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Network neighborhood for query Sequence : ATS20_MOUSE

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ATS20_MOUSE
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATS15_HUMAN
θ value	0 (rank : 1)	NC score	0.980648 (rank : 4)
Query Neighborhood Hits	225	Target Neighborhood Hits	151	Shared Neighborhood Hits	134
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS1_HUMAN
θ value	0 (rank : 2)	NC score	0.977891 (rank : 6)
Query Neighborhood Hits	225	Target Neighborhood Hits	159	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
θ value	0 (rank : 3)	NC score	0.978555 (rank : 5)
Query Neighborhood Hits	225	Target Neighborhood Hits	158	Shared Neighborhood Hits	138
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS20_HUMAN
θ value	0 (rank : 4)	NC score	0.994178 (rank : 2)
Query Neighborhood Hits	225	Target Neighborhood Hits	192	Shared Neighborhood Hits	150
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	225
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS9_HUMAN
θ value	0 (rank : 6)	NC score	0.992210 (rank : 3)
Query Neighborhood Hits	225	Target Neighborhood Hits	219	Shared Neighborhood Hits	157
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS8_HUMAN
θ value	7.7336e-177 (rank : 7)	NC score	0.973740 (rank : 7)
Query Neighborhood Hits	225	Target Neighborhood Hits	145	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS8_MOUSE
θ value	1.23469e-174 (rank : 8)	NC score	0.968716 (rank : 16)
Query Neighborhood Hits	225	Target Neighborhood Hits	139	Shared Neighborhood Hits	122
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS18_MOUSE
θ value	5.19945e-165 (rank : 9)	NC score	0.973291 (rank : 8)
Query Neighborhood Hits	225	Target Neighborhood Hits	163	Shared Neighborhood Hits	134
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_HUMAN
θ value	5.74867e-164 (rank : 10)	NC score	0.972730 (rank : 9)
Query Neighborhood Hits	225	Target Neighborhood Hits	169	Shared Neighborhood Hits	134
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS4_MOUSE
θ value	7.508e-164 (rank : 11)	NC score	0.961145 (rank : 22)
Query Neighborhood Hits	225	Target Neighborhood Hits	145	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS5_HUMAN
θ value	5.03607e-160 (rank : 12)	NC score	0.969660 (rank : 13)
Query Neighborhood Hits	225	Target Neighborhood Hits	141	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS5_MOUSE
θ value	1.91371e-159 (rank : 13)	NC score	0.972301 (rank : 10)
Query Neighborhood Hits	225	Target Neighborhood Hits	147	Shared Neighborhood Hits	127
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS4_HUMAN
θ value	5.56804e-159 (rank : 14)	NC score	0.959836 (rank : 24)
Query Neighborhood Hits	225	Target Neighborhood Hits	138	Shared Neighborhood Hits	115
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS12_MOUSE
θ value	2.18956e-155 (rank : 15)	NC score	0.969349 (rank : 15)
Query Neighborhood Hits	225	Target Neighborhood Hits	220	Shared Neighborhood Hits	138
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS16_MOUSE
θ value	1.85358e-154 (rank : 16)	NC score	0.971113 (rank : 11)
Query Neighborhood Hits	225	Target Neighborhood Hits	179	Shared Neighborhood Hits	142
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS12_HUMAN
θ value	1.24331e-150 (rank : 17)	NC score	0.967907 (rank : 17)
Query Neighborhood Hits	225	Target Neighborhood Hits	251	Shared Neighborhood Hits	138
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS16_HUMAN
θ value	1.79534e-149 (rank : 18)	NC score	0.969902 (rank : 12)
Query Neighborhood Hits	225	Target Neighborhood Hits	208	Shared Neighborhood Hits	142
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS6_HUMAN
θ value	9.26343e-130 (rank : 19)	NC score	0.966296 (rank : 18)
Query Neighborhood Hits	225	Target Neighborhood Hits	141	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS7_HUMAN
θ value	2.06368e-129 (rank : 20)	NC score	0.969454 (rank : 14)
Query Neighborhood Hits	225	Target Neighborhood Hits	169	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS17_HUMAN
θ value	9.58617e-127 (rank : 21)	NC score	0.965980 (rank : 19)
Query Neighborhood Hits	225	Target Neighborhood Hits	194	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS2_HUMAN
θ value	2.78914e-126 (rank : 22)	NC score	0.961767 (rank : 21)
Query Neighborhood Hits	225	Target Neighborhood Hits	179	Shared Neighborhood Hits	132
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	5.26011e-125 (rank : 23)	NC score	0.963345 (rank : 20)
Query Neighborhood Hits	225	Target Neighborhood Hits	179	Shared Neighborhood Hits	142
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS2_MOUSE
θ value	1.99884e-124 (rank : 24)	NC score	0.960149 (rank : 23)
Query Neighborhood Hits	225	Target Neighborhood Hits	179	Shared Neighborhood Hits	127
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS19_HUMAN
θ value	4.45295e-124 (rank : 25)	NC score	0.957430 (rank : 26)
Query Neighborhood Hits	225	Target Neighborhood Hits	203	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_MOUSE
θ value	5.44333e-122 (rank : 26)	NC score	0.958626 (rank : 25)
Query Neighborhood Hits	225	Target Neighborhood Hits	188	Shared Neighborhood Hits	132
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS13_HUMAN
θ value	2.70778e-113 (rank : 27)	NC score	0.933544 (rank : 28)
Query Neighborhood Hits	225	Target Neighborhood Hits	238	Shared Neighborhood Hits	123
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
θ value	1.39067e-109 (rank : 28)	NC score	0.927488 (rank : 29)
Query Neighborhood Hits	225	Target Neighborhood Hits	227	Shared Neighborhood Hits	127
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS14_HUMAN
θ value	1.30163e-107 (rank : 29)	NC score	0.953390 (rank : 27)
Query Neighborhood Hits	225	Target Neighborhood Hits	382	Shared Neighborhood Hits	133
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATL3_HUMAN
θ value	1.40038e-85 (rank : 30)	NC score	0.756771 (rank : 35)
Query Neighborhood Hits	225	Target Neighborhood Hits	414	Shared Neighborhood Hits	101
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATL1_HUMAN
θ value	3.25095e-58 (rank : 31)	NC score	0.886967 (rank : 30)
Query Neighborhood Hits	225	Target Neighborhood Hits	93	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL2_MOUSE
θ value	2.04573e-44 (rank : 32)	NC score	0.858891 (rank : 33)
Query Neighborhood Hits	225	Target Neighborhood Hits	137	Shared Neighborhood Hits	94
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL2_HUMAN
θ value	1.73182e-43 (rank : 33)	NC score	0.858256 (rank : 34)
Query Neighborhood Hits	225	Target Neighborhood Hits	125	Shared Neighborhood Hits	92
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL1_MOUSE
θ value	2.58786e-39 (rank : 34)	NC score	0.877659 (rank : 32)
Query Neighborhood Hits	225	Target Neighborhood Hits	80	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL5_HUMAN
θ value	1.01765e-35 (rank : 35)	NC score	0.886541 (rank : 31)
Query Neighborhood Hits	225	Target Neighborhood Hits	103	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ADA19_MOUSE
θ value	5.06226e-27 (rank : 36)	NC score	0.590971 (rank : 43)
Query Neighborhood Hits	225	Target Neighborhood Hits	315	Shared Neighborhood Hits	114
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA28_MOUSE
θ value	5.06226e-27 (rank : 37)	NC score	0.591999 (rank : 41)
Query Neighborhood Hits	225	Target Neighborhood Hits	241	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

CI094_HUMAN
θ value	1.47289e-26 (rank : 38)	NC score	0.571617 (rank : 49)
Query Neighborhood Hits	225	Target Neighborhood Hits	310	Shared Neighborhood Hits	78
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ADA19_HUMAN
θ value	2.51237e-26 (rank : 39)	NC score	0.582377 (rank : 45)
Query Neighborhood Hits	225	Target Neighborhood Hits	381	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA28_HUMAN
θ value	4.01107e-24 (rank : 40)	NC score	0.583195 (rank : 44)
Query Neighborhood Hits	225	Target Neighborhood Hits	244	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADAM8_HUMAN
θ value	6.84181e-24 (rank : 41)	NC score	0.595555 (rank : 40)
Query Neighborhood Hits	225	Target Neighborhood Hits	327	Shared Neighborhood Hits	106
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	1.16704e-23 (rank : 42)	NC score	0.591101 (rank : 42)
Query Neighborhood Hits	225	Target Neighborhood Hits	326	Shared Neighborhood Hits	110
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

HMCN1_HUMAN
θ value	1.99067e-23 (rank : 43)	NC score	0.303647 (rank : 117)
Query Neighborhood Hits	225	Target Neighborhood Hits	983	Shared Neighborhood Hits	151
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

SSPO_MOUSE
θ value	3.75424e-22 (rank : 44)	NC score	0.450653 (rank : 89)
Query Neighborhood Hits	225	Target Neighborhood Hits	800	Shared Neighborhood Hits	173
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ADA33_HUMAN
θ value	4.15078e-21 (rank : 45)	NC score	0.575329 (rank : 47)
Query Neighborhood Hits	225	Target Neighborhood Hits	264	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA12_HUMAN
θ value	1.5773e-20 (rank : 46)	NC score	0.573377 (rank : 48)
Query Neighborhood Hits	225	Target Neighborhood Hits	224	Shared Neighborhood Hits	99
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

SPON1_HUMAN
θ value	3.51386e-20 (rank : 47)	NC score	0.607461 (rank : 38)
Query Neighborhood Hits	225	Target Neighborhood Hits	117	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

BAI2_MOUSE
θ value	1.33526e-19 (rank : 48)	NC score	0.476689 (rank : 80)
Query Neighborhood Hits	225	Target Neighborhood Hits	323	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
θ value	2.27762e-19 (rank : 49)	NC score	0.479069 (rank : 76)
Query Neighborhood Hits	225	Target Neighborhood Hits	332	Shared Neighborhood Hits	100
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

SPON1_MOUSE
θ value	2.27762e-19 (rank : 50)	NC score	0.606016 (rank : 39)
Query Neighborhood Hits	225	Target Neighborhood Hits	123	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

BAI1_HUMAN
θ value	3.88503e-19 (rank : 51)	NC score	0.478469 (rank : 77)
Query Neighborhood Hits	225	Target Neighborhood Hits	375	Shared Neighborhood Hits	97
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ADA33_MOUSE
θ value	6.62687e-19 (rank : 52)	NC score	0.548865 (rank : 54)
Query Neighborhood Hits	225	Target Neighborhood Hits	231	Shared Neighborhood Hits	97
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

SEM5B_HUMAN
θ value	1.13037e-18 (rank : 53)	NC score	0.430858 (rank : 100)
Query Neighborhood Hits	225	Target Neighborhood Hits	178	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ADAM9_HUMAN
θ value	3.28887e-18 (rank : 54)	NC score	0.540080 (rank : 56)
Query Neighborhood Hits	225	Target Neighborhood Hits	243	Shared Neighborhood Hits	100
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

BAI1_MOUSE
θ value	3.28887e-18 (rank : 55)	NC score	0.479823 (rank : 75)
Query Neighborhood Hits	225	Target Neighborhood Hits	340	Shared Neighborhood Hits	94
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ADA12_MOUSE
θ value	9.56915e-18 (rank : 56)	NC score	0.563596 (rank : 50)
Query Neighborhood Hits	225	Target Neighborhood Hits	474	Shared Neighborhood Hits	104
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM9_MOUSE
θ value	9.56915e-18 (rank : 57)	NC score	0.550351 (rank : 53)
Query Neighborhood Hits	225	Target Neighborhood Hits	325	Shared Neighborhood Hits	105
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADAM7_HUMAN
θ value	1.24977e-17 (rank : 58)	NC score	0.557517 (rank : 51)
Query Neighborhood Hits	225	Target Neighborhood Hits	221	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

SEM5A_HUMAN
θ value	1.63225e-17 (rank : 59)	NC score	0.442723 (rank : 93)
Query Neighborhood Hits	225	Target Neighborhood Hits	177	Shared Neighborhood Hits	97
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

PROP_HUMAN
θ value	2.7842e-17 (rank : 60)	NC score	0.654479 (rank : 36)
Query Neighborhood Hits	225	Target Neighborhood Hits	126	Shared Neighborhood Hits	93
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

ADAM7_MOUSE
θ value	3.63628e-17 (rank : 61)	NC score	0.554222 (rank : 52)
Query Neighborhood Hits	225	Target Neighborhood Hits	200	Shared Neighborhood Hits	96
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

SEM5A_MOUSE
θ value	4.74913e-17 (rank : 62)	NC score	0.433203 (rank : 97)
Query Neighborhood Hits	225	Target Neighborhood Hits	162	Shared Neighborhood Hits	95
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ADEC1_HUMAN
θ value	3.07829e-16 (rank : 63)	NC score	0.576598 (rank : 46)
Query Neighborhood Hits	225	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA23_HUMAN
θ value	1.52774e-15 (rank : 64)	NC score	0.502773 (rank : 66)
Query Neighborhood Hits	225	Target Neighborhood Hits	235	Shared Neighborhood Hits	100
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA11_MOUSE
θ value	3.40345e-15 (rank : 65)	NC score	0.490176 (rank : 71)
Query Neighborhood Hits	225	Target Neighborhood Hits	263	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA22_HUMAN
θ value	3.40345e-15 (rank : 66)	NC score	0.517103 (rank : 59)
Query Neighborhood Hits	225	Target Neighborhood Hits	211	Shared Neighborhood Hits	96
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

TSP1_HUMAN
θ value	4.44505e-15 (rank : 67)	NC score	0.482599 (rank : 73)
Query Neighborhood Hits	225	Target Neighborhood Hits	389	Shared Neighborhood Hits	131
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	4.44505e-15 (rank : 68)	NC score	0.481906 (rank : 74)
Query Neighborhood Hits	225	Target Neighborhood Hits	396	Shared Neighborhood Hits	133
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADA11_HUMAN
θ value	5.8054e-15 (rank : 69)	NC score	0.467373 (rank : 85)
Query Neighborhood Hits	225	Target Neighborhood Hits	259	Shared Neighborhood Hits	101
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

TSP2_HUMAN
θ value	5.8054e-15 (rank : 70)	NC score	0.475116 (rank : 82)
Query Neighborhood Hits	225	Target Neighborhood Hits	359	Shared Neighborhood Hits	125
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	5.8054e-15 (rank : 71)	NC score	0.477449 (rank : 79)
Query Neighborhood Hits	225	Target Neighborhood Hits	352	Shared Neighborhood Hits	123
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADA23_MOUSE
θ value	7.58209e-15 (rank : 72)	NC score	0.509552 (rank : 61)
Query Neighborhood Hits	225	Target Neighborhood Hits	245	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

BAI3_HUMAN
θ value	7.58209e-15 (rank : 73)	NC score	0.474683 (rank : 83)
Query Neighborhood Hits	225	Target Neighborhood Hits	246	Shared Neighborhood Hits	95
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	7.58209e-15 (rank : 74)	NC score	0.475337 (rank : 81)
Query Neighborhood Hits	225	Target Neighborhood Hits	250	Shared Neighborhood Hits	101
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

PROP_MOUSE
θ value	7.58209e-15 (rank : 75)	NC score	0.649002 (rank : 37)
Query Neighborhood Hits	225	Target Neighborhood Hits	165	Shared Neighborhood Hits	95
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SEM5B_MOUSE
θ value	1.29331e-14 (rank : 76)	NC score	0.432065 (rank : 98)
Query Neighborhood Hits	225	Target Neighborhood Hits	190	Shared Neighborhood Hits	95
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

ADA22_MOUSE
θ value	8.38298e-14 (rank : 77)	NC score	0.505958 (rank : 65)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA21_MOUSE
θ value	1.09485e-13 (rank : 78)	NC score	0.506727 (rank : 63)
Query Neighborhood Hits	225	Target Neighborhood Hits	172	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADEC1_MOUSE
θ value	1.2105e-12 (rank : 79)	NC score	0.526919 (rank : 57)
Query Neighborhood Hits	225	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADM1A_MOUSE
θ value	6.00763e-12 (rank : 80)	NC score	0.506678 (rank : 64)
Query Neighborhood Hits	225	Target Neighborhood Hits	230	Shared Neighborhood Hits	107
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

AD26A_MOUSE
θ value	3.89403e-11 (rank : 81)	NC score	0.488050 (rank : 72)
Query Neighborhood Hits	225	Target Neighborhood Hits	165	Shared Neighborhood Hits	92
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADM1B_MOUSE
θ value	5.08577e-11 (rank : 82)	NC score	0.513313 (rank : 60)
Query Neighborhood Hits	225	Target Neighborhood Hits	236	Shared Neighborhood Hits	104
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA21_HUMAN
θ value	6.64225e-11 (rank : 83)	NC score	0.490401 (rank : 70)
Query Neighborhood Hits	225	Target Neighborhood Hits	181	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA15_HUMAN
θ value	4.30538e-10 (rank : 84)	NC score	0.547669 (rank : 55)
Query Neighborhood Hits	225	Target Neighborhood Hits	288	Shared Neighborhood Hits	108
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA32_HUMAN
θ value	5.62301e-10 (rank : 85)	NC score	0.447704 (rank : 90)
Query Neighborhood Hits	225	Target Neighborhood Hits	216	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA24_MOUSE
θ value	1.25267e-09 (rank : 86)	NC score	0.499594 (rank : 67)
Query Neighborhood Hits	225	Target Neighborhood Hits	230	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADAM2_MOUSE
θ value	1.63604e-09 (rank : 87)	NC score	0.453315 (rank : 88)
Query Neighborhood Hits	225	Target Neighborhood Hits	209	Shared Neighborhood Hits	100
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

UNC5A_MOUSE
θ value	6.21693e-09 (rank : 88)	NC score	0.468870 (rank : 84)
Query Neighborhood Hits	225	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

CO8A_HUMAN
θ value	2.36244e-08 (rank : 89)	NC score	0.433390 (rank : 96)
Query Neighborhood Hits	225	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ADA29_HUMAN
θ value	8.97725e-08 (rank : 90)	NC score	0.490523 (rank : 69)
Query Neighborhood Hits	225	Target Neighborhood Hits	247	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA15_MOUSE
θ value	1.53129e-07 (rank : 91)	NC score	0.517685 (rank : 58)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	110
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

UNC5B_HUMAN
θ value	1.53129e-07 (rank : 92)	NC score	0.455191 (rank : 87)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	1.53129e-07 (rank : 93)	NC score	0.457513 (rank : 86)
Query Neighborhood Hits	225	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

ADAM2_HUMAN
θ value	3.41135e-07 (rank : 94)	NC score	0.417188 (rank : 105)
Query Neighborhood Hits	225	Target Neighborhood Hits	175	Shared Neighborhood Hits	90
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

UNC5A_HUMAN
θ value	4.45536e-07 (rank : 95)	NC score	0.380403 (rank : 113)
Query Neighborhood Hits	225	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5D_HUMAN
θ value	4.45536e-07 (rank : 96)	NC score	0.431954 (rank : 99)
Query Neighborhood Hits	225	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

CO8A_MOUSE
θ value	5.81887e-07 (rank : 97)	NC score	0.426413 (rank : 102)
Query Neighborhood Hits	225	Target Neighborhood Hits	182	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

UNC5D_MOUSE
θ value	5.81887e-07 (rank : 98)	NC score	0.428374 (rank : 101)
Query Neighborhood Hits	225	Target Neighborhood Hits	268	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5C_HUMAN
θ value	7.59969e-07 (rank : 99)	NC score	0.440406 (rank : 95)
Query Neighborhood Hits	225	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	7.59969e-07 (rank : 100)	NC score	0.440938 (rank : 94)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

CO6_HUMAN
θ value	9.92553e-07 (rank : 101)	NC score	0.424704 (rank : 104)
Query Neighborhood Hits	225	Target Neighborhood Hits	331	Shared Neighborhood Hits	103
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ADA25_MOUSE
θ value	2.21117e-06 (rank : 102)	NC score	0.490585 (rank : 68)
Query Neighborhood Hits	225	Target Neighborhood Hits	213	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA32_MOUSE
θ value	8.40245e-06 (rank : 103)	NC score	0.443600 (rank : 92)
Query Neighborhood Hits	225	Target Neighborhood Hits	219	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CILP2_HUMAN
θ value	8.40245e-06 (rank : 104)	NC score	0.403037 (rank : 108)
Query Neighborhood Hits	225	Target Neighborhood Hits	307	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CO8B_HUMAN
θ value	1.09739e-05 (rank : 105)	NC score	0.372254 (rank : 116)
Query Neighborhood Hits	225	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	1.09739e-05 (rank : 106)	NC score	0.408492 (rank : 106)
Query Neighborhood Hits	225	Target Neighborhood Hits	224	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO7_HUMAN
θ value	1.87187e-05 (rank : 107)	NC score	0.378049 (rank : 115)
Query Neighborhood Hits	225	Target Neighborhood Hits	278	Shared Neighborhood Hits	92
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

TENX_HUMAN
θ value	4.1701e-05 (rank : 108)	NC score	0.083799 (rank : 145)
Query Neighborhood Hits	225	Target Neighborhood Hits	789	Shared Neighborhood Hits	112
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ADA30_HUMAN
θ value	5.44631e-05 (rank : 109)	NC score	0.395142 (rank : 109)
Query Neighborhood Hits	225	Target Neighborhood Hits	391	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

THSD1_MOUSE
θ value	5.44631e-05 (rank : 110)	NC score	0.477746 (rank : 78)
Query Neighborhood Hits	225	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CILP1_HUMAN
θ value	9.29e-05 (rank : 111)	NC score	0.296017 (rank : 118)
Query Neighborhood Hits	225	Target Neighborhood Hits	266	Shared Neighborhood Hits	82
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

FRAS1_MOUSE
θ value	0.000158464 (rank : 112)	NC score	0.118026 (rank : 128)
Query Neighborhood Hits	225	Target Neighborhood Hits	747	Shared Neighborhood Hits	135
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ADA20_HUMAN
θ value	0.00020696 (rank : 113)	NC score	0.446608 (rank : 91)
Query Neighborhood Hits	225	Target Neighborhood Hits	143	Shared Neighborhood Hits	84
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

THSD1_HUMAN
θ value	0.00035302 (rank : 114)	NC score	0.507255 (rank : 62)
Query Neighborhood Hits	225	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA18_HUMAN
θ value	0.000602161 (rank : 115)	NC score	0.403041 (rank : 107)
Query Neighborhood Hits	225	Target Neighborhood Hits	184	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA10_MOUSE
θ value	0.00228821 (rank : 116)	NC score	0.391890 (rank : 110)
Query Neighborhood Hits	225	Target Neighborhood Hits	194	Shared Neighborhood Hits	94
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA17_MOUSE
θ value	0.00509761 (rank : 117)	NC score	0.388669 (rank : 112)
Query Neighborhood Hits	225	Target Neighborhood Hits	201	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

WISP2_HUMAN
θ value	0.00665767 (rank : 118)	NC score	0.171985 (rank : 120)
Query Neighborhood Hits	225	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

ADA17_HUMAN
θ value	0.0113563 (rank : 119)	NC score	0.378180 (rank : 114)
Query Neighborhood Hits	225	Target Neighborhood Hits	223	Shared Neighborhood Hits	97
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA18_MOUSE
θ value	0.0148317 (rank : 120)	NC score	0.426235 (rank : 103)
Query Neighborhood Hits	225	Target Neighborhood Hits	227	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA10_HUMAN
θ value	0.0252991 (rank : 121)	NC score	0.390370 (rank : 111)
Query Neighborhood Hits	225	Target Neighborhood Hits	189	Shared Neighborhood Hits	97
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

SLIT1_MOUSE
θ value	0.0330416 (rank : 122)	NC score	0.024817 (rank : 247)
Query Neighborhood Hits	225	Target Neighborhood Hits	715	Shared Neighborhood Hits	73
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

LRP2_HUMAN
θ value	0.0431538 (rank : 123)	NC score	0.068670 (rank : 159)
Query Neighborhood Hits	225	Target Neighborhood Hits	573	Shared Neighborhood Hits	102
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

WISP2_MOUSE
θ value	0.0736092 (rank : 124)	NC score	0.170341 (rank : 121)
Query Neighborhood Hits	225	Target Neighborhood Hits	129	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

CILP1_MOUSE
θ value	0.0961366 (rank : 125)	NC score	0.290275 (rank : 119)
Query Neighborhood Hits	225	Target Neighborhood Hits	282	Shared Neighborhood Hits	82
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

FBN1_HUMAN
θ value	0.0961366 (rank : 126)	NC score	0.057624 (rank : 190)
Query Neighborhood Hits	225	Target Neighborhood Hits	557	Shared Neighborhood Hits	102
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FRAS1_HUMAN
θ value	0.125558 (rank : 127)	NC score	0.102503 (rank : 133)
Query Neighborhood Hits	225	Target Neighborhood Hits	759	Shared Neighborhood Hits	133
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF6_HUMAN
θ value	0.125558 (rank : 128)	NC score	0.069773 (rank : 158)
Query Neighborhood Hits	225	Target Neighborhood Hits	671	Shared Neighborhood Hits	129
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NOTC3_MOUSE
θ value	0.125558 (rank : 129)	NC score	0.059875 (rank : 176)
Query Neighborhood Hits	225	Target Neighborhood Hits	975	Shared Neighborhood Hits	114
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
θ value	0.163984 (rank : 130)	NC score	0.049211 (rank : 232)
Query Neighborhood Hits	225	Target Neighborhood Hits	872	Shared Neighborhood Hits	107
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

CYR61_HUMAN
θ value	0.21417 (rank : 131)	NC score	0.133324 (rank : 124)
Query Neighborhood Hits	225	Target Neighborhood Hits	159	Shared Neighborhood Hits	78
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

LASP1_HUMAN
θ value	0.21417 (rank : 132)	NC score	0.009323 (rank : 257)
Query Neighborhood Hits	225	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

RSPO1_HUMAN
θ value	0.21417 (rank : 133)	NC score	0.109578 (rank : 131)
Query Neighborhood Hits	225	Target Neighborhood Hits	101	Shared Neighborhood Hits	53
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

LASP1_MOUSE
θ value	0.279714 (rank : 134)	NC score	0.008953 (rank : 259)
Query Neighborhood Hits	225	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

WISP1_MOUSE
θ value	0.279714 (rank : 135)	NC score	0.147112 (rank : 122)
Query Neighborhood Hits	225	Target Neighborhood Hits	123	Shared Neighborhood Hits	63
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

CYR61_MOUSE
θ value	0.365318 (rank : 136)	NC score	0.118650 (rank : 127)
Query Neighborhood Hits	225	Target Neighborhood Hits	156	Shared Neighborhood Hits	71
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

RSPO4_HUMAN
θ value	0.365318 (rank : 137)	NC score	0.090901 (rank : 139)
Query Neighborhood Hits	225	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	0.365318 (rank : 138)	NC score	0.110527 (rank : 130)
Query Neighborhood Hits	225	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

LTBP2_HUMAN
θ value	0.47712 (rank : 139)	NC score	0.058259 (rank : 184)
Query Neighborhood Hits	225	Target Neighborhood Hits	552	Shared Neighborhood Hits	93
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	0.47712 (rank : 140)	NC score	0.050504 (rank : 228)
Query Neighborhood Hits	225	Target Neighborhood Hits	502	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

WFDC8_HUMAN
θ value	0.47712 (rank : 141)	NC score	0.016611 (rank : 250)
Query Neighborhood Hits	225	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

NOV_HUMAN
θ value	0.62314 (rank : 142)	NC score	0.112685 (rank : 129)
Query Neighborhood Hits	225	Target Neighborhood Hits	128	Shared Neighborhood Hits	60
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
θ value	0.62314 (rank : 143)	NC score	0.124751 (rank : 125)
Query Neighborhood Hits	225	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

I17RA_HUMAN
θ value	0.813845 (rank : 144)	NC score	0.011230 (rank : 256)
Query Neighborhood Hits	225	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q96F46, O43844	Gene names	IL17RA, IL17R
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

PHF12_MOUSE
θ value	0.813845 (rank : 145)	NC score	0.007869 (rank : 262)
Query Neighborhood Hits	225	Target Neighborhood Hits	172	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

RSPO1_MOUSE
θ value	0.813845 (rank : 146)	NC score	0.098396 (rank : 137)
Query Neighborhood Hits	225	Target Neighborhood Hits	85	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO3_HUMAN
θ value	0.813845 (rank : 147)	NC score	0.086635 (rank : 141)
Query Neighborhood Hits	225	Target Neighborhood Hits	128	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

WISP3_HUMAN
θ value	0.813845 (rank : 148)	NC score	0.120476 (rank : 126)
Query Neighborhood Hits	225	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

KRA98_HUMAN
θ value	1.06291 (rank : 149)	NC score	0.087558 (rank : 140)
Query Neighborhood Hits	225	Target Neighborhood Hits	185	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

RSPO2_MOUSE
θ value	1.06291 (rank : 150)	NC score	0.067932 (rank : 161)
Query Neighborhood Hits	225	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

ZN567_HUMAN
θ value	1.06291 (rank : 151)	NC score	-0.006580 (rank : 290)
Query Neighborhood Hits	225	Target Neighborhood Hits	769	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N184, Q6N044	Gene names	ZNF567
Domain Architecture	No domain graphic available
Description	Zinc finger protein 567.

MUC2_HUMAN
θ value	1.38821 (rank : 152)	NC score	0.034607 (rank : 242)
Query Neighborhood Hits	225	Target Neighborhood Hits	906	Shared Neighborhood Hits	58
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SREC2_HUMAN
θ value	1.38821 (rank : 153)	NC score	0.054379 (rank : 207)
Query Neighborhood Hits	225	Target Neighborhood Hits	645	Shared Neighborhood Hits	89
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

WISP1_HUMAN
θ value	1.38821 (rank : 154)	NC score	0.138348 (rank : 123)
Query Neighborhood Hits	225	Target Neighborhood Hits	121	Shared Neighborhood Hits	67
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

CJ086_HUMAN
θ value	1.81305 (rank : 155)	NC score	0.016352 (rank : 251)
Query Neighborhood Hits	225	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXX6, Q5SQQ5, Q6P673, Q8WY66, Q9BS90	Gene names	C10orf86
Domain Architecture	No domain graphic available
Description	Protein C10orf86.

CTGF_HUMAN
θ value	1.81305 (rank : 156)	NC score	0.098641 (rank : 136)
Query Neighborhood Hits	225	Target Neighborhood Hits	128	Shared Neighborhood Hits	59
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

FBLN2_MOUSE
θ value	1.81305 (rank : 157)	NC score	0.042172 (rank : 239)
Query Neighborhood Hits	225	Target Neighborhood Hits	505	Shared Neighborhood Hits	62
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LTB1L_MOUSE
θ value	1.81305 (rank : 158)	NC score	0.053107 (rank : 214)
Query Neighborhood Hits	225	Target Neighborhood Hits	514	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.81305 (rank : 159)	NC score	0.052291 (rank : 219)
Query Neighborhood Hits	225	Target Neighborhood Hits	479	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_MOUSE
θ value	1.81305 (rank : 160)	NC score	0.054981 (rank : 204)
Query Neighborhood Hits	225	Target Neighborhood Hits	475	Shared Neighborhood Hits	87
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CAH9_HUMAN
θ value	2.36792 (rank : 161)	NC score	0.002617 (rank : 278)
Query Neighborhood Hits	225	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q16790	Gene names	CA9, G250, MN
Domain Architecture
Description	Carbonic anhydrase 9 precursor (EC 4.2.1.1) (Carbonic anhydrase IX) (Carbonate dehydratase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC- associated antigen G250) (pMW1).

ITB6_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.030714 (rank : 245)
Query Neighborhood Hits	225	Target Neighborhood Hits	318	Shared Neighborhood Hits	70
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KRA93_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.080170 (rank : 150)
Query Neighborhood Hits	225	Target Neighborhood Hits	203	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

LRP1_HUMAN
θ value	2.36792 (rank : 164)	NC score	0.066764 (rank : 164)
Query Neighborhood Hits	225	Target Neighborhood Hits	617	Shared Neighborhood Hits	109
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LTBP2_MOUSE
θ value	2.36792 (rank : 165)	NC score	0.052946 (rank : 215)
Query Neighborhood Hits	225	Target Neighborhood Hits	617	Shared Neighborhood Hits	92
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

RSPO3_MOUSE
θ value	2.36792 (rank : 166)	NC score	0.079595 (rank : 151)
Query Neighborhood Hits	225	Target Neighborhood Hits	120	Shared Neighborhood Hits	44
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

SORL_HUMAN
θ value	2.36792 (rank : 167)	NC score	0.048222 (rank : 234)
Query Neighborhood Hits	225	Target Neighborhood Hits	440	Shared Neighborhood Hits	74
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SREC_HUMAN
θ value	2.36792 (rank : 168)	NC score	0.059741 (rank : 177)
Query Neighborhood Hits	225	Target Neighborhood Hits	645	Shared Neighborhood Hits	103
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ARI2_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.009103 (rank : 258)
Query Neighborhood Hits	225	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	3.0926 (rank : 170)	NC score	0.008181 (rank : 260)
Query Neighborhood Hits	225	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

FSTL1_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.014628 (rank : 252)
Query Neighborhood Hits	225	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	3.0926 (rank : 172)	NC score	0.014105 (rank : 253)
Query Neighborhood Hits	225	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

ITA8_HUMAN
θ value	3.0926 (rank : 173)	NC score	0.001706 (rank : 281)
Query Neighborhood Hits	225	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P53708, Q5VX94	Gene names	ITGA8
Domain Architecture
Description	Integrin alpha-8 precursor [Contains: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain].

IZUM1_HUMAN
θ value	3.0926 (rank : 174)	NC score	0.011288 (rank : 255)
Query Neighborhood Hits	225	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYV9, Q6Q8P6, Q6Q8P7	Gene names	IZUMO1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

KR106_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.106702 (rank : 132)
Query Neighborhood Hits	225	Target Neighborhood Hits	347	Shared Neighborhood Hits	90
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

MLL2_HUMAN
θ value	3.0926 (rank : 176)	NC score	0.005408 (rank : 269)
Query Neighborhood Hits	225	Target Neighborhood Hits	1788	Shared Neighborhood Hits	33
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PIPNB_HUMAN
θ value	3.0926 (rank : 177)	NC score	0.007009 (rank : 263)
Query Neighborhood Hits	225	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P48739, Q8N5W1	Gene names	PITPNB
Domain Architecture
Description	Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta).

ST14_HUMAN
θ value	3.0926 (rank : 178)	NC score	0.020529 (rank : 249)
Query Neighborhood Hits	225	Target Neighborhood Hits	409	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

TRI42_MOUSE
θ value	3.0926 (rank : 179)	NC score	0.004704 (rank : 270)
Query Neighborhood Hits	225	Target Neighborhood Hits	316	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

VLDLR_MOUSE
θ value	3.0926 (rank : 180)	NC score	0.047024 (rank : 235)
Query Neighborhood Hits	225	Target Neighborhood Hits	360	Shared Neighborhood Hits	75
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ZFP11_MOUSE
θ value	3.0926 (rank : 181)	NC score	-0.006742 (rank : 291)
Query Neighborhood Hits	225	Target Neighborhood Hits	763	Shared Neighborhood Hits	12
SwissProt Accessions	P10751, Q505E4, Q6PDR5, Q8BSI2, Q8C3R5	Gene names	Zfp11, Krox-6.1a
Domain Architecture	No domain graphic available
Description	Zinc finger protein 11 (Zfp-11) (Krox-6.1A protein).

ZNFX1_MOUSE
θ value	3.0926 (rank : 182)	NC score	0.022130 (rank : 248)
Query Neighborhood Hits	225	Target Neighborhood Hits	407	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

IRAK3_HUMAN
θ value	4.03905 (rank : 183)	NC score	-0.005213 (rank : 287)
Query Neighborhood Hits	225	Target Neighborhood Hits	644	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

MEGF8_HUMAN
θ value	4.03905 (rank : 184)	NC score	0.037380 (rank : 240)
Query Neighborhood Hits	225	Target Neighborhood Hits	528	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

PIPNB_MOUSE
θ value	4.03905 (rank : 185)	NC score	0.006565 (rank : 265)
Query Neighborhood Hits	225	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P53811	Gene names	Pitpnb
Domain Architecture
Description	Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta).

RSPO2_HUMAN
θ value	4.03905 (rank : 186)	NC score	0.073216 (rank : 156)
Query Neighborhood Hits	225	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

TCGAP_HUMAN
θ value	4.03905 (rank : 187)	NC score	0.000588 (rank : 283)
Query Neighborhood Hits	225	Target Neighborhood Hits	872	Shared Neighborhood Hits	12
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ACINU_MOUSE
θ value	5.27518 (rank : 188)	NC score	0.001145 (rank : 282)
Query Neighborhood Hits	225	Target Neighborhood Hits	712	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

APOA_HUMAN
θ value	5.27518 (rank : 189)	NC score	0.002993 (rank : 275)
Query Neighborhood Hits	225	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

C1QR1_MOUSE
θ value	5.27518 (rank : 190)	NC score	0.034119 (rank : 243)
Query Neighborhood Hits	225	Target Neighborhood Hits	342	Shared Neighborhood Hits	46
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CTGF_MOUSE
θ value	5.27518 (rank : 191)	NC score	0.102326 (rank : 134)
Query Neighborhood Hits	225	Target Neighborhood Hits	124	Shared Neighborhood Hits	57
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

HNF1B_HUMAN
θ value	5.27518 (rank : 192)	NC score	0.005987 (rank : 267)
Query Neighborhood Hits	225	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	P35680	Gene names	TCF2, HNF1B
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2).

MRP7_MOUSE
θ value	5.27518 (rank : 193)	NC score	-0.000435 (rank : 285)
Query Neighborhood Hits	225	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

UBP54_HUMAN
θ value	5.27518 (rank : 194)	NC score	0.004593 (rank : 272)
Query Neighborhood Hits	225	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

VLDLR_HUMAN
θ value	5.27518 (rank : 195)	NC score	0.046274 (rank : 236)
Query Neighborhood Hits	225	Target Neighborhood Hits	383	Shared Neighborhood Hits	75
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ZN432_HUMAN
θ value	5.27518 (rank : 196)	NC score	-0.007012 (rank : 293)
Query Neighborhood Hits	225	Target Neighborhood Hits	764	Shared Neighborhood Hits	10
SwissProt Accessions	O94892	Gene names	ZNF432, KIAA0798
Domain Architecture
Description	Zinc finger protein 432.

ZNF81_HUMAN
θ value	5.27518 (rank : 197)	NC score	-0.007048 (rank : 294)
Query Neighborhood Hits	225	Target Neighborhood Hits	786	Shared Neighborhood Hits	13
SwissProt Accessions	P51508, Q6RX22, Q96QH6	Gene names	ZNF81
Domain Architecture	No domain graphic available
Description	Zinc finger protein 81 (HFZ20).

CFAH_HUMAN
θ value	6.88961 (rank : 198)	NC score	0.007961 (rank : 261)
Query Neighborhood Hits	225	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

DOK1_HUMAN
θ value	6.88961 (rank : 199)	NC score	0.002826 (rank : 276)
Query Neighborhood Hits	225	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

HNF1B_MOUSE
θ value	6.88961 (rank : 200)	NC score	0.005457 (rank : 268)
Query Neighborhood Hits	225	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

ICAM5_MOUSE
θ value	6.88961 (rank : 201)	NC score	0.013256 (rank : 254)
Query Neighborhood Hits	225	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

LRP1B_MOUSE
θ value	6.88961 (rank : 202)	NC score	0.063561 (rank : 167)
Query Neighborhood Hits	225	Target Neighborhood Hits	606	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP4_MOUSE
θ value	6.88961 (rank : 203)	NC score	0.050307 (rank : 230)
Query Neighborhood Hits	225	Target Neighborhood Hits	351	Shared Neighborhood Hits	76
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

NU133_HUMAN
θ value	6.88961 (rank : 204)	NC score	0.004654 (rank : 271)
Query Neighborhood Hits	225	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

RASF5_HUMAN
θ value	6.88961 (rank : 205)	NC score	0.002558 (rank : 279)
Query Neighborhood Hits	225	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

SORL_MOUSE
θ value	6.88961 (rank : 206)	NC score	0.042847 (rank : 238)
Query Neighborhood Hits	225	Target Neighborhood Hits	439	Shared Neighborhood Hits	70
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TF3C4_MOUSE
θ value	6.88961 (rank : 207)	NC score	0.006945 (rank : 264)
Query Neighborhood Hits	225	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMQ2, Q8BKZ4	Gene names	Gtf3c4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

ZN224_HUMAN
θ value	6.88961 (rank : 208)	NC score	-0.006935 (rank : 292)
Query Neighborhood Hits	225	Target Neighborhood Hits	808	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZL3, Q86V10, Q8IZC8, Q9UID9, Q9Y2P6	Gene names	ZNF224, BMZF2, ZNF255
Domain Architecture
Description	Zinc finger protein 224 (Zinc finger protein 255) (Bone marrow zinc finger 2) (BMZF-2).

ZN746_HUMAN
θ value	6.88961 (rank : 209)	NC score	-0.005991 (rank : 288)
Query Neighborhood Hits	225	Target Neighborhood Hits	745	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

AT1B2_HUMAN
θ value	8.99809 (rank : 210)	NC score	0.001980 (rank : 280)
Query Neighborhood Hits	225	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P14415, O60444	Gene names	ATP1B2
Domain Architecture
Description	Sodium/potassium-transporting ATPase subunit beta-2 (Sodium/potassium- dependent ATPase beta-2 subunit).

CELR2_MOUSE
θ value	8.99809 (rank : 211)	NC score	0.026458 (rank : 246)
Query Neighborhood Hits	225	Target Neighborhood Hits	584	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

EGF_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.031598 (rank : 244)
Query Neighborhood Hits	225	Target Neighborhood Hits	343	Shared Neighborhood Hits	49
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

KR101_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.071269 (rank : 157)
Query Neighborhood Hits	225	Target Neighborhood Hits	261	Shared Neighborhood Hits	70
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

LAP2A_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.003058 (rank : 274)
Query Neighborhood Hits	225	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

LRP8_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.048574 (rank : 233)
Query Neighborhood Hits	225	Target Neighborhood Hits	385	Shared Neighborhood Hits	76
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MEGF8_MOUSE
θ value	8.99809 (rank : 216)	NC score	0.037280 (rank : 241)
Query Neighborhood Hits	225	Target Neighborhood Hits	520	Shared Neighborhood Hits	69
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MUC5B_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.046127 (rank : 237)
Query Neighborhood Hits	225	Target Neighborhood Hits	1020	Shared Neighborhood Hits	78
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NFX1_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.067728 (rank : 163)
Query Neighborhood Hits	225	Target Neighborhood Hits	405	Shared Neighborhood Hits	59
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NR1H3_HUMAN
θ value	8.99809 (rank : 219)	NC score	-0.002058 (rank : 286)
Query Neighborhood Hits	225	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

SASH1_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.002713 (rank : 277)
Query Neighborhood Hits	225	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

TF3C4_HUMAN
θ value	8.99809 (rank : 221)	NC score	0.006298 (rank : 266)
Query Neighborhood Hits	225	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKN8	Gene names	GTF3C4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

TF7L2_MOUSE
θ value	8.99809 (rank : 222)	NC score	0.000349 (rank : 284)
Query Neighborhood Hits	225	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TRI42_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.003755 (rank : 273)
Query Neighborhood Hits	225	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ZN672_HUMAN
θ value	8.99809 (rank : 224)	NC score	-0.007284 (rank : 295)
Query Neighborhood Hits	225	Target Neighborhood Hits	744	Shared Neighborhood Hits	10
SwissProt Accessions	Q499Z4, Q96H65, Q96IM3, Q9H6G5	Gene names	ZNF672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.

ZN746_MOUSE
θ value	8.99809 (rank : 225)	NC score	-0.006489 (rank : 289)
Query Neighborhood Hits	225	Target Neighborhood Hits	748	Shared Neighborhood Hits	10
SwissProt Accessions	Q3U133	Gene names	Znf746, Zfp746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

C1QR1_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.052345 (rank : 217)
Query Neighborhood Hits	225	Target Neighborhood Hits	493	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CD97_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.052302 (rank : 218)
Query Neighborhood Hits	225	Target Neighborhood Hits	295	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CO9_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.068482 (rank : 160)
Query Neighborhood Hits	225	Target Neighborhood Hits	147	Shared Neighborhood Hits	29
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.076206 (rank : 153)
Query Neighborhood Hits	225	Target Neighborhood Hits	153	Shared Neighborhood Hits	38
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.061288 (rank : 171)
Query Neighborhood Hits	225	Target Neighborhood Hits	258	Shared Neighborhood Hits	43
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.059899 (rank : 175)
Query Neighborhood Hits	225	Target Neighborhood Hits	290	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRIM1_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.063258 (rank : 169)
Query Neighborhood Hits	225	Target Neighborhood Hits	362	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

DLL1_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.051826 (rank : 222)
Query Neighborhood Hits	225	Target Neighborhood Hits	455	Shared Neighborhood Hits	91
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.055693 (rank : 200)
Query Neighborhood Hits	225	Target Neighborhood Hits	456	Shared Neighborhood Hits	93
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

ELTD1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.051469 (rank : 224)
Query Neighborhood Hits	225	Target Neighborhood Hits	269	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.050477 (rank : 229)
Query Neighborhood Hits	225	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.050915 (rank : 227)
Query Neighborhood Hits	225	Target Neighborhood Hits	382	Shared Neighborhood Hits	54
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.051160 (rank : 225)
Query Neighborhood Hits	225	Target Neighborhood Hits	349	Shared Neighborhood Hits	51
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

FBN1_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.054880 (rank : 205)
Query Neighborhood Hits	225	Target Neighborhood Hits	563	Shared Neighborhood Hits	102
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.056179 (rank : 199)
Query Neighborhood Hits	225	Target Neighborhood Hits	560	Shared Neighborhood Hits	107
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.057260 (rank : 193)
Query Neighborhood Hits	225	Target Neighborhood Hits	549	Shared Neighborhood Hits	108
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.052524 (rank : 216)
Query Neighborhood Hits	225	Target Neighborhood Hits	543	Shared Neighborhood Hits	100
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

JAG1_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.057253 (rank : 194)
Query Neighborhood Hits	225	Target Neighborhood Hits	514	Shared Neighborhood Hits	99
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.056182 (rank : 198)
Query Neighborhood Hits	225	Target Neighborhood Hits	518	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.057700 (rank : 187)
Query Neighborhood Hits	225	Target Neighborhood Hits	491	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.058328 (rank : 183)
Query Neighborhood Hits	225	Target Neighborhood Hits	504	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR102_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.086543 (rank : 142)
Query Neighborhood Hits	225	Target Neighborhood Hits	264	Shared Neighborhood Hits	71
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.102048 (rank : 135)
Query Neighborhood Hits	225	Target Neighborhood Hits	313	Shared Neighborhood Hits	80
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.059194 (rank : 178)
Query Neighborhood Hits	225	Target Neighborhood Hits	271	Shared Neighborhood Hits	61
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR107_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.086454 (rank : 143)
Query Neighborhood Hits	225	Target Neighborhood Hits	330	Shared Neighborhood Hits	82
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR109_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.062487 (rank : 170)
Query Neighborhood Hits	225	Target Neighborhood Hits	226	Shared Neighborhood Hits	57
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.060346 (rank : 172)
Query Neighborhood Hits	225	Target Neighborhood Hits	269	Shared Neighborhood Hits	64
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.059070 (rank : 180)
Query Neighborhood Hits	225	Target Neighborhood Hits	219	Shared Neighborhood Hits	58
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR412_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.055487 (rank : 201)
Query Neighborhood Hits	225	Target Neighborhood Hits	178	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.054344 (rank : 208)
Query Neighborhood Hits	225	Target Neighborhood Hits	199	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.053716 (rank : 212)
Query Neighborhood Hits	225	Target Neighborhood Hits	217	Shared Neighborhood Hits	49
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA51_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.083915 (rank : 144)
Query Neighborhood Hits	225	Target Neighborhood Hits	288	Shared Neighborhood Hits	80
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.065997 (rank : 165)
Query Neighborhood Hits	225	Target Neighborhood Hits	236	Shared Neighborhood Hits	60
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.080380 (rank : 148)
Query Neighborhood Hits	225	Target Neighborhood Hits	331	Shared Neighborhood Hits	86
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.074282 (rank : 155)
Query Neighborhood Hits	225	Target Neighborhood Hits	270	Shared Neighborhood Hits	69
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA57_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.074981 (rank : 154)
Query Neighborhood Hits	225	Target Neighborhood Hits	269	Shared Neighborhood Hits	69
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.081974 (rank : 146)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	81
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.059923 (rank : 174)
Query Neighborhood Hits	225	Target Neighborhood Hits	310	Shared Neighborhood Hits	70
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.078517 (rank : 152)
Query Neighborhood Hits	225	Target Neighborhood Hits	198	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA94_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.053360 (rank : 213)
Query Neighborhood Hits	225	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA99_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.054424 (rank : 206)
Query Neighborhood Hits	225	Target Neighborhood Hits	173	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LDLR_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.054255 (rank : 210)
Query Neighborhood Hits	225	Target Neighborhood Hits	375	Shared Neighborhood Hits	82
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.067920 (rank : 162)
Query Neighborhood Hits	225	Target Neighborhood Hits	602	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LTB1L_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.052260 (rank : 220)
Query Neighborhood Hits	225	Target Neighborhood Hits	553	Shared Neighborhood Hits	89
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.051806 (rank : 223)
Query Neighborhood Hits	225	Target Neighborhood Hits	502	Shared Neighborhood Hits	86
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MT1B_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.054065 (rank : 211)
Query Neighborhood Hits	225	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

NAGPA_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.054276 (rank : 209)
Query Neighborhood Hits	225	Target Neighborhood Hits	308	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.052200 (rank : 221)
Query Neighborhood Hits	225	Target Neighborhood Hits	451	Shared Neighborhood Hits	81
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.059127 (rank : 179)
Query Neighborhood Hits	225	Target Neighborhood Hits	449	Shared Neighborhood Hits	87
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.057829 (rank : 185)
Query Neighborhood Hits	225	Target Neighborhood Hits	436	Shared Neighborhood Hits	86
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NOTC1_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.060258 (rank : 173)
Query Neighborhood Hits	225	Target Neighborhood Hits	906	Shared Neighborhood Hits	114
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.056634 (rank : 196)
Query Neighborhood Hits	225	Target Neighborhood Hits	916	Shared Neighborhood Hits	104
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.057268 (rank : 192)
Query Neighborhood Hits	225	Target Neighborhood Hits	1113	Shared Neighborhood Hits	113
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.057172 (rank : 195)
Query Neighborhood Hits	225	Target Neighborhood Hits	1069	Shared Neighborhood Hits	106
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.057686 (rank : 189)
Query Neighborhood Hits	225	Target Neighborhood Hits	1062	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PCSK5_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.063491 (rank : 168)
Query Neighborhood Hits	225	Target Neighborhood Hits	613	Shared Neighborhood Hits	107
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

RELN_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.055474 (rank : 202)
Query Neighborhood Hits	225	Target Neighborhood Hits	233	Shared Neighborhood Hits	51
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.057733 (rank : 186)
Query Neighborhood Hits	225	Target Neighborhood Hits	235	Shared Neighborhood Hits	53
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

SPON2_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.094546 (rank : 138)
Query Neighborhood Hits	225	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON2_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.081450 (rank : 147)
Query Neighborhood Hits	225	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

SREC2_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.057686 (rank : 188)
Query Neighborhood Hits	225	Target Neighborhood Hits	605	Shared Neighborhood Hits	95
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

STAB2_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.051096 (rank : 226)
Query Neighborhood Hits	225	Target Neighborhood Hits	528	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TENA_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.058897 (rank : 181)
Query Neighborhood Hits	225	Target Neighborhood Hits	631	Shared Neighborhood Hits	98
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.063791 (rank : 166)
Query Neighborhood Hits	225	Target Neighborhood Hits	596	Shared Neighborhood Hits	93
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TSP3_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.058859 (rank : 182)
Query Neighborhood Hits	225	Target Neighborhood Hits	250	Shared Neighborhood Hits	39
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.057382 (rank : 191)
Query Neighborhood Hits	225	Target Neighborhood Hits	247	Shared Neighborhood Hits	36
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.056227 (rank : 197)
Query Neighborhood Hits	225	Target Neighborhood Hits	277	Shared Neighborhood Hits	37
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.055286 (rank : 203)
Query Neighborhood Hits	225	Target Neighborhood Hits	276	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

WIF1_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.050151 (rank : 231)
Query Neighborhood Hits	225	Target Neighborhood Hits	393	Shared Neighborhood Hits	78
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ZAN_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.080184 (rank : 149)
Query Neighborhood Hits	225	Target Neighborhood Hits	808	Shared Neighborhood Hits	122
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

ATS20_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	225
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_HUMAN
NC score	0.994178 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	225	Target Neighborhood Hits	192	Shared Neighborhood Hits	150
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS9_HUMAN
NC score	0.992210 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	225	Target Neighborhood Hits	219	Shared Neighborhood Hits	157
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS15_HUMAN
NC score	0.980648 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	225	Target Neighborhood Hits	151	Shared Neighborhood Hits	134
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS1_MOUSE
NC score	0.978555 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	225	Target Neighborhood Hits	158	Shared Neighborhood Hits	138
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS1_HUMAN
NC score	0.977891 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	225	Target Neighborhood Hits	159	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS8_HUMAN
NC score	0.973740 (rank : 7)	θ value	7.7336e-177 (rank : 7)
Query Neighborhood Hits	225	Target Neighborhood Hits	145	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS18_MOUSE
NC score	0.973291 (rank : 8)	θ value	5.19945e-165 (rank : 9)
Query Neighborhood Hits	225	Target Neighborhood Hits	163	Shared Neighborhood Hits	134
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_HUMAN
NC score	0.972730 (rank : 9)	θ value	5.74867e-164 (rank : 10)
Query Neighborhood Hits	225	Target Neighborhood Hits	169	Shared Neighborhood Hits	134
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS5_MOUSE
NC score	0.972301 (rank : 10)	θ value	1.91371e-159 (rank : 13)
Query Neighborhood Hits	225	Target Neighborhood Hits	147	Shared Neighborhood Hits	127
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS16_MOUSE
NC score	0.971113 (rank : 11)	θ value	1.85358e-154 (rank : 16)
Query Neighborhood Hits	225	Target Neighborhood Hits	179	Shared Neighborhood Hits	142
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_HUMAN
NC score	0.969902 (rank : 12)	θ value	1.79534e-149 (rank : 18)
Query Neighborhood Hits	225	Target Neighborhood Hits	208	Shared Neighborhood Hits	142
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS5_HUMAN
NC score	0.969660 (rank : 13)	θ value	5.03607e-160 (rank : 12)
Query Neighborhood Hits	225	Target Neighborhood Hits	141	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS7_HUMAN
NC score	0.969454 (rank : 14)	θ value	2.06368e-129 (rank : 20)
Query Neighborhood Hits	225	Target Neighborhood Hits	169	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS12_MOUSE
NC score	0.969349 (rank : 15)	θ value	2.18956e-155 (rank : 15)
Query Neighborhood Hits	225	Target Neighborhood Hits	220	Shared Neighborhood Hits	138
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS8_MOUSE
NC score	0.968716 (rank : 16)	θ value	1.23469e-174 (rank : 8)
Query Neighborhood Hits	225	Target Neighborhood Hits	139	Shared Neighborhood Hits	122
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS12_HUMAN
NC score	0.967907 (rank : 17)	θ value	1.24331e-150 (rank : 17)
Query Neighborhood Hits	225	Target Neighborhood Hits	251	Shared Neighborhood Hits	138
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS6_HUMAN
NC score	0.966296 (rank : 18)	θ value	9.26343e-130 (rank : 19)
Query Neighborhood Hits	225	Target Neighborhood Hits	141	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS17_HUMAN
NC score	0.965980 (rank : 19)	θ value	9.58617e-127 (rank : 21)
Query Neighborhood Hits	225	Target Neighborhood Hits	194	Shared Neighborhood Hits	139
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS3_HUMAN
NC score	0.963345 (rank : 20)	θ value	5.26011e-125 (rank : 23)
Query Neighborhood Hits	225	Target Neighborhood Hits	179	Shared Neighborhood Hits	142
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS2_HUMAN
NC score	0.961767 (rank : 21)	θ value	2.78914e-126 (rank : 22)
Query Neighborhood Hits	225	Target Neighborhood Hits	179	Shared Neighborhood Hits	132
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS4_MOUSE
NC score	0.961145 (rank : 22)	θ value	7.508e-164 (rank : 11)
Query Neighborhood Hits	225	Target Neighborhood Hits	145	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS2_MOUSE
NC score	0.960149 (rank : 23)	θ value	1.99884e-124 (rank : 24)
Query Neighborhood Hits	225	Target Neighborhood Hits	179	Shared Neighborhood Hits	127
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS4_HUMAN
NC score	0.959836 (rank : 24)	θ value	5.56804e-159 (rank : 14)
Query Neighborhood Hits	225	Target Neighborhood Hits	138	Shared Neighborhood Hits	115
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS19_MOUSE
NC score	0.958626 (rank : 25)	θ value	5.44333e-122 (rank : 26)
Query Neighborhood Hits	225	Target Neighborhood Hits	188	Shared Neighborhood Hits	132
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_HUMAN
NC score	0.957430 (rank : 26)	θ value	4.45295e-124 (rank : 25)
Query Neighborhood Hits	225	Target Neighborhood Hits	203	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS14_HUMAN
NC score	0.953390 (rank : 27)	θ value	1.30163e-107 (rank : 29)
Query Neighborhood Hits	225	Target Neighborhood Hits	382	Shared Neighborhood Hits	133
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS13_HUMAN
NC score	0.933544 (rank : 28)	θ value	2.70778e-113 (rank : 27)
Query Neighborhood Hits	225	Target Neighborhood Hits	238	Shared Neighborhood Hits	123
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
NC score	0.927488 (rank : 29)	θ value	1.39067e-109 (rank : 28)
Query Neighborhood Hits	225	Target Neighborhood Hits	227	Shared Neighborhood Hits	127
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL1_HUMAN
NC score	0.886967 (rank : 30)	θ value	3.25095e-58 (rank : 31)
Query Neighborhood Hits	225	Target Neighborhood Hits	93	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL5_HUMAN
NC score	0.886541 (rank : 31)	θ value	1.01765e-35 (rank : 35)
Query Neighborhood Hits	225	Target Neighborhood Hits	103	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL1_MOUSE
NC score	0.877659 (rank : 32)	θ value	2.58786e-39 (rank : 34)
Query Neighborhood Hits	225	Target Neighborhood Hits	80	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL2_MOUSE
NC score	0.858891 (rank : 33)	θ value	2.04573e-44 (rank : 32)
Query Neighborhood Hits	225	Target Neighborhood Hits	137	Shared Neighborhood Hits	94
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL2_HUMAN
NC score	0.858256 (rank : 34)	θ value	1.73182e-43 (rank : 33)
Query Neighborhood Hits	225	Target Neighborhood Hits	125	Shared Neighborhood Hits	92
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL3_HUMAN
NC score	0.756771 (rank : 35)	θ value	1.40038e-85 (rank : 30)
Query Neighborhood Hits	225	Target Neighborhood Hits	414	Shared Neighborhood Hits	101
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

PROP_HUMAN
NC score	0.654479 (rank : 36)	θ value	2.7842e-17 (rank : 60)
Query Neighborhood Hits	225	Target Neighborhood Hits	126	Shared Neighborhood Hits	93
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
NC score	0.649002 (rank : 37)	θ value	7.58209e-15 (rank : 75)
Query Neighborhood Hits	225	Target Neighborhood Hits	165	Shared Neighborhood Hits	95
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SPON1_HUMAN
NC score	0.607461 (rank : 38)	θ value	3.51386e-20 (rank : 47)
Query Neighborhood Hits	225	Target Neighborhood Hits	117	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
NC score	0.606016 (rank : 39)	θ value	2.27762e-19 (rank : 50)
Query Neighborhood Hits	225	Target Neighborhood Hits	123	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

ADAM8_HUMAN
NC score	0.595555 (rank : 40)	θ value	6.84181e-24 (rank : 41)
Query Neighborhood Hits	225	Target Neighborhood Hits	327	Shared Neighborhood Hits	106
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA28_MOUSE
NC score	0.591999 (rank : 41)	θ value	5.06226e-27 (rank : 37)
Query Neighborhood Hits	225	Target Neighborhood Hits	241	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADAM8_MOUSE
NC score	0.591101 (rank : 42)	θ value	1.16704e-23 (rank : 42)
Query Neighborhood Hits	225	Target Neighborhood Hits	326	Shared Neighborhood Hits	110
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADA19_MOUSE
NC score	0.590971 (rank : 43)	θ value	5.06226e-27 (rank : 36)
Query Neighborhood Hits	225	Target Neighborhood Hits	315	Shared Neighborhood Hits	114
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA28_HUMAN
NC score	0.583195 (rank : 44)	θ value	4.01107e-24 (rank : 40)
Query Neighborhood Hits	225	Target Neighborhood Hits	244	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA19_HUMAN
NC score	0.582377 (rank : 45)	θ value	2.51237e-26 (rank : 39)
Query Neighborhood Hits	225	Target Neighborhood Hits	381	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADEC1_HUMAN
NC score	0.576598 (rank : 46)	θ value	3.07829e-16 (rank : 63)
Query Neighborhood Hits	225	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA33_HUMAN
NC score	0.575329 (rank : 47)	θ value	4.15078e-21 (rank : 45)
Query Neighborhood Hits	225	Target Neighborhood Hits	264	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA12_HUMAN
NC score	0.573377 (rank : 48)	θ value	1.5773e-20 (rank : 46)
Query Neighborhood Hits	225	Target Neighborhood Hits	224	Shared Neighborhood Hits	99
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CI094_HUMAN
NC score	0.571617 (rank : 49)	θ value	1.47289e-26 (rank : 38)
Query Neighborhood Hits	225	Target Neighborhood Hits	310	Shared Neighborhood Hits	78
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ADA12_MOUSE
NC score	0.563596 (rank : 50)	θ value	9.56915e-18 (rank : 56)
Query Neighborhood Hits	225	Target Neighborhood Hits	474	Shared Neighborhood Hits	104
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM7_HUMAN
NC score	0.557517 (rank : 51)	θ value	1.24977e-17 (rank : 58)
Query Neighborhood Hits	225	Target Neighborhood Hits	221	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
NC score	0.554222 (rank : 52)	θ value	3.63628e-17 (rank : 61)
Query Neighborhood Hits	225	Target Neighborhood Hits	200	Shared Neighborhood Hits	96
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM9_MOUSE
NC score	0.550351 (rank : 53)	θ value	9.56915e-18 (rank : 57)
Query Neighborhood Hits	225	Target Neighborhood Hits	325	Shared Neighborhood Hits	105
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA33_MOUSE
NC score	0.548865 (rank : 54)	θ value	6.62687e-19 (rank : 52)
Query Neighborhood Hits	225	Target Neighborhood Hits	231	Shared Neighborhood Hits	97
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA15_HUMAN
NC score	0.547669 (rank : 55)	θ value	4.30538e-10 (rank : 84)
Query Neighborhood Hits	225	Target Neighborhood Hits	288	Shared Neighborhood Hits	108
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADAM9_HUMAN
NC score	0.540080 (rank : 56)	θ value	3.28887e-18 (rank : 54)
Query Neighborhood Hits	225	Target Neighborhood Hits	243	Shared Neighborhood Hits	100
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADEC1_MOUSE
NC score	0.526919 (rank : 57)	θ value	1.2105e-12 (rank : 79)
Query Neighborhood Hits	225	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA15_MOUSE
NC score	0.517685 (rank : 58)	θ value	1.53129e-07 (rank : 91)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	110
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA22_HUMAN
NC score	0.517103 (rank : 59)	θ value	3.40345e-15 (rank : 66)
Query Neighborhood Hits	225	Target Neighborhood Hits	211	Shared Neighborhood Hits	96
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADM1B_MOUSE
NC score	0.513313 (rank : 60)	θ value	5.08577e-11 (rank : 82)
Query Neighborhood Hits	225	Target Neighborhood Hits	236	Shared Neighborhood Hits	104
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA23_MOUSE
NC score	0.509552 (rank : 61)	θ value	7.58209e-15 (rank : 72)
Query Neighborhood Hits	225	Target Neighborhood Hits	245	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

THSD1_HUMAN
NC score	0.507255 (rank : 62)	θ value	0.00035302 (rank : 114)
Query Neighborhood Hits	225	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA21_MOUSE
NC score	0.506727 (rank : 63)	θ value	1.09485e-13 (rank : 78)
Query Neighborhood Hits	225	Target Neighborhood Hits	172	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADM1A_MOUSE
NC score	0.506678 (rank : 64)	θ value	6.00763e-12 (rank : 80)
Query Neighborhood Hits	225	Target Neighborhood Hits	230	Shared Neighborhood Hits	107
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA22_MOUSE
NC score	0.505958 (rank : 65)	θ value	8.38298e-14 (rank : 77)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
NC score	0.502773 (rank : 66)	θ value	1.52774e-15 (rank : 64)
Query Neighborhood Hits	225	Target Neighborhood Hits	235	Shared Neighborhood Hits	100
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
NC score	0.499594 (rank : 67)	θ value	1.25267e-09 (rank : 86)
Query Neighborhood Hits	225	Target Neighborhood Hits	230	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
NC score	0.490585 (rank : 68)	θ value	2.21117e-06 (rank : 102)
Query Neighborhood Hits	225	Target Neighborhood Hits	213	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA29_HUMAN
NC score	0.490523 (rank : 69)	θ value	8.97725e-08 (rank : 90)
Query Neighborhood Hits	225	Target Neighborhood Hits	247	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA21_HUMAN
NC score	0.490401 (rank : 70)	θ value	6.64225e-11 (rank : 83)
Query Neighborhood Hits	225	Target Neighborhood Hits	181	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA11_MOUSE
NC score	0.490176 (rank : 71)	θ value	3.40345e-15 (rank : 65)
Query Neighborhood Hits	225	Target Neighborhood Hits	263	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

AD26A_MOUSE
NC score	0.488050 (rank : 72)	θ value	3.89403e-11 (rank : 81)
Query Neighborhood Hits	225	Target Neighborhood Hits	165	Shared Neighborhood Hits	92
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

TSP1_HUMAN
NC score	0.482599 (rank : 73)	θ value	4.44505e-15 (rank : 67)
Query Neighborhood Hits	225	Target Neighborhood Hits	389	Shared Neighborhood Hits	131
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.481906 (rank : 74)	θ value	4.44505e-15 (rank : 68)
Query Neighborhood Hits	225	Target Neighborhood Hits	396	Shared Neighborhood Hits	133
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

BAI1_MOUSE
NC score	0.479823 (rank : 75)	θ value	3.28887e-18 (rank : 55)
Query Neighborhood Hits	225	Target Neighborhood Hits	340	Shared Neighborhood Hits	94
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
NC score	0.479069 (rank : 76)	θ value	2.27762e-19 (rank : 49)
Query Neighborhood Hits	225	Target Neighborhood Hits	332	Shared Neighborhood Hits	100
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI1_HUMAN
NC score	0.478469 (rank : 77)	θ value	3.88503e-19 (rank : 51)
Query Neighborhood Hits	225	Target Neighborhood Hits	375	Shared Neighborhood Hits	97
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

THSD1_MOUSE
NC score	0.477746 (rank : 78)	θ value	5.44631e-05 (rank : 110)
Query Neighborhood Hits	225	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TSP2_MOUSE
NC score	0.477449 (rank : 79)	θ value	5.8054e-15 (rank : 71)
Query Neighborhood Hits	225	Target Neighborhood Hits	352	Shared Neighborhood Hits	123
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

BAI2_MOUSE
NC score	0.476689 (rank : 80)	θ value	1.33526e-19 (rank : 48)
Query Neighborhood Hits	225	Target Neighborhood Hits	323	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_MOUSE
NC score	0.475337 (rank : 81)	θ value	7.58209e-15 (rank : 74)
Query Neighborhood Hits	225	Target Neighborhood Hits	250	Shared Neighborhood Hits	101
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TSP2_HUMAN
NC score	0.475116 (rank : 82)	θ value	5.8054e-15 (rank : 70)
Query Neighborhood Hits	225	Target Neighborhood Hits	359	Shared Neighborhood Hits	125
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

BAI3_HUMAN
NC score	0.474683 (rank : 83)	θ value	7.58209e-15 (rank : 73)
Query Neighborhood Hits	225	Target Neighborhood Hits	246	Shared Neighborhood Hits	95
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

UNC5A_MOUSE
NC score	0.468870 (rank : 84)	θ value	6.21693e-09 (rank : 88)
Query Neighborhood Hits	225	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ADA11_HUMAN
NC score	0.467373 (rank : 85)	θ value	5.8054e-15 (rank : 69)
Query Neighborhood Hits	225	Target Neighborhood Hits	259	Shared Neighborhood Hits	101
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

UNC5B_MOUSE
NC score	0.457513 (rank : 86)	θ value	1.53129e-07 (rank : 93)
Query Neighborhood Hits	225	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
NC score	0.455191 (rank : 87)	θ value	1.53129e-07 (rank : 92)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

ADAM2_MOUSE
NC score	0.453315 (rank : 88)	θ value	1.63604e-09 (rank : 87)
Query Neighborhood Hits	225	Target Neighborhood Hits	209	Shared Neighborhood Hits	100
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

SSPO_MOUSE
NC score	0.450653 (rank : 89)	θ value	3.75424e-22 (rank : 44)
Query Neighborhood Hits	225	Target Neighborhood Hits	800	Shared Neighborhood Hits	173
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ADA32_HUMAN
NC score	0.447704 (rank : 90)	θ value	5.62301e-10 (rank : 85)
Query Neighborhood Hits	225	Target Neighborhood Hits	216	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA20_HUMAN
NC score	0.446608 (rank : 91)	θ value	0.00020696 (rank : 113)
Query Neighborhood Hits	225	Target Neighborhood Hits	143	Shared Neighborhood Hits	84
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA32_MOUSE
NC score	0.443600 (rank : 92)	θ value	8.40245e-06 (rank : 103)
Query Neighborhood Hits	225	Target Neighborhood Hits	219	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

SEM5A_HUMAN
NC score	0.442723 (rank : 93)	θ value	1.63225e-17 (rank : 59)
Query Neighborhood Hits	225	Target Neighborhood Hits	177	Shared Neighborhood Hits	97
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

UNC5C_MOUSE
NC score	0.440938 (rank : 94)	θ value	7.59969e-07 (rank : 100)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.440406 (rank : 95)	θ value	7.59969e-07 (rank : 99)
Query Neighborhood Hits	225	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

CO8A_HUMAN
NC score	0.433390 (rank : 96)	θ value	2.36244e-08 (rank : 89)
Query Neighborhood Hits	225	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

SEM5A_MOUSE
NC score	0.433203 (rank : 97)	θ value	4.74913e-17 (rank : 62)
Query Neighborhood Hits	225	Target Neighborhood Hits	162	Shared Neighborhood Hits	95
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_MOUSE
NC score	0.432065 (rank : 98)	θ value	1.29331e-14 (rank : 76)
Query Neighborhood Hits	225	Target Neighborhood Hits	190	Shared Neighborhood Hits	95
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

UNC5D_HUMAN
NC score	0.431954 (rank : 99)	θ value	4.45536e-07 (rank : 96)
Query Neighborhood Hits	225	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

SEM5B_HUMAN
NC score	0.430858 (rank : 100)	θ value	1.13037e-18 (rank : 53)
Query Neighborhood Hits	225	Target Neighborhood Hits	178	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

UNC5D_MOUSE
NC score	0.428374 (rank : 101)	θ value	5.81887e-07 (rank : 98)
Query Neighborhood Hits	225	Target Neighborhood Hits	268	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

CO8A_MOUSE
NC score	0.426413 (rank : 102)	θ value	5.81887e-07 (rank : 97)
Query Neighborhood Hits	225	Target Neighborhood Hits	182	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ADA18_MOUSE
NC score	0.426235 (rank : 103)	θ value	0.0148317 (rank : 120)
Query Neighborhood Hits	225	Target Neighborhood Hits	227	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

CO6_HUMAN
NC score	0.424704 (rank : 104)	θ value	9.92553e-07 (rank : 101)
Query Neighborhood Hits	225	Target Neighborhood Hits	331	Shared Neighborhood Hits	103
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ADAM2_HUMAN
NC score	0.417188 (rank : 105)	θ value	3.41135e-07 (rank : 94)
Query Neighborhood Hits	225	Target Neighborhood Hits	175	Shared Neighborhood Hits	90
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

CO8B_MOUSE
NC score	0.408492 (rank : 106)	θ value	1.09739e-05 (rank : 106)
Query Neighborhood Hits	225	Target Neighborhood Hits	224	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADA18_HUMAN
NC score	0.403041 (rank : 107)	θ value	0.000602161 (rank : 115)
Query Neighborhood Hits	225	Target Neighborhood Hits	184	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

CILP2_HUMAN
NC score	0.403037 (rank : 108)	θ value	8.40245e-06 (rank : 104)
Query Neighborhood Hits	225	Target Neighborhood Hits	307	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

ADA30_HUMAN
NC score	0.395142 (rank : 109)	θ value	5.44631e-05 (rank : 109)
Query Neighborhood Hits	225	Target Neighborhood Hits	391	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA10_MOUSE
NC score	0.391890 (rank : 110)	θ value	0.00228821 (rank : 116)
Query Neighborhood Hits	225	Target Neighborhood Hits	194	Shared Neighborhood Hits	94
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA10_HUMAN
NC score	0.390370 (rank : 111)	θ value	0.0252991 (rank : 121)
Query Neighborhood Hits	225	Target Neighborhood Hits	189	Shared Neighborhood Hits	97
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA17_MOUSE
NC score	0.388669 (rank : 112)	θ value	0.00509761 (rank : 117)
Query Neighborhood Hits	225	Target Neighborhood Hits	201	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

UNC5A_HUMAN
NC score	0.380403 (rank : 113)	θ value	4.45536e-07 (rank : 95)
Query Neighborhood Hits	225	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ADA17_HUMAN
NC score	0.378180 (rank : 114)	θ value	0.0113563 (rank : 119)
Query Neighborhood Hits	225	Target Neighborhood Hits	223	Shared Neighborhood Hits	97
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

CO7_HUMAN
NC score	0.378049 (rank : 115)	θ value	1.87187e-05 (rank : 107)
Query Neighborhood Hits	225	Target Neighborhood Hits	278	Shared Neighborhood Hits	92
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8B_HUMAN
NC score	0.372254 (rank : 116)	θ value	1.09739e-05 (rank : 105)
Query Neighborhood Hits	225	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

HMCN1_HUMAN
NC score	0.303647 (rank : 117)	θ value	1.99067e-23 (rank : 43)
Query Neighborhood Hits	225	Target Neighborhood Hits	983	Shared Neighborhood Hits	151
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CILP1_HUMAN
NC score	0.296017 (rank : 118)	θ value	9.29e-05 (rank : 111)
Query Neighborhood Hits	225	Target Neighborhood Hits	266	Shared Neighborhood Hits	82
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
NC score	0.290275 (rank : 119)	θ value	0.0961366 (rank : 125)
Query Neighborhood Hits	225	Target Neighborhood Hits	282	Shared Neighborhood Hits	82
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

WISP2_HUMAN
NC score	0.171985 (rank : 120)	θ value	0.00665767 (rank : 118)
Query Neighborhood Hits	225	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
NC score	0.170341 (rank : 121)	θ value	0.0736092 (rank : 124)
Query Neighborhood Hits	225	Target Neighborhood Hits	129	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WISP1_MOUSE
NC score	0.147112 (rank : 122)	θ value	0.279714 (rank : 135)
Query Neighborhood Hits	225	Target Neighborhood Hits	123	Shared Neighborhood Hits	63
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP1_HUMAN
NC score	0.138348 (rank : 123)	θ value	1.38821 (rank : 154)
Query Neighborhood Hits	225	Target Neighborhood Hits	121	Shared Neighborhood Hits	67
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

CYR61_HUMAN
NC score	0.133324 (rank : 124)	θ value	0.21417 (rank : 131)
Query Neighborhood Hits	225	Target Neighborhood Hits	159	Shared Neighborhood Hits	78
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

NOV_MOUSE
NC score	0.124751 (rank : 125)	θ value	0.62314 (rank : 143)
Query Neighborhood Hits	225	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

WISP3_HUMAN
NC score	0.120476 (rank : 126)	θ value	0.813845 (rank : 148)
Query Neighborhood Hits	225	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

CYR61_MOUSE
NC score	0.118650 (rank : 127)	θ value	0.365318 (rank : 136)
Query Neighborhood Hits	225	Target Neighborhood Hits	156	Shared Neighborhood Hits	71
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

FRAS1_MOUSE
NC score	0.118026 (rank : 128)	θ value	0.000158464 (rank : 112)
Query Neighborhood Hits	225	Target Neighborhood Hits	747	Shared Neighborhood Hits	135
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NOV_HUMAN
NC score	0.112685 (rank : 129)	θ value	0.62314 (rank : 142)
Query Neighborhood Hits	225	Target Neighborhood Hits	128	Shared Neighborhood Hits	60
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

RSPO4_MOUSE
NC score	0.110527 (rank : 130)	θ value	0.365318 (rank : 138)
Query Neighborhood Hits	225	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RSPO1_HUMAN
NC score	0.109578 (rank : 131)	θ value	0.21417 (rank : 133)
Query Neighborhood Hits	225	Target Neighborhood Hits	101	Shared Neighborhood Hits	53
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

KR106_HUMAN
NC score	0.106702 (rank : 132)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	225	Target Neighborhood Hits	347	Shared Neighborhood Hits	90
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

FRAS1_HUMAN
NC score	0.102503 (rank : 133)	θ value	0.125558 (rank : 127)
Query Neighborhood Hits	225	Target Neighborhood Hits	759	Shared Neighborhood Hits	133
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CTGF_MOUSE
NC score	0.102326 (rank : 134)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	225	Target Neighborhood Hits	124	Shared Neighborhood Hits	57
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

KR104_HUMAN
NC score	0.102048 (rank : 135)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	225	Target Neighborhood Hits	313	Shared Neighborhood Hits	80
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

CTGF_HUMAN
NC score	0.098641 (rank : 136)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	225	Target Neighborhood Hits	128	Shared Neighborhood Hits	59
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

RSPO1_MOUSE
NC score	0.098396 (rank : 137)	θ value	0.813845 (rank : 146)
Query Neighborhood Hits	225	Target Neighborhood Hits	85	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

SPON2_HUMAN
NC score	0.094546 (rank : 138)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	225	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

RSPO4_HUMAN
NC score	0.090901 (rank : 139)	θ value	0.365318 (rank : 137)
Query Neighborhood Hits	225	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

KRA98_HUMAN
NC score	0.087558 (rank : 140)	θ value	1.06291 (rank : 149)
Query Neighborhood Hits	225	Target Neighborhood Hits	185	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

RSPO3_HUMAN
NC score	0.086635 (rank : 141)	θ value	0.813845 (rank : 147)
Query Neighborhood Hits	225	Target Neighborhood Hits	128	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

KR102_HUMAN
NC score	0.086543 (rank : 142)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	225	Target Neighborhood Hits	264	Shared Neighborhood Hits	71
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR107_HUMAN
NC score	0.086454 (rank : 143)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	225	Target Neighborhood Hits	330	Shared Neighborhood Hits	82
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA51_HUMAN
NC score	0.083915 (rank : 144)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	225	Target Neighborhood Hits	288	Shared Neighborhood Hits	80
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

TENX_HUMAN
NC score	0.083799 (rank : 145)	θ value	4.1701e-05 (rank : 108)
Query Neighborhood Hits	225	Target Neighborhood Hits	789	Shared Neighborhood Hits	112
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

KRA58_HUMAN
NC score	0.081974 (rank : 146)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	81
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

SPON2_MOUSE
NC score	0.081450 (rank : 147)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	225	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

KRA53_HUMAN
NC score	0.080380 (rank : 148)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	225	Target Neighborhood Hits	331	Shared Neighborhood Hits	86
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

ZAN_MOUSE
NC score	0.080184 (rank : 149)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	225	Target Neighborhood Hits	808	Shared Neighborhood Hits	122
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KRA93_HUMAN
NC score	0.080170 (rank : 150)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	225	Target Neighborhood Hits	203	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

RSPO3_MOUSE
NC score	0.079595 (rank : 151)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	225	Target Neighborhood Hits	120	Shared Neighborhood Hits	44
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

KRA92_HUMAN
NC score	0.078517 (rank : 152)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	225	Target Neighborhood Hits	198	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

CO9_MOUSE
NC score	0.076206 (rank : 153)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	225	Target Neighborhood Hits	153	Shared Neighborhood Hits	38
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

KRA57_HUMAN
NC score	0.074981 (rank : 154)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	225	Target Neighborhood Hits	269	Shared Neighborhood Hits	69
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA54_HUMAN
NC score	0.074282 (rank : 155)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	225	Target Neighborhood Hits	270	Shared Neighborhood Hits	69
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

RSPO2_HUMAN
NC score	0.073216 (rank : 156)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	225	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

KR101_HUMAN
NC score	0.071269 (rank : 157)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	225	Target Neighborhood Hits	261	Shared Neighborhood Hits	70
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

MEGF6_HUMAN
NC score	0.069773 (rank : 158)	θ value	0.125558 (rank : 128)
Query Neighborhood Hits	225	Target Neighborhood Hits	671	Shared Neighborhood Hits	129
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LRP2_HUMAN
NC score	0.068670 (rank : 159)	θ value	0.0431538 (rank : 123)
Query Neighborhood Hits	225	Target Neighborhood Hits	573	Shared Neighborhood Hits	102
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

CO9_HUMAN
NC score	0.068482 (rank : 160)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	225	Target Neighborhood Hits	147	Shared Neighborhood Hits	29
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

RSPO2_MOUSE
NC score	0.067932 (rank : 161)	θ value	1.06291 (rank : 150)
Query Neighborhood Hits	225	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

LRP1B_HUMAN
NC score	0.067920 (rank : 162)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	225	Target Neighborhood Hits	602	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

NFX1_HUMAN
NC score	0.067728 (rank : 163)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	225	Target Neighborhood Hits	405	Shared Neighborhood Hits	59
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

LRP1_HUMAN
NC score	0.066764 (rank : 164)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	225	Target Neighborhood Hits	617	Shared Neighborhood Hits	109
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

KRA52_HUMAN
NC score	0.065997 (rank : 165)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	225	Target Neighborhood Hits	236	Shared Neighborhood Hits	60
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

TENA_MOUSE
NC score	0.063791 (rank : 166)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	225	Target Neighborhood Hits	596	Shared Neighborhood Hits	93
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

LRP1B_MOUSE
NC score	0.063561 (rank : 167)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	225	Target Neighborhood Hits	606	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

PCSK5_MOUSE
NC score	0.063491 (rank : 168)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	225	Target Neighborhood Hits	613	Shared Neighborhood Hits	107
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CRIM1_HUMAN
NC score	0.063258 (rank : 169)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	225	Target Neighborhood Hits	362	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR109_HUMAN
NC score	0.062487 (rank : 170)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	225	Target Neighborhood Hits	226	Shared Neighborhood Hits	57
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

COMP_HUMAN
NC score	0.061288 (rank : 171)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	225	Target Neighborhood Hits	258	Shared Neighborhood Hits	43
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KR10B_HUMAN
NC score	0.060346 (rank : 172)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	225	Target Neighborhood Hits	269	Shared Neighborhood Hits	64
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

NOTC1_HUMAN
NC score	0.060258 (rank : 173)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	225	Target Neighborhood Hits	906	Shared Neighborhood Hits	114
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KRA59_HUMAN
NC score	0.059923 (rank : 174)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	225	Target Neighborhood Hits	310	Shared Neighborhood Hits	70
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

COMP_MOUSE
NC score	0.059899 (rank : 175)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	225	Target Neighborhood Hits	290	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NOTC3_MOUSE
NC score	0.059875 (rank : 176)	θ value	0.125558 (rank : 129)
Query Neighborhood Hits	225	Target Neighborhood Hits	975	Shared Neighborhood Hits	114
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SREC_HUMAN
NC score	0.059741 (rank : 177)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	225	Target Neighborhood Hits	645	Shared Neighborhood Hits	103
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

KR105_HUMAN
NC score	0.059194 (rank : 178)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	225	Target Neighborhood Hits	271	Shared Neighborhood Hits	61
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

NELL2_HUMAN
NC score	0.059127 (rank : 179)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	225	Target Neighborhood Hits	449	Shared Neighborhood Hits	87
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

KR10C_HUMAN
NC score	0.059070 (rank : 180)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	225	Target Neighborhood Hits	219	Shared Neighborhood Hits	58
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

TENA_HUMAN
NC score	0.058897 (rank : 181)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	225	Target Neighborhood Hits	631	Shared Neighborhood Hits	98
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TSP3_HUMAN
NC score	0.058859 (rank : 182)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	225	Target Neighborhood Hits	250	Shared Neighborhood Hits	39
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

JAG2_MOUSE
NC score	0.058328 (rank : 183)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	225	Target Neighborhood Hits	504	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LTBP2_HUMAN
NC score	0.058259 (rank : 184)	θ value	0.47712 (rank : 139)
Query Neighborhood Hits	225	Target Neighborhood Hits	552	Shared Neighborhood Hits	93
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NELL2_MOUSE
NC score	0.057829 (rank : 185)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	225	Target Neighborhood Hits	436	Shared Neighborhood Hits	86
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

RELN_MOUSE
NC score	0.057733 (rank : 186)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	225	Target Neighborhood Hits	235	Shared Neighborhood Hits	53
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

JAG2_HUMAN
NC score	0.057700 (rank : 187)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	225	Target Neighborhood Hits	491	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

SREC2_MOUSE
NC score	0.057686 (rank : 188)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	225	Target Neighborhood Hits	605	Shared Neighborhood Hits	95
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

NOTC3_HUMAN
NC score	0.057686 (rank : 189)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	225	Target Neighborhood Hits	1062	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBN1_HUMAN
NC score	0.057624 (rank : 190)	θ value	0.0961366 (rank : 126)
Query Neighborhood Hits	225	Target Neighborhood Hits	557	Shared Neighborhood Hits	102
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

TSP3_MOUSE
NC score	0.057382 (rank : 191)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	225	Target Neighborhood Hits	247	Shared Neighborhood Hits	36
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

NOTC2_HUMAN
NC score	0.057268 (rank : 192)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	225	Target Neighborhood Hits	1113	Shared Neighborhood Hits	113
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FBN2_MOUSE
NC score	0.057260 (rank : 193)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	225	Target Neighborhood Hits	549	Shared Neighborhood Hits	108
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG1_HUMAN
NC score	0.057253 (rank : 194)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	225	Target Neighborhood Hits	514	Shared Neighborhood Hits	99
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

NOTC2_MOUSE
NC score	0.057172 (rank : 195)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	225	Target Neighborhood Hits	1069	Shared Neighborhood Hits	106
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_MOUSE
NC score	0.056634 (rank : 196)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	225	Target Neighborhood Hits	916	Shared Neighborhood Hits	104
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

TSP4_HUMAN
NC score	0.056227 (rank : 197)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	225	Target Neighborhood Hits	277	Shared Neighborhood Hits	37
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

JAG1_MOUSE
NC score	0.056182 (rank : 198)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	225	Target Neighborhood Hits	518	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FBN2_HUMAN
NC score	0.056179 (rank : 199)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	225	Target Neighborhood Hits	560	Shared Neighborhood Hits	107
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

DLL1_MOUSE
NC score	0.055693 (rank : 200)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	225	Target Neighborhood Hits	456	Shared Neighborhood Hits	93
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

KR412_HUMAN
NC score	0.055487 (rank : 201)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	225	Target Neighborhood Hits	178	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

RELN_HUMAN
NC score	0.055474 (rank : 202)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	225	Target Neighborhood Hits	233	Shared Neighborhood Hits	51
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

TSP4_MOUSE
NC score	0.055286 (rank : 203)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	225	Target Neighborhood Hits	276	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

LTBP3_MOUSE
NC score	0.054981 (rank : 204)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	225	Target Neighborhood Hits	475	Shared Neighborhood Hits	87
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBN1_MOUSE
NC score	0.054880 (rank : 205)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	225	Target Neighborhood Hits	563	Shared Neighborhood Hits	102
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

KRA99_HUMAN
NC score	0.054424 (rank : 206)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	225	Target Neighborhood Hits	173	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

SREC2_HUMAN
NC score	0.054379 (rank : 207)	θ value	1.38821 (rank : 153)
Query Neighborhood Hits	225	Target Neighborhood Hits	645	Shared Neighborhood Hits	89
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

KR414_HUMAN
NC score	0.054344 (rank : 208)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	225	Target Neighborhood Hits	199	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

NAGPA_MOUSE
NC score	0.054276 (rank : 209)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	225	Target Neighborhood Hits	308	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LDLR_HUMAN
NC score	0.054255 (rank : 210)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	225	Target Neighborhood Hits	375	Shared Neighborhood Hits	82
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MT1B_HUMAN
NC score	0.054065 (rank : 211)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	225	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

KR510_HUMAN
NC score	0.053716 (rank : 212)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	225	Target Neighborhood Hits	217	Shared Neighborhood Hits	49
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA94_HUMAN
NC score	0.053360 (rank : 213)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	225	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

LTB1L_MOUSE
NC score	0.053107 (rank : 214)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	225	Target Neighborhood Hits	514	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_MOUSE
NC score	0.052946 (rank : 215)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	225	Target Neighborhood Hits	617	Shared Neighborhood Hits	92
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN3_HUMAN
NC score	0.052524 (rank : 216)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	225	Target Neighborhood Hits	543	Shared Neighborhood Hits	100
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

C1QR1_HUMAN
NC score	0.052345 (rank : 217)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	225	Target Neighborhood Hits	493	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CD97_MOUSE
NC score	0.052302 (rank : 218)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	225	Target Neighborhood Hits	295	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

LTB1S_MOUSE
NC score	0.052291 (rank : 219)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	225	Target Neighborhood Hits	479	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.052260 (rank : 220)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	225	Target Neighborhood Hits	553	Shared Neighborhood Hits	89
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NELL1_HUMAN
NC score	0.052200 (rank : 221)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	225	Target Neighborhood Hits	451	Shared Neighborhood Hits	81
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

DLL1_HUMAN
NC score	0.051826 (rank : 222)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	225	Target Neighborhood Hits	455	Shared Neighborhood Hits	91
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LTB1S_HUMAN
NC score	0.051806 (rank : 223)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	225	Target Neighborhood Hits	502	Shared Neighborhood Hits	86
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ELTD1_HUMAN
NC score	0.051469 (rank : 224)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	225	Target Neighborhood Hits	269	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

EMR1_MOUSE
NC score	0.051160 (rank : 225)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	225	Target Neighborhood Hits	349	Shared Neighborhood Hits	51
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

STAB2_MOUSE
NC score	0.051096 (rank : 226)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	225	Target Neighborhood Hits	528	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

EMR1_HUMAN
NC score	0.050915 (rank : 227)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	225	Target Neighborhood Hits	382	Shared Neighborhood Hits	54
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

LTBP3_HUMAN
NC score	0.050504 (rank : 228)	θ value	0.47712 (rank : 140)
Query Neighborhood Hits	225	Target Neighborhood Hits	502	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ELTD1_MOUSE
NC score	0.050477 (rank : 229)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	225	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

LRP4_MOUSE
NC score	0.050307 (rank : 230)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	225	Target Neighborhood Hits	351	Shared Neighborhood Hits	76
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

WIF1_MOUSE
NC score	0.050151 (rank : 231)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	225	Target Neighborhood Hits	393	Shared Neighborhood Hits	78
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NOTC4_MOUSE
NC score	0.049211 (rank : 232)	θ value	0.163984 (rank : 130)
Query Neighborhood Hits	225	Target Neighborhood Hits	872	Shared Neighborhood Hits	107
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

LRP8_MOUSE
NC score	0.048574 (rank : 233)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	225	Target Neighborhood Hits	385	Shared Neighborhood Hits	76
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SORL_HUMAN
NC score	0.048222 (rank : 234)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	225	Target Neighborhood Hits	440	Shared Neighborhood Hits	74
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

VLDLR_MOUSE
NC score	0.047024 (rank : 235)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	225	Target Neighborhood Hits	360	Shared Neighborhood Hits	75
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_HUMAN
NC score	0.046274 (rank : 236)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	225	Target Neighborhood Hits	383	Shared Neighborhood Hits	75
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

MUC5B_HUMAN
NC score	0.046127 (rank : 237)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	225	Target Neighborhood Hits	1020	Shared Neighborhood Hits	78
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SORL_MOUSE
NC score	0.042847 (rank : 238)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	225	Target Neighborhood Hits	439	Shared Neighborhood Hits	70
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

FBLN2_MOUSE
NC score	0.042172 (rank : 239)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	225	Target Neighborhood Hits	505	Shared Neighborhood Hits	62
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

MEGF8_HUMAN
NC score	0.037380 (rank : 240)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	225	Target Neighborhood Hits	528	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
NC score	0.037280 (rank : 241)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	225	Target Neighborhood Hits	520	Shared Neighborhood Hits	69
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MUC2_HUMAN
NC score	0.034607 (rank : 242)	θ value	1.38821 (rank : 152)
Query Neighborhood Hits	225	Target Neighborhood Hits	906	Shared Neighborhood Hits	58
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

C1QR1_MOUSE
NC score	0.034119 (rank : 243)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	225	Target Neighborhood Hits	342	Shared Neighborhood Hits	46
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

EGF_HUMAN
NC score	0.031598 (rank : 244)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	225	Target Neighborhood Hits	343	Shared Neighborhood Hits	49
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

ITB6_HUMAN
NC score	0.030714 (rank : 245)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	225	Target Neighborhood Hits	318	Shared Neighborhood Hits	70
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

CELR2_MOUSE
NC score	0.026458 (rank : 246)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	225	Target Neighborhood Hits	584	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

SLIT1_MOUSE
NC score	0.024817 (rank : 247)	θ value	0.0330416 (rank : 122)
Query Neighborhood Hits	225	Target Neighborhood Hits	715	Shared Neighborhood Hits	73
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ZNFX1_MOUSE
NC score	0.022130 (rank : 248)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	225	Target Neighborhood Hits	407	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ST14_HUMAN
NC score	0.020529 (rank : 249)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	225	Target Neighborhood Hits	409	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

WFDC8_HUMAN
NC score	0.016611 (rank : 250)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	225	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

CJ086_HUMAN
NC score	0.016352 (rank : 251)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	225	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXX6, Q5SQQ5, Q6P673, Q8WY66, Q9BS90	Gene names	C10orf86
Domain Architecture	No domain graphic available
Description	Protein C10orf86.

FSTL1_HUMAN
NC score	0.014628 (rank : 252)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	225	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
NC score	0.014105 (rank : 253)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	225	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

ICAM5_MOUSE
NC score	0.013256 (rank : 254)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	225	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

IZUM1_HUMAN
NC score	0.011288 (rank : 255)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	225	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYV9, Q6Q8P6, Q6Q8P7	Gene names	IZUMO1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

I17RA_HUMAN
NC score	0.011230 (rank : 256)	θ value	0.813845 (rank : 144)
Query Neighborhood Hits	225	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q96F46, O43844	Gene names	IL17RA, IL17R
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

LASP1_HUMAN
NC score	0.009323 (rank : 257)	θ value	0.21417 (rank : 132)
Query Neighborhood Hits	225	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

ARI2_HUMAN
NC score	0.009103 (rank : 258)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	225	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

LASP1_MOUSE
NC score	0.008953 (rank : 259)	θ value	0.279714 (rank : 134)
Query Neighborhood Hits	225	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

ARI2_MOUSE
NC score	0.008181 (rank : 260)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	225	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

CFAH_HUMAN
NC score	0.007961 (rank : 261)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	225	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

PHF12_MOUSE
NC score	0.007869 (rank : 262)	θ value	0.813845 (rank : 145)
Query Neighborhood Hits	225	Target Neighborhood Hits	172	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PIPNB_HUMAN
NC score	0.007009 (rank : 263)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	225	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P48739, Q8N5W1	Gene names	PITPNB
Domain Architecture
Description	Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta).

TF3C4_MOUSE
NC score	0.006945 (rank : 264)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	225	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMQ2, Q8BKZ4	Gene names	Gtf3c4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

PIPNB_MOUSE
NC score	0.006565 (rank : 265)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	225	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P53811	Gene names	Pitpnb
Domain Architecture
Description	Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta).

TF3C4_HUMAN
NC score	0.006298 (rank : 266)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	225	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKN8	Gene names	GTF3C4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

HNF1B_HUMAN
NC score	0.005987 (rank : 267)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	225	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	P35680	Gene names	TCF2, HNF1B
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2).

HNF1B_MOUSE
NC score	0.005457 (rank : 268)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	225	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

MLL2_HUMAN
NC score	0.005408 (rank : 269)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	225	Target Neighborhood Hits	1788	Shared Neighborhood Hits	33
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TRI42_MOUSE
NC score	0.004704 (rank : 270)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	225	Target Neighborhood Hits	316	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

NU133_HUMAN
NC score	0.004654 (rank : 271)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	225	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

UBP54_HUMAN
NC score	0.004593 (rank : 272)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	225	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

TRI42_HUMAN
NC score	0.003755 (rank : 273)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	225	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

LAP2A_HUMAN
NC score	0.003058 (rank : 274)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	225	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

APOA_HUMAN
NC score	0.002993 (rank : 275)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	225	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

DOK1_HUMAN
NC score	0.002826 (rank : 276)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	225	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

SASH1_HUMAN
NC score	0.002713 (rank : 277)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	225	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

CAH9_HUMAN
NC score	0.002617 (rank : 278)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	225	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q16790	Gene names	CA9, G250, MN
Domain Architecture
Description	Carbonic anhydrase 9 precursor (EC 4.2.1.1) (Carbonic anhydrase IX) (Carbonate dehydratase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC- associated antigen G250) (pMW1).

RASF5_HUMAN
NC score	0.002558 (rank : 279)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	225	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

AT1B2_HUMAN
NC score	0.001980 (rank : 280)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	225	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P14415, O60444	Gene names	ATP1B2
Domain Architecture
Description	Sodium/potassium-transporting ATPase subunit beta-2 (Sodium/potassium- dependent ATPase beta-2 subunit).

ITA8_HUMAN
NC score	0.001706 (rank : 281)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	225	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P53708, Q5VX94	Gene names	ITGA8
Domain Architecture
Description	Integrin alpha-8 precursor [Contains: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain].

ACINU_MOUSE
NC score	0.001145 (rank : 282)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	225	Target Neighborhood Hits	712	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TCGAP_HUMAN
NC score	0.000588 (rank : 283)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	225	Target Neighborhood Hits	872	Shared Neighborhood Hits	12
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TF7L2_MOUSE
NC score	0.000349 (rank : 284)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	225	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

MRP7_MOUSE
NC score	-0.000435 (rank : 285)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	225	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

NR1H3_HUMAN
NC score	-0.002058 (rank : 286)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	225	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

IRAK3_HUMAN
NC score	-0.005213 (rank : 287)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	225	Target Neighborhood Hits	644	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

ZN746_HUMAN
NC score	-0.005991 (rank : 288)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	225	Target Neighborhood Hits	745	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

ZN746_MOUSE
NC score	-0.006489 (rank : 289)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	225	Target Neighborhood Hits	748	Shared Neighborhood Hits	10
SwissProt Accessions	Q3U133	Gene names	Znf746, Zfp746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

ZN567_HUMAN
NC score	-0.006580 (rank : 290)	θ value	1.06291 (rank : 151)
Query Neighborhood Hits	225	Target Neighborhood Hits	769	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N184, Q6N044	Gene names	ZNF567
Domain Architecture	No domain graphic available
Description	Zinc finger protein 567.

ZFP11_MOUSE
NC score	-0.006742 (rank : 291)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	225	Target Neighborhood Hits	763	Shared Neighborhood Hits	12
SwissProt Accessions	P10751, Q505E4, Q6PDR5, Q8BSI2, Q8C3R5	Gene names	Zfp11, Krox-6.1a
Domain Architecture	No domain graphic available
Description	Zinc finger protein 11 (Zfp-11) (Krox-6.1A protein).

ZN224_HUMAN
NC score	-0.006935 (rank : 292)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	225	Target Neighborhood Hits	808	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZL3, Q86V10, Q8IZC8, Q9UID9, Q9Y2P6	Gene names	ZNF224, BMZF2, ZNF255
Domain Architecture
Description	Zinc finger protein 224 (Zinc finger protein 255) (Bone marrow zinc finger 2) (BMZF-2).

ZN432_HUMAN
NC score	-0.007012 (rank : 293)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	225	Target Neighborhood Hits	764	Shared Neighborhood Hits	10
SwissProt Accessions	O94892	Gene names	ZNF432, KIAA0798
Domain Architecture
Description	Zinc finger protein 432.

ZNF81_HUMAN
NC score	-0.007048 (rank : 294)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	225	Target Neighborhood Hits	786	Shared Neighborhood Hits	13
SwissProt Accessions	P51508, Q6RX22, Q96QH6	Gene names	ZNF81
Domain Architecture	No domain graphic available
Description	Zinc finger protein 81 (HFZ20).

ZN672_HUMAN
NC score	-0.007284 (rank : 295)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	225	Target Neighborhood Hits	744	Shared Neighborhood Hits	10
SwissProt Accessions	Q499Z4, Q96H65, Q96IM3, Q9H6G5	Gene names	ZNF672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.