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Network neighborhood for query Sequence : PLD1_MOUSE

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PLD1_MOUSE
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PLD1_HUMAN
θ value	0 (rank : 1)	NC score	0.998306 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

PLD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

PLD2_MOUSE
θ value	1.37145e-157 (rank : 3)	NC score	0.939233 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P97813	Gene names	Pld2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (mPLD2).

PLD2_HUMAN
θ value	5.76203e-156 (rank : 4)	NC score	0.938704 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	O14939, O43540, O43579, O43580, Q96BY3	Gene names	PLD2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (hPLD2).

CENB1_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.039399 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	383	Shared Neighborhood Hits	5
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

SNX27_HUMAN
θ value	0.365318 (rank : 6)	NC score	0.059254 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q96L92	Gene names	SNX27
Domain Architecture
Description	Sorting nexin-27.

DNL3_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.028752 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

SNX23_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.009873 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	944	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

SYNE1_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.007043 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	1484	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TSSP_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.017201 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXE5	Gene names	Prss16, Tssp
Domain Architecture
Description	Thymus-specific serine protease precursor (EC 3.4.-.-).

UTP6_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.024240 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCY6, Q8CH76	Gene names	Utp6, Mhat
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein).

CP39A_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.012804 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKJ9	Gene names	Cyp39a1
Domain Architecture
Description	Cytochrome P450 39A1 (EC 1.14.13.99) (24-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1).

DDX21_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.004863 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	308	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

FYB_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.015987 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

SNX14_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.020506 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

SYNE2_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.010251 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	1323	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CENB5_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.013097 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	395	Shared Neighborhood Hits	4
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

FA8_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.008166 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

LCOR_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.017415 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JN0, Q5VW16, Q7Z723, Q86T32, Q86T33, Q8N3L6	Gene names	LCOR, KIAA1795, MLR2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

LCOR_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.017396 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

PRKDC_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.007547 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

UTP6_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.020101 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYH9, Q8IX96, Q96BL2, Q9NQ91	Gene names	UTP6, C17orf40, HCA66, MHAT
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein) (Hepatocellular carcinoma-associated antigen 66).

ZN596_HUMAN
θ value	8.99809 (rank : 23)	NC score	-0.000923 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	716	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TC21, O95015, Q8N9X0	Gene names	ZNF596
Domain Architecture	No domain graphic available
Description	Zinc finger protein 596.

Hits sorted by NC score

PLD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

PLD1_HUMAN
NC score	0.998306 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

PLD2_MOUSE
NC score	0.939233 (rank : 3)	θ value	1.37145e-157 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P97813	Gene names	Pld2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (mPLD2).

PLD2_HUMAN
NC score	0.938704 (rank : 4)	θ value	5.76203e-156 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	O14939, O43540, O43579, O43580, Q96BY3	Gene names	PLD2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (hPLD2).

SNX27_HUMAN
NC score	0.059254 (rank : 5)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q96L92	Gene names	SNX27
Domain Architecture
Description	Sorting nexin-27.

CENB1_HUMAN
NC score	0.039399 (rank : 6)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	383	Shared Neighborhood Hits	5
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DNL3_HUMAN
NC score	0.028752 (rank : 7)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

UTP6_MOUSE
NC score	0.024240 (rank : 8)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCY6, Q8CH76	Gene names	Utp6, Mhat
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein).

SNX14_HUMAN
NC score	0.020506 (rank : 9)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5W7, Q9BSD1	Gene names	SNX14
Domain Architecture
Description	Sorting nexin-14.

UTP6_HUMAN
NC score	0.020101 (rank : 10)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYH9, Q8IX96, Q96BL2, Q9NQ91	Gene names	UTP6, C17orf40, HCA66, MHAT
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein) (Hepatocellular carcinoma-associated antigen 66).

LCOR_HUMAN
NC score	0.017415 (rank : 11)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JN0, Q5VW16, Q7Z723, Q86T32, Q86T33, Q8N3L6	Gene names	LCOR, KIAA1795, MLR2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

LCOR_MOUSE
NC score	0.017396 (rank : 12)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

TSSP_MOUSE
NC score	0.017201 (rank : 13)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXE5	Gene names	Prss16, Tssp
Domain Architecture
Description	Thymus-specific serine protease precursor (EC 3.4.-.-).

FYB_MOUSE
NC score	0.015987 (rank : 14)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

CENB5_HUMAN
NC score	0.013097 (rank : 15)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	395	Shared Neighborhood Hits	4
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CP39A_MOUSE
NC score	0.012804 (rank : 16)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKJ9	Gene names	Cyp39a1
Domain Architecture
Description	Cytochrome P450 39A1 (EC 1.14.13.99) (24-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1).

SYNE2_HUMAN
NC score	0.010251 (rank : 17)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	1323	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

SNX23_HUMAN
NC score	0.009873 (rank : 18)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	944	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

FA8_MOUSE
NC score	0.008166 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

PRKDC_HUMAN
NC score	0.007547 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

SYNE1_HUMAN
NC score	0.007043 (rank : 21)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	1484	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

DDX21_HUMAN
NC score	0.004863 (rank : 22)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	308	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

ZN596_HUMAN
NC score	-0.000923 (rank : 23)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	716	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TC21, O95015, Q8N9X0	Gene names	ZNF596
Domain Architecture	No domain graphic available
Description	Zinc finger protein 596.