 64)
Query Neighborhood Hits	192	Target Neighborhood Hits	177	Shared Neighborhood Hits	93
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

UNC5D_HUMAN
NC score	0.431152 (rank : 98)	θ value	1.99992e-07 (rank : 99)
Query Neighborhood Hits	192	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

CO8A_HUMAN
NC score	0.429645 (rank : 99)	θ value	2.13673e-09 (rank : 90)
Query Neighborhood Hits	192	Target Neighborhood Hits	200	Shared Neighborhood Hits	83
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

UNC5D_MOUSE
NC score	0.427643 (rank : 100)	θ value	3.41135e-07 (rank : 101)
Query Neighborhood Hits	192	Target Neighborhood Hits	268	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

SEM5A_MOUSE
NC score	0.426707 (rank : 101)	θ value	1.68911e-14 (rank : 72)
Query Neighborhood Hits	192	Target Neighborhood Hits	162	Shared Neighborhood Hits	90
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_MOUSE
NC score	0.425861 (rank : 102)	θ value	2.35696e-16 (rank : 60)
Query Neighborhood Hits	192	Target Neighborhood Hits	190	Shared Neighborhood Hits	94
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

ADA18_HUMAN
NC score	0.425805 (rank : 103)	θ value	7.59969e-07 (rank : 103)
Query Neighborhood Hits	192	Target Neighborhood Hits	184	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

SEM5B_HUMAN
NC score	0.424690 (rank : 104)	θ value	1.63225e-17 (rank : 55)
Query Neighborhood Hits	192	Target Neighborhood Hits	178	Shared Neighborhood Hits	92
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

CO8A_MOUSE
NC score	0.420524 (rank : 105)	θ value	1.99992e-07 (rank : 98)
Query Neighborhood Hits	192	Target Neighborhood Hits	182	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO6_HUMAN
NC score	0.417684 (rank : 106)	θ value	1.09739e-05 (rank : 107)
Query Neighborhood Hits	192	Target Neighborhood Hits	331	Shared Neighborhood Hits	102
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ADA30_HUMAN
NC score	0.416931 (rank : 107)	θ value	2.88788e-06 (rank : 105)
Query Neighborhood Hits	192	Target Neighborhood Hits	391	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA17_MOUSE
NC score	0.407667 (rank : 108)	θ value	2.44474e-05 (rank : 108)
Query Neighborhood Hits	192	Target Neighborhood Hits	201	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

CO8B_MOUSE
NC score	0.402281 (rank : 109)	θ value	7.1131e-05 (rank : 110)
Query Neighborhood Hits	192	Target Neighborhood Hits	224	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADA10_MOUSE
NC score	0.402000 (rank : 110)	θ value	0.62314 (rank : 132)
Query Neighborhood Hits	192	Target Neighborhood Hits	194	Shared Neighborhood Hits	88
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA10_HUMAN
NC score	0.399882 (rank : 111)	θ value	0.813845 (rank : 135)
Query Neighborhood Hits	192	Target Neighborhood Hits	189	Shared Neighborhood Hits	89
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

CILP2_HUMAN
NC score	0.398713 (rank : 112)	θ value	3.77169e-06 (rank : 106)
Query Neighborhood Hits	192	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

ADA17_HUMAN
NC score	0.395962 (rank : 113)	θ value	0.00175202 (rank : 117)
Query Neighborhood Hits	192	Target Neighborhood Hits	223	Shared Neighborhood Hits	92
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

UNC5A_HUMAN
NC score	0.381578 (rank : 114)	θ value	4.45536e-07 (rank : 102)
Query Neighborhood Hits	192	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

CO7_HUMAN
NC score	0.369965 (rank : 115)	θ value	0.000270298 (rank : 114)
Query Neighborhood Hits	192	Target Neighborhood Hits	278	Shared Neighborhood Hits	90
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8B_HUMAN
NC score	0.365881 (rank : 116)	θ value	2.44474e-05 (rank : 109)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	79
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CILP1_HUMAN
NC score	0.294815 (rank : 117)	θ value	0.000121331 (rank : 112)
Query Neighborhood Hits	192	Target Neighborhood Hits	266	Shared Neighborhood Hits	81
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

HMCN1_HUMAN
NC score	0.294605 (rank : 118)	θ value	6.40375e-22 (rank : 46)
Query Neighborhood Hits	192	Target Neighborhood Hits	983	Shared Neighborhood Hits	137
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CILP1_MOUSE
NC score	0.289055 (rank : 119)	θ value	0.00869519 (rank : 119)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

WISP2_MOUSE
NC score	0.159730 (rank : 120)	θ value	0.0252991 (rank : 121)
Query Neighborhood Hits	192	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WISP2_HUMAN
NC score	0.159440 (rank : 121)	θ value	0.0961366 (rank : 123)
Query Neighborhood Hits	192	Target Neighborhood Hits	126	Shared Neighborhood Hits	64
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP1_MOUSE
NC score	0.137350 (rank : 122)	θ value	0.279714 (rank : 128)
Query Neighborhood Hits	192	Target Neighborhood Hits	123	Shared Neighborhood Hits	65
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP1_HUMAN
NC score	0.127597 (rank : 123)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	192	Target Neighborhood Hits	121	Shared Neighborhood Hits	68
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

CYR61_HUMAN
NC score	0.122027 (rank : 124)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	192	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

FRAS1_MOUSE
NC score	0.115974 (rank : 125)	θ value	7.1131e-05 (rank : 111)
Query Neighborhood Hits	192	Target Neighborhood Hits	747	Shared Neighborhood Hits	120
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NOV_MOUSE
NC score	0.114410 (rank : 126)	θ value	0.365318 (rank : 129)
Query Neighborhood Hits	192	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

WISP3_HUMAN
NC score	0.110104 (rank : 127)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	192	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

CYR61_MOUSE
NC score	0.107413 (rank : 128)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	192	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

KR106_HUMAN
NC score	0.105137 (rank : 129)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	192	Target Neighborhood Hits	347	Shared Neighborhood Hits	84
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

RSPO4_MOUSE
NC score	0.103351 (rank : 130)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	192	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RSPO1_HUMAN
NC score	0.102889 (rank : 131)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	192	Target Neighborhood Hits	101	Shared Neighborhood Hits	53
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

NOV_HUMAN
NC score	0.102462 (rank : 132)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	192	Target Neighborhood Hits	128	Shared Neighborhood Hits	58
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

KR104_HUMAN
NC score	0.101978 (rank : 133)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	192	Target Neighborhood Hits	313	Shared Neighborhood Hits	74
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

FRAS1_HUMAN
NC score	0.101640 (rank : 134)	θ value	0.00509761 (rank : 118)
Query Neighborhood Hits	192	Target Neighborhood Hits	759	Shared Neighborhood Hits	116
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CTGF_MOUSE
NC score	0.092667 (rank : 135)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	192	Target Neighborhood Hits	124	Shared Neighborhood Hits	59
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

RSPO1_MOUSE
NC score	0.091756 (rank : 136)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	192	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

CTGF_HUMAN
NC score	0.088397 (rank : 137)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	192	Target Neighborhood Hits	128	Shared Neighborhood Hits	60
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

KRA51_HUMAN
NC score	0.087175 (rank : 138)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	192	Target Neighborhood Hits	288	Shared Neighborhood Hits	79
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KR102_HUMAN
NC score	0.086925 (rank : 139)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	192	Target Neighborhood Hits	264	Shared Neighborhood Hits	69
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

SPON2_HUMAN
NC score	0.086600 (rank : 140)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	192	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

RSPO4_HUMAN
NC score	0.084488 (rank : 141)	θ value	0.62314 (rank : 134)
Query Neighborhood Hits	192	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

KRA98_HUMAN
NC score	0.084447 (rank : 142)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	192	Target Neighborhood Hits	185	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA58_HUMAN
NC score	0.084222 (rank : 143)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	192	Target Neighborhood Hits	324	Shared Neighborhood Hits	74
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KR107_HUMAN
NC score	0.084072 (rank : 144)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	192	Target Neighborhood Hits	330	Shared Neighborhood Hits	69
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA53_HUMAN
NC score	0.082326 (rank : 145)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	192	Target Neighborhood Hits	331	Shared Neighborhood Hits	76
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

TENX_HUMAN
NC score	0.080354 (rank : 146)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	192	Target Neighborhood Hits	789	Shared Neighborhood Hits	103
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

RSPO3_HUMAN
NC score	0.079454 (rank : 147)	θ value	0.813845 (rank : 137)
Query Neighborhood Hits	192	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

KRA54_HUMAN
NC score	0.079183 (rank : 148)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	192	Target Neighborhood Hits	270	Shared Neighborhood Hits	68
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA93_HUMAN
NC score	0.079028 (rank : 149)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	192	Target Neighborhood Hits	203	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA57_HUMAN
NC score	0.077481 (rank : 150)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	192	Target Neighborhood Hits	269	Shared Neighborhood Hits	66
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

ZAN_MOUSE
NC score	0.077234 (rank : 151)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	192	Target Neighborhood Hits	808	Shared Neighborhood Hits	107
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KRA92_HUMAN
NC score	0.076210 (rank : 152)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	192	Target Neighborhood Hits	198	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

SPON2_MOUSE
NC score	0.074206 (rank : 153)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	192	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

CO9_MOUSE
NC score	0.072304 (rank : 154)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	192	Target Neighborhood Hits	153	Shared Neighborhood Hits	35
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

RSPO3_MOUSE
NC score	0.072292 (rank : 155)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	192	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

KR101_HUMAN
NC score	0.071725 (rank : 156)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	192	Target Neighborhood Hits	261	Shared Neighborhood Hits	66
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KRA52_HUMAN
NC score	0.069897 (rank : 157)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	192	Target Neighborhood Hits	236	Shared Neighborhood Hits	59
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

NFX1_HUMAN
NC score	0.068939 (rank : 158)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	192	Target Neighborhood Hits	405	Shared Neighborhood Hits	54
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

RSPO2_HUMAN
NC score	0.066788 (rank : 159)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	192	Target Neighborhood Hits	90	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

LRP1B_HUMAN
NC score	0.066686 (rank : 160)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	192	Target Neighborhood Hits	602	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP2_HUMAN
NC score	0.066616 (rank : 161)	θ value	0.0431538 (rank : 122)
Query Neighborhood Hits	192	Target Neighborhood Hits	573	Shared Neighborhood Hits	93
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

CO9_HUMAN
NC score	0.064837 (rank : 162)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	192	Target Neighborhood Hits	147	Shared Neighborhood Hits	28
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

MEGF6_HUMAN
NC score	0.064704 (rank : 163)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	192	Target Neighborhood Hits	671	Shared Neighborhood Hits	116
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TENA_MOUSE
NC score	0.064581 (rank : 164)	θ value	0.0193708 (rank : 120)
Query Neighborhood Hits	192	Target Neighborhood Hits	596	Shared Neighborhood Hits	84
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

LRP1_HUMAN
NC score	0.064515 (rank : 165)	θ value	0.279714 (rank : 127)
Query Neighborhood Hits	192	Target Neighborhood Hits	617	Shared Neighborhood Hits	99
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_MOUSE
NC score	0.062485 (rank : 166)	θ value	0.47712 (rank : 131)
Query Neighborhood Hits	192	Target Neighborhood Hits	606	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

PCSK5_MOUSE
NC score	0.062065 (rank : 167)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	192	Target Neighborhood Hits	613	Shared Neighborhood Hits	89
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CRIM1_HUMAN
NC score	0.061942 (rank : 168)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	192	Target Neighborhood Hits	362	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR109_HUMAN
NC score	0.061869 (rank : 169)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	192	Target Neighborhood Hits	226	Shared Neighborhood Hits	51
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

RSPO2_MOUSE
NC score	0.061440 (rank : 170)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	192	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

KRA59_HUMAN
NC score	0.060852 (rank : 171)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	192	Target Neighborhood Hits	310	Shared Neighborhood Hits	67
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KR10C_HUMAN
NC score	0.060336 (rank : 172)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	192	Target Neighborhood Hits	219	Shared Neighborhood Hits	55
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR10B_HUMAN
NC score	0.060082 (rank : 173)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	192	Target Neighborhood Hits	269	Shared Neighborhood Hits	60
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

TENA_HUMAN
NC score	0.058737 (rank : 174)	θ value	0.125558 (rank : 126)
Query Neighborhood Hits	192	Target Neighborhood Hits	631	Shared Neighborhood Hits	87
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

RELN_MOUSE
NC score	0.058026 (rank : 175)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	192	Target Neighborhood Hits	235	Shared Neighborhood Hits	54
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

KR510_HUMAN
NC score	0.057641 (rank : 176)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	192	Target Neighborhood Hits	217	Shared Neighborhood Hits	51
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR105_HUMAN
NC score	0.057414 (rank : 177)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	192	Target Neighborhood Hits	271	Shared Neighborhood Hits	58
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

NAGPA_MOUSE
NC score	0.057108 (rank : 178)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	192	Target Neighborhood Hits	308	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

COMP_HUMAN
NC score	0.056419 (rank : 179)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	192	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NOTC1_HUMAN
NC score	0.056239 (rank : 180)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	192	Target Neighborhood Hits	906	Shared Neighborhood Hits	102
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SREC_HUMAN
NC score	0.056158 (rank : 181)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	192	Target Neighborhood Hits	645	Shared Neighborhood Hits	93
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SREC2_MOUSE
NC score	0.055994 (rank : 182)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	192	Target Neighborhood Hits	605	Shared Neighborhood Hits	80
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

RELN_HUMAN
NC score	0.055375 (rank : 183)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	192	Target Neighborhood Hits	233	Shared Neighborhood Hits	52
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

KR412_HUMAN
NC score	0.055338 (rank : 184)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	192	Target Neighborhood Hits	178	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

COMP_MOUSE
NC score	0.054778 (rank : 185)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	192	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

JAG2_HUMAN
NC score	0.054677 (rank : 186)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	192	Target Neighborhood Hits	491	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NELL2_HUMAN
NC score	0.054544 (rank : 187)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	192	Target Neighborhood Hits	449	Shared Neighborhood Hits	77
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NOTC3_MOUSE
NC score	0.054335 (rank : 188)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	192	Target Neighborhood Hits	975	Shared Neighborhood Hits	100
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

JAG2_MOUSE
NC score	0.054247 (rank : 189)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	192	Target Neighborhood Hits	504	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

JAG1_HUMAN
NC score	0.054125 (rank : 190)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	192	Target Neighborhood Hits	514	Shared Neighborhood Hits	86
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

TSP3_HUMAN
NC score	0.053736 (rank : 191)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	192	Target Neighborhood Hits	250	Shared Neighborhood Hits	29
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

MT1B_HUMAN
NC score	0.053589 (rank : 192)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	192	Target Neighborhood Hits	87	Shared Neighborhood Hits	24
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

JAG1_MOUSE
NC score	0.053232 (rank : 193)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	192	Target Neighborhood Hits	518	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DLL1_MOUSE
NC score	0.053189 (rank : 194)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	192	Target Neighborhood Hits	456	Shared Neighborhood Hits	83
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

KR414_HUMAN
NC score	0.053177 (rank : 195)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	192	Target Neighborhood Hits	199	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

NELL2_MOUSE
NC score	0.052913 (rank : 196)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	192	Target Neighborhood Hits	436	Shared Neighborhood Hits	76
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

SREC2_HUMAN
NC score	0.052417 (rank : 197)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	192	Target Neighborhood Hits	645	Shared Neighborhood Hits	77
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

NOTC3_HUMAN
NC score	0.052334 (rank : 198)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	192	Target Neighborhood Hits	1062	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TSP3_MOUSE
NC score	0.052183 (rank : 199)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	192	Target Neighborhood Hits	247	Shared Neighborhood Hits	28
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

NOTC1_MOUSE
NC score	0.052159 (rank : 200)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	192	Target Neighborhood Hits	916	Shared Neighborhood Hits	93
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
NC score	0.052047 (rank : 201)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	192	Target Neighborhood Hits	1069	Shared Neighborhood Hits	92
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.051794 (rank : 202)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	192	Target Neighborhood Hits	1113	Shared Neighborhood Hits	98
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KRA94_HUMAN
NC score	0.051362 (rank : 203)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	192	Target Neighborhood Hits	204	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA55_HUMAN
NC score	0.050774 (rank : 204)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	192	Target Neighborhood Hits	257	Shared Neighborhood Hits	55
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

TSP4_HUMAN
NC score	0.050561 (rank : 205)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	192	Target Neighborhood Hits	277	Shared Neighborhood Hits	29
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

KRA56_HUMAN
NC score	0.050319 (rank : 206)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	192	Target Neighborhood Hits	207	Shared Neighborhood Hits	47
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

VWF_HUMAN
NC score	0.047127 (rank : 207)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	192	Target Neighborhood Hits	396	Shared Neighborhood Hits	71
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

AGRIN_HUMAN
NC score	0.046018 (rank : 208)	θ value	0.125558 (rank : 124)
Query Neighborhood Hits	192	Target Neighborhood Hits	582	Shared Neighborhood Hits	77
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

LTBP3_MOUSE
NC score	0.045217 (rank : 209)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	192	Target Neighborhood Hits	475	Shared Neighborhood Hits	78
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NOTC4_MOUSE
NC score	0.044144 (rank : 210)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	192	Target Neighborhood Hits	872	Shared Neighborhood Hits	91
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NAGPA_HUMAN
NC score	0.044097 (rank : 211)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LTBP4_MOUSE
NC score	0.041488 (rank : 212)	θ value	1.06291 (rank : 140)
Query Neighborhood Hits	192	Target Neighborhood Hits	607	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MEGF8_HUMAN
NC score	0.034863 (rank : 213)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	192	Target Neighborhood Hits	528	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

ZAN_HUMAN
NC score	0.032464 (rank : 214)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	192	Target Neighborhood Hits	679	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

GRN_MOUSE
NC score	0.029187 (rank : 215)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	192	Target Neighborhood Hits	248	Shared Neighborhood Hits	45
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

CHRD_MOUSE
NC score	0.027711 (rank : 216)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	192	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

FBLN2_HUMAN
NC score	0.026413 (rank : 217)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	192	Target Neighborhood Hits	392	Shared Neighborhood Hits	45
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LAMA5_HUMAN
NC score	0.022970 (rank : 218)	θ value	0.62314 (rank : 133)
Query Neighborhood Hits	192	Target Neighborhood Hits	976	Shared Neighborhood Hits	70
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

RXINP_MOUSE
NC score	0.020595 (rank : 219)	θ value	0.125558 (rank : 125)
Query Neighborhood Hits	192	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

SLIT3_HUMAN
NC score	0.018558 (rank : 220)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	192	Target Neighborhood Hits	682	Shared Neighborhood Hits	59
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

LYAM3_HUMAN
NC score	0.015479 (rank : 221)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	192	Target Neighborhood Hits	378	Shared Neighborhood Hits	39
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MMP13_MOUSE
NC score	0.014635 (rank : 222)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	192	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	P33435	Gene names	Mmp13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

HPS4_MOUSE
NC score	0.013567 (rank : 223)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	192	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

MMP28_HUMAN
NC score	0.012073 (rank : 224)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	192	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

MMP12_MOUSE
NC score	0.010997 (rank : 225)	θ value	0.813845 (rank : 136)
Query Neighborhood Hits	192	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	P34960, Q8BJ92, Q8BJB3, Q8BJB6, Q8BJB8, Q8BJB9, Q8VED6	Gene names	Mmp12, Mme, Mmel
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (MME) (Matrix metalloproteinase-12) (MMP-12).

MMP12_HUMAN
NC score	0.010932 (rank : 226)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	192	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

MMP15_MOUSE
NC score	0.010131 (rank : 227)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	192	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

GLCM_HUMAN
NC score	0.009900 (rank : 228)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	192	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P04062, Q16545, Q9UMJ8	Gene names	GBA, GC
Domain Architecture
Description	Glucosylceramidase precursor (EC 3.2.1.45) (Beta-glucocerebrosidase) (Acid beta-glucosidase) (D-glucosyl-N-acylsphingosine glucohydrolase) (Alglucerase) (Imiglucerase).

MMP10_MOUSE
NC score	0.009235 (rank : 229)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	192	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

CFAI_HUMAN
NC score	0.008917 (rank : 230)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	192	Target Neighborhood Hits	289	Shared Neighborhood Hits	25
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

MPRI_MOUSE
NC score	0.008420 (rank : 231)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	192	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

MMP15_HUMAN
NC score	0.006682 (rank : 232)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	192	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

UPAR_MOUSE
NC score	0.006068 (rank : 233)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	192	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P35456	Gene names	Plaur
Domain Architecture
Description	Urokinase plasminogen activator surface receptor, GPI-anchored form precursor (uPAR) (U-PAR) (CD87 antigen).

SPRE1_MOUSE
NC score	0.005718 (rank : 234)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	192	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

CRIS2_HUMAN
NC score	0.005700 (rank : 235)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	192	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P16562	Gene names	CRISP2, TPX1
Domain Architecture
Description	Cysteine-rich secretory protein 2 precursor (CRISP-2) (Testis-specific protein TPX-1).

APOA_HUMAN
NC score	0.004233 (rank : 236)	θ value	0.47712 (rank : 130)
Query Neighborhood Hits	192	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

ACCN2_HUMAN
NC score	0.002855 (rank : 237)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	192	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P78348, P78349, Q96CV2	Gene names	ACCN2, ASIC1, BNAC2
Domain Architecture
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel 1) (ASIC1) (Brain sodium channel 2) (BNaC2).

ACCN2_MOUSE
NC score	0.002503 (rank : 238)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	192	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NXK8, Q50K97	Gene names	Accn2, Asic, Asic1, Bnac2
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 2, neuronal (Acid-sensing ion channel) (Acid-sensing ion channel 1) (Brain sodium channel 2).

SEZ6L_HUMAN
NC score	0.002425 (rank : 239)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	192	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CPT1B_HUMAN
NC score	0.001058 (rank : 240)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	192	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q92523, Q13389, Q99655, Q9BY90	Gene names	CPT1B, KIAA1670
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, muscle isoform (EC 2.3.1.21) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I-like protein).

ABCA9_MOUSE
NC score	0.000148 (rank : 241)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	192	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

FGD6_MOUSE
NC score	-0.001657 (rank : 242)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	192	Target Neighborhood Hits	282	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ZN214_HUMAN
NC score	-0.008367 (rank : 243)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	192	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UL59	Gene names	ZNF214, BAZ1
Domain Architecture
Description	Zinc finger protein 214 (BWSCR2-associated zinc-finger protein 1) (BAZ 1).

ITK_HUMAN
NC score	-0.009161 (rank : 244)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	192	Target Neighborhood Hits	1016	Shared Neighborhood Hits	5
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).