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Network neighborhood for query Sequence : RSPO1_HUMAN

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RSPO1_HUMAN
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RSPO1_HUMAN
θ value	1.42253e-146 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	101	Target Neighborhood Hits	101	Shared Neighborhood Hits	101
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
θ value	6.41512e-131 (rank : 2)	NC score	0.988062 (rank : 2)
Query Neighborhood Hits	101	Target Neighborhood Hits	85	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO3_MOUSE
θ value	3.71096e-62 (rank : 3)	NC score	0.953322 (rank : 3)
Query Neighborhood Hits	101	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO3_HUMAN
θ value	6.32992e-62 (rank : 4)	NC score	0.948482 (rank : 4)
Query Neighborhood Hits	101	Target Neighborhood Hits	128	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO2_HUMAN
θ value	2.25659e-51 (rank : 5)	NC score	0.934779 (rank : 5)
Query Neighborhood Hits	101	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	3.84914e-51 (rank : 6)	NC score	0.933958 (rank : 6)
Query Neighborhood Hits	101	Target Neighborhood Hits	88	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO4_HUMAN
θ value	1.2411e-41 (rank : 7)	NC score	0.909750 (rank : 7)
Query Neighborhood Hits	101	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	5.39604e-37 (rank : 8)	NC score	0.907532 (rank : 8)
Query Neighborhood Hits	101	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

PCSK5_MOUSE
θ value	1.33837e-11 (rank : 9)	NC score	0.303110 (rank : 15)
Query Neighborhood Hits	101	Target Neighborhood Hits	613	Shared Neighborhood Hits	76
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK5_HUMAN
θ value	8.11959e-09 (rank : 10)	NC score	0.306858 (rank : 11)
Query Neighborhood Hits	101	Target Neighborhood Hits	291	Shared Neighborhood Hits	64
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
θ value	1.38499e-08 (rank : 11)	NC score	0.312790 (rank : 10)
Query Neighborhood Hits	101	Target Neighborhood Hits	298	Shared Neighborhood Hits	56
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

FRAS1_HUMAN
θ value	1.09739e-05 (rank : 12)	NC score	0.254600 (rank : 17)
Query Neighborhood Hits	101	Target Neighborhood Hits	759	Shared Neighborhood Hits	81
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	1.09739e-05 (rank : 13)	NC score	0.256421 (rank : 16)
Query Neighborhood Hits	101	Target Neighborhood Hits	747	Shared Neighborhood Hits	81
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SPON1_HUMAN
θ value	4.1701e-05 (rank : 14)	NC score	0.304796 (rank : 13)
Query Neighborhood Hits	101	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	5.44631e-05 (rank : 15)	NC score	0.305342 (rank : 12)
Query Neighborhood Hits	101	Target Neighborhood Hits	123	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SSPO_MOUSE
θ value	0.000602161 (rank : 16)	NC score	0.185380 (rank : 20)
Query Neighborhood Hits	101	Target Neighborhood Hits	800	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TNR6B_HUMAN
θ value	0.000786445 (rank : 17)	NC score	0.178360 (rank : 21)
Query Neighborhood Hits	101	Target Neighborhood Hits	103	Shared Neighborhood Hits	32
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

SPON2_HUMAN
θ value	0.00175202 (rank : 18)	NC score	0.313188 (rank : 9)
Query Neighborhood Hits	101	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON2_MOUSE
θ value	0.00665767 (rank : 19)	NC score	0.303294 (rank : 14)
Query Neighborhood Hits	101	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

BAI3_HUMAN
θ value	0.0113563 (rank : 20)	NC score	0.158142 (rank : 26)
Query Neighborhood Hits	101	Target Neighborhood Hits	246	Shared Neighborhood Hits	52
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	0.0148317 (rank : 21)	NC score	0.157912 (rank : 27)
Query Neighborhood Hits	101	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

INSR_MOUSE
θ value	0.0193708 (rank : 22)	NC score	0.064987 (rank : 150)
Query Neighborhood Hits	101	Target Neighborhood Hits	968	Shared Neighborhood Hits	35
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

BAI2_MOUSE
θ value	0.0252991 (rank : 23)	NC score	0.170322 (rank : 23)
Query Neighborhood Hits	101	Target Neighborhood Hits	323	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
θ value	0.0431538 (rank : 24)	NC score	0.170762 (rank : 22)
Query Neighborhood Hits	101	Target Neighborhood Hits	332	Shared Neighborhood Hits	52
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CILP1_HUMAN
θ value	0.0431538 (rank : 25)	NC score	0.146941 (rank : 30)
Query Neighborhood Hits	101	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

PROP_MOUSE
θ value	0.0431538 (rank : 26)	NC score	0.216539 (rank : 18)
Query Neighborhood Hits	101	Target Neighborhood Hits	165	Shared Neighborhood Hits	51
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

IGF1R_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.067802 (rank : 143)
Query Neighborhood Hits	101	Target Neighborhood Hits	977	Shared Neighborhood Hits	42
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_HUMAN
θ value	0.0563607 (rank : 28)	NC score	0.070113 (rank : 131)
Query Neighborhood Hits	101	Target Neighborhood Hits	950	Shared Neighborhood Hits	38
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

BAI1_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.157066 (rank : 28)
Query Neighborhood Hits	101	Target Neighborhood Hits	375	Shared Neighborhood Hits	52
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.151697 (rank : 29)
Query Neighborhood Hits	101	Target Neighborhood Hits	340	Shared Neighborhood Hits	47
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CILP1_MOUSE
θ value	0.0736092 (rank : 31)	NC score	0.128306 (rank : 36)
Query Neighborhood Hits	101	Target Neighborhood Hits	282	Shared Neighborhood Hits	41
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP2_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.142671 (rank : 31)
Query Neighborhood Hits	101	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

PROP_HUMAN
θ value	0.0736092 (rank : 33)	NC score	0.201906 (rank : 19)
Query Neighborhood Hits	101	Target Neighborhood Hits	126	Shared Neighborhood Hits	53
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

TR11B_HUMAN
θ value	0.0736092 (rank : 34)	NC score	0.107086 (rank : 45)
Query Neighborhood Hits	101	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

INSR_HUMAN
θ value	0.0961366 (rank : 35)	NC score	0.062707 (rank : 158)
Query Neighborhood Hits	101	Target Neighborhood Hits	963	Shared Neighborhood Hits	36
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TR11B_MOUSE
θ value	0.0961366 (rank : 36)	NC score	0.084723 (rank : 84)
Query Neighborhood Hits	101	Target Neighborhood Hits	95	Shared Neighborhood Hits	18
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

CREL1_HUMAN
θ value	0.125558 (rank : 37)	NC score	0.123911 (rank : 38)
Query Neighborhood Hits	101	Target Neighborhood Hits	441	Shared Neighborhood Hits	46
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

SCUB3_MOUSE
θ value	0.125558 (rank : 38)	NC score	0.082469 (rank : 90)
Query Neighborhood Hits	101	Target Neighborhood Hits	442	Shared Neighborhood Hits	51
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ATS16_MOUSE
θ value	0.163984 (rank : 39)	NC score	0.112616 (rank : 42)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	47
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

CREL1_MOUSE
θ value	0.163984 (rank : 40)	NC score	0.127554 (rank : 37)
Query Neighborhood Hits	101	Target Neighborhood Hits	524	Shared Neighborhood Hits	49
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

INSRR_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.067673 (rank : 144)
Query Neighborhood Hits	101	Target Neighborhood Hits	961	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LTBP4_MOUSE
θ value	0.163984 (rank : 42)	NC score	0.082400 (rank : 91)
Query Neighborhood Hits	101	Target Neighborhood Hits	607	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

ATS20_MOUSE
θ value	0.21417 (rank : 43)	NC score	0.109578 (rank : 43)
Query Neighborhood Hits	101	Target Neighborhood Hits	225	Shared Neighborhood Hits	53
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

IGF1R_MOUSE
θ value	0.21417 (rank : 44)	NC score	0.068583 (rank : 138)
Query Neighborhood Hits	101	Target Neighborhood Hits	973	Shared Neighborhood Hits	42
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

DLL3_MOUSE
θ value	0.279714 (rank : 45)	NC score	0.050253 (rank : 231)
Query Neighborhood Hits	101	Target Neighborhood Hits	399	Shared Neighborhood Hits	40
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

LAMB2_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.062075 (rank : 163)
Query Neighborhood Hits	101	Target Neighborhood Hits	692	Shared Neighborhood Hits	48
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

TNR14_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.103214 (rank : 54)
Query Neighborhood Hits	101	Target Neighborhood Hits	149	Shared Neighborhood Hits	36
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ATL5_HUMAN
θ value	0.365318 (rank : 48)	NC score	0.095844 (rank : 61)
Query Neighborhood Hits	101	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

BMPER_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.112739 (rank : 41)
Query Neighborhood Hits	101	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

TSP2_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.133319 (rank : 35)
Query Neighborhood Hits	101	Target Neighborhood Hits	352	Shared Neighborhood Hits	69
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATS1_MOUSE
θ value	0.47712 (rank : 51)	NC score	0.081425 (rank : 97)
Query Neighborhood Hits	101	Target Neighborhood Hits	158	Shared Neighborhood Hits	41
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

LTBP2_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.076431 (rank : 111)
Query Neighborhood Hits	101	Target Neighborhood Hits	617	Shared Neighborhood Hits	51
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SCUB3_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.074740 (rank : 117)
Query Neighborhood Hits	101	Target Neighborhood Hits	428	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ATS16_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.104785 (rank : 49)
Query Neighborhood Hits	101	Target Neighborhood Hits	208	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

FURIN_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.168277 (rank : 24)
Query Neighborhood Hits	101	Target Neighborhood Hits	52	Shared Neighborhood Hits	21
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

TNR22_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.082379 (rank : 92)
Query Neighborhood Hits	101	Target Neighborhood Hits	97	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

ATS17_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.104969 (rank : 48)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

BMPER_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.096930 (rank : 59)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CO8B_MOUSE
θ value	1.06291 (rank : 59)	NC score	0.089972 (rank : 72)
Query Neighborhood Hits	101	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

HMCN1_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.102077 (rank : 56)
Query Neighborhood Hits	101	Target Neighborhood Hits	983	Shared Neighborhood Hits	82
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LAMA2_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.057120 (rank : 189)
Query Neighborhood Hits	101	Target Neighborhood Hits	1198	Shared Neighborhood Hits	54
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ATS12_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.090219 (rank : 71)
Query Neighborhood Hits	101	Target Neighborhood Hits	220	Shared Neighborhood Hits	43
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

LAMA5_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.068274 (rank : 140)
Query Neighborhood Hits	101	Target Neighborhood Hits	976	Shared Neighborhood Hits	62
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF8_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.078831 (rank : 102)
Query Neighborhood Hits	101	Target Neighborhood Hits	528	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NOTC3_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.053913 (rank : 205)
Query Neighborhood Hits	101	Target Neighborhood Hits	1062	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TNR26_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.079889 (rank : 99)
Query Neighborhood Hits	101	Target Neighborhood Hits	106	Shared Neighborhood Hits	23
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR5_MOUSE
θ value	1.81305 (rank : 67)	NC score	0.116388 (rank : 40)
Query Neighborhood Hits	101	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

EGFR_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.030007 (rank : 234)
Query Neighborhood Hits	101	Target Neighborhood Hits	927	Shared Neighborhood Hits	34
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

FURIN_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.163338 (rank : 25)
Query Neighborhood Hits	101	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

LAMA1_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.059871 (rank : 172)
Query Neighborhood Hits	101	Target Neighborhood Hits	838	Shared Neighborhood Hits	58
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

ATS20_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.102889 (rank : 55)
Query Neighborhood Hits	101	Target Neighborhood Hits	192	Shared Neighborhood Hits	53
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CO8B_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.085412 (rank : 83)
Query Neighborhood Hits	101	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

FBN2_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.064712 (rank : 152)
Query Neighborhood Hits	101	Target Neighborhood Hits	549	Shared Neighborhood Hits	52
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LHX4_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.017274 (rank : 238)
Query Neighborhood Hits	101	Target Neighborhood Hits	455	Shared Neighborhood Hits	7
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LHX4_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.017280 (rank : 237)
Query Neighborhood Hits	101	Target Neighborhood Hits	457	Shared Neighborhood Hits	7
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

ODFP_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.029240 (rank : 235)
Query Neighborhood Hits	101	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

SREC2_MOUSE
θ value	3.0926 (rank : 77)	NC score	0.094300 (rank : 64)
Query Neighborhood Hits	101	Target Neighborhood Hits	605	Shared Neighborhood Hits	55
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TNR1A_MOUSE
θ value	3.0926 (rank : 78)	NC score	0.067604 (rank : 145)
Query Neighborhood Hits	101	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TSP2_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.133903 (rank : 34)
Query Neighborhood Hits	101	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATS12_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.087981 (rank : 76)
Query Neighborhood Hits	101	Target Neighborhood Hits	251	Shared Neighborhood Hits	43
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS1_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.076522 (rank : 110)
Query Neighborhood Hits	101	Target Neighborhood Hits	159	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS6_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.078658 (rank : 103)
Query Neighborhood Hits	101	Target Neighborhood Hits	141	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

KRA53_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.084715 (rank : 85)
Query Neighborhood Hits	101	Target Neighborhood Hits	331	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

SEM5B_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.088131 (rank : 75)
Query Neighborhood Hits	101	Target Neighborhood Hits	178	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

TSP1_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.138970 (rank : 32)
Query Neighborhood Hits	101	Target Neighborhood Hits	396	Shared Neighborhood Hits	75
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

UNC5B_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.091900 (rank : 68)
Query Neighborhood Hits	101	Target Neighborhood Hits	225	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.092044 (rank : 67)
Query Neighborhood Hits	101	Target Neighborhood Hits	226	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

JAG2_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.051306 (rank : 221)
Query Neighborhood Hits	101	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

MEGF6_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.097307 (rank : 58)
Query Neighborhood Hits	101	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

SREC2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.096922 (rank : 60)
Query Neighborhood Hits	101	Target Neighborhood Hits	645	Shared Neighborhood Hits	53
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TSP1_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.137902 (rank : 33)
Query Neighborhood Hits	101	Target Neighborhood Hits	389	Shared Neighborhood Hits	74
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ZAN_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.095397 (rank : 62)
Query Neighborhood Hits	101	Target Neighborhood Hits	808	Shared Neighborhood Hits	66
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KIF12_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.005313 (rank : 239)
Query Neighborhood Hits	101	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2Z8, O35061	Gene names	Kif12
Domain Architecture
Description	Kinesin-like protein KIF12.

LTB1L_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.058847 (rank : 177)
Query Neighborhood Hits	101	Target Neighborhood Hits	514	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.061635 (rank : 166)
Query Neighborhood Hits	101	Target Neighborhood Hits	479	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MEGF8_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.075789 (rank : 112)
Query Neighborhood Hits	101	Target Neighborhood Hits	520	Shared Neighborhood Hits	45
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SEM5B_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.089381 (rank : 73)
Query Neighborhood Hits	101	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

THYG_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.017820 (rank : 236)
Query Neighborhood Hits	101	Target Neighborhood Hits	161	Shared Neighborhood Hits	21
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

KRA94_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.047989 (rank : 233)
Query Neighborhood Hits	101	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

LAMA3_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.050598 (rank : 229)
Query Neighborhood Hits	101	Target Neighborhood Hits	859	Shared Neighborhood Hits	57
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

NOTC1_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.061645 (rank : 165)
Query Neighborhood Hits	101	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ATL1_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.074695 (rank : 118)
Query Neighborhood Hits	101	Target Neighborhood Hits	93	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.070778 (rank : 129)
Query Neighborhood Hits	101	Target Neighborhood Hits	80	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL2_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.092556 (rank : 66)
Query Neighborhood Hits	101	Target Neighborhood Hits	125	Shared Neighborhood Hits	41
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.093179 (rank : 65)
Query Neighborhood Hits	101	Target Neighborhood Hits	137	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL3_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.081434 (rank : 96)
Query Neighborhood Hits	101	Target Neighborhood Hits	414	Shared Neighborhood Hits	52
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS13_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.084532 (rank : 86)
Query Neighborhood Hits	101	Target Neighborhood Hits	238	Shared Neighborhood Hits	45
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.081052 (rank : 98)
Query Neighborhood Hits	101	Target Neighborhood Hits	227	Shared Neighborhood Hits	46
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS14_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.075247 (rank : 114)
Query Neighborhood Hits	101	Target Neighborhood Hits	382	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS15_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.072198 (rank : 124)
Query Neighborhood Hits	101	Target Neighborhood Hits	151	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS18_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.086285 (rank : 80)
Query Neighborhood Hits	101	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.085904 (rank : 81)
Query Neighborhood Hits	101	Target Neighborhood Hits	163	Shared Neighborhood Hits	42
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS19_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.079398 (rank : 100)
Query Neighborhood Hits	101	Target Neighborhood Hits	203	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.082945 (rank : 87)
Query Neighborhood Hits	101	Target Neighborhood Hits	188	Shared Neighborhood Hits	39
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS2_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.081609 (rank : 94)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	44
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.075213 (rank : 115)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.078605 (rank : 104)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	45
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS4_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.070056 (rank : 132)
Query Neighborhood Hits	101	Target Neighborhood Hits	138	Shared Neighborhood Hits	37
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.070883 (rank : 128)
Query Neighborhood Hits	101	Target Neighborhood Hits	145	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS5_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.064259 (rank : 153)
Query Neighborhood Hits	101	Target Neighborhood Hits	141	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS5_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.069655 (rank : 133)
Query Neighborhood Hits	101	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS7_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.074204 (rank : 120)
Query Neighborhood Hits	101	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS8_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.072406 (rank : 123)
Query Neighborhood Hits	101	Target Neighborhood Hits	145	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS8_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.074695 (rank : 119)
Query Neighborhood Hits	101	Target Neighborhood Hits	139	Shared Neighborhood Hits	38
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS9_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.097533 (rank : 57)
Query Neighborhood Hits	101	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

C1QR1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.056756 (rank : 192)
Query Neighborhood Hits	101	Target Neighborhood Hits	493	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CI094_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.065039 (rank : 148)
Query Neighborhood Hits	101	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CO6_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.086489 (rank : 78)
Query Neighborhood Hits	101	Target Neighborhood Hits	331	Shared Neighborhood Hits	54
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.068017 (rank : 142)
Query Neighborhood Hits	101	Target Neighborhood Hits	278	Shared Neighborhood Hits	54
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.058908 (rank : 176)
Query Neighborhood Hits	101	Target Neighborhood Hits	200	Shared Neighborhood Hits	42
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.058681 (rank : 179)
Query Neighborhood Hits	101	Target Neighborhood Hits	182	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CRIM1_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.094592 (rank : 63)
Query Neighborhood Hits	101	Target Neighborhood Hits	362	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

DLL4_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.052054 (rank : 217)
Query Neighborhood Hits	101	Target Neighborhood Hits	440	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EMR1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.051094 (rank : 224)
Query Neighborhood Hits	101	Target Neighborhood Hits	382	Shared Neighborhood Hits	41
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

FBLN1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.054171 (rank : 203)
Query Neighborhood Hits	101	Target Neighborhood Hits	324	Shared Neighborhood Hits	38
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.053830 (rank : 207)
Query Neighborhood Hits	101	Target Neighborhood Hits	329	Shared Neighborhood Hits	42
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.052902 (rank : 212)
Query Neighborhood Hits	101	Target Neighborhood Hits	392	Shared Neighborhood Hits	42
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.053866 (rank : 206)
Query Neighborhood Hits	101	Target Neighborhood Hits	505	Shared Neighborhood Hits	44
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN5_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.055579 (rank : 197)
Query Neighborhood Hits	101	Target Neighborhood Hits	329	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.059197 (rank : 175)
Query Neighborhood Hits	101	Target Neighborhood Hits	317	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.072175 (rank : 125)
Query Neighborhood Hits	101	Target Neighborhood Hits	557	Shared Neighborhood Hits	59
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.070937 (rank : 127)
Query Neighborhood Hits	101	Target Neighborhood Hits	563	Shared Neighborhood Hits	56
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.064251 (rank : 154)
Query Neighborhood Hits	101	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.062244 (rank : 162)
Query Neighborhood Hits	101	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.060969 (rank : 168)
Query Neighborhood Hits	101	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR104_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.068697 (rank : 137)
Query Neighborhood Hits	101	Target Neighborhood Hits	313	Shared Neighborhood Hits	40
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR106_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.068390 (rank : 139)
Query Neighborhood Hits	101	Target Neighborhood Hits	347	Shared Neighborhood Hits	51
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.065244 (rank : 146)
Query Neighborhood Hits	101	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.055963 (rank : 196)
Query Neighborhood Hits	101	Target Neighborhood Hits	226	Shared Neighborhood Hits	35
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR412_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.052625 (rank : 215)
Query Neighborhood Hits	101	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.050307 (rank : 230)
Query Neighborhood Hits	101	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.065090 (rank : 147)
Query Neighborhood Hits	101	Target Neighborhood Hits	217	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.053559 (rank : 209)
Query Neighborhood Hits	101	Target Neighborhood Hits	231	Shared Neighborhood Hits	27
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA45_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.055521 (rank : 198)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.060316 (rank : 170)
Query Neighborhood Hits	101	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.091478 (rank : 69)
Query Neighborhood Hits	101	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.079014 (rank : 101)
Query Neighborhood Hits	101	Target Neighborhood Hits	236	Shared Neighborhood Hits	32
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA54_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.077647 (rank : 106)
Query Neighborhood Hits	101	Target Neighborhood Hits	270	Shared Neighborhood Hits	32
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.087485 (rank : 77)
Query Neighborhood Hits	101	Target Neighborhood Hits	257	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.063236 (rank : 155)
Query Neighborhood Hits	101	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.063192 (rank : 156)
Query Neighborhood Hits	101	Target Neighborhood Hits	269	Shared Neighborhood Hits	31
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.073535 (rank : 121)
Query Neighborhood Hits	101	Target Neighborhood Hits	324	Shared Neighborhood Hits	41
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.075718 (rank : 113)
Query Neighborhood Hits	101	Target Neighborhood Hits	310	Shared Neighborhood Hits	33
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.052301 (rank : 216)
Query Neighborhood Hits	101	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.057445 (rank : 187)
Query Neighborhood Hits	101	Target Neighborhood Hits	203	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA98_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.053756 (rank : 208)
Query Neighborhood Hits	101	Target Neighborhood Hits	185	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

LAMA1_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.061424 (rank : 167)
Query Neighborhood Hits	101	Target Neighborhood Hits	804	Shared Neighborhood Hits	52
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.058721 (rank : 178)
Query Neighborhood Hits	101	Target Neighborhood Hits	1092	Shared Neighborhood Hits	56
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA5_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.059201 (rank : 174)
Query Neighborhood Hits	101	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.056282 (rank : 195)
Query Neighborhood Hits	101	Target Neighborhood Hits	722	Shared Neighborhood Hits	47
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.053077 (rank : 210)
Query Neighborhood Hits	101	Target Neighborhood Hits	922	Shared Neighborhood Hits	55
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.051321 (rank : 220)
Query Neighborhood Hits	101	Target Neighborhood Hits	856	Shared Neighborhood Hits	52
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.062279 (rank : 161)
Query Neighborhood Hits	101	Target Neighborhood Hits	588	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.058061 (rank : 183)
Query Neighborhood Hits	101	Target Neighborhood Hits	624	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.054049 (rank : 204)
Query Neighborhood Hits	101	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.062001 (rank : 164)
Query Neighborhood Hits	101	Target Neighborhood Hits	58	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1F_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.056621 (rank : 193)
Query Neighborhood Hits	101	Target Neighborhood Hits	48	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LTB1L_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.056806 (rank : 191)
Query Neighborhood Hits	101	Target Neighborhood Hits	553	Shared Neighborhood Hits	45
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.056920 (rank : 190)
Query Neighborhood Hits	101	Target Neighborhood Hits	502	Shared Neighborhood Hits	45
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.064967 (rank : 151)
Query Neighborhood Hits	101	Target Neighborhood Hits	552	Shared Neighborhood Hits	53
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.050951 (rank : 226)
Query Neighborhood Hits	101	Target Neighborhood Hits	475	Shared Neighborhood Hits	45
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MEGF9_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.076531 (rank : 109)
Query Neighborhood Hits	101	Target Neighborhood Hits	557	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.077655 (rank : 105)
Query Neighborhood Hits	101	Target Neighborhood Hits	896	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MUC5B_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.056543 (rank : 194)
Query Neighborhood Hits	101	Target Neighborhood Hits	1020	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NEC1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.105735 (rank : 46)
Query Neighborhood Hits	101	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

NEC1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.105578 (rank : 47)
Query Neighborhood Hits	101	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

NEC2_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.103720 (rank : 51)
Query Neighborhood Hits	101	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.103932 (rank : 50)
Query Neighborhood Hits	101	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NELL1_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.074784 (rank : 116)
Query Neighborhood Hits	101	Target Neighborhood Hits	451	Shared Neighborhood Hits	47
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.063116 (rank : 157)
Query Neighborhood Hits	101	Target Neighborhood Hits	449	Shared Neighborhood Hits	43
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.062468 (rank : 159)
Query Neighborhood Hits	101	Target Neighborhood Hits	436	Shared Neighborhood Hits	43
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NOTC1_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.060832 (rank : 169)
Query Neighborhood Hits	101	Target Neighborhood Hits	916	Shared Neighborhood Hits	55
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.052883 (rank : 213)
Query Neighborhood Hits	101	Target Neighborhood Hits	1113	Shared Neighborhood Hits	56
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.051180 (rank : 223)
Query Neighborhood Hits	101	Target Neighborhood Hits	975	Shared Neighborhood Hits	58
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.050648 (rank : 228)
Query Neighborhood Hits	101	Target Neighborhood Hits	905	Shared Neighborhood Hits	52
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

PCSK4_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.116722 (rank : 39)
Query Neighborhood Hits	101	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PCSK4_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.107919 (rank : 44)
Query Neighborhood Hits	101	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

PCSK7_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.103308 (rank : 52)
Query Neighborhood Hits	101	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

PCSK7_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.103246 (rank : 53)
Query Neighborhood Hits	101	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

SEM5A_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.085743 (rank : 82)
Query Neighborhood Hits	101	Target Neighborhood Hits	177	Shared Neighborhood Hits	46
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.088429 (rank : 74)
Query Neighborhood Hits	101	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SREC_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.091088 (rank : 70)
Query Neighborhood Hits	101	Target Neighborhood Hits	645	Shared Neighborhood Hits	61
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.052999 (rank : 211)
Query Neighborhood Hits	101	Target Neighborhood Hits	546	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.052809 (rank : 214)
Query Neighborhood Hits	101	Target Neighborhood Hits	566	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.050745 (rank : 227)
Query Neighborhood Hits	101	Target Neighborhood Hits	534	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.051265 (rank : 222)
Query Neighborhood Hits	101	Target Neighborhood Hits	528	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TECTA_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.050193 (rank : 232)
Query Neighborhood Hits	101	Target Neighborhood Hits	244	Shared Neighborhood Hits	37
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

THSD1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.081921 (rank : 93)
Query Neighborhood Hits	101	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.081496 (rank : 95)
Query Neighborhood Hits	101	Target Neighborhood Hits	153	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TNR16_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.069157 (rank : 136)
Query Neighborhood Hits	101	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.068259 (rank : 141)
Query Neighborhood Hits	101	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR1A_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.058268 (rank : 182)
Query Neighborhood Hits	101	Target Neighborhood Hits	121	Shared Neighborhood Hits	21
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR1B_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.058675 (rank : 180)
Query Neighborhood Hits	101	Target Neighborhood Hits	127	Shared Neighborhood Hits	26
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.057979 (rank : 184)
Query Neighborhood Hits	101	Target Neighborhood Hits	123	Shared Neighborhood Hits	23
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR21_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.057394 (rank : 188)
Query Neighborhood Hits	101	Target Neighborhood Hits	90	Shared Neighborhood Hits	25
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.054249 (rank : 201)
Query Neighborhood Hits	101	Target Neighborhood Hits	108	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR23_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.062349 (rank : 160)
Query Neighborhood Hits	101	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR25_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.070626 (rank : 130)
Query Neighborhood Hits	101	Target Neighborhood Hits	172	Shared Neighborhood Hits	32
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR3_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.057562 (rank : 185)
Query Neighborhood Hits	101	Target Neighborhood Hits	145	Shared Neighborhood Hits	24
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR3_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.054237 (rank : 202)
Query Neighborhood Hits	101	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR4_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.054285 (rank : 200)
Query Neighborhood Hits	101	Target Neighborhood Hits	152	Shared Neighborhood Hits	29
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR4_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.058331 (rank : 181)
Query Neighborhood Hits	101	Target Neighborhood Hits	137	Shared Neighborhood Hits	28
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR5_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.065028 (rank : 149)
Query Neighborhood Hits	101	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR6_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.052054 (rank : 218)
Query Neighborhood Hits	101	Target Neighborhood Hits	99	Shared Neighborhood Hits	23
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.057516 (rank : 186)
Query Neighborhood Hits	101	Target Neighborhood Hits	120	Shared Neighborhood Hits	27
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR8_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.050968 (rank : 225)
Query Neighborhood Hits	101	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR9_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.069158 (rank : 135)
Query Neighborhood Hits	101	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR9_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.073204 (rank : 122)
Query Neighborhood Hits	101	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

UNC5A_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.051579 (rank : 219)
Query Neighborhood Hits	101	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.086484 (rank : 79)
Query Neighborhood Hits	101	Target Neighborhood Hits	203	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5C_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.082916 (rank : 88)
Query Neighborhood Hits	101	Target Neighborhood Hits	226	Shared Neighborhood Hits	38
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.082871 (rank : 89)
Query Neighborhood Hits	101	Target Neighborhood Hits	225	Shared Neighborhood Hits	38
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.077447 (rank : 107)
Query Neighborhood Hits	101	Target Neighborhood Hits	267	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.077299 (rank : 108)
Query Neighborhood Hits	101	Target Neighborhood Hits	268	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

USH2A_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.055512 (rank : 199)
Query Neighborhood Hits	101	Target Neighborhood Hits	626	Shared Neighborhood Hits	47
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VWF_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.069590 (rank : 134)
Query Neighborhood Hits	101	Target Neighborhood Hits	396	Shared Neighborhood Hits	53
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.071255 (rank : 126)
Query Neighborhood Hits	101	Target Neighborhood Hits	381	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WIF1_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.059713 (rank : 173)
Query Neighborhood Hits	101	Target Neighborhood Hits	392	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.060146 (rank : 171)
Query Neighborhood Hits	101	Target Neighborhood Hits	393	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

Hits sorted by NC score

RSPO1_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.42253e-146 (rank : 1)
Query Neighborhood Hits	101	Target Neighborhood Hits	101	Shared Neighborhood Hits	101
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
NC score	0.988062 (rank : 2)	θ value	6.41512e-131 (rank : 2)
Query Neighborhood Hits	101	Target Neighborhood Hits	85	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO3_MOUSE
NC score	0.953322 (rank : 3)	θ value	3.71096e-62 (rank : 3)
Query Neighborhood Hits	101	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO3_HUMAN
NC score	0.948482 (rank : 4)	θ value	6.32992e-62 (rank : 4)
Query Neighborhood Hits	101	Target Neighborhood Hits	128	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO2_HUMAN
NC score	0.934779 (rank : 5)	θ value	2.25659e-51 (rank : 5)
Query Neighborhood Hits	101	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
NC score	0.933958 (rank : 6)	θ value	3.84914e-51 (rank : 6)
Query Neighborhood Hits	101	Target Neighborhood Hits	88	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO4_HUMAN
NC score	0.909750 (rank : 7)	θ value	1.2411e-41 (rank : 7)
Query Neighborhood Hits	101	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
NC score	0.907532 (rank : 8)	θ value	5.39604e-37 (rank : 8)
Query Neighborhood Hits	101	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SPON2_HUMAN
NC score	0.313188 (rank : 9)	θ value	0.00175202 (rank : 18)
Query Neighborhood Hits	101	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

PCSK6_HUMAN
NC score	0.312790 (rank : 10)	θ value	1.38499e-08 (rank : 11)
Query Neighborhood Hits	101	Target Neighborhood Hits	298	Shared Neighborhood Hits	56
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PCSK5_HUMAN
NC score	0.306858 (rank : 11)	θ value	8.11959e-09 (rank : 10)
Query Neighborhood Hits	101	Target Neighborhood Hits	291	Shared Neighborhood Hits	64
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

SPON1_MOUSE
NC score	0.305342 (rank : 12)	θ value	5.44631e-05 (rank : 15)
Query Neighborhood Hits	101	Target Neighborhood Hits	123	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
NC score	0.304796 (rank : 13)	θ value	4.1701e-05 (rank : 14)
Query Neighborhood Hits	101	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON2_MOUSE
NC score	0.303294 (rank : 14)	θ value	0.00665767 (rank : 19)
Query Neighborhood Hits	101	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

PCSK5_MOUSE
NC score	0.303110 (rank : 15)	θ value	1.33837e-11 (rank : 9)
Query Neighborhood Hits	101	Target Neighborhood Hits	613	Shared Neighborhood Hits	76
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

FRAS1_MOUSE
NC score	0.256421 (rank : 16)	θ value	1.09739e-05 (rank : 13)
Query Neighborhood Hits	101	Target Neighborhood Hits	747	Shared Neighborhood Hits	81
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_HUMAN
NC score	0.254600 (rank : 17)	θ value	1.09739e-05 (rank : 12)
Query Neighborhood Hits	101	Target Neighborhood Hits	759	Shared Neighborhood Hits	81
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PROP_MOUSE
NC score	0.216539 (rank : 18)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	101	Target Neighborhood Hits	165	Shared Neighborhood Hits	51
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROP_HUMAN
NC score	0.201906 (rank : 19)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	101	Target Neighborhood Hits	126	Shared Neighborhood Hits	53
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

SSPO_MOUSE
NC score	0.185380 (rank : 20)	θ value	0.000602161 (rank : 16)
Query Neighborhood Hits	101	Target Neighborhood Hits	800	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TNR6B_HUMAN
NC score	0.178360 (rank : 21)	θ value	0.000786445 (rank : 17)
Query Neighborhood Hits	101	Target Neighborhood Hits	103	Shared Neighborhood Hits	32
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

BAI2_HUMAN
NC score	0.170762 (rank : 22)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	101	Target Neighborhood Hits	332	Shared Neighborhood Hits	52
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
NC score	0.170322 (rank : 23)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	101	Target Neighborhood Hits	323	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

FURIN_HUMAN
NC score	0.168277 (rank : 24)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	101	Target Neighborhood Hits	52	Shared Neighborhood Hits	21
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

FURIN_MOUSE
NC score	0.163338 (rank : 25)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	101	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

BAI3_HUMAN
NC score	0.158142 (rank : 26)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	101	Target Neighborhood Hits	246	Shared Neighborhood Hits	52
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
NC score	0.157912 (rank : 27)	θ value	0.0148317 (rank : 21)
Query Neighborhood Hits	101	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI1_HUMAN
NC score	0.157066 (rank : 28)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	101	Target Neighborhood Hits	375	Shared Neighborhood Hits	52
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
NC score	0.151697 (rank : 29)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	101	Target Neighborhood Hits	340	Shared Neighborhood Hits	47
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CILP1_HUMAN
NC score	0.146941 (rank : 30)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	101	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP2_HUMAN
NC score	0.142671 (rank : 31)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	101	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

TSP1_MOUSE
NC score	0.138970 (rank : 32)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	101	Target Neighborhood Hits	396	Shared Neighborhood Hits	75
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_HUMAN
NC score	0.137902 (rank : 33)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	101	Target Neighborhood Hits	389	Shared Neighborhood Hits	74
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
NC score	0.133903 (rank : 34)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	101	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
NC score	0.133319 (rank : 35)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	101	Target Neighborhood Hits	352	Shared Neighborhood Hits	69
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

CILP1_MOUSE
NC score	0.128306 (rank : 36)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	101	Target Neighborhood Hits	282	Shared Neighborhood Hits	41
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CREL1_MOUSE
NC score	0.127554 (rank : 37)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	101	Target Neighborhood Hits	524	Shared Neighborhood Hits	49
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_HUMAN
NC score	0.123911 (rank : 38)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	101	Target Neighborhood Hits	441	Shared Neighborhood Hits	46
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

PCSK4_HUMAN
NC score	0.116722 (rank : 39)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	101	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

TNR5_MOUSE
NC score	0.116388 (rank : 40)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	101	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

BMPER_HUMAN
NC score	0.112739 (rank : 41)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	101	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

ATS16_MOUSE
NC score	0.112616 (rank : 42)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	47
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS20_MOUSE
NC score	0.109578 (rank : 43)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	101	Target Neighborhood Hits	225	Shared Neighborhood Hits	53
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

PCSK4_MOUSE
NC score	0.107919 (rank : 44)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	101	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

TR11B_HUMAN
NC score	0.107086 (rank : 45)	θ value	0.0736092 (rank : 34)
Query Neighborhood Hits	101	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

NEC1_HUMAN
NC score	0.105735 (rank : 46)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	101	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

NEC1_MOUSE
NC score	0.105578 (rank : 47)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	101	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

ATS17_HUMAN
NC score	0.104969 (rank : 48)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS16_HUMAN
NC score	0.104785 (rank : 49)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	101	Target Neighborhood Hits	208	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

NEC2_MOUSE
NC score	0.103932 (rank : 50)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	101	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_HUMAN
NC score	0.103720 (rank : 51)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	101	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

PCSK7_HUMAN
NC score	0.103308 (rank : 52)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	101	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

PCSK7_MOUSE
NC score	0.103246 (rank : 53)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	101	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

TNR14_HUMAN
NC score	0.103214 (rank : 54)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	101	Target Neighborhood Hits	149	Shared Neighborhood Hits	36
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ATS20_HUMAN
NC score	0.102889 (rank : 55)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	101	Target Neighborhood Hits	192	Shared Neighborhood Hits	53
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

HMCN1_HUMAN
NC score	0.102077 (rank : 56)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	101	Target Neighborhood Hits	983	Shared Neighborhood Hits	82
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ATS9_HUMAN
NC score	0.097533 (rank : 57)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	101	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

MEGF6_HUMAN
NC score	0.097307 (rank : 58)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	101	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

BMPER_MOUSE
NC score	0.096930 (rank : 59)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

SREC2_HUMAN
NC score	0.096922 (rank : 60)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	101	Target Neighborhood Hits	645	Shared Neighborhood Hits	53
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ATL5_HUMAN
NC score	0.095844 (rank : 61)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	101	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ZAN_MOUSE
NC score	0.095397 (rank : 62)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	101	Target Neighborhood Hits	808	Shared Neighborhood Hits	66
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CRIM1_HUMAN
NC score	0.094592 (rank : 63)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	101	Target Neighborhood Hits	362	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

SREC2_MOUSE
NC score	0.094300 (rank : 64)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	101	Target Neighborhood Hits	605	Shared Neighborhood Hits	55
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ATL2_MOUSE
NC score	0.093179 (rank : 65)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	101	Target Neighborhood Hits	137	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL2_HUMAN
NC score	0.092556 (rank : 66)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	101	Target Neighborhood Hits	125	Shared Neighborhood Hits	41
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

UNC5B_MOUSE
NC score	0.092044 (rank : 67)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	101	Target Neighborhood Hits	226	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
NC score	0.091900 (rank : 68)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	101	Target Neighborhood Hits	225	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

KRA51_HUMAN
NC score	0.091478 (rank : 69)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	101	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SREC_HUMAN
NC score	0.091088 (rank : 70)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	101	Target Neighborhood Hits	645	Shared Neighborhood Hits	61
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ATS12_MOUSE
NC score	0.090219 (rank : 71)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	101	Target Neighborhood Hits	220	Shared Neighborhood Hits	43
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

CO8B_MOUSE
NC score	0.089972 (rank : 72)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	101	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

SEM5B_MOUSE
NC score	0.089381 (rank : 73)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	101	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5A_MOUSE
NC score	0.088429 (rank : 74)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	101	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_HUMAN
NC score	0.088131 (rank : 75)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	101	Target Neighborhood Hits	178	Shared Neighborhood Hits	47
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ATS12_HUMAN
NC score	0.087981 (rank : 76)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	101	Target Neighborhood Hits	251	Shared Neighborhood Hits	43
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

KRA55_HUMAN
NC score	0.087485 (rank : 77)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	101	Target Neighborhood Hits	257	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

CO6_HUMAN
NC score	0.086489 (rank : 78)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	101	Target Neighborhood Hits	331	Shared Neighborhood Hits	54
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

UNC5A_MOUSE
NC score	0.086484 (rank : 79)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	101	Target Neighborhood Hits	203	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ATS18_HUMAN
NC score	0.086285 (rank : 80)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	101	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
NC score	0.085904 (rank : 81)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	101	Target Neighborhood Hits	163	Shared Neighborhood Hits	42
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

SEM5A_HUMAN
NC score	0.085743 (rank : 82)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	101	Target Neighborhood Hits	177	Shared Neighborhood Hits	46
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

CO8B_HUMAN
NC score	0.085412 (rank : 83)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	101	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

TR11B_MOUSE
NC score	0.084723 (rank : 84)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	101	Target Neighborhood Hits	95	Shared Neighborhood Hits	18
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

KRA53_HUMAN
NC score	0.084715 (rank : 85)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	101	Target Neighborhood Hits	331	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

ATS13_HUMAN
NC score	0.084532 (rank : 86)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	101	Target Neighborhood Hits	238	Shared Neighborhood Hits	45
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS19_MOUSE
NC score	0.082945 (rank : 87)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	101	Target Neighborhood Hits	188	Shared Neighborhood Hits	39
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

UNC5C_HUMAN
NC score	0.082916 (rank : 88)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	101	Target Neighborhood Hits	226	Shared Neighborhood Hits	38
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
NC score	0.082871 (rank : 89)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	101	Target Neighborhood Hits	225	Shared Neighborhood Hits	38
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

SCUB3_MOUSE
NC score	0.082469 (rank : 90)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	101	Target Neighborhood Hits	442	Shared Neighborhood Hits	51
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LTBP4_MOUSE
NC score	0.082400 (rank : 91)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	101	Target Neighborhood Hits	607	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TNR22_MOUSE
NC score	0.082379 (rank : 92)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	101	Target Neighborhood Hits	97	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

THSD1_HUMAN
NC score	0.081921 (rank : 93)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	101	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ATS2_HUMAN
NC score	0.081609 (rank : 94)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	44
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

THSD1_MOUSE
NC score	0.081496 (rank : 95)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	101	Target Neighborhood Hits	153	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ATL3_HUMAN
NC score	0.081434 (rank : 96)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	101	Target Neighborhood Hits	414	Shared Neighborhood Hits	52
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS1_MOUSE
NC score	0.081425 (rank : 97)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	101	Target Neighborhood Hits	158	Shared Neighborhood Hits	41
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS13_MOUSE
NC score	0.081052 (rank : 98)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	101	Target Neighborhood Hits	227	Shared Neighborhood Hits	46
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

TNR26_MOUSE
NC score	0.079889 (rank : 99)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	101	Target Neighborhood Hits	106	Shared Neighborhood Hits	23
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

ATS19_HUMAN
NC score	0.079398 (rank : 100)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	101	Target Neighborhood Hits	203	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

KRA52_HUMAN
NC score	0.079014 (rank : 101)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	101	Target Neighborhood Hits	236	Shared Neighborhood Hits	32
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

MEGF8_HUMAN
NC score	0.078831 (rank : 102)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	101	Target Neighborhood Hits	528	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

ATS6_HUMAN
NC score	0.078658 (rank : 103)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	101	Target Neighborhood Hits	141	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS3_HUMAN
NC score	0.078605 (rank : 104)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	45
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

MEGF9_MOUSE
NC score	0.077655 (rank : 105)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	101	Target Neighborhood Hits	896	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KRA54_HUMAN
NC score	0.077647 (rank : 106)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	101	Target Neighborhood Hits	270	Shared Neighborhood Hits	32
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

UNC5D_HUMAN
NC score	0.077447 (rank : 107)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	101	Target Neighborhood Hits	267	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.077299 (rank : 108)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	101	Target Neighborhood Hits	268	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

MEGF9_HUMAN
NC score	0.076531 (rank : 109)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	101	Target Neighborhood Hits	557	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ATS1_HUMAN
NC score	0.076522 (rank : 110)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	101	Target Neighborhood Hits	159	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

LTBP2_MOUSE
NC score	0.076431 (rank : 111)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	101	Target Neighborhood Hits	617	Shared Neighborhood Hits	51
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MEGF8_MOUSE
NC score	0.075789 (rank : 112)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	101	Target Neighborhood Hits	520	Shared Neighborhood Hits	45
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KRA59_HUMAN
NC score	0.075718 (rank : 113)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	101	Target Neighborhood Hits	310	Shared Neighborhood Hits	33
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

ATS14_HUMAN
NC score	0.075247 (rank : 114)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	101	Target Neighborhood Hits	382	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS2_MOUSE
NC score	0.075213 (rank : 115)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

NELL1_HUMAN
NC score	0.074784 (rank : 116)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	101	Target Neighborhood Hits	451	Shared Neighborhood Hits	47
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SCUB3_HUMAN
NC score	0.074740 (rank : 117)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	101	Target Neighborhood Hits	428	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ATL1_HUMAN
NC score	0.074695 (rank : 118)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	101	Target Neighborhood Hits	93	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATS8_MOUSE
NC score	0.074695 (rank : 119)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	101	Target Neighborhood Hits	139	Shared Neighborhood Hits	38
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS7_HUMAN
NC score	0.074204 (rank : 120)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	101	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

KRA58_HUMAN
NC score	0.073535 (rank : 121)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	101	Target Neighborhood Hits	324	Shared Neighborhood Hits	41
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

TNR9_MOUSE
NC score	0.073204 (rank : 122)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	101	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

ATS8_HUMAN
NC score	0.072406 (rank : 123)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	101	Target Neighborhood Hits	145	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS15_HUMAN
NC score	0.072198 (rank : 124)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	101	Target Neighborhood Hits	151	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

FBN1_HUMAN
NC score	0.072175 (rank : 125)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	101	Target Neighborhood Hits	557	Shared Neighborhood Hits	59
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

VWF_MOUSE
NC score	0.071255 (rank : 126)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	101	Target Neighborhood Hits	381	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FBN1_MOUSE
NC score	0.070937 (rank : 127)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	101	Target Neighborhood Hits	563	Shared Neighborhood Hits	56
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

ATS4_MOUSE
NC score	0.070883 (rank : 128)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	101	Target Neighborhood Hits	145	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATL1_MOUSE
NC score	0.070778 (rank : 129)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	101	Target Neighborhood Hits	80	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

TNR25_HUMAN
NC score	0.070626 (rank : 130)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	101	Target Neighborhood Hits	172	Shared Neighborhood Hits	32
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

INSRR_HUMAN
NC score	0.070113 (rank : 131)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	101	Target Neighborhood Hits	950	Shared Neighborhood Hits	38
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

ATS4_HUMAN
NC score	0.070056 (rank : 132)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	101	Target Neighborhood Hits	138	Shared Neighborhood Hits	37
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS5_MOUSE
NC score	0.069655 (rank : 133)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	101	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

VWF_HUMAN
NC score	0.069590 (rank : 134)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	101	Target Neighborhood Hits	396	Shared Neighborhood Hits	53
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

TNR9_HUMAN
NC score	0.069158 (rank : 135)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	101	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR16_HUMAN
NC score	0.069157 (rank : 136)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	101	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

KR104_HUMAN
NC score	0.068697 (rank : 137)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	101	Target Neighborhood Hits	313	Shared Neighborhood Hits	40
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

IGF1R_MOUSE
NC score	0.068583 (rank : 138)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	101	Target Neighborhood Hits	973	Shared Neighborhood Hits	42
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KR106_HUMAN
NC score	0.068390 (rank : 139)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	101	Target Neighborhood Hits	347	Shared Neighborhood Hits	51
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LAMA5_HUMAN
NC score	0.068274 (rank : 140)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	101	Target Neighborhood Hits	976	Shared Neighborhood Hits	62
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

TNR16_MOUSE
NC score	0.068259 (rank : 141)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	101	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

CO7_HUMAN
NC score	0.068017 (rank : 142)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	101	Target Neighborhood Hits	278	Shared Neighborhood Hits	54
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

IGF1R_HUMAN
NC score	0.067802 (rank : 143)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	101	Target Neighborhood Hits	977	Shared Neighborhood Hits	42
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_MOUSE
NC score	0.067673 (rank : 144)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	101	Target Neighborhood Hits	961	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

TNR1A_MOUSE
NC score	0.067604 (rank : 145)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	101	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

KR107_HUMAN
NC score	0.065244 (rank : 146)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	101	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR510_HUMAN
NC score	0.065090 (rank : 147)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	101	Target Neighborhood Hits	217	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

CI094_HUMAN
NC score	0.065039 (rank : 148)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	101	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

TNR5_HUMAN
NC score	0.065028 (rank : 149)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	101	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

INSR_MOUSE
NC score	0.064987 (rank : 150)	θ value	0.0193708 (rank : 22)
Query Neighborhood Hits	101	Target Neighborhood Hits	968	Shared Neighborhood Hits	35
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

LTBP2_HUMAN
NC score	0.064967 (rank : 151)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	101	Target Neighborhood Hits	552	Shared Neighborhood Hits	53
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN2_MOUSE
NC score	0.064712 (rank : 152)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	101	Target Neighborhood Hits	549	Shared Neighborhood Hits	52
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

ATS5_HUMAN
NC score	0.064259 (rank : 153)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	101	Target Neighborhood Hits	141	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

FBN2_HUMAN
NC score	0.064251 (rank : 154)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	101	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

KRA56_HUMAN
NC score	0.063236 (rank : 155)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	101	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
NC score	0.063192 (rank : 156)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	101	Target Neighborhood Hits	269	Shared Neighborhood Hits	31
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NELL2_HUMAN
NC score	0.063116 (rank : 157)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	101	Target Neighborhood Hits	449	Shared Neighborhood Hits	43
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

INSR_HUMAN
NC score	0.062707 (rank : 158)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	101	Target Neighborhood Hits	963	Shared Neighborhood Hits	36
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

NELL2_MOUSE
NC score	0.062468 (rank : 159)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	101	Target Neighborhood Hits	436	Shared Neighborhood Hits	43
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

TNR23_MOUSE
NC score	0.062349 (rank : 160)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	101	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

LAMC3_HUMAN
NC score	0.062279 (rank : 161)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	101	Target Neighborhood Hits	588	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

FBN3_HUMAN
NC score	0.062244 (rank : 162)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	101	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LAMB2_HUMAN
NC score	0.062075 (rank : 163)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	101	Target Neighborhood Hits	692	Shared Neighborhood Hits	48
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LCE1B_HUMAN
NC score	0.062001 (rank : 164)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	101	Target Neighborhood Hits	58	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

NOTC1_HUMAN
NC score	0.061645 (rank : 165)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	101	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LTB1S_MOUSE
NC score	0.061635 (rank : 166)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	101	Target Neighborhood Hits	479	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LAMA1_HUMAN
NC score	0.061424 (rank : 167)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	101	Target Neighborhood Hits	804	Shared Neighborhood Hits	52
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KR101_HUMAN
NC score	0.060969 (rank : 168)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	101	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

NOTC1_MOUSE
NC score	0.060832 (rank : 169)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	101	Target Neighborhood Hits	916	Shared Neighborhood Hits	55
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KRA47_HUMAN
NC score	0.060316 (rank : 170)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	101	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

WIF1_MOUSE
NC score	0.060146 (rank : 171)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	101	Target Neighborhood Hits	393	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LAMA1_MOUSE
NC score	0.059871 (rank : 172)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	101	Target Neighborhood Hits	838	Shared Neighborhood Hits	58
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

WIF1_HUMAN
NC score	0.059713 (rank : 173)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	101	Target Neighborhood Hits	392	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LAMA5_MOUSE
NC score	0.059201 (rank : 174)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	101	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FBLN5_MOUSE
NC score	0.059197 (rank : 175)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	101	Target Neighborhood Hits	317	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

CO8A_HUMAN
NC score	0.058908 (rank : 176)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	101	Target Neighborhood Hits	200	Shared Neighborhood Hits	42
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

LTB1L_MOUSE
NC score	0.058847 (rank : 177)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	101	Target Neighborhood Hits	514	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LAMA2_HUMAN
NC score	0.058721 (rank : 178)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	101	Target Neighborhood Hits	1092	Shared Neighborhood Hits	56
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CO8A_MOUSE
NC score	0.058681 (rank : 179)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	101	Target Neighborhood Hits	182	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TNR1B_HUMAN
NC score	0.058675 (rank : 180)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	101	Target Neighborhood Hits	127	Shared Neighborhood Hits	26
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR4_MOUSE
NC score	0.058331 (rank : 181)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	101	Target Neighborhood Hits	137	Shared Neighborhood Hits	28
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR1A_HUMAN
NC score	0.058268 (rank : 182)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	101	Target Neighborhood Hits	121	Shared Neighborhood Hits	21
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

LAMC3_MOUSE
NC score	0.058061 (rank : 183)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	101	Target Neighborhood Hits	624	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

TNR1B_MOUSE
NC score	0.057979 (rank : 184)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	101	Target Neighborhood Hits	123	Shared Neighborhood Hits	23
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR3_HUMAN
NC score	0.057562 (rank : 185)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	101	Target Neighborhood Hits	145	Shared Neighborhood Hits	24
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR7_HUMAN
NC score	0.057516 (rank : 186)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	101	Target Neighborhood Hits	120	Shared Neighborhood Hits	27
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

KRA93_HUMAN
NC score	0.057445 (rank : 187)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	101	Target Neighborhood Hits	203	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

TNR21_HUMAN
NC score	0.057394 (rank : 188)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	101	Target Neighborhood Hits	90	Shared Neighborhood Hits	25
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

LAMA2_MOUSE
NC score	0.057120 (rank : 189)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	101	Target Neighborhood Hits	1198	Shared Neighborhood Hits	54
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LTB1S_HUMAN
NC score	0.056920 (rank : 190)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	101	Target Neighborhood Hits	502	Shared Neighborhood Hits	45
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.056806 (rank : 191)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	101	Target Neighborhood Hits	553	Shared Neighborhood Hits	45
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

C1QR1_HUMAN
NC score	0.056756 (rank : 192)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	101	Target Neighborhood Hits	493	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

LCE1F_HUMAN
NC score	0.056621 (rank : 193)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	101	Target Neighborhood Hits	48	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

MUC5B_HUMAN
NC score	0.056543 (rank : 194)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	101	Target Neighborhood Hits	1020	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

LAMB2_MOUSE
NC score	0.056282 (rank : 195)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	101	Target Neighborhood Hits	722	Shared Neighborhood Hits	47
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

KR108_HUMAN
NC score	0.055963 (rank : 196)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	101	Target Neighborhood Hits	226	Shared Neighborhood Hits	35
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

FBLN5_HUMAN
NC score	0.055579 (rank : 197)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	101	Target Neighborhood Hits	329	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

KRA45_HUMAN
NC score	0.055521 (rank : 198)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

USH2A_MOUSE
NC score	0.055512 (rank : 199)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	101	Target Neighborhood Hits	626	Shared Neighborhood Hits	47
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

TNR4_HUMAN
NC score	0.054285 (rank : 200)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	101	Target Neighborhood Hits	152	Shared Neighborhood Hits	29
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR21_MOUSE
NC score	0.054249 (rank : 201)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	101	Target Neighborhood Hits	108	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR3_MOUSE
NC score	0.054237 (rank : 202)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	101	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

FBLN1_HUMAN
NC score	0.054171 (rank : 203)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	101	Target Neighborhood Hits	324	Shared Neighborhood Hits	38
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LCE1A_HUMAN
NC score	0.054049 (rank : 204)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	101	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

NOTC3_HUMAN
NC score	0.053913 (rank : 205)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	101	Target Neighborhood Hits	1062	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBLN2_MOUSE
NC score	0.053866 (rank : 206)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	101	Target Neighborhood Hits	505	Shared Neighborhood Hits	44
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN1_MOUSE
NC score	0.053830 (rank : 207)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	101	Target Neighborhood Hits	329	Shared Neighborhood Hits	42
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

KRA98_HUMAN
NC score	0.053756 (rank : 208)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	101	Target Neighborhood Hits	185	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KR511_HUMAN
NC score	0.053559 (rank : 209)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	101	Target Neighborhood Hits	231	Shared Neighborhood Hits	27
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

LAMC1_HUMAN
NC score	0.053077 (rank : 210)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	101	Target Neighborhood Hits	922	Shared Neighborhood Hits	55
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

STAB1_HUMAN
NC score	0.052999 (rank : 211)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	101	Target Neighborhood Hits	546	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

FBLN2_HUMAN
NC score	0.052902 (rank : 212)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	101	Target Neighborhood Hits	392	Shared Neighborhood Hits	42
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

NOTC2_HUMAN
NC score	0.052883 (rank : 213)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	101	Target Neighborhood Hits	1113	Shared Neighborhood Hits	56
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

STAB1_MOUSE
NC score	0.052809 (rank : 214)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	101	Target Neighborhood Hits	566	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

KR412_HUMAN
NC score	0.052625 (rank : 215)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	101	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA92_HUMAN
NC score	0.052301 (rank : 216)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	101	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

DLL4_MOUSE
NC score	0.052054 (rank : 217)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	101	Target Neighborhood Hits	440	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

TNR6_MOUSE
NC score	0.052054 (rank : 218)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	101	Target Neighborhood Hits	99	Shared Neighborhood Hits	23
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

UNC5A_HUMAN
NC score	0.051579 (rank : 219)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	101	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

LAMC1_MOUSE
NC score	0.051321 (rank : 220)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	101	Target Neighborhood Hits	856	Shared Neighborhood Hits	52
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

JAG2_HUMAN
NC score	0.051306 (rank : 221)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	101	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

STAB2_MOUSE
NC score	0.051265 (rank : 222)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	101	Target Neighborhood Hits	528	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

NOTC3_MOUSE
NC score	0.051180 (rank : 223)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	101	Target Neighborhood Hits	975	Shared Neighborhood Hits	58
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

EMR1_HUMAN
NC score	0.051094 (rank : 224)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	101	Target Neighborhood Hits	382	Shared Neighborhood Hits	41
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

TNR8_HUMAN
NC score	0.050968 (rank : 225)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	101	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

LTBP3_MOUSE
NC score	0.050951 (rank : 226)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	101	Target Neighborhood Hits	475	Shared Neighborhood Hits	45
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

STAB2_HUMAN
NC score	0.050745 (rank : 227)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	101	Target Neighborhood Hits	534	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

NOTC4_HUMAN
NC score	0.050648 (rank : 228)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	101	Target Neighborhood Hits	905	Shared Neighborhood Hits	52
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

LAMA3_MOUSE
NC score	0.050598 (rank : 229)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	101	Target Neighborhood Hits	859	Shared Neighborhood Hits	57
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

KR414_HUMAN
NC score	0.050307 (rank : 230)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	101	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

DLL3_MOUSE
NC score	0.050253 (rank : 231)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	101	Target Neighborhood Hits	399	Shared Neighborhood Hits	40
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

TECTA_MOUSE
NC score	0.050193 (rank : 232)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	101	Target Neighborhood Hits	244	Shared Neighborhood Hits	37
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

KRA94_HUMAN
NC score	0.047989 (rank : 233)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	101	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

EGFR_MOUSE
NC score	0.030007 (rank : 234)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	101	Target Neighborhood Hits	927	Shared Neighborhood Hits	34
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ODFP_MOUSE
NC score	0.029240 (rank : 235)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	101	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

THYG_MOUSE
NC score	0.017820 (rank : 236)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	101	Target Neighborhood Hits	161	Shared Neighborhood Hits	21
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

LHX4_MOUSE
NC score	0.017280 (rank : 237)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	101	Target Neighborhood Hits	457	Shared Neighborhood Hits	7
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LHX4_HUMAN
NC score	0.017274 (rank : 238)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	101	Target Neighborhood Hits	455	Shared Neighborhood Hits	7
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

KIF12_MOUSE
NC score	0.005313 (rank : 239)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	101	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2Z8, O35061	Gene names	Kif12
Domain Architecture
Description	Kinesin-like protein KIF12.