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Network neighborhood for query Sequence : I17RA_HUMAN

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I17RA_HUMAN
SwissProt Accessions	Q96F46, O43844	Gene names	IL17RA, IL17R
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

I17RA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q96F46, O43844	Gene names	IL17RA, IL17R
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

I17RA_MOUSE
θ value	0 (rank : 2)	NC score	0.987260 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q60943	Gene names	IL17ra, Il17r
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

I17RB_HUMAN
θ value	3.61944e-33 (rank : 3)	NC score	0.728568 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRM6, Q9BPZ0, Q9NRL4, Q9NRM5	Gene names	IL17RB, EVI27, IL17BR
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor B precursor (IL-17 receptor B) (IL-17RB) (Interleukin-17B receptor) (IL-17B receptor) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Cytokine receptor CRL4).

I17RB_MOUSE
θ value	4.89182e-30 (rank : 4)	NC score	0.705037 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIP3, Q9JIP2	Gene names	Il17rb, Evi27, Il17br
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor B precursor (IL-17 receptor B) (IL-17RB) (Interleukin-17B receptor) (IL-17B receptor) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (IL-17ER).

I17RD_HUMAN
θ value	7.0802e-21 (rank : 5)	NC score	0.569717 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFM7, Q58EZ7, Q6RVF4, Q6UWI5, Q8N113, Q8NFS0, Q9UFA0	Gene names	IL17RD, IL17RLM, SEF
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor D precursor (IL-17 receptor D) (IL-17RD) (Interleukin-17D receptor) (IL-17D receptor) (IL17Rhom) (Interleukin- 17 receptor-like protein) (Sef homolog) (hSef).

I17RD_MOUSE
θ value	6.20254e-17 (rank : 6)	NC score	0.541600 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q8JZL1, Q8K447, Q8R5J8	Gene names	Il17rd, Il17rlm, Sef
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor D precursor (IL-17 receptor D) (IL-17RD) (Interleukin-17D receptor) (IL-17D receptor) (Interleukin-17 receptor- like protein) (Sef homolog) (mSef).

I17RC_HUMAN
θ value	1.17247e-07 (rank : 7)	NC score	0.296538 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NAC3, Q6UVY3, Q6UWD4, Q8NFS1, Q9BR97	Gene names	IL17RC
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor C precursor (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor-like protein) (IL-17RL) (Interleukin-17 receptor homolog) (IL17Rhom).

I17RC_MOUSE
θ value	4.92598e-06 (rank : 8)	NC score	0.286558 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4C2, Q99J43	Gene names	Il17rc
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor C precursor (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor-like protein) (IL-17RL).

HXB9_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.022534 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	P20615	Gene names	Hoxb9, Hox-2.5, Hoxb-9
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2.5).

ZN447_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.015065 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	899	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

CITE1_MOUSE
θ value	0.21417 (rank : 11)	NC score	0.062812 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P97769	Gene names	Cited1, Msg1
Domain Architecture
Description	Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1).

SIAH2_HUMAN
θ value	0.21417 (rank : 12)	NC score	0.037065 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

ANR38_MOUSE
θ value	0.62314 (rank : 13)	NC score	0.020616 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	512	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ATS20_MOUSE
θ value	0.813845 (rank : 14)	NC score	0.011230 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

NEUR4_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.029840 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWR8, Q96D64	Gene names	NEU4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4).

TIF1B_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.018823 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	312	Shared Neighborhood Hits	2
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

HXB9_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.016086 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	P17482, Q9H1I1	Gene names	HOXB9, HOX2E
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5).

UB7I1_MOUSE
θ value	2.36792 (rank : 18)	NC score	0.029310 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

PSB10_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.017546 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	O35955, O08687, Q99KC5	Gene names	Psmb10, Lmp10, Mecl1
Domain Architecture
Description	Proteasome subunit beta type 10 precursor (EC 3.4.25.1) (Proteasome MECl-1) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1).

CARD6_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.025252 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	145	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

CEBPD_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.018838 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

MILK2_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.011273 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	457	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

ETV3_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.010773 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

PURA1_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.014571 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P28650, Q8CHQ1	Gene names	Adssl1, Adss1
Domain Architecture
Description	Adenylosuccinate synthetase isozyme 1 (EC 6.3.4.4) (Adenylosuccinate synthetase, muscle isozyme) (IMP--aspartate ligase 1) (AdSS 1) (AMPSase 1).

TNFC_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.021290 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P41155	Gene names	Ltb, Tnfc, Tnfsf3
Domain Architecture
Description	Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3).

B4GT1_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.008604 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CSTFT_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.010285 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

CSTFT_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.009911 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

GP152_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.005739 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	636	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

HDAC6_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.008565 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

RINI_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.008747 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

HD_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.010984 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

HEMGN_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.014787 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

LGR5_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.002205 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	484	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1P4	Gene names	Lgr5, Fex, Gpr49
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (G-protein coupled receptor 49) (Orphan G-protein coupled receptor FEX).

TNR27_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.011134 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

UB7I1_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.022223 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

Hits sorted by NC score

I17RA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q96F46, O43844	Gene names	IL17RA, IL17R
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

I17RA_MOUSE
NC score	0.987260 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q60943	Gene names	IL17ra, Il17r
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

I17RB_HUMAN
NC score	0.728568 (rank : 3)	θ value	3.61944e-33 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRM6, Q9BPZ0, Q9NRL4, Q9NRM5	Gene names	IL17RB, EVI27, IL17BR
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor B precursor (IL-17 receptor B) (IL-17RB) (Interleukin-17B receptor) (IL-17B receptor) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Cytokine receptor CRL4).

I17RB_MOUSE
NC score	0.705037 (rank : 4)	θ value	4.89182e-30 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIP3, Q9JIP2	Gene names	Il17rb, Evi27, Il17br
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor B precursor (IL-17 receptor B) (IL-17RB) (Interleukin-17B receptor) (IL-17B receptor) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (IL-17ER).

I17RD_HUMAN
NC score	0.569717 (rank : 5)	θ value	7.0802e-21 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFM7, Q58EZ7, Q6RVF4, Q6UWI5, Q8N113, Q8NFS0, Q9UFA0	Gene names	IL17RD, IL17RLM, SEF
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor D precursor (IL-17 receptor D) (IL-17RD) (Interleukin-17D receptor) (IL-17D receptor) (IL17Rhom) (Interleukin- 17 receptor-like protein) (Sef homolog) (hSef).

I17RD_MOUSE
NC score	0.541600 (rank : 6)	θ value	6.20254e-17 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q8JZL1, Q8K447, Q8R5J8	Gene names	Il17rd, Il17rlm, Sef
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor D precursor (IL-17 receptor D) (IL-17RD) (Interleukin-17D receptor) (IL-17D receptor) (Interleukin-17 receptor- like protein) (Sef homolog) (mSef).

I17RC_HUMAN
NC score	0.296538 (rank : 7)	θ value	1.17247e-07 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NAC3, Q6UVY3, Q6UWD4, Q8NFS1, Q9BR97	Gene names	IL17RC
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor C precursor (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor-like protein) (IL-17RL) (Interleukin-17 receptor homolog) (IL17Rhom).

I17RC_MOUSE
NC score	0.286558 (rank : 8)	θ value	4.92598e-06 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4C2, Q99J43	Gene names	Il17rc
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor C precursor (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor-like protein) (IL-17RL).

CITE1_MOUSE
NC score	0.062812 (rank : 9)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P97769	Gene names	Cited1, Msg1
Domain Architecture
Description	Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1).

SIAH2_HUMAN
NC score	0.037065 (rank : 10)	θ value	0.21417 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

NEUR4_HUMAN
NC score	0.029840 (rank : 11)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWR8, Q96D64	Gene names	NEU4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4).

UB7I1_MOUSE
NC score	0.029310 (rank : 12)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

CARD6_HUMAN
NC score	0.025252 (rank : 13)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	145	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

HXB9_MOUSE
NC score	0.022534 (rank : 14)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	P20615	Gene names	Hoxb9, Hox-2.5, Hoxb-9
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2.5).

UB7I1_HUMAN
NC score	0.022223 (rank : 15)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

TNFC_MOUSE
NC score	0.021290 (rank : 16)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P41155	Gene names	Ltb, Tnfc, Tnfsf3
Domain Architecture
Description	Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3).

ANR38_MOUSE
NC score	0.020616 (rank : 17)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	512	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CEBPD_MOUSE
NC score	0.018838 (rank : 18)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

TIF1B_HUMAN
NC score	0.018823 (rank : 19)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	312	Shared Neighborhood Hits	2
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

PSB10_MOUSE
NC score	0.017546 (rank : 20)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	O35955, O08687, Q99KC5	Gene names	Psmb10, Lmp10, Mecl1
Domain Architecture
Description	Proteasome subunit beta type 10 precursor (EC 3.4.25.1) (Proteasome MECl-1) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1).

HXB9_HUMAN
NC score	0.016086 (rank : 21)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	P17482, Q9H1I1	Gene names	HOXB9, HOX2E
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5).

ZN447_HUMAN
NC score	0.015065 (rank : 22)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	899	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

HEMGN_MOUSE
NC score	0.014787 (rank : 23)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

PURA1_MOUSE
NC score	0.014571 (rank : 24)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P28650, Q8CHQ1	Gene names	Adssl1, Adss1
Domain Architecture
Description	Adenylosuccinate synthetase isozyme 1 (EC 6.3.4.4) (Adenylosuccinate synthetase, muscle isozyme) (IMP--aspartate ligase 1) (AdSS 1) (AMPSase 1).

MILK2_HUMAN
NC score	0.011273 (rank : 25)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	457	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

ATS20_MOUSE
NC score	0.011230 (rank : 26)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

TNR27_MOUSE
NC score	0.011134 (rank : 27)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

HD_HUMAN
NC score	0.010984 (rank : 28)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

ETV3_HUMAN
NC score	0.010773 (rank : 29)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

CSTFT_HUMAN
NC score	0.010285 (rank : 30)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

CSTFT_MOUSE
NC score	0.009911 (rank : 31)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

RINI_HUMAN
NC score	0.008747 (rank : 32)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

B4GT1_MOUSE
NC score	0.008604 (rank : 33)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

HDAC6_HUMAN
NC score	0.008565 (rank : 34)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

GP152_HUMAN
NC score	0.005739 (rank : 35)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	636	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

LGR5_MOUSE
NC score	0.002205 (rank : 36)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	484	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1P4	Gene names	Lgr5, Fex, Gpr49
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (G-protein coupled receptor 49) (Orphan G-protein coupled receptor FEX).