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Network neighborhood for query Sequence : ADA33_HUMAN

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ADA33_HUMAN
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ADA19_HUMAN
θ value	0 (rank : 1)	NC score	0.982065 (rank : 5)
Query Neighborhood Hits	264	Target Neighborhood Hits	381	Shared Neighborhood Hits	172
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA33_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	264	Target Neighborhood Hits	264	Shared Neighborhood Hits	264
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	0 (rank : 3)	NC score	0.991185 (rank : 2)
Query Neighborhood Hits	264	Target Neighborhood Hits	231	Shared Neighborhood Hits	186
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA19_MOUSE
θ value	1.0077e-184 (rank : 4)	NC score	0.983579 (rank : 3)
Query Neighborhood Hits	264	Target Neighborhood Hits	315	Shared Neighborhood Hits	180
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA12_MOUSE
θ value	6.34118e-171 (rank : 5)	NC score	0.970112 (rank : 14)
Query Neighborhood Hits	264	Target Neighborhood Hits	474	Shared Neighborhood Hits	155
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_HUMAN
θ value	1.56188e-169 (rank : 6)	NC score	0.982856 (rank : 4)
Query Neighborhood Hits	264	Target Neighborhood Hits	224	Shared Neighborhood Hits	150
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	1.98959e-140 (rank : 7)	NC score	0.978033 (rank : 6)
Query Neighborhood Hits	264	Target Neighborhood Hits	288	Shared Neighborhood Hits	169
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADAM8_HUMAN
θ value	2.13557e-126 (rank : 8)	NC score	0.973567 (rank : 9)
Query Neighborhood Hits	264	Target Neighborhood Hits	327	Shared Neighborhood Hits	186
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA15_MOUSE
θ value	1.38424e-125 (rank : 9)	NC score	0.972567 (rank : 13)
Query Neighborhood Hits	264	Target Neighborhood Hits	324	Shared Neighborhood Hits	183
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADAM8_MOUSE
θ value	1.13501e-119 (rank : 10)	NC score	0.973072 (rank : 10)
Query Neighborhood Hits	264	Target Neighborhood Hits	326	Shared Neighborhood Hits	187
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADA28_MOUSE
θ value	1.06234e-117 (rank : 11)	NC score	0.974604 (rank : 7)
Query Neighborhood Hits	264	Target Neighborhood Hits	241	Shared Neighborhood Hits	155
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADAM9_HUMAN
θ value	1.69605e-115 (rank : 12)	NC score	0.974426 (rank : 8)
Query Neighborhood Hits	264	Target Neighborhood Hits	243	Shared Neighborhood Hits	166
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	4.1775e-114 (rank : 13)	NC score	0.972598 (rank : 12)
Query Neighborhood Hits	264	Target Neighborhood Hits	325	Shared Neighborhood Hits	173
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA28_HUMAN
θ value	1.02895e-112 (rank : 14)	NC score	0.972722 (rank : 11)
Query Neighborhood Hits	264	Target Neighborhood Hits	244	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA11_MOUSE
θ value	1.26366e-94 (rank : 15)	NC score	0.955881 (rank : 26)
Query Neighborhood Hits	264	Target Neighborhood Hits	263	Shared Neighborhood Hits	176
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADAM7_HUMAN
θ value	1.54472e-92 (rank : 16)	NC score	0.969884 (rank : 15)
Query Neighborhood Hits	264	Target Neighborhood Hits	221	Shared Neighborhood Hits	163
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADA11_HUMAN
θ value	5.86991e-92 (rank : 17)	NC score	0.951751 (rank : 30)
Query Neighborhood Hits	264	Target Neighborhood Hits	259	Shared Neighborhood Hits	175
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA21_HUMAN
θ value	9.37149e-90 (rank : 18)	NC score	0.956067 (rank : 25)
Query Neighborhood Hits	264	Target Neighborhood Hits	181	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA22_HUMAN
θ value	1.59853e-89 (rank : 19)	NC score	0.958843 (rank : 20)
Query Neighborhood Hits	264	Target Neighborhood Hits	211	Shared Neighborhood Hits	140
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADM1A_MOUSE
θ value	1.35324e-88 (rank : 20)	NC score	0.963000 (rank : 17)
Query Neighborhood Hits	264	Target Neighborhood Hits	230	Shared Neighborhood Hits	163
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA20_HUMAN
θ value	2.30828e-88 (rank : 21)	NC score	0.947974 (rank : 34)
Query Neighborhood Hits	264	Target Neighborhood Hits	143	Shared Neighborhood Hits	115
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA23_MOUSE
θ value	2.5521e-87 (rank : 22)	NC score	0.958477 (rank : 21)
Query Neighborhood Hits	264	Target Neighborhood Hits	245	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA21_MOUSE
θ value	1.2666e-86 (rank : 23)	NC score	0.960515 (rank : 18)
Query Neighborhood Hits	264	Target Neighborhood Hits	172	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA23_HUMAN
θ value	1.2666e-86 (rank : 24)	NC score	0.958309 (rank : 22)
Query Neighborhood Hits	264	Target Neighborhood Hits	235	Shared Neighborhood Hits	162
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA25_MOUSE
θ value	3.68522e-86 (rank : 25)	NC score	0.957959 (rank : 23)
Query Neighborhood Hits	264	Target Neighborhood Hits	213	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA30_HUMAN
θ value	1.07224e-85 (rank : 26)	NC score	0.934939 (rank : 40)
Query Neighborhood Hits	264	Target Neighborhood Hits	391	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA22_MOUSE
θ value	2.38869e-85 (rank : 27)	NC score	0.955028 (rank : 27)
Query Neighborhood Hits	264	Target Neighborhood Hits	225	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADAM7_MOUSE
θ value	2.91998e-83 (rank : 28)	NC score	0.966154 (rank : 16)
Query Neighborhood Hits	264	Target Neighborhood Hits	200	Shared Neighborhood Hits	142
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

AD26A_MOUSE
θ value	9.39325e-82 (rank : 29)	NC score	0.954579 (rank : 28)
Query Neighborhood Hits	264	Target Neighborhood Hits	165	Shared Neighborhood Hits	135
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADM1B_MOUSE
θ value	1.2268e-81 (rank : 30)	NC score	0.959449 (rank : 19)
Query Neighborhood Hits	264	Target Neighborhood Hits	236	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA18_HUMAN
θ value	3.0217e-80 (rank : 31)	NC score	0.935280 (rank : 39)
Query Neighborhood Hits	264	Target Neighborhood Hits	184	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA24_MOUSE
θ value	3.0217e-80 (rank : 32)	NC score	0.956372 (rank : 24)
Query Neighborhood Hits	264	Target Neighborhood Hits	230	Shared Neighborhood Hits	159
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA29_HUMAN
θ value	1.26953e-78 (rank : 33)	NC score	0.950489 (rank : 31)
Query Neighborhood Hits	264	Target Neighborhood Hits	247	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA32_HUMAN
θ value	1.71583e-75 (rank : 34)	NC score	0.948874 (rank : 32)
Query Neighborhood Hits	264	Target Neighborhood Hits	216	Shared Neighborhood Hits	156
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA18_MOUSE
θ value	2.92676e-75 (rank : 35)	NC score	0.942837 (rank : 37)
Query Neighborhood Hits	264	Target Neighborhood Hits	227	Shared Neighborhood Hits	158
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADAM2_HUMAN
θ value	1.45253e-74 (rank : 36)	NC score	0.939436 (rank : 38)
Query Neighborhood Hits	264	Target Neighborhood Hits	175	Shared Neighborhood Hits	132
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
θ value	4.22625e-74 (rank : 37)	NC score	0.948095 (rank : 33)
Query Neighborhood Hits	264	Target Neighborhood Hits	209	Shared Neighborhood Hits	149
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADA32_MOUSE
θ value	7.20884e-74 (rank : 38)	NC score	0.947180 (rank : 35)
Query Neighborhood Hits	264	Target Neighborhood Hits	219	Shared Neighborhood Hits	155
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADEC1_HUMAN
θ value	3.47335e-60 (rank : 39)	NC score	0.952386 (rank : 29)
Query Neighborhood Hits	264	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	4.25575e-50 (rank : 40)	NC score	0.943650 (rank : 36)
Query Neighborhood Hits	264	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA10_MOUSE
θ value	8.08199e-25 (rank : 41)	NC score	0.822389 (rank : 41)
Query Neighborhood Hits	264	Target Neighborhood Hits	194	Shared Neighborhood Hits	132
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA17_HUMAN
θ value	1.80048e-24 (rank : 42)	NC score	0.801993 (rank : 44)
Query Neighborhood Hits	264	Target Neighborhood Hits	223	Shared Neighborhood Hits	130
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA10_HUMAN
θ value	3.07116e-24 (rank : 43)	NC score	0.819372 (rank : 42)
Query Neighborhood Hits	264	Target Neighborhood Hits	189	Shared Neighborhood Hits	127
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ATS16_HUMAN
θ value	6.40375e-22 (rank : 44)	NC score	0.581059 (rank : 49)
Query Neighborhood Hits	264	Target Neighborhood Hits	208	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ADA17_MOUSE
θ value	8.36355e-22 (rank : 45)	NC score	0.803318 (rank : 43)
Query Neighborhood Hits	264	Target Neighborhood Hits	201	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ATS14_HUMAN
θ value	8.36355e-22 (rank : 46)	NC score	0.556054 (rank : 62)
Query Neighborhood Hits	264	Target Neighborhood Hits	382	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS16_MOUSE
θ value	8.36355e-22 (rank : 47)	NC score	0.578795 (rank : 50)
Query Neighborhood Hits	264	Target Neighborhood Hits	179	Shared Neighborhood Hits	90
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS20_HUMAN
θ value	1.86321e-21 (rank : 48)	NC score	0.593343 (rank : 47)
Query Neighborhood Hits	264	Target Neighborhood Hits	192	Shared Neighborhood Hits	99
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	4.15078e-21 (rank : 49)	NC score	0.575329 (rank : 54)
Query Neighborhood Hits	264	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS7_HUMAN
θ value	2.06002e-20 (rank : 50)	NC score	0.612348 (rank : 45)
Query Neighborhood Hits	264	Target Neighborhood Hits	169	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS5_HUMAN
θ value	2.69047e-20 (rank : 51)	NC score	0.575703 (rank : 52)
Query Neighborhood Hits	264	Target Neighborhood Hits	141	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS9_HUMAN
θ value	2.69047e-20 (rank : 52)	NC score	0.563140 (rank : 60)
Query Neighborhood Hits	264	Target Neighborhood Hits	219	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS5_MOUSE
θ value	5.99374e-20 (rank : 53)	NC score	0.588701 (rank : 48)
Query Neighborhood Hits	264	Target Neighborhood Hits	147	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS15_HUMAN
θ value	7.82807e-20 (rank : 54)	NC score	0.550491 (rank : 65)
Query Neighborhood Hits	264	Target Neighborhood Hits	151	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS18_HUMAN
θ value	1.74391e-19 (rank : 55)	NC score	0.570214 (rank : 55)
Query Neighborhood Hits	264	Target Neighborhood Hits	169	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS1_MOUSE
θ value	5.07402e-19 (rank : 56)	NC score	0.568839 (rank : 56)
Query Neighborhood Hits	264	Target Neighborhood Hits	158	Shared Neighborhood Hits	82
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS1_HUMAN
θ value	1.24977e-17 (rank : 57)	NC score	0.553286 (rank : 64)
Query Neighborhood Hits	264	Target Neighborhood Hits	159	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS12_HUMAN
θ value	1.80466e-16 (rank : 58)	NC score	0.576022 (rank : 51)
Query Neighborhood Hits	264	Target Neighborhood Hits	251	Shared Neighborhood Hits	84
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS18_MOUSE
θ value	6.85773e-16 (rank : 59)	NC score	0.554243 (rank : 63)
Query Neighborhood Hits	264	Target Neighborhood Hits	163	Shared Neighborhood Hits	85
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS19_MOUSE
θ value	6.85773e-16 (rank : 60)	NC score	0.564876 (rank : 58)
Query Neighborhood Hits	264	Target Neighborhood Hits	188	Shared Neighborhood Hits	85
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS8_MOUSE
θ value	4.44505e-15 (rank : 61)	NC score	0.502367 (rank : 69)
Query Neighborhood Hits	264	Target Neighborhood Hits	139	Shared Neighborhood Hits	74
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS3_HUMAN
θ value	5.8054e-15 (rank : 62)	NC score	0.563141 (rank : 59)
Query Neighborhood Hits	264	Target Neighborhood Hits	179	Shared Neighborhood Hits	86
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS19_HUMAN
θ value	7.58209e-15 (rank : 63)	NC score	0.566097 (rank : 57)
Query Neighborhood Hits	264	Target Neighborhood Hits	203	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS12_MOUSE
θ value	1.29331e-14 (rank : 64)	NC score	0.575627 (rank : 53)
Query Neighborhood Hits	264	Target Neighborhood Hits	220	Shared Neighborhood Hits	95
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS8_HUMAN
θ value	1.29331e-14 (rank : 65)	NC score	0.529357 (rank : 66)
Query Neighborhood Hits	264	Target Neighborhood Hits	145	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS4_HUMAN
θ value	3.18553e-13 (rank : 66)	NC score	0.477347 (rank : 71)
Query Neighborhood Hits	264	Target Neighborhood Hits	138	Shared Neighborhood Hits	77
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
θ value	1.2105e-12 (rank : 67)	NC score	0.486344 (rank : 70)
Query Neighborhood Hits	264	Target Neighborhood Hits	145	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS6_HUMAN
θ value	2.0648e-12 (rank : 68)	NC score	0.601020 (rank : 46)
Query Neighborhood Hits	264	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS2_HUMAN
θ value	4.59992e-12 (rank : 69)	NC score	0.524156 (rank : 67)
Query Neighborhood Hits	264	Target Neighborhood Hits	179	Shared Neighborhood Hits	86
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS17_HUMAN
θ value	7.84624e-12 (rank : 70)	NC score	0.561655 (rank : 61)
Query Neighborhood Hits	264	Target Neighborhood Hits	194	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS2_MOUSE
θ value	2.28291e-11 (rank : 71)	NC score	0.521698 (rank : 68)
Query Neighborhood Hits	264	Target Neighborhood Hits	179	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

TENX_HUMAN
θ value	8.97725e-08 (rank : 72)	NC score	0.201982 (rank : 89)
Query Neighborhood Hits	264	Target Neighborhood Hits	789	Shared Neighborhood Hits	185
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NOTC4_HUMAN
θ value	2.61198e-07 (rank : 73)	NC score	0.160267 (rank : 122)
Query Neighborhood Hits	264	Target Neighborhood Hits	905	Shared Neighborhood Hits	178
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

MEGF6_HUMAN
θ value	1.69304e-06 (rank : 74)	NC score	0.182571 (rank : 101)
Query Neighborhood Hits	264	Target Neighborhood Hits	671	Shared Neighborhood Hits	184
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

ATS13_HUMAN
θ value	2.88788e-06 (rank : 75)	NC score	0.395307 (rank : 73)
Query Neighborhood Hits	264	Target Neighborhood Hits	238	Shared Neighborhood Hits	79
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

JAG2_HUMAN
θ value	2.88788e-06 (rank : 76)	NC score	0.190800 (rank : 93)
Query Neighborhood Hits	264	Target Neighborhood Hits	491	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

STAB1_HUMAN
θ value	1.87187e-05 (rank : 77)	NC score	0.136182 (rank : 172)
Query Neighborhood Hits	264	Target Neighborhood Hits	546	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

NOTC3_MOUSE
θ value	4.1701e-05 (rank : 78)	NC score	0.160307 (rank : 121)
Query Neighborhood Hits	264	Target Neighborhood Hits	975	Shared Neighborhood Hits	183
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ATS13_MOUSE
θ value	0.000121331 (rank : 79)	NC score	0.395450 (rank : 72)
Query Neighborhood Hits	264	Target Neighborhood Hits	227	Shared Neighborhood Hits	88
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

NOTC1_MOUSE
θ value	0.000158464 (rank : 80)	NC score	0.178519 (rank : 105)
Query Neighborhood Hits	264	Target Neighborhood Hits	916	Shared Neighborhood Hits	178
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FRAS1_HUMAN
θ value	0.000602161 (rank : 81)	NC score	0.132098 (rank : 180)
Query Neighborhood Hits	264	Target Neighborhood Hits	759	Shared Neighborhood Hits	166
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NOTC3_HUMAN
θ value	0.000602161 (rank : 82)	NC score	0.159358 (rank : 127)
Query Neighborhood Hits	264	Target Neighborhood Hits	1062	Shared Neighborhood Hits	185
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TENA_MOUSE
θ value	0.00175202 (rank : 83)	NC score	0.202893 (rank : 87)
Query Neighborhood Hits	264	Target Neighborhood Hits	596	Shared Neighborhood Hits	175
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

SREC_HUMAN
θ value	0.00298849 (rank : 84)	NC score	0.170421 (rank : 109)
Query Neighborhood Hits	264	Target Neighborhood Hits	645	Shared Neighborhood Hits	176
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

FBN2_MOUSE
θ value	0.00390308 (rank : 85)	NC score	0.160050 (rank : 123)
Query Neighborhood Hits	264	Target Neighborhood Hits	549	Shared Neighborhood Hits	185
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LAMB2_MOUSE
θ value	0.00390308 (rank : 86)	NC score	0.097311 (rank : 242)
Query Neighborhood Hits	264	Target Neighborhood Hits	722	Shared Neighborhood Hits	141
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

TRBM_HUMAN
θ value	0.00509761 (rank : 87)	NC score	0.101079 (rank : 227)
Query Neighborhood Hits	264	Target Neighborhood Hits	339	Shared Neighborhood Hits	118
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CRUM2_HUMAN
θ value	0.00869519 (rank : 88)	NC score	0.144022 (rank : 155)
Query Neighborhood Hits	264	Target Neighborhood Hits	453	Shared Neighborhood Hits	152
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FBN2_HUMAN
θ value	0.00869519 (rank : 89)	NC score	0.154339 (rank : 132)
Query Neighborhood Hits	264	Target Neighborhood Hits	560	Shared Neighborhood Hits	185
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

NOTC1_HUMAN
θ value	0.00869519 (rank : 90)	NC score	0.178647 (rank : 104)
Query Neighborhood Hits	264	Target Neighborhood Hits	906	Shared Neighborhood Hits	181
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SREC2_MOUSE
θ value	0.00869519 (rank : 91)	NC score	0.167654 (rank : 115)
Query Neighborhood Hits	264	Target Neighborhood Hits	605	Shared Neighborhood Hits	168
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

C1QR1_HUMAN
θ value	0.0113563 (rank : 92)	NC score	0.143461 (rank : 158)
Query Neighborhood Hits	264	Target Neighborhood Hits	493	Shared Neighborhood Hits	142
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

FBN1_HUMAN
θ value	0.0113563 (rank : 93)	NC score	0.158157 (rank : 129)
Query Neighborhood Hits	264	Target Neighborhood Hits	557	Shared Neighborhood Hits	178
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP4_MOUSE
θ value	0.0148317 (rank : 94)	NC score	0.134966 (rank : 175)
Query Neighborhood Hits	264	Target Neighborhood Hits	607	Shared Neighborhood Hits	166
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LAMA1_HUMAN
θ value	0.0193708 (rank : 95)	NC score	0.088285 (rank : 286)
Query Neighborhood Hits	264	Target Neighborhood Hits	804	Shared Neighborhood Hits	144
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

FBN1_MOUSE
θ value	0.0252991 (rank : 96)	NC score	0.159594 (rank : 124)
Query Neighborhood Hits	264	Target Neighborhood Hits	563	Shared Neighborhood Hits	178
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

SREC2_HUMAN
θ value	0.0252991 (rank : 97)	NC score	0.166394 (rank : 117)
Query Neighborhood Hits	264	Target Neighborhood Hits	645	Shared Neighborhood Hits	168
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

DLL3_HUMAN
θ value	0.0330416 (rank : 98)	NC score	0.151987 (rank : 139)
Query Neighborhood Hits	264	Target Neighborhood Hits	419	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

JAG1_HUMAN
θ value	0.0330416 (rank : 99)	NC score	0.185138 (rank : 98)
Query Neighborhood Hits	264	Target Neighborhood Hits	514	Shared Neighborhood Hits	177
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

KRA54_HUMAN
θ value	0.0330416 (rank : 100)	NC score	0.242042 (rank : 81)
Query Neighborhood Hits	264	Target Neighborhood Hits	270	Shared Neighborhood Hits	129
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

NOTC2_HUMAN
θ value	0.0330416 (rank : 101)	NC score	0.177797 (rank : 107)
Query Neighborhood Hits	264	Target Neighborhood Hits	1113	Shared Neighborhood Hits	197
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

STAB1_MOUSE
θ value	0.0330416 (rank : 102)	NC score	0.147365 (rank : 147)
Query Neighborhood Hits	264	Target Neighborhood Hits	566	Shared Neighborhood Hits	171
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

DLK_HUMAN
θ value	0.0431538 (rank : 103)	NC score	0.143444 (rank : 159)
Query Neighborhood Hits	264	Target Neighborhood Hits	401	Shared Neighborhood Hits	163
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

NELL2_HUMAN
θ value	0.0431538 (rank : 104)	NC score	0.158968 (rank : 128)
Query Neighborhood Hits	264	Target Neighborhood Hits	449	Shared Neighborhood Hits	158
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	0.0431538 (rank : 105)	NC score	0.148004 (rank : 144)
Query Neighborhood Hits	264	Target Neighborhood Hits	436	Shared Neighborhood Hits	158
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NOTC4_MOUSE
θ value	0.0563607 (rank : 106)	NC score	0.149974 (rank : 142)
Query Neighborhood Hits	264	Target Neighborhood Hits	872	Shared Neighborhood Hits	179
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

DLL4_MOUSE
θ value	0.0736092 (rank : 107)	NC score	0.159364 (rank : 126)
Query Neighborhood Hits	264	Target Neighborhood Hits	440	Shared Neighborhood Hits	162
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

K1802_HUMAN
θ value	0.0736092 (rank : 108)	NC score	0.007724 (rank : 441)
Query Neighborhood Hits	264	Target Neighborhood Hits	1378	Shared Neighborhood Hits	29
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KRA59_HUMAN
θ value	0.0961366 (rank : 109)	NC score	0.177862 (rank : 106)
Query Neighborhood Hits	264	Target Neighborhood Hits	310	Shared Neighborhood Hits	120
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMC2_MOUSE
θ value	0.0961366 (rank : 110)	NC score	0.091058 (rank : 273)
Query Neighborhood Hits	264	Target Neighborhood Hits	614	Shared Neighborhood Hits	137
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

WIF1_MOUSE
θ value	0.0961366 (rank : 111)	NC score	0.193571 (rank : 92)
Query Neighborhood Hits	264	Target Neighborhood Hits	393	Shared Neighborhood Hits	166
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CD97_MOUSE
θ value	0.125558 (rank : 112)	NC score	0.072711 (rank : 340)
Query Neighborhood Hits	264	Target Neighborhood Hits	295	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CSPG2_MOUSE
θ value	0.125558 (rank : 113)	NC score	0.070707 (rank : 347)
Query Neighborhood Hits	264	Target Neighborhood Hits	711	Shared Neighborhood Hits	115
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

LRP1B_MOUSE
θ value	0.125558 (rank : 114)	NC score	0.143872 (rank : 156)
Query Neighborhood Hits	264	Target Neighborhood Hits	606	Shared Neighborhood Hits	184
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

NOTC2_MOUSE
θ value	0.125558 (rank : 115)	NC score	0.173228 (rank : 108)
Query Neighborhood Hits	264	Target Neighborhood Hits	1069	Shared Neighborhood Hits	197
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

AGRIN_HUMAN
θ value	0.163984 (rank : 116)	NC score	0.144475 (rank : 153)
Query Neighborhood Hits	264	Target Neighborhood Hits	582	Shared Neighborhood Hits	168
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CRUM1_MOUSE
θ value	0.163984 (rank : 117)	NC score	0.131508 (rank : 181)
Query Neighborhood Hits	264	Target Neighborhood Hits	444	Shared Neighborhood Hits	150
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

FBN3_HUMAN
θ value	0.163984 (rank : 118)	NC score	0.151147 (rank : 140)
Query Neighborhood Hits	264	Target Neighborhood Hits	543	Shared Neighborhood Hits	174
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

KRA53_HUMAN
θ value	0.163984 (rank : 119)	NC score	0.249410 (rank : 80)
Query Neighborhood Hits	264	Target Neighborhood Hits	331	Shared Neighborhood Hits	148
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

DLL1_MOUSE
θ value	0.21417 (rank : 120)	NC score	0.178903 (rank : 103)
Query Neighborhood Hits	264	Target Neighborhood Hits	456	Shared Neighborhood Hits	169
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

JAG1_MOUSE
θ value	0.21417 (rank : 121)	NC score	0.183464 (rank : 99)
Query Neighborhood Hits	264	Target Neighborhood Hits	518	Shared Neighborhood Hits	177
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

K1802_MOUSE
θ value	0.21417 (rank : 122)	NC score	0.009023 (rank : 437)
Query Neighborhood Hits	264	Target Neighborhood Hits	1596	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KR104_HUMAN
θ value	0.21417 (rank : 123)	NC score	0.205238 (rank : 85)
Query Neighborhood Hits	264	Target Neighborhood Hits	313	Shared Neighborhood Hits	138
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR106_HUMAN
θ value	0.21417 (rank : 124)	NC score	0.201856 (rank : 90)
Query Neighborhood Hits	264	Target Neighborhood Hits	347	Shared Neighborhood Hits	157
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

NTNG2_MOUSE
θ value	0.21417 (rank : 125)	NC score	0.097577 (rank : 239)
Query Neighborhood Hits	264	Target Neighborhood Hits	276	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

SLIT1_HUMAN
θ value	0.21417 (rank : 126)	NC score	0.091521 (rank : 270)
Query Neighborhood Hits	264	Target Neighborhood Hits	700	Shared Neighborhood Hits	147
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

WIF1_HUMAN
θ value	0.21417 (rank : 127)	NC score	0.185212 (rank : 97)
Query Neighborhood Hits	264	Target Neighborhood Hits	392	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CSPG2_HUMAN
θ value	0.279714 (rank : 128)	NC score	0.068481 (rank : 355)
Query Neighborhood Hits	264	Target Neighborhood Hits	681	Shared Neighborhood Hits	115
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

DKK4_HUMAN
θ value	0.279714 (rank : 129)	NC score	0.029873 (rank : 412)
Query Neighborhood Hits	264	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBT3, Q9Y4C3	Gene names	DKK4
Domain Architecture
Description	Dickkopf-related protein 4 precursor (Dkk-4) (Dickkopf-4) (hDkk-4) [Contains: Dickkopf-related protein 4 short form].

KR107_HUMAN
θ value	0.279714 (rank : 130)	NC score	0.187975 (rank : 95)
Query Neighborhood Hits	264	Target Neighborhood Hits	330	Shared Neighborhood Hits	146
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA55_HUMAN
θ value	0.279714 (rank : 131)	NC score	0.166684 (rank : 116)
Query Neighborhood Hits	264	Target Neighborhood Hits	257	Shared Neighborhood Hits	116
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LRP2_HUMAN
θ value	0.279714 (rank : 132)	NC score	0.127228 (rank : 185)
Query Neighborhood Hits	264	Target Neighborhood Hits	573	Shared Neighborhood Hits	178
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

SLIT3_MOUSE
θ value	0.279714 (rank : 133)	NC score	0.088061 (rank : 288)
Query Neighborhood Hits	264	Target Neighborhood Hits	700	Shared Neighborhood Hits	148
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TENA_HUMAN
θ value	0.279714 (rank : 134)	NC score	0.190086 (rank : 94)
Query Neighborhood Hits	264	Target Neighborhood Hits	631	Shared Neighborhood Hits	174
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

DLL1_HUMAN
θ value	0.365318 (rank : 135)	NC score	0.167805 (rank : 114)
Query Neighborhood Hits	264	Target Neighborhood Hits	455	Shared Neighborhood Hits	164
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

EGFL8_MOUSE
θ value	0.365318 (rank : 136)	NC score	0.131193 (rank : 182)
Query Neighborhood Hits	264	Target Neighborhood Hits	266	Shared Neighborhood Hits	112
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	0.365318 (rank : 137)	NC score	0.134028 (rank : 176)
Query Neighborhood Hits	264	Target Neighborhood Hits	365	Shared Neighborhood Hits	146
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	0.365318 (rank : 138)	NC score	0.137190 (rank : 170)
Query Neighborhood Hits	264	Target Neighborhood Hits	379	Shared Neighborhood Hits	148
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_MOUSE
θ value	0.365318 (rank : 139)	NC score	0.080020 (rank : 320)
Query Neighborhood Hits	264	Target Neighborhood Hits	358	Shared Neighborhood Hits	119
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

HHIP_MOUSE
θ value	0.365318 (rank : 140)	NC score	0.133335 (rank : 177)
Query Neighborhood Hits	264	Target Neighborhood Hits	219	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA47_HUMAN
θ value	0.365318 (rank : 141)	NC score	0.124581 (rank : 187)
Query Neighborhood Hits	264	Target Neighborhood Hits	204	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

LAMA3_MOUSE
θ value	0.365318 (rank : 142)	NC score	0.087982 (rank : 289)
Query Neighborhood Hits	264	Target Neighborhood Hits	859	Shared Neighborhood Hits	156
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LTBP3_MOUSE
θ value	0.365318 (rank : 143)	NC score	0.138140 (rank : 168)
Query Neighborhood Hits	264	Target Neighborhood Hits	475	Shared Neighborhood Hits	167
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

SPN90_MOUSE
θ value	0.365318 (rank : 144)	NC score	0.012666 (rank : 431)
Query Neighborhood Hits	264	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SSPO_MOUSE
θ value	0.365318 (rank : 145)	NC score	0.196726 (rank : 91)
Query Neighborhood Hits	264	Target Neighborhood Hits	800	Shared Neighborhood Hits	196
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STAB2_MOUSE
θ value	0.365318 (rank : 146)	NC score	0.144674 (rank : 151)
Query Neighborhood Hits	264	Target Neighborhood Hits	528	Shared Neighborhood Hits	174
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KR10C_HUMAN
θ value	0.47712 (rank : 147)	NC score	0.168271 (rank : 113)
Query Neighborhood Hits	264	Target Neighborhood Hits	219	Shared Neighborhood Hits	113
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR511_HUMAN
θ value	0.47712 (rank : 148)	NC score	0.168386 (rank : 112)
Query Neighborhood Hits	264	Target Neighborhood Hits	231	Shared Neighborhood Hits	98
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA56_HUMAN
θ value	0.47712 (rank : 149)	NC score	0.179405 (rank : 102)
Query Neighborhood Hits	264	Target Neighborhood Hits	207	Shared Neighborhood Hits	101
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

NELL1_HUMAN
θ value	0.47712 (rank : 150)	NC score	0.128483 (rank : 184)
Query Neighborhood Hits	264	Target Neighborhood Hits	451	Shared Neighborhood Hits	153
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SLIT1_MOUSE
θ value	0.47712 (rank : 151)	NC score	0.088539 (rank : 284)
Query Neighborhood Hits	264	Target Neighborhood Hits	715	Shared Neighborhood Hits	149
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

CELR3_HUMAN
θ value	0.62314 (rank : 152)	NC score	0.044918 (rank : 406)
Query Neighborhood Hits	264	Target Neighborhood Hits	680	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

DLL4_HUMAN
θ value	0.62314 (rank : 153)	NC score	0.144510 (rank : 152)
Query Neighborhood Hits	264	Target Neighborhood Hits	435	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FA12_HUMAN
θ value	0.62314 (rank : 154)	NC score	0.032813 (rank : 410)
Query Neighborhood Hits	264	Target Neighborhood Hits	425	Shared Neighborhood Hits	96
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FBLN2_MOUSE
θ value	0.62314 (rank : 155)	NC score	0.106802 (rank : 218)
Query Neighborhood Hits	264	Target Neighborhood Hits	505	Shared Neighborhood Hits	134
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

HHIP_HUMAN
θ value	0.62314 (rank : 156)	NC score	0.152576 (rank : 138)
Query Neighborhood Hits	264	Target Neighborhood Hits	249	Shared Neighborhood Hits	145
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB4_HUMAN
θ value	0.62314 (rank : 157)	NC score	0.094667 (rank : 254)
Query Neighborhood Hits	264	Target Neighborhood Hits	458	Shared Neighborhood Hits	139
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

LAMA5_MOUSE
θ value	0.62314 (rank : 158)	NC score	0.096328 (rank : 248)
Query Neighborhood Hits	264	Target Neighborhood Hits	828	Shared Neighborhood Hits	150
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LTBP3_HUMAN
θ value	0.62314 (rank : 159)	NC score	0.138866 (rank : 166)
Query Neighborhood Hits	264	Target Neighborhood Hits	502	Shared Neighborhood Hits	162
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

SLIT3_HUMAN
θ value	0.62314 (rank : 160)	NC score	0.083116 (rank : 307)
Query Neighborhood Hits	264	Target Neighborhood Hits	682	Shared Neighborhood Hits	139
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

EGFL8_HUMAN
θ value	0.813845 (rank : 161)	NC score	0.116624 (rank : 198)
Query Neighborhood Hits	264	Target Neighborhood Hits	270	Shared Neighborhood Hits	111
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

IRS2_HUMAN
θ value	0.813845 (rank : 162)	NC score	0.008086 (rank : 440)
Query Neighborhood Hits	264	Target Neighborhood Hits	262	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

JAG2_MOUSE
θ value	0.813845 (rank : 163)	NC score	0.187337 (rank : 96)
Query Neighborhood Hits	264	Target Neighborhood Hits	504	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KRA58_HUMAN
θ value	0.813845 (rank : 164)	NC score	0.252476 (rank : 79)
Query Neighborhood Hits	264	Target Neighborhood Hits	324	Shared Neighborhood Hits	145
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMC2_HUMAN
θ value	0.813845 (rank : 165)	NC score	0.093598 (rank : 260)
Query Neighborhood Hits	264	Target Neighborhood Hits	715	Shared Neighborhood Hits	133
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LRP8_MOUSE
θ value	0.813845 (rank : 166)	NC score	0.086640 (rank : 293)
Query Neighborhood Hits	264	Target Neighborhood Hits	385	Shared Neighborhood Hits	124
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_MOUSE
θ value	0.813845 (rank : 167)	NC score	0.139948 (rank : 163)
Query Neighborhood Hits	264	Target Neighborhood Hits	514	Shared Neighborhood Hits	165
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.813845 (rank : 168)	NC score	0.139509 (rank : 165)
Query Neighborhood Hits	264	Target Neighborhood Hits	479	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PRP1_HUMAN
θ value	0.813845 (rank : 169)	NC score	0.013666 (rank : 427)
Query Neighborhood Hits	264	Target Neighborhood Hits	385	Shared Neighborhood Hits	11
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RELN_MOUSE
θ value	0.813845 (rank : 170)	NC score	0.157595 (rank : 130)
Query Neighborhood Hits	264	Target Neighborhood Hits	235	Shared Neighborhood Hits	120
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

KR510_HUMAN
θ value	1.06291 (rank : 171)	NC score	0.182827 (rank : 100)
Query Neighborhood Hits	264	Target Neighborhood Hits	217	Shared Neighborhood Hits	104
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

MTR1L_HUMAN
θ value	1.06291 (rank : 172)	NC score	-0.006425 (rank : 464)
Query Neighborhood Hits	264	Target Neighborhood Hits	1180	Shared Neighborhood Hits	15
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

RN167_HUMAN
θ value	1.06291 (rank : 173)	NC score	0.011823 (rank : 434)
Query Neighborhood Hits	264	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

SF01_HUMAN
θ value	1.06291 (rank : 174)	NC score	0.019088 (rank : 422)
Query Neighborhood Hits	264	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	1.06291 (rank : 175)	NC score	0.013402 (rank : 428)
Query Neighborhood Hits	264	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

DLL3_MOUSE
θ value	1.38821 (rank : 176)	NC score	0.159479 (rank : 125)
Query Neighborhood Hits	264	Target Neighborhood Hits	399	Shared Neighborhood Hits	147
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

FRAS1_MOUSE
θ value	1.38821 (rank : 177)	NC score	0.123466 (rank : 190)
Query Neighborhood Hits	264	Target Neighborhood Hits	747	Shared Neighborhood Hits	167
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GRN_HUMAN
θ value	1.38821 (rank : 178)	NC score	0.096948 (rank : 243)
Query Neighborhood Hits	264	Target Neighborhood Hits	268	Shared Neighborhood Hits	113
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

ITB5_MOUSE
θ value	1.38821 (rank : 179)	NC score	0.100860 (rank : 229)
Query Neighborhood Hits	264	Target Neighborhood Hits	329	Shared Neighborhood Hits	143
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

KRA51_HUMAN
θ value	1.38821 (rank : 180)	NC score	0.202197 (rank : 88)
Query Neighborhood Hits	264	Target Neighborhood Hits	288	Shared Neighborhood Hits	138
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

NAGPA_HUMAN
θ value	1.38821 (rank : 181)	NC score	0.163900 (rank : 118)
Query Neighborhood Hits	264	Target Neighborhood Hits	282	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

PCSK5_MOUSE
θ value	1.38821 (rank : 182)	NC score	0.114616 (rank : 203)
Query Neighborhood Hits	264	Target Neighborhood Hits	613	Shared Neighborhood Hits	159
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

RELN_HUMAN
θ value	1.38821 (rank : 183)	NC score	0.149359 (rank : 143)
Query Neighborhood Hits	264	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RN167_MOUSE
θ value	1.38821 (rank : 184)	NC score	0.013237 (rank : 430)
Query Neighborhood Hits	264	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

SF3A2_HUMAN
θ value	1.38821 (rank : 185)	NC score	0.017258 (rank : 423)
Query Neighborhood Hits	264	Target Neighborhood Hits	263	Shared Neighborhood Hits	14
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

STAB2_HUMAN
θ value	1.38821 (rank : 186)	NC score	0.147775 (rank : 145)
Query Neighborhood Hits	264	Target Neighborhood Hits	534	Shared Neighborhood Hits	171
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TAOK1_MOUSE
θ value	1.38821 (rank : 187)	NC score	-0.009325 (rank : 466)
Query Neighborhood Hits	264	Target Neighborhood Hits	1720	Shared Neighborhood Hits	10
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

ZAN_MOUSE
θ value	1.38821 (rank : 188)	NC score	0.152648 (rank : 137)
Query Neighborhood Hits	264	Target Neighborhood Hits	808	Shared Neighborhood Hits	182
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CNOT3_HUMAN
θ value	1.81305 (rank : 189)	NC score	0.005511 (rank : 447)
Query Neighborhood Hits	264	Target Neighborhood Hits	425	Shared Neighborhood Hits	8
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DLK_MOUSE
θ value	1.81305 (rank : 190)	NC score	0.138728 (rank : 167)
Query Neighborhood Hits	264	Target Neighborhood Hits	374	Shared Neighborhood Hits	155
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

LAMA2_MOUSE
θ value	1.81305 (rank : 191)	NC score	0.077339 (rank : 325)
Query Neighborhood Hits	264	Target Neighborhood Hits	1198	Shared Neighborhood Hits	152
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_HUMAN
θ value	1.81305 (rank : 192)	NC score	0.078966 (rank : 323)
Query Neighborhood Hits	264	Target Neighborhood Hits	922	Shared Neighborhood Hits	139
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	1.81305 (rank : 193)	NC score	0.081741 (rank : 308)
Query Neighborhood Hits	264	Target Neighborhood Hits	856	Shared Neighborhood Hits	138
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MMP7_HUMAN
θ value	1.81305 (rank : 194)	NC score	0.013267 (rank : 429)
Query Neighborhood Hits	264	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

SALL3_HUMAN
θ value	1.81305 (rank : 195)	NC score	-0.006544 (rank : 465)
Query Neighborhood Hits	264	Target Neighborhood Hits	1066	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

DNER_MOUSE
θ value	2.36792 (rank : 196)	NC score	0.161003 (rank : 120)
Query Neighborhood Hits	264	Target Neighborhood Hits	413	Shared Neighborhood Hits	152
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

FOXC2_HUMAN
θ value	2.36792 (rank : 197)	NC score	0.000086 (rank : 454)
Query Neighborhood Hits	264	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

HXA10_MOUSE
θ value	2.36792 (rank : 198)	NC score	-0.001949 (rank : 459)
Query Neighborhood Hits	264	Target Neighborhood Hits	365	Shared Neighborhood Hits	5
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

ITB2_MOUSE
θ value	2.36792 (rank : 199)	NC score	0.117742 (rank : 196)
Query Neighborhood Hits	264	Target Neighborhood Hits	326	Shared Neighborhood Hits	154
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KR10B_HUMAN
θ value	2.36792 (rank : 200)	NC score	0.153069 (rank : 136)
Query Neighborhood Hits	264	Target Neighborhood Hits	269	Shared Neighborhood Hits	124
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR414_HUMAN
θ value	2.36792 (rank : 201)	NC score	0.115591 (rank : 200)
Query Neighborhood Hits	264	Target Neighborhood Hits	199	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

NET4_MOUSE
θ value	2.36792 (rank : 202)	NC score	0.050185 (rank : 405)
Query Neighborhood Hits	264	Target Neighborhood Hits	180	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

PO121_MOUSE
θ value	2.36792 (rank : 203)	NC score	0.006681 (rank : 445)
Query Neighborhood Hits	264	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

TAOK1_HUMAN
θ value	2.36792 (rank : 204)	NC score	-0.009479 (rank : 467)
Query Neighborhood Hits	264	Target Neighborhood Hits	1734	Shared Neighborhood Hits	10
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TENN_MOUSE
θ value	2.36792 (rank : 205)	NC score	0.121965 (rank : 192)
Query Neighborhood Hits	264	Target Neighborhood Hits	484	Shared Neighborhood Hits	161
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TIE1_MOUSE
θ value	2.36792 (rank : 206)	NC score	0.039002 (rank : 408)
Query Neighborhood Hits	264	Target Neighborhood Hits	1266	Shared Neighborhood Hits	142
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

KRA57_HUMAN
θ value	3.0926 (rank : 207)	NC score	0.239301 (rank : 82)
Query Neighborhood Hits	264	Target Neighborhood Hits	269	Shared Neighborhood Hits	133
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

LAMA5_HUMAN
θ value	3.0926 (rank : 208)	NC score	0.095293 (rank : 252)
Query Neighborhood Hits	264	Target Neighborhood Hits	976	Shared Neighborhood Hits	162
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LRP1_HUMAN
θ value	3.0926 (rank : 209)	NC score	0.145891 (rank : 149)
Query Neighborhood Hits	264	Target Neighborhood Hits	617	Shared Neighborhood Hits	185
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LTB1S_HUMAN
θ value	3.0926 (rank : 210)	NC score	0.139721 (rank : 164)
Query Neighborhood Hits	264	Target Neighborhood Hits	502	Shared Neighborhood Hits	158
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MEGF9_HUMAN
θ value	3.0926 (rank : 211)	NC score	0.115761 (rank : 199)
Query Neighborhood Hits	264	Target Neighborhood Hits	557	Shared Neighborhood Hits	146
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MMP1A_MOUSE
θ value	3.0926 (rank : 212)	NC score	0.012412 (rank : 432)
Query Neighborhood Hits	264	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

PCDA9_HUMAN
θ value	3.0926 (rank : 213)	NC score	-0.001738 (rank : 457)
Query Neighborhood Hits	264	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

PS1C2_HUMAN
θ value	3.0926 (rank : 214)	NC score	0.021465 (rank : 421)
Query Neighborhood Hits	264	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PS1C2_MOUSE
θ value	3.0926 (rank : 215)	NC score	0.025369 (rank : 417)
Query Neighborhood Hits	264	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

RON_MOUSE
θ value	3.0926 (rank : 216)	NC score	-0.005654 (rank : 463)
Query Neighborhood Hits	264	Target Neighborhood Hits	836	Shared Neighborhood Hits	11
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

TIE2_HUMAN
θ value	3.0926 (rank : 217)	NC score	0.025312 (rank : 418)
Query Neighborhood Hits	264	Target Neighborhood Hits	1192	Shared Neighborhood Hits	125
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

YLPM1_HUMAN
θ value	3.0926 (rank : 218)	NC score	0.003985 (rank : 448)
Query Neighborhood Hits	264	Target Neighborhood Hits	670	Shared Neighborhood Hits	13
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

HAIR_MOUSE
θ value	4.03905 (rank : 219)	NC score	0.005715 (rank : 446)
Query Neighborhood Hits	264	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

KCNKH_HUMAN
θ value	4.03905 (rank : 220)	NC score	0.002831 (rank : 451)
Query Neighborhood Hits	264	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

LRP1B_HUMAN
θ value	4.03905 (rank : 221)	NC score	0.147645 (rank : 146)
Query Neighborhood Hits	264	Target Neighborhood Hits	602	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LTB1L_HUMAN
θ value	4.03905 (rank : 222)	NC score	0.137820 (rank : 169)
Query Neighborhood Hits	264	Target Neighborhood Hits	553	Shared Neighborhood Hits	168
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MMP1_HUMAN
θ value	4.03905 (rank : 223)	NC score	0.008491 (rank : 438)
Query Neighborhood Hits	264	Target Neighborhood Hits	55	Shared Neighborhood Hits	13
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP28_HUMAN
θ value	4.03905 (rank : 224)	NC score	0.009751 (rank : 436)
Query Neighborhood Hits	264	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

NAGPA_MOUSE
θ value	4.03905 (rank : 225)	NC score	0.203889 (rank : 86)
Query Neighborhood Hits	264	Target Neighborhood Hits	308	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

PER1_HUMAN
θ value	4.03905 (rank : 226)	NC score	0.003529 (rank : 449)
Query Neighborhood Hits	264	Target Neighborhood Hits	215	Shared Neighborhood Hits	9
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PRG4_HUMAN
θ value	4.03905 (rank : 227)	NC score	0.010436 (rank : 435)
Query Neighborhood Hits	264	Target Neighborhood Hits	764	Shared Neighborhood Hits	35
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SLIT2_MOUSE
θ value	4.03905 (rank : 228)	NC score	0.087593 (rank : 290)
Query Neighborhood Hits	264	Target Neighborhood Hits	684	Shared Neighborhood Hits	142
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TIE1_HUMAN
θ value	4.03905 (rank : 229)	NC score	0.039351 (rank : 407)
Query Neighborhood Hits	264	Target Neighborhood Hits	1241	Shared Neighborhood Hits	141
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

COLQ_HUMAN
θ value	5.27518 (rank : 230)	NC score	0.027911 (rank : 414)
Query Neighborhood Hits	264	Target Neighborhood Hits	193	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

COX11_MOUSE
θ value	5.27518 (rank : 231)	NC score	0.007247 (rank : 444)
Query Neighborhood Hits	264	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P8I6	Gene names	Cox11
Domain Architecture	No domain graphic available
Description	Cytochrome c oxidase assembly protein COX11, mitochondrial precursor.

IQEC2_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.003058 (rank : 450)
Query Neighborhood Hits	264	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	5.27518 (rank : 233)	NC score	0.002523 (rank : 453)
Query Neighborhood Hits	264	Target Neighborhood Hits	417	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

JIP3_HUMAN
θ value	5.27518 (rank : 234)	NC score	-0.000795 (rank : 455)
Query Neighborhood Hits	264	Target Neighborhood Hits	1039	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

KRA52_HUMAN
θ value	5.27518 (rank : 235)	NC score	0.211488 (rank : 84)
Query Neighborhood Hits	264	Target Neighborhood Hits	236	Shared Neighborhood Hits	115
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA93_HUMAN
θ value	5.27518 (rank : 236)	NC score	0.153503 (rank : 134)
Query Neighborhood Hits	264	Target Neighborhood Hits	203	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

MMP1B_MOUSE
θ value	5.27518 (rank : 237)	NC score	0.014162 (rank : 426)
Query Neighborhood Hits	264	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

OC90_MOUSE
θ value	5.27518 (rank : 238)	NC score	0.036432 (rank : 409)
Query Neighborhood Hits	264	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0L3, Q9CZ60, Q9Z225	Gene names	Oc90, Onc-95, Pla2ll
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Otoconin-95) (Oc95).

PAPPA_MOUSE
θ value	5.27518 (rank : 239)	NC score	0.023376 (rank : 419)
Query Neighborhood Hits	264	Target Neighborhood Hits	153	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

DNER_HUMAN
θ value	6.88961 (rank : 240)	NC score	0.169688 (rank : 110)
Query Neighborhood Hits	264	Target Neighborhood Hits	460	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

HYAL3_MOUSE
θ value	6.88961 (rank : 241)	NC score	0.028947 (rank : 413)
Query Neighborhood Hits	264	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

KRA92_HUMAN
θ value	6.88961 (rank : 242)	NC score	0.113384 (rank : 206)
Query Neighborhood Hits	264	Target Neighborhood Hits	198	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LCE5A_HUMAN
θ value	6.88961 (rank : 243)	NC score	0.032753 (rank : 411)
Query Neighborhood Hits	264	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LYAM2_MOUSE
θ value	6.88961 (rank : 244)	NC score	0.061700 (rank : 371)
Query Neighborhood Hits	264	Target Neighborhood Hits	420	Shared Neighborhood Hits	128
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MEGF9_MOUSE
θ value	6.88961 (rank : 245)	NC score	0.095711 (rank : 250)
Query Neighborhood Hits	264	Target Neighborhood Hits	896	Shared Neighborhood Hits	143
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MMP12_HUMAN
θ value	6.88961 (rank : 246)	NC score	0.008361 (rank : 439)
Query Neighborhood Hits	264	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

MMP7_MOUSE
θ value	6.88961 (rank : 247)	NC score	0.022472 (rank : 420)
Query Neighborhood Hits	264	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MMP8_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.007645 (rank : 442)
Query Neighborhood Hits	264	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	P22894, Q45F99	Gene names	MMP8, CLG1
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL).

MMP8_MOUSE
θ value	6.88961 (rank : 249)	NC score	0.007489 (rank : 443)
Query Neighborhood Hits	264	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

OTP_MOUSE
θ value	6.88961 (rank : 250)	NC score	-0.003471 (rank : 462)
Query Neighborhood Hits	264	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

PAPPA_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.026836 (rank : 415)
Query Neighborhood Hits	264	Target Neighborhood Hits	161	Shared Neighborhood Hits	45
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CRUM1_HUMAN
θ value	8.99809 (rank : 252)	NC score	0.135874 (rank : 173)
Query Neighborhood Hits	264	Target Neighborhood Hits	457	Shared Neighborhood Hits	157
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CUBN_HUMAN
θ value	8.99809 (rank : 253)	NC score	0.098603 (rank : 234)
Query Neighborhood Hits	264	Target Neighborhood Hits	482	Shared Neighborhood Hits	144
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

GGN_MOUSE
θ value	8.99809 (rank : 254)	NC score	0.015061 (rank : 424)
Query Neighborhood Hits	264	Target Neighborhood Hits	311	Shared Neighborhood Hits	12
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HXA3_MOUSE
θ value	8.99809 (rank : 255)	NC score	-0.003446 (rank : 461)
Query Neighborhood Hits	264	Target Neighborhood Hits	558	Shared Neighborhood Hits	11
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

K1HB_HUMAN
θ value	8.99809 (rank : 256)	NC score	-0.003038 (rank : 460)
Query Neighborhood Hits	264	Target Neighborhood Hits	470	Shared Neighborhood Hits	11
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).

KRA45_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.122358 (rank : 191)
Query Neighborhood Hits	264	Target Neighborhood Hits	194	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LAMB1_MOUSE
θ value	8.99809 (rank : 258)	NC score	0.093442 (rank : 261)
Query Neighborhood Hits	264	Target Neighborhood Hits	919	Shared Neighborhood Hits	139
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

PLD2_HUMAN
θ value	8.99809 (rank : 259)	NC score	0.002776 (rank : 452)
Query Neighborhood Hits	264	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14939, O43540, O43579, O43580, Q96BY3	Gene names	PLD2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (hPLD2).

PROC_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.025832 (rank : 416)
Query Neighborhood Hits	264	Target Neighborhood Hits	406	Shared Neighborhood Hits	101
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PZRN3_HUMAN
θ value	8.99809 (rank : 261)	NC score	-0.001757 (rank : 458)
Query Neighborhood Hits	264	Target Neighborhood Hits	461	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	8.99809 (rank : 262)	NC score	-0.001673 (rank : 456)
Query Neighborhood Hits	264	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SF3A2_MOUSE
θ value	8.99809 (rank : 263)	NC score	0.012238 (rank : 433)
Query Neighborhood Hits	264	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SPR2F_MOUSE
θ value	8.99809 (rank : 264)	NC score	0.014505 (rank : 425)
Query Neighborhood Hits	264	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

ATL1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.269378 (rank : 75)
Query Neighborhood Hits	264	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.268426 (rank : 76)
Query Neighborhood Hits	264	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL2_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.253883 (rank : 77)
Query Neighborhood Hits	264	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.253184 (rank : 78)
Query Neighborhood Hits	264	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL3_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.220328 (rank : 83)
Query Neighborhood Hits	264	Target Neighborhood Hits	414	Shared Neighborhood Hits	56
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATL5_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.279443 (rank : 74)
Query Neighborhood Hits	264	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATRN_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.067848 (rank : 358)
Query Neighborhood Hits	264	Target Neighborhood Hits	525	Shared Neighborhood Hits	138
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.076138 (rank : 327)
Query Neighborhood Hits	264	Target Neighborhood Hits	519	Shared Neighborhood Hits	140
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BAI1_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.098862 (rank : 232)
Query Neighborhood Hits	264	Target Neighborhood Hits	375	Shared Neighborhood Hits	54
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.097840 (rank : 236)
Query Neighborhood Hits	264	Target Neighborhood Hits	340	Shared Neighborhood Hits	47
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.096922 (rank : 244)
Query Neighborhood Hits	264	Target Neighborhood Hits	332	Shared Neighborhood Hits	46
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.095463 (rank : 251)
Query Neighborhood Hits	264	Target Neighborhood Hits	323	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.096196 (rank : 249)
Query Neighborhood Hits	264	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.097644 (rank : 238)
Query Neighborhood Hits	264	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

C1QR1_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.089787 (rank : 280)
Query Neighborhood Hits	264	Target Neighborhood Hits	342	Shared Neighborhood Hits	123
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD248_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.063572 (rank : 368)
Query Neighborhood Hits	264	Target Neighborhood Hits	679	Shared Neighborhood Hits	114
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.061034 (rank : 372)
Query Neighborhood Hits	264	Target Neighborhood Hits	578	Shared Neighborhood Hits	103
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.066502 (rank : 360)
Query Neighborhood Hits	264	Target Neighborhood Hits	353	Shared Neighborhood Hits	104
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CFC1_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.057187 (rank : 383)
Query Neighborhood Hits	264	Target Neighborhood Hits	148	Shared Neighborhood Hits	83
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.053358 (rank : 393)
Query Neighborhood Hits	264	Target Neighborhood Hits	125	Shared Neighborhood Hits	74
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CI094_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.155410 (rank : 131)
Query Neighborhood Hits	264	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.061801 (rank : 370)
Query Neighborhood Hits	264	Target Neighborhood Hits	266	Shared Neighborhood Hits	36
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.059091 (rank : 377)
Query Neighborhood Hits	264	Target Neighborhood Hits	282	Shared Neighborhood Hits	36
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP2_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.091135 (rank : 272)
Query Neighborhood Hits	264	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CO6_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.117731 (rank : 197)
Query Neighborhood Hits	264	Target Neighborhood Hits	331	Shared Neighborhood Hits	98
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.110883 (rank : 211)
Query Neighborhood Hits	264	Target Neighborhood Hits	278	Shared Neighborhood Hits	90
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.120198 (rank : 194)
Query Neighborhood Hits	264	Target Neighborhood Hits	200	Shared Neighborhood Hits	82
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.114416 (rank : 204)
Query Neighborhood Hits	264	Target Neighborhood Hits	182	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.093621 (rank : 259)
Query Neighborhood Hits	264	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.112253 (rank : 207)
Query Neighborhood Hits	264	Target Neighborhood Hits	224	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

COMP_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.072108 (rank : 343)
Query Neighborhood Hits	264	Target Neighborhood Hits	258	Shared Neighborhood Hits	113
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.071166 (rank : 346)
Query Neighborhood Hits	264	Target Neighborhood Hits	290	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.110706 (rank : 212)
Query Neighborhood Hits	264	Target Neighborhood Hits	441	Shared Neighborhood Hits	128
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.097451 (rank : 240)
Query Neighborhood Hits	264	Target Neighborhood Hits	524	Shared Neighborhood Hits	125
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.113758 (rank : 205)
Query Neighborhood Hits	264	Target Neighborhood Hits	362	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CSPG3_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.057339 (rank : 381)
Query Neighborhood Hits	264	Target Neighborhood Hits	676	Shared Neighborhood Hits	119
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.057215 (rank : 382)
Query Neighborhood Hits	264	Target Neighborhood Hits	657	Shared Neighborhood Hits	116
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CT127_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.055012 (rank : 388)
Query Neighborhood Hits	264	Target Neighborhood Hits	67	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CUBN_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.105624 (rank : 220)
Query Neighborhood Hits	264	Target Neighborhood Hits	477	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CYR61_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.053382 (rank : 392)
Query Neighborhood Hits	264	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

EDIL3_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.079190 (rank : 322)
Query Neighborhood Hits	264	Target Neighborhood Hits	292	Shared Neighborhood Hits	114
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.083635 (rank : 303)
Query Neighborhood Hits	264	Target Neighborhood Hits	317	Shared Neighborhood Hits	122
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.098951 (rank : 231)
Query Neighborhood Hits	264	Target Neighborhood Hits	325	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.105933 (rank : 219)
Query Neighborhood Hits	264	Target Neighborhood Hits	287	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGF_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.069151 (rank : 352)
Query Neighborhood Hits	264	Target Neighborhood Hits	343	Shared Neighborhood Hits	113
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

ELTD1_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.051417 (rank : 399)
Query Neighborhood Hits	264	Target Neighborhood Hits	288	Shared Neighborhood Hits	87
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.070056 (rank : 349)
Query Neighborhood Hits	264	Target Neighborhood Hits	382	Shared Neighborhood Hits	109
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.068014 (rank : 357)
Query Neighborhood Hits	264	Target Neighborhood Hits	349	Shared Neighborhood Hits	103
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.068083 (rank : 356)
Query Neighborhood Hits	264	Target Neighborhood Hits	345	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

ESM1_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.054545 (rank : 389)
Query Neighborhood Hits	264	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FATH_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.050827 (rank : 401)
Query Neighborhood Hits	264	Target Neighborhood Hits	570	Shared Neighborhood Hits	126
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBLN1_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.096421 (rank : 247)
Query Neighborhood Hits	264	Target Neighborhood Hits	324	Shared Neighborhood Hits	118
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.097914 (rank : 235)
Query Neighborhood Hits	264	Target Neighborhood Hits	329	Shared Neighborhood Hits	121
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.091014 (rank : 274)
Query Neighborhood Hits	264	Target Neighborhood Hits	392	Shared Neighborhood Hits	120
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.093811 (rank : 257)
Query Neighborhood Hits	264	Target Neighborhood Hits	293	Shared Neighborhood Hits	109
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.099528 (rank : 230)
Query Neighborhood Hits	264	Target Neighborhood Hits	279	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.079498 (rank : 321)
Query Neighborhood Hits	264	Target Neighborhood Hits	278	Shared Neighborhood Hits	102
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.076422 (rank : 326)
Query Neighborhood Hits	264	Target Neighborhood Hits	270	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.081140 (rank : 315)
Query Neighborhood Hits	264	Target Neighborhood Hits	329	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.081391 (rank : 312)
Query Neighborhood Hits	264	Target Neighborhood Hits	317	Shared Neighborhood Hits	107
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

GAS6_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.084635 (rank : 300)
Query Neighborhood Hits	264	Target Neighborhood Hits	348	Shared Neighborhood Hits	119
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.080025 (rank : 319)
Query Neighborhood Hits	264	Target Neighborhood Hits	343	Shared Neighborhood Hits	126
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GRN_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.093349 (rank : 262)
Query Neighborhood Hits	264	Target Neighborhood Hits	248	Shared Neighborhood Hits	112
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HMCN1_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.121353 (rank : 193)
Query Neighborhood Hits	264	Target Neighborhood Hits	983	Shared Neighborhood Hits	153
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ITB1_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.084559 (rank : 301)
Query Neighborhood Hits	264	Target Neighborhood Hits	298	Shared Neighborhood Hits	134
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.081404 (rank : 311)
Query Neighborhood Hits	264	Target Neighborhood Hits	283	Shared Neighborhood Hits	126
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.080576 (rank : 318)
Query Neighborhood Hits	264	Target Neighborhood Hits	282	Shared Neighborhood Hits	123
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.103049 (rank : 224)
Query Neighborhood Hits	264	Target Neighborhood Hits	325	Shared Neighborhood Hits	150
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.104053 (rank : 222)
Query Neighborhood Hits	264	Target Neighborhood Hits	319	Shared Neighborhood Hits	142
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.090928 (rank : 275)
Query Neighborhood Hits	264	Target Neighborhood Hits	310	Shared Neighborhood Hits	135
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.111250 (rank : 209)
Query Neighborhood Hits	264	Target Neighborhood Hits	318	Shared Neighborhood Hits	153
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.115271 (rank : 201)
Query Neighborhood Hits	264	Target Neighborhood Hits	341	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.086385 (rank : 295)
Query Neighborhood Hits	264	Target Neighborhood Hits	290	Shared Neighborhood Hits	132
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.090296 (rank : 276)
Query Neighborhood Hits	264	Target Neighborhood Hits	277	Shared Neighborhood Hits	133
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.073310 (rank : 338)
Query Neighborhood Hits	264	Target Neighborhood Hits	280	Shared Neighborhood Hits	136
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.162281 (rank : 119)
Query Neighborhood Hits	264	Target Neighborhood Hits	261	Shared Neighborhood Hits	123
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.169380 (rank : 111)
Query Neighborhood Hits	264	Target Neighborhood Hits	264	Shared Neighborhood Hits	134
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.110920 (rank : 210)
Query Neighborhood Hits	264	Target Neighborhood Hits	212	Shared Neighborhood Hits	109
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR105_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.141660 (rank : 160)
Query Neighborhood Hits	264	Target Neighborhood Hits	271	Shared Neighborhood Hits	129
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR108_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.124878 (rank : 186)
Query Neighborhood Hits	264	Target Neighborhood Hits	226	Shared Neighborhood Hits	104
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.134984 (rank : 174)
Query Neighborhood Hits	264	Target Neighborhood Hits	226	Shared Neighborhood Hits	106
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.093098 (rank : 263)
Query Neighborhood Hits	264	Target Neighborhood Hits	232	Shared Neighborhood Hits	106
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR171_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.107627 (rank : 215)
Query Neighborhood Hits	264	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.089867 (rank : 279)
Query Neighborhood Hits	264	Target Neighborhood Hits	156	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.119888 (rank : 195)
Query Neighborhood Hits	264	Target Neighborhood Hits	178	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA11_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.112088 (rank : 208)
Query Neighborhood Hits	264	Target Neighborhood Hits	155	Shared Neighborhood Hits	88
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.098743 (rank : 233)
Query Neighborhood Hits	264	Target Neighborhood Hits	144	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.091341 (rank : 271)
Query Neighborhood Hits	264	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.066819 (rank : 359)
Query Neighborhood Hits	264	Target Neighborhood Hits	192	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.086542 (rank : 294)
Query Neighborhood Hits	264	Target Neighborhood Hits	149	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.093900 (rank : 256)
Query Neighborhood Hits	264	Target Neighborhood Hits	162	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA94_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.124402 (rank : 189)
Query Neighborhood Hits	264	Target Neighborhood Hits	204	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.136914 (rank : 171)
Query Neighborhood Hits	264	Target Neighborhood Hits	185	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.101002 (rank : 228)
Query Neighborhood Hits	264	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.090274 (rank : 277)
Query Neighborhood Hits	264	Target Neighborhood Hits	838	Shared Neighborhood Hits	147
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.075469 (rank : 330)
Query Neighborhood Hits	264	Target Neighborhood Hits	1092	Shared Neighborhood Hits	137
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.055268 (rank : 387)
Query Neighborhood Hits	264	Target Neighborhood Hits	760	Shared Neighborhood Hits	119
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.053261 (rank : 394)
Query Neighborhood Hits	264	Target Neighborhood Hits	708	Shared Neighborhood Hits	107
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.054486 (rank : 390)
Query Neighborhood Hits	264	Target Neighborhood Hits	584	Shared Neighborhood Hits	103
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.092037 (rank : 267)
Query Neighborhood Hits	264	Target Neighborhood Hits	1018	Shared Neighborhood Hits	150
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.084305 (rank : 302)
Query Neighborhood Hits	264	Target Neighborhood Hits	692	Shared Neighborhood Hits	140
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB3_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.074437 (rank : 333)
Query Neighborhood Hits	264	Target Neighborhood Hits	461	Shared Neighborhood Hits	119
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.075761 (rank : 328)
Query Neighborhood Hits	264	Target Neighborhood Hits	444	Shared Neighborhood Hits	123
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.087521 (rank : 291)
Query Neighborhood Hits	264	Target Neighborhood Hits	588	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.089429 (rank : 282)
Query Neighborhood Hits	264	Target Neighborhood Hits	624	Shared Neighborhood Hits	141
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.050751 (rank : 402)
Query Neighborhood Hits	264	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.068576 (rank : 354)
Query Neighborhood Hits	264	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.065894 (rank : 364)
Query Neighborhood Hits	264	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.072660 (rank : 341)
Query Neighborhood Hits	264	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.058974 (rank : 378)
Query Neighborhood Hits	264	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.056165 (rank : 386)
Query Neighborhood Hits	264	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE3A_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.073070 (rank : 339)
Query Neighborhood Hits	264	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LDLR_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.109601 (rank : 214)
Query Neighborhood Hits	264	Target Neighborhood Hits	375	Shared Neighborhood Hits	140
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.080892 (rank : 317)
Query Neighborhood Hits	264	Target Neighborhood Hits	382	Shared Neighborhood Hits	134
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP4_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.085940 (rank : 296)
Query Neighborhood Hits	264	Target Neighborhood Hits	355	Shared Neighborhood Hits	124
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.089874 (rank : 278)
Query Neighborhood Hits	264	Target Neighborhood Hits	351	Shared Neighborhood Hits	125
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.075625 (rank : 329)
Query Neighborhood Hits	264	Target Neighborhood Hits	346	Shared Neighborhood Hits	116
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTBP2_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.150322 (rank : 141)
Query Neighborhood Hits	264	Target Neighborhood Hits	552	Shared Neighborhood Hits	166
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.140608 (rank : 162)
Query Neighborhood Hits	264	Target Neighborhood Hits	617	Shared Neighborhood Hits	167
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MATN2_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.081282 (rank : 313)
Query Neighborhood Hits	264	Target Neighborhood Hits	365	Shared Neighborhood Hits	107
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.078683 (rank : 324)
Query Neighborhood Hits	264	Target Neighborhood Hits	356	Shared Neighborhood Hits	108
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.054259 (rank : 391)
Query Neighborhood Hits	264	Target Neighborhood Hits	268	Shared Neighborhood Hits	81
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.052776 (rank : 395)
Query Neighborhood Hits	264	Target Neighborhood Hits	261	Shared Neighborhood Hits	84
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.062232 (rank : 369)
Query Neighborhood Hits	264	Target Neighborhood Hits	287	Shared Neighborhood Hits	100
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.056253 (rank : 385)
Query Neighborhood Hits	264	Target Neighborhood Hits	277	Shared Neighborhood Hits	92
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCSP_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.093995 (rank : 255)
Query Neighborhood Hits	264	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEGF8_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.101893 (rank : 225)
Query Neighborhood Hits	264	Target Neighborhood Hits	528	Shared Neighborhood Hits	154
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.107547 (rank : 216)
Query Neighborhood Hits	264	Target Neighborhood Hits	520	Shared Neighborhood Hits	153
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MFGM_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.057039 (rank : 384)
Query Neighborhood Hits	264	Target Neighborhood Hits	233	Shared Neighborhood Hits	92
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MT1A_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.071538 (rank : 345)
Query Neighborhood Hits	264	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.140788 (rank : 161)
Query Neighborhood Hits	264	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1E_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.064323 (rank : 366)
Query Neighborhood Hits	264	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1F_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.059585 (rank : 375)
Query Neighborhood Hits	264	Target Neighborhood Hits	73	Shared Neighborhood Hits	25
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1H_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.081223 (rank : 314)
Query Neighborhood Hits	264	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1I_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.050425 (rank : 404)
Query Neighborhood Hits	264	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

MT1L_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.103289 (rank : 223)
Query Neighborhood Hits	264	Target Neighborhood Hits	73	Shared Neighborhood Hits	27
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1X_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.057475 (rank : 380)
Query Neighborhood Hits	264	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.097752 (rank : 237)
Query Neighborhood Hits	264	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.074216 (rank : 334)
Query Neighborhood Hits	264	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MT2_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.101360 (rank : 226)
Query Neighborhood Hits	264	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT4_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.083424 (rank : 304)
Query Neighborhood Hits	264	Target Neighborhood Hits	83	Shared Neighborhood Hits	37
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.088596 (rank : 283)
Query Neighborhood Hits	264	Target Neighborhood Hits	102	Shared Neighborhood Hits	50
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC5B_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.063646 (rank : 367)
Query Neighborhood Hits	264	Target Neighborhood Hits	1020	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NFX1_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.130214 (rank : 183)
Query Neighborhood Hits	264	Target Neighborhood Hits	405	Shared Neighborhood Hits	107
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.074649 (rank : 332)
Query Neighborhood Hits	264	Target Neighborhood Hits	329	Shared Neighborhood Hits	112
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.073652 (rank : 336)
Query Neighborhood Hits	264	Target Neighborhood Hits	335	Shared Neighborhood Hits	107
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.071616 (rank : 344)
Query Neighborhood Hits	264	Target Neighborhood Hits	456	Shared Neighborhood Hits	118
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.073793 (rank : 335)
Query Neighborhood Hits	264	Target Neighborhood Hits	338	Shared Neighborhood Hits	111
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NTNG1_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.073606 (rank : 337)
Query Neighborhood Hits	264	Target Neighborhood Hits	247	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.069081 (rank : 353)
Query Neighborhood Hits	264	Target Neighborhood Hits	246	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.081678 (rank : 309)
Query Neighborhood Hits	264	Target Neighborhood Hits	276	Shared Neighborhood Hits	117
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PGBM_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.066168 (rank : 361)
Query Neighborhood Hits	264	Target Neighborhood Hits	1113	Shared Neighborhood Hits	149
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.060566 (rank : 374)
Query Neighborhood Hits	264	Target Neighborhood Hits	1073	Shared Neighborhood Hits	144
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PROP_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.145406 (rank : 150)
Query Neighborhood Hits	264	Target Neighborhood Hits	126	Shared Neighborhood Hits	45
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.144308 (rank : 154)
Query Neighborhood Hits	264	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROS_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.089487 (rank : 281)
Query Neighborhood Hits	264	Target Neighborhood Hits	340	Shared Neighborhood Hits	123
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.081046 (rank : 316)
Query Neighborhood Hits	264	Target Neighborhood Hits	330	Shared Neighborhood Hits	118
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.052513 (rank : 396)
Query Neighborhood Hits	264	Target Neighborhood Hits	422	Shared Neighborhood Hits	106
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.051492 (rank : 398)
Query Neighborhood Hits	264	Target Neighborhood Hits	410	Shared Neighborhood Hits	102
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.083229 (rank : 305)
Query Neighborhood Hits	264	Target Neighborhood Hits	428	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.085907 (rank : 297)
Query Neighborhood Hits	264	Target Neighborhood Hits	442	Shared Neighborhood Hits	125
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEM5A_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.096573 (rank : 246)
Query Neighborhood Hits	264	Target Neighborhood Hits	177	Shared Neighborhood Hits	53
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.091643 (rank : 268)
Query Neighborhood Hits	264	Target Neighborhood Hits	162	Shared Neighborhood Hits	40
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.092196 (rank : 265)
Query Neighborhood Hits	264	Target Neighborhood Hits	178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5B_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.093750 (rank : 258)
Query Neighborhood Hits	264	Target Neighborhood Hits	190	Shared Neighborhood Hits	57
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SLIT2_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.085165 (rank : 299)
Query Neighborhood Hits	264	Target Neighborhood Hits	708	Shared Neighborhood Hits	147
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SORL_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.083165 (rank : 306)
Query Neighborhood Hits	264	Target Neighborhood Hits	440	Shared Neighborhood Hits	118
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.075108 (rank : 331)
Query Neighborhood Hits	264	Target Neighborhood Hits	439	Shared Neighborhood Hits	122
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPON1_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.132742 (rank : 178)
Query Neighborhood Hits	264	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.132548 (rank : 179)
Query Neighborhood Hits	264	Target Neighborhood Hits	123	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SUSD1_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.069497 (rank : 350)
Query Neighborhood Hits	264	Target Neighborhood Hits	285	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.051588 (rank : 397)
Query Neighborhood Hits	264	Target Neighborhood Hits	146	Shared Neighborhood Hits	79
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TEFF2_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.050611 (rank : 403)
Query Neighborhood Hits	264	Target Neighborhood Hits	214	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENN_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.107295 (rank : 217)
Query Neighborhood Hits	264	Target Neighborhood Hits	453	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.105432 (rank : 221)
Query Neighborhood Hits	264	Target Neighborhood Hits	526	Shared Neighborhood Hits	155
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.110687 (rank : 213)
Query Neighborhood Hits	264	Target Neighborhood Hits	531	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

THSD1_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.124473 (rank : 188)
Query Neighborhood Hits	264	Target Neighborhood Hits	136	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.114792 (rank : 202)
Query Neighborhood Hits	264	Target Neighborhood Hits	153	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TRBM_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.097352 (rank : 241)
Query Neighborhood Hits	264	Target Neighborhood Hits	361	Shared Neighborhood Hits	126
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.153813 (rank : 133)
Query Neighborhood Hits	264	Target Neighborhood Hits	389	Shared Neighborhood Hits	140
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.153458 (rank : 135)
Query Neighborhood Hits	264	Target Neighborhood Hits	396	Shared Neighborhood Hits	139
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.146216 (rank : 148)
Query Neighborhood Hits	264	Target Neighborhood Hits	359	Shared Neighborhood Hits	140
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.143672 (rank : 157)
Query Neighborhood Hits	264	Target Neighborhood Hits	352	Shared Neighborhood Hits	136
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.060649 (rank : 373)
Query Neighborhood Hits	264	Target Neighborhood Hits	250	Shared Neighborhood Hits	94
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.059186 (rank : 376)
Query Neighborhood Hits	264	Target Neighborhood Hits	247	Shared Neighborhood Hits	95
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.065366 (rank : 365)
Query Neighborhood Hits	264	Target Neighborhood Hits	277	Shared Neighborhood Hits	105
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.065912 (rank : 363)
Query Neighborhood Hits	264	Target Neighborhood Hits	276	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UNC5A_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.081523 (rank : 310)
Query Neighborhood Hits	264	Target Neighborhood Hits	198	Shared Neighborhood Hits	29
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.095238 (rank : 253)
Query Neighborhood Hits	264	Target Neighborhood Hits	203	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.091637 (rank : 269)
Query Neighborhood Hits	264	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.092288 (rank : 264)
Query Neighborhood Hits	264	Target Neighborhood Hits	226	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.088210 (rank : 287)
Query Neighborhood Hits	264	Target Neighborhood Hits	226	Shared Neighborhood Hits	32
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.088293 (rank : 285)
Query Neighborhood Hits	264	Target Neighborhood Hits	225	Shared Neighborhood Hits	32
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.086767 (rank : 292)
Query Neighborhood Hits	264	Target Neighborhood Hits	267	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.085804 (rank : 298)
Query Neighborhood Hits	264	Target Neighborhood Hits	268	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UROM_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.072200 (rank : 342)
Query Neighborhood Hits	264	Target Neighborhood Hits	284	Shared Neighborhood Hits	103
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.069320 (rank : 351)
Query Neighborhood Hits	264	Target Neighborhood Hits	276	Shared Neighborhood Hits	102
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.066107 (rank : 362)
Query Neighborhood Hits	264	Target Neighborhood Hits	600	Shared Neighborhood Hits	126
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.070412 (rank : 348)
Query Neighborhood Hits	264	Target Neighborhood Hits	626	Shared Neighborhood Hits	135
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VLDLR_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.092092 (rank : 266)
Query Neighborhood Hits	264	Target Neighborhood Hits	383	Shared Neighborhood Hits	137
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.096680 (rank : 245)
Query Neighborhood Hits	264	Target Neighborhood Hits	360	Shared Neighborhood Hits	133
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.058064 (rank : 379)
Query Neighborhood Hits	264	Target Neighborhood Hits	396	Shared Neighborhood Hits	123
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ZAN_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.050957 (rank : 400)
Query Neighborhood Hits	264	Target Neighborhood Hits	679	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

ADA33_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	264	Target Neighborhood Hits	264	Shared Neighborhood Hits	264
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
NC score	0.991185 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	264	Target Neighborhood Hits	231	Shared Neighborhood Hits	186
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA19_MOUSE
NC score	0.983579 (rank : 3)	θ value	1.0077e-184 (rank : 4)
Query Neighborhood Hits	264	Target Neighborhood Hits	315	Shared Neighborhood Hits	180
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA12_HUMAN
NC score	0.982856 (rank : 4)	θ value	1.56188e-169 (rank : 6)
Query Neighborhood Hits	264	Target Neighborhood Hits	224	Shared Neighborhood Hits	150
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA19_HUMAN
NC score	0.982065 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	264	Target Neighborhood Hits	381	Shared Neighborhood Hits	172
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA15_HUMAN
NC score	0.978033 (rank : 6)	θ value	1.98959e-140 (rank : 7)
Query Neighborhood Hits	264	Target Neighborhood Hits	288	Shared Neighborhood Hits	169
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA28_MOUSE
NC score	0.974604 (rank : 7)	θ value	1.06234e-117 (rank : 11)
Query Neighborhood Hits	264	Target Neighborhood Hits	241	Shared Neighborhood Hits	155
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADAM9_HUMAN
NC score	0.974426 (rank : 8)	θ value	1.69605e-115 (rank : 12)
Query Neighborhood Hits	264	Target Neighborhood Hits	243	Shared Neighborhood Hits	166
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM8_HUMAN
NC score	0.973567 (rank : 9)	θ value	2.13557e-126 (rank : 8)
Query Neighborhood Hits	264	Target Neighborhood Hits	327	Shared Neighborhood Hits	186
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
NC score	0.973072 (rank : 10)	θ value	1.13501e-119 (rank : 10)
Query Neighborhood Hits	264	Target Neighborhood Hits	326	Shared Neighborhood Hits	187
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADA28_HUMAN
NC score	0.972722 (rank : 11)	θ value	1.02895e-112 (rank : 14)
Query Neighborhood Hits	264	Target Neighborhood Hits	244	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADAM9_MOUSE
NC score	0.972598 (rank : 12)	θ value	4.1775e-114 (rank : 13)
Query Neighborhood Hits	264	Target Neighborhood Hits	325	Shared Neighborhood Hits	173
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA15_MOUSE
NC score	0.972567 (rank : 13)	θ value	1.38424e-125 (rank : 9)
Query Neighborhood Hits	264	Target Neighborhood Hits	324	Shared Neighborhood Hits	183
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA12_MOUSE
NC score	0.970112 (rank : 14)	θ value	6.34118e-171 (rank : 5)
Query Neighborhood Hits	264	Target Neighborhood Hits	474	Shared Neighborhood Hits	155
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM7_HUMAN
NC score	0.969884 (rank : 15)	θ value	1.54472e-92 (rank : 16)
Query Neighborhood Hits	264	Target Neighborhood Hits	221	Shared Neighborhood Hits	163
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
NC score	0.966154 (rank : 16)	θ value	2.91998e-83 (rank : 28)
Query Neighborhood Hits	264	Target Neighborhood Hits	200	Shared Neighborhood Hits	142
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADM1A_MOUSE
NC score	0.963000 (rank : 17)	θ value	1.35324e-88 (rank : 20)
Query Neighborhood Hits	264	Target Neighborhood Hits	230	Shared Neighborhood Hits	163
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA21_MOUSE
NC score	0.960515 (rank : 18)	θ value	1.2666e-86 (rank : 23)
Query Neighborhood Hits	264	Target Neighborhood Hits	172	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADM1B_MOUSE
NC score	0.959449 (rank : 19)	θ value	1.2268e-81 (rank : 30)
Query Neighborhood Hits	264	Target Neighborhood Hits	236	Shared Neighborhood Hits	145
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA22_HUMAN
NC score	0.958843 (rank : 20)	θ value	1.59853e-89 (rank : 19)
Query Neighborhood Hits	264	Target Neighborhood Hits	211	Shared Neighborhood Hits	140
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA23_MOUSE
NC score	0.958477 (rank : 21)	θ value	2.5521e-87 (rank : 22)
Query Neighborhood Hits	264	Target Neighborhood Hits	245	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_HUMAN
NC score	0.958309 (rank : 22)	θ value	1.2666e-86 (rank : 24)
Query Neighborhood Hits	264	Target Neighborhood Hits	235	Shared Neighborhood Hits	162
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA25_MOUSE
NC score	0.957959 (rank : 23)	θ value	3.68522e-86 (rank : 25)
Query Neighborhood Hits	264	Target Neighborhood Hits	213	Shared Neighborhood Hits	155
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA24_MOUSE
NC score	0.956372 (rank : 24)	θ value	3.0217e-80 (rank : 32)
Query Neighborhood Hits	264	Target Neighborhood Hits	230	Shared Neighborhood Hits	159
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA21_HUMAN
NC score	0.956067 (rank : 25)	θ value	9.37149e-90 (rank : 18)
Query Neighborhood Hits	264	Target Neighborhood Hits	181	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA11_MOUSE
NC score	0.955881 (rank : 26)	θ value	1.26366e-94 (rank : 15)
Query Neighborhood Hits	264	Target Neighborhood Hits	263	Shared Neighborhood Hits	176
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA22_MOUSE
NC score	0.955028 (rank : 27)	θ value	2.38869e-85 (rank : 27)
Query Neighborhood Hits	264	Target Neighborhood Hits	225	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

AD26A_MOUSE
NC score	0.954579 (rank : 28)	θ value	9.39325e-82 (rank : 29)
Query Neighborhood Hits	264	Target Neighborhood Hits	165	Shared Neighborhood Hits	135
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADEC1_HUMAN
NC score	0.952386 (rank : 29)	θ value	3.47335e-60 (rank : 39)
Query Neighborhood Hits	264	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA11_HUMAN
NC score	0.951751 (rank : 30)	θ value	5.86991e-92 (rank : 17)
Query Neighborhood Hits	264	Target Neighborhood Hits	259	Shared Neighborhood Hits	175
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA29_HUMAN
NC score	0.950489 (rank : 31)	θ value	1.26953e-78 (rank : 33)
Query Neighborhood Hits	264	Target Neighborhood Hits	247	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA32_HUMAN
NC score	0.948874 (rank : 32)	θ value	1.71583e-75 (rank : 34)
Query Neighborhood Hits	264	Target Neighborhood Hits	216	Shared Neighborhood Hits	156
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADAM2_MOUSE
NC score	0.948095 (rank : 33)	θ value	4.22625e-74 (rank : 37)
Query Neighborhood Hits	264	Target Neighborhood Hits	209	Shared Neighborhood Hits	149
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADA20_HUMAN
NC score	0.947974 (rank : 34)	θ value	2.30828e-88 (rank : 21)
Query Neighborhood Hits	264	Target Neighborhood Hits	143	Shared Neighborhood Hits	115
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA32_MOUSE
NC score	0.947180 (rank : 35)	θ value	7.20884e-74 (rank : 38)
Query Neighborhood Hits	264	Target Neighborhood Hits	219	Shared Neighborhood Hits	155
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADEC1_MOUSE
NC score	0.943650 (rank : 36)	θ value	4.25575e-50 (rank : 40)
Query Neighborhood Hits	264	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA18_MOUSE
NC score	0.942837 (rank : 37)	θ value	2.92676e-75 (rank : 35)
Query Neighborhood Hits	264	Target Neighborhood Hits	227	Shared Neighborhood Hits	158
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADAM2_HUMAN
NC score	0.939436 (rank : 38)	θ value	1.45253e-74 (rank : 36)
Query Neighborhood Hits	264	Target Neighborhood Hits	175	Shared Neighborhood Hits	132
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADA18_HUMAN
NC score	0.935280 (rank : 39)	θ value	3.0217e-80 (rank : 31)
Query Neighborhood Hits	264	Target Neighborhood Hits	184	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA30_HUMAN
NC score	0.934939 (rank : 40)	θ value	1.07224e-85 (rank : 26)
Query Neighborhood Hits	264	Target Neighborhood Hits	391	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA10_MOUSE
NC score	0.822389 (rank : 41)	θ value	8.08199e-25 (rank : 41)
Query Neighborhood Hits	264	Target Neighborhood Hits	194	Shared Neighborhood Hits	132
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA10_HUMAN
NC score	0.819372 (rank : 42)	θ value	3.07116e-24 (rank : 43)
Query Neighborhood Hits	264	Target Neighborhood Hits	189	Shared Neighborhood Hits	127
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA17_MOUSE
NC score	0.803318 (rank : 43)	θ value	8.36355e-22 (rank : 45)
Query Neighborhood Hits	264	Target Neighborhood Hits	201	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA17_HUMAN
NC score	0.801993 (rank : 44)	θ value	1.80048e-24 (rank : 42)
Query Neighborhood Hits	264	Target Neighborhood Hits	223	Shared Neighborhood Hits	130
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ATS7_HUMAN
NC score	0.612348 (rank : 45)	θ value	2.06002e-20 (rank : 50)
Query Neighborhood Hits	264	Target Neighborhood Hits	169	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS6_HUMAN
NC score	0.601020 (rank : 46)	θ value	2.0648e-12 (rank : 68)
Query Neighborhood Hits	264	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS20_HUMAN
NC score	0.593343 (rank : 47)	θ value	1.86321e-21 (rank : 48)
Query Neighborhood Hits	264	Target Neighborhood Hits	192	Shared Neighborhood Hits	99
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS5_MOUSE
NC score	0.588701 (rank : 48)	θ value	5.99374e-20 (rank : 53)
Query Neighborhood Hits	264	Target Neighborhood Hits	147	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS16_HUMAN
NC score	0.581059 (rank : 49)	θ value	6.40375e-22 (rank : 44)
Query Neighborhood Hits	264	Target Neighborhood Hits	208	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_MOUSE
NC score	0.578795 (rank : 50)	θ value	8.36355e-22 (rank : 47)
Query Neighborhood Hits	264	Target Neighborhood Hits	179	Shared Neighborhood Hits	90
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS12_HUMAN
NC score	0.576022 (rank : 51)	θ value	1.80466e-16 (rank : 58)
Query Neighborhood Hits	264	Target Neighborhood Hits	251	Shared Neighborhood Hits	84
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS5_HUMAN
NC score	0.575703 (rank : 52)	θ value	2.69047e-20 (rank : 51)
Query Neighborhood Hits	264	Target Neighborhood Hits	141	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS12_MOUSE
NC score	0.575627 (rank : 53)	θ value	1.29331e-14 (rank : 64)
Query Neighborhood Hits	264	Target Neighborhood Hits	220	Shared Neighborhood Hits	95
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS20_MOUSE
NC score	0.575329 (rank : 54)	θ value	4.15078e-21 (rank : 49)
Query Neighborhood Hits	264	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS18_HUMAN
NC score	0.570214 (rank : 55)	θ value	1.74391e-19 (rank : 55)
Query Neighborhood Hits	264	Target Neighborhood Hits	169	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS1_MOUSE
NC score	0.568839 (rank : 56)	θ value	5.07402e-19 (rank : 56)
Query Neighborhood Hits	264	Target Neighborhood Hits	158	Shared Neighborhood Hits	82
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS19_HUMAN
NC score	0.566097 (rank : 57)	θ value	7.58209e-15 (rank : 63)
Query Neighborhood Hits	264	Target Neighborhood Hits	203	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_MOUSE
NC score	0.564876 (rank : 58)	θ value	6.85773e-16 (rank : 60)
Query Neighborhood Hits	264	Target Neighborhood Hits	188	Shared Neighborhood Hits	85
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS3_HUMAN
NC score	0.563141 (rank : 59)	θ value	5.8054e-15 (rank : 62)
Query Neighborhood Hits	264	Target Neighborhood Hits	179	Shared Neighborhood Hits	86
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS9_HUMAN
NC score	0.563140 (rank : 60)	θ value	2.69047e-20 (rank : 52)
Query Neighborhood Hits	264	Target Neighborhood Hits	219	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS17_HUMAN
NC score	0.561655 (rank : 61)	θ value	7.84624e-12 (rank : 70)
Query Neighborhood Hits	264	Target Neighborhood Hits	194	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS14_HUMAN
NC score	0.556054 (rank : 62)	θ value	8.36355e-22 (rank : 46)
Query Neighborhood Hits	264	Target Neighborhood Hits	382	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS18_MOUSE
NC score	0.554243 (rank : 63)	θ value	6.85773e-16 (rank : 59)
Query Neighborhood Hits	264	Target Neighborhood Hits	163	Shared Neighborhood Hits	85
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS1_HUMAN
NC score	0.553286 (rank : 64)	θ value	1.24977e-17 (rank : 57)
Query Neighborhood Hits	264	Target Neighborhood Hits	159	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS15_HUMAN
NC score	0.550491 (rank : 65)	θ value	7.82807e-20 (rank : 54)
Query Neighborhood Hits	264	Target Neighborhood Hits	151	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS8_HUMAN
NC score	0.529357 (rank : 66)	θ value	1.29331e-14 (rank : 65)
Query Neighborhood Hits	264	Target Neighborhood Hits	145	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS2_HUMAN
NC score	0.524156 (rank : 67)	θ value	4.59992e-12 (rank : 69)
Query Neighborhood Hits	264	Target Neighborhood Hits	179	Shared Neighborhood Hits	86
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
NC score	0.521698 (rank : 68)	θ value	2.28291e-11 (rank : 71)
Query Neighborhood Hits	264	Target Neighborhood Hits	179	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS8_MOUSE
NC score	0.502367 (rank : 69)	θ value	4.44505e-15 (rank : 61)
Query Neighborhood Hits	264	Target Neighborhood Hits	139	Shared Neighborhood Hits	74
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS4_MOUSE
NC score	0.486344 (rank : 70)	θ value	1.2105e-12 (rank : 67)
Query Neighborhood Hits	264	Target Neighborhood Hits	145	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS4_HUMAN
NC score	0.477347 (rank : 71)	θ value	3.18553e-13 (rank : 66)
Query Neighborhood Hits	264	Target Neighborhood Hits	138	Shared Neighborhood Hits	77
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS13_MOUSE
NC score	0.395450 (rank : 72)	θ value	0.000121331 (rank : 79)
Query Neighborhood Hits	264	Target Neighborhood Hits	227	Shared Neighborhood Hits	88
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_HUMAN
NC score	0.395307 (rank : 73)	θ value	2.88788e-06 (rank : 75)
Query Neighborhood Hits	264	Target Neighborhood Hits	238	Shared Neighborhood Hits	79
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL5_HUMAN
NC score	0.279443 (rank : 74)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	264	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL1_HUMAN
NC score	0.269378 (rank : 75)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	264	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
NC score	0.268426 (rank : 76)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	264	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL2_HUMAN
NC score	0.253883 (rank : 77)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	264	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
NC score	0.253184 (rank : 78)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	264	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

KRA58_HUMAN
NC score	0.252476 (rank : 79)	θ value	0.813845 (rank : 164)
Query Neighborhood Hits	264	Target Neighborhood Hits	324	Shared Neighborhood Hits	145
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA53_HUMAN
NC score	0.249410 (rank : 80)	θ value	0.163984 (rank : 119)
Query Neighborhood Hits	264	Target Neighborhood Hits	331	Shared Neighborhood Hits	148
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
NC score	0.242042 (rank : 81)	θ value	0.0330416 (rank : 100)
Query Neighborhood Hits	264	Target Neighborhood Hits	270	Shared Neighborhood Hits	129
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA57_HUMAN
NC score	0.239301 (rank : 82)	θ value	3.0926 (rank : 207)
Query Neighborhood Hits	264	Target Neighborhood Hits	269	Shared Neighborhood Hits	133
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

ATL3_HUMAN
NC score	0.220328 (rank : 83)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	264	Target Neighborhood Hits	414	Shared Neighborhood Hits	56
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

KRA52_HUMAN
NC score	0.211488 (rank : 84)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	264	Target Neighborhood Hits	236	Shared Neighborhood Hits	115
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KR104_HUMAN
NC score	0.205238 (rank : 85)	θ value	0.21417 (rank : 123)
Query Neighborhood Hits	264	Target Neighborhood Hits	313	Shared Neighborhood Hits	138
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

NAGPA_MOUSE
NC score	0.203889 (rank : 86)	θ value	4.03905 (rank : 225)
Query Neighborhood Hits	264	Target Neighborhood Hits	308	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TENA_MOUSE
NC score	0.202893 (rank : 87)	θ value	0.00175202 (rank : 83)
Query Neighborhood Hits	264	Target Neighborhood Hits	596	Shared Neighborhood Hits	175
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

KRA51_HUMAN
NC score	0.202197 (rank : 88)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	264	Target Neighborhood Hits	288	Shared Neighborhood Hits	138
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

TENX_HUMAN
NC score	0.201982 (rank : 89)	θ value	8.97725e-08 (rank : 72)
Query Neighborhood Hits	264	Target Neighborhood Hits	789	Shared Neighborhood Hits	185
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

KR106_HUMAN
NC score	0.201856 (rank : 90)	θ value	0.21417 (rank : 124)
Query Neighborhood Hits	264	Target Neighborhood Hits	347	Shared Neighborhood Hits	157
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

SSPO_MOUSE
NC score	0.196726 (rank : 91)	θ value	0.365318 (rank : 145)
Query Neighborhood Hits	264	Target Neighborhood Hits	800	Shared Neighborhood Hits	196
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

WIF1_MOUSE
NC score	0.193571 (rank : 92)	θ value	0.0961366 (rank : 111)
Query Neighborhood Hits	264	Target Neighborhood Hits	393	Shared Neighborhood Hits	166
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

JAG2_HUMAN
NC score	0.190800 (rank : 93)	θ value	2.88788e-06 (rank : 76)
Query Neighborhood Hits	264	Target Neighborhood Hits	491	Shared Neighborhood Hits	173
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

TENA_HUMAN
NC score	0.190086 (rank : 94)	θ value	0.279714 (rank : 134)
Query Neighborhood Hits	264	Target Neighborhood Hits	631	Shared Neighborhood Hits	174
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

KR107_HUMAN
NC score	0.187975 (rank : 95)	θ value	0.279714 (rank : 130)
Query Neighborhood Hits	264	Target Neighborhood Hits	330	Shared Neighborhood Hits	146
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

JAG2_MOUSE
NC score	0.187337 (rank : 96)	θ value	0.813845 (rank : 163)
Query Neighborhood Hits	264	Target Neighborhood Hits	504	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

WIF1_HUMAN
NC score	0.185212 (rank : 97)	θ value	0.21417 (rank : 127)
Query Neighborhood Hits	264	Target Neighborhood Hits	392	Shared Neighborhood Hits	164
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

JAG1_HUMAN
NC score	0.185138 (rank : 98)	θ value	0.0330416 (rank : 99)
Query Neighborhood Hits	264	Target Neighborhood Hits	514	Shared Neighborhood Hits	177
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.183464 (rank : 99)	θ value	0.21417 (rank : 121)
Query Neighborhood Hits	264	Target Neighborhood Hits	518	Shared Neighborhood Hits	177
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KR510_HUMAN
NC score	0.182827 (rank : 100)	θ value	1.06291 (rank : 171)
Query Neighborhood Hits	264	Target Neighborhood Hits	217	Shared Neighborhood Hits	104
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

MEGF6_HUMAN
NC score	0.182571 (rank : 101)	θ value	1.69304e-06 (rank : 74)
Query Neighborhood Hits	264	Target Neighborhood Hits	671	Shared Neighborhood Hits	184
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KRA56_HUMAN
NC score	0.179405 (rank : 102)	θ value	0.47712 (rank : 149)
Query Neighborhood Hits	264	Target Neighborhood Hits	207	Shared Neighborhood Hits	101
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

DLL1_MOUSE
NC score	0.178903 (rank : 103)	θ value	0.21417 (rank : 120)
Query Neighborhood Hits	264	Target Neighborhood Hits	456	Shared Neighborhood Hits	169
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

NOTC1_HUMAN
NC score	0.178647 (rank : 104)	θ value	0.00869519 (rank : 90)
Query Neighborhood Hits	264	Target Neighborhood Hits	906	Shared Neighborhood Hits	181
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
NC score	0.178519 (rank : 105)	θ value	0.000158464 (rank : 80)
Query Neighborhood Hits	264	Target Neighborhood Hits	916	Shared Neighborhood Hits	178
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KRA59_HUMAN
NC score	0.177862 (rank : 106)	θ value	0.0961366 (rank : 109)
Query Neighborhood Hits	264	Target Neighborhood Hits	310	Shared Neighborhood Hits	120
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

NOTC2_HUMAN
NC score	0.177797 (rank : 107)	θ value	0.0330416 (rank : 101)
Query Neighborhood Hits	264	Target Neighborhood Hits	1113	Shared Neighborhood Hits	197
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
NC score	0.173228 (rank : 108)	θ value	0.125558 (rank : 115)
Query Neighborhood Hits	264	Target Neighborhood Hits	1069	Shared Neighborhood Hits	197
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SREC_HUMAN
NC score	0.170421 (rank : 109)	θ value	0.00298849 (rank : 84)
Query Neighborhood Hits	264	Target Neighborhood Hits	645	Shared Neighborhood Hits	176
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

DNER_HUMAN
NC score	0.169688 (rank : 110)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	264	Target Neighborhood Hits	460	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

KR102_HUMAN
NC score	0.169380 (rank : 111)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	264	Target Neighborhood Hits	264	Shared Neighborhood Hits	134
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR511_HUMAN
NC score	0.168386 (rank : 112)	θ value	0.47712 (rank : 148)
Query Neighborhood Hits	264	Target Neighborhood Hits	231	Shared Neighborhood Hits	98
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KR10C_HUMAN
NC score	0.168271 (rank : 113)	θ value	0.47712 (rank : 147)
Query Neighborhood Hits	264	Target Neighborhood Hits	219	Shared Neighborhood Hits	113
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

DLL1_HUMAN
NC score	0.167805 (rank : 114)	θ value	0.365318 (rank : 135)
Query Neighborhood Hits	264	Target Neighborhood Hits	455	Shared Neighborhood Hits	164
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

SREC2_MOUSE
NC score	0.167654 (rank : 115)	θ value	0.00869519 (rank : 91)
Query Neighborhood Hits	264	Target Neighborhood Hits	605	Shared Neighborhood Hits	168
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KRA55_HUMAN
NC score	0.166684 (rank : 116)	θ value	0.279714 (rank : 131)
Query Neighborhood Hits	264	Target Neighborhood Hits	257	Shared Neighborhood Hits	116
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

SREC2_HUMAN
NC score	0.166394 (rank : 117)	θ value	0.0252991 (rank : 97)
Query Neighborhood Hits	264	Target Neighborhood Hits	645	Shared Neighborhood Hits	168
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

NAGPA_HUMAN
NC score	0.163900 (rank : 118)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	264	Target Neighborhood Hits	282	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

KR101_HUMAN
NC score	0.162281 (rank : 119)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	264	Target Neighborhood Hits	261	Shared Neighborhood Hits	123
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

DNER_MOUSE
NC score	0.161003 (rank : 120)	θ value	2.36792 (rank : 196)
Query Neighborhood Hits	264	Target Neighborhood Hits	413	Shared Neighborhood Hits	152
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

NOTC3_MOUSE
NC score	0.160307 (rank : 121)	θ value	4.1701e-05 (rank : 78)
Query Neighborhood Hits	264	Target Neighborhood Hits	975	Shared Neighborhood Hits	183
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
NC score	0.160267 (rank : 122)	θ value	2.61198e-07 (rank : 73)
Query Neighborhood Hits	264	Target Neighborhood Hits	905	Shared Neighborhood Hits	178
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBN2_MOUSE
NC score	0.160050 (rank : 123)	θ value	0.00390308 (rank : 85)
Query Neighborhood Hits	264	Target Neighborhood Hits	549	Shared Neighborhood Hits	185
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.159594 (rank : 124)	θ value	0.0252991 (rank : 96)
Query Neighborhood Hits	264	Target Neighborhood Hits	563	Shared Neighborhood Hits	178
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

DLL3_MOUSE
NC score	0.159479 (rank : 125)	θ value	1.38821 (rank : 176)
Query Neighborhood Hits	264	Target Neighborhood Hits	399	Shared Neighborhood Hits	147
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_MOUSE
NC score	0.159364 (rank : 126)	θ value	0.0736092 (rank : 107)
Query Neighborhood Hits	264	Target Neighborhood Hits	440	Shared Neighborhood Hits	162
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC3_HUMAN
NC score	0.159358 (rank : 127)	θ value	0.000602161 (rank : 82)
Query Neighborhood Hits	264	Target Neighborhood Hits	1062	Shared Neighborhood Hits	185
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NELL2_HUMAN
NC score	0.158968 (rank : 128)	θ value	0.0431538 (rank : 104)
Query Neighborhood Hits	264	Target Neighborhood Hits	449	Shared Neighborhood Hits	158
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

FBN1_HUMAN
NC score	0.158157 (rank : 129)	θ value	0.0113563 (rank : 93)
Query Neighborhood Hits	264	Target Neighborhood Hits	557	Shared Neighborhood Hits	178
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

RELN_MOUSE
NC score	0.157595 (rank : 130)	θ value	0.813845 (rank : 170)
Query Neighborhood Hits	264	Target Neighborhood Hits	235	Shared Neighborhood Hits	120
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

CI094_HUMAN
NC score	0.155410 (rank : 131)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	264	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

FBN2_HUMAN
NC score	0.154339 (rank : 132)	θ value	0.00869519 (rank : 89)
Query Neighborhood Hits	264	Target Neighborhood Hits	560	Shared Neighborhood Hits	185
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

TSP1_HUMAN
NC score	0.153813 (rank : 133)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	264	Target Neighborhood Hits	389	Shared Neighborhood Hits	140
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

KRA93_HUMAN
NC score	0.153503 (rank : 134)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	264	Target Neighborhood Hits	203	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

TSP1_MOUSE
NC score	0.153458 (rank : 135)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	264	Target Neighborhood Hits	396	Shared Neighborhood Hits	139
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

KR10B_HUMAN
NC score	0.153069 (rank : 136)	θ value	2.36792 (rank : 200)
Query Neighborhood Hits	264	Target Neighborhood Hits	269	Shared Neighborhood Hits	124
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

ZAN_MOUSE
NC score	0.152648 (rank : 137)	θ value	1.38821 (rank : 188)
Query Neighborhood Hits	264	Target Neighborhood Hits	808	Shared Neighborhood Hits	182
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

HHIP_HUMAN
NC score	0.152576 (rank : 138)	θ value	0.62314 (rank : 156)
Query Neighborhood Hits	264	Target Neighborhood Hits	249	Shared Neighborhood Hits	145
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

DLL3_HUMAN
NC score	0.151987 (rank : 139)	θ value	0.0330416 (rank : 98)
Query Neighborhood Hits	264	Target Neighborhood Hits	419	Shared Neighborhood Hits	148
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

FBN3_HUMAN
NC score	0.151147 (rank : 140)	θ value	0.163984 (rank : 118)
Query Neighborhood Hits	264	Target Neighborhood Hits	543	Shared Neighborhood Hits	174
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LTBP2_HUMAN
NC score	0.150322 (rank : 141)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	264	Target Neighborhood Hits	552	Shared Neighborhood Hits	166
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NOTC4_MOUSE
NC score	0.149974 (rank : 142)	θ value	0.0563607 (rank : 106)
Query Neighborhood Hits	264	Target Neighborhood Hits	872	Shared Neighborhood Hits	179
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

RELN_HUMAN
NC score	0.149359 (rank : 143)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	264	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

NELL2_MOUSE
NC score	0.148004 (rank : 144)	θ value	0.0431538 (rank : 105)
Query Neighborhood Hits	264	Target Neighborhood Hits	436	Shared Neighborhood Hits	158
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

STAB2_HUMAN
NC score	0.147775 (rank : 145)	θ value	1.38821 (rank : 186)
Query Neighborhood Hits	264	Target Neighborhood Hits	534	Shared Neighborhood Hits	171
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LRP1B_HUMAN
NC score	0.147645 (rank : 146)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	264	Target Neighborhood Hits	602	Shared Neighborhood Hits	183
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

STAB1_MOUSE
NC score	0.147365 (rank : 147)	θ value	0.0330416 (rank : 102)
Query Neighborhood Hits	264	Target Neighborhood Hits	566	Shared Neighborhood Hits	171
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TSP2_HUMAN
NC score	0.146216 (rank : 148)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	264	Target Neighborhood Hits	359	Shared Neighborhood Hits	140
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

LRP1_HUMAN
NC score	0.145891 (rank : 149)	θ value	3.0926 (rank : 209)
Query Neighborhood Hits	264	Target Neighborhood Hits	617	Shared Neighborhood Hits	185
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

PROP_HUMAN
NC score	0.145406 (rank : 150)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	264	Target Neighborhood Hits	126	Shared Neighborhood Hits	45
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

STAB2_MOUSE
NC score	0.144674 (rank : 151)	θ value	0.365318 (rank : 146)
Query Neighborhood Hits	264	Target Neighborhood Hits	528	Shared Neighborhood Hits	174
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

DLL4_HUMAN
NC score	0.144510 (rank : 152)	θ value	0.62314 (rank : 153)
Query Neighborhood Hits	264	Target Neighborhood Hits	435	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

AGRIN_HUMAN
NC score	0.144475 (rank : 153)	θ value	0.163984 (rank : 116)
Query Neighborhood Hits	264	Target Neighborhood Hits	582	Shared Neighborhood Hits	168
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

PROP_MOUSE
NC score	0.144308 (rank : 154)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	264	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

CRUM2_HUMAN
NC score	0.144022 (rank : 155)	θ value	0.00869519 (rank : 88)
Query Neighborhood Hits	264	Target Neighborhood Hits	453	Shared Neighborhood Hits	152
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

LRP1B_MOUSE
NC score	0.143872 (rank : 156)	θ value	0.125558 (rank : 114)
Query Neighborhood Hits	264	Target Neighborhood Hits	606	Shared Neighborhood Hits	184
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TSP2_MOUSE
NC score	0.143672 (rank : 157)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	264	Target Neighborhood Hits	352	Shared Neighborhood Hits	136
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

C1QR1_HUMAN
NC score	0.143461 (rank : 158)	θ value	0.0113563 (rank : 92)
Query Neighborhood Hits	264	Target Neighborhood Hits	493	Shared Neighborhood Hits	142
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

DLK_HUMAN
NC score	0.143444 (rank : 159)	θ value	0.0431538 (rank : 103)
Query Neighborhood Hits	264	Target Neighborhood Hits	401	Shared Neighborhood Hits	163
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

KR105_HUMAN
NC score	0.141660 (rank : 160)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	264	Target Neighborhood Hits	271	Shared Neighborhood Hits	129
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

MT1B_HUMAN
NC score	0.140788 (rank : 161)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	264	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

LTBP2_MOUSE
NC score	0.140608 (rank : 162)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	264	Target Neighborhood Hits	617	Shared Neighborhood Hits	167
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTB1L_MOUSE
NC score	0.139948 (rank : 163)	θ value	0.813845 (rank : 167)
Query Neighborhood Hits	264	Target Neighborhood Hits	514	Shared Neighborhood Hits	165
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.139721 (rank : 164)	θ value	3.0926 (rank : 210)
Query Neighborhood Hits	264	Target Neighborhood Hits	502	Shared Neighborhood Hits	158
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.139509 (rank : 165)	θ value	0.813845 (rank : 168)
Query Neighborhood Hits	264	Target Neighborhood Hits	479	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_HUMAN
NC score	0.138866 (rank : 166)	θ value	0.62314 (rank : 159)
Query Neighborhood Hits	264	Target Neighborhood Hits	502	Shared Neighborhood Hits	162
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

DLK_MOUSE
NC score	0.138728 (rank : 167)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	264	Target Neighborhood Hits	374	Shared Neighborhood Hits	155
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

LTBP3_MOUSE
NC score	0.138140 (rank : 168)	θ value	0.365318 (rank : 143)
Query Neighborhood Hits	264	Target Neighborhood Hits	475	Shared Neighborhood Hits	167
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTB1L_HUMAN
NC score	0.137820 (rank : 169)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	264	Target Neighborhood Hits	553	Shared Neighborhood Hits	168
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

EGFL9_MOUSE
NC score	0.137190 (rank : 170)	θ value	0.365318 (rank : 138)
Query Neighborhood Hits	264	Target Neighborhood Hits	379	Shared Neighborhood Hits	148
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

KRA98_HUMAN
NC score	0.136914 (rank : 171)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	264	Target Neighborhood Hits	185	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

STAB1_HUMAN
NC score	0.136182 (rank : 172)	θ value	1.87187e-05 (rank : 77)
Query Neighborhood Hits	264	Target Neighborhood Hits	546	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

CRUM1_HUMAN
NC score	0.135874 (rank : 173)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	264	Target Neighborhood Hits	457	Shared Neighborhood Hits	157
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

KR109_HUMAN
NC score	0.134984 (rank : 174)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	264	Target Neighborhood Hits	226	Shared Neighborhood Hits	106
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

LTBP4_MOUSE
NC score	0.134966 (rank : 175)	θ value	0.0148317 (rank : 94)
Query Neighborhood Hits	264	Target Neighborhood Hits	607	Shared Neighborhood Hits	166
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

EGFL9_HUMAN
NC score	0.134028 (rank : 176)	θ value	0.365318 (rank : 137)
Query Neighborhood Hits	264	Target Neighborhood Hits	365	Shared Neighborhood Hits	146
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

HHIP_MOUSE
NC score	0.133335 (rank : 177)	θ value	0.365318 (rank : 140)
Query Neighborhood Hits	264	Target Neighborhood Hits	219	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

SPON1_HUMAN
NC score	0.132742 (rank : 178)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	264	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
NC score	0.132548 (rank : 179)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	264	Target Neighborhood Hits	123	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

FRAS1_HUMAN
NC score	0.132098 (rank : 180)	θ value	0.000602161 (rank : 81)
Query Neighborhood Hits	264	Target Neighborhood Hits	759	Shared Neighborhood Hits	166
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CRUM1_MOUSE
NC score	0.131508 (rank : 181)	θ value	0.163984 (rank : 117)
Query Neighborhood Hits	264	Target Neighborhood Hits	444	Shared Neighborhood Hits	150
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

EGFL8_MOUSE
NC score	0.131193 (rank : 182)	θ value	0.365318 (rank : 136)
Query Neighborhood Hits	264	Target Neighborhood Hits	266	Shared Neighborhood Hits	112
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

NFX1_HUMAN
NC score	0.130214 (rank : 183)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	264	Target Neighborhood Hits	405	Shared Neighborhood Hits	107
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NELL1_HUMAN
NC score	0.128483 (rank : 184)	θ value	0.47712 (rank : 150)
Query Neighborhood Hits	264	Target Neighborhood Hits	451	Shared Neighborhood Hits	153
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LRP2_HUMAN
NC score	0.127228 (rank : 185)	θ value	0.279714 (rank : 132)
Query Neighborhood Hits	264	Target Neighborhood Hits	573	Shared Neighborhood Hits	178
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

KR108_HUMAN
NC score	0.124878 (rank : 186)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	264	Target Neighborhood Hits	226	Shared Neighborhood Hits	104
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KRA47_HUMAN
NC score	0.124581 (rank : 187)	θ value	0.365318 (rank : 141)
Query Neighborhood Hits	264	Target Neighborhood Hits	204	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

THSD1_HUMAN
NC score	0.124473 (rank : 188)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	264	Target Neighborhood Hits	136	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

KRA94_HUMAN
NC score	0.124402 (rank : 189)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	264	Target Neighborhood Hits	204	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

FRAS1_MOUSE
NC score	0.123466 (rank : 190)	θ value	1.38821 (rank : 177)
Query Neighborhood Hits	264	Target Neighborhood Hits	747	Shared Neighborhood Hits	167
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KRA45_HUMAN
NC score	0.122358 (rank : 191)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	264	Target Neighborhood Hits	194	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

TENN_MOUSE
NC score	0.121965 (rank : 192)	θ value	2.36792 (rank : 205)
Query Neighborhood Hits	264	Target Neighborhood Hits	484	Shared Neighborhood Hits	161
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

HMCN1_HUMAN
NC score	0.121353 (rank : 193)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	264	Target Neighborhood Hits	983	Shared Neighborhood Hits	153
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CO8A_HUMAN
NC score	0.120198 (rank : 194)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	264	Target Neighborhood Hits	200	Shared Neighborhood Hits	82
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

KR412_HUMAN
NC score	0.119888 (rank : 195)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	264	Target Neighborhood Hits	178	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

ITB2_MOUSE
NC score	0.117742 (rank : 196)	θ value	2.36792 (rank : 199)
Query Neighborhood Hits	264	Target Neighborhood Hits	326	Shared Neighborhood Hits	154
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

CO6_HUMAN
NC score	0.117731 (rank : 197)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	264	Target Neighborhood Hits	331	Shared Neighborhood Hits	98
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

EGFL8_HUMAN
NC score	0.116624 (rank : 198)	θ value	0.813845 (rank : 161)
Query Neighborhood Hits	264	Target Neighborhood Hits	270	Shared Neighborhood Hits	111
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

MEGF9_HUMAN
NC score	0.115761 (rank : 199)	θ value	3.0926 (rank : 211)
Query Neighborhood Hits	264	Target Neighborhood Hits	557	Shared Neighborhood Hits	146
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KR414_HUMAN
NC score	0.115591 (rank : 200)	θ value	2.36792 (rank : 201)
Query Neighborhood Hits	264	Target Neighborhood Hits	199	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

ITB6_MOUSE
NC score	0.115271 (rank : 201)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	264	Target Neighborhood Hits	341	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

THSD1_MOUSE
NC score	0.114792 (rank : 202)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	264	Target Neighborhood Hits	153	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

PCSK5_MOUSE
NC score	0.114616 (rank : 203)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	264	Target Neighborhood Hits	613	Shared Neighborhood Hits	159
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CO8A_MOUSE
NC score	0.114416 (rank : 204)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	264	Target Neighborhood Hits	182	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CRIM1_HUMAN
NC score	0.113758 (rank : 205)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	264	Target Neighborhood Hits	362	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KRA92_HUMAN
NC score	0.113384 (rank : 206)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	264	Target Neighborhood Hits	198	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

CO8B_MOUSE
NC score	0.112253 (rank : 207)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	264	Target Neighborhood Hits	224	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

KRA11_HUMAN
NC score	0.112088 (rank : 208)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	264	Target Neighborhood Hits	155	Shared Neighborhood Hits	88
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

ITB6_HUMAN
NC score	0.111250 (rank : 209)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	264	Target Neighborhood Hits	318	Shared Neighborhood Hits	153
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KR103_HUMAN
NC score	0.110920 (rank : 210)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	264	Target Neighborhood Hits	212	Shared Neighborhood Hits	109
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

CO7_HUMAN
NC score	0.110883 (rank : 211)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	264	Target Neighborhood Hits	278	Shared Neighborhood Hits	90
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CREL1_HUMAN
NC score	0.110706 (rank : 212)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	264	Target Neighborhood Hits	441	Shared Neighborhood Hits	128
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

TENR_MOUSE
NC score	0.110687 (rank : 213)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	264	Target Neighborhood Hits	531	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

LDLR_HUMAN
NC score	0.109601 (rank : 214)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	264	Target Neighborhood Hits	375	Shared Neighborhood Hits	140
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KR171_HUMAN
NC score	0.107627 (rank : 215)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	264	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

MEGF8_MOUSE
NC score	0.107547 (rank : 216)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	264	Target Neighborhood Hits	520	Shared Neighborhood Hits	153
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TENN_HUMAN
NC score	0.107295 (rank : 217)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	264	Target Neighborhood Hits	453	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

FBLN2_MOUSE
NC score	0.106802 (rank : 218)	θ value	0.62314 (rank : 155)
Query Neighborhood Hits	264	Target Neighborhood Hits	505	Shared Neighborhood Hits	134
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

EGFL7_MOUSE
NC score	0.105933 (rank : 219)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	264	Target Neighborhood Hits	287	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

CUBN_MOUSE
NC score	0.105624 (rank : 220)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	264	Target Neighborhood Hits	477	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

TENR_HUMAN
NC score	0.105432 (rank : 221)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	264	Target Neighborhood Hits	526	Shared Neighborhood Hits	155
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB3_MOUSE
NC score	0.104053 (rank : 222)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	264	Target Neighborhood Hits	319	Shared Neighborhood Hits	142
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MT1L_HUMAN
NC score	0.103289 (rank : 223)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	264	Target Neighborhood Hits	73	Shared Neighborhood Hits	27
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

ITB3_HUMAN
NC score	0.103049 (rank : 224)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	264	Target Neighborhood Hits	325	Shared Neighborhood Hits	150
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MEGF8_HUMAN
NC score	0.101893 (rank : 225)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	264	Target Neighborhood Hits	528	Shared Neighborhood Hits	154
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MT2_MOUSE
NC score	0.101360 (rank : 226)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	264	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

TRBM_HUMAN
NC score	0.101079 (rank : 227)	θ value	0.00509761 (rank : 87)
Query Neighborhood Hits	264	Target Neighborhood Hits	339	Shared Neighborhood Hits	118
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KRA99_HUMAN
NC score	0.101002 (rank : 228)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	264	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

ITB5_MOUSE
NC score	0.100860 (rank : 229)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	264	Target Neighborhood Hits	329	Shared Neighborhood Hits	143
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

FBLN3_MOUSE
NC score	0.099528 (rank : 230)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	264	Target Neighborhood Hits	279	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

EGFL7_HUMAN
NC score	0.098951 (rank : 231)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	264	Target Neighborhood Hits	325	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

BAI1_HUMAN
NC score	0.098862 (rank : 232)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	264	Target Neighborhood Hits	375	Shared Neighborhood Hits	54
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

KRA13_HUMAN
NC score	0.098743 (rank : 233)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	264	Target Neighborhood Hits	144	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

CUBN_HUMAN
NC score	0.098603 (rank : 234)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	264	Target Neighborhood Hits	482	Shared Neighborhood Hits	144
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

FBLN1_MOUSE
NC score	0.097914 (rank : 235)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	264	Target Neighborhood Hits	329	Shared Neighborhood Hits	121
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

BAI1_MOUSE
NC score	0.097840 (rank : 236)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	264	Target Neighborhood Hits	340	Shared Neighborhood Hits	47
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

MT1_MOUSE
NC score	0.097752 (rank : 237)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	264	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

BAI3_MOUSE
NC score	0.097644 (rank : 238)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	264	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

NTNG2_MOUSE
NC score	0.097577 (rank : 239)	θ value	0.21417 (rank : 125)
Query Neighborhood Hits	264	Target Neighborhood Hits	276	Shared Neighborhood Hits	121
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

CREL1_MOUSE
NC score	0.097451 (rank : 240)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	264	Target Neighborhood Hits	524	Shared Neighborhood Hits	125
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

TRBM_MOUSE
NC score	0.097352 (rank : 241)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	264	Target Neighborhood Hits	361	Shared Neighborhood Hits	126
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LAMB2_MOUSE
NC score	0.097311 (rank : 242)	θ value	0.00390308 (rank : 86)
Query Neighborhood Hits	264	Target Neighborhood Hits	722	Shared Neighborhood Hits	141
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

GRN_HUMAN
NC score	0.096948 (rank : 243)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	264	Target Neighborhood Hits	268	Shared Neighborhood Hits	113
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

BAI2_HUMAN
NC score	0.096922 (rank : 244)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	264	Target Neighborhood Hits	332	Shared Neighborhood Hits	46
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

VLDLR_MOUSE
NC score	0.096680 (rank : 245)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	264	Target Neighborhood Hits	360	Shared Neighborhood Hits	133
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

SEM5A_HUMAN
NC score	0.096573 (rank : 246)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	264	Target Neighborhood Hits	177	Shared Neighborhood Hits	53
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

FBLN1_HUMAN
NC score	0.096421 (rank : 247)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	264	Target Neighborhood Hits	324	Shared Neighborhood Hits	118
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LAMA5_MOUSE
NC score	0.096328 (rank : 248)	θ value	0.62314 (rank : 158)
Query Neighborhood Hits	264	Target Neighborhood Hits	828	Shared Neighborhood Hits	150
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

BAI3_HUMAN
NC score	0.096196 (rank : 249)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	264	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

MEGF9_MOUSE
NC score	0.095711 (rank : 250)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	264	Target Neighborhood Hits	896	Shared Neighborhood Hits	143
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

BAI2_MOUSE
NC score	0.095463 (rank : 251)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	264	Target Neighborhood Hits	323	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

LAMA5_HUMAN
NC score	0.095293 (rank : 252)	θ value	3.0926 (rank : 208)
Query Neighborhood Hits	264	Target Neighborhood Hits	976	Shared Neighborhood Hits	162
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

UNC5A_MOUSE
NC score	0.095238 (rank : 253)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	264	Target Neighborhood Hits	203	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ITB4_HUMAN
NC score	0.094667 (rank : 254)	θ value	0.62314 (rank : 157)
Query Neighborhood Hits	264	Target Neighborhood Hits	458	Shared Neighborhood Hits	139
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

MCSP_MOUSE
NC score	0.093995 (rank : 255)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	264	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

KRA44_HUMAN
NC score	0.093900 (rank : 256)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	264	Target Neighborhood Hits	162	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

FBLN3_HUMAN
NC score	0.093811 (rank : 257)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	264	Target Neighborhood Hits	293	Shared Neighborhood Hits	109
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

SEM5B_MOUSE
NC score	0.093750 (rank : 258)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	264	Target Neighborhood Hits	190	Shared Neighborhood Hits	57
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

CO8B_HUMAN
NC score	0.093621 (rank : 259)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	264	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

LAMC2_HUMAN
NC score	0.093598 (rank : 260)	θ value	0.813845 (rank : 165)
Query Neighborhood Hits	264	Target Neighborhood Hits	715	Shared Neighborhood Hits	133
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMB1_MOUSE
NC score	0.093442 (rank : 261)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	264	Target Neighborhood Hits	919	Shared Neighborhood Hits	139
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

GRN_MOUSE
NC score	0.093349 (rank : 262)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	264	Target Neighborhood Hits	248	Shared Neighborhood Hits	112
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KR10A_HUMAN
NC score	0.093098 (rank : 263)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	264	Target Neighborhood Hits	232	Shared Neighborhood Hits	106
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

UNC5B_MOUSE
NC score	0.092288 (rank : 264)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	264	Target Neighborhood Hits	226	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

SEM5B_HUMAN
NC score	0.092196 (rank : 265)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	264	Target Neighborhood Hits	178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

VLDLR_HUMAN
NC score	0.092092 (rank : 266)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	264	Target Neighborhood Hits	383	Shared Neighborhood Hits	137
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LAMB1_HUMAN
NC score	0.092037 (rank : 267)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	264	Target Neighborhood Hits	1018	Shared Neighborhood Hits	150
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SEM5A_MOUSE
NC score	0.091643 (rank : 268)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	264	Target Neighborhood Hits	162	Shared Neighborhood Hits	40
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

UNC5B_HUMAN
NC score	0.091637 (rank : 269)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	264	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

SLIT1_HUMAN
NC score	0.091521 (rank : 270)	θ value	0.21417 (rank : 126)
Query Neighborhood Hits	264	Target Neighborhood Hits	700	Shared Neighborhood Hits	147
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

KRA15_HUMAN
NC score	0.091341 (rank : 271)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	264	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

CILP2_HUMAN
NC score	0.091135 (rank : 272)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	264	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

LAMC2_MOUSE
NC score	0.091058 (rank : 273)	θ value	0.0961366 (rank : 110)
Query Neighborhood Hits	264	Target Neighborhood Hits	614	Shared Neighborhood Hits	137
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

FBLN2_HUMAN
NC score	0.091014 (rank : 274)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	264	Target Neighborhood Hits	392	Shared Neighborhood Hits	120
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

ITB5_HUMAN
NC score	0.090928 (rank : 275)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	264	Target Neighborhood Hits	310	Shared Neighborhood Hits	135
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB7_MOUSE
NC score	0.090296 (rank : 276)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	264	Target Neighborhood Hits	277	Shared Neighborhood Hits	133
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LAMA1_MOUSE
NC score	0.090274 (rank : 277)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	264	Target Neighborhood Hits	838	Shared Neighborhood Hits	147
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LRP4_MOUSE
NC score	0.089874 (rank : 278)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	264	Target Neighborhood Hits	351	Shared Neighborhood Hits	125
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

KR410_HUMAN
NC score	0.089867 (rank : 279)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	264	Target Neighborhood Hits	156	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

C1QR1_MOUSE
NC score	0.089787 (rank : 280)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	264	Target Neighborhood Hits	342	Shared Neighborhood Hits	123
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

PROS_HUMAN
NC score	0.089487 (rank : 281)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	264	Target Neighborhood Hits	340	Shared Neighborhood Hits	123
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

LAMC3_MOUSE
NC score	0.089429 (rank : 282)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	264	Target Neighborhood Hits	624	Shared Neighborhood Hits	141
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MT4_MOUSE
NC score	0.088596 (rank : 283)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	264	Target Neighborhood Hits	102	Shared Neighborhood Hits	50
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

SLIT1_MOUSE
NC score	0.088539 (rank : 284)	θ value	0.47712 (rank : 151)
Query Neighborhood Hits	264	Target Neighborhood Hits	715	Shared Neighborhood Hits	149
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

UNC5C_MOUSE
NC score	0.088293 (rank : 285)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	264	Target Neighborhood Hits	225	Shared Neighborhood Hits	32
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

LAMA1_HUMAN
NC score	0.088285 (rank : 286)	θ value	0.0193708 (rank : 95)
Query Neighborhood Hits	264	Target Neighborhood Hits	804	Shared Neighborhood Hits	144
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

UNC5C_HUMAN
NC score	0.088210 (rank : 287)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	264	Target Neighborhood Hits	226	Shared Neighborhood Hits	32
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

SLIT3_MOUSE
NC score	0.088061 (rank : 288)	θ value	0.279714 (rank : 133)
Query Neighborhood Hits	264	Target Neighborhood Hits	700	Shared Neighborhood Hits	148
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

LAMA3_MOUSE
NC score	0.087982 (rank : 289)	θ value	0.365318 (rank : 142)
Query Neighborhood Hits	264	Target Neighborhood Hits	859	Shared Neighborhood Hits	156
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

SLIT2_MOUSE
NC score	0.087593 (rank : 290)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	264	Target Neighborhood Hits	684	Shared Neighborhood Hits	142
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LAMC3_HUMAN
NC score	0.087521 (rank : 291)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	264	Target Neighborhood Hits	588	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

UNC5D_HUMAN
NC score	0.086767 (rank : 292)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	264	Target Neighborhood Hits	267	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

LRP8_MOUSE
NC score	0.086640 (rank : 293)	θ value	0.813845 (rank : 166)
Query Neighborhood Hits	264	Target Neighborhood Hits	385	Shared Neighborhood Hits	124
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

KRA42_HUMAN
NC score	0.086542 (rank : 294)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	264	Target Neighborhood Hits	149	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

ITB7_HUMAN
NC score	0.086385 (rank : 295)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	264	Target Neighborhood Hits	290	Shared Neighborhood Hits	132
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LRP4_HUMAN
NC score	0.085940 (rank : 296)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	264	Target Neighborhood Hits	355	Shared Neighborhood Hits	124
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

SCUB3_MOUSE
NC score	0.085907 (rank : 297)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	264	Target Neighborhood Hits	442	Shared Neighborhood Hits	125
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

UNC5D_MOUSE
NC score	0.085804 (rank : 298)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	264	Target Neighborhood Hits	268	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

SLIT2_HUMAN
NC score	0.085165 (rank : 299)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	264	Target Neighborhood Hits	708	Shared Neighborhood Hits	147
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

GAS6_HUMAN
NC score	0.084635 (rank : 300)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	264	Target Neighborhood Hits	348	Shared Neighborhood Hits	119
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITB1_HUMAN
NC score	0.084559 (rank : 301)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	264	Target Neighborhood Hits	298	Shared Neighborhood Hits	134
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

LAMB2_HUMAN
NC score	0.084305 (rank : 302)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	264	Target Neighborhood Hits	692	Shared Neighborhood Hits	140
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

EDIL3_MOUSE
NC score	0.083635 (rank : 303)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	264	Target Neighborhood Hits	317	Shared Neighborhood Hits	122
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MT4_HUMAN
NC score	0.083424 (rank : 304)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	264	Target Neighborhood Hits	83	Shared Neighborhood Hits	37
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

SCUB3_HUMAN
NC score	0.083229 (rank : 305)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	264	Target Neighborhood Hits	428	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SORL_HUMAN
NC score	0.083165 (rank : 306)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	264	Target Neighborhood Hits	440	Shared Neighborhood Hits	118
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SLIT3_HUMAN
NC score	0.083116 (rank : 307)	θ value	0.62314 (rank : 160)
Query Neighborhood Hits	264	Target Neighborhood Hits	682	Shared Neighborhood Hits	139
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

LAMC1_MOUSE
NC score	0.081741 (rank : 308)	θ value	1.81305 (rank : 193)
Query Neighborhood Hits	264	Target Neighborhood Hits	856	Shared Neighborhood Hits	138
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NTNG2_HUMAN
NC score	0.081678 (rank : 309)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	264	Target Neighborhood Hits	276	Shared Neighborhood Hits	117
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

UNC5A_HUMAN
NC score	0.081523 (rank : 310)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	264	Target Neighborhood Hits	198	Shared Neighborhood Hits	29
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ITB1_MOUSE
NC score	0.081404 (rank : 311)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	264	Target Neighborhood Hits	283	Shared Neighborhood Hits	126
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

FBLN5_MOUSE
NC score	0.081391 (rank : 312)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	264	Target Neighborhood Hits	317	Shared Neighborhood Hits	107
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

MATN2_HUMAN
NC score	0.081282 (rank : 313)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	264	Target Neighborhood Hits	365	Shared Neighborhood Hits	107
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MT1H_HUMAN
NC score	0.081223 (rank : 314)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	264	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

FBLN5_HUMAN
NC score	0.081140 (rank : 315)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	264	Target Neighborhood Hits	329	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

PROS_MOUSE
NC score	0.081046 (rank : 316)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	264	Target Neighborhood Hits	330	Shared Neighborhood Hits	118
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

LDLR_MOUSE
NC score	0.080892 (rank : 317)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	264	Target Neighborhood Hits	382	Shared Neighborhood Hits	134
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

ITB2_HUMAN
NC score	0.080576 (rank : 318)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	264	Target Neighborhood Hits	282	Shared Neighborhood Hits	123
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

GAS6_MOUSE
NC score	0.080025 (rank : 319)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	264	Target Neighborhood Hits	343	Shared Neighborhood Hits	126
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

EGF_MOUSE
NC score	0.080020 (rank : 320)	θ value	0.365318 (rank : 139)
Query Neighborhood Hits	264	Target Neighborhood Hits	358	Shared Neighborhood Hits	119
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FBLN4_HUMAN
NC score	0.079498 (rank : 321)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	264	Target Neighborhood Hits	278	Shared Neighborhood Hits	102
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

EDIL3_HUMAN
NC score	0.079190 (rank : 322)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	264	Target Neighborhood Hits	292	Shared Neighborhood Hits	114
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LAMC1_HUMAN
NC score	0.078966 (rank : 323)	θ value	1.81305 (rank : 192)
Query Neighborhood Hits	264	Target Neighborhood Hits	922	Shared Neighborhood Hits	139
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MATN2_MOUSE
NC score	0.078683 (rank : 324)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	264	Target Neighborhood Hits	356	Shared Neighborhood Hits	108
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

LAMA2_MOUSE
NC score	0.077339 (rank : 325)	θ value	1.81305 (rank : 191)
Query Neighborhood Hits	264	Target Neighborhood Hits	1198	Shared Neighborhood Hits	152
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

FBLN4_MOUSE
NC score	0.076422 (rank : 326)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	264	Target Neighborhood Hits	270	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

ATRN_MOUSE
NC score	0.076138 (rank : 327)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	264	Target Neighborhood Hits	519	Shared Neighborhood Hits	140
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

LAMB3_MOUSE
NC score	0.075761 (rank : 328)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	264	Target Neighborhood Hits	444	Shared Neighborhood Hits	123
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LRP8_HUMAN
NC score	0.075625 (rank : 329)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	264	Target Neighborhood Hits	346	Shared Neighborhood Hits	116
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LAMA2_HUMAN
NC score	0.075469 (rank : 330)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	264	Target Neighborhood Hits	1092	Shared Neighborhood Hits	137
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SORL_MOUSE
NC score	0.075108 (rank : 331)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	264	Target Neighborhood Hits	439	Shared Neighborhood Hits	122
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

NID1_HUMAN
NC score	0.074649 (rank : 332)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	264	Target Neighborhood Hits	329	Shared Neighborhood Hits	112
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LAMB3_HUMAN
NC score	0.074437 (rank : 333)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	264	Target Neighborhood Hits	461	Shared Neighborhood Hits	119
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

MT2_HUMAN
NC score	0.074216 (rank : 334)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	264	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

NID2_MOUSE
NC score	0.073793 (rank : 335)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	264	Target Neighborhood Hits	338	Shared Neighborhood Hits	111
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID1_MOUSE
NC score	0.073652 (rank : 336)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	264	Target Neighborhood Hits	335	Shared Neighborhood Hits	107
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NTNG1_HUMAN
NC score	0.073606 (rank : 337)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	264	Target Neighborhood Hits	247	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ITB8_HUMAN
NC score	0.073310 (rank : 338)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	264	Target Neighborhood Hits	280	Shared Neighborhood Hits	136
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

LCE3A_HUMAN
NC score	0.073070 (rank : 339)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	264	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

CD97_MOUSE
NC score	0.072711 (rank : 340)	θ value	0.125558 (rank : 112)
Query Neighborhood Hits	264	Target Neighborhood Hits	295	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

LCE1D_HUMAN
NC score	0.072660 (rank : 341)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	264	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

UROM_HUMAN
NC score	0.072200 (rank : 342)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	264	Target Neighborhood Hits	284	Shared Neighborhood Hits	103
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

COMP_HUMAN
NC score	0.072108 (rank : 343)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	264	Target Neighborhood Hits	258	Shared Neighborhood Hits	113
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NID2_HUMAN
NC score	0.071616 (rank : 344)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	264	Target Neighborhood Hits	456	Shared Neighborhood Hits	118
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

MT1A_HUMAN
NC score	0.071538 (rank : 345)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	264	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

COMP_MOUSE
NC score	0.071166 (rank : 346)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	264	Target Neighborhood Hits	290	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CSPG2_MOUSE
NC score	0.070707 (rank : 347)	θ value	0.125558 (rank : 113)
Query Neighborhood Hits	264	Target Neighborhood Hits	711	Shared Neighborhood Hits	115
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

USH2A_MOUSE
NC score	0.070412 (rank : 348)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	264	Target Neighborhood Hits	626	Shared Neighborhood Hits	135
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

EMR1_HUMAN
NC score	0.070056 (rank : 349)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	264	Target Neighborhood Hits	382	Shared Neighborhood Hits	109
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

SUSD1_HUMAN
NC score	0.069497 (rank : 350)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	264	Target Neighborhood Hits	285	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

UROM_MOUSE
NC score	0.069320 (rank : 351)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	264	Target Neighborhood Hits	276	Shared Neighborhood Hits	102
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

EGF_HUMAN
NC score	0.069151 (rank : 352)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	264	Target Neighborhood Hits	343	Shared Neighborhood Hits	113
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

NTNG1_MOUSE
NC score	0.069081 (rank : 353)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	264	Target Neighborhood Hits	246	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LCE1B_HUMAN
NC score	0.068576 (rank : 354)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	264	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

CSPG2_HUMAN
NC score	0.068481 (rank : 355)	θ value	0.279714 (rank : 128)
Query Neighborhood Hits	264	Target Neighborhood Hits	681	Shared Neighborhood Hits	115
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

EMR2_HUMAN
NC score	0.068083 (rank : 356)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	264	Target Neighborhood Hits	345	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR1_MOUSE
NC score	0.068014 (rank : 357)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	264	Target Neighborhood Hits	349	Shared Neighborhood Hits	103
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

ATRN_HUMAN
NC score	0.067848 (rank : 358)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	264	Target Neighborhood Hits	525	Shared Neighborhood Hits	138
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

KRA24_HUMAN
NC score	0.066819 (rank : 359)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	264	Target Neighborhood Hits	192	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

CD97_HUMAN
NC score	0.066502 (rank : 360)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	264	Target Neighborhood Hits	353	Shared Neighborhood Hits	104
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

PGBM_HUMAN
NC score	0.066168 (rank : 361)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	264	Target Neighborhood Hits	1113	Shared Neighborhood Hits	149
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

USH2A_HUMAN
NC score	0.066107 (rank : 362)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	264	Target Neighborhood Hits	600	Shared Neighborhood Hits	126
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

TSP4_MOUSE
NC score	0.065912 (rank : 363)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	264	Target Neighborhood Hits	276	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

LCE1C_HUMAN
NC score	0.065894 (rank : 364)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	264	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

TSP4_HUMAN
NC score	0.065366 (rank : 365)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	264	Target Neighborhood Hits	277	Shared Neighborhood Hits	105
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

MT1E_HUMAN
NC score	0.064323 (rank : 366)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	264	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MUC5B_HUMAN
NC score	0.063646 (rank : 367)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	264	Target Neighborhood Hits	1020	Shared Neighborhood Hits	141
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CD248_HUMAN
NC score	0.063572 (rank : 368)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	264	Target Neighborhood Hits	679	Shared Neighborhood Hits	114
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MATN4_HUMAN
NC score	0.062232 (rank : 369)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	264	Target Neighborhood Hits	287	Shared Neighborhood Hits	100
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

CILP1_HUMAN
NC score	0.061801 (rank : 370)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	264	Target Neighborhood Hits	266	Shared Neighborhood Hits	36
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

LYAM2_MOUSE
NC score	0.061700 (rank : 371)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	264	Target Neighborhood Hits	420	Shared Neighborhood Hits	128
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CD248_MOUSE
NC score	0.061034 (rank : 372)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	264	Target Neighborhood Hits	578	Shared Neighborhood Hits	103
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TSP3_HUMAN
NC score	0.060649 (rank : 373)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	264	Target Neighborhood Hits	250	Shared Neighborhood Hits	94
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

PGBM_MOUSE
NC score	0.060566 (rank : 374)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	264	Target Neighborhood Hits	1073	Shared Neighborhood Hits	144
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MT1F_HUMAN
NC score	0.059585 (rank : 375)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	264	Target Neighborhood Hits	73	Shared Neighborhood Hits	25
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

TSP3_MOUSE
NC score	0.059186 (rank : 376)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	264	Target Neighborhood Hits	247	Shared Neighborhood Hits	95
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

CILP1_MOUSE
NC score	0.059091 (rank : 377)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	264	Target Neighborhood Hits	282	Shared Neighborhood Hits	36
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

LCE1E_HUMAN
NC score	0.058974 (rank : 378)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	264	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

VWF_HUMAN
NC score	0.058064 (rank : 379)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	264	Target Neighborhood Hits	396	Shared Neighborhood Hits	123
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MT1X_HUMAN
NC score	0.057475 (rank : 380)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	264	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

CSPG3_HUMAN
NC score	0.057339 (rank : 381)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	264	Target Neighborhood Hits	676	Shared Neighborhood Hits	119
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
NC score	0.057215 (rank : 382)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	264	Target Neighborhood Hits	657	Shared Neighborhood Hits	116
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CFC1_HUMAN
NC score	0.057187 (rank : 383)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	264	Target Neighborhood Hits	148	Shared Neighborhood Hits	83
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

MFGM_MOUSE
NC score	0.057039 (rank : 384)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	264	Target Neighborhood Hits	233	Shared Neighborhood Hits	92
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MATN4_MOUSE
NC score	0.056253 (rank : 385)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	264	Target Neighborhood Hits	277	Shared Neighborhood Hits	92
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

LCE1F_HUMAN
NC score	0.056165 (rank : 386)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	264	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LAMA3_HUMAN
NC score	0.055268 (rank : 387)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	264	Target Neighborhood Hits	760	Shared Neighborhood Hits	119
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

CT127_HUMAN
NC score	0.055012 (rank : 388)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	264	Target Neighborhood Hits	67	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

ESM1_HUMAN
NC score	0.054545 (rank : 389)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	264	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

LAMA4_MOUSE
NC score	0.054486 (rank : 390)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	264	Target Neighborhood Hits	584	Shared Neighborhood Hits	103
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MATN3_HUMAN
NC score	0.054259 (rank : 391)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	264	Target Neighborhood Hits	268	Shared Neighborhood Hits	81
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

CYR61_HUMAN
NC score	0.053382 (rank : 392)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	264	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CFC1_MOUSE
NC score	0.053358 (rank : 393)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	264	Target Neighborhood Hits	125	Shared Neighborhood Hits	74
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

LAMA4_HUMAN
NC score	0.053261 (rank : 394)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	264	Target Neighborhood Hits	708	Shared Neighborhood Hits	107
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MATN3_MOUSE
NC score	0.052776 (rank : 395)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	264	Target Neighborhood Hits	261	Shared Neighborhood Hits	84
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

PROZ_HUMAN
NC score	0.052513 (rank : 396)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	264	Target Neighborhood Hits	422	Shared Neighborhood Hits	106
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TDGF1_MOUSE
NC score	0.051588 (rank : 397)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	264	Target Neighborhood Hits	146	Shared Neighborhood Hits	79
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

PROZ_MOUSE
NC score	0.051492 (rank : 398)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	264	Target Neighborhood Hits	410	Shared Neighborhood Hits	102
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

ELTD1_MOUSE
NC score	0.051417 (rank : 399)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	264	Target Neighborhood Hits	288	Shared Neighborhood Hits	87
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ZAN_HUMAN
NC score	0.050957 (rank : 400)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	264	Target Neighborhood Hits	679	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

FATH_HUMAN
NC score	0.050827 (rank : 401)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	264	Target Neighborhood Hits	570	Shared Neighborhood Hits	126
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

LCE1A_HUMAN
NC score	0.050751 (rank : 402)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	264	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

TEFF2_MOUSE
NC score	0.050611 (rank : 403)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	264	Target Neighborhood Hits	214	Shared Neighborhood Hits	86
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

MT1I_HUMAN
NC score	0.050425 (rank : 404)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	264	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

NET4_MOUSE
NC score	0.050185 (rank : 405)	θ value	2.36792 (rank : 202)
Query Neighborhood Hits	264	Target Neighborhood Hits	180	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

CELR3_HUMAN
NC score	0.044918 (rank : 406)	θ value	0.62314 (rank : 152)
Query Neighborhood Hits	264	Target Neighborhood Hits	680	Shared Neighborhood Hits	140
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

TIE1_HUMAN
NC score	0.039351 (rank : 407)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	264	Target Neighborhood Hits	1241	Shared Neighborhood Hits	141
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
NC score	0.039002 (rank : 408)	θ value	2.36792 (rank : 206)
Query Neighborhood Hits	264	Target Neighborhood Hits	1266	Shared Neighborhood Hits	142
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

OC90_MOUSE
NC score	0.036432 (rank : 409)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	264	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0L3, Q9CZ60, Q9Z225	Gene names	Oc90, Onc-95, Pla2ll
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Otoconin-95) (Oc95).

FA12_HUMAN
NC score	0.032813 (rank : 410)	θ value	0.62314 (rank : 154)
Query Neighborhood Hits	264	Target Neighborhood Hits	425	Shared Neighborhood Hits	96
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

LCE5A_HUMAN
NC score	0.032753 (rank : 411)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	264	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

DKK4_HUMAN
NC score	0.029873 (rank : 412)	θ value	0.279714 (rank : 129)
Query Neighborhood Hits	264	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBT3, Q9Y4C3	Gene names	DKK4
Domain Architecture
Description	Dickkopf-related protein 4 precursor (Dkk-4) (Dickkopf-4) (hDkk-4) [Contains: Dickkopf-related protein 4 short form].

HYAL3_MOUSE
NC score	0.028947 (rank : 413)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	264	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

COLQ_HUMAN
NC score	0.027911 (rank : 414)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	264	Target Neighborhood Hits	193	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

PAPPA_HUMAN
NC score	0.026836 (rank : 415)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	264	Target Neighborhood Hits	161	Shared Neighborhood Hits	45
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PROC_HUMAN
NC score	0.025832 (rank : 416)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	264	Target Neighborhood Hits	406	Shared Neighborhood Hits	101
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PS1C2_MOUSE
NC score	0.025369 (rank : 417)	θ value	3.0926 (rank : 215)
Query Neighborhood Hits	264	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

TIE2_HUMAN
NC score	0.025312 (rank : 418)	θ value	3.0926 (rank : 217)
Query Neighborhood Hits	264	Target Neighborhood Hits	1192	Shared Neighborhood Hits	125
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

PAPPA_MOUSE
NC score	0.023376 (rank : 419)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	264	Target Neighborhood Hits	153	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

MMP7_MOUSE
NC score	0.022472 (rank : 420)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	264	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

PS1C2_HUMAN
NC score	0.021465 (rank : 421)	θ value	3.0926 (rank : 214)
Query Neighborhood Hits	264	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

SF01_HUMAN
NC score	0.019088 (rank : 422)	θ value	1.06291 (rank : 174)
Query Neighborhood Hits	264	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF3A2_HUMAN
NC score	0.017258 (rank : 423)	θ value	1.38821 (rank : 185)
Query Neighborhood Hits	264	Target Neighborhood Hits	263	Shared Neighborhood Hits	14
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

GGN_MOUSE
NC score	0.015061 (rank : 424)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	264	Target Neighborhood Hits	311	Shared Neighborhood Hits	12
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SPR2F_MOUSE
NC score	0.014505 (rank : 425)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	264	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

MMP1B_MOUSE
NC score	0.014162 (rank : 426)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	264	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

PRP1_HUMAN
NC score	0.013666 (rank : 427)	θ value	0.813845 (rank : 169)
Query Neighborhood Hits	264	Target Neighborhood Hits	385	Shared Neighborhood Hits	11
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SF01_MOUSE
NC score	0.013402 (rank : 428)	θ value	1.06291 (rank : 175)
Query Neighborhood Hits	264	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

MMP7_HUMAN
NC score	0.013267 (rank : 429)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	264	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P09237, Q9BTK9	Gene names	MMP7, MPSL1, PUMP1
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

RN167_MOUSE
NC score	0.013237 (rank : 430)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	264	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

SPN90_MOUSE
NC score	0.012666 (rank : 431)	θ value	0.365318 (rank : 144)
Query Neighborhood Hits	264	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

MMP1A_MOUSE
NC score	0.012412 (rank : 432)	θ value	3.0926 (rank : 212)
Query Neighborhood Hits	264	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

SF3A2_MOUSE
NC score	0.012238 (rank : 433)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	264	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

RN167_HUMAN
NC score	0.011823 (rank : 434)	θ value	1.06291 (rank : 173)
Query Neighborhood Hits	264	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

PRG4_HUMAN
NC score	0.010436 (rank : 435)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	264	Target Neighborhood Hits	764	Shared Neighborhood Hits	35
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MMP28_HUMAN
NC score	0.009751 (rank : 436)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	264	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H239, Q96TE2	Gene names	MMP28, MMP25
Domain Architecture
Description	Matrix metalloproteinase-28 precursor (EC 3.4.24.-) (MMP-28) (Epilysin).

K1802_MOUSE
NC score	0.009023 (rank : 437)	θ value	0.21417 (rank : 122)
Query Neighborhood Hits	264	Target Neighborhood Hits	1596	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MMP1_HUMAN
NC score	0.008491 (rank : 438)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	264	Target Neighborhood Hits	55	Shared Neighborhood Hits	13
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MMP12_HUMAN
NC score	0.008361 (rank : 439)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	264	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	P39900	Gene names	MMP12, HME
Domain Architecture
Description	Macrophage metalloelastase precursor (EC 3.4.24.65) (HME) (Matrix metalloproteinase-12) (MMP-12) (Macrophage elastase) (ME).

IRS2_HUMAN
NC score	0.008086 (rank : 440)	θ value	0.813845 (rank : 162)
Query Neighborhood Hits	264	Target Neighborhood Hits	262	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

K1802_HUMAN
NC score	0.007724 (rank : 441)	θ value	0.0736092 (rank : 108)
Query Neighborhood Hits	264	Target Neighborhood Hits	1378	Shared Neighborhood Hits	29
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MMP8_HUMAN
NC score	0.007645 (rank : 442)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	264	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	P22894, Q45F99	Gene names	MMP8, CLG1
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL).

MMP8_MOUSE
NC score	0.007489 (rank : 443)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	264	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	O70138, O88733	Gene names	Mmp8
Domain Architecture
Description	Neutrophil collagenase precursor (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (Collagenase 2).

COX11_MOUSE
NC score	0.007247 (rank : 444)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	264	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P8I6	Gene names	Cox11
Domain Architecture	No domain graphic available
Description	Cytochrome c oxidase assembly protein COX11, mitochondrial precursor.

PO121_MOUSE
NC score	0.006681 (rank : 445)	θ value	2.36792 (rank : 203)
Query Neighborhood Hits	264	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

HAIR_MOUSE
NC score	0.005715 (rank : 446)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	264	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

CNOT3_HUMAN
NC score	0.005511 (rank : 447)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	264	Target Neighborhood Hits	425	Shared Neighborhood Hits	8
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

YLPM1_HUMAN
NC score	0.003985 (rank : 448)	θ value	3.0926 (rank : 218)
Query Neighborhood Hits	264	Target Neighborhood Hits	670	Shared Neighborhood Hits	13
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

PER1_HUMAN
NC score	0.003529 (rank : 449)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	264	Target Neighborhood Hits	215	Shared Neighborhood Hits	9
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

IQEC2_HUMAN
NC score	0.003058 (rank : 450)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	264	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

KCNKH_HUMAN
NC score	0.002831 (rank : 451)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	264	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

PLD2_HUMAN
NC score	0.002776 (rank : 452)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	264	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14939, O43540, O43579, O43580, Q96BY3	Gene names	PLD2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (hPLD2).

IQEC2_MOUSE
NC score	0.002523 (rank : 453)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	264	Target Neighborhood Hits	417	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

FOXC2_HUMAN
NC score	0.000086 (rank : 454)	θ value	2.36792 (rank : 197)
Query Neighborhood Hits	264	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

JIP3_HUMAN
NC score	-0.000795 (rank : 455)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	264	Target Neighborhood Hits	1039	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

PZRN3_MOUSE
NC score	-0.001673 (rank : 456)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	264	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PCDA9_HUMAN
NC score	-0.001738 (rank : 457)	θ value	3.0926 (rank : 213)
Query Neighborhood Hits	264	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

PZRN3_HUMAN
NC score	-0.001757 (rank : 458)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	264	Target Neighborhood Hits	461	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

HXA10_MOUSE
NC score	-0.001949 (rank : 459)	θ value	2.36792 (rank : 198)
Query Neighborhood Hits	264	Target Neighborhood Hits	365	Shared Neighborhood Hits	5
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

K1HB_HUMAN
NC score	-0.003038 (rank : 460)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	264	Target Neighborhood Hits	470	Shared Neighborhood Hits	11
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).

HXA3_MOUSE
NC score	-0.003446 (rank : 461)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	264	Target Neighborhood Hits	558	Shared Neighborhood Hits	11
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

OTP_MOUSE
NC score	-0.003471 (rank : 462)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	264	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

RON_MOUSE
NC score	-0.005654 (rank : 463)	θ value	3.0926 (rank : 216)
Query Neighborhood Hits	264	Target Neighborhood Hits	836	Shared Neighborhood Hits	11
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

MTR1L_HUMAN
NC score	-0.006425 (rank : 464)	θ value	1.06291 (rank : 172)
Query Neighborhood Hits	264	Target Neighborhood Hits	1180	Shared Neighborhood Hits	15
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

SALL3_HUMAN
NC score	-0.006544 (rank : 465)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	264	Target Neighborhood Hits	1066	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

TAOK1_MOUSE
NC score	-0.009325 (rank : 466)	θ value	1.38821 (rank : 187)
Query Neighborhood Hits	264	Target Neighborhood Hits	1720	Shared Neighborhood Hits	10
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

TAOK1_HUMAN
NC score	-0.009479 (rank : 467)	θ value	2.36792 (rank : 204)
Query Neighborhood Hits	264	Target Neighborhood Hits	1734	Shared Neighborhood Hits	10
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).