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Network neighborhood for query Sequence : PLD2_HUMAN

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PLD2_HUMAN
SwissProt Accessions	O14939, O43540, O43579, O43580, Q96BY3	Gene names	PLD2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (hPLD2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PLD2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	O14939, O43540, O43579, O43580, Q96BY3	Gene names	PLD2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (hPLD2).

PLD2_MOUSE
θ value	0 (rank : 2)	NC score	0.998196 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P97813	Gene names	Pld2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (mPLD2).

PLD1_HUMAN
θ value	5.76203e-156 (rank : 3)	NC score	0.938320 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

PLD1_MOUSE
θ value	5.76203e-156 (rank : 4)	NC score	0.938704 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

PXK_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.041176 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

CENA1_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.031050 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

MYO10_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.012745 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	920	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

SNPC4_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.030250 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	237	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

SNX23_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.010699 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	944	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

WNK3_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.003264 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	948	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

PXK_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.030758 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	320	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

ILDR1_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.016807 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

SOS1_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.011076 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.011029 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	281	Shared Neighborhood Hits	3
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

ADA33_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.002776 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

Hits sorted by NC score

PLD2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	O14939, O43540, O43579, O43580, Q96BY3	Gene names	PLD2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (hPLD2).

PLD2_MOUSE
NC score	0.998196 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P97813	Gene names	Pld2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (mPLD2).

PLD1_MOUSE
NC score	0.938704 (rank : 3)	θ value	5.76203e-156 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

PLD1_HUMAN
NC score	0.938320 (rank : 4)	θ value	5.76203e-156 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

PXK_HUMAN
NC score	0.041176 (rank : 5)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

CENA1_HUMAN
NC score	0.031050 (rank : 6)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

PXK_MOUSE
NC score	0.030758 (rank : 7)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	320	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SNPC4_MOUSE
NC score	0.030250 (rank : 8)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	237	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

ILDR1_HUMAN
NC score	0.016807 (rank : 9)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

MYO10_HUMAN
NC score	0.012745 (rank : 10)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	920	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

SOS1_HUMAN
NC score	0.011076 (rank : 11)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
NC score	0.011029 (rank : 12)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	281	Shared Neighborhood Hits	3
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SNX23_HUMAN
NC score	0.010699 (rank : 13)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	944	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

WNK3_HUMAN
NC score	0.003264 (rank : 14)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	948	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

ADA33_HUMAN
NC score	0.002776 (rank : 15)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).