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Network neighborhood for query Sequence : BAI1_HUMAN

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BAI1_HUMAN
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BAI1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	375	Target Neighborhood Hits	375	Shared Neighborhood Hits	375
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	0 (rank : 2)	NC score	0.995357 (rank : 2)
Query Neighborhood Hits	375	Target Neighborhood Hits	340	Shared Neighborhood Hits	286
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	0 (rank : 3)	NC score	0.976087 (rank : 6)
Query Neighborhood Hits	375	Target Neighborhood Hits	332	Shared Neighborhood Hits	198
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	0 (rank : 4)	NC score	0.976707 (rank : 5)
Query Neighborhood Hits	375	Target Neighborhood Hits	323	Shared Neighborhood Hits	196
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	0 (rank : 5)	NC score	0.980568 (rank : 4)
Query Neighborhood Hits	375	Target Neighborhood Hits	246	Shared Neighborhood Hits	182
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	0 (rank : 6)	NC score	0.981146 (rank : 3)
Query Neighborhood Hits	375	Target Neighborhood Hits	250	Shared Neighborhood Hits	186
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

HMCN1_HUMAN
θ value	1.2325e-65 (rank : 7)	NC score	0.351758 (rank : 133)
Query Neighborhood Hits	375	Target Neighborhood Hits	983	Shared Neighborhood Hits	135
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CELR1_HUMAN
θ value	1.72781e-51 (rank : 8)	NC score	0.361904 (rank : 126)
Query Neighborhood Hits	375	Target Neighborhood Hits	613	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	1.41672e-45 (rank : 9)	NC score	0.357336 (rank : 130)
Query Neighborhood Hits	375	Target Neighborhood Hits	617	Shared Neighborhood Hits	127
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

PROP_MOUSE
θ value	7.03111e-45 (rank : 10)	NC score	0.716772 (rank : 7)
Query Neighborhood Hits	375	Target Neighborhood Hits	165	Shared Neighborhood Hits	93
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

CELR2_MOUSE
θ value	1.32601e-43 (rank : 11)	NC score	0.357007 (rank : 131)
Query Neighborhood Hits	375	Target Neighborhood Hits	584	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR2_HUMAN
θ value	2.95404e-43 (rank : 12)	NC score	0.349941 (rank : 134)
Query Neighborhood Hits	375	Target Neighborhood Hits	657	Shared Neighborhood Hits	126
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

SEM5B_MOUSE
θ value	8.04462e-41 (rank : 13)	NC score	0.462638 (rank : 74)
Query Neighborhood Hits	375	Target Neighborhood Hits	190	Shared Neighborhood Hits	96
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5B_HUMAN
θ value	1.05066e-40 (rank : 14)	NC score	0.460175 (rank : 77)
Query Neighborhood Hits	375	Target Neighborhood Hits	178	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

CELR3_HUMAN
θ value	1.16164e-39 (rank : 15)	NC score	0.330079 (rank : 141)
Query Neighborhood Hits	375	Target Neighborhood Hits	680	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

TSP2_HUMAN
θ value	4.41421e-39 (rank : 16)	NC score	0.537049 (rank : 40)
Query Neighborhood Hits	375	Target Neighborhood Hits	359	Shared Neighborhood Hits	118
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP1_MOUSE
θ value	7.52953e-39 (rank : 17)	NC score	0.530369 (rank : 42)
Query Neighborhood Hits	375	Target Neighborhood Hits	396	Shared Neighborhood Hits	117
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

LPHN1_HUMAN
θ value	1.6774e-38 (rank : 18)	NC score	0.636572 (rank : 18)
Query Neighborhood Hits	375	Target Neighborhood Hits	155	Shared Neighborhood Hits	91
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

TSP1_HUMAN
θ value	1.6774e-38 (rank : 19)	NC score	0.527141 (rank : 46)
Query Neighborhood Hits	375	Target Neighborhood Hits	389	Shared Neighborhood Hits	118
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

CELR3_MOUSE
θ value	2.19075e-38 (rank : 20)	NC score	0.329648 (rank : 142)
Query Neighborhood Hits	375	Target Neighborhood Hits	687	Shared Neighborhood Hits	133
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

LPHN2_HUMAN
θ value	4.88048e-38 (rank : 21)	NC score	0.627555 (rank : 25)
Query Neighborhood Hits	375	Target Neighborhood Hits	136	Shared Neighborhood Hits	84
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

TSP2_MOUSE
θ value	1.08726e-37 (rank : 22)	NC score	0.537064 (rank : 39)
Query Neighborhood Hits	375	Target Neighborhood Hits	352	Shared Neighborhood Hits	119
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

LPHN3_HUMAN
θ value	1.42001e-37 (rank : 23)	NC score	0.634118 (rank : 21)
Query Neighborhood Hits	375	Target Neighborhood Hits	139	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

SSPO_MOUSE
θ value	3.16345e-37 (rank : 24)	NC score	0.433688 (rank : 100)
Query Neighborhood Hits	375	Target Neighborhood Hits	800	Shared Neighborhood Hits	151
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

EMR4_MOUSE
θ value	1.20211e-36 (rank : 25)	NC score	0.691238 (rank : 10)
Query Neighborhood Hits	375	Target Neighborhood Hits	191	Shared Neighborhood Hits	87
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

PROP_HUMAN
θ value	1.20211e-36 (rank : 26)	NC score	0.707188 (rank : 8)
Query Neighborhood Hits	375	Target Neighborhood Hits	126	Shared Neighborhood Hits	92
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

GP133_HUMAN
θ value	4.568e-36 (rank : 27)	NC score	0.706017 (rank : 9)
Query Neighborhood Hits	375	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

SEM5A_HUMAN
θ value	8.61488e-35 (rank : 28)	NC score	0.460943 (rank : 76)
Query Neighborhood Hits	375	Target Neighborhood Hits	177	Shared Neighborhood Hits	92
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

EMR1_MOUSE
θ value	7.29293e-34 (rank : 29)	NC score	0.515006 (rank : 51)
Query Neighborhood Hits	375	Target Neighborhood Hits	349	Shared Neighborhood Hits	99
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

SEM5A_MOUSE
θ value	1.24399e-33 (rank : 30)	NC score	0.455401 (rank : 83)
Query Neighborhood Hits	375	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

CD97_HUMAN
θ value	1.37539e-32 (rank : 31)	NC score	0.518788 (rank : 48)
Query Neighborhood Hits	375	Target Neighborhood Hits	353	Shared Neighborhood Hits	101
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

GP113_HUMAN
θ value	1.08979e-29 (rank : 32)	NC score	0.688484 (rank : 11)
Query Neighborhood Hits	375	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

ELTD1_MOUSE
θ value	1.4233e-29 (rank : 33)	NC score	0.582142 (rank : 35)
Query Neighborhood Hits	375	Target Neighborhood Hits	288	Shared Neighborhood Hits	99
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR3_HUMAN
θ value	1.4233e-29 (rank : 34)	NC score	0.652461 (rank : 16)
Query Neighborhood Hits	375	Target Neighborhood Hits	245	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

ELTD1_HUMAN
θ value	1.85889e-29 (rank : 35)	NC score	0.653374 (rank : 15)
Query Neighborhood Hits	375	Target Neighborhood Hits	269	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

SPON1_HUMAN
θ value	2.96777e-27 (rank : 36)	NC score	0.635530 (rank : 20)
Query Neighborhood Hits	375	Target Neighborhood Hits	117	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	2.96777e-27 (rank : 37)	NC score	0.636357 (rank : 19)
Query Neighborhood Hits	375	Target Neighborhood Hits	123	Shared Neighborhood Hits	98
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

EMR1_HUMAN
θ value	9.54697e-26 (rank : 38)	NC score	0.489217 (rank : 55)
Query Neighborhood Hits	375	Target Neighborhood Hits	382	Shared Neighborhood Hits	103
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

GP112_HUMAN
θ value	1.05554e-24 (rank : 39)	NC score	0.609566 (rank : 31)
Query Neighborhood Hits	375	Target Neighborhood Hits	441	Shared Neighborhood Hits	111
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

EMR2_HUMAN
θ value	1.37858e-24 (rank : 40)	NC score	0.499401 (rank : 52)
Query Neighborhood Hits	375	Target Neighborhood Hits	345	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

GP110_HUMAN
θ value	1.5242e-23 (rank : 41)	NC score	0.630585 (rank : 23)
Query Neighborhood Hits	375	Target Neighborhood Hits	87	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GPR64_HUMAN
θ value	1.99067e-23 (rank : 42)	NC score	0.662564 (rank : 14)
Query Neighborhood Hits	375	Target Neighborhood Hits	207	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	2.59989e-23 (rank : 43)	NC score	0.664686 (rank : 13)
Query Neighborhood Hits	375	Target Neighborhood Hits	156	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

ATS9_HUMAN
θ value	3.39556e-23 (rank : 44)	NC score	0.487296 (rank : 56)
Query Neighborhood Hits	375	Target Neighborhood Hits	219	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

CD97_MOUSE
θ value	9.87957e-23 (rank : 45)	NC score	0.554007 (rank : 38)
Query Neighborhood Hits	375	Target Neighborhood Hits	295	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

UNC5B_HUMAN
θ value	1.6852e-22 (rank : 46)	NC score	0.527283 (rank : 45)
Query Neighborhood Hits	375	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5A_MOUSE
θ value	3.75424e-22 (rank : 47)	NC score	0.534337 (rank : 41)
Query Neighborhood Hits	375	Target Neighborhood Hits	203	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_MOUSE
θ value	3.75424e-22 (rank : 48)	NC score	0.529054 (rank : 43)
Query Neighborhood Hits	375	Target Neighborhood Hits	226	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

GP128_HUMAN
θ value	4.9032e-22 (rank : 49)	NC score	0.665736 (rank : 12)
Query Neighborhood Hits	375	Target Neighborhood Hits	135	Shared Neighborhood Hits	84
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GPR97_MOUSE
θ value	1.42661e-21 (rank : 50)	NC score	0.644057 (rank : 17)
Query Neighborhood Hits	375	Target Neighborhood Hits	89	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

UNC5C_MOUSE
θ value	1.42661e-21 (rank : 51)	NC score	0.516096 (rank : 50)
Query Neighborhood Hits	375	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

GP116_HUMAN
θ value	1.86321e-21 (rank : 52)	NC score	0.626919 (rank : 26)
Query Neighborhood Hits	375	Target Neighborhood Hits	167	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

UNC5C_HUMAN
θ value	1.86321e-21 (rank : 53)	NC score	0.516121 (rank : 49)
Query Neighborhood Hits	375	Target Neighborhood Hits	226	Shared Neighborhood Hits	82
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

GP144_HUMAN
θ value	5.42112e-21 (rank : 54)	NC score	0.633205 (rank : 22)
Query Neighborhood Hits	375	Target Neighborhood Hits	108	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GP126_HUMAN
θ value	3.51386e-20 (rank : 55)	NC score	0.565571 (rank : 36)
Query Neighborhood Hits	375	Target Neighborhood Hits	187	Shared Neighborhood Hits	89
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

ATS18_MOUSE
θ value	1.74391e-19 (rank : 56)	NC score	0.484623 (rank : 57)
Query Neighborhood Hits	375	Target Neighborhood Hits	163	Shared Neighborhood Hits	87
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS20_MOUSE
θ value	3.88503e-19 (rank : 57)	NC score	0.478469 (rank : 64)
Query Neighborhood Hits	375	Target Neighborhood Hits	225	Shared Neighborhood Hits	97
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS18_HUMAN
θ value	1.13037e-18 (rank : 58)	NC score	0.479454 (rank : 61)
Query Neighborhood Hits	375	Target Neighborhood Hits	169	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

GP110_MOUSE
θ value	3.28887e-18 (rank : 59)	NC score	0.621490 (rank : 27)
Query Neighborhood Hits	375	Target Neighborhood Hits	92	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP115_MOUSE
θ value	4.29542e-18 (rank : 60)	NC score	0.609320 (rank : 32)
Query Neighborhood Hits	375	Target Neighborhood Hits	69	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP115_HUMAN
θ value	5.60996e-18 (rank : 61)	NC score	0.607919 (rank : 33)
Query Neighborhood Hits	375	Target Neighborhood Hits	87	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GPR97_HUMAN
θ value	8.10077e-17 (rank : 62)	NC score	0.614626 (rank : 28)
Query Neighborhood Hits	375	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

ATS20_HUMAN
θ value	1.38178e-16 (rank : 63)	NC score	0.468915 (rank : 69)
Query Neighborhood Hits	375	Target Neighborhood Hits	192	Shared Neighborhood Hits	99
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

UNC5D_MOUSE
θ value	2.35696e-16 (rank : 64)	NC score	0.491831 (rank : 54)
Query Neighborhood Hits	375	Target Neighborhood Hits	268	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ATS17_HUMAN
θ value	4.02038e-16 (rank : 65)	NC score	0.477542 (rank : 66)
Query Neighborhood Hits	375	Target Neighborhood Hits	194	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

UNC5D_HUMAN
θ value	5.25075e-16 (rank : 66)	NC score	0.493514 (rank : 53)
Query Neighborhood Hits	375	Target Neighborhood Hits	267	Shared Neighborhood Hits	81
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ATL2_HUMAN
θ value	6.85773e-16 (rank : 67)	NC score	0.526627 (rank : 47)
Query Neighborhood Hits	375	Target Neighborhood Hits	125	Shared Neighborhood Hits	85
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATS16_MOUSE
θ value	6.85773e-16 (rank : 68)	NC score	0.480727 (rank : 60)
Query Neighborhood Hits	375	Target Neighborhood Hits	179	Shared Neighborhood Hits	92
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATL2_MOUSE
θ value	8.95645e-16 (rank : 69)	NC score	0.528141 (rank : 44)
Query Neighborhood Hits	375	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATS19_MOUSE
θ value	1.99529e-15 (rank : 70)	NC score	0.457752 (rank : 79)
Query Neighborhood Hits	375	Target Neighborhood Hits	188	Shared Neighborhood Hits	84
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_HUMAN
θ value	5.8054e-15 (rank : 71)	NC score	0.452061 (rank : 87)
Query Neighborhood Hits	375	Target Neighborhood Hits	203	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

GP111_HUMAN
θ value	7.58209e-15 (rank : 72)	NC score	0.561220 (rank : 37)
Query Neighborhood Hits	375	Target Neighborhood Hits	77	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

ATS16_HUMAN
θ value	9.90251e-15 (rank : 73)	NC score	0.478978 (rank : 62)
Query Neighborhood Hits	375	Target Neighborhood Hits	208	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATL3_HUMAN
θ value	2.88119e-14 (rank : 74)	NC score	0.436877 (rank : 97)
Query Neighborhood Hits	375	Target Neighborhood Hits	414	Shared Neighborhood Hits	94
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

GPR56_HUMAN
θ value	1.42992e-13 (rank : 75)	NC score	0.614448 (rank : 29)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GP125_HUMAN
θ value	1.86753e-13 (rank : 76)	NC score	0.330136 (rank : 140)
Query Neighborhood Hits	375	Target Neighborhood Hits	327	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP114_HUMAN
θ value	3.18553e-13 (rank : 77)	NC score	0.612376 (rank : 30)
Query Neighborhood Hits	375	Target Neighborhood Hits	75	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

CALCR_HUMAN
θ value	5.43371e-13 (rank : 78)	NC score	0.443221 (rank : 95)
Query Neighborhood Hits	375	Target Neighborhood Hits	67	Shared Neighborhood Hits	66
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

CRFR1_HUMAN
θ value	1.2105e-12 (rank : 79)	NC score	0.476604 (rank : 67)
Query Neighborhood Hits	375	Target Neighborhood Hits	82	Shared Neighborhood Hits	74
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

GP128_MOUSE
θ value	1.58096e-12 (rank : 80)	NC score	0.628042 (rank : 24)
Query Neighborhood Hits	375	Target Neighborhood Hits	141	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

ATS13_HUMAN
θ value	2.69671e-12 (rank : 81)	NC score	0.483493 (rank : 58)
Query Neighborhood Hits	375	Target Neighborhood Hits	238	Shared Neighborhood Hits	89
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

CRFR1_MOUSE
θ value	2.69671e-12 (rank : 82)	NC score	0.481194 (rank : 59)
Query Neighborhood Hits	375	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

CRFR2_HUMAN
θ value	2.69671e-12 (rank : 83)	NC score	0.473292 (rank : 68)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	75
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

ATS14_HUMAN
θ value	3.52202e-12 (rank : 84)	NC score	0.462839 (rank : 73)
Query Neighborhood Hits	375	Target Neighborhood Hits	382	Shared Neighborhood Hits	112
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS1_MOUSE
θ value	7.84624e-12 (rank : 85)	NC score	0.452723 (rank : 86)
Query Neighborhood Hits	375	Target Neighborhood Hits	158	Shared Neighborhood Hits	87
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

CRFR2_MOUSE
θ value	1.02475e-11 (rank : 86)	NC score	0.477639 (rank : 65)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	75
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

GPR98_HUMAN
θ value	1.02475e-11 (rank : 87)	NC score	0.446992 (rank : 91)
Query Neighborhood Hits	375	Target Neighborhood Hits	202	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GP125_MOUSE
θ value	1.33837e-11 (rank : 88)	NC score	0.308973 (rank : 146)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

ATS1_HUMAN
θ value	1.74796e-11 (rank : 89)	NC score	0.450429 (rank : 89)
Query Neighborhood Hits	375	Target Neighborhood Hits	159	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS2_HUMAN
θ value	1.133e-10 (rank : 90)	NC score	0.466139 (rank : 71)
Query Neighborhood Hits	375	Target Neighborhood Hits	179	Shared Neighborhood Hits	86
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	1.133e-10 (rank : 91)	NC score	0.446958 (rank : 92)
Query Neighborhood Hits	375	Target Neighborhood Hits	179	Shared Neighborhood Hits	89
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

VIPR2_HUMAN
θ value	3.29651e-10 (rank : 92)	NC score	0.414399 (rank : 107)
Query Neighborhood Hits	375	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

ATS12_MOUSE
θ value	4.30538e-10 (rank : 93)	NC score	0.456244 (rank : 80)
Query Neighborhood Hits	375	Target Neighborhood Hits	220	Shared Neighborhood Hits	93
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

GPR98_MOUSE
θ value	4.30538e-10 (rank : 94)	NC score	0.434594 (rank : 99)
Query Neighborhood Hits	375	Target Neighborhood Hits	206	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

GPR56_MOUSE
θ value	7.34386e-10 (rank : 95)	NC score	0.593526 (rank : 34)
Query Neighborhood Hits	375	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

ATS12_HUMAN
θ value	9.59137e-10 (rank : 96)	NC score	0.455661 (rank : 82)
Query Neighborhood Hits	375	Target Neighborhood Hits	251	Shared Neighborhood Hits	96
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS2_MOUSE
θ value	9.59137e-10 (rank : 97)	NC score	0.463222 (rank : 72)
Query Neighborhood Hits	375	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS6_HUMAN
θ value	9.59137e-10 (rank : 98)	NC score	0.447101 (rank : 90)
Query Neighborhood Hits	375	Target Neighborhood Hits	141	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

CILP2_HUMAN
θ value	1.25267e-09 (rank : 99)	NC score	0.383625 (rank : 117)
Query Neighborhood Hits	375	Target Neighborhood Hits	307	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

ATS8_MOUSE
θ value	1.63604e-09 (rank : 100)	NC score	0.456224 (rank : 81)
Query Neighborhood Hits	375	Target Neighborhood Hits	139	Shared Neighborhood Hits	84
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS7_HUMAN
θ value	2.13673e-09 (rank : 101)	NC score	0.445427 (rank : 93)
Query Neighborhood Hits	375	Target Neighborhood Hits	169	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS15_HUMAN
θ value	3.64472e-09 (rank : 102)	NC score	0.443777 (rank : 94)
Query Neighborhood Hits	375	Target Neighborhood Hits	151	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS13_MOUSE
θ value	4.76016e-09 (rank : 103)	NC score	0.478930 (rank : 63)
Query Neighborhood Hits	375	Target Neighborhood Hits	227	Shared Neighborhood Hits	94
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS4_MOUSE
θ value	4.76016e-09 (rank : 104)	NC score	0.453734 (rank : 85)
Query Neighborhood Hits	375	Target Neighborhood Hits	145	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS8_HUMAN
θ value	8.11959e-09 (rank : 105)	NC score	0.451981 (rank : 88)
Query Neighborhood Hits	375	Target Neighborhood Hits	145	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

CALCR_MOUSE
θ value	8.11959e-09 (rank : 106)	NC score	0.422833 (rank : 104)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	70
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

VIPR2_MOUSE
θ value	8.11959e-09 (rank : 107)	NC score	0.418623 (rank : 106)
Query Neighborhood Hits	375	Target Neighborhood Hits	98	Shared Neighborhood Hits	75
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

CI094_HUMAN
θ value	1.06045e-08 (rank : 108)	NC score	0.368257 (rank : 123)
Query Neighborhood Hits	375	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ATS4_HUMAN
θ value	1.38499e-08 (rank : 109)	NC score	0.453955 (rank : 84)
Query Neighborhood Hits	375	Target Neighborhood Hits	138	Shared Neighborhood Hits	78
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

CO6_HUMAN
θ value	1.38499e-08 (rank : 110)	NC score	0.393192 (rank : 114)
Query Neighborhood Hits	375	Target Neighborhood Hits	331	Shared Neighborhood Hits	101
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

GP124_MOUSE
θ value	2.36244e-08 (rank : 111)	NC score	0.320581 (rank : 144)
Query Neighborhood Hits	375	Target Neighborhood Hits	423	Shared Neighborhood Hits	66
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

PTHR1_HUMAN
θ value	2.36244e-08 (rank : 112)	NC score	0.406303 (rank : 109)
Query Neighborhood Hits	375	Target Neighborhood Hits	85	Shared Neighborhood Hits	77
SwissProt Accessions	Q03431	Gene names	PTHR1, PTHR
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

UNC5A_HUMAN
θ value	3.08544e-08 (rank : 113)	NC score	0.406135 (rank : 110)
Query Neighborhood Hits	375	Target Neighborhood Hits	198	Shared Neighborhood Hits	76
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

VIPR1_MOUSE
θ value	3.08544e-08 (rank : 114)	NC score	0.419031 (rank : 105)
Query Neighborhood Hits	375	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	P97751, Q9JI40, Q9R1T8	Gene names	Vipr1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (VPAC1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

PTHR1_MOUSE
θ value	4.0297e-08 (rank : 115)	NC score	0.391061 (rank : 115)
Query Neighborhood Hits	375	Target Neighborhood Hits	90	Shared Neighborhood Hits	75
SwissProt Accessions	P41593, Q62119	Gene names	Pthr1, Pthr
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

ATS5_MOUSE
θ value	6.87365e-08 (rank : 116)	NC score	0.432346 (rank : 101)
Query Neighborhood Hits	375	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

GLR_HUMAN
θ value	6.87365e-08 (rank : 117)	NC score	0.380763 (rank : 119)
Query Neighborhood Hits	375	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	P47871	Gene names	GCGR
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

ATS5_HUMAN
θ value	1.53129e-07 (rank : 118)	NC score	0.424460 (rank : 103)
Query Neighborhood Hits	375	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

GP123_HUMAN
θ value	2.61198e-07 (rank : 119)	NC score	0.435826 (rank : 98)
Query Neighborhood Hits	375	Target Neighborhood Hits	120	Shared Neighborhood Hits	48
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

VIPR1_HUMAN
θ value	2.61198e-07 (rank : 120)	NC score	0.397040 (rank : 111)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	72
SwissProt Accessions	P32241, Q15871	Gene names	VIPR1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

ATL5_HUMAN
θ value	1.69304e-06 (rank : 121)	NC score	0.466211 (rank : 70)
Query Neighborhood Hits	375	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL1_HUMAN
θ value	2.21117e-06 (rank : 122)	NC score	0.462257 (rank : 75)
Query Neighborhood Hits	375	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

GLR_MOUSE
θ value	2.88788e-06 (rank : 123)	NC score	0.364506 (rank : 125)
Query Neighborhood Hits	375	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

THSD1_HUMAN
θ value	2.88788e-06 (rank : 124)	NC score	0.437579 (rank : 96)
Query Neighborhood Hits	375	Target Neighborhood Hits	136	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CO8B_MOUSE
θ value	3.77169e-06 (rank : 125)	NC score	0.381360 (rank : 118)
Query Neighborhood Hits	375	Target Neighborhood Hits	224	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

GP124_HUMAN
θ value	3.77169e-06 (rank : 126)	NC score	0.294864 (rank : 147)
Query Neighborhood Hits	375	Target Neighborhood Hits	304	Shared Neighborhood Hits	53
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CO8B_HUMAN
θ value	6.43352e-06 (rank : 127)	NC score	0.358894 (rank : 128)
Query Neighborhood Hits	375	Target Neighborhood Hits	199	Shared Neighborhood Hits	78
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

THSD1_MOUSE
θ value	6.43352e-06 (rank : 128)	NC score	0.427953 (rank : 102)
Query Neighborhood Hits	375	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ATL1_MOUSE
θ value	1.87187e-05 (rank : 129)	NC score	0.458695 (rank : 78)
Query Neighborhood Hits	375	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

CALRL_MOUSE
θ value	1.87187e-05 (rank : 130)	NC score	0.389667 (rank : 116)
Query Neighborhood Hits	375	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R1W5, Q9QXH8, Q9WUP2	Gene names	Calcrl, Crlr
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

PACR_MOUSE
θ value	1.87187e-05 (rank : 131)	NC score	0.411280 (rank : 108)
Query Neighborhood Hits	375	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	P70205	Gene names	Adcyap1r1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

CALRL_HUMAN
θ value	2.44474e-05 (rank : 132)	NC score	0.394069 (rank : 113)
Query Neighborhood Hits	375	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q16602	Gene names	CALCRL, CGRPR
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

CILP1_MOUSE
θ value	2.44474e-05 (rank : 133)	NC score	0.310253 (rank : 145)
Query Neighborhood Hits	375	Target Neighborhood Hits	282	Shared Neighborhood Hits	86
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

SCTR_HUMAN
θ value	3.19293e-05 (rank : 134)	NC score	0.377103 (rank : 121)
Query Neighborhood Hits	375	Target Neighborhood Hits	70	Shared Neighborhood Hits	67
SwissProt Accessions	P47872, Q12961, Q13213	Gene names	SCTR
Domain Architecture
Description	Secretin receptor precursor (SCT-R).

GHRHR_MOUSE
θ value	7.1131e-05 (rank : 135)	NC score	0.358486 (rank : 129)
Query Neighborhood Hits	375	Target Neighborhood Hits	79	Shared Neighborhood Hits	73
SwissProt Accessions	P32082	Gene names	Ghrhr, Grfr
Domain Architecture	No domain graphic available
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

CO8A_MOUSE
θ value	0.000121331 (rank : 136)	NC score	0.343102 (rank : 135)
Query Neighborhood Hits	375	Target Neighborhood Hits	182	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

GIPR_HUMAN
θ value	0.000121331 (rank : 137)	NC score	0.354433 (rank : 132)
Query Neighborhood Hits	375	Target Neighborhood Hits	71	Shared Neighborhood Hits	69
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

PACR_HUMAN
θ value	0.000121331 (rank : 138)	NC score	0.396750 (rank : 112)
Query Neighborhood Hits	375	Target Neighborhood Hits	86	Shared Neighborhood Hits	78
SwissProt Accessions	P41586	Gene names	ADCYAP1R1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

FZD3_HUMAN
θ value	0.000158464 (rank : 139)	NC score	0.107061 (rank : 188)
Query Neighborhood Hits	375	Target Neighborhood Hits	74	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD3_MOUSE
θ value	0.00020696 (rank : 140)	NC score	0.105886 (rank : 189)
Query Neighborhood Hits	375	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

GLP1R_MOUSE
θ value	0.00020696 (rank : 141)	NC score	0.380059 (rank : 120)
Query Neighborhood Hits	375	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

MUC1_HUMAN
θ value	0.000270298 (rank : 142)	NC score	0.038281 (rank : 502)
Query Neighborhood Hits	375	Target Neighborhood Hits	975	Shared Neighborhood Hits	83
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SCTR_MOUSE
θ value	0.000602161 (rank : 143)	NC score	0.361014 (rank : 127)
Query Neighborhood Hits	375	Target Neighborhood Hits	69	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWI2, Q80T66	Gene names	Sctr
Domain Architecture	No domain graphic available
Description	Secretin receptor precursor (SCT-R).

CILP1_HUMAN
θ value	0.000786445 (rank : 144)	NC score	0.292445 (rank : 148)
Query Neighborhood Hits	375	Target Neighborhood Hits	266	Shared Neighborhood Hits	87
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

OGFR_HUMAN
θ value	0.00102713 (rank : 145)	NC score	0.034985 (rank : 507)
Query Neighborhood Hits	375	Target Neighborhood Hits	1582	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CO7_HUMAN
θ value	0.00134147 (rank : 146)	NC score	0.332540 (rank : 139)
Query Neighborhood Hits	375	Target Neighborhood Hits	278	Shared Neighborhood Hits	82
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

FRAS1_HUMAN
θ value	0.00134147 (rank : 147)	NC score	0.113674 (rank : 176)
Query Neighborhood Hits	375	Target Neighborhood Hits	759	Shared Neighborhood Hits	87
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GHRHR_HUMAN
θ value	0.00134147 (rank : 148)	NC score	0.371277 (rank : 122)
Query Neighborhood Hits	375	Target Neighborhood Hits	78	Shared Neighborhood Hits	74
SwissProt Accessions	Q02643, Q99863	Gene names	GHRHR
Domain Architecture
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

CEL_HUMAN
θ value	0.00175202 (rank : 149)	NC score	0.029380 (rank : 523)
Query Neighborhood Hits	375	Target Neighborhood Hits	896	Shared Neighborhood Hits	81
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CO8A_HUMAN
θ value	0.00175202 (rank : 150)	NC score	0.341076 (rank : 136)
Query Neighborhood Hits	375	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

FZD6_MOUSE
θ value	0.00175202 (rank : 151)	NC score	0.088477 (rank : 272)
Query Neighborhood Hits	375	Target Neighborhood Hits	135	Shared Neighborhood Hits	33
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

MKL1_MOUSE
θ value	0.00228821 (rank : 152)	NC score	0.043948 (rank : 492)
Query Neighborhood Hits	375	Target Neighborhood Hits	667	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

GLP1R_HUMAN
θ value	0.00298849 (rank : 153)	NC score	0.366875 (rank : 124)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	69
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

NRX2A_HUMAN
θ value	0.00298849 (rank : 154)	NC score	0.080396 (rank : 298)
Query Neighborhood Hits	375	Target Neighborhood Hits	614	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.00298849 (rank : 155)	NC score	0.041875 (rank : 495)
Query Neighborhood Hits	375	Target Neighborhood Hits	481	Shared Neighborhood Hits	47
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SON_HUMAN
θ value	0.00298849 (rank : 156)	NC score	0.036713 (rank : 505)
Query Neighborhood Hits	375	Target Neighborhood Hits	1568	Shared Neighborhood Hits	108
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

FZD6_HUMAN
θ value	0.00509761 (rank : 157)	NC score	0.091619 (rank : 257)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

GLP2R_HUMAN
θ value	0.00665767 (rank : 158)	NC score	0.335271 (rank : 137)
Query Neighborhood Hits	375	Target Neighborhood Hits	75	Shared Neighborhood Hits	70
SwissProt Accessions	O95838	Gene names	GLP2R
Domain Architecture
Description	Glucagon-like peptide 2 receptor precursor (GLP-2 receptor) (GLP-2-R) (GLP-2R).

FRAS1_MOUSE
θ value	0.0113563 (rank : 159)	NC score	0.122110 (rank : 168)
Query Neighborhood Hits	375	Target Neighborhood Hits	747	Shared Neighborhood Hits	96
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PTHR2_MOUSE
θ value	0.0113563 (rank : 160)	NC score	0.323408 (rank : 143)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

PTHR2_HUMAN
θ value	0.0148317 (rank : 161)	NC score	0.335019 (rank : 138)
Query Neighborhood Hits	375	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P49190, Q8N429	Gene names	PTHR2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

RGS3_MOUSE
θ value	0.0148317 (rank : 162)	NC score	0.031949 (rank : 516)
Query Neighborhood Hits	375	Target Neighborhood Hits	1621	Shared Neighborhood Hits	106
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PRRT3_HUMAN
θ value	0.0193708 (rank : 163)	NC score	0.032435 (rank : 515)
Query Neighborhood Hits	375	Target Neighborhood Hits	998	Shared Neighborhood Hits	82
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SPON2_HUMAN
θ value	0.0252991 (rank : 164)	NC score	0.198324 (rank : 151)
Query Neighborhood Hits	375	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

WISP1_HUMAN
θ value	0.0330416 (rank : 165)	NC score	0.123949 (rank : 167)
Query Neighborhood Hits	375	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP1_MOUSE
θ value	0.0330416 (rank : 166)	NC score	0.131589 (rank : 162)
Query Neighborhood Hits	375	Target Neighborhood Hits	123	Shared Neighborhood Hits	55
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

GP157_HUMAN
θ value	0.0431538 (rank : 167)	NC score	0.256774 (rank : 149)
Query Neighborhood Hits	375	Target Neighborhood Hits	93	Shared Neighborhood Hits	61
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GAB1_MOUSE
θ value	0.0563607 (rank : 168)	NC score	0.032668 (rank : 513)
Query Neighborhood Hits	375	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PCLO_HUMAN
θ value	0.0563607 (rank : 169)	NC score	0.041828 (rank : 496)
Query Neighborhood Hits	375	Target Neighborhood Hits	2046	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

IL4RA_HUMAN
θ value	0.0736092 (rank : 170)	NC score	0.034807 (rank : 509)
Query Neighborhood Hits	375	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

RSPO1_HUMAN
θ value	0.0736092 (rank : 171)	NC score	0.157066 (rank : 153)
Query Neighborhood Hits	375	Target Neighborhood Hits	101	Shared Neighborhood Hits	52
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

ATX7_MOUSE
θ value	0.0961366 (rank : 172)	NC score	0.040112 (rank : 499)
Query Neighborhood Hits	375	Target Neighborhood Hits	328	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

GP157_MOUSE
θ value	0.0961366 (rank : 173)	NC score	0.248798 (rank : 150)
Query Neighborhood Hits	375	Target Neighborhood Hits	78	Shared Neighborhood Hits	60
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

RSPO3_MOUSE
θ value	0.0961366 (rank : 174)	NC score	0.130415 (rank : 163)
Query Neighborhood Hits	375	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

ZN687_HUMAN
θ value	0.0961366 (rank : 175)	NC score	0.000087 (rank : 647)
Query Neighborhood Hits	375	Target Neighborhood Hits	1244	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

MAST4_HUMAN
θ value	0.125558 (rank : 176)	NC score	-0.000533 (rank : 649)
Query Neighborhood Hits	375	Target Neighborhood Hits	1804	Shared Neighborhood Hits	83
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CN004_MOUSE
θ value	0.163984 (rank : 177)	NC score	0.026760 (rank : 529)
Query Neighborhood Hits	375	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

MDC1_HUMAN
θ value	0.163984 (rank : 178)	NC score	0.031382 (rank : 519)
Query Neighborhood Hits	375	Target Neighborhood Hits	1446	Shared Neighborhood Hits	90
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYO15_HUMAN
θ value	0.163984 (rank : 179)	NC score	0.011254 (rank : 595)
Query Neighborhood Hits	375	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NACAM_MOUSE
θ value	0.163984 (rank : 180)	NC score	0.040564 (rank : 498)
Query Neighborhood Hits	375	Target Neighborhood Hits	1866	Shared Neighborhood Hits	127
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RSPO3_HUMAN
θ value	0.163984 (rank : 181)	NC score	0.128451 (rank : 165)
Query Neighborhood Hits	375	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

SPON2_MOUSE
θ value	0.163984 (rank : 182)	NC score	0.161010 (rank : 152)
Query Neighborhood Hits	375	Target Neighborhood Hits	42	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

CD2_HUMAN
θ value	0.21417 (rank : 183)	NC score	0.030347 (rank : 520)
Query Neighborhood Hits	375	Target Neighborhood Hits	504	Shared Neighborhood Hits	42
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

FA47B_HUMAN
θ value	0.21417 (rank : 184)	NC score	0.038332 (rank : 501)
Query Neighborhood Hits	375	Target Neighborhood Hits	431	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FZD5_HUMAN
θ value	0.21417 (rank : 185)	NC score	0.053857 (rank : 434)
Query Neighborhood Hits	375	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

NOTC2_HUMAN
θ value	0.21417 (rank : 186)	NC score	0.093558 (rank : 247)
Query Neighborhood Hits	375	Target Neighborhood Hits	1113	Shared Neighborhood Hits	102
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PCLO_MOUSE
θ value	0.21417 (rank : 187)	NC score	0.034712 (rank : 510)
Query Neighborhood Hits	375	Target Neighborhood Hits	2275	Shared Neighborhood Hits	136
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RGS3_HUMAN
θ value	0.21417 (rank : 188)	NC score	0.024093 (rank : 538)
Query Neighborhood Hits	375	Target Neighborhood Hits	1375	Shared Neighborhood Hits	82
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CBL_MOUSE
θ value	0.279714 (rank : 189)	NC score	0.013342 (rank : 585)
Query Neighborhood Hits	375	Target Neighborhood Hits	426	Shared Neighborhood Hits	33
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

GAB1_HUMAN
θ value	0.279714 (rank : 190)	NC score	0.032617 (rank : 514)
Query Neighborhood Hits	375	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MAGE1_HUMAN
θ value	0.279714 (rank : 191)	NC score	0.027105 (rank : 528)
Query Neighborhood Hits	375	Target Neighborhood Hits	1389	Shared Neighborhood Hits	101
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NOTC3_HUMAN
θ value	0.279714 (rank : 192)	NC score	0.098112 (rank : 214)
Query Neighborhood Hits	375	Target Neighborhood Hits	1062	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PHC2_HUMAN
θ value	0.279714 (rank : 193)	NC score	0.023666 (rank : 541)
Query Neighborhood Hits	375	Target Neighborhood Hits	388	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

SSBP4_HUMAN
θ value	0.279714 (rank : 194)	NC score	0.016896 (rank : 576)
Query Neighborhood Hits	375	Target Neighborhood Hits	753	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

ANK2_HUMAN
θ value	0.365318 (rank : 195)	NC score	0.007712 (rank : 621)
Query Neighborhood Hits	375	Target Neighborhood Hits	1615	Shared Neighborhood Hits	80
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

FZD1_MOUSE
θ value	0.365318 (rank : 196)	NC score	0.059296 (rank : 390)
Query Neighborhood Hits	375	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD5_MOUSE
θ value	0.365318 (rank : 197)	NC score	0.052123 (rank : 460)
Query Neighborhood Hits	375	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

MLL3_MOUSE
θ value	0.365318 (rank : 198)	NC score	0.020196 (rank : 557)
Query Neighborhood Hits	375	Target Neighborhood Hits	1399	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

OR6X1_HUMAN
θ value	0.365318 (rank : 199)	NC score	-0.004904 (rank : 658)
Query Neighborhood Hits	375	Target Neighborhood Hits	771	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NH79, Q6IFA0	Gene names	OR6X1
Domain Architecture
Description	Olfactory receptor 6X1 (Olfactory receptor OR11-270).

RSPO1_MOUSE
θ value	0.365318 (rank : 200)	NC score	0.136812 (rank : 160)
Query Neighborhood Hits	375	Target Neighborhood Hits	85	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

SPR1A_MOUSE
θ value	0.365318 (rank : 201)	NC score	0.023154 (rank : 546)
Query Neighborhood Hits	375	Target Neighborhood Hits	343	Shared Neighborhood Hits	36
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

CBP_MOUSE
θ value	0.47712 (rank : 202)	NC score	0.031415 (rank : 518)
Query Neighborhood Hits	375	Target Neighborhood Hits	1051	Shared Neighborhood Hits	98
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

FOXN1_MOUSE
θ value	0.47712 (rank : 203)	NC score	0.010700 (rank : 598)
Query Neighborhood Hits	375	Target Neighborhood Hits	300	Shared Neighborhood Hits	22
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

NOV_HUMAN
θ value	0.47712 (rank : 204)	NC score	0.093622 (rank : 246)
Query Neighborhood Hits	375	Target Neighborhood Hits	128	Shared Neighborhood Hits	49
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

TENX_HUMAN
θ value	0.47712 (rank : 205)	NC score	0.074300 (rank : 315)
Query Neighborhood Hits	375	Target Neighborhood Hits	789	Shared Neighborhood Hits	84
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TXLNB_HUMAN
θ value	0.47712 (rank : 206)	NC score	0.004146 (rank : 635)
Query Neighborhood Hits	375	Target Neighborhood Hits	912	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

GAK5_HUMAN
θ value	0.62314 (rank : 207)	NC score	0.025345 (rank : 531)
Query Neighborhood Hits	375	Target Neighborhood Hits	429	Shared Neighborhood Hits	43
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	0.62314 (rank : 208)	NC score	0.024984 (rank : 532)
Query Neighborhood Hits	375	Target Neighborhood Hits	392	Shared Neighborhood Hits	42
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

MEGF6_HUMAN
θ value	0.62314 (rank : 209)	NC score	0.109556 (rank : 183)
Query Neighborhood Hits	375	Target Neighborhood Hits	671	Shared Neighborhood Hits	84
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

PI5PA_HUMAN
θ value	0.62314 (rank : 210)	NC score	0.030027 (rank : 521)
Query Neighborhood Hits	375	Target Neighborhood Hits	749	Shared Neighborhood Hits	80
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PSL1_HUMAN
θ value	0.62314 (rank : 211)	NC score	0.019789 (rank : 562)
Query Neighborhood Hits	375	Target Neighborhood Hits	650	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RSPO2_MOUSE
θ value	0.62314 (rank : 212)	NC score	0.079598 (rank : 301)
Query Neighborhood Hits	375	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

SPR1B_MOUSE
θ value	0.62314 (rank : 213)	NC score	0.021399 (rank : 551)
Query Neighborhood Hits	375	Target Neighborhood Hits	395	Shared Neighborhood Hits	41
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

BSN_MOUSE
θ value	0.813845 (rank : 214)	NC score	0.034558 (rank : 511)
Query Neighborhood Hits	375	Target Neighborhood Hits	2057	Shared Neighborhood Hits	130
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

FOXN1_HUMAN
θ value	0.813845 (rank : 215)	NC score	0.012674 (rank : 590)
Query Neighborhood Hits	375	Target Neighborhood Hits	377	Shared Neighborhood Hits	30
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

NFH_MOUSE
θ value	0.813845 (rank : 216)	NC score	0.006342 (rank : 625)
Query Neighborhood Hits	375	Target Neighborhood Hits	2247	Shared Neighborhood Hits	95
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

O10J6_HUMAN
θ value	0.813845 (rank : 217)	NC score	-0.002739 (rank : 653)
Query Neighborhood Hits	375	Target Neighborhood Hits	732	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NGY7, Q96R55	Gene names	OR10J6
Domain Architecture
Description	Olfactory receptor 10J6.

SAPS1_HUMAN
θ value	0.813845 (rank : 218)	NC score	0.019799 (rank : 561)
Query Neighborhood Hits	375	Target Neighborhood Hits	704	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEPT9_HUMAN
θ value	0.813845 (rank : 219)	NC score	0.013604 (rank : 582)
Query Neighborhood Hits	375	Target Neighborhood Hits	706	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ARMX2_MOUSE
θ value	1.06291 (rank : 220)	NC score	0.019873 (rank : 560)
Query Neighborhood Hits	375	Target Neighborhood Hits	349	Shared Neighborhood Hits	38
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

FOXH1_HUMAN
θ value	1.06291 (rank : 221)	NC score	0.008074 (rank : 615)
Query Neighborhood Hits	375	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

HGS_HUMAN
θ value	1.06291 (rank : 222)	NC score	0.010148 (rank : 602)
Query Neighborhood Hits	375	Target Neighborhood Hits	517	Shared Neighborhood Hits	31
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

OR4D1_HUMAN
θ value	1.06291 (rank : 223)	NC score	-0.005182 (rank : 659)
Query Neighborhood Hits	375	Target Neighborhood Hits	804	Shared Neighborhood Hits	11
SwissProt Accessions	Q15615, Q8NGB1, Q96R76	Gene names	OR4D1, OR4D3
Domain Architecture
Description	Olfactory receptor 4D1 (Olfactory receptor TPCR16).

PERF_HUMAN
θ value	1.06291 (rank : 224)	NC score	0.054702 (rank : 424)
Query Neighborhood Hits	375	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

RBBP6_HUMAN
θ value	1.06291 (rank : 225)	NC score	0.008661 (rank : 609)
Query Neighborhood Hits	375	Target Neighborhood Hits	1135	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SON_MOUSE
θ value	1.06291 (rank : 226)	NC score	0.038192 (rank : 503)
Query Neighborhood Hits	375	Target Neighborhood Hits	957	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CAC1G_HUMAN
θ value	1.38821 (rank : 227)	NC score	0.006753 (rank : 624)
Query Neighborhood Hits	375	Target Neighborhood Hits	587	Shared Neighborhood Hits	48
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CD248_MOUSE
θ value	1.38821 (rank : 228)	NC score	0.070837 (rank : 327)
Query Neighborhood Hits	375	Target Neighborhood Hits	578	Shared Neighborhood Hits	73
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CO9_MOUSE
θ value	1.38821 (rank : 229)	NC score	0.100797 (rank : 199)
Query Neighborhood Hits	375	Target Neighborhood Hits	153	Shared Neighborhood Hits	38
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

E2F5_HUMAN
θ value	1.38821 (rank : 230)	NC score	0.013656 (rank : 581)
Query Neighborhood Hits	375	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

FA47A_HUMAN
θ value	1.38821 (rank : 231)	NC score	0.038166 (rank : 504)
Query Neighborhood Hits	375	Target Neighborhood Hits	451	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

GAK11_HUMAN
θ value	1.38821 (rank : 232)	NC score	0.023565 (rank : 542)
Query Neighborhood Hits	375	Target Neighborhood Hits	409	Shared Neighborhood Hits	43
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	1.38821 (rank : 233)	NC score	0.023250 (rank : 544)
Query Neighborhood Hits	375	Target Neighborhood Hits	374	Shared Neighborhood Hits	43
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
θ value	1.38821 (rank : 234)	NC score	0.022309 (rank : 549)
Query Neighborhood Hits	375	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	1.38821 (rank : 235)	NC score	0.023168 (rank : 545)
Query Neighborhood Hits	375	Target Neighborhood Hits	406	Shared Neighborhood Hits	42
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	1.38821 (rank : 236)	NC score	0.024169 (rank : 536)
Query Neighborhood Hits	375	Target Neighborhood Hits	415	Shared Neighborhood Hits	44
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HAPIP_HUMAN
θ value	1.38821 (rank : 237)	NC score	0.005894 (rank : 627)
Query Neighborhood Hits	375	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

RPGF1_HUMAN
θ value	1.38821 (rank : 238)	NC score	0.007983 (rank : 616)
Query Neighborhood Hits	375	Target Neighborhood Hits	262	Shared Neighborhood Hits	19
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

RSPO2_HUMAN
θ value	1.38821 (rank : 239)	NC score	0.086187 (rank : 277)
Query Neighborhood Hits	375	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RX_MOUSE
θ value	1.38821 (rank : 240)	NC score	-0.001119 (rank : 650)
Query Neighborhood Hits	375	Target Neighborhood Hits	429	Shared Neighborhood Hits	19
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

TIE1_MOUSE
θ value	1.38821 (rank : 241)	NC score	0.008232 (rank : 614)
Query Neighborhood Hits	375	Target Neighborhood Hits	1266	Shared Neighborhood Hits	50
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

BCL7C_MOUSE
θ value	1.81305 (rank : 242)	NC score	0.020473 (rank : 554)
Query Neighborhood Hits	375	Target Neighborhood Hits	170	Shared Neighborhood Hits	25
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

DKK3_MOUSE
θ value	1.81305 (rank : 243)	NC score	0.020205 (rank : 556)
Query Neighborhood Hits	375	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

EDD1_HUMAN
θ value	1.81305 (rank : 244)	NC score	0.008950 (rank : 607)
Query Neighborhood Hits	375	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

ERBB2_HUMAN
θ value	1.81305 (rank : 245)	NC score	-0.004184 (rank : 657)
Query Neighborhood Hits	375	Target Neighborhood Hits	1073	Shared Neighborhood Hits	39
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

INP5E_HUMAN
θ value	1.81305 (rank : 246)	NC score	0.019141 (rank : 564)
Query Neighborhood Hits	375	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

LSD1_HUMAN
θ value	1.81305 (rank : 247)	NC score	0.012945 (rank : 589)
Query Neighborhood Hits	375	Target Neighborhood Hits	455	Shared Neighborhood Hits	26
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MEGF9_MOUSE
θ value	1.81305 (rank : 248)	NC score	0.066482 (rank : 349)
Query Neighborhood Hits	375	Target Neighborhood Hits	896	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NADAP_HUMAN
θ value	1.81305 (rank : 249)	NC score	0.013238 (rank : 586)
Query Neighborhood Hits	375	Target Neighborhood Hits	208	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

NOV_MOUSE
θ value	1.81305 (rank : 250)	NC score	0.093332 (rank : 248)
Query Neighborhood Hits	375	Target Neighborhood Hits	130	Shared Neighborhood Hits	53
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

PRP6_HUMAN
θ value	1.81305 (rank : 251)	NC score	0.020135 (rank : 559)
Query Neighborhood Hits	375	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	O94906, O95109, Q5VXS5, Q9H3Z1, Q9H4T9, Q9H4U8, Q9NTE6	Gene names	PRPF6, C20orf14
Domain Architecture
Description	Pre-mRNA-processing factor 6 homolog (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein).

PRP6_MOUSE
θ value	1.81305 (rank : 252)	NC score	0.020171 (rank : 558)
Query Neighborhood Hits	375	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YR7, Q8CIK9, Q8R3M8, Q99JN1, Q9CSZ0	Gene names	Prpf6
Domain Architecture
Description	Pre-mRNA-processing factor 6 homolog (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein).

RP3A_MOUSE
θ value	1.81305 (rank : 253)	NC score	0.008398 (rank : 612)
Query Neighborhood Hits	375	Target Neighborhood Hits	510	Shared Neighborhood Hits	48
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TENA_HUMAN
θ value	1.81305 (rank : 254)	NC score	0.052470 (rank : 454)
Query Neighborhood Hits	375	Target Neighborhood Hits	631	Shared Neighborhood Hits	56
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TTLL5_MOUSE
θ value	1.81305 (rank : 255)	NC score	0.008606 (rank : 610)
Query Neighborhood Hits	375	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

WISP2_MOUSE
θ value	1.81305 (rank : 256)	NC score	0.115844 (rank : 174)
Query Neighborhood Hits	375	Target Neighborhood Hits	129	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

BRD3_MOUSE
θ value	2.36792 (rank : 257)	NC score	0.007634 (rank : 623)
Query Neighborhood Hits	375	Target Neighborhood Hits	402	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

CSKI1_HUMAN
θ value	2.36792 (rank : 258)	NC score	0.015374 (rank : 579)
Query Neighborhood Hits	375	Target Neighborhood Hits	997	Shared Neighborhood Hits	97
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CT012_MOUSE
θ value	2.36792 (rank : 259)	NC score	0.013530 (rank : 584)
Query Neighborhood Hits	375	Target Neighborhood Hits	229	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

EDD1_MOUSE
θ value	2.36792 (rank : 260)	NC score	0.008310 (rank : 613)
Query Neighborhood Hits	375	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

FUT4_MOUSE
θ value	2.36792 (rank : 261)	NC score	0.023872 (rank : 540)
Query Neighborhood Hits	375	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q11127	Gene names	Fut4, Elft
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 4) (FUCT-IV) (Fuc-TIV).

FZD7_HUMAN
θ value	2.36792 (rank : 262)	NC score	0.041416 (rank : 497)
Query Neighborhood Hits	375	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD9_MOUSE
θ value	2.36792 (rank : 263)	NC score	0.048060 (rank : 488)
Query Neighborhood Hits	375	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

IF4G1_MOUSE
θ value	2.36792 (rank : 264)	NC score	0.027543 (rank : 526)
Query Neighborhood Hits	375	Target Neighborhood Hits	534	Shared Neighborhood Hits	55
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K1802_HUMAN
θ value	2.36792 (rank : 265)	NC score	0.019446 (rank : 563)
Query Neighborhood Hits	375	Target Neighborhood Hits	1378	Shared Neighborhood Hits	102
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1849_MOUSE
θ value	2.36792 (rank : 266)	NC score	0.003741 (rank : 638)
Query Neighborhood Hits	375	Target Neighborhood Hits	335	Shared Neighborhood Hits	10
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

KR412_HUMAN
θ value	2.36792 (rank : 267)	NC score	0.060474 (rank : 377)
Query Neighborhood Hits	375	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

NCOA6_HUMAN
θ value	2.36792 (rank : 268)	NC score	0.023272 (rank : 543)
Query Neighborhood Hits	375	Target Neighborhood Hits	1202	Shared Neighborhood Hits	98
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NOTC3_MOUSE
θ value	2.36792 (rank : 269)	NC score	0.098924 (rank : 207)
Query Neighborhood Hits	375	Target Neighborhood Hits	975	Shared Neighborhood Hits	105
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RSPO4_MOUSE
θ value	2.36792 (rank : 270)	NC score	0.117020 (rank : 171)
Query Neighborhood Hits	375	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RUSC2_MOUSE
θ value	2.36792 (rank : 271)	NC score	0.017633 (rank : 571)
Query Neighborhood Hits	375	Target Neighborhood Hits	305	Shared Neighborhood Hits	32
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SYNJ1_HUMAN
θ value	2.36792 (rank : 272)	NC score	0.031855 (rank : 517)
Query Neighborhood Hits	375	Target Neighborhood Hits	498	Shared Neighborhood Hits	91
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TMEPA_MOUSE
θ value	2.36792 (rank : 273)	NC score	0.013191 (rank : 587)
Query Neighborhood Hits	375	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

UB7I1_MOUSE
θ value	2.36792 (rank : 274)	NC score	0.010362 (rank : 600)
Query Neighborhood Hits	375	Target Neighborhood Hits	206	Shared Neighborhood Hits	18
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

ADA12_MOUSE
θ value	3.0926 (rank : 275)	NC score	0.098120 (rank : 213)
Query Neighborhood Hits	375	Target Neighborhood Hits	474	Shared Neighborhood Hits	80
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

DLL1_HUMAN
θ value	3.0926 (rank : 276)	NC score	0.103728 (rank : 190)
Query Neighborhood Hits	375	Target Neighborhood Hits	455	Shared Neighborhood Hits	59
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

EFS_HUMAN
θ value	3.0926 (rank : 277)	NC score	0.018367 (rank : 566)
Query Neighborhood Hits	375	Target Neighborhood Hits	348	Shared Neighborhood Hits	49
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

FZD1_HUMAN
θ value	3.0926 (rank : 278)	NC score	0.049370 (rank : 487)
Query Neighborhood Hits	375	Target Neighborhood Hits	62	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

HCLS1_HUMAN
θ value	3.0926 (rank : 279)	NC score	0.004183 (rank : 633)
Query Neighborhood Hits	375	Target Neighborhood Hits	358	Shared Neighborhood Hits	25
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HPS4_MOUSE
θ value	3.0926 (rank : 280)	NC score	0.012292 (rank : 592)
Query Neighborhood Hits	375	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

IL3B2_MOUSE
θ value	3.0926 (rank : 281)	NC score	0.024869 (rank : 533)
Query Neighborhood Hits	375	Target Neighborhood Hits	372	Shared Neighborhood Hits	42
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL3RB_MOUSE
θ value	3.0926 (rank : 282)	NC score	0.024203 (rank : 535)
Query Neighborhood Hits	375	Target Neighborhood Hits	355	Shared Neighborhood Hits	37
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

LAMA3_MOUSE
θ value	3.0926 (rank : 283)	NC score	0.046582 (rank : 490)
Query Neighborhood Hits	375	Target Neighborhood Hits	859	Shared Neighborhood Hits	55
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA5_HUMAN
θ value	3.0926 (rank : 284)	NC score	0.061433 (rank : 369)
Query Neighborhood Hits	375	Target Neighborhood Hits	976	Shared Neighborhood Hits	68
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MAP1A_HUMAN
θ value	3.0926 (rank : 285)	NC score	0.010350 (rank : 601)
Query Neighborhood Hits	375	Target Neighborhood Hits	1626	Shared Neighborhood Hits	85
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MINT_MOUSE
θ value	3.0926 (rank : 286)	NC score	0.017964 (rank : 569)
Query Neighborhood Hits	375	Target Neighborhood Hits	1514	Shared Neighborhood Hits	92
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MKL2_MOUSE
θ value	3.0926 (rank : 287)	NC score	0.021311 (rank : 552)
Query Neighborhood Hits	375	Target Neighborhood Hits	269	Shared Neighborhood Hits	29
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

OBSCN_HUMAN
θ value	3.0926 (rank : 288)	NC score	0.012989 (rank : 588)
Query Neighborhood Hits	375	Target Neighborhood Hits	1931	Shared Neighborhood Hits	90
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OR4B1_HUMAN
θ value	3.0926 (rank : 289)	NC score	-0.001254 (rank : 651)
Query Neighborhood Hits	375	Target Neighborhood Hits	652	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NGF8, Q6IF75, Q96R64	Gene names	OR4B1
Domain Architecture
Description	Olfactory receptor 4B1 (OST208) (Olfactory receptor OR11-106).

PSMF1_MOUSE
θ value	3.0926 (rank : 290)	NC score	0.015621 (rank : 578)
Query Neighborhood Hits	375	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

SC24A_MOUSE
θ value	3.0926 (rank : 291)	NC score	0.021049 (rank : 553)
Query Neighborhood Hits	375	Target Neighborhood Hits	394	Shared Neighborhood Hits	56
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SSH1_HUMAN
θ value	3.0926 (rank : 292)	NC score	0.004033 (rank : 637)
Query Neighborhood Hits	375	Target Neighborhood Hits	164	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

TARSH_HUMAN
θ value	3.0926 (rank : 293)	NC score	0.035538 (rank : 506)
Query Neighborhood Hits	375	Target Neighborhood Hits	768	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TOP1_MOUSE
θ value	3.0926 (rank : 294)	NC score	0.008704 (rank : 608)
Query Neighborhood Hits	375	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

ZN385_HUMAN
θ value	3.0926 (rank : 295)	NC score	0.029814 (rank : 522)
Query Neighborhood Hits	375	Target Neighborhood Hits	614	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZN516_MOUSE
θ value	3.0926 (rank : 296)	NC score	-0.006724 (rank : 661)
Query Neighborhood Hits	375	Target Neighborhood Hits	1197	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

AL2S4_MOUSE
θ value	4.03905 (rank : 297)	NC score	0.014597 (rank : 580)
Query Neighborhood Hits	375	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

CEP35_HUMAN
θ value	4.03905 (rank : 298)	NC score	0.001539 (rank : 644)
Query Neighborhood Hits	375	Target Neighborhood Hits	811	Shared Neighborhood Hits	24
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CJ108_HUMAN
θ value	4.03905 (rank : 299)	NC score	0.022485 (rank : 548)
Query Neighborhood Hits	375	Target Neighborhood Hits	165	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CO6A3_HUMAN
θ value	4.03905 (rank : 300)	NC score	0.004490 (rank : 631)
Query Neighborhood Hits	375	Target Neighborhood Hits	317	Shared Neighborhood Hits	32
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

CSKI1_MOUSE
θ value	4.03905 (rank : 301)	NC score	0.013558 (rank : 583)
Query Neighborhood Hits	375	Target Neighborhood Hits	1031	Shared Neighborhood Hits	94
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CUBN_HUMAN
θ value	4.03905 (rank : 302)	NC score	0.090415 (rank : 263)
Query Neighborhood Hits	375	Target Neighborhood Hits	482	Shared Neighborhood Hits	53
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

ETV3_HUMAN
θ value	4.03905 (rank : 303)	NC score	0.004267 (rank : 632)
Query Neighborhood Hits	375	Target Neighborhood Hits	312	Shared Neighborhood Hits	32
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FZD7_MOUSE
θ value	4.03905 (rank : 304)	NC score	0.043813 (rank : 493)
Query Neighborhood Hits	375	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD9_HUMAN
θ value	4.03905 (rank : 305)	NC score	0.045563 (rank : 491)
Query Neighborhood Hits	375	Target Neighborhood Hits	63	Shared Neighborhood Hits	28
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

GNAS1_MOUSE
θ value	4.03905 (rank : 306)	NC score	0.017872 (rank : 570)
Query Neighborhood Hits	375	Target Neighborhood Hits	651	Shared Neighborhood Hits	63
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

IGF1R_HUMAN
θ value	4.03905 (rank : 307)	NC score	-0.001882 (rank : 652)
Query Neighborhood Hits	375	Target Neighborhood Hits	977	Shared Neighborhood Hits	40
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

JADE2_MOUSE
θ value	4.03905 (rank : 308)	NC score	0.006234 (rank : 626)
Query Neighborhood Hits	375	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

K1802_MOUSE
θ value	4.03905 (rank : 309)	NC score	0.010876 (rank : 596)
Query Neighborhood Hits	375	Target Neighborhood Hits	1596	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KRA42_HUMAN
θ value	4.03905 (rank : 310)	NC score	0.039338 (rank : 500)
Query Neighborhood Hits	375	Target Neighborhood Hits	149	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

PKN3_MOUSE
θ value	4.03905 (rank : 311)	NC score	-0.008329 (rank : 665)
Query Neighborhood Hits	375	Target Neighborhood Hits	1009	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

TCF7_MOUSE
θ value	4.03905 (rank : 312)	NC score	0.004051 (rank : 636)
Query Neighborhood Hits	375	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TIE1_HUMAN
θ value	4.03905 (rank : 313)	NC score	0.007774 (rank : 618)
Query Neighborhood Hits	375	Target Neighborhood Hits	1241	Shared Neighborhood Hits	48
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TXND2_HUMAN
θ value	4.03905 (rank : 314)	NC score	0.017272 (rank : 574)
Query Neighborhood Hits	375	Target Neighborhood Hits	793	Shared Neighborhood Hits	47
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

VWF_HUMAN
θ value	4.03905 (rank : 315)	NC score	0.059993 (rank : 381)
Query Neighborhood Hits	375	Target Neighborhood Hits	396	Shared Neighborhood Hits	57
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

AATK_HUMAN
θ value	5.27518 (rank : 316)	NC score	-0.003459 (rank : 654)
Query Neighborhood Hits	375	Target Neighborhood Hits	1243	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

BKRB2_HUMAN
θ value	5.27518 (rank : 317)	NC score	-0.003918 (rank : 656)
Query Neighborhood Hits	375	Target Neighborhood Hits	533	Shared Neighborhood Hits	9
SwissProt Accessions	P30411	Gene names	BDKRB2, BKR2
Domain Architecture
Description	B2 bradykinin receptor (BK-2 receptor) (B2R).

CLMN_MOUSE
θ value	5.27518 (rank : 318)	NC score	0.002409 (rank : 639)
Query Neighborhood Hits	375	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

DUET_HUMAN
θ value	5.27518 (rank : 319)	NC score	-0.003706 (rank : 655)
Query Neighborhood Hits	375	Target Neighborhood Hits	1220	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ERRFI_HUMAN
θ value	5.27518 (rank : 320)	NC score	0.007703 (rank : 622)
Query Neighborhood Hits	375	Target Neighborhood Hits	72	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

LAD1_MOUSE
θ value	5.27518 (rank : 321)	NC score	0.016133 (rank : 577)
Query Neighborhood Hits	375	Target Neighborhood Hits	391	Shared Neighborhood Hits	33
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MDC1_MOUSE
θ value	5.27518 (rank : 322)	NC score	0.024082 (rank : 539)
Query Neighborhood Hits	375	Target Neighborhood Hits	998	Shared Neighborhood Hits	80
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MLL3_HUMAN
θ value	5.27518 (rank : 323)	NC score	0.022792 (rank : 547)
Query Neighborhood Hits	375	Target Neighborhood Hits	1644	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NCOA6_MOUSE
θ value	5.27518 (rank : 324)	NC score	0.024097 (rank : 537)
Query Neighborhood Hits	375	Target Neighborhood Hits	1076	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

OBF1_HUMAN
θ value	5.27518 (rank : 325)	NC score	0.010023 (rank : 603)
Query Neighborhood Hits	375	Target Neighborhood Hits	203	Shared Neighborhood Hits	24
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

PKHA6_HUMAN
θ value	5.27518 (rank : 326)	NC score	0.005802 (rank : 628)
Query Neighborhood Hits	375	Target Neighborhood Hits	556	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PPRB_HUMAN
θ value	5.27518 (rank : 327)	NC score	0.021559 (rank : 550)
Query Neighborhood Hits	375	Target Neighborhood Hits	311	Shared Neighborhood Hits	33
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PYR1_HUMAN
θ value	5.27518 (rank : 328)	NC score	0.004163 (rank : 634)
Query Neighborhood Hits	375	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

RC3H1_HUMAN
θ value	5.27518 (rank : 329)	NC score	0.004798 (rank : 630)
Query Neighborhood Hits	375	Target Neighborhood Hits	433	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RECQ4_MOUSE
θ value	5.27518 (rank : 330)	NC score	0.002065 (rank : 640)
Query Neighborhood Hits	375	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

SC6A3_HUMAN
θ value	5.27518 (rank : 331)	NC score	0.001900 (rank : 641)
Query Neighborhood Hits	375	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q01959, Q14996	Gene names	SLC6A3, DAT1
Domain Architecture
Description	Sodium-dependent dopamine transporter (DA transporter) (DAT).

SC6A3_MOUSE
θ value	5.27518 (rank : 332)	NC score	0.001870 (rank : 643)
Query Neighborhood Hits	375	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q61327, Q60719, Q9R1I2	Gene names	Slc6a3, Dat, Dat1
Domain Architecture
Description	Sodium-dependent dopamine transporter (DA transporter) (DAT).

SMAL1_MOUSE
θ value	5.27518 (rank : 333)	NC score	0.001870 (rank : 642)
Query Neighborhood Hits	375	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SPEG_MOUSE
θ value	5.27518 (rank : 334)	NC score	0.012628 (rank : 591)
Query Neighborhood Hits	375	Target Neighborhood Hits	1959	Shared Neighborhood Hits	122
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYNPO_HUMAN
θ value	5.27518 (rank : 335)	NC score	0.012083 (rank : 593)
Query Neighborhood Hits	375	Target Neighborhood Hits	281	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TMM24_MOUSE
θ value	5.27518 (rank : 336)	NC score	0.008993 (rank : 606)
Query Neighborhood Hits	375	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

WISP2_HUMAN
θ value	5.27518 (rank : 337)	NC score	0.110943 (rank : 179)
Query Neighborhood Hits	375	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

ACM3_HUMAN
θ value	6.88961 (rank : 338)	NC score	-0.008204 (rank : 664)
Query Neighborhood Hits	375	Target Neighborhood Hits	931	Shared Neighborhood Hits	10
SwissProt Accessions	P20309, Q4QRI3, Q5VXY2, Q9HB60	Gene names	CHRM3
Domain Architecture
Description	Muscarinic acetylcholine receptor M3.

BCL9_HUMAN
θ value	6.88961 (rank : 339)	NC score	0.020458 (rank : 555)
Query Neighborhood Hits	375	Target Neighborhood Hits	1008	Shared Neighborhood Hits	90
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	6.88961 (rank : 340)	NC score	0.024571 (rank : 534)
Query Neighborhood Hits	375	Target Neighborhood Hits	770	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CPSF7_HUMAN
θ value	6.88961 (rank : 341)	NC score	0.018256 (rank : 568)
Query Neighborhood Hits	375	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

CPSF7_MOUSE
θ value	6.88961 (rank : 342)	NC score	0.018359 (rank : 567)
Query Neighborhood Hits	375	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

DZIP1_MOUSE
θ value	6.88961 (rank : 343)	NC score	-0.000458 (rank : 648)
Query Neighborhood Hits	375	Target Neighborhood Hits	530	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

GAK7_HUMAN
θ value	6.88961 (rank : 344)	NC score	0.017517 (rank : 573)
Query Neighborhood Hits	375	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

HHIP_HUMAN
θ value	6.88961 (rank : 345)	NC score	0.043462 (rank : 494)
Query Neighborhood Hits	375	Target Neighborhood Hits	249	Shared Neighborhood Hits	33
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

K1543_HUMAN
θ value	6.88961 (rank : 346)	NC score	0.027540 (rank : 527)
Query Neighborhood Hits	375	Target Neighborhood Hits	435	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KR414_HUMAN
θ value	6.88961 (rank : 347)	NC score	0.080976 (rank : 297)
Query Neighborhood Hits	375	Target Neighborhood Hits	199	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LIMD1_MOUSE
θ value	6.88961 (rank : 348)	NC score	0.000166 (rank : 646)
Query Neighborhood Hits	375	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MLL2_HUMAN
θ value	6.88961 (rank : 349)	NC score	0.034229 (rank : 512)
Query Neighborhood Hits	375	Target Neighborhood Hits	1788	Shared Neighborhood Hits	139
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OR6K2_HUMAN
θ value	6.88961 (rank : 350)	NC score	-0.007306 (rank : 663)
Query Neighborhood Hits	375	Target Neighborhood Hits	711	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NGY2	Gene names	OR6K2
Domain Architecture
Description	Olfactory receptor 6K2.

PAK4_HUMAN
θ value	6.88961 (rank : 351)	NC score	-0.008573 (rank : 666)
Query Neighborhood Hits	375	Target Neighborhood Hits	924	Shared Neighborhood Hits	37
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

SPEG_HUMAN
θ value	6.88961 (rank : 352)	NC score	0.010495 (rank : 599)
Query Neighborhood Hits	375	Target Neighborhood Hits	1762	Shared Neighborhood Hits	120
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TENA_MOUSE
θ value	6.88961 (rank : 353)	NC score	0.047103 (rank : 489)
Query Neighborhood Hits	375	Target Neighborhood Hits	596	Shared Neighborhood Hits	51
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

UNG_HUMAN
θ value	6.88961 (rank : 354)	NC score	0.017624 (rank : 572)
Query Neighborhood Hits	375	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P13051, O00637, O00719, Q93028	Gene names	UNG, DGU, UNG15
Domain Architecture
Description	Uracil-DNA glycosylase (EC 3.2.2.-) (UDG).

ZIM10_HUMAN
θ value	6.88961 (rank : 355)	NC score	0.008540 (rank : 611)
Query Neighborhood Hits	375	Target Neighborhood Hits	577	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_MOUSE
θ value	6.88961 (rank : 356)	NC score	0.009094 (rank : 605)
Query Neighborhood Hits	375	Target Neighborhood Hits	430	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

BAT3_HUMAN
θ value	8.99809 (rank : 357)	NC score	0.028737 (rank : 524)
Query Neighborhood Hits	375	Target Neighborhood Hits	490	Shared Neighborhood Hits	63
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CN092_MOUSE
θ value	8.99809 (rank : 358)	NC score	0.007729 (rank : 620)
Query Neighborhood Hits	375	Target Neighborhood Hits	206	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CS007_MOUSE
θ value	8.99809 (rank : 359)	NC score	0.025686 (rank : 530)
Query Neighborhood Hits	375	Target Neighborhood Hits	464	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CYR61_HUMAN
θ value	8.99809 (rank : 360)	NC score	0.100116 (rank : 202)
Query Neighborhood Hits	375	Target Neighborhood Hits	159	Shared Neighborhood Hits	62
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

ECM1_HUMAN
θ value	8.99809 (rank : 361)	NC score	0.010786 (rank : 597)
Query Neighborhood Hits	375	Target Neighborhood Hits	182	Shared Neighborhood Hits	28
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

FMN2_HUMAN
θ value	8.99809 (rank : 362)	NC score	0.034901 (rank : 508)
Query Neighborhood Hits	375	Target Neighborhood Hits	484	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GCH1_HUMAN
θ value	8.99809 (rank : 363)	NC score	0.009247 (rank : 604)
Query Neighborhood Hits	375	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

IF4B_MOUSE
θ value	8.99809 (rank : 364)	NC score	0.007746 (rank : 619)
Query Neighborhood Hits	375	Target Neighborhood Hits	368	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

LATS2_HUMAN
θ value	8.99809 (rank : 365)	NC score	-0.006943 (rank : 662)
Query Neighborhood Hits	375	Target Neighborhood Hits	884	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

MAGD1_HUMAN
θ value	8.99809 (rank : 366)	NC score	0.005078 (rank : 629)
Query Neighborhood Hits	375	Target Neighborhood Hits	130	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

MISS_MOUSE
θ value	8.99809 (rank : 367)	NC score	0.027547 (rank : 525)
Query Neighborhood Hits	375	Target Neighborhood Hits	444	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

NUMBL_HUMAN
θ value	8.99809 (rank : 368)	NC score	0.007948 (rank : 617)
Query Neighborhood Hits	375	Target Neighborhood Hits	394	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

O10A4_HUMAN
θ value	8.99809 (rank : 369)	NC score	-0.005419 (rank : 660)
Query Neighborhood Hits	375	Target Neighborhood Hits	686	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H209, Q96R20	Gene names	OR10A4
Domain Architecture
Description	Olfactory receptor 10A4 (HP2) (Olfactory receptor-like protein JCG5).

PRAX_MOUSE
θ value	8.99809 (rank : 370)	NC score	0.017001 (rank : 575)
Query Neighborhood Hits	375	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SFR12_MOUSE
θ value	8.99809 (rank : 371)	NC score	0.000344 (rank : 645)
Query Neighborhood Hits	375	Target Neighborhood Hits	486	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

STAB1_HUMAN
θ value	8.99809 (rank : 372)	NC score	0.097303 (rank : 223)
Query Neighborhood Hits	375	Target Neighborhood Hits	546	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TAB3_MOUSE
θ value	8.99809 (rank : 373)	NC score	0.011340 (rank : 594)
Query Neighborhood Hits	375	Target Neighborhood Hits	273	Shared Neighborhood Hits	36
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TPO_MOUSE
θ value	8.99809 (rank : 374)	NC score	0.018669 (rank : 565)
Query Neighborhood Hits	375	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

ZN282_HUMAN
θ value	8.99809 (rank : 375)	NC score	-0.009812 (rank : 667)
Query Neighborhood Hits	375	Target Neighborhood Hits	796	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).

AD26A_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.068608 (rank : 340)
Query Neighborhood Hits	375	Target Neighborhood Hits	165	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA10_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.053525 (rank : 439)
Query Neighborhood Hits	375	Target Neighborhood Hits	189	Shared Neighborhood Hits	43
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.053275 (rank : 442)
Query Neighborhood Hits	375	Target Neighborhood Hits	194	Shared Neighborhood Hits	42
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA11_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.059607 (rank : 383)
Query Neighborhood Hits	375	Target Neighborhood Hits	259	Shared Neighborhood Hits	53
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.068944 (rank : 338)
Query Neighborhood Hits	375	Target Neighborhood Hits	263	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA12_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.098620 (rank : 209)
Query Neighborhood Hits	375	Target Neighborhood Hits	224	Shared Neighborhood Hits	53
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.092978 (rank : 249)
Query Neighborhood Hits	375	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.083502 (rank : 287)
Query Neighborhood Hits	375	Target Neighborhood Hits	324	Shared Neighborhood Hits	72
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.052446 (rank : 455)
Query Neighborhood Hits	375	Target Neighborhood Hits	223	Shared Neighborhood Hits	44
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.054421 (rank : 431)
Query Neighborhood Hits	375	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.051337 (rank : 472)
Query Neighborhood Hits	375	Target Neighborhood Hits	227	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA19_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.103110 (rank : 191)
Query Neighborhood Hits	375	Target Neighborhood Hits	381	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.110626 (rank : 180)
Query Neighborhood Hits	375	Target Neighborhood Hits	315	Shared Neighborhood Hits	74
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA20_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.052256 (rank : 458)
Query Neighborhood Hits	375	Target Neighborhood Hits	143	Shared Neighborhood Hits	40
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.069473 (rank : 333)
Query Neighborhood Hits	375	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.076978 (rank : 307)
Query Neighborhood Hits	375	Target Neighborhood Hits	172	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.076378 (rank : 309)
Query Neighborhood Hits	375	Target Neighborhood Hits	211	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.072947 (rank : 320)
Query Neighborhood Hits	375	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.071712 (rank : 326)
Query Neighborhood Hits	375	Target Neighborhood Hits	235	Shared Neighborhood Hits	49
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.075151 (rank : 314)
Query Neighborhood Hits	375	Target Neighborhood Hits	245	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.073521 (rank : 318)
Query Neighborhood Hits	375	Target Neighborhood Hits	230	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.069355 (rank : 334)
Query Neighborhood Hits	375	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.097487 (rank : 221)
Query Neighborhood Hits	375	Target Neighborhood Hits	244	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.100679 (rank : 200)
Query Neighborhood Hits	375	Target Neighborhood Hits	241	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA29_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.072280 (rank : 323)
Query Neighborhood Hits	375	Target Neighborhood Hits	247	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA32_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.054445 (rank : 430)
Query Neighborhood Hits	375	Target Neighborhood Hits	216	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.052770 (rank : 449)
Query Neighborhood Hits	375	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA33_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.098862 (rank : 208)
Query Neighborhood Hits	375	Target Neighborhood Hits	264	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.090008 (rank : 267)
Query Neighborhood Hits	375	Target Neighborhood Hits	231	Shared Neighborhood Hits	51
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.060492 (rank : 376)
Query Neighborhood Hits	375	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.087968 (rank : 274)
Query Neighborhood Hits	375	Target Neighborhood Hits	221	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.089775 (rank : 269)
Query Neighborhood Hits	375	Target Neighborhood Hits	200	Shared Neighborhood Hits	49
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM8_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.115272 (rank : 175)
Query Neighborhood Hits	375	Target Neighborhood Hits	327	Shared Neighborhood Hits	74
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.112283 (rank : 178)
Query Neighborhood Hits	375	Target Neighborhood Hits	326	Shared Neighborhood Hits	76
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.087435 (rank : 275)
Query Neighborhood Hits	375	Target Neighborhood Hits	243	Shared Neighborhood Hits	52
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.097294 (rank : 224)
Query Neighborhood Hits	375	Target Neighborhood Hits	325	Shared Neighborhood Hits	74
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADEC1_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.095301 (rank : 237)
Query Neighborhood Hits	375	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.077651 (rank : 304)
Query Neighborhood Hits	375	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADM1A_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.075697 (rank : 312)
Query Neighborhood Hits	375	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.077521 (rank : 306)
Query Neighborhood Hits	375	Target Neighborhood Hits	236	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

AGRIN_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.090336 (rank : 265)
Query Neighborhood Hits	375	Target Neighborhood Hits	582	Shared Neighborhood Hits	78
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

BMPER_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.060268 (rank : 379)
Query Neighborhood Hits	375	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.054818 (rank : 420)
Query Neighborhood Hits	375	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

C1QR1_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.108926 (rank : 185)
Query Neighborhood Hits	375	Target Neighborhood Hits	493	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.108762 (rank : 186)
Query Neighborhood Hits	375	Target Neighborhood Hits	342	Shared Neighborhood Hits	41
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CAD16_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.054651 (rank : 427)
Query Neighborhood Hits	375	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CAD16_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.054573 (rank : 429)
Query Neighborhood Hits	375	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CAD17_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.056341 (rank : 405)
Query Neighborhood Hits	375	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

CAD17_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.058359 (rank : 396)
Query Neighborhood Hits	375	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

CAD23_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.066662 (rank : 348)
Query Neighborhood Hits	375	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.067095 (rank : 347)
Query Neighborhood Hits	375	Target Neighborhood Hits	208	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CD248_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.062937 (rank : 362)
Query Neighborhood Hits	375	Target Neighborhood Hits	679	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CO9_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.084623 (rank : 283)
Query Neighborhood Hits	375	Target Neighborhood Hits	147	Shared Neighborhood Hits	30
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

COMP_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.150291 (rank : 157)
Query Neighborhood Hits	375	Target Neighborhood Hits	258	Shared Neighborhood Hits	33
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.156429 (rank : 155)
Query Neighborhood Hits	375	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.098079 (rank : 215)
Query Neighborhood Hits	375	Target Neighborhood Hits	441	Shared Neighborhood Hits	47
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.095419 (rank : 235)
Query Neighborhood Hits	375	Target Neighborhood Hits	524	Shared Neighborhood Hits	49
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.068954 (rank : 337)
Query Neighborhood Hits	375	Target Neighborhood Hits	362	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.121073 (rank : 169)
Query Neighborhood Hits	375	Target Neighborhood Hits	457	Shared Neighborhood Hits	57
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.119986 (rank : 170)
Query Neighborhood Hits	375	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.113357 (rank : 177)
Query Neighborhood Hits	375	Target Neighborhood Hits	453	Shared Neighborhood Hits	54
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSPG2_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.061849 (rank : 366)
Query Neighborhood Hits	375	Target Neighborhood Hits	681	Shared Neighborhood Hits	58
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.065329 (rank : 352)
Query Neighborhood Hits	375	Target Neighborhood Hits	711	Shared Neighborhood Hits	69
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.065288 (rank : 353)
Query Neighborhood Hits	375	Target Neighborhood Hits	676	Shared Neighborhood Hits	67
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.070528 (rank : 330)
Query Neighborhood Hits	375	Target Neighborhood Hits	657	Shared Neighborhood Hits	75
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CTGF_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.068384 (rank : 341)
Query Neighborhood Hits	375	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.069239 (rank : 336)
Query Neighborhood Hits	375	Target Neighborhood Hits	124	Shared Neighborhood Hits	51
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CU063_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.050087 (rank : 484)
Query Neighborhood Hits	375	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P58658, Q8IXZ0	Gene names	C21orf63
Domain Architecture
Description	Protein C21orf63 precursor (SUE21).

CUBN_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.097582 (rank : 218)
Query Neighborhood Hits	375	Target Neighborhood Hits	477	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CYR61_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.083905 (rank : 285)
Query Neighborhood Hits	375	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DLK_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.092697 (rank : 251)
Query Neighborhood Hits	375	Target Neighborhood Hits	401	Shared Neighborhood Hits	48
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.091883 (rank : 255)
Query Neighborhood Hits	375	Target Neighborhood Hits	374	Shared Neighborhood Hits	51
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.101574 (rank : 196)
Query Neighborhood Hits	375	Target Neighborhood Hits	456	Shared Neighborhood Hits	60
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.085638 (rank : 279)
Query Neighborhood Hits	375	Target Neighborhood Hits	419	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.089751 (rank : 270)
Query Neighborhood Hits	375	Target Neighborhood Hits	399	Shared Neighborhood Hits	53
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.097218 (rank : 226)
Query Neighborhood Hits	375	Target Neighborhood Hits	435	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.093986 (rank : 245)
Query Neighborhood Hits	375	Target Neighborhood Hits	440	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.097497 (rank : 220)
Query Neighborhood Hits	375	Target Neighborhood Hits	460	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.094174 (rank : 244)
Query Neighborhood Hits	375	Target Neighborhood Hits	413	Shared Neighborhood Hits	60
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.067290 (rank : 346)
Query Neighborhood Hits	375	Target Neighborhood Hits	292	Shared Neighborhood Hits	35
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.067375 (rank : 345)
Query Neighborhood Hits	375	Target Neighborhood Hits	317	Shared Neighborhood Hits	36
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.083695 (rank : 286)
Query Neighborhood Hits	375	Target Neighborhood Hits	325	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.072866 (rank : 321)
Query Neighborhood Hits	375	Target Neighborhood Hits	287	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.051494 (rank : 468)
Query Neighborhood Hits	375	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.060328 (rank : 378)
Query Neighborhood Hits	375	Target Neighborhood Hits	266	Shared Neighborhood Hits	30
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.083028 (rank : 288)
Query Neighborhood Hits	375	Target Neighborhood Hits	365	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.084868 (rank : 282)
Query Neighborhood Hits	375	Target Neighborhood Hits	379	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.094693 (rank : 243)
Query Neighborhood Hits	375	Target Neighborhood Hits	343	Shared Neighborhood Hits	44
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.092937 (rank : 250)
Query Neighborhood Hits	375	Target Neighborhood Hits	358	Shared Neighborhood Hits	44
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FAT2_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.070633 (rank : 328)
Query Neighborhood Hits	375	Target Neighborhood Hits	507	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FATH_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.085803 (rank : 278)
Query Neighborhood Hits	375	Target Neighborhood Hits	570	Shared Neighborhood Hits	50
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBLN1_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.101364 (rank : 198)
Query Neighborhood Hits	375	Target Neighborhood Hits	324	Shared Neighborhood Hits	43
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.099364 (rank : 206)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	43
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.092155 (rank : 253)
Query Neighborhood Hits	375	Target Neighborhood Hits	392	Shared Neighborhood Hits	48
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.096993 (rank : 229)
Query Neighborhood Hits	375	Target Neighborhood Hits	505	Shared Neighborhood Hits	71
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.101527 (rank : 197)
Query Neighborhood Hits	375	Target Neighborhood Hits	293	Shared Neighborhood Hits	40
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.098499 (rank : 210)
Query Neighborhood Hits	375	Target Neighborhood Hits	279	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.109478 (rank : 184)
Query Neighborhood Hits	375	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.110150 (rank : 182)
Query Neighborhood Hits	375	Target Neighborhood Hits	270	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.100051 (rank : 203)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.097071 (rank : 228)
Query Neighborhood Hits	375	Target Neighborhood Hits	317	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.102889 (rank : 192)
Query Neighborhood Hits	375	Target Neighborhood Hits	557	Shared Neighborhood Hits	69
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.099812 (rank : 204)
Query Neighborhood Hits	375	Target Neighborhood Hits	563	Shared Neighborhood Hits	72
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.097450 (rank : 222)
Query Neighborhood Hits	375	Target Neighborhood Hits	560	Shared Neighborhood Hits	70
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.097197 (rank : 227)
Query Neighborhood Hits	375	Target Neighborhood Hits	549	Shared Neighborhood Hits	70
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.097515 (rank : 219)
Query Neighborhood Hits	375	Target Neighborhood Hits	543	Shared Neighborhood Hits	57
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.088413 (rank : 273)
Query Neighborhood Hits	375	Target Neighborhood Hits	348	Shared Neighborhood Hits	40
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.088750 (rank : 271)
Query Neighborhood Hits	375	Target Neighborhood Hits	343	Shared Neighborhood Hits	40
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GP155_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.051948 (rank : 462)
Query Neighborhood Hits	375	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

ITB5_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.051415 (rank : 470)
Query Neighborhood Hits	375	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.051662 (rank : 467)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	40
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

JAG1_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.095338 (rank : 236)
Query Neighborhood Hits	375	Target Neighborhood Hits	514	Shared Neighborhood Hits	60
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.095118 (rank : 239)
Query Neighborhood Hits	375	Target Neighborhood Hits	518	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.092547 (rank : 252)
Query Neighborhood Hits	375	Target Neighborhood Hits	491	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.090404 (rank : 264)
Query Neighborhood Hits	375	Target Neighborhood Hits	504	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR101_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.073490 (rank : 319)
Query Neighborhood Hits	375	Target Neighborhood Hits	261	Shared Neighborhood Hits	45
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.067584 (rank : 343)
Query Neighborhood Hits	375	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.077524 (rank : 305)
Query Neighborhood Hits	375	Target Neighborhood Hits	313	Shared Neighborhood Hits	51
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.052585 (rank : 453)
Query Neighborhood Hits	375	Target Neighborhood Hits	271	Shared Neighborhood Hits	41
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.082082 (rank : 291)
Query Neighborhood Hits	375	Target Neighborhood Hits	347	Shared Neighborhood Hits	55
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.073870 (rank : 317)
Query Neighborhood Hits	375	Target Neighborhood Hits	330	Shared Neighborhood Hits	48
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.050042 (rank : 486)
Query Neighborhood Hits	375	Target Neighborhood Hits	226	Shared Neighborhood Hits	36
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.060718 (rank : 375)
Query Neighborhood Hits	375	Target Neighborhood Hits	226	Shared Neighborhood Hits	38
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KRA51_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.069807 (rank : 331)
Query Neighborhood Hits	375	Target Neighborhood Hits	288	Shared Neighborhood Hits	47
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.051350 (rank : 471)
Query Neighborhood Hits	375	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA58_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.053530 (rank : 438)
Query Neighborhood Hits	375	Target Neighborhood Hits	324	Shared Neighborhood Hits	38
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.052940 (rank : 447)
Query Neighborhood Hits	375	Target Neighborhood Hits	310	Shared Neighborhood Hits	41
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.054649 (rank : 428)
Query Neighborhood Hits	375	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA98_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.051756 (rank : 464)
Query Neighborhood Hits	375	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

LAMA1_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.051225 (rank : 474)
Query Neighborhood Hits	375	Target Neighborhood Hits	804	Shared Neighborhood Hits	50
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.052958 (rank : 446)
Query Neighborhood Hits	375	Target Neighborhood Hits	838	Shared Neighborhood Hits	48
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.051908 (rank : 463)
Query Neighborhood Hits	375	Target Neighborhood Hits	1092	Shared Neighborhood Hits	54
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.050843 (rank : 478)
Query Neighborhood Hits	375	Target Neighborhood Hits	1198	Shared Neighborhood Hits	53
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA5_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.061514 (rank : 367)
Query Neighborhood Hits	375	Target Neighborhood Hits	828	Shared Neighborhood Hits	62
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.060172 (rank : 380)
Query Neighborhood Hits	375	Target Neighborhood Hits	692	Shared Neighborhood Hits	44
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.052782 (rank : 448)
Query Neighborhood Hits	375	Target Neighborhood Hits	722	Shared Neighborhood Hits	44
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.051281 (rank : 473)
Query Neighborhood Hits	375	Target Neighborhood Hits	461	Shared Neighborhood Hits	33
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.052430 (rank : 456)
Query Neighborhood Hits	375	Target Neighborhood Hits	444	Shared Neighborhood Hits	40
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.051117 (rank : 476)
Query Neighborhood Hits	375	Target Neighborhood Hits	922	Shared Neighborhood Hits	52
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.053037 (rank : 445)
Query Neighborhood Hits	375	Target Neighborhood Hits	588	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.059561 (rank : 384)
Query Neighborhood Hits	375	Target Neighborhood Hits	624	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LDLR_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.065571 (rank : 351)
Query Neighborhood Hits	375	Target Neighborhood Hits	375	Shared Neighborhood Hits	51
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.060877 (rank : 373)
Query Neighborhood Hits	375	Target Neighborhood Hits	382	Shared Neighborhood Hits	50
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.076125 (rank : 311)
Query Neighborhood Hits	375	Target Neighborhood Hits	602	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.074257 (rank : 316)
Query Neighborhood Hits	375	Target Neighborhood Hits	606	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.078278 (rank : 303)
Query Neighborhood Hits	375	Target Neighborhood Hits	617	Shared Neighborhood Hits	71
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.076343 (rank : 310)
Query Neighborhood Hits	375	Target Neighborhood Hits	573	Shared Neighborhood Hits	64
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP4_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.058781 (rank : 394)
Query Neighborhood Hits	375	Target Neighborhood Hits	355	Shared Neighborhood Hits	45
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.058550 (rank : 395)
Query Neighborhood Hits	375	Target Neighborhood Hits	351	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.059454 (rank : 388)
Query Neighborhood Hits	375	Target Neighborhood Hits	346	Shared Neighborhood Hits	52
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.062158 (rank : 364)
Query Neighborhood Hits	375	Target Neighborhood Hits	385	Shared Neighborhood Hits	52
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.098377 (rank : 211)
Query Neighborhood Hits	375	Target Neighborhood Hits	553	Shared Neighborhood Hits	74
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.096191 (rank : 231)
Query Neighborhood Hits	375	Target Neighborhood Hits	514	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.096016 (rank : 232)
Query Neighborhood Hits	375	Target Neighborhood Hits	502	Shared Neighborhood Hits	57
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.094819 (rank : 241)
Query Neighborhood Hits	375	Target Neighborhood Hits	479	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.100192 (rank : 201)
Query Neighborhood Hits	375	Target Neighborhood Hits	552	Shared Neighborhood Hits	72
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.099766 (rank : 205)
Query Neighborhood Hits	375	Target Neighborhood Hits	617	Shared Neighborhood Hits	76
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.098189 (rank : 212)
Query Neighborhood Hits	375	Target Neighborhood Hits	502	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.095489 (rank : 233)
Query Neighborhood Hits	375	Target Neighborhood Hits	475	Shared Neighborhood Hits	62
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.110298 (rank : 181)
Query Neighborhood Hits	375	Target Neighborhood Hits	607	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYAM2_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.059542 (rank : 385)
Query Neighborhood Hits	375	Target Neighborhood Hits	394	Shared Neighborhood Hits	44
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.050786 (rank : 479)
Query Neighborhood Hits	375	Target Neighborhood Hits	420	Shared Neighborhood Hits	43
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MATN2_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.069321 (rank : 335)
Query Neighborhood Hits	375	Target Neighborhood Hits	365	Shared Neighborhood Hits	40
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.063849 (rank : 357)
Query Neighborhood Hits	375	Target Neighborhood Hits	356	Shared Neighborhood Hits	39
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.060785 (rank : 374)
Query Neighborhood Hits	375	Target Neighborhood Hits	268	Shared Neighborhood Hits	30
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.061405 (rank : 370)
Query Neighborhood Hits	375	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.065615 (rank : 350)
Query Neighborhood Hits	375	Target Neighborhood Hits	287	Shared Neighborhood Hits	37
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MEGF8_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.081247 (rank : 295)
Query Neighborhood Hits	375	Target Neighborhood Hits	528	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.078337 (rank : 302)
Query Neighborhood Hits	375	Target Neighborhood Hits	520	Shared Neighborhood Hits	51
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.076705 (rank : 308)
Query Neighborhood Hits	375	Target Neighborhood Hits	557	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MUC13_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.053229 (rank : 443)
Query Neighborhood Hits	375	Target Neighborhood Hits	447	Shared Neighborhood Hits	60
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC2_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.082732 (rank : 289)
Query Neighborhood Hits	375	Target Neighborhood Hits	906	Shared Neighborhood Hits	125
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.081480 (rank : 292)
Query Neighborhood Hits	375	Target Neighborhood Hits	1020	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUC7_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.055177 (rank : 413)
Query Neighborhood Hits	375	Target Neighborhood Hits	538	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUCDL_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.075632 (rank : 313)
Query Neighborhood Hits	375	Target Neighborhood Hits	777	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUCDL_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.059342 (rank : 389)
Query Neighborhood Hits	375	Target Neighborhood Hits	461	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYOC_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.053577 (rank : 437)
Query Neighborhood Hits	375	Target Neighborhood Hits	489	Shared Neighborhood Hits	5
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

MYOC_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.063359 (rank : 359)
Query Neighborhood Hits	375	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

NELL1_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.133227 (rank : 161)
Query Neighborhood Hits	375	Target Neighborhood Hits	451	Shared Neighborhood Hits	58
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.126001 (rank : 166)
Query Neighborhood Hits	375	Target Neighborhood Hits	449	Shared Neighborhood Hits	48
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.129919 (rank : 164)
Query Neighborhood Hits	375	Target Neighborhood Hits	436	Shared Neighborhood Hits	48
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NID1_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.097915 (rank : 217)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.095024 (rank : 240)
Query Neighborhood Hits	375	Target Neighborhood Hits	335	Shared Neighborhood Hits	37
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.096223 (rank : 230)
Query Neighborhood Hits	375	Target Neighborhood Hits	456	Shared Neighborhood Hits	51
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.095423 (rank : 234)
Query Neighborhood Hits	375	Target Neighborhood Hits	338	Shared Neighborhood Hits	41
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOE1_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.055186 (rank : 412)
Query Neighborhood Hits	375	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

NOE1_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.055757 (rank : 408)
Query Neighborhood Hits	375	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

NOE2_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.059527 (rank : 386)
Query Neighborhood Hits	375	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O95897, Q6IMJ3, Q96FC2	Gene names	OLFM2, NOE2
Domain Architecture
Description	Noelin-2 precursor (Olfactomedin-2).

NOE2_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.059494 (rank : 387)
Query Neighborhood Hits	375	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM13	Gene names	Olfm2
Domain Architecture	No domain graphic available
Description	Noelin-2 precursor (Olfactomedin-2).

NOE3_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.057723 (rank : 399)
Query Neighborhood Hits	375	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PB7, Q8TBG1, Q96PB2, Q96PB3, Q96PB4, Q96PB5, Q96PB6	Gene names	OLFM3, NOE3
Domain Architecture
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

NOE3_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.057731 (rank : 398)
Query Neighborhood Hits	375	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	P63056, Q8BKV2, Q8BLL6, Q8QZW0, Q8R4K3, Q8R4K4	Gene names	Olfm3, Noe3
Domain Architecture	No domain graphic available
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

NOTC1_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.091362 (rank : 259)
Query Neighborhood Hits	375	Target Neighborhood Hits	906	Shared Neighborhood Hits	84
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.091682 (rank : 256)
Query Neighborhood Hits	375	Target Neighborhood Hits	916	Shared Neighborhood Hits	79
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.091148 (rank : 261)
Query Neighborhood Hits	375	Target Neighborhood Hits	1069	Shared Neighborhood Hits	97
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.091933 (rank : 254)
Query Neighborhood Hits	375	Target Neighborhood Hits	905	Shared Neighborhood Hits	81
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.090844 (rank : 262)
Query Neighborhood Hits	375	Target Neighborhood Hits	872	Shared Neighborhood Hits	71
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NRX1A_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.067376 (rank : 344)
Query Neighborhood Hits	375	Target Neighborhood Hits	170	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.067690 (rank : 342)
Query Neighborhood Hits	375	Target Neighborhood Hits	164	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.068847 (rank : 339)
Query Neighborhood Hits	375	Target Neighborhood Hits	164	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

OLFL1_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.062223 (rank : 363)
Query Neighborhood Hits	375	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWY5	Gene names	OLFML1
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 1 precursor.

OLFL3_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.058956 (rank : 393)
Query Neighborhood Hits	375	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRN5, Q53FR1, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2	Gene names	OLFML3
Domain Architecture
Description	Olfactomedin-like protein 3 precursor (HNOEL-iso) (hOLF44).

OLFL3_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.058974 (rank : 392)
Query Neighborhood Hits	375	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BK62, Q3V2F2, Q8C1T0, Q99K37	Gene names	Olfml3
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 3 precursor.

PC11X_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.054807 (rank : 422)
Query Neighborhood Hits	375	Target Neighborhood Hits	199	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

PC11Y_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.055152 (rank : 415)
Query Neighborhood Hits	375	Target Neighborhood Hits	205	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

PCD15_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.070580 (rank : 329)
Query Neighborhood Hits	375	Target Neighborhood Hits	289	Shared Neighborhood Hits	57
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.069577 (rank : 332)
Query Neighborhood Hits	375	Target Neighborhood Hits	262	Shared Neighborhood Hits	51
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD16_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.064497 (rank : 354)
Query Neighborhood Hits	375	Target Neighborhood Hits	245	Shared Neighborhood Hits	21
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCD20_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.054841 (rank : 419)
Query Neighborhood Hits	375	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N6Y1, Q8NDN4, Q9NRT9	Gene names	PCDH20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor (Protocadherin-13).

PCD20_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.054818 (rank : 421)
Query Neighborhood Hits	375	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BIZ0, Q8BIV2	Gene names	Pcdh20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor.

PCDH1_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.056841 (rank : 403)
Query Neighborhood Hits	375	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

PCDH7_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.055826 (rank : 407)
Query Neighborhood Hits	375	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PCDH9_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.055170 (rank : 414)
Query Neighborhood Hits	375	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

PCDLK_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.063824 (rank : 358)
Query Neighborhood Hits	375	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

PCSK5_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.064172 (rank : 356)
Query Neighborhood Hits	375	Target Neighborhood Hits	613	Shared Neighborhood Hits	69
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PGBM_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.072840 (rank : 322)
Query Neighborhood Hits	375	Target Neighborhood Hits	1113	Shared Neighborhood Hits	80
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.071972 (rank : 325)
Query Neighborhood Hits	375	Target Neighborhood Hits	1073	Shared Neighborhood Hits	71
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PRB4S_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.052174 (rank : 459)
Query Neighborhood Hits	375	Target Neighborhood Hits	330	Shared Neighborhood Hits	84
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PROS_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.095127 (rank : 238)
Query Neighborhood Hits	375	Target Neighborhood Hits	340	Shared Neighborhood Hits	38
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.094795 (rank : 242)
Query Neighborhood Hits	375	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.054673 (rank : 425)
Query Neighborhood Hits	375	Target Neighborhood Hits	422	Shared Neighborhood Hits	34
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.053283 (rank : 441)
Query Neighborhood Hits	375	Target Neighborhood Hits	410	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRP1_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.061484 (rank : 368)
Query Neighborhood Hits	375	Target Neighborhood Hits	385	Shared Neighborhood Hits	99
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.064326 (rank : 355)
Query Neighborhood Hits	375	Target Neighborhood Hits	347	Shared Neighborhood Hits	102
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.054910 (rank : 418)
Query Neighborhood Hits	375	Target Neighborhood Hits	460	Shared Neighborhood Hits	108
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.050276 (rank : 482)
Query Neighborhood Hits	375	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

ROBO4_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.053042 (rank : 444)
Query Neighborhood Hits	375	Target Neighborhood Hits	364	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

ROBO4_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.053691 (rank : 436)
Query Neighborhood Hits	375	Target Neighborhood Hits	358	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

RSPO4_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.097920 (rank : 216)
Query Neighborhood Hits	375	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SCUB3_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.091307 (rank : 260)
Query Neighborhood Hits	375	Target Neighborhood Hits	428	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.091508 (rank : 258)
Query Neighborhood Hits	375	Target Neighborhood Hits	442	Shared Neighborhood Hits	47
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEM3A_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.051683 (rank : 465)
Query Neighborhood Hits	375	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

SEM3A_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.050994 (rank : 477)
Query Neighborhood Hits	375	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

SEM3B_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.051671 (rank : 466)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

SEM3B_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.050290 (rank : 481)
Query Neighborhood Hits	375	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

SEM3C_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.055711 (rank : 410)
Query Neighborhood Hits	375	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3C_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.055718 (rank : 409)
Query Neighborhood Hits	375	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3D_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.050107 (rank : 483)
Query Neighborhood Hits	375	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SEM3E_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.051166 (rank : 475)
Query Neighborhood Hits	375	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM3E_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.051439 (rank : 469)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM3F_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.055038 (rank : 417)
Query Neighborhood Hits	375	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEM3F_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.052637 (rank : 451)
Query Neighborhood Hits	375	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM4A_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.055393 (rank : 411)
Query Neighborhood Hits	375	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4A_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.054775 (rank : 423)
Query Neighborhood Hits	375	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4B_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.053901 (rank : 433)
Query Neighborhood Hits	375	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

SEM4B_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.053768 (rank : 435)
Query Neighborhood Hits	375	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

SEM4C_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.057045 (rank : 402)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM4C_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.055140 (rank : 416)
Query Neighborhood Hits	375	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM4D_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.054207 (rank : 432)
Query Neighborhood Hits	375	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM4D_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.052705 (rank : 450)
Query Neighborhood Hits	375	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SEM4F_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.051975 (rank : 461)
Query Neighborhood Hits	375	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

SEM4F_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.052613 (rank : 452)
Query Neighborhood Hits	375	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SEM4G_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.050323 (rank : 480)
Query Neighborhood Hits	375	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SEM6A_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.056840 (rank : 404)
Query Neighborhood Hits	375	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM6A_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.057365 (rank : 401)
Query Neighborhood Hits	375	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM6B_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.060879 (rank : 372)
Query Neighborhood Hits	375	Target Neighborhood Hits	187	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM6B_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.059135 (rank : 391)
Query Neighborhood Hits	375	Target Neighborhood Hits	200	Shared Neighborhood Hits	15
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM6C_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.060931 (rank : 371)
Query Neighborhood Hits	375	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6C_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.061896 (rank : 365)
Query Neighborhood Hits	375	Target Neighborhood Hits	352	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6D_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.057380 (rank : 400)
Query Neighborhood Hits	375	Target Neighborhood Hits	169	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6D_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.057976 (rank : 397)
Query Neighborhood Hits	375	Target Neighborhood Hits	161	Shared Neighborhood Hits	17
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SLIT1_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.080011 (rank : 299)
Query Neighborhood Hits	375	Target Neighborhood Hits	700	Shared Neighborhood Hits	55
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.082087 (rank : 290)
Query Neighborhood Hits	375	Target Neighborhood Hits	715	Shared Neighborhood Hits	59
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.085612 (rank : 280)
Query Neighborhood Hits	375	Target Neighborhood Hits	708	Shared Neighborhood Hits	58
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.081374 (rank : 293)
Query Neighborhood Hits	375	Target Neighborhood Hits	684	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.079989 (rank : 300)
Query Neighborhood Hits	375	Target Neighborhood Hits	682	Shared Neighborhood Hits	53
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.081348 (rank : 294)
Query Neighborhood Hits	375	Target Neighborhood Hits	700	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SREC2_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.085357 (rank : 281)
Query Neighborhood Hits	375	Target Neighborhood Hits	645	Shared Neighborhood Hits	102
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.081226 (rank : 296)
Query Neighborhood Hits	375	Target Neighborhood Hits	605	Shared Neighborhood Hits	93
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.086908 (rank : 276)
Query Neighborhood Hits	375	Target Neighborhood Hits	645	Shared Neighborhood Hits	78
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.089984 (rank : 268)
Query Neighborhood Hits	375	Target Neighborhood Hits	566	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.090248 (rank : 266)
Query Neighborhood Hits	375	Target Neighborhood Hits	534	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.097267 (rank : 225)
Query Neighborhood Hits	375	Target Neighborhood Hits	528	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUSD1_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.117018 (rank : 172)
Query Neighborhood Hits	375	Target Neighborhood Hits	285	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TRBM_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.102375 (rank : 194)
Query Neighborhood Hits	375	Target Neighborhood Hits	339	Shared Neighborhood Hits	45
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.102762 (rank : 193)
Query Neighborhood Hits	375	Target Neighborhood Hits	361	Shared Neighborhood Hits	47
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP3_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.156499 (rank : 154)
Query Neighborhood Hits	375	Target Neighborhood Hits	250	Shared Neighborhood Hits	31
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.152926 (rank : 156)
Query Neighborhood Hits	375	Target Neighborhood Hits	247	Shared Neighborhood Hits	31
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.148400 (rank : 158)
Query Neighborhood Hits	375	Target Neighborhood Hits	277	Shared Neighborhood Hits	37
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 654)	NC score	0.147728 (rank : 159)
Query Neighborhood Hits	375	Target Neighborhood Hits	276	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.116239 (rank : 173)
Query Neighborhood Hits	375	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.107438 (rank : 187)
Query Neighborhood Hits	375	Target Neighborhood Hits	276	Shared Neighborhood Hits	40
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.052272 (rank : 457)
Query Neighborhood Hits	375	Target Neighborhood Hits	626	Shared Neighborhood Hits	50
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VLDLR_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.055997 (rank : 406)
Query Neighborhood Hits	375	Target Neighborhood Hits	383	Shared Neighborhood Hits	43
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.054656 (rank : 426)
Query Neighborhood Hits	375	Target Neighborhood Hits	360	Shared Neighborhood Hits	42
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.050075 (rank : 485)
Query Neighborhood Hits	375	Target Neighborhood Hits	381	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WASIP_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.053390 (rank : 440)
Query Neighborhood Hits	375	Target Neighborhood Hits	458	Shared Neighborhood Hits	106
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.059664 (rank : 382)
Query Neighborhood Hits	375	Target Neighborhood Hits	392	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WIF1_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.062984 (rank : 361)
Query Neighborhood Hits	375	Target Neighborhood Hits	392	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.063086 (rank : 360)
Query Neighborhood Hits	375	Target Neighborhood Hits	393	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WISP3_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.072139 (rank : 324)
Query Neighborhood Hits	375	Target Neighborhood Hits	87	Shared Neighborhood Hits	42
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ZAN_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.084395 (rank : 284)
Query Neighborhood Hits	375	Target Neighborhood Hits	679	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 667)	NC score	0.102299 (rank : 195)
Query Neighborhood Hits	375	Target Neighborhood Hits	808	Shared Neighborhood Hits	102
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

BAI1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	375	Target Neighborhood Hits	375	Shared Neighborhood Hits	375
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
NC score	0.995357 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	375	Target Neighborhood Hits	340	Shared Neighborhood Hits	286
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_MOUSE
NC score	0.981146 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	375	Target Neighborhood Hits	250	Shared Neighborhood Hits	186
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_HUMAN
NC score	0.980568 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	375	Target Neighborhood Hits	246	Shared Neighborhood Hits	182
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI2_MOUSE
NC score	0.976707 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	375	Target Neighborhood Hits	323	Shared Neighborhood Hits	196
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
NC score	0.976087 (rank : 6)	θ value	0 (rank : 3)
Query Neighborhood Hits	375	Target Neighborhood Hits	332	Shared Neighborhood Hits	198
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

PROP_MOUSE
NC score	0.716772 (rank : 7)	θ value	7.03111e-45 (rank : 10)
Query Neighborhood Hits	375	Target Neighborhood Hits	165	Shared Neighborhood Hits	93
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROP_HUMAN
NC score	0.707188 (rank : 8)	θ value	1.20211e-36 (rank : 26)
Query Neighborhood Hits	375	Target Neighborhood Hits	126	Shared Neighborhood Hits	92
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

GP133_HUMAN
NC score	0.706017 (rank : 9)	θ value	4.568e-36 (rank : 27)
Query Neighborhood Hits	375	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

EMR4_MOUSE
NC score	0.691238 (rank : 10)	θ value	1.20211e-36 (rank : 25)
Query Neighborhood Hits	375	Target Neighborhood Hits	191	Shared Neighborhood Hits	87
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

GP113_HUMAN
NC score	0.688484 (rank : 11)	θ value	1.08979e-29 (rank : 32)
Query Neighborhood Hits	375	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP128_HUMAN
NC score	0.665736 (rank : 12)	θ value	4.9032e-22 (rank : 49)
Query Neighborhood Hits	375	Target Neighborhood Hits	135	Shared Neighborhood Hits	84
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GPR64_MOUSE
NC score	0.664686 (rank : 13)	θ value	2.59989e-23 (rank : 43)
Query Neighborhood Hits	375	Target Neighborhood Hits	156	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR64_HUMAN
NC score	0.662564 (rank : 14)	θ value	1.99067e-23 (rank : 42)
Query Neighborhood Hits	375	Target Neighborhood Hits	207	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

ELTD1_HUMAN
NC score	0.653374 (rank : 15)	θ value	1.85889e-29 (rank : 35)
Query Neighborhood Hits	375	Target Neighborhood Hits	269	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

EMR3_HUMAN
NC score	0.652461 (rank : 16)	θ value	1.4233e-29 (rank : 34)
Query Neighborhood Hits	375	Target Neighborhood Hits	245	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

GPR97_MOUSE
NC score	0.644057 (rank : 17)	θ value	1.42661e-21 (rank : 50)
Query Neighborhood Hits	375	Target Neighborhood Hits	89	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

LPHN1_HUMAN
NC score	0.636572 (rank : 18)	θ value	1.6774e-38 (rank : 18)
Query Neighborhood Hits	375	Target Neighborhood Hits	155	Shared Neighborhood Hits	91
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

SPON1_MOUSE
NC score	0.636357 (rank : 19)	θ value	2.96777e-27 (rank : 37)
Query Neighborhood Hits	375	Target Neighborhood Hits	123	Shared Neighborhood Hits	98
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
NC score	0.635530 (rank : 20)	θ value	2.96777e-27 (rank : 36)
Query Neighborhood Hits	375	Target Neighborhood Hits	117	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

LPHN3_HUMAN
NC score	0.634118 (rank : 21)	θ value	1.42001e-37 (rank : 23)
Query Neighborhood Hits	375	Target Neighborhood Hits	139	Shared Neighborhood Hits	91
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

GP144_HUMAN
NC score	0.633205 (rank : 22)	θ value	5.42112e-21 (rank : 54)
Query Neighborhood Hits	375	Target Neighborhood Hits	108	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GP110_HUMAN
NC score	0.630585 (rank : 23)	θ value	1.5242e-23 (rank : 41)
Query Neighborhood Hits	375	Target Neighborhood Hits	87	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP128_MOUSE
NC score	0.628042 (rank : 24)	θ value	1.58096e-12 (rank : 80)
Query Neighborhood Hits	375	Target Neighborhood Hits	141	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

LPHN2_HUMAN
NC score	0.627555 (rank : 25)	θ value	4.88048e-38 (rank : 21)
Query Neighborhood Hits	375	Target Neighborhood Hits	136	Shared Neighborhood Hits	84
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

GP116_HUMAN
NC score	0.626919 (rank : 26)	θ value	1.86321e-21 (rank : 52)
Query Neighborhood Hits	375	Target Neighborhood Hits	167	Shared Neighborhood Hits	70
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP110_MOUSE
NC score	0.621490 (rank : 27)	θ value	3.28887e-18 (rank : 59)
Query Neighborhood Hits	375	Target Neighborhood Hits	92	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GPR97_HUMAN
NC score	0.614626 (rank : 28)	θ value	8.10077e-17 (rank : 62)
Query Neighborhood Hits	375	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GPR56_HUMAN
NC score	0.614448 (rank : 29)	θ value	1.42992e-13 (rank : 75)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GP114_HUMAN
NC score	0.612376 (rank : 30)	θ value	3.18553e-13 (rank : 77)
Query Neighborhood Hits	375	Target Neighborhood Hits	75	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP112_HUMAN
NC score	0.609566 (rank : 31)	θ value	1.05554e-24 (rank : 39)
Query Neighborhood Hits	375	Target Neighborhood Hits	441	Shared Neighborhood Hits	111
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP115_MOUSE
NC score	0.609320 (rank : 32)	θ value	4.29542e-18 (rank : 60)
Query Neighborhood Hits	375	Target Neighborhood Hits	69	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP115_HUMAN
NC score	0.607919 (rank : 33)	θ value	5.60996e-18 (rank : 61)
Query Neighborhood Hits	375	Target Neighborhood Hits	87	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GPR56_MOUSE
NC score	0.593526 (rank : 34)	θ value	7.34386e-10 (rank : 95)
Query Neighborhood Hits	375	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

ELTD1_MOUSE
NC score	0.582142 (rank : 35)	θ value	1.4233e-29 (rank : 33)
Query Neighborhood Hits	375	Target Neighborhood Hits	288	Shared Neighborhood Hits	99
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

GP126_HUMAN
NC score	0.565571 (rank : 36)	θ value	3.51386e-20 (rank : 55)
Query Neighborhood Hits	375	Target Neighborhood Hits	187	Shared Neighborhood Hits	89
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP111_HUMAN
NC score	0.561220 (rank : 37)	θ value	7.58209e-15 (rank : 72)
Query Neighborhood Hits	375	Target Neighborhood Hits	77	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

CD97_MOUSE
NC score	0.554007 (rank : 38)	θ value	9.87957e-23 (rank : 45)
Query Neighborhood Hits	375	Target Neighborhood Hits	295	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

TSP2_MOUSE
NC score	0.537064 (rank : 39)	θ value	1.08726e-37 (rank : 22)
Query Neighborhood Hits	375	Target Neighborhood Hits	352	Shared Neighborhood Hits	119
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_HUMAN
NC score	0.537049 (rank : 40)	θ value	4.41421e-39 (rank : 16)
Query Neighborhood Hits	375	Target Neighborhood Hits	359	Shared Neighborhood Hits	118
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

UNC5A_MOUSE
NC score	0.534337 (rank : 41)	θ value	3.75424e-22 (rank : 47)
Query Neighborhood Hits	375	Target Neighborhood Hits	203	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

TSP1_MOUSE
NC score	0.530369 (rank : 42)	θ value	7.52953e-39 (rank : 17)
Query Neighborhood Hits	375	Target Neighborhood Hits	396	Shared Neighborhood Hits	117
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

UNC5B_MOUSE
NC score	0.529054 (rank : 43)	θ value	3.75424e-22 (rank : 48)
Query Neighborhood Hits	375	Target Neighborhood Hits	226	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

ATL2_MOUSE
NC score	0.528141 (rank : 44)	θ value	8.95645e-16 (rank : 69)
Query Neighborhood Hits	375	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

UNC5B_HUMAN
NC score	0.527283 (rank : 45)	θ value	1.6852e-22 (rank : 46)
Query Neighborhood Hits	375	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

TSP1_HUMAN
NC score	0.527141 (rank : 46)	θ value	1.6774e-38 (rank : 19)
Query Neighborhood Hits	375	Target Neighborhood Hits	389	Shared Neighborhood Hits	118
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ATL2_HUMAN
NC score	0.526627 (rank : 47)	θ value	6.85773e-16 (rank : 67)
Query Neighborhood Hits	375	Target Neighborhood Hits	125	Shared Neighborhood Hits	85
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

CD97_HUMAN
NC score	0.518788 (rank : 48)	θ value	1.37539e-32 (rank : 31)
Query Neighborhood Hits	375	Target Neighborhood Hits	353	Shared Neighborhood Hits	101
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

UNC5C_HUMAN
NC score	0.516121 (rank : 49)	θ value	1.86321e-21 (rank : 53)
Query Neighborhood Hits	375	Target Neighborhood Hits	226	Shared Neighborhood Hits	82
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
NC score	0.516096 (rank : 50)	θ value	1.42661e-21 (rank : 51)
Query Neighborhood Hits	375	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

EMR1_MOUSE
NC score	0.515006 (rank : 51)	θ value	7.29293e-34 (rank : 29)
Query Neighborhood Hits	375	Target Neighborhood Hits	349	Shared Neighborhood Hits	99
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
NC score	0.499401 (rank : 52)	θ value	1.37858e-24 (rank : 40)
Query Neighborhood Hits	375	Target Neighborhood Hits	345	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

UNC5D_HUMAN
NC score	0.493514 (rank : 53)	θ value	5.25075e-16 (rank : 66)
Query Neighborhood Hits	375	Target Neighborhood Hits	267	Shared Neighborhood Hits	81
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.491831 (rank : 54)	θ value	2.35696e-16 (rank : 64)
Query Neighborhood Hits	375	Target Neighborhood Hits	268	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

EMR1_HUMAN
NC score	0.489217 (rank : 55)	θ value	9.54697e-26 (rank : 38)
Query Neighborhood Hits	375	Target Neighborhood Hits	382	Shared Neighborhood Hits	103
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

ATS9_HUMAN
NC score	0.487296 (rank : 56)	θ value	3.39556e-23 (rank : 44)
Query Neighborhood Hits	375	Target Neighborhood Hits	219	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS18_MOUSE
NC score	0.484623 (rank : 57)	θ value	1.74391e-19 (rank : 56)
Query Neighborhood Hits	375	Target Neighborhood Hits	163	Shared Neighborhood Hits	87
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS13_HUMAN
NC score	0.483493 (rank : 58)	θ value	2.69671e-12 (rank : 81)
Query Neighborhood Hits	375	Target Neighborhood Hits	238	Shared Neighborhood Hits	89
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

CRFR1_MOUSE
NC score	0.481194 (rank : 59)	θ value	2.69671e-12 (rank : 82)
Query Neighborhood Hits	375	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

ATS16_MOUSE
NC score	0.480727 (rank : 60)	θ value	6.85773e-16 (rank : 68)
Query Neighborhood Hits	375	Target Neighborhood Hits	179	Shared Neighborhood Hits	92
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS18_HUMAN
NC score	0.479454 (rank : 61)	θ value	1.13037e-18 (rank : 58)
Query Neighborhood Hits	375	Target Neighborhood Hits	169	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_HUMAN
NC score	0.478978 (rank : 62)	θ value	9.90251e-15 (rank : 73)
Query Neighborhood Hits	375	Target Neighborhood Hits	208	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS13_MOUSE
NC score	0.478930 (rank : 63)	θ value	4.76016e-09 (rank : 103)
Query Neighborhood Hits	375	Target Neighborhood Hits	227	Shared Neighborhood Hits	94
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS20_MOUSE
NC score	0.478469 (rank : 64)	θ value	3.88503e-19 (rank : 57)
Query Neighborhood Hits	375	Target Neighborhood Hits	225	Shared Neighborhood Hits	97
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CRFR2_MOUSE
NC score	0.477639 (rank : 65)	θ value	1.02475e-11 (rank : 86)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	75
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

ATS17_HUMAN
NC score	0.477542 (rank : 66)	θ value	4.02038e-16 (rank : 65)
Query Neighborhood Hits	375	Target Neighborhood Hits	194	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

CRFR1_HUMAN
NC score	0.476604 (rank : 67)	θ value	1.2105e-12 (rank : 79)
Query Neighborhood Hits	375	Target Neighborhood Hits	82	Shared Neighborhood Hits	74
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

CRFR2_HUMAN
NC score	0.473292 (rank : 68)	θ value	2.69671e-12 (rank : 83)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	75
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

ATS20_HUMAN
NC score	0.468915 (rank : 69)	θ value	1.38178e-16 (rank : 63)
Query Neighborhood Hits	375	Target Neighborhood Hits	192	Shared Neighborhood Hits	99
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATL5_HUMAN
NC score	0.466211 (rank : 70)	θ value	1.69304e-06 (rank : 121)
Query Neighborhood Hits	375	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATS2_HUMAN
NC score	0.466139 (rank : 71)	θ value	1.133e-10 (rank : 90)
Query Neighborhood Hits	375	Target Neighborhood Hits	179	Shared Neighborhood Hits	86
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
NC score	0.463222 (rank : 72)	θ value	9.59137e-10 (rank : 97)
Query Neighborhood Hits	375	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS14_HUMAN
NC score	0.462839 (rank : 73)	θ value	3.52202e-12 (rank : 84)
Query Neighborhood Hits	375	Target Neighborhood Hits	382	Shared Neighborhood Hits	112
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

SEM5B_MOUSE
NC score	0.462638 (rank : 74)	θ value	8.04462e-41 (rank : 13)
Query Neighborhood Hits	375	Target Neighborhood Hits	190	Shared Neighborhood Hits	96
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

ATL1_HUMAN
NC score	0.462257 (rank : 75)	θ value	2.21117e-06 (rank : 122)
Query Neighborhood Hits	375	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

SEM5A_HUMAN
NC score	0.460943 (rank : 76)	θ value	8.61488e-35 (rank : 28)
Query Neighborhood Hits	375	Target Neighborhood Hits	177	Shared Neighborhood Hits	92
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_HUMAN
NC score	0.460175 (rank : 77)	θ value	1.05066e-40 (rank : 14)
Query Neighborhood Hits	375	Target Neighborhood Hits	178	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ATL1_MOUSE
NC score	0.458695 (rank : 78)	θ value	1.87187e-05 (rank : 129)
Query Neighborhood Hits	375	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATS19_MOUSE
NC score	0.457752 (rank : 79)	θ value	1.99529e-15 (rank : 70)
Query Neighborhood Hits	375	Target Neighborhood Hits	188	Shared Neighborhood Hits	84
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS12_MOUSE
NC score	0.456244 (rank : 80)	θ value	4.30538e-10 (rank : 93)
Query Neighborhood Hits	375	Target Neighborhood Hits	220	Shared Neighborhood Hits	93
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS8_MOUSE
NC score	0.456224 (rank : 81)	θ value	1.63604e-09 (rank : 100)
Query Neighborhood Hits	375	Target Neighborhood Hits	139	Shared Neighborhood Hits	84
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS12_HUMAN
NC score	0.455661 (rank : 82)	θ value	9.59137e-10 (rank : 96)
Query Neighborhood Hits	375	Target Neighborhood Hits	251	Shared Neighborhood Hits	96
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

SEM5A_MOUSE
NC score	0.455401 (rank : 83)	θ value	1.24399e-33 (rank : 30)
Query Neighborhood Hits	375	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATS4_HUMAN
NC score	0.453955 (rank : 84)	θ value	1.38499e-08 (rank : 109)
Query Neighborhood Hits	375	Target Neighborhood Hits	138	Shared Neighborhood Hits	78
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
NC score	0.453734 (rank : 85)	θ value	4.76016e-09 (rank : 104)
Query Neighborhood Hits	375	Target Neighborhood Hits	145	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS1_MOUSE
NC score	0.452723 (rank : 86)	θ value	7.84624e-12 (rank : 85)
Query Neighborhood Hits	375	Target Neighborhood Hits	158	Shared Neighborhood Hits	87
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS19_HUMAN
NC score	0.452061 (rank : 87)	θ value	5.8054e-15 (rank : 71)
Query Neighborhood Hits	375	Target Neighborhood Hits	203	Shared Neighborhood Hits	99
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS8_HUMAN
NC score	0.451981 (rank : 88)	θ value	8.11959e-09 (rank : 105)
Query Neighborhood Hits	375	Target Neighborhood Hits	145	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS1_HUMAN
NC score	0.450429 (rank : 89)	θ value	1.74796e-11 (rank : 89)
Query Neighborhood Hits	375	Target Neighborhood Hits	159	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS6_HUMAN
NC score	0.447101 (rank : 90)	θ value	9.59137e-10 (rank : 98)
Query Neighborhood Hits	375	Target Neighborhood Hits	141	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

GPR98_HUMAN
NC score	0.446992 (rank : 91)	θ value	1.02475e-11 (rank : 87)
Query Neighborhood Hits	375	Target Neighborhood Hits	202	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

ATS3_HUMAN
NC score	0.446958 (rank : 92)	θ value	1.133e-10 (rank : 91)
Query Neighborhood Hits	375	Target Neighborhood Hits	179	Shared Neighborhood Hits	89
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS7_HUMAN
NC score	0.445427 (rank : 93)	θ value	2.13673e-09 (rank : 101)
Query Neighborhood Hits	375	Target Neighborhood Hits	169	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS15_HUMAN
NC score	0.443777 (rank : 94)	θ value	3.64472e-09 (rank : 102)
Query Neighborhood Hits	375	Target Neighborhood Hits	151	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

CALCR_HUMAN
NC score	0.443221 (rank : 95)	θ value	5.43371e-13 (rank : 78)
Query Neighborhood Hits	375	Target Neighborhood Hits	67	Shared Neighborhood Hits	66
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

THSD1_HUMAN
NC score	0.437579 (rank : 96)	θ value	2.88788e-06 (rank : 124)
Query Neighborhood Hits	375	Target Neighborhood Hits	136	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ATL3_HUMAN
NC score	0.436877 (rank : 97)	θ value	2.88119e-14 (rank : 74)
Query Neighborhood Hits	375	Target Neighborhood Hits	414	Shared Neighborhood Hits	94
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

GP123_HUMAN
NC score	0.435826 (rank : 98)	θ value	2.61198e-07 (rank : 119)
Query Neighborhood Hits	375	Target Neighborhood Hits	120	Shared Neighborhood Hits	48
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

GPR98_MOUSE
NC score	0.434594 (rank : 99)	θ value	4.30538e-10 (rank : 94)
Query Neighborhood Hits	375	Target Neighborhood Hits	206	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

SSPO_MOUSE
NC score	0.433688 (rank : 100)	θ value	3.16345e-37 (rank : 24)
Query Neighborhood Hits	375	Target Neighborhood Hits	800	Shared Neighborhood Hits	151
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ATS5_MOUSE
NC score	0.432346 (rank : 101)	θ value	6.87365e-08 (rank : 116)
Query Neighborhood Hits	375	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

THSD1_MOUSE
NC score	0.427953 (rank : 102)	θ value	6.43352e-06 (rank : 128)
Query Neighborhood Hits	375	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ATS5_HUMAN
NC score	0.424460 (rank : 103)	θ value	1.53129e-07 (rank : 118)
Query Neighborhood Hits	375	Target Neighborhood Hits	141	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

CALCR_MOUSE
NC score	0.422833 (rank : 104)	θ value	8.11959e-09 (rank : 106)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	70
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

VIPR1_MOUSE
NC score	0.419031 (rank : 105)	θ value	3.08544e-08 (rank : 114)
Query Neighborhood Hits	375	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	P97751, Q9JI40, Q9R1T8	Gene names	Vipr1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (VPAC1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

VIPR2_MOUSE
NC score	0.418623 (rank : 106)	θ value	8.11959e-09 (rank : 107)
Query Neighborhood Hits	375	Target Neighborhood Hits	98	Shared Neighborhood Hits	75
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

VIPR2_HUMAN
NC score	0.414399 (rank : 107)	θ value	3.29651e-10 (rank : 92)
Query Neighborhood Hits	375	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

PACR_MOUSE
NC score	0.411280 (rank : 108)	θ value	1.87187e-05 (rank : 131)
Query Neighborhood Hits	375	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	P70205	Gene names	Adcyap1r1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

PTHR1_HUMAN
NC score	0.406303 (rank : 109)	θ value	2.36244e-08 (rank : 112)
Query Neighborhood Hits	375	Target Neighborhood Hits	85	Shared Neighborhood Hits	77
SwissProt Accessions	Q03431	Gene names	PTHR1, PTHR
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

UNC5A_HUMAN
NC score	0.406135 (rank : 110)	θ value	3.08544e-08 (rank : 113)
Query Neighborhood Hits	375	Target Neighborhood Hits	198	Shared Neighborhood Hits	76
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

VIPR1_HUMAN
NC score	0.397040 (rank : 111)	θ value	2.61198e-07 (rank : 120)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	72
SwissProt Accessions	P32241, Q15871	Gene names	VIPR1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

PACR_HUMAN
NC score	0.396750 (rank : 112)	θ value	0.000121331 (rank : 138)
Query Neighborhood Hits	375	Target Neighborhood Hits	86	Shared Neighborhood Hits	78
SwissProt Accessions	P41586	Gene names	ADCYAP1R1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

CALRL_HUMAN
NC score	0.394069 (rank : 113)	θ value	2.44474e-05 (rank : 132)
Query Neighborhood Hits	375	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q16602	Gene names	CALCRL, CGRPR
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

CO6_HUMAN
NC score	0.393192 (rank : 114)	θ value	1.38499e-08 (rank : 110)
Query Neighborhood Hits	375	Target Neighborhood Hits	331	Shared Neighborhood Hits	101
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

PTHR1_MOUSE
NC score	0.391061 (rank : 115)	θ value	4.0297e-08 (rank : 115)
Query Neighborhood Hits	375	Target Neighborhood Hits	90	Shared Neighborhood Hits	75
SwissProt Accessions	P41593, Q62119	Gene names	Pthr1, Pthr
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

CALRL_MOUSE
NC score	0.389667 (rank : 116)	θ value	1.87187e-05 (rank : 130)
Query Neighborhood Hits	375	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R1W5, Q9QXH8, Q9WUP2	Gene names	Calcrl, Crlr
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

CILP2_HUMAN
NC score	0.383625 (rank : 117)	θ value	1.25267e-09 (rank : 99)
Query Neighborhood Hits	375	Target Neighborhood Hits	307	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CO8B_MOUSE
NC score	0.381360 (rank : 118)	θ value	3.77169e-06 (rank : 125)
Query Neighborhood Hits	375	Target Neighborhood Hits	224	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

GLR_HUMAN
NC score	0.380763 (rank : 119)	θ value	6.87365e-08 (rank : 117)
Query Neighborhood Hits	375	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	P47871	Gene names	GCGR
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

GLP1R_MOUSE
NC score	0.380059 (rank : 120)	θ value	0.00020696 (rank : 141)
Query Neighborhood Hits	375	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

SCTR_HUMAN
NC score	0.377103 (rank : 121)	θ value	3.19293e-05 (rank : 134)
Query Neighborhood Hits	375	Target Neighborhood Hits	70	Shared Neighborhood Hits	67
SwissProt Accessions	P47872, Q12961, Q13213	Gene names	SCTR
Domain Architecture
Description	Secretin receptor precursor (SCT-R).

GHRHR_HUMAN
NC score	0.371277 (rank : 122)	θ value	0.00134147 (rank : 148)
Query Neighborhood Hits	375	Target Neighborhood Hits	78	Shared Neighborhood Hits	74
SwissProt Accessions	Q02643, Q99863	Gene names	GHRHR
Domain Architecture
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

CI094_HUMAN
NC score	0.368257 (rank : 123)	θ value	1.06045e-08 (rank : 108)
Query Neighborhood Hits	375	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

GLP1R_HUMAN
NC score	0.366875 (rank : 124)	θ value	0.00298849 (rank : 153)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	69
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

GLR_MOUSE
NC score	0.364506 (rank : 125)	θ value	2.88788e-06 (rank : 123)
Query Neighborhood Hits	375	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

CELR1_HUMAN
NC score	0.361904 (rank : 126)	θ value	1.72781e-51 (rank : 8)
Query Neighborhood Hits	375	Target Neighborhood Hits	613	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

SCTR_MOUSE
NC score	0.361014 (rank : 127)	θ value	0.000602161 (rank : 143)
Query Neighborhood Hits	375	Target Neighborhood Hits	69	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWI2, Q80T66	Gene names	Sctr
Domain Architecture	No domain graphic available
Description	Secretin receptor precursor (SCT-R).

CO8B_HUMAN
NC score	0.358894 (rank : 128)	θ value	6.43352e-06 (rank : 127)
Query Neighborhood Hits	375	Target Neighborhood Hits	199	Shared Neighborhood Hits	78
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

GHRHR_MOUSE
NC score	0.358486 (rank : 129)	θ value	7.1131e-05 (rank : 135)
Query Neighborhood Hits	375	Target Neighborhood Hits	79	Shared Neighborhood Hits	73
SwissProt Accessions	P32082	Gene names	Ghrhr, Grfr
Domain Architecture	No domain graphic available
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

CELR1_MOUSE
NC score	0.357336 (rank : 130)	θ value	1.41672e-45 (rank : 9)
Query Neighborhood Hits	375	Target Neighborhood Hits	617	Shared Neighborhood Hits	127
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_MOUSE
NC score	0.357007 (rank : 131)	θ value	1.32601e-43 (rank : 11)
Query Neighborhood Hits	375	Target Neighborhood Hits	584	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

GIPR_HUMAN
NC score	0.354433 (rank : 132)	θ value	0.000121331 (rank : 137)
Query Neighborhood Hits	375	Target Neighborhood Hits	71	Shared Neighborhood Hits	69
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

HMCN1_HUMAN
NC score	0.351758 (rank : 133)	θ value	1.2325e-65 (rank : 7)
Query Neighborhood Hits	375	Target Neighborhood Hits	983	Shared Neighborhood Hits	135
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CELR2_HUMAN
NC score	0.349941 (rank : 134)	θ value	2.95404e-43 (rank : 12)
Query Neighborhood Hits	375	Target Neighborhood Hits	657	Shared Neighborhood Hits	126
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CO8A_MOUSE
NC score	0.343102 (rank : 135)	θ value	0.000121331 (rank : 136)
Query Neighborhood Hits	375	Target Neighborhood Hits	182	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_HUMAN
NC score	0.341076 (rank : 136)	θ value	0.00175202 (rank : 150)
Query Neighborhood Hits	375	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

GLP2R_HUMAN
NC score	0.335271 (rank : 137)	θ value	0.00665767 (rank : 158)
Query Neighborhood Hits	375	Target Neighborhood Hits	75	Shared Neighborhood Hits	70
SwissProt Accessions	O95838	Gene names	GLP2R
Domain Architecture
Description	Glucagon-like peptide 2 receptor precursor (GLP-2 receptor) (GLP-2-R) (GLP-2R).

PTHR2_HUMAN
NC score	0.335019 (rank : 138)	θ value	0.0148317 (rank : 161)
Query Neighborhood Hits	375	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P49190, Q8N429	Gene names	PTHR2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

CO7_HUMAN
NC score	0.332540 (rank : 139)	θ value	0.00134147 (rank : 146)
Query Neighborhood Hits	375	Target Neighborhood Hits	278	Shared Neighborhood Hits	82
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

GP125_HUMAN
NC score	0.330136 (rank : 140)	θ value	1.86753e-13 (rank : 76)
Query Neighborhood Hits	375	Target Neighborhood Hits	327	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

CELR3_HUMAN
NC score	0.330079 (rank : 141)	θ value	1.16164e-39 (rank : 15)
Query Neighborhood Hits	375	Target Neighborhood Hits	680	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
NC score	0.329648 (rank : 142)	θ value	2.19075e-38 (rank : 20)
Query Neighborhood Hits	375	Target Neighborhood Hits	687	Shared Neighborhood Hits	133
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

PTHR2_MOUSE
NC score	0.323408 (rank : 143)	θ value	0.0113563 (rank : 160)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

GP124_MOUSE
NC score	0.320581 (rank : 144)	θ value	2.36244e-08 (rank : 111)
Query Neighborhood Hits	375	Target Neighborhood Hits	423	Shared Neighborhood Hits	66
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CILP1_MOUSE
NC score	0.310253 (rank : 145)	θ value	2.44474e-05 (rank : 133)
Query Neighborhood Hits	375	Target Neighborhood Hits	282	Shared Neighborhood Hits	86
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

GP125_MOUSE
NC score	0.308973 (rank : 146)	θ value	1.33837e-11 (rank : 88)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP124_HUMAN
NC score	0.294864 (rank : 147)	θ value	3.77169e-06 (rank : 126)
Query Neighborhood Hits	375	Target Neighborhood Hits	304	Shared Neighborhood Hits	53
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CILP1_HUMAN
NC score	0.292445 (rank : 148)	θ value	0.000786445 (rank : 144)
Query Neighborhood Hits	375	Target Neighborhood Hits	266	Shared Neighborhood Hits	87
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

GP157_HUMAN
NC score	0.256774 (rank : 149)	θ value	0.0431538 (rank : 167)
Query Neighborhood Hits	375	Target Neighborhood Hits	93	Shared Neighborhood Hits	61
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
NC score	0.248798 (rank : 150)	θ value	0.0961366 (rank : 173)
Query Neighborhood Hits	375	Target Neighborhood Hits	78	Shared Neighborhood Hits	60
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

SPON2_HUMAN
NC score	0.198324 (rank : 151)	θ value	0.0252991 (rank : 164)
Query Neighborhood Hits	375	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON2_MOUSE
NC score	0.161010 (rank : 152)	θ value	0.163984 (rank : 182)
Query Neighborhood Hits	375	Target Neighborhood Hits	42	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

RSPO1_HUMAN
NC score	0.157066 (rank : 153)	θ value	0.0736092 (rank : 171)
Query Neighborhood Hits	375	Target Neighborhood Hits	101	Shared Neighborhood Hits	52
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

TSP3_HUMAN
NC score	0.156499 (rank : 154)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	375	Target Neighborhood Hits	250	Shared Neighborhood Hits	31
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

COMP_MOUSE
NC score	0.156429 (rank : 155)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	375	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TSP3_MOUSE
NC score	0.152926 (rank : 156)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	375	Target Neighborhood Hits	247	Shared Neighborhood Hits	31
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

COMP_HUMAN
NC score	0.150291 (rank : 157)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	375	Target Neighborhood Hits	258	Shared Neighborhood Hits	33
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TSP4_HUMAN
NC score	0.148400 (rank : 158)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	375	Target Neighborhood Hits	277	Shared Neighborhood Hits	37
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
NC score	0.147728 (rank : 159)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	375	Target Neighborhood Hits	276	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

RSPO1_MOUSE
NC score	0.136812 (rank : 160)	θ value	0.365318 (rank : 200)
Query Neighborhood Hits	375	Target Neighborhood Hits	85	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

NELL1_HUMAN
NC score	0.133227 (rank : 161)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	375	Target Neighborhood Hits	451	Shared Neighborhood Hits	58
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

WISP1_MOUSE
NC score	0.131589 (rank : 162)	θ value	0.0330416 (rank : 166)
Query Neighborhood Hits	375	Target Neighborhood Hits	123	Shared Neighborhood Hits	55
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

RSPO3_MOUSE
NC score	0.130415 (rank : 163)	θ value	0.0961366 (rank : 174)
Query Neighborhood Hits	375	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

NELL2_MOUSE
NC score	0.129919 (rank : 164)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	375	Target Neighborhood Hits	436	Shared Neighborhood Hits	48
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

RSPO3_HUMAN
NC score	0.128451 (rank : 165)	θ value	0.163984 (rank : 181)
Query Neighborhood Hits	375	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

NELL2_HUMAN
NC score	0.126001 (rank : 166)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	375	Target Neighborhood Hits	449	Shared Neighborhood Hits	48
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

WISP1_HUMAN
NC score	0.123949 (rank : 167)	θ value	0.0330416 (rank : 165)
Query Neighborhood Hits	375	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

FRAS1_MOUSE
NC score	0.122110 (rank : 168)	θ value	0.0113563 (rank : 159)
Query Neighborhood Hits	375	Target Neighborhood Hits	747	Shared Neighborhood Hits	96
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CRUM1_HUMAN
NC score	0.121073 (rank : 169)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	375	Target Neighborhood Hits	457	Shared Neighborhood Hits	57
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
NC score	0.119986 (rank : 170)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	375	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

RSPO4_MOUSE
NC score	0.117020 (rank : 171)	θ value	2.36792 (rank : 270)
Query Neighborhood Hits	375	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SUSD1_HUMAN
NC score	0.117018 (rank : 172)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	375	Target Neighborhood Hits	285	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

UROM_HUMAN
NC score	0.116239 (rank : 173)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	375	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

WISP2_MOUSE
NC score	0.115844 (rank : 174)	θ value	1.81305 (rank : 256)
Query Neighborhood Hits	375	Target Neighborhood Hits	129	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ADAM8_HUMAN
NC score	0.115272 (rank : 175)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	375	Target Neighborhood Hits	327	Shared Neighborhood Hits	74
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

FRAS1_HUMAN
NC score	0.113674 (rank : 176)	θ value	0.00134147 (rank : 147)
Query Neighborhood Hits	375	Target Neighborhood Hits	759	Shared Neighborhood Hits	87
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CRUM2_HUMAN
NC score	0.113357 (rank : 177)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	375	Target Neighborhood Hits	453	Shared Neighborhood Hits	54
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

ADAM8_MOUSE
NC score	0.112283 (rank : 178)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	375	Target Neighborhood Hits	326	Shared Neighborhood Hits	76
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

WISP2_HUMAN
NC score	0.110943 (rank : 179)	θ value	5.27518 (rank : 337)
Query Neighborhood Hits	375	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

ADA19_MOUSE
NC score	0.110626 (rank : 180)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	375	Target Neighborhood Hits	315	Shared Neighborhood Hits	74
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

LTBP4_MOUSE
NC score	0.110298 (rank : 181)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	375	Target Neighborhood Hits	607	Shared Neighborhood Hits	106
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBLN4_MOUSE
NC score	0.110150 (rank : 182)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	375	Target Neighborhood Hits	270	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

MEGF6_HUMAN
NC score	0.109556 (rank : 183)	θ value	0.62314 (rank : 209)
Query Neighborhood Hits	375	Target Neighborhood Hits	671	Shared Neighborhood Hits	84
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

FBLN4_HUMAN
NC score	0.109478 (rank : 184)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	375	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

C1QR1_HUMAN
NC score	0.108926 (rank : 185)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	375	Target Neighborhood Hits	493	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
NC score	0.108762 (rank : 186)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	375	Target Neighborhood Hits	342	Shared Neighborhood Hits	41
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

UROM_MOUSE
NC score	0.107438 (rank : 187)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	375	Target Neighborhood Hits	276	Shared Neighborhood Hits	40
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FZD3_HUMAN
NC score	0.107061 (rank : 188)	θ value	0.000158464 (rank : 139)
Query Neighborhood Hits	375	Target Neighborhood Hits	74	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD3_MOUSE
NC score	0.105886 (rank : 189)	θ value	0.00020696 (rank : 140)
Query Neighborhood Hits	375	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

DLL1_HUMAN
NC score	0.103728 (rank : 190)	θ value	3.0926 (rank : 276)
Query Neighborhood Hits	375	Target Neighborhood Hits	455	Shared Neighborhood Hits	59
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

ADA19_HUMAN
NC score	0.103110 (rank : 191)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	375	Target Neighborhood Hits	381	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

FBN1_HUMAN
NC score	0.102889 (rank : 192)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	375	Target Neighborhood Hits	557	Shared Neighborhood Hits	69
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

TRBM_MOUSE
NC score	0.102762 (rank : 193)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	375	Target Neighborhood Hits	361	Shared Neighborhood Hits	47
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_HUMAN
NC score	0.102375 (rank : 194)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	375	Target Neighborhood Hits	339	Shared Neighborhood Hits	45
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ZAN_MOUSE
NC score	0.102299 (rank : 195)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	375	Target Neighborhood Hits	808	Shared Neighborhood Hits	102
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

DLL1_MOUSE
NC score	0.101574 (rank : 196)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	375	Target Neighborhood Hits	456	Shared Neighborhood Hits	60
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

FBLN3_HUMAN
NC score	0.101527 (rank : 197)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	375	Target Neighborhood Hits	293	Shared Neighborhood Hits	40
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN1_HUMAN
NC score	0.101364 (rank : 198)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	375	Target Neighborhood Hits	324	Shared Neighborhood Hits	43
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

CO9_MOUSE
NC score	0.100797 (rank : 199)	θ value	1.38821 (rank : 229)
Query Neighborhood Hits	375	Target Neighborhood Hits	153	Shared Neighborhood Hits	38
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

ADA28_MOUSE
NC score	0.100679 (rank : 200)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	375	Target Neighborhood Hits	241	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

LTBP2_HUMAN
NC score	0.100192 (rank : 201)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	375	Target Neighborhood Hits	552	Shared Neighborhood Hits	72
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CYR61_HUMAN
NC score	0.100116 (rank : 202)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	375	Target Neighborhood Hits	159	Shared Neighborhood Hits	62
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

FBLN5_HUMAN
NC score	0.100051 (rank : 203)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBN1_MOUSE
NC score	0.099812 (rank : 204)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	375	Target Neighborhood Hits	563	Shared Neighborhood Hits	72
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP2_MOUSE
NC score	0.099766 (rank : 205)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	375	Target Neighborhood Hits	617	Shared Neighborhood Hits	76
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBLN1_MOUSE
NC score	0.099364 (rank : 206)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	43
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

NOTC3_MOUSE
NC score	0.098924 (rank : 207)	θ value	2.36792 (rank : 269)
Query Neighborhood Hits	375	Target Neighborhood Hits	975	Shared Neighborhood Hits	105
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ADA33_HUMAN
NC score	0.098862 (rank : 208)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	375	Target Neighborhood Hits	264	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA12_HUMAN
NC score	0.098620 (rank : 209)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	375	Target Neighborhood Hits	224	Shared Neighborhood Hits	53
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

FBLN3_MOUSE
NC score	0.098499 (rank : 210)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	375	Target Neighborhood Hits	279	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

LTB1L_HUMAN
NC score	0.098377 (rank : 211)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	375	Target Neighborhood Hits	553	Shared Neighborhood Hits	74
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_HUMAN
NC score	0.098189 (rank : 212)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	375	Target Neighborhood Hits	502	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ADA12_MOUSE
NC score	0.098120 (rank : 213)	θ value	3.0926 (rank : 275)
Query Neighborhood Hits	375	Target Neighborhood Hits	474	Shared Neighborhood Hits	80
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

NOTC3_HUMAN
NC score	0.098112 (rank : 214)	θ value	0.279714 (rank : 192)
Query Neighborhood Hits	375	Target Neighborhood Hits	1062	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CREL1_HUMAN
NC score	0.098079 (rank : 215)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	375	Target Neighborhood Hits	441	Shared Neighborhood Hits	47
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

RSPO4_HUMAN
NC score	0.097920 (rank : 216)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	375	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

NID1_HUMAN
NC score	0.097915 (rank : 217)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

CUBN_MOUSE
NC score	0.097582 (rank : 218)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	375	Target Neighborhood Hits	477	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBN3_HUMAN
NC score	0.097515 (rank : 219)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	375	Target Neighborhood Hits	543	Shared Neighborhood Hits	57
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

DNER_HUMAN
NC score	0.097497 (rank : 220)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	375	Target Neighborhood Hits	460	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

ADA28_HUMAN
NC score	0.097487 (rank : 221)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	375	Target Neighborhood Hits	244	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

FBN2_HUMAN
NC score	0.097450 (rank : 222)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	375	Target Neighborhood Hits	560	Shared Neighborhood Hits	70
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

STAB1_HUMAN
NC score	0.097303 (rank : 223)	θ value	8.99809 (rank : 372)
Query Neighborhood Hits	375	Target Neighborhood Hits	546	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ADAM9_MOUSE
NC score	0.097294 (rank : 224)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	375	Target Neighborhood Hits	325	Shared Neighborhood Hits	74
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

STAB2_MOUSE
NC score	0.097267 (rank : 225)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	375	Target Neighborhood Hits	528	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

DLL4_HUMAN
NC score	0.097218 (rank : 226)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	375	Target Neighborhood Hits	435	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FBN2_MOUSE
NC score	0.097197 (rank : 227)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	375	Target Neighborhood Hits	549	Shared Neighborhood Hits	70
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBLN5_MOUSE
NC score	0.097071 (rank : 228)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	375	Target Neighborhood Hits	317	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBLN2_MOUSE
NC score	0.096993 (rank : 229)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	375	Target Neighborhood Hits	505	Shared Neighborhood Hits	71
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

NID2_HUMAN
NC score	0.096223 (rank : 230)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	375	Target Neighborhood Hits	456	Shared Neighborhood Hits	51
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LTB1L_MOUSE
NC score	0.096191 (rank : 231)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	375	Target Neighborhood Hits	514	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.096016 (rank : 232)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	375	Target Neighborhood Hits	502	Shared Neighborhood Hits	57
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_MOUSE
NC score	0.095489 (rank : 233)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	375	Target Neighborhood Hits	475	Shared Neighborhood Hits	62
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NID2_MOUSE
NC score	0.095423 (rank : 234)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	375	Target Neighborhood Hits	338	Shared Neighborhood Hits	41
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

CREL1_MOUSE
NC score	0.095419 (rank : 235)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	375	Target Neighborhood Hits	524	Shared Neighborhood Hits	49
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

JAG1_HUMAN
NC score	0.095338 (rank : 236)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	375	Target Neighborhood Hits	514	Shared Neighborhood Hits	60
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

ADEC1_HUMAN
NC score	0.095301 (rank : 237)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	375	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

PROS_HUMAN
NC score	0.095127 (rank : 238)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	375	Target Neighborhood Hits	340	Shared Neighborhood Hits	38
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

JAG1_MOUSE
NC score	0.095118 (rank : 239)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	375	Target Neighborhood Hits	518	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NID1_MOUSE
NC score	0.095024 (rank : 240)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	375	Target Neighborhood Hits	335	Shared Neighborhood Hits	37
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LTB1S_MOUSE
NC score	0.094819 (rank : 241)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	375	Target Neighborhood Hits	479	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PROS_MOUSE
NC score	0.094795 (rank : 242)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	375	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

EGF_HUMAN
NC score	0.094693 (rank : 243)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	375	Target Neighborhood Hits	343	Shared Neighborhood Hits	44
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

DNER_MOUSE
NC score	0.094174 (rank : 244)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	375	Target Neighborhood Hits	413	Shared Neighborhood Hits	60
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLL4_MOUSE
NC score	0.093986 (rank : 245)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	375	Target Neighborhood Hits	440	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOV_HUMAN
NC score	0.093622 (rank : 246)	θ value	0.47712 (rank : 204)
Query Neighborhood Hits	375	Target Neighborhood Hits	128	Shared Neighborhood Hits	49
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOTC2_HUMAN
NC score	0.093558 (rank : 247)	θ value	0.21417 (rank : 186)
Query Neighborhood Hits	375	Target Neighborhood Hits	1113	Shared Neighborhood Hits	102
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOV_MOUSE
NC score	0.093332 (rank : 248)	θ value	1.81305 (rank : 250)
Query Neighborhood Hits	375	Target Neighborhood Hits	130	Shared Neighborhood Hits	53
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

ADA15_HUMAN
NC score	0.092978 (rank : 249)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	375	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

EGF_MOUSE
NC score	0.092937 (rank : 250)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	375	Target Neighborhood Hits	358	Shared Neighborhood Hits	44
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

DLK_HUMAN
NC score	0.092697 (rank : 251)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	375	Target Neighborhood Hits	401	Shared Neighborhood Hits	48
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

JAG2_HUMAN
NC score	0.092547 (rank : 252)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	375	Target Neighborhood Hits	491	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

FBLN2_HUMAN
NC score	0.092155 (rank : 253)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	375	Target Neighborhood Hits	392	Shared Neighborhood Hits	48
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

NOTC4_HUMAN
NC score	0.091933 (rank : 254)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	375	Target Neighborhood Hits	905	Shared Neighborhood Hits	81
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DLK_MOUSE
NC score	0.091883 (rank : 255)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	375	Target Neighborhood Hits	374	Shared Neighborhood Hits	51
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

NOTC1_MOUSE
NC score	0.091682 (rank : 256)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	375	Target Neighborhood Hits	916	Shared Neighborhood Hits	79
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FZD6_HUMAN
NC score	0.091619 (rank : 257)	θ value	0.00509761 (rank : 157)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

SCUB3_MOUSE
NC score	0.091508 (rank : 258)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	375	Target Neighborhood Hits	442	Shared Neighborhood Hits	47
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NOTC1_HUMAN
NC score	0.091362 (rank : 259)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	375	Target Neighborhood Hits	906	Shared Neighborhood Hits	84
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SCUB3_HUMAN
NC score	0.091307 (rank : 260)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	375	Target Neighborhood Hits	428	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NOTC2_MOUSE
NC score	0.091148 (rank : 261)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	375	Target Neighborhood Hits	1069	Shared Neighborhood Hits	97
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_MOUSE
NC score	0.090844 (rank : 262)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	375	Target Neighborhood Hits	872	Shared Neighborhood Hits	71
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

CUBN_HUMAN
NC score	0.090415 (rank : 263)	θ value	4.03905 (rank : 302)
Query Neighborhood Hits	375	Target Neighborhood Hits	482	Shared Neighborhood Hits	53
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

JAG2_MOUSE
NC score	0.090404 (rank : 264)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	375	Target Neighborhood Hits	504	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

AGRIN_HUMAN
NC score	0.090336 (rank : 265)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	375	Target Neighborhood Hits	582	Shared Neighborhood Hits	78
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

STAB2_HUMAN
NC score	0.090248 (rank : 266)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	375	Target Neighborhood Hits	534	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ADA33_MOUSE
NC score	0.090008 (rank : 267)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	375	Target Neighborhood Hits	231	Shared Neighborhood Hits	51
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

STAB1_MOUSE
NC score	0.089984 (rank : 268)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	375	Target Neighborhood Hits	566	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

ADAM7_MOUSE
NC score	0.089775 (rank : 269)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	375	Target Neighborhood Hits	200	Shared Neighborhood Hits	49
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

DLL3_MOUSE
NC score	0.089751 (rank : 270)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	375	Target Neighborhood Hits	399	Shared Neighborhood Hits	53
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

GAS6_MOUSE
NC score	0.088750 (rank : 271)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	375	Target Neighborhood Hits	343	Shared Neighborhood Hits	40
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FZD6_MOUSE
NC score	0.088477 (rank : 272)	θ value	0.00175202 (rank : 151)
Query Neighborhood Hits	375	Target Neighborhood Hits	135	Shared Neighborhood Hits	33
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

GAS6_HUMAN
NC score	0.088413 (rank : 273)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	375	Target Neighborhood Hits	348	Shared Neighborhood Hits	40
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ADAM7_HUMAN
NC score	0.087968 (rank : 274)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	375	Target Neighborhood Hits	221	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM9_HUMAN
NC score	0.087435 (rank : 275)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	375	Target Neighborhood Hits	243	Shared Neighborhood Hits	52
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

SREC_HUMAN
NC score	0.086908 (rank : 276)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	375	Target Neighborhood Hits	645	Shared Neighborhood Hits	78
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

RSPO2_HUMAN
NC score	0.086187 (rank : 277)	θ value	1.38821 (rank : 239)
Query Neighborhood Hits	375	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

FATH_HUMAN
NC score	0.085803 (rank : 278)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	375	Target Neighborhood Hits	570	Shared Neighborhood Hits	50
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

DLL3_HUMAN
NC score	0.085638 (rank : 279)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	375	Target Neighborhood Hits	419	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

SLIT2_HUMAN
NC score	0.085612 (rank : 280)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	375	Target Neighborhood Hits	708	Shared Neighborhood Hits	58
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SREC2_HUMAN
NC score	0.085357 (rank : 281)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	375	Target Neighborhood Hits	645	Shared Neighborhood Hits	102
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

EGFL9_MOUSE
NC score	0.084868 (rank : 282)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	375	Target Neighborhood Hits	379	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

CO9_HUMAN
NC score	0.084623 (rank : 283)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	375	Target Neighborhood Hits	147	Shared Neighborhood Hits	30
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

ZAN_HUMAN
NC score	0.084395 (rank : 284)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	375	Target Neighborhood Hits	679	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CYR61_MOUSE
NC score	0.083905 (rank : 285)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	375	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

EGFL7_HUMAN
NC score	0.083695 (rank : 286)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	375	Target Neighborhood Hits	325	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

ADA15_MOUSE
NC score	0.083502 (rank : 287)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	375	Target Neighborhood Hits	324	Shared Neighborhood Hits	72
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

EGFL9_HUMAN
NC score	0.083028 (rank : 288)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	375	Target Neighborhood Hits	365	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

MUC2_HUMAN
NC score	0.082732 (rank : 289)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	375	Target Neighborhood Hits	906	Shared Neighborhood Hits	125
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SLIT1_MOUSE
NC score	0.082087 (rank : 290)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	375	Target Neighborhood Hits	715	Shared Neighborhood Hits	59
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

KR106_HUMAN
NC score	0.082082 (rank : 291)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	375	Target Neighborhood Hits	347	Shared Neighborhood Hits	55
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

MUC5B_HUMAN
NC score	0.081480 (rank : 292)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	375	Target Neighborhood Hits	1020	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SLIT2_MOUSE
NC score	0.081374 (rank : 293)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	375	Target Neighborhood Hits	684	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_MOUSE
NC score	0.081348 (rank : 294)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	375	Target Neighborhood Hits	700	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

MEGF8_HUMAN
NC score	0.081247 (rank : 295)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	375	Target Neighborhood Hits	528	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SREC2_MOUSE
NC score	0.081226 (rank : 296)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	375	Target Neighborhood Hits	605	Shared Neighborhood Hits	93
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KR414_HUMAN
NC score	0.080976 (rank : 297)	θ value	6.88961 (rank : 347)
Query Neighborhood Hits	375	Target Neighborhood Hits	199	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

NRX2A_HUMAN
NC score	0.080396 (rank : 298)	θ value	0.00298849 (rank : 154)
Query Neighborhood Hits	375	Target Neighborhood Hits	614	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

SLIT1_HUMAN
NC score	0.080011 (rank : 299)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	375	Target Neighborhood Hits	700	Shared Neighborhood Hits	55
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT3_HUMAN
NC score	0.079989 (rank : 300)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	375	Target Neighborhood Hits	682	Shared Neighborhood Hits	53
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

RSPO2_MOUSE
NC score	0.079598 (rank : 301)	θ value	0.62314 (rank : 212)
Query Neighborhood Hits	375	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

MEGF8_MOUSE
NC score	0.078337 (rank : 302)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	375	Target Neighborhood Hits	520	Shared Neighborhood Hits	51
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LRP1_HUMAN
NC score	0.078278 (rank : 303)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	375	Target Neighborhood Hits	617	Shared Neighborhood Hits	71
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

ADEC1_MOUSE
NC score	0.077651 (rank : 304)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	375	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

KR104_HUMAN
NC score	0.077524 (rank : 305)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	375	Target Neighborhood Hits	313	Shared Neighborhood Hits	51
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

ADM1B_MOUSE
NC score	0.077521 (rank : 306)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	375	Target Neighborhood Hits	236	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA21_MOUSE
NC score	0.076978 (rank : 307)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	375	Target Neighborhood Hits	172	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

MEGF9_HUMAN
NC score	0.076705 (rank : 308)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	375	Target Neighborhood Hits	557	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ADA22_HUMAN
NC score	0.076378 (rank : 309)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	375	Target Neighborhood Hits	211	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

LRP2_HUMAN
NC score	0.076343 (rank : 310)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	375	Target Neighborhood Hits	573	Shared Neighborhood Hits	64
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP1B_HUMAN
NC score	0.076125 (rank : 311)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	375	Target Neighborhood Hits	602	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ADM1A_MOUSE
NC score	0.075697 (rank : 312)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	375	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

MUCDL_HUMAN
NC score	0.075632 (rank : 313)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	375	Target Neighborhood Hits	777	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ADA23_MOUSE
NC score	0.075151 (rank : 314)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	375	Target Neighborhood Hits	245	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

TENX_HUMAN
NC score	0.074300 (rank : 315)	θ value	0.47712 (rank : 205)
Query Neighborhood Hits	375	Target Neighborhood Hits	789	Shared Neighborhood Hits	84
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LRP1B_MOUSE
NC score	0.074257 (rank : 316)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	375	Target Neighborhood Hits	606	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KR107_HUMAN
NC score	0.073870 (rank : 317)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	375	Target Neighborhood Hits	330	Shared Neighborhood Hits	48
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

ADA24_MOUSE
NC score	0.073521 (rank : 318)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	375	Target Neighborhood Hits	230	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

KR101_HUMAN
NC score	0.073490 (rank : 319)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	375	Target Neighborhood Hits	261	Shared Neighborhood Hits	45
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

ADA22_MOUSE
NC score	0.072947 (rank : 320)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	375	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

EGFL7_MOUSE
NC score	0.072866 (rank : 321)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	375	Target Neighborhood Hits	287	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

PGBM_HUMAN
NC score	0.072840 (rank : 322)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	375	Target Neighborhood Hits	1113	Shared Neighborhood Hits	80
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ADA29_HUMAN
NC score	0.072280 (rank : 323)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	375	Target Neighborhood Hits	247	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

WISP3_HUMAN
NC score	0.072139 (rank : 324)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	375	Target Neighborhood Hits	87	Shared Neighborhood Hits	42
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

PGBM_MOUSE
NC score	0.071972 (rank : 325)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	375	Target Neighborhood Hits	1073	Shared Neighborhood Hits	71
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ADA23_HUMAN
NC score	0.071712 (rank : 326)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	375	Target Neighborhood Hits	235	Shared Neighborhood Hits	49
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CD248_MOUSE
NC score	0.070837 (rank : 327)	θ value	1.38821 (rank : 228)
Query Neighborhood Hits	375	Target Neighborhood Hits	578	Shared Neighborhood Hits	73
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FAT2_HUMAN
NC score	0.070633 (rank : 328)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	375	Target Neighborhood Hits	507	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

PCD15_HUMAN
NC score	0.070580 (rank : 329)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	375	Target Neighborhood Hits	289	Shared Neighborhood Hits	57
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

CSPG3_MOUSE
NC score	0.070528 (rank : 330)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	375	Target Neighborhood Hits	657	Shared Neighborhood Hits	75
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KRA51_HUMAN
NC score	0.069807 (rank : 331)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	375	Target Neighborhood Hits	288	Shared Neighborhood Hits	47
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

PCD15_MOUSE
NC score	0.069577 (rank : 332)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	375	Target Neighborhood Hits	262	Shared Neighborhood Hits	51
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

ADA21_HUMAN
NC score	0.069473 (rank : 333)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	375	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA25_MOUSE
NC score	0.069355 (rank : 334)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	375	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

MATN2_HUMAN
NC score	0.069321 (rank : 335)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	375	Target Neighborhood Hits	365	Shared Neighborhood Hits	40
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

CTGF_MOUSE
NC score	0.069239 (rank : 336)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	375	Target Neighborhood Hits	124	Shared Neighborhood Hits	51
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CRIM1_HUMAN
NC score	0.068954 (rank : 337)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	375	Target Neighborhood Hits	362	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ADA11_MOUSE
NC score	0.068944 (rank : 338)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	375	Target Neighborhood Hits	263	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

NRX3A_HUMAN
NC score	0.068847 (rank : 339)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	375	Target Neighborhood Hits	164	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

AD26A_MOUSE
NC score	0.068608 (rank : 340)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	375	Target Neighborhood Hits	165	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

CTGF_HUMAN
NC score	0.068384 (rank : 341)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	375	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

NRX1A_MOUSE
NC score	0.067690 (rank : 342)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	375	Target Neighborhood Hits	164	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

KR102_HUMAN
NC score	0.067584 (rank : 343)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	375	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

NRX1A_HUMAN
NC score	0.067376 (rank : 344)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	375	Target Neighborhood Hits	170	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

EDIL3_MOUSE
NC score	0.067375 (rank : 345)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	375	Target Neighborhood Hits	317	Shared Neighborhood Hits	36
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_HUMAN
NC score	0.067290 (rank : 346)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	375	Target Neighborhood Hits	292	Shared Neighborhood Hits	35
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CAD23_MOUSE
NC score	0.067095 (rank : 347)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	375	Target Neighborhood Hits	208	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_HUMAN
NC score	0.066662 (rank : 348)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	375	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

MEGF9_MOUSE
NC score	0.066482 (rank : 349)	θ value	1.81305 (rank : 248)
Query Neighborhood Hits	375	Target Neighborhood Hits	896	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MATN4_HUMAN
NC score	0.065615 (rank : 350)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	375	Target Neighborhood Hits	287	Shared Neighborhood Hits	37
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

LDLR_HUMAN
NC score	0.065571 (rank : 351)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	375	Target Neighborhood Hits	375	Shared Neighborhood Hits	51
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CSPG2_MOUSE
NC score	0.065329 (rank : 352)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	375	Target Neighborhood Hits	711	Shared Neighborhood Hits	69
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
NC score	0.065288 (rank : 353)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	375	Target Neighborhood Hits	676	Shared Neighborhood Hits	67
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PCD16_HUMAN
NC score	0.064497 (rank : 354)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	375	Target Neighborhood Hits	245	Shared Neighborhood Hits	21
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PRP2_MOUSE
NC score	0.064326 (rank : 355)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	375	Target Neighborhood Hits	347	Shared Neighborhood Hits	102
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PCSK5_MOUSE
NC score	0.064172 (rank : 356)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	375	Target Neighborhood Hits	613	Shared Neighborhood Hits	69
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

MATN2_MOUSE
NC score	0.063849 (rank : 357)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	375	Target Neighborhood Hits	356	Shared Neighborhood Hits	39
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

PCDLK_HUMAN
NC score	0.063824 (rank : 358)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	375	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

MYOC_MOUSE
NC score	0.063359 (rank : 359)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	375	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

WIF1_MOUSE
NC score	0.063086 (rank : 360)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	375	Target Neighborhood Hits	393	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_HUMAN
NC score	0.062984 (rank : 361)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	375	Target Neighborhood Hits	392	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CD248_HUMAN
NC score	0.062937 (rank : 362)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	375	Target Neighborhood Hits	679	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

OLFL1_HUMAN
NC score	0.062223 (rank : 363)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	375	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWY5	Gene names	OLFML1
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 1 precursor.

LRP8_MOUSE
NC score	0.062158 (rank : 364)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	375	Target Neighborhood Hits	385	Shared Neighborhood Hits	52
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SEM6C_MOUSE
NC score	0.061896 (rank : 365)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	375	Target Neighborhood Hits	352	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

CSPG2_HUMAN
NC score	0.061849 (rank : 366)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	375	Target Neighborhood Hits	681	Shared Neighborhood Hits	58
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

LAMA5_MOUSE
NC score	0.061514 (rank : 367)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	375	Target Neighborhood Hits	828	Shared Neighborhood Hits	62
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

PRP1_HUMAN
NC score	0.061484 (rank : 368)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	375	Target Neighborhood Hits	385	Shared Neighborhood Hits	99
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

LAMA5_HUMAN
NC score	0.061433 (rank : 369)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	375	Target Neighborhood Hits	976	Shared Neighborhood Hits	68
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MATN3_MOUSE
NC score	0.061405 (rank : 370)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	375	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

SEM6C_HUMAN
NC score	0.060931 (rank : 371)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	375	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6B_HUMAN
NC score	0.060879 (rank : 372)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	375	Target Neighborhood Hits	187	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

LDLR_MOUSE
NC score	0.060877 (rank : 373)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	375	Target Neighborhood Hits	382	Shared Neighborhood Hits	50
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MATN3_HUMAN
NC score	0.060785 (rank : 374)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	375	Target Neighborhood Hits	268	Shared Neighborhood Hits	30
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

KR109_HUMAN
NC score	0.060718 (rank : 375)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	375	Target Neighborhood Hits	226	Shared Neighborhood Hits	38
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

ADAM2_MOUSE
NC score	0.060492 (rank : 376)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	375	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

KR412_HUMAN
NC score	0.060474 (rank : 377)	θ value	2.36792 (rank : 267)
Query Neighborhood Hits	375	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

EGFL8_MOUSE
NC score	0.060328 (rank : 378)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	375	Target Neighborhood Hits	266	Shared Neighborhood Hits	30
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

BMPER_HUMAN
NC score	0.060268 (rank : 379)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	375	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

LAMB2_HUMAN
NC score	0.060172 (rank : 380)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	375	Target Neighborhood Hits	692	Shared Neighborhood Hits	44
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

VWF_HUMAN
NC score	0.059993 (rank : 381)	θ value	4.03905 (rank : 315)
Query Neighborhood Hits	375	Target Neighborhood Hits	396	Shared Neighborhood Hits	57
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WASIP_MOUSE
NC score	0.059664 (rank : 382)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	375	Target Neighborhood Hits	392	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ADA11_HUMAN
NC score	0.059607 (rank : 383)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	375	Target Neighborhood Hits	259	Shared Neighborhood Hits	53
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

LAMC3_MOUSE
NC score	0.059561 (rank : 384)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	375	Target Neighborhood Hits	624	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LYAM2_HUMAN
NC score	0.059542 (rank : 385)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	375	Target Neighborhood Hits	394	Shared Neighborhood Hits	44
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NOE2_HUMAN
NC score	0.059527 (rank : 386)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	375	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O95897, Q6IMJ3, Q96FC2	Gene names	OLFM2, NOE2
Domain Architecture
Description	Noelin-2 precursor (Olfactomedin-2).

NOE2_MOUSE
NC score	0.059494 (rank : 387)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	375	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM13	Gene names	Olfm2
Domain Architecture	No domain graphic available
Description	Noelin-2 precursor (Olfactomedin-2).

LRP8_HUMAN
NC score	0.059454 (rank : 388)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	375	Target Neighborhood Hits	346	Shared Neighborhood Hits	52
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MUCDL_MOUSE
NC score	0.059342 (rank : 389)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	375	Target Neighborhood Hits	461	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

FZD1_MOUSE
NC score	0.059296 (rank : 390)	θ value	0.365318 (rank : 196)
Query Neighborhood Hits	375	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

SEM6B_MOUSE
NC score	0.059135 (rank : 391)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	375	Target Neighborhood Hits	200	Shared Neighborhood Hits	15
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

OLFL3_MOUSE
NC score	0.058974 (rank : 392)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	375	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BK62, Q3V2F2, Q8C1T0, Q99K37	Gene names	Olfml3
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 3 precursor.

OLFL3_HUMAN
NC score	0.058956 (rank : 393)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	375	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRN5, Q53FR1, Q53HV9, Q5SQL6, Q69AX9, Q8NBJ2	Gene names	OLFML3
Domain Architecture
Description	Olfactomedin-like protein 3 precursor (HNOEL-iso) (hOLF44).

LRP4_HUMAN
NC score	0.058781 (rank : 394)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	375	Target Neighborhood Hits	355	Shared Neighborhood Hits	45
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
NC score	0.058550 (rank : 395)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	375	Target Neighborhood Hits	351	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

CAD17_MOUSE
NC score	0.058359 (rank : 396)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	375	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

SEM6D_MOUSE
NC score	0.057976 (rank : 397)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	375	Target Neighborhood Hits	161	Shared Neighborhood Hits	17
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

NOE3_MOUSE
NC score	0.057731 (rank : 398)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	375	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	P63056, Q8BKV2, Q8BLL6, Q8QZW0, Q8R4K3, Q8R4K4	Gene names	Olfm3, Noe3
Domain Architecture	No domain graphic available
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

NOE3_HUMAN
NC score	0.057723 (rank : 399)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	375	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PB7, Q8TBG1, Q96PB2, Q96PB3, Q96PB4, Q96PB5, Q96PB6	Gene names	OLFM3, NOE3
Domain Architecture
Description	Noelin-3 precursor (Olfactomedin-3) (Optimedin).

SEM6D_HUMAN
NC score	0.057380 (rank : 400)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	375	Target Neighborhood Hits	169	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6A_MOUSE
NC score	0.057365 (rank : 401)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	375	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM4C_HUMAN
NC score	0.057045 (rank : 402)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	375	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

PCDH1_HUMAN
NC score	0.056841 (rank : 403)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	375	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

SEM6A_HUMAN
NC score	0.056840 (rank : 404)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	375	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

CAD17_HUMAN
NC score	0.056341 (rank : 405)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	375	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

VLDLR_HUMAN
NC score	0.055997 (rank : 406)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	375	Target Neighborhood Hits	383	Shared Neighborhood Hits	43
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

PCDH7_HUMAN
NC score	0.055826 (rank : 407)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	375	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

NOE1_MOUSE
NC score	0.055757 (rank : 408)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	375	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	O88998, O35429, O88999, Q91XK8, Q9QWQ9, Q9QWR0	Gene names	Olfm1, Noe1, Noel, Noel1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin).

SEM3C_MOUSE
NC score	0.055718 (rank : 409)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	375	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3C_HUMAN
NC score	0.055711 (rank : 410)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	375	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM4A_HUMAN
NC score	0.055393 (rank : 411)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	375	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

NOE1_HUMAN
NC score	0.055186 (rank : 412)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	375	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q99784, Q969S7, Q99452	Gene names	OLFM1, NOE1, NOEL1
Domain Architecture
Description	Noelin precursor (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1).

MUC7_HUMAN
NC score	0.055177 (rank : 413)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	375	Target Neighborhood Hits	538	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PCDH9_HUMAN
NC score	0.055170 (rank : 414)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	375	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

PC11Y_HUMAN
NC score	0.055152 (rank : 415)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	375	Target Neighborhood Hits	205	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

SEM4C_MOUSE
NC score	0.055140 (rank : 416)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	375	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM3F_HUMAN
NC score	0.055038 (rank : 417)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	375	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

PRR12_HUMAN
NC score	0.054910 (rank : 418)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	375	Target Neighborhood Hits	460	Shared Neighborhood Hits	108
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PCD20_HUMAN
NC score	0.054841 (rank : 419)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	375	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N6Y1, Q8NDN4, Q9NRT9	Gene names	PCDH20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor (Protocadherin-13).

BMPER_MOUSE
NC score	0.054818 (rank : 420)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	375	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

PCD20_MOUSE
NC score	0.054818 (rank : 421)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	375	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BIZ0, Q8BIV2	Gene names	Pcdh20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor.

PC11X_HUMAN
NC score	0.054807 (rank : 422)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	375	Target Neighborhood Hits	199	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

SEM4A_MOUSE
NC score	0.054775 (rank : 423)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	375	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

PERF_HUMAN
NC score	0.054702 (rank : 424)	θ value	1.06291 (rank : 224)
Query Neighborhood Hits	375	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

PROZ_HUMAN
NC score	0.054673 (rank : 425)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	375	Target Neighborhood Hits	422	Shared Neighborhood Hits	34
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

VLDLR_MOUSE
NC score	0.054656 (rank : 426)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	375	Target Neighborhood Hits	360	Shared Neighborhood Hits	42
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CAD16_HUMAN
NC score	0.054651 (rank : 427)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	375	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

KRA92_HUMAN
NC score	0.054649 (rank : 428)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	375	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

CAD16_MOUSE
NC score	0.054573 (rank : 429)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	375	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

ADA32_HUMAN
NC score	0.054445 (rank : 430)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	375	Target Neighborhood Hits	216	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA17_MOUSE
NC score	0.054421 (rank : 431)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	375	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

SEM4D_HUMAN
NC score	0.054207 (rank : 432)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	375	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM4B_HUMAN
NC score	0.053901 (rank : 433)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	375	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

FZD5_HUMAN
NC score	0.053857 (rank : 434)	θ value	0.21417 (rank : 185)
Query Neighborhood Hits	375	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

SEM4B_MOUSE
NC score	0.053768 (rank : 435)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	375	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

ROBO4_MOUSE
NC score	0.053691 (rank : 436)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	375	Target Neighborhood Hits	358	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

MYOC_HUMAN
NC score	0.053577 (rank : 437)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	375	Target Neighborhood Hits	489	Shared Neighborhood Hits	5
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

KRA58_HUMAN
NC score	0.053530 (rank : 438)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	375	Target Neighborhood Hits	324	Shared Neighborhood Hits	38
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ADA10_HUMAN
NC score	0.053525 (rank : 439)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	375	Target Neighborhood Hits	189	Shared Neighborhood Hits	43
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

WASIP_HUMAN
NC score	0.053390 (rank : 440)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	375	Target Neighborhood Hits	458	Shared Neighborhood Hits	106
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PROZ_MOUSE
NC score	0.053283 (rank : 441)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	375	Target Neighborhood Hits	410	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

ADA10_MOUSE
NC score	0.053275 (rank : 442)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	375	Target Neighborhood Hits	194	Shared Neighborhood Hits	42
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

MUC13_MOUSE
NC score	0.053229 (rank : 443)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	375	Target Neighborhood Hits	447	Shared Neighborhood Hits	60
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ROBO4_HUMAN
NC score	0.053042 (rank : 444)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	375	Target Neighborhood Hits	364	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

LAMC3_HUMAN
NC score	0.053037 (rank : 445)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	375	Target Neighborhood Hits	588	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA1_MOUSE
NC score	0.052958 (rank : 446)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	375	Target Neighborhood Hits	838	Shared Neighborhood Hits	48
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KRA59_HUMAN
NC score	0.052940 (rank : 447)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	375	Target Neighborhood Hits	310	Shared Neighborhood Hits	41
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMB2_MOUSE
NC score	0.052782 (rank : 448)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	375	Target Neighborhood Hits	722	Shared Neighborhood Hits	44
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

ADA32_MOUSE
NC score	0.052770 (rank : 449)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	375	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

SEM4D_MOUSE
NC score	0.052705 (rank : 450)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	375	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SEM3F_MOUSE
NC score	0.052637 (rank : 451)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	375	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM4F_MOUSE
NC score	0.052613 (rank : 452)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	375	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

KR105_HUMAN
NC score	0.052585 (rank : 453)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	375	Target Neighborhood Hits	271	Shared Neighborhood Hits	41
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

TENA_HUMAN
NC score	0.052470 (rank : 454)	θ value	1.81305 (rank : 254)
Query Neighborhood Hits	375	Target Neighborhood Hits	631	Shared Neighborhood Hits	56
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

ADA17_HUMAN
NC score	0.052446 (rank : 455)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	375	Target Neighborhood Hits	223	Shared Neighborhood Hits	44
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

LAMB3_MOUSE
NC score	0.052430 (rank : 456)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	375	Target Neighborhood Hits	444	Shared Neighborhood Hits	40
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

USH2A_MOUSE
NC score	0.052272 (rank : 457)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	375	Target Neighborhood Hits	626	Shared Neighborhood Hits	50
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ADA20_HUMAN
NC score	0.052256 (rank : 458)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	375	Target Neighborhood Hits	143	Shared Neighborhood Hits	40
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

PRB4S_HUMAN
NC score	0.052174 (rank : 459)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	375	Target Neighborhood Hits	330	Shared Neighborhood Hits	84
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

FZD5_MOUSE
NC score	0.052123 (rank : 460)	θ value	0.365318 (rank : 197)
Query Neighborhood Hits	375	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

SEM4F_HUMAN
NC score	0.051975 (rank : 461)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	375	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

GP155_HUMAN
NC score	0.051948 (rank : 462)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	375	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

LAMA2_HUMAN
NC score	0.051908 (rank : 463)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	375	Target Neighborhood Hits	1092	Shared Neighborhood Hits	54
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KRA98_HUMAN
NC score	0.051756 (rank : 464)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	375	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

SEM3A_HUMAN
NC score	0.051683 (rank : 465)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	375	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

SEM3B_HUMAN
NC score	0.051671 (rank : 466)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

ITB5_MOUSE
NC score	0.051662 (rank : 467)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	375	Target Neighborhood Hits	329	Shared Neighborhood Hits	40
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

EGFL8_HUMAN
NC score	0.051494 (rank : 468)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	375	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

SEM3E_MOUSE
NC score	0.051439 (rank : 469)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	375	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

ITB5_HUMAN
NC score	0.051415 (rank : 470)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	375	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

KRA53_HUMAN
NC score	0.051350 (rank : 471)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	375	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

ADA18_MOUSE
NC score	0.051337 (rank : 472)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	375	Target Neighborhood Hits	227	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

LAMB3_HUMAN
NC score	0.051281 (rank : 473)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	375	Target Neighborhood Hits	461	Shared Neighborhood Hits	33
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMA1_HUMAN
NC score	0.051225 (rank : 474)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	375	Target Neighborhood Hits	804	Shared Neighborhood Hits	50
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

SEM3E_HUMAN
NC score	0.051166 (rank : 475)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	375	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

LAMC1_HUMAN
NC score	0.051117 (rank : 476)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	375	Target Neighborhood Hits	922	Shared Neighborhood Hits	52
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SEM3A_MOUSE
NC score	0.050994 (rank : 477)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	375	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

LAMA2_MOUSE
NC score	0.050843 (rank : 478)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	375	Target Neighborhood Hits	1198	Shared Neighborhood Hits	53
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LYAM2_MOUSE
NC score	0.050786 (rank : 479)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	375	Target Neighborhood Hits	420	Shared Neighborhood Hits	43
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

SEM4G_MOUSE
NC score	0.050323 (rank : 480)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	375	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SEM3B_MOUSE
NC score	0.050290 (rank : 481)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	375	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

PRR13_HUMAN
NC score	0.050276 (rank : 482)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	375	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SEM3D_HUMAN
NC score	0.050107 (rank : 483)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	375	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

CU063_HUMAN
NC score	0.050087 (rank : 484)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	375	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P58658, Q8IXZ0	Gene names	C21orf63
Domain Architecture
Description	Protein C21orf63 precursor (SUE21).

VWF_MOUSE
NC score	0.050075 (rank : 485)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	375	Target Neighborhood Hits	381	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KR108_HUMAN
NC score	0.050042 (rank : 486)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	375	Target Neighborhood Hits	226	Shared Neighborhood Hits	36
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

FZD1_HUMAN
NC score	0.049370 (rank : 487)	θ value	3.0926 (rank : 278)
Query Neighborhood Hits	375	Target Neighborhood Hits	62	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD9_MOUSE
NC score	0.048060 (rank : 488)	θ value	2.36792 (rank : 263)
Query Neighborhood Hits	375	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

TENA_MOUSE
NC score	0.047103 (rank : 489)	θ value	6.88961 (rank : 353)
Query Neighborhood Hits	375	Target Neighborhood Hits	596	Shared Neighborhood Hits	51
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

LAMA3_MOUSE
NC score	0.046582 (rank : 490)	θ value	3.0926 (rank : 283)
Query Neighborhood Hits	375	Target Neighborhood Hits	859	Shared Neighborhood Hits	55
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

FZD9_HUMAN
NC score	0.045563 (rank : 491)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	375	Target Neighborhood Hits	63	Shared Neighborhood Hits	28
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

MKL1_MOUSE
NC score	0.043948 (rank : 492)	θ value	0.00228821 (rank : 152)
Query Neighborhood Hits	375	Target Neighborhood Hits	667	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

FZD7_MOUSE
NC score	0.043813 (rank : 493)	θ value	4.03905 (rank : 304)
Query Neighborhood Hits	375	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

HHIP_HUMAN
NC score	0.043462 (rank : 494)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	375	Target Neighborhood Hits	249	Shared Neighborhood Hits	33
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

NRX2B_HUMAN
NC score	0.041875 (rank : 495)	θ value	0.00298849 (rank : 155)
Query Neighborhood Hits	375	Target Neighborhood Hits	481	Shared Neighborhood Hits	47
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PCLO_HUMAN
NC score	0.041828 (rank : 496)	θ value	0.0563607 (rank : 169)
Query Neighborhood Hits	375	Target Neighborhood Hits	2046	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

FZD7_HUMAN
NC score	0.041416 (rank : 497)	θ value	2.36792 (rank : 262)
Query Neighborhood Hits	375	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

NACAM_MOUSE
NC score	0.040564 (rank : 498)	θ value	0.163984 (rank : 180)
Query Neighborhood Hits	375	Target Neighborhood Hits	1866	Shared Neighborhood Hits	127
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ATX7_MOUSE
NC score	0.040112 (rank : 499)	θ value	0.0961366 (rank : 172)
Query Neighborhood Hits	375	Target Neighborhood Hits	328	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

KRA42_HUMAN
NC score	0.039338 (rank : 500)	θ value	4.03905 (rank : 310)
Query Neighborhood Hits	375	Target Neighborhood Hits	149	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

FA47B_HUMAN
NC score	0.038332 (rank : 501)	θ value	0.21417 (rank : 184)
Query Neighborhood Hits	375	Target Neighborhood Hits	431	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

MUC1_HUMAN
NC score	0.038281 (rank : 502)	θ value	0.000270298 (rank : 142)
Query Neighborhood Hits	375	Target Neighborhood Hits	975	Shared Neighborhood Hits	83
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SON_MOUSE
NC score	0.038192 (rank : 503)	θ value	1.06291 (rank : 226)
Query Neighborhood Hits	375	Target Neighborhood Hits	957	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

FA47A_HUMAN
NC score	0.038166 (rank : 504)	θ value	1.38821 (rank : 231)
Query Neighborhood Hits	375	Target Neighborhood Hits	451	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

SON_HUMAN
NC score	0.036713 (rank : 505)	θ value	0.00298849 (rank : 156)
Query Neighborhood Hits	375	Target Neighborhood Hits	1568	Shared Neighborhood Hits	108
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TARSH_HUMAN
NC score	0.035538 (rank : 506)	θ value	3.0926 (rank : 293)
Query Neighborhood Hits	375	Target Neighborhood Hits	768	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

OGFR_HUMAN
NC score	0.034985 (rank : 507)	θ value	0.00102713 (rank : 145)
Query Neighborhood Hits	375	Target Neighborhood Hits	1582	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

FMN2_HUMAN
NC score	0.034901 (rank : 508)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	375	Target Neighborhood Hits	484	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

IL4RA_HUMAN
NC score	0.034807 (rank : 509)	θ value	0.0736092 (rank : 170)
Query Neighborhood Hits	375	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

PCLO_MOUSE
NC score	0.034712 (rank : 510)	θ value	0.21417 (rank : 187)
Query Neighborhood Hits	375	Target Neighborhood Hits	2275	Shared Neighborhood Hits	136
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

BSN_MOUSE
NC score	0.034558 (rank : 511)	θ value	0.813845 (rank : 214)
Query Neighborhood Hits	375	Target Neighborhood Hits	2057	Shared Neighborhood Hits	130
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MLL2_HUMAN
NC score	0.034229 (rank : 512)	θ value	6.88961 (rank : 349)
Query Neighborhood Hits	375	Target Neighborhood Hits	1788	Shared Neighborhood Hits	139
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

GAB1_MOUSE
NC score	0.032668 (rank : 513)	θ value	0.0563607 (rank : 168)
Query Neighborhood Hits	375	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_HUMAN
NC score	0.032617 (rank : 514)	θ value	0.279714 (rank : 190)
Query Neighborhood Hits	375	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PRRT3_HUMAN
NC score	0.032435 (rank : 515)	θ value	0.0193708 (rank : 163)
Query Neighborhood Hits	375	Target Neighborhood Hits	998	Shared Neighborhood Hits	82
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RGS3_MOUSE
NC score	0.031949 (rank : 516)	θ value	0.0148317 (rank : 162)
Query Neighborhood Hits	375	Target Neighborhood Hits	1621	Shared Neighborhood Hits	106
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SYNJ1_HUMAN
NC score	0.031855 (rank : 517)	θ value	2.36792 (rank : 272)
Query Neighborhood Hits	375	Target Neighborhood Hits	498	Shared Neighborhood Hits	91
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CBP_MOUSE
NC score	0.031415 (rank : 518)	θ value	0.47712 (rank : 202)
Query Neighborhood Hits	375	Target Neighborhood Hits	1051	Shared Neighborhood Hits	98
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MDC1_HUMAN
NC score	0.031382 (rank : 519)	θ value	0.163984 (rank : 178)
Query Neighborhood Hits	375	Target Neighborhood Hits	1446	Shared Neighborhood Hits	90
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CD2_HUMAN
NC score	0.030347 (rank : 520)	θ value	0.21417 (rank : 183)
Query Neighborhood Hits	375	Target Neighborhood Hits	504	Shared Neighborhood Hits	42
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

PI5PA_HUMAN
NC score	0.030027 (rank : 521)	θ value	0.62314 (rank : 210)
Query Neighborhood Hits	375	Target Neighborhood Hits	749	Shared Neighborhood Hits	80
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ZN385_HUMAN
NC score	0.029814 (rank : 522)	θ value	3.0926 (rank : 295)
Query Neighborhood Hits	375	Target Neighborhood Hits	614	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CEL_HUMAN
NC score	0.029380 (rank : 523)	θ value	0.00175202 (rank : 149)
Query Neighborhood Hits	375	Target Neighborhood Hits	896	Shared Neighborhood Hits	81
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

BAT3_HUMAN
NC score	0.028737 (rank : 524)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	375	Target Neighborhood Hits	490	Shared Neighborhood Hits	63
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

MISS_MOUSE
NC score	0.027547 (rank : 525)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	375	Target Neighborhood Hits	444	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

IF4G1_MOUSE
NC score	0.027543 (rank : 526)	θ value	2.36792 (rank : 264)
Query Neighborhood Hits	375	Target Neighborhood Hits	534	Shared Neighborhood Hits	55
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K1543_HUMAN
NC score	0.027540 (rank : 527)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	375	Target Neighborhood Hits	435	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MAGE1_HUMAN
NC score	0.027105 (rank : 528)	θ value	0.279714 (rank : 191)
Query Neighborhood Hits	375	Target Neighborhood Hits	1389	Shared Neighborhood Hits	101
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CN004_MOUSE
NC score	0.026760 (rank : 529)	θ value	0.163984 (rank : 177)
Query Neighborhood Hits	375	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

CS007_MOUSE
NC score	0.025686 (rank : 530)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	375	Target Neighborhood Hits	464	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

GAK5_HUMAN
NC score	0.025345 (rank : 531)	θ value	0.62314 (rank : 207)
Query Neighborhood Hits	375	Target Neighborhood Hits	429	Shared Neighborhood Hits	43
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
NC score	0.024984 (rank : 532)	θ value	0.62314 (rank : 208)
Query Neighborhood Hits	375	Target Neighborhood Hits	392	Shared Neighborhood Hits	42
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

IL3B2_MOUSE
NC score	0.024869 (rank : 533)	θ value	3.0926 (rank : 281)
Query Neighborhood Hits	375	Target Neighborhood Hits	372	Shared Neighborhood Hits	42
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

BCL9_MOUSE
NC score	0.024571 (rank : 534)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	375	Target Neighborhood Hits	770	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

IL3RB_MOUSE
NC score	0.024203 (rank : 535)	θ value	3.0926 (rank : 282)
Query Neighborhood Hits	375	Target Neighborhood Hits	355	Shared Neighborhood Hits	37
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

GAK4_HUMAN
NC score	0.024169 (rank : 536)	θ value	1.38821 (rank : 236)
Query Neighborhood Hits	375	Target Neighborhood Hits	415	Shared Neighborhood Hits	44
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NCOA6_MOUSE
NC score	0.024097 (rank : 537)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	375	Target Neighborhood Hits	1076	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

RGS3_HUMAN
NC score	0.024093 (rank : 538)	θ value	0.21417 (rank : 188)
Query Neighborhood Hits	375	Target Neighborhood Hits	1375	Shared Neighborhood Hits	82
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MDC1_MOUSE
NC score	0.024082 (rank : 539)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	375	Target Neighborhood Hits	998	Shared Neighborhood Hits	80
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

FUT4_MOUSE
NC score	0.023872 (rank : 540)	θ value	2.36792 (rank : 261)
Query Neighborhood Hits	375	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q11127	Gene names	Fut4, Elft
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 4) (FUCT-IV) (Fuc-TIV).

PHC2_HUMAN
NC score	0.023666 (rank : 541)	θ value	0.279714 (rank : 193)
Query Neighborhood Hits	375	Target Neighborhood Hits	388	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

GAK11_HUMAN
NC score	0.023565 (rank : 542)	θ value	1.38821 (rank : 232)
Query Neighborhood Hits	375	Target Neighborhood Hits	409	Shared Neighborhood Hits	43
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NCOA6_HUMAN
NC score	0.023272 (rank : 543)	θ value	2.36792 (rank : 268)
Query Neighborhood Hits	375	Target Neighborhood Hits	1202	Shared Neighborhood Hits	98
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

GAK12_HUMAN
NC score	0.023250 (rank : 544)	θ value	1.38821 (rank : 233)
Query Neighborhood Hits	375	Target Neighborhood Hits	374	Shared Neighborhood Hits	43
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.023168 (rank : 545)	θ value	1.38821 (rank : 235)
Query Neighborhood Hits	375	Target Neighborhood Hits	406	Shared Neighborhood Hits	42
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SPR1A_MOUSE
NC score	0.023154 (rank : 546)	θ value	0.365318 (rank : 201)
Query Neighborhood Hits	375	Target Neighborhood Hits	343	Shared Neighborhood Hits	36
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

MLL3_HUMAN
NC score	0.022792 (rank : 547)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	375	Target Neighborhood Hits	1644	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CJ108_HUMAN
NC score	0.022485 (rank : 548)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	375	Target Neighborhood Hits	165	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

GAK1_HUMAN
NC score	0.022309 (rank : 549)	θ value	1.38821 (rank : 234)
Query Neighborhood Hits	375	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PPRB_HUMAN
NC score	0.021559 (rank : 550)	θ value	5.27518 (rank : 327)
Query Neighborhood Hits	375	Target Neighborhood Hits	311	Shared Neighborhood Hits	33
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SPR1B_MOUSE
NC score	0.021399 (rank : 551)	θ value	0.62314 (rank : 213)
Query Neighborhood Hits	375	Target Neighborhood Hits	395	Shared Neighborhood Hits	41
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

MKL2_MOUSE
NC score	0.021311 (rank : 552)	θ value	3.0926 (rank : 287)
Query Neighborhood Hits	375	Target Neighborhood Hits	269	Shared Neighborhood Hits	29
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

SC24A_MOUSE
NC score	0.021049 (rank : 553)	θ value	3.0926 (rank : 291)
Query Neighborhood Hits	375	Target Neighborhood Hits	394	Shared Neighborhood Hits	56
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

BCL7C_MOUSE
NC score	0.020473 (rank : 554)	θ value	1.81305 (rank : 242)
Query Neighborhood Hits	375	Target Neighborhood Hits	170	Shared Neighborhood Hits	25
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

BCL9_HUMAN
NC score	0.020458 (rank : 555)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	375	Target Neighborhood Hits	1008	Shared Neighborhood Hits	90
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

DKK3_MOUSE
NC score	0.020205 (rank : 556)	θ value	1.81305 (rank : 243)
Query Neighborhood Hits	375	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

MLL3_MOUSE
NC score	0.020196 (rank : 557)	θ value	0.365318 (rank : 198)
Query Neighborhood Hits	375	Target Neighborhood Hits	1399	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PRP6_MOUSE
NC score	0.020171 (rank : 558)	θ value	1.81305 (rank : 252)
Query Neighborhood Hits	375	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YR7, Q8CIK9, Q8R3M8, Q99JN1, Q9CSZ0	Gene names	Prpf6
Domain Architecture
Description	Pre-mRNA-processing factor 6 homolog (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein).

PRP6_HUMAN
NC score	0.020135 (rank : 559)	θ value	1.81305 (rank : 251)
Query Neighborhood Hits	375	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	O94906, O95109, Q5VXS5, Q9H3Z1, Q9H4T9, Q9H4U8, Q9NTE6	Gene names	PRPF6, C20orf14
Domain Architecture
Description	Pre-mRNA-processing factor 6 homolog (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein).

ARMX2_MOUSE
NC score	0.019873 (rank : 560)	θ value	1.06291 (rank : 220)
Query Neighborhood Hits	375	Target Neighborhood Hits	349	Shared Neighborhood Hits	38
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

SAPS1_HUMAN
NC score	0.019799 (rank : 561)	θ value	0.813845 (rank : 218)
Query Neighborhood Hits	375	Target Neighborhood Hits	704	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

PSL1_HUMAN
NC score	0.019789 (rank : 562)	θ value	0.62314 (rank : 211)
Query Neighborhood Hits	375	Target Neighborhood Hits	650	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

K1802_HUMAN
NC score	0.019446 (rank : 563)	θ value	2.36792 (rank : 265)
Query Neighborhood Hits	375	Target Neighborhood Hits	1378	Shared Neighborhood Hits	102
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

INP5E_HUMAN
NC score	0.019141 (rank : 564)	θ value	1.81305 (rank : 246)
Query Neighborhood Hits	375	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

TPO_MOUSE
NC score	0.018669 (rank : 565)	θ value	8.99809 (rank : 374)
Query Neighborhood Hits	375	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

EFS_HUMAN
NC score	0.018367 (rank : 566)	θ value	3.0926 (rank : 277)
Query Neighborhood Hits	375	Target Neighborhood Hits	348	Shared Neighborhood Hits	49
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

CPSF7_MOUSE
NC score	0.018359 (rank : 567)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	375	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

CPSF7_HUMAN
NC score	0.018256 (rank : 568)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	375	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

MINT_MOUSE
NC score	0.017964 (rank : 569)	θ value	3.0926 (rank : 286)
Query Neighborhood Hits	375	Target Neighborhood Hits	1514	Shared Neighborhood Hits	92
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GNAS1_MOUSE
NC score	0.017872 (rank : 570)	θ value	4.03905 (rank : 306)
Query Neighborhood Hits	375	Target Neighborhood Hits	651	Shared Neighborhood Hits	63
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

RUSC2_MOUSE
NC score	0.017633 (rank : 571)	θ value	2.36792 (rank : 271)
Query Neighborhood Hits	375	Target Neighborhood Hits	305	Shared Neighborhood Hits	32
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

UNG_HUMAN
NC score	0.017624 (rank : 572)	θ value	6.88961 (rank : 354)
Query Neighborhood Hits	375	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P13051, O00637, O00719, Q93028	Gene names	UNG, DGU, UNG15
Domain Architecture
Description	Uracil-DNA glycosylase (EC 3.2.2.-) (UDG).

GAK7_HUMAN
NC score	0.017517 (rank : 573)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	375	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

TXND2_HUMAN
NC score	0.017272 (rank : 574)	θ value	4.03905 (rank : 314)
Query Neighborhood Hits	375	Target Neighborhood Hits	793	Shared Neighborhood Hits	47
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

PRAX_MOUSE
NC score	0.017001 (rank : 575)	θ value	8.99809 (rank : 370)
Query Neighborhood Hits	375	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SSBP4_HUMAN
NC score	0.016896 (rank : 576)	θ value	0.279714 (rank : 194)
Query Neighborhood Hits	375	Target Neighborhood Hits	753	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

LAD1_MOUSE
NC score	0.016133 (rank : 577)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	375	Target Neighborhood Hits	391	Shared Neighborhood Hits	33
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

PSMF1_MOUSE
NC score	0.015621 (rank : 578)	θ value	3.0926 (rank : 290)
Query Neighborhood Hits	375	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

CSKI1_HUMAN
NC score	0.015374 (rank : 579)	θ value	2.36792 (rank : 258)
Query Neighborhood Hits	375	Target Neighborhood Hits	997	Shared Neighborhood Hits	97
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

AL2S4_MOUSE
NC score	0.014597 (rank : 580)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	375	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

E2F5_HUMAN
NC score	0.013656 (rank : 581)	θ value	1.38821 (rank : 230)
Query Neighborhood Hits	375	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

SEPT9_HUMAN
NC score	0.013604 (rank : 582)	θ value	0.813845 (rank : 219)
Query Neighborhood Hits	375	Target Neighborhood Hits	706	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CSKI1_MOUSE
NC score	0.013558 (rank : 583)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	375	Target Neighborhood Hits	1031	Shared Neighborhood Hits	94
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CT012_MOUSE
NC score	0.013530 (rank : 584)	θ value	2.36792 (rank : 259)
Query Neighborhood Hits	375	Target Neighborhood Hits	229	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

CBL_MOUSE
NC score	0.013342 (rank : 585)	θ value	0.279714 (rank : 189)
Query Neighborhood Hits	375	Target Neighborhood Hits	426	Shared Neighborhood Hits	33
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

NADAP_HUMAN
NC score	0.013238 (rank : 586)	θ value	1.81305 (rank : 249)
Query Neighborhood Hits	375	Target Neighborhood Hits	208	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

TMEPA_MOUSE
NC score	0.013191 (rank : 587)	θ value	2.36792 (rank : 273)
Query Neighborhood Hits	375	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

OBSCN_HUMAN
NC score	0.012989 (rank : 588)	θ value	3.0926 (rank : 288)
Query Neighborhood Hits	375	Target Neighborhood Hits	1931	Shared Neighborhood Hits	90
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

LSD1_HUMAN
NC score	0.012945 (rank : 589)	θ value	1.81305 (rank : 247)
Query Neighborhood Hits	375	Target Neighborhood Hits	455	Shared Neighborhood Hits	26
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

FOXN1_HUMAN
NC score	0.012674 (rank : 590)	θ value	0.813845 (rank : 215)
Query Neighborhood Hits	375	Target Neighborhood Hits	377	Shared Neighborhood Hits	30
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

SPEG_MOUSE
NC score	0.012628 (rank : 591)	θ value	5.27518 (rank : 334)
Query Neighborhood Hits	375	Target Neighborhood Hits	1959	Shared Neighborhood Hits	122
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

HPS4_MOUSE
NC score	0.012292 (rank : 592)	θ value	3.0926 (rank : 280)
Query Neighborhood Hits	375	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

SYNPO_HUMAN
NC score	0.012083 (rank : 593)	θ value	5.27518 (rank : 335)
Query Neighborhood Hits	375	Target Neighborhood Hits	281	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TAB3_MOUSE
NC score	0.011340 (rank : 594)	θ value	8.99809 (rank : 373)
Query Neighborhood Hits	375	Target Neighborhood Hits	273	Shared Neighborhood Hits	36
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

MYO15_HUMAN
NC score	0.011254 (rank : 595)	θ value	0.163984 (rank : 179)
Query Neighborhood Hits	375	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

K1802_MOUSE
NC score	0.010876 (rank : 596)	θ value	4.03905 (rank : 309)
Query Neighborhood Hits	375	Target Neighborhood Hits	1596	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ECM1_HUMAN
NC score	0.010786 (rank : 597)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	375	Target Neighborhood Hits	182	Shared Neighborhood Hits	28
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

FOXN1_MOUSE
NC score	0.010700 (rank : 598)	θ value	0.47712 (rank : 203)
Query Neighborhood Hits	375	Target Neighborhood Hits	300	Shared Neighborhood Hits	22
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

SPEG_HUMAN
NC score	0.010495 (rank : 599)	θ value	6.88961 (rank : 352)
Query Neighborhood Hits	375	Target Neighborhood Hits	1762	Shared Neighborhood Hits	120
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UB7I1_MOUSE
NC score	0.010362 (rank : 600)	θ value	2.36792 (rank : 274)
Query Neighborhood Hits	375	Target Neighborhood Hits	206	Shared Neighborhood Hits	18
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

MAP1A_HUMAN
NC score	0.010350 (rank : 601)	θ value	3.0926 (rank : 285)
Query Neighborhood Hits	375	Target Neighborhood Hits	1626	Shared Neighborhood Hits	85
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

HGS_HUMAN
NC score	0.010148 (rank : 602)	θ value	1.06291 (rank : 222)
Query Neighborhood Hits	375	Target Neighborhood Hits	517	Shared Neighborhood Hits	31
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

OBF1_HUMAN
NC score	0.010023 (rank : 603)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	375	Target Neighborhood Hits	203	Shared Neighborhood Hits	24
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

GCH1_HUMAN
NC score	0.009247 (rank : 604)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	375	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

ZIM10_MOUSE
NC score	0.009094 (rank : 605)	θ value	6.88961 (rank : 356)
Query Neighborhood Hits	375	Target Neighborhood Hits	430	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

TMM24_MOUSE
NC score	0.008993 (rank : 606)	θ value	5.27518 (rank : 336)
Query Neighborhood Hits	375	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

EDD1_HUMAN
NC score	0.008950 (rank : 607)	θ value	1.81305 (rank : 244)
Query Neighborhood Hits	375	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

TOP1_MOUSE
NC score	0.008704 (rank : 608)	θ value	3.0926 (rank : 294)
Query Neighborhood Hits	375	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

RBBP6_HUMAN
NC score	0.008661 (rank : 609)	θ value	1.06291 (rank : 225)
Query Neighborhood Hits	375	Target Neighborhood Hits	1135	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TTLL5_MOUSE
NC score	0.008606 (rank : 610)	θ value	1.81305 (rank : 255)
Query Neighborhood Hits	375	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

ZIM10_HUMAN
NC score	0.008540 (rank : 611)	θ value	6.88961 (rank : 355)
Query Neighborhood Hits	375	Target Neighborhood Hits	577	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

RP3A_MOUSE
NC score	0.008398 (rank : 612)	θ value	1.81305 (rank : 253)
Query Neighborhood Hits	375	Target Neighborhood Hits	510	Shared Neighborhood Hits	48
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

EDD1_MOUSE
NC score	0.008310 (rank : 613)	θ value	2.36792 (rank : 260)
Query Neighborhood Hits	375	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

TIE1_MOUSE
NC score	0.008232 (rank : 614)	θ value	1.38821 (rank : 241)
Query Neighborhood Hits	375	Target Neighborhood Hits	1266	Shared Neighborhood Hits	50
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

FOXH1_HUMAN
NC score	0.008074 (rank : 615)	θ value	1.06291 (rank : 221)
Query Neighborhood Hits	375	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

RPGF1_HUMAN
NC score	0.007983 (rank : 616)	θ value	1.38821 (rank : 238)
Query Neighborhood Hits	375	Target Neighborhood Hits	262	Shared Neighborhood Hits	19
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

NUMBL_HUMAN
NC score	0.007948 (rank : 617)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	375	Target Neighborhood Hits	394	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

TIE1_HUMAN
NC score	0.007774 (rank : 618)	θ value	4.03905 (rank : 313)
Query Neighborhood Hits	375	Target Neighborhood Hits	1241	Shared Neighborhood Hits	48
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

IF4B_MOUSE
NC score	0.007746 (rank : 619)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	375	Target Neighborhood Hits	368	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

CN092_MOUSE
NC score	0.007729 (rank : 620)	θ value	8.99809 (rank : 358)
Query Neighborhood Hits	375	Target Neighborhood Hits	206	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

ANK2_HUMAN
NC score	0.007712 (rank : 621)	θ value	0.365318 (rank : 195)
Query Neighborhood Hits	375	Target Neighborhood Hits	1615	Shared Neighborhood Hits	80
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ERRFI_HUMAN
NC score	0.007703 (rank : 622)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	375	Target Neighborhood Hits	72	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

BRD3_MOUSE
NC score	0.007634 (rank : 623)	θ value	2.36792 (rank : 257)
Query Neighborhood Hits	375	Target Neighborhood Hits	402	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

CAC1G_HUMAN
NC score	0.006753 (rank : 624)	θ value	1.38821 (rank : 227)
Query Neighborhood Hits	375	Target Neighborhood Hits	587	Shared Neighborhood Hits	48
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

NFH_MOUSE
NC score	0.006342 (rank : 625)	θ value	0.813845 (rank : 216)
Query Neighborhood Hits	375	Target Neighborhood Hits	2247	Shared Neighborhood Hits	95
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

JADE2_MOUSE
NC score	0.006234 (rank : 626)	θ value	4.03905 (rank : 308)
Query Neighborhood Hits	375	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

HAPIP_HUMAN
NC score	0.005894 (rank : 627)	θ value	1.38821 (rank : 237)
Query Neighborhood Hits	375	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

PKHA6_HUMAN
NC score	0.005802 (rank : 628)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	375	Target Neighborhood Hits	556	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MAGD1_HUMAN
NC score	0.005078 (rank : 629)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	375	Target Neighborhood Hits	130	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5V3, Q5VSH6, Q8IZ84, Q8WY92, Q9H352, Q9HBT4, Q9UF36	Gene names	MAGED1, NRAGE
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (MAGE tumor antigen CCF).

RC3H1_HUMAN
NC score	0.004798 (rank : 630)	θ value	5.27518 (rank : 329)
Query Neighborhood Hits	375	Target Neighborhood Hits	433	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

CO6A3_HUMAN
NC score	0.004490 (rank : 631)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	375	Target Neighborhood Hits	317	Shared Neighborhood Hits	32
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

ETV3_HUMAN
NC score	0.004267 (rank : 632)	θ value	4.03905 (rank : 303)
Query Neighborhood Hits	375	Target Neighborhood Hits	312	Shared Neighborhood Hits	32
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

HCLS1_HUMAN
NC score	0.004183 (rank : 633)	θ value	3.0926 (rank : 279)
Query Neighborhood Hits	375	Target Neighborhood Hits	358	Shared Neighborhood Hits	25
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

PYR1_HUMAN
NC score	0.004163 (rank : 634)	θ value	5.27518 (rank : 328)
Query Neighborhood Hits	375	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

TXLNB_HUMAN
NC score	0.004146 (rank : 635)	θ value	0.47712 (rank : 206)
Query Neighborhood Hits	375	Target Neighborhood Hits	912	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

TCF7_MOUSE
NC score	0.004051 (rank : 636)	θ value	4.03905 (rank : 312)
Query Neighborhood Hits	375	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

SSH1_HUMAN
NC score	0.004033 (rank : 637)	θ value	3.0926 (rank : 292)
Query Neighborhood Hits	375	Target Neighborhood Hits	164	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

K1849_MOUSE
NC score	0.003741 (rank : 638)	θ value	2.36792 (rank : 266)
Query Neighborhood Hits	375	Target Neighborhood Hits	335	Shared Neighborhood Hits	10
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

CLMN_MOUSE
NC score	0.002409 (rank : 639)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	375	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

RECQ4_MOUSE
NC score	0.002065 (rank : 640)	θ value	5.27518 (rank : 330)
Query Neighborhood Hits	375	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

SC6A3_HUMAN
NC score	0.001900 (rank : 641)	θ value	5.27518 (rank : 331)
Query Neighborhood Hits	375	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q01959, Q14996	Gene names	SLC6A3, DAT1
Domain Architecture
Description	Sodium-dependent dopamine transporter (DA transporter) (DAT).

SMAL1_MOUSE
NC score	0.001870 (rank : 642)	θ value	5.27518 (rank : 333)
Query Neighborhood Hits	375	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SC6A3_MOUSE
NC score	0.001870 (rank : 643)	θ value	5.27518 (rank : 332)
Query Neighborhood Hits	375	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q61327, Q60719, Q9R1I2	Gene names	Slc6a3, Dat, Dat1
Domain Architecture
Description	Sodium-dependent dopamine transporter (DA transporter) (DAT).

CEP35_HUMAN
NC score	0.001539 (rank : 644)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	375	Target Neighborhood Hits	811	Shared Neighborhood Hits	24
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

SFR12_MOUSE
NC score	0.000344 (rank : 645)	θ value	8.99809 (rank : 371)
Query Neighborhood Hits	375	Target Neighborhood Hits	486	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

LIMD1_MOUSE
NC score	0.000166 (rank : 646)	θ value	6.88961 (rank : 348)
Query Neighborhood Hits	375	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

ZN687_HUMAN
NC score	0.000087 (rank : 647)	θ value	0.0961366 (rank : 175)
Query Neighborhood Hits	375	Target Neighborhood Hits	1244	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

DZIP1_MOUSE
NC score	-0.000458 (rank : 648)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	375	Target Neighborhood Hits	530	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

MAST4_HUMAN
NC score	-0.000533 (rank : 649)	θ value	0.125558 (rank : 176)
Query Neighborhood Hits	375	Target Neighborhood Hits	1804	Shared Neighborhood Hits	83
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

RX_MOUSE
NC score	-0.001119 (rank : 650)	θ value	1.38821 (rank : 240)
Query Neighborhood Hits	375	Target Neighborhood Hits	429	Shared Neighborhood Hits	19
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

OR4B1_HUMAN
NC score	-0.001254 (rank : 651)	θ value	3.0926 (rank : 289)
Query Neighborhood Hits	375	Target Neighborhood Hits	652	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NGF8, Q6IF75, Q96R64	Gene names	OR4B1
Domain Architecture
Description	Olfactory receptor 4B1 (OST208) (Olfactory receptor OR11-106).

IGF1R_HUMAN
NC score	-0.001882 (rank : 652)	θ value	4.03905 (rank : 307)
Query Neighborhood Hits	375	Target Neighborhood Hits	977	Shared Neighborhood Hits	40
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

O10J6_HUMAN
NC score	-0.002739 (rank : 653)	θ value	0.813845 (rank : 217)
Query Neighborhood Hits	375	Target Neighborhood Hits	732	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NGY7, Q96R55	Gene names	OR10J6
Domain Architecture
Description	Olfactory receptor 10J6.

AATK_HUMAN
NC score	-0.003459 (rank : 654)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	375	Target Neighborhood Hits	1243	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

DUET_HUMAN
NC score	-0.003706 (rank : 655)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	375	Target Neighborhood Hits	1220	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

BKRB2_HUMAN
NC score	-0.003918 (rank : 656)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	375	Target Neighborhood Hits	533	Shared Neighborhood Hits	9
SwissProt Accessions	P30411	Gene names	BDKRB2, BKR2
Domain Architecture
Description	B2 bradykinin receptor (BK-2 receptor) (B2R).

ERBB2_HUMAN
NC score	-0.004184 (rank : 657)	θ value	1.81305 (rank : 245)
Query Neighborhood Hits	375	Target Neighborhood Hits	1073	Shared Neighborhood Hits	39
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

OR6X1_HUMAN
NC score	-0.004904 (rank : 658)	θ value	0.365318 (rank : 199)
Query Neighborhood Hits	375	Target Neighborhood Hits	771	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NH79, Q6IFA0	Gene names	OR6X1
Domain Architecture
Description	Olfactory receptor 6X1 (Olfactory receptor OR11-270).

OR4D1_HUMAN
NC score	-0.005182 (rank : 659)	θ value	1.06291 (rank : 223)
Query Neighborhood Hits	375	Target Neighborhood Hits	804	Shared Neighborhood Hits	11
SwissProt Accessions	Q15615, Q8NGB1, Q96R76	Gene names	OR4D1, OR4D3
Domain Architecture
Description	Olfactory receptor 4D1 (Olfactory receptor TPCR16).

O10A4_HUMAN
NC score	-0.005419 (rank : 660)	θ value	8.99809 (rank : 369)
Query Neighborhood Hits	375	Target Neighborhood Hits	686	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H209, Q96R20	Gene names	OR10A4
Domain Architecture
Description	Olfactory receptor 10A4 (HP2) (Olfactory receptor-like protein JCG5).

ZN516_MOUSE
NC score	-0.006724 (rank : 661)	θ value	3.0926 (rank : 296)
Query Neighborhood Hits	375	Target Neighborhood Hits	1197	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

LATS2_HUMAN
NC score	-0.006943 (rank : 662)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	375	Target Neighborhood Hits	884	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

OR6K2_HUMAN
NC score	-0.007306 (rank : 663)	θ value	6.88961 (rank : 350)
Query Neighborhood Hits	375	Target Neighborhood Hits	711	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NGY2	Gene names	OR6K2
Domain Architecture
Description	Olfactory receptor 6K2.

ACM3_HUMAN
NC score	-0.008204 (rank : 664)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	375	Target Neighborhood Hits	931	Shared Neighborhood Hits	10
SwissProt Accessions	P20309, Q4QRI3, Q5VXY2, Q9HB60	Gene names	CHRM3
Domain Architecture
Description	Muscarinic acetylcholine receptor M3.

PKN3_MOUSE
NC score	-0.008329 (rank : 665)	θ value	4.03905 (rank : 311)
Query Neighborhood Hits	375	Target Neighborhood Hits	1009	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PAK4_HUMAN
NC score	-0.008573 (rank : 666)	θ value	6.88961 (rank : 351)
Query Neighborhood Hits	375	Target Neighborhood Hits	924	Shared Neighborhood Hits	37
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

ZN282_HUMAN
NC score	-0.009812 (rank : 667)	θ value	8.99809 (rank : 375)
Query Neighborhood Hits	375	Target Neighborhood Hits	796	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).