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Network neighborhood for query Sequence : RECQ4_MOUSE

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RECQ4_MOUSE
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RECQ4_HUMAN
θ value	0 (rank : 1)	NC score	0.966352 (rank : 2)
Query Neighborhood Hits	206	Target Neighborhood Hits	177	Shared Neighborhood Hits	94
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	206	Target Neighborhood Hits	206	Shared Neighborhood Hits	206
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RECQ5_HUMAN
θ value	2.04573e-44 (rank : 3)	NC score	0.803849 (rank : 7)
Query Neighborhood Hits	206	Target Neighborhood Hits	390	Shared Neighborhood Hits	86
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

BLM_HUMAN
θ value	8.59492e-43 (rank : 4)	NC score	0.811873 (rank : 6)
Query Neighborhood Hits	206	Target Neighborhood Hits	148	Shared Neighborhood Hits	75
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	8.59492e-43 (rank : 5)	NC score	0.817452 (rank : 5)
Query Neighborhood Hits	206	Target Neighborhood Hits	108	Shared Neighborhood Hits	73
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

RECQ1_HUMAN
θ value	5.57106e-42 (rank : 6)	NC score	0.827957 (rank : 4)
Query Neighborhood Hits	206	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
θ value	7.27602e-42 (rank : 7)	NC score	0.828771 (rank : 3)
Query Neighborhood Hits	206	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_HUMAN
θ value	5.21438e-40 (rank : 8)	NC score	0.799419 (rank : 8)
Query Neighborhood Hits	206	Target Neighborhood Hits	132	Shared Neighborhood Hits	83
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
θ value	4.88048e-38 (rank : 9)	NC score	0.783924 (rank : 9)
Query Neighborhood Hits	206	Target Neighborhood Hits	295	Shared Neighborhood Hits	84
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DDX5_HUMAN
θ value	3.07829e-16 (rank : 10)	NC score	0.603817 (rank : 11)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	6.85773e-16 (rank : 11)	NC score	0.603865 (rank : 10)
Query Neighborhood Hits	206	Target Neighborhood Hits	101	Shared Neighborhood Hits	83
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX43_HUMAN
θ value	5.8054e-15 (rank : 12)	NC score	0.594850 (rank : 14)
Query Neighborhood Hits	206	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX17_HUMAN
θ value	1.42992e-13 (rank : 13)	NC score	0.601538 (rank : 13)
Query Neighborhood Hits	206	Target Neighborhood Hits	104	Shared Neighborhood Hits	83
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	1.42992e-13 (rank : 14)	NC score	0.601594 (rank : 12)
Query Neighborhood Hits	206	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX46_HUMAN
θ value	4.16044e-13 (rank : 15)	NC score	0.588694 (rank : 15)
Query Neighborhood Hits	206	Target Neighborhood Hits	357	Shared Neighborhood Hits	90
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	4.16044e-13 (rank : 16)	NC score	0.587719 (rank : 16)
Query Neighborhood Hits	206	Target Neighborhood Hits	358	Shared Neighborhood Hits	91
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX53_HUMAN
θ value	3.29651e-10 (rank : 17)	NC score	0.567976 (rank : 19)
Query Neighborhood Hits	206	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX41_HUMAN
θ value	7.34386e-10 (rank : 18)	NC score	0.575999 (rank : 17)
Query Neighborhood Hits	206	Target Neighborhood Hits	111	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	1.25267e-09 (rank : 19)	NC score	0.573853 (rank : 18)
Query Neighborhood Hits	206	Target Neighborhood Hits	115	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX6_HUMAN
θ value	1.38499e-08 (rank : 20)	NC score	0.567361 (rank : 20)
Query Neighborhood Hits	206	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	1.38499e-08 (rank : 21)	NC score	0.567196 (rank : 21)
Query Neighborhood Hits	206	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX52_HUMAN
θ value	5.81887e-07 (rank : 22)	NC score	0.564723 (rank : 24)
Query Neighborhood Hits	206	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX50_HUMAN
θ value	9.92553e-07 (rank : 23)	NC score	0.566219 (rank : 22)
Query Neighborhood Hits	206	Target Neighborhood Hits	132	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	9.92553e-07 (rank : 24)	NC score	0.565582 (rank : 23)
Query Neighborhood Hits	206	Target Neighborhood Hits	137	Shared Neighborhood Hits	84
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX52_MOUSE
θ value	9.92553e-07 (rank : 25)	NC score	0.561471 (rank : 25)
Query Neighborhood Hits	206	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX48_HUMAN
θ value	3.77169e-06 (rank : 26)	NC score	0.553388 (rank : 27)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	3.77169e-06 (rank : 27)	NC score	0.553164 (rank : 28)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

IF4A2_HUMAN
θ value	1.09739e-05 (rank : 28)	NC score	0.542314 (rank : 42)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	1.09739e-05 (rank : 29)	NC score	0.542314 (rank : 43)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX21_HUMAN
θ value	1.43324e-05 (rank : 30)	NC score	0.554525 (rank : 26)
Query Neighborhood Hits	206	Target Neighborhood Hits	308	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX21_MOUSE
θ value	2.44474e-05 (rank : 31)	NC score	0.547700 (rank : 34)
Query Neighborhood Hits	206	Target Neighborhood Hits	350	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX39_HUMAN
θ value	2.44474e-05 (rank : 32)	NC score	0.537952 (rank : 46)
Query Neighborhood Hits	206	Target Neighborhood Hits	94	Shared Neighborhood Hits	83
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
θ value	2.44474e-05 (rank : 33)	NC score	0.536935 (rank : 48)
Query Neighborhood Hits	206	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX27_MOUSE
θ value	3.19293e-05 (rank : 34)	NC score	0.537676 (rank : 47)
Query Neighborhood Hits	206	Target Neighborhood Hits	174	Shared Neighborhood Hits	83
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX3Y_HUMAN
θ value	3.19293e-05 (rank : 35)	NC score	0.551903 (rank : 30)
Query Neighborhood Hits	206	Target Neighborhood Hits	121	Shared Neighborhood Hits	83
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

IF4A1_HUMAN
θ value	3.19293e-05 (rank : 36)	NC score	0.540285 (rank : 44)
Query Neighborhood Hits	206	Target Neighborhood Hits	106	Shared Neighborhood Hits	83
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	3.19293e-05 (rank : 37)	NC score	0.540285 (rank : 45)
Query Neighborhood Hits	206	Target Neighborhood Hits	106	Shared Neighborhood Hits	83
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX3Y_MOUSE
θ value	5.44631e-05 (rank : 38)	NC score	0.547257 (rank : 35)
Query Neighborhood Hits	206	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX47_MOUSE
θ value	5.44631e-05 (rank : 39)	NC score	0.544432 (rank : 38)
Query Neighborhood Hits	206	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX27_HUMAN
θ value	7.1131e-05 (rank : 40)	NC score	0.536427 (rank : 49)
Query Neighborhood Hits	206	Target Neighborhood Hits	197	Shared Neighborhood Hits	85
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX3X_HUMAN
θ value	7.1131e-05 (rank : 41)	NC score	0.551270 (rank : 31)
Query Neighborhood Hits	206	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	7.1131e-05 (rank : 42)	NC score	0.552355 (rank : 29)
Query Neighborhood Hits	206	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

PL10_MOUSE
θ value	7.1131e-05 (rank : 43)	NC score	0.550338 (rank : 32)
Query Neighborhood Hits	206	Target Neighborhood Hits	120	Shared Neighborhood Hits	83
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX47_HUMAN
θ value	9.29e-05 (rank : 44)	NC score	0.544332 (rank : 39)
Query Neighborhood Hits	206	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

UAP56_HUMAN
θ value	0.000121331 (rank : 45)	NC score	0.530334 (rank : 50)
Query Neighborhood Hits	206	Target Neighborhood Hits	96	Shared Neighborhood Hits	83
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	0.000121331 (rank : 46)	NC score	0.530209 (rank : 51)
Query Neighborhood Hits	206	Target Neighborhood Hits	96	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX1_HUMAN
θ value	0.00020696 (rank : 47)	NC score	0.510608 (rank : 58)
Query Neighborhood Hits	206	Target Neighborhood Hits	110	Shared Neighborhood Hits	81
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	0.00020696 (rank : 48)	NC score	0.512733 (rank : 56)
Query Neighborhood Hits	206	Target Neighborhood Hits	112	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX23_HUMAN
θ value	0.000270298 (rank : 49)	NC score	0.544842 (rank : 37)
Query Neighborhood Hits	206	Target Neighborhood Hits	486	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX4_HUMAN
θ value	0.000270298 (rank : 50)	NC score	0.543324 (rank : 41)
Query Neighborhood Hits	206	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	0.000270298 (rank : 51)	NC score	0.544024 (rank : 40)
Query Neighborhood Hits	206	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX31_HUMAN
θ value	0.00035302 (rank : 52)	NC score	0.529839 (rank : 52)
Query Neighborhood Hits	206	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX49_HUMAN
θ value	0.000461057 (rank : 53)	NC score	0.547179 (rank : 36)
Query Neighborhood Hits	206	Target Neighborhood Hits	223	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX20_HUMAN
θ value	0.000602161 (rank : 54)	NC score	0.508283 (rank : 60)
Query Neighborhood Hits	206	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX49_MOUSE
θ value	0.000786445 (rank : 55)	NC score	0.548629 (rank : 33)
Query Neighborhood Hits	206	Target Neighborhood Hits	119	Shared Neighborhood Hits	86
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

HELC1_HUMAN
θ value	0.00102713 (rank : 56)	NC score	0.198850 (rank : 87)
Query Neighborhood Hits	206	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

DDX20_MOUSE
θ value	0.00134147 (rank : 57)	NC score	0.505195 (rank : 64)
Query Neighborhood Hits	206	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX28_MOUSE
θ value	0.00175202 (rank : 58)	NC score	0.515185 (rank : 55)
Query Neighborhood Hits	206	Target Neighborhood Hits	112	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX51_MOUSE
θ value	0.00390308 (rank : 59)	NC score	0.507481 (rank : 61)
Query Neighborhood Hits	206	Target Neighborhood Hits	130	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

LGP2_HUMAN
θ value	0.00390308 (rank : 60)	NC score	0.261077 (rank : 81)
Query Neighborhood Hits	206	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

DDX51_HUMAN
θ value	0.00509761 (rank : 61)	NC score	0.507098 (rank : 62)
Query Neighborhood Hits	206	Target Neighborhood Hits	332	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX25_HUMAN
θ value	0.00869519 (rank : 62)	NC score	0.490317 (rank : 67)
Query Neighborhood Hits	206	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
θ value	0.00869519 (rank : 63)	NC score	0.488240 (rank : 73)
Query Neighborhood Hits	206	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX54_HUMAN
θ value	0.00869519 (rank : 64)	NC score	0.517358 (rank : 54)
Query Neighborhood Hits	206	Target Neighborhood Hits	170	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX24_HUMAN
θ value	0.0113563 (rank : 65)	NC score	0.510439 (rank : 59)
Query Neighborhood Hits	206	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

LGP2_MOUSE
θ value	0.0113563 (rank : 66)	NC score	0.262085 (rank : 80)
Query Neighborhood Hits	206	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

SF01_HUMAN
θ value	0.0113563 (rank : 67)	NC score	0.068462 (rank : 97)
Query Neighborhood Hits	206	Target Neighborhood Hits	287	Shared Neighborhood Hits	24
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	0.0113563 (rank : 68)	NC score	0.070006 (rank : 96)
Query Neighborhood Hits	206	Target Neighborhood Hits	240	Shared Neighborhood Hits	20
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

U520_HUMAN
θ value	0.0113563 (rank : 69)	NC score	0.208678 (rank : 86)
Query Neighborhood Hits	206	Target Neighborhood Hits	88	Shared Neighborhood Hits	45
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CPSF4_HUMAN
θ value	0.0148317 (rank : 70)	NC score	0.072259 (rank : 95)
Query Neighborhood Hits	206	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

CPSF4_MOUSE
θ value	0.0148317 (rank : 71)	NC score	0.076529 (rank : 94)
Query Neighborhood Hits	206	Target Neighborhood Hits	58	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQZ5, O54930	Gene names	Cpsf4, Cpsf30
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K).

DD19A_HUMAN
θ value	0.0148317 (rank : 72)	NC score	0.488903 (rank : 69)
Query Neighborhood Hits	206	Target Neighborhood Hits	107	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	0.0148317 (rank : 73)	NC score	0.488240 (rank : 72)
Query Neighborhood Hits	206	Target Neighborhood Hits	105	Shared Neighborhood Hits	81
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	0.0148317 (rank : 74)	NC score	0.488565 (rank : 70)
Query Neighborhood Hits	206	Target Neighborhood Hits	109	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX18_MOUSE
θ value	0.0148317 (rank : 75)	NC score	0.488383 (rank : 71)
Query Neighborhood Hits	206	Target Neighborhood Hits	115	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX24_MOUSE
θ value	0.0148317 (rank : 76)	NC score	0.512215 (rank : 57)
Query Neighborhood Hits	206	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

KIF3C_MOUSE
θ value	0.0193708 (rank : 77)	NC score	0.018789 (rank : 146)
Query Neighborhood Hits	206	Target Neighborhood Hits	468	Shared Neighborhood Hits	10
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

TBX15_HUMAN
θ value	0.0252991 (rank : 78)	NC score	0.025065 (rank : 128)
Query Neighborhood Hits	206	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

BTBDC_HUMAN
θ value	0.0330416 (rank : 79)	NC score	0.060399 (rank : 99)
Query Neighborhood Hits	206	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

DDX10_MOUSE
θ value	0.0431538 (rank : 80)	NC score	0.504547 (rank : 65)
Query Neighborhood Hits	206	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX54_MOUSE
θ value	0.0736092 (rank : 81)	NC score	0.517541 (rank : 53)
Query Neighborhood Hits	206	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

ZO1_MOUSE
θ value	0.0736092 (rank : 82)	NC score	0.022216 (rank : 140)
Query Neighborhood Hits	206	Target Neighborhood Hits	453	Shared Neighborhood Hits	17
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

DDX10_HUMAN
θ value	0.0961366 (rank : 83)	NC score	0.506319 (rank : 63)
Query Neighborhood Hits	206	Target Neighborhood Hits	210	Shared Neighborhood Hits	86
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_HUMAN
θ value	0.0961366 (rank : 84)	NC score	0.490136 (rank : 68)
Query Neighborhood Hits	206	Target Neighborhood Hits	124	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX28_HUMAN
θ value	0.125558 (rank : 85)	NC score	0.495925 (rank : 66)
Query Neighborhood Hits	206	Target Neighborhood Hits	103	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

IFIH1_HUMAN
θ value	0.125558 (rank : 86)	NC score	0.250179 (rank : 82)
Query Neighborhood Hits	206	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
θ value	0.125558 (rank : 87)	NC score	0.243066 (rank : 83)
Query Neighborhood Hits	206	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX55_MOUSE
θ value	0.163984 (rank : 88)	NC score	0.486573 (rank : 74)
Query Neighborhood Hits	206	Target Neighborhood Hits	111	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DICER_MOUSE
θ value	0.163984 (rank : 89)	NC score	0.269246 (rank : 78)
Query Neighborhood Hits	206	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

MARCS_HUMAN
θ value	0.163984 (rank : 90)	NC score	0.046863 (rank : 103)
Query Neighborhood Hits	206	Target Neighborhood Hits	204	Shared Neighborhood Hits	9
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

DDX55_HUMAN
θ value	0.21417 (rank : 91)	NC score	0.485272 (rank : 75)
Query Neighborhood Hits	206	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX56_MOUSE
θ value	0.21417 (rank : 92)	NC score	0.472730 (rank : 76)
Query Neighborhood Hits	206	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DICER_HUMAN
θ value	0.21417 (rank : 93)	NC score	0.267102 (rank : 79)
Query Neighborhood Hits	206	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

KIF3C_HUMAN
θ value	0.21417 (rank : 94)	NC score	0.016254 (rank : 149)
Query Neighborhood Hits	206	Target Neighborhood Hits	478	Shared Neighborhood Hits	13
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

PTN13_HUMAN
θ value	0.21417 (rank : 95)	NC score	0.010439 (rank : 171)
Query Neighborhood Hits	206	Target Neighborhood Hits	471	Shared Neighborhood Hits	9
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

CALD1_HUMAN
θ value	0.279714 (rank : 96)	NC score	0.012965 (rank : 159)
Query Neighborhood Hits	206	Target Neighborhood Hits	959	Shared Neighborhood Hits	16
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

PACN1_HUMAN
θ value	0.279714 (rank : 97)	NC score	0.018493 (rank : 147)
Query Neighborhood Hits	206	Target Neighborhood Hits	320	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

YLPM1_HUMAN
θ value	0.279714 (rank : 98)	NC score	0.046458 (rank : 104)
Query Neighborhood Hits	206	Target Neighborhood Hits	670	Shared Neighborhood Hits	38
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ATBF1_HUMAN
θ value	0.365318 (rank : 99)	NC score	0.006858 (rank : 187)
Query Neighborhood Hits	206	Target Neighborhood Hits	1547	Shared Neighborhood Hits	16
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CQ028_HUMAN
θ value	0.365318 (rank : 100)	NC score	0.045057 (rank : 106)
Query Neighborhood Hits	206	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

SKIV2_HUMAN
θ value	0.365318 (rank : 101)	NC score	0.114891 (rank : 90)
Query Neighborhood Hits	206	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

CBP_HUMAN
θ value	0.47712 (rank : 102)	NC score	0.031022 (rank : 117)
Query Neighborhood Hits	206	Target Neighborhood Hits	941	Shared Neighborhood Hits	35
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DDX56_HUMAN
θ value	0.47712 (rank : 103)	NC score	0.470113 (rank : 77)
Query Neighborhood Hits	206	Target Neighborhood Hits	77	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

KCNB2_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.009895 (rank : 173)
Query Neighborhood Hits	206	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

CNBP_HUMAN
θ value	0.62314 (rank : 105)	NC score	0.049021 (rank : 102)
Query Neighborhood Hits	206	Target Neighborhood Hits	196	Shared Neighborhood Hits	24
SwissProt Accessions	P62633, P20694, Q5QJR0, Q6PJI7, Q96NV3	Gene names	CNBP, ZNF9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

CQ028_MOUSE
θ value	0.62314 (rank : 106)	NC score	0.043148 (rank : 108)
Query Neighborhood Hits	206	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

DUS16_HUMAN
θ value	0.62314 (rank : 107)	NC score	0.013827 (rank : 156)
Query Neighborhood Hits	206	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

MADCA_HUMAN
θ value	0.62314 (rank : 108)	NC score	0.031860 (rank : 112)
Query Neighborhood Hits	206	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

PHLPL_MOUSE
θ value	0.62314 (rank : 109)	NC score	0.008030 (rank : 181)
Query Neighborhood Hits	206	Target Neighborhood Hits	303	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

RBM4B_HUMAN
θ value	0.62314 (rank : 110)	NC score	0.031279 (rank : 115)
Query Neighborhood Hits	206	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQ04	Gene names	RBM4B, RBM30
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4B (RNA-binding motif protein 4B) (RNA-binding protein 30) (RNA-binding motif protein 30).

RBM4B_MOUSE
θ value	0.62314 (rank : 111)	NC score	0.031248 (rank : 116)
Query Neighborhood Hits	206	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VE92	Gene names	Rbm4b, Rbm30
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4B (RNA-binding motif protein 4B) (RNA-binding protein 30) (RNA-binding motif protein 30).

RBM4_HUMAN
θ value	0.62314 (rank : 112)	NC score	0.031731 (rank : 113)
Query Neighborhood Hits	206	Target Neighborhood Hits	219	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWF3, O02916, Q6P1P2, Q8WU85	Gene names	RBM4, RBM4A
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (hLark).

RBM4_MOUSE
θ value	0.62314 (rank : 113)	NC score	0.031665 (rank : 114)
Query Neighborhood Hits	206	Target Neighborhood Hits	223	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C7Q4, O08752, Q8BN66	Gene names	Rbm4, Rbm4a
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (mLark).

BSN_MOUSE
θ value	0.813845 (rank : 114)	NC score	0.026818 (rank : 122)
Query Neighborhood Hits	206	Target Neighborhood Hits	2057	Shared Neighborhood Hits	59
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MK04_HUMAN
θ value	0.813845 (rank : 115)	NC score	-0.002234 (rank : 212)
Query Neighborhood Hits	206	Target Neighborhood Hits	837	Shared Neighborhood Hits	5
SwissProt Accessions	P31152	Gene names	MAPK4, ERK4, PRKM4
Domain Architecture
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63- MAPK).

ACD_HUMAN
θ value	1.06291 (rank : 116)	NC score	0.032756 (rank : 111)
Query Neighborhood Hits	206	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

GCC2_MOUSE
θ value	1.06291 (rank : 117)	NC score	0.006980 (rank : 184)
Query Neighborhood Hits	206	Target Neighborhood Hits	1619	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MYBPH_MOUSE
θ value	1.06291 (rank : 118)	NC score	0.011214 (rank : 165)
Query Neighborhood Hits	206	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

PRG4_HUMAN
θ value	1.06291 (rank : 119)	NC score	0.014989 (rank : 152)
Query Neighborhood Hits	206	Target Neighborhood Hits	764	Shared Neighborhood Hits	28
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SACS_HUMAN
θ value	1.06291 (rank : 120)	NC score	0.020161 (rank : 142)
Query Neighborhood Hits	206	Target Neighborhood Hits	128	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

BPA1_MOUSE
θ value	1.38821 (rank : 121)	NC score	0.006510 (rank : 189)
Query Neighborhood Hits	206	Target Neighborhood Hits	1477	Shared Neighborhood Hits	27
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CABP4_HUMAN
θ value	1.38821 (rank : 122)	NC score	0.010145 (rank : 172)
Query Neighborhood Hits	206	Target Neighborhood Hits	250	Shared Neighborhood Hits	6
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CAF1B_MOUSE
θ value	1.38821 (rank : 123)	NC score	0.008165 (rank : 179)
Query Neighborhood Hits	206	Target Neighborhood Hits	385	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CJ012_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.028451 (rank : 120)
Query Neighborhood Hits	206	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CNBP_MOUSE
θ value	1.38821 (rank : 125)	NC score	0.044752 (rank : 107)
Query Neighborhood Hits	206	Target Neighborhood Hits	215	Shared Neighborhood Hits	24
SwissProt Accessions	P53996, Q80Y06, Q8BP23	Gene names	Cnbp, Cnbp1, Znf9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

GFC1_HUMAN
θ value	1.38821 (rank : 126)	NC score	0.028898 (rank : 118)
Query Neighborhood Hits	206	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

HV2I_HUMAN
θ value	1.38821 (rank : 127)	NC score	0.004415 (rank : 197)
Query Neighborhood Hits	206	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	P06331	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-II region ARH-77 precursor.

MARCS_MOUSE
θ value	1.38821 (rank : 128)	NC score	0.045551 (rank : 105)
Query Neighborhood Hits	206	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

PELP1_HUMAN
θ value	1.38821 (rank : 129)	NC score	0.024430 (rank : 135)
Query Neighborhood Hits	206	Target Neighborhood Hits	596	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

SK2L2_HUMAN
θ value	1.38821 (rank : 130)	NC score	0.097110 (rank : 91)
Query Neighborhood Hits	206	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
θ value	1.38821 (rank : 131)	NC score	0.095831 (rank : 92)
Query Neighborhood Hits	206	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SPG20_MOUSE
θ value	1.38821 (rank : 132)	NC score	0.023790 (rank : 137)
Query Neighborhood Hits	206	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1X6, Q6ZQ87, Q8BJD3, Q8BM37, Q8BZ63	Gene names	Spg20, Kiaa0610
Domain Architecture	No domain graphic available
Description	Spartin.

TBX15_MOUSE
θ value	1.38821 (rank : 133)	NC score	0.018478 (rank : 148)
Query Neighborhood Hits	206	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

ZCHC6_HUMAN
θ value	1.38821 (rank : 134)	NC score	0.026105 (rank : 123)
Query Neighborhood Hits	206	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

BSN_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.028693 (rank : 119)
Query Neighborhood Hits	206	Target Neighborhood Hits	1537	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CNOT3_MOUSE
θ value	1.81305 (rank : 136)	NC score	0.021200 (rank : 141)
Query Neighborhood Hits	206	Target Neighborhood Hits	504	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

LMBL3_MOUSE
θ value	1.81305 (rank : 137)	NC score	0.014415 (rank : 153)
Query Neighborhood Hits	206	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

LY75_MOUSE
θ value	1.81305 (rank : 138)	NC score	0.009809 (rank : 174)
Query Neighborhood Hits	206	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

MAP4_MOUSE
θ value	1.81305 (rank : 139)	NC score	0.025953 (rank : 124)
Query Neighborhood Hits	206	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

AFF1_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.013971 (rank : 155)
Query Neighborhood Hits	206	Target Neighborhood Hits	506	Shared Neighborhood Hits	16
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BRAP_MOUSE
θ value	2.36792 (rank : 141)	NC score	0.015619 (rank : 150)
Query Neighborhood Hits	206	Target Neighborhood Hits	409	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CF125_HUMAN
θ value	2.36792 (rank : 142)	NC score	0.027464 (rank : 121)
Query Neighborhood Hits	206	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRT2	Gene names	C6orf125
Domain Architecture	No domain graphic available
Description	Protein C6orf125 (Breast cancer-associated protein SGA-81M).

CNR2_MOUSE
θ value	2.36792 (rank : 143)	NC score	-0.000054 (rank : 210)
Query Neighborhood Hits	206	Target Neighborhood Hits	738	Shared Neighborhood Hits	2
SwissProt Accessions	P47936	Gene names	Cnr2
Domain Architecture
Description	Cannabinoid receptor 2 (CB2) (CB-2).

K0323_HUMAN
θ value	2.36792 (rank : 144)	NC score	0.025578 (rank : 125)
Query Neighborhood Hits	206	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

MITF_MOUSE
θ value	2.36792 (rank : 145)	NC score	0.013807 (rank : 157)
Query Neighborhood Hits	206	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

BNC2_MOUSE
θ value	3.0926 (rank : 146)	NC score	0.010565 (rank : 170)
Query Neighborhood Hits	206	Target Neighborhood Hits	456	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

CE005_HUMAN
θ value	3.0926 (rank : 147)	NC score	0.010871 (rank : 167)
Query Neighborhood Hits	206	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

HCN3_HUMAN
θ value	3.0926 (rank : 148)	NC score	0.006893 (rank : 186)
Query Neighborhood Hits	206	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

ICAL_HUMAN
θ value	3.0926 (rank : 149)	NC score	0.022423 (rank : 139)
Query Neighborhood Hits	206	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

SETB1_MOUSE
θ value	3.0926 (rank : 150)	NC score	0.012453 (rank : 161)
Query Neighborhood Hits	206	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

FBX34_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.013262 (rank : 158)
Query Neighborhood Hits	206	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

GAK10_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.024889 (rank : 132)
Query Neighborhood Hits	206	Target Neighborhood Hits	289	Shared Neighborhood Hits	32
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

INVS_MOUSE
θ value	4.03905 (rank : 153)	NC score	0.003324 (rank : 203)
Query Neighborhood Hits	206	Target Neighborhood Hits	609	Shared Neighborhood Hits	22
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

KCNN3_HUMAN
θ value	4.03905 (rank : 154)	NC score	0.008754 (rank : 177)
Query Neighborhood Hits	206	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

MLTK_HUMAN
θ value	4.03905 (rank : 155)	NC score	-0.004829 (rank : 214)
Query Neighborhood Hits	206	Target Neighborhood Hits	911	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

NCA11_MOUSE
θ value	4.03905 (rank : 156)	NC score	0.002289 (rank : 205)
Query Neighborhood Hits	206	Target Neighborhood Hits	661	Shared Neighborhood Hits	14
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

SEZ6L_HUMAN
θ value	4.03905 (rank : 157)	NC score	0.007277 (rank : 183)
Query Neighborhood Hits	206	Target Neighborhood Hits	289	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SPEG_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.001004 (rank : 208)
Query Neighborhood Hits	206	Target Neighborhood Hits	1959	Shared Neighborhood Hits	48
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TLN1_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.012123 (rank : 162)
Query Neighborhood Hits	206	Target Neighborhood Hits	218	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

WBS14_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.015364 (rank : 151)
Query Neighborhood Hits	206	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

B4GN1_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.011089 (rank : 166)
Query Neighborhood Hits	206	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q00973	Gene names	B4GALNT1, GALGT, SIAT2
Domain Architecture
Description	Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N- acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T).

BAI1_HUMAN
θ value	5.27518 (rank : 162)	NC score	0.002065 (rank : 206)
Query Neighborhood Hits	206	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CBP_MOUSE
θ value	5.27518 (rank : 163)	NC score	0.025025 (rank : 130)
Query Neighborhood Hits	206	Target Neighborhood Hits	1051	Shared Neighborhood Hits	34
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

COIA1_MOUSE
θ value	5.27518 (rank : 164)	NC score	0.005416 (rank : 192)
Query Neighborhood Hits	206	Target Neighborhood Hits	481	Shared Neighborhood Hits	16
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GAK11_HUMAN
θ value	5.27518 (rank : 165)	NC score	0.024911 (rank : 131)
Query Neighborhood Hits	206	Target Neighborhood Hits	409	Shared Neighborhood Hits	34
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.024663 (rank : 134)
Query Neighborhood Hits	206	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	5.27518 (rank : 167)	NC score	0.025193 (rank : 126)
Query Neighborhood Hits	206	Target Neighborhood Hits	406	Shared Neighborhood Hits	35
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	5.27518 (rank : 168)	NC score	0.025117 (rank : 127)
Query Neighborhood Hits	206	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.025026 (rank : 129)
Query Neighborhood Hits	206	Target Neighborhood Hits	429	Shared Neighborhood Hits	36
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NFH_MOUSE
θ value	5.27518 (rank : 170)	NC score	0.010866 (rank : 168)
Query Neighborhood Hits	206	Target Neighborhood Hits	2247	Shared Neighborhood Hits	55
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PAD5_MOUSE
θ value	5.27518 (rank : 171)	NC score	0.012460 (rank : 160)
Query Neighborhood Hits	206	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q68ED3, Q8C0K6	Gene names	Papd5
Domain Architecture	No domain graphic available
Description	PAP-associated domain-containing protein 5 (EC 2.7.7.-) (Topoisomerase-related function protein 4-2) (TRF4-2).

PDE1C_MOUSE
θ value	5.27518 (rank : 172)	NC score	0.004250 (rank : 198)
Query Neighborhood Hits	206	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

PGCA_MOUSE
θ value	5.27518 (rank : 173)	NC score	0.003339 (rank : 202)
Query Neighborhood Hits	206	Target Neighborhood Hits	643	Shared Neighborhood Hits	11
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PRR13_MOUSE
θ value	5.27518 (rank : 174)	NC score	0.034838 (rank : 109)
Query Neighborhood Hits	206	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

REST_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.003409 (rank : 201)
Query Neighborhood Hits	206	Target Neighborhood Hits	1506	Shared Neighborhood Hits	34
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ANKS1_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.000167 (rank : 209)
Query Neighborhood Hits	206	Target Neighborhood Hits	438	Shared Neighborhood Hits	6
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

CCD96_HUMAN
θ value	6.88961 (rank : 177)	NC score	0.008655 (rank : 178)
Query Neighborhood Hits	206	Target Neighborhood Hits	595	Shared Neighborhood Hits	22
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CE005_MOUSE
θ value	6.88961 (rank : 178)	NC score	0.009710 (rank : 175)
Query Neighborhood Hits	206	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

EP300_HUMAN
θ value	6.88961 (rank : 179)	NC score	0.019450 (rank : 144)
Query Neighborhood Hits	206	Target Neighborhood Hits	821	Shared Neighborhood Hits	28
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GAK3_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.023549 (rank : 138)
Query Neighborhood Hits	206	Target Neighborhood Hits	182	Shared Neighborhood Hits	24
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GRAP1_HUMAN
θ value	6.88961 (rank : 181)	NC score	0.003964 (rank : 200)
Query Neighborhood Hits	206	Target Neighborhood Hits	944	Shared Neighborhood Hits	18
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

INADL_MOUSE
θ value	6.88961 (rank : 182)	NC score	0.006940 (rank : 185)
Query Neighborhood Hits	206	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

NUCKS_MOUSE
θ value	6.88961 (rank : 183)	NC score	0.014133 (rank : 154)
Query Neighborhood Hits	206	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

PACN1_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.011482 (rank : 164)
Query Neighborhood Hits	206	Target Neighborhood Hits	283	Shared Neighborhood Hits	5
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PRDM2_HUMAN
θ value	6.88961 (rank : 185)	NC score	-0.001899 (rank : 211)
Query Neighborhood Hits	206	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

REST_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.003291 (rank : 204)
Query Neighborhood Hits	206	Target Neighborhood Hits	1605	Shared Neighborhood Hits	30
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ZCH13_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.033191 (rank : 110)
Query Neighborhood Hits	206	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WW36	Gene names	ZCCHC13
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 13.

ZCH14_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.019013 (rank : 145)
Query Neighborhood Hits	206	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZCH14_MOUSE
θ value	6.88961 (rank : 189)	NC score	0.019689 (rank : 143)
Query Neighborhood Hits	206	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

BCOR_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.001628 (rank : 207)
Query Neighborhood Hits	206	Target Neighborhood Hits	521	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BRAP_HUMAN
θ value	8.99809 (rank : 191)	NC score	0.008908 (rank : 176)
Query Neighborhood Hits	206	Target Neighborhood Hits	560	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

EP400_MOUSE
θ value	8.99809 (rank : 192)	NC score	0.004859 (rank : 195)
Query Neighborhood Hits	206	Target Neighborhood Hits	592	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EVPL_HUMAN
θ value	8.99809 (rank : 193)	NC score	0.006814 (rank : 188)
Query Neighborhood Hits	206	Target Neighborhood Hits	895	Shared Neighborhood Hits	20
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EVPL_MOUSE
θ value	8.99809 (rank : 194)	NC score	0.004997 (rank : 194)
Query Neighborhood Hits	206	Target Neighborhood Hits	952	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

F5006_HUMAN
θ value	8.99809 (rank : 195)	NC score	-0.004439 (rank : 213)
Query Neighborhood Hits	206	Target Neighborhood Hits	794	Shared Neighborhood Hits	5
SwissProt Accessions	Q96LW2, Q49A48	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

GAK12_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.024819 (rank : 133)
Query Neighborhood Hits	206	Target Neighborhood Hits	374	Shared Neighborhood Hits	35
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.024180 (rank : 136)
Query Neighborhood Hits	206	Target Neighborhood Hits	392	Shared Neighborhood Hits	36
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GRAP1_MOUSE
θ value	8.99809 (rank : 198)	NC score	0.006048 (rank : 190)
Query Neighborhood Hits	206	Target Neighborhood Hits	1234	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

IASPP_MOUSE
θ value	8.99809 (rank : 199)	NC score	0.004567 (rank : 196)
Query Neighborhood Hits	206	Target Neighborhood Hits	1024	Shared Neighborhood Hits	33
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MKL1_MOUSE
θ value	8.99809 (rank : 200)	NC score	0.008098 (rank : 180)
Query Neighborhood Hits	206	Target Neighborhood Hits	667	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NCF1_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.003976 (rank : 199)
Query Neighborhood Hits	206	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

PTC1_HUMAN
θ value	8.99809 (rank : 202)	NC score	0.005563 (rank : 191)
Query Neighborhood Hits	206	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

PTPRN_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.005189 (rank : 193)
Query Neighborhood Hits	206	Target Neighborhood Hits	240	Shared Neighborhood Hits	14
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RIMB1_HUMAN
θ value	8.99809 (rank : 204)	NC score	0.007925 (rank : 182)
Query Neighborhood Hits	206	Target Neighborhood Hits	1479	Shared Neighborhood Hits	41
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SENP6_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.011593 (rank : 163)
Query Neighborhood Hits	206	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

TLN1_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.010747 (rank : 169)
Query Neighborhood Hits	206	Target Neighborhood Hits	213	Shared Neighborhood Hits	11
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

CC026_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.089414 (rank : 93)
Query Neighborhood Hits	206	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.060852 (rank : 98)
Query Neighborhood Hits	206	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

DDX58_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.130287 (rank : 89)
Query Neighborhood Hits	206	Target Neighborhood Hits	105	Shared Neighborhood Hits	54
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.146150 (rank : 88)
Query Neighborhood Hits	206	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

EXDL2_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.056129 (rank : 100)
Query Neighborhood Hits	206	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.054383 (rank : 101)
Query Neighborhood Hits	206	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

FANCM_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.238917 (rank : 84)
Query Neighborhood Hits	206	Target Neighborhood Hits	210	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.236610 (rank : 85)
Query Neighborhood Hits	206	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

Hits sorted by NC score

RECQ4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	206	Target Neighborhood Hits	206	Shared Neighborhood Hits	206
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RECQ4_HUMAN
NC score	0.966352 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	206	Target Neighborhood Hits	177	Shared Neighborhood Hits	94
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ1_MOUSE
NC score	0.828771 (rank : 3)	θ value	7.27602e-42 (rank : 7)
Query Neighborhood Hits	206	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_HUMAN
NC score	0.827957 (rank : 4)	θ value	5.57106e-42 (rank : 6)
Query Neighborhood Hits	206	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

BLM_MOUSE
NC score	0.817452 (rank : 5)	θ value	8.59492e-43 (rank : 5)
Query Neighborhood Hits	206	Target Neighborhood Hits	108	Shared Neighborhood Hits	73
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.811873 (rank : 6)	θ value	8.59492e-43 (rank : 4)
Query Neighborhood Hits	206	Target Neighborhood Hits	148	Shared Neighborhood Hits	75
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
NC score	0.803849 (rank : 7)	θ value	2.04573e-44 (rank : 3)
Query Neighborhood Hits	206	Target Neighborhood Hits	390	Shared Neighborhood Hits	86
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_HUMAN
NC score	0.799419 (rank : 8)	θ value	5.21438e-40 (rank : 8)
Query Neighborhood Hits	206	Target Neighborhood Hits	132	Shared Neighborhood Hits	83
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
NC score	0.783924 (rank : 9)	θ value	4.88048e-38 (rank : 9)
Query Neighborhood Hits	206	Target Neighborhood Hits	295	Shared Neighborhood Hits	84
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DDX5_MOUSE
NC score	0.603865 (rank : 10)	θ value	6.85773e-16 (rank : 11)
Query Neighborhood Hits	206	Target Neighborhood Hits	101	Shared Neighborhood Hits	83
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.603817 (rank : 11)	θ value	3.07829e-16 (rank : 10)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX17_MOUSE
NC score	0.601594 (rank : 12)	θ value	1.42992e-13 (rank : 14)
Query Neighborhood Hits	206	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.601538 (rank : 13)	θ value	1.42992e-13 (rank : 13)
Query Neighborhood Hits	206	Target Neighborhood Hits	104	Shared Neighborhood Hits	83
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX43_HUMAN
NC score	0.594850 (rank : 14)	θ value	5.8054e-15 (rank : 12)
Query Neighborhood Hits	206	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX46_HUMAN
NC score	0.588694 (rank : 15)	θ value	4.16044e-13 (rank : 15)
Query Neighborhood Hits	206	Target Neighborhood Hits	357	Shared Neighborhood Hits	90
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
NC score	0.587719 (rank : 16)	θ value	4.16044e-13 (rank : 16)
Query Neighborhood Hits	206	Target Neighborhood Hits	358	Shared Neighborhood Hits	91
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX41_HUMAN
NC score	0.575999 (rank : 17)	θ value	7.34386e-10 (rank : 18)
Query Neighborhood Hits	206	Target Neighborhood Hits	111	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.573853 (rank : 18)	θ value	1.25267e-09 (rank : 19)
Query Neighborhood Hits	206	Target Neighborhood Hits	115	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX53_HUMAN
NC score	0.567976 (rank : 19)	θ value	3.29651e-10 (rank : 17)
Query Neighborhood Hits	206	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX6_HUMAN
NC score	0.567361 (rank : 20)	θ value	1.38499e-08 (rank : 20)
Query Neighborhood Hits	206	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.567196 (rank : 21)	θ value	1.38499e-08 (rank : 21)
Query Neighborhood Hits	206	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX50_HUMAN
NC score	0.566219 (rank : 22)	θ value	9.92553e-07 (rank : 23)
Query Neighborhood Hits	206	Target Neighborhood Hits	132	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.565582 (rank : 23)	θ value	9.92553e-07 (rank : 24)
Query Neighborhood Hits	206	Target Neighborhood Hits	137	Shared Neighborhood Hits	84
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX52_HUMAN
NC score	0.564723 (rank : 24)	θ value	5.81887e-07 (rank : 22)
Query Neighborhood Hits	206	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
NC score	0.561471 (rank : 25)	θ value	9.92553e-07 (rank : 25)
Query Neighborhood Hits	206	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX21_HUMAN
NC score	0.554525 (rank : 26)	θ value	1.43324e-05 (rank : 30)
Query Neighborhood Hits	206	Target Neighborhood Hits	308	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX48_HUMAN
NC score	0.553388 (rank : 27)	θ value	3.77169e-06 (rank : 26)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.553164 (rank : 28)	θ value	3.77169e-06 (rank : 27)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX3X_MOUSE
NC score	0.552355 (rank : 29)	θ value	7.1131e-05 (rank : 42)
Query Neighborhood Hits	206	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
NC score	0.551903 (rank : 30)	θ value	3.19293e-05 (rank : 35)
Query Neighborhood Hits	206	Target Neighborhood Hits	121	Shared Neighborhood Hits	83
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX3X_HUMAN
NC score	0.551270 (rank : 31)	θ value	7.1131e-05 (rank : 41)
Query Neighborhood Hits	206	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

PL10_MOUSE
NC score	0.550338 (rank : 32)	θ value	7.1131e-05 (rank : 43)
Query Neighborhood Hits	206	Target Neighborhood Hits	120	Shared Neighborhood Hits	83
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX49_MOUSE
NC score	0.548629 (rank : 33)	θ value	0.000786445 (rank : 55)
Query Neighborhood Hits	206	Target Neighborhood Hits	119	Shared Neighborhood Hits	86
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX21_MOUSE
NC score	0.547700 (rank : 34)	θ value	2.44474e-05 (rank : 31)
Query Neighborhood Hits	206	Target Neighborhood Hits	350	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX3Y_MOUSE
NC score	0.547257 (rank : 35)	θ value	5.44631e-05 (rank : 38)
Query Neighborhood Hits	206	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX49_HUMAN
NC score	0.547179 (rank : 36)	θ value	0.000461057 (rank : 53)
Query Neighborhood Hits	206	Target Neighborhood Hits	223	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX23_HUMAN
NC score	0.544842 (rank : 37)	θ value	0.000270298 (rank : 49)
Query Neighborhood Hits	206	Target Neighborhood Hits	486	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX47_MOUSE
NC score	0.544432 (rank : 38)	θ value	5.44631e-05 (rank : 39)
Query Neighborhood Hits	206	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.544332 (rank : 39)	θ value	9.29e-05 (rank : 44)
Query Neighborhood Hits	206	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX4_MOUSE
NC score	0.544024 (rank : 40)	θ value	0.000270298 (rank : 51)
Query Neighborhood Hits	206	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX4_HUMAN
NC score	0.543324 (rank : 41)	θ value	0.000270298 (rank : 50)
Query Neighborhood Hits	206	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

IF4A2_HUMAN
NC score	0.542314 (rank : 42)	θ value	1.09739e-05 (rank : 28)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.542314 (rank : 43)	θ value	1.09739e-05 (rank : 29)
Query Neighborhood Hits	206	Target Neighborhood Hits	102	Shared Neighborhood Hits	83
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A1_HUMAN
NC score	0.540285 (rank : 44)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	206	Target Neighborhood Hits	106	Shared Neighborhood Hits	83
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.540285 (rank : 45)	θ value	3.19293e-05 (rank : 37)
Query Neighborhood Hits	206	Target Neighborhood Hits	106	Shared Neighborhood Hits	83
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX39_HUMAN
NC score	0.537952 (rank : 46)	θ value	2.44474e-05 (rank : 32)
Query Neighborhood Hits	206	Target Neighborhood Hits	94	Shared Neighborhood Hits	83
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX27_MOUSE
NC score	0.537676 (rank : 47)	θ value	3.19293e-05 (rank : 34)
Query Neighborhood Hits	206	Target Neighborhood Hits	174	Shared Neighborhood Hits	83
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX39_MOUSE
NC score	0.536935 (rank : 48)	θ value	2.44474e-05 (rank : 33)
Query Neighborhood Hits	206	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX27_HUMAN
NC score	0.536427 (rank : 49)	θ value	7.1131e-05 (rank : 40)
Query Neighborhood Hits	206	Target Neighborhood Hits	197	Shared Neighborhood Hits	85
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

UAP56_HUMAN
NC score	0.530334 (rank : 50)	θ value	0.000121331 (rank : 45)
Query Neighborhood Hits	206	Target Neighborhood Hits	96	Shared Neighborhood Hits	83
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.530209 (rank : 51)	θ value	0.000121331 (rank : 46)
Query Neighborhood Hits	206	Target Neighborhood Hits	96	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX31_HUMAN
NC score	0.529839 (rank : 52)	θ value	0.00035302 (rank : 52)
Query Neighborhood Hits	206	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX54_MOUSE
NC score	0.517541 (rank : 53)	θ value	0.0736092 (rank : 81)
Query Neighborhood Hits	206	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX54_HUMAN
NC score	0.517358 (rank : 54)	θ value	0.00869519 (rank : 64)
Query Neighborhood Hits	206	Target Neighborhood Hits	170	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX28_MOUSE
NC score	0.515185 (rank : 55)	θ value	0.00175202 (rank : 58)
Query Neighborhood Hits	206	Target Neighborhood Hits	112	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX1_MOUSE
NC score	0.512733 (rank : 56)	θ value	0.00020696 (rank : 48)
Query Neighborhood Hits	206	Target Neighborhood Hits	112	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX24_MOUSE
NC score	0.512215 (rank : 57)	θ value	0.0148317 (rank : 76)
Query Neighborhood Hits	206	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX1_HUMAN
NC score	0.510608 (rank : 58)	θ value	0.00020696 (rank : 47)
Query Neighborhood Hits	206	Target Neighborhood Hits	110	Shared Neighborhood Hits	81
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX24_HUMAN
NC score	0.510439 (rank : 59)	θ value	0.0113563 (rank : 65)
Query Neighborhood Hits	206	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX20_HUMAN
NC score	0.508283 (rank : 60)	θ value	0.000602161 (rank : 54)
Query Neighborhood Hits	206	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX51_MOUSE
NC score	0.507481 (rank : 61)	θ value	0.00390308 (rank : 59)
Query Neighborhood Hits	206	Target Neighborhood Hits	130	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_HUMAN
NC score	0.507098 (rank : 62)	θ value	0.00509761 (rank : 61)
Query Neighborhood Hits	206	Target Neighborhood Hits	332	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX10_HUMAN
NC score	0.506319 (rank : 63)	θ value	0.0961366 (rank : 83)
Query Neighborhood Hits	206	Target Neighborhood Hits	210	Shared Neighborhood Hits	86
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX20_MOUSE
NC score	0.505195 (rank : 64)	θ value	0.00134147 (rank : 57)
Query Neighborhood Hits	206	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX10_MOUSE
NC score	0.504547 (rank : 65)	θ value	0.0431538 (rank : 80)
Query Neighborhood Hits	206	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX28_HUMAN
NC score	0.495925 (rank : 66)	θ value	0.125558 (rank : 85)
Query Neighborhood Hits	206	Target Neighborhood Hits	103	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX25_HUMAN
NC score	0.490317 (rank : 67)	θ value	0.00869519 (rank : 62)
Query Neighborhood Hits	206	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX18_HUMAN
NC score	0.490136 (rank : 68)	θ value	0.0961366 (rank : 84)
Query Neighborhood Hits	206	Target Neighborhood Hits	124	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DD19A_HUMAN
NC score	0.488903 (rank : 69)	θ value	0.0148317 (rank : 72)
Query Neighborhood Hits	206	Target Neighborhood Hits	107	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.488565 (rank : 70)	θ value	0.0148317 (rank : 74)
Query Neighborhood Hits	206	Target Neighborhood Hits	109	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX18_MOUSE
NC score	0.488383 (rank : 71)	θ value	0.0148317 (rank : 75)
Query Neighborhood Hits	206	Target Neighborhood Hits	115	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DD19A_MOUSE
NC score	0.488240 (rank : 72)	θ value	0.0148317 (rank : 73)
Query Neighborhood Hits	206	Target Neighborhood Hits	105	Shared Neighborhood Hits	81
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX25_MOUSE
NC score	0.488240 (rank : 73)	θ value	0.00869519 (rank : 63)
Query Neighborhood Hits	206	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX55_MOUSE
NC score	0.486573 (rank : 74)	θ value	0.163984 (rank : 88)
Query Neighborhood Hits	206	Target Neighborhood Hits	111	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
NC score	0.485272 (rank : 75)	θ value	0.21417 (rank : 91)
Query Neighborhood Hits	206	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX56_MOUSE
NC score	0.472730 (rank : 76)	θ value	0.21417 (rank : 92)
Query Neighborhood Hits	206	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
NC score	0.470113 (rank : 77)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	206	Target Neighborhood Hits	77	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DICER_MOUSE
NC score	0.269246 (rank : 78)	θ value	0.163984 (rank : 89)
Query Neighborhood Hits	206	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
NC score	0.267102 (rank : 79)	θ value	0.21417 (rank : 93)
Query Neighborhood Hits	206	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

LGP2_MOUSE
NC score	0.262085 (rank : 80)	θ value	0.0113563 (rank : 66)
Query Neighborhood Hits	206	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

LGP2_HUMAN
NC score	0.261077 (rank : 81)	θ value	0.00390308 (rank : 60)
Query Neighborhood Hits	206	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_HUMAN
NC score	0.250179 (rank : 82)	θ value	0.125558 (rank : 86)
Query Neighborhood Hits	206	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
NC score	0.243066 (rank : 83)	θ value	0.125558 (rank : 87)
Query Neighborhood Hits	206	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

FANCM_HUMAN
NC score	0.238917 (rank : 84)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	206	Target Neighborhood Hits	210	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.236610 (rank : 85)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	206	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

U520_HUMAN
NC score	0.208678 (rank : 86)	θ value	0.0113563 (rank : 69)
Query Neighborhood Hits	206	Target Neighborhood Hits	88	Shared Neighborhood Hits	45
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

HELC1_HUMAN
NC score	0.198850 (rank : 87)	θ value	0.00102713 (rank : 56)
Query Neighborhood Hits	206	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

DDX58_MOUSE
NC score	0.146150 (rank : 88)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	206	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.130287 (rank : 89)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	206	Target Neighborhood Hits	105	Shared Neighborhood Hits	54
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

SKIV2_HUMAN
NC score	0.114891 (rank : 90)	θ value	0.365318 (rank : 101)
Query Neighborhood Hits	206	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

SK2L2_HUMAN
NC score	0.097110 (rank : 91)	θ value	1.38821 (rank : 130)
Query Neighborhood Hits	206	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
NC score	0.095831 (rank : 92)	θ value	1.38821 (rank : 131)
Query Neighborhood Hits	206	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

CC026_HUMAN
NC score	0.089414 (rank : 93)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	206	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CPSF4_MOUSE
NC score	0.076529 (rank : 94)	θ value	0.0148317 (rank : 71)
Query Neighborhood Hits	206	Target Neighborhood Hits	58	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQZ5, O54930	Gene names	Cpsf4, Cpsf30
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K).

CPSF4_HUMAN
NC score	0.072259 (rank : 95)	θ value	0.0148317 (rank : 70)
Query Neighborhood Hits	206	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

SF01_MOUSE
NC score	0.070006 (rank : 96)	θ value	0.0113563 (rank : 68)
Query Neighborhood Hits	206	Target Neighborhood Hits	240	Shared Neighborhood Hits	20
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF01_HUMAN
NC score	0.068462 (rank : 97)	θ value	0.0113563 (rank : 67)
Query Neighborhood Hits	206	Target Neighborhood Hits	287	Shared Neighborhood Hits	24
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

CC026_MOUSE
NC score	0.060852 (rank : 98)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	206	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

BTBDC_HUMAN
NC score	0.060399 (rank : 99)	θ value	0.0330416 (rank : 79)
Query Neighborhood Hits	206	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

EXDL2_HUMAN
NC score	0.056129 (rank : 100)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	206	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
NC score	0.054383 (rank : 101)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	206	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

CNBP_HUMAN
NC score	0.049021 (rank : 102)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	206	Target Neighborhood Hits	196	Shared Neighborhood Hits	24
SwissProt Accessions	P62633, P20694, Q5QJR0, Q6PJI7, Q96NV3	Gene names	CNBP, ZNF9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

MARCS_HUMAN
NC score	0.046863 (rank : 103)	θ value	0.163984 (rank : 90)
Query Neighborhood Hits	206	Target Neighborhood Hits	204	Shared Neighborhood Hits	9
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

YLPM1_HUMAN
NC score	0.046458 (rank : 104)	θ value	0.279714 (rank : 98)
Query Neighborhood Hits	206	Target Neighborhood Hits	670	Shared Neighborhood Hits	38
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

MARCS_MOUSE
NC score	0.045551 (rank : 105)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	206	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

CQ028_HUMAN
NC score	0.045057 (rank : 106)	θ value	0.365318 (rank : 100)
Query Neighborhood Hits	206	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

CNBP_MOUSE
NC score	0.044752 (rank : 107)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	206	Target Neighborhood Hits	215	Shared Neighborhood Hits	24
SwissProt Accessions	P53996, Q80Y06, Q8BP23	Gene names	Cnbp, Cnbp1, Znf9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

CQ028_MOUSE
NC score	0.043148 (rank : 108)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	206	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

PRR13_MOUSE
NC score	0.034838 (rank : 109)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	206	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

ZCH13_HUMAN
NC score	0.033191 (rank : 110)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	206	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WW36	Gene names	ZCCHC13
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 13.

ACD_HUMAN
NC score	0.032756 (rank : 111)	θ value	1.06291 (rank : 116)
Query Neighborhood Hits	206	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

MADCA_HUMAN
NC score	0.031860 (rank : 112)	θ value	0.62314 (rank : 108)
Query Neighborhood Hits	206	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

RBM4_HUMAN
NC score	0.031731 (rank : 113)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	206	Target Neighborhood Hits	219	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BWF3, O02916, Q6P1P2, Q8WU85	Gene names	RBM4, RBM4A
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (hLark).

RBM4_MOUSE
NC score	0.031665 (rank : 114)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	206	Target Neighborhood Hits	223	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C7Q4, O08752, Q8BN66	Gene names	Rbm4, Rbm4a
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (mLark).

RBM4B_HUMAN
NC score	0.031279 (rank : 115)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	206	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQ04	Gene names	RBM4B, RBM30
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4B (RNA-binding motif protein 4B) (RNA-binding protein 30) (RNA-binding motif protein 30).

RBM4B_MOUSE
NC score	0.031248 (rank : 116)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	206	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VE92	Gene names	Rbm4b, Rbm30
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4B (RNA-binding motif protein 4B) (RNA-binding protein 30) (RNA-binding motif protein 30).

CBP_HUMAN
NC score	0.031022 (rank : 117)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	206	Target Neighborhood Hits	941	Shared Neighborhood Hits	35
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GFC1_HUMAN
NC score	0.028898 (rank : 118)	θ value	1.38821 (rank : 126)
Query Neighborhood Hits	206	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

BSN_HUMAN
NC score	0.028693 (rank : 119)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	206	Target Neighborhood Hits	1537	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CJ012_HUMAN
NC score	0.028451 (rank : 120)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	206	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CF125_HUMAN
NC score	0.027464 (rank : 121)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	206	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRT2	Gene names	C6orf125
Domain Architecture	No domain graphic available
Description	Protein C6orf125 (Breast cancer-associated protein SGA-81M).

BSN_MOUSE
NC score	0.026818 (rank : 122)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	206	Target Neighborhood Hits	2057	Shared Neighborhood Hits	59
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ZCHC6_HUMAN
NC score	0.026105 (rank : 123)	θ value	1.38821 (rank : 134)
Query Neighborhood Hits	206	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

MAP4_MOUSE
NC score	0.025953 (rank : 124)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	206	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

K0323_HUMAN
NC score	0.025578 (rank : 125)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	206	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

GAK2_HUMAN
NC score	0.025193 (rank : 126)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	206	Target Neighborhood Hits	406	Shared Neighborhood Hits	35
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.025117 (rank : 127)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	206	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

TBX15_HUMAN
NC score	0.025065 (rank : 128)	θ value	0.0252991 (rank : 78)
Query Neighborhood Hits	206	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q96SF7, Q5T9S7	Gene names	TBX15, TBX14
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX15 (T-box protein 15).

GAK5_HUMAN
NC score	0.025026 (rank : 129)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	206	Target Neighborhood Hits	429	Shared Neighborhood Hits	36
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CBP_MOUSE
NC score	0.025025 (rank : 130)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	206	Target Neighborhood Hits	1051	Shared Neighborhood Hits	34
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GAK11_HUMAN
NC score	0.024911 (rank : 131)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	206	Target Neighborhood Hits	409	Shared Neighborhood Hits	34
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK10_HUMAN
NC score	0.024889 (rank : 132)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	206	Target Neighborhood Hits	289	Shared Neighborhood Hits	32
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
NC score	0.024819 (rank : 133)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	206	Target Neighborhood Hits	374	Shared Neighborhood Hits	35
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
NC score	0.024663 (rank : 134)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	206	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PELP1_HUMAN
NC score	0.024430 (rank : 135)	θ value	1.38821 (rank : 129)
Query Neighborhood Hits	206	Target Neighborhood Hits	596	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

GAK6_HUMAN
NC score	0.024180 (rank : 136)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	206	Target Neighborhood Hits	392	Shared Neighborhood Hits	36
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SPG20_MOUSE
NC score	0.023790 (rank : 137)	θ value	1.38821 (rank : 132)
Query Neighborhood Hits	206	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1X6, Q6ZQ87, Q8BJD3, Q8BM37, Q8BZ63	Gene names	Spg20, Kiaa0610
Domain Architecture	No domain graphic available
Description	Spartin.

GAK3_HUMAN
NC score	0.023549 (rank : 138)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	206	Target Neighborhood Hits	182	Shared Neighborhood Hits	24
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ICAL_HUMAN
NC score	0.022423 (rank : 139)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	206	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ZO1_MOUSE
NC score	0.022216 (rank : 140)	θ value	0.0736092 (rank : 82)
Query Neighborhood Hits	206	Target Neighborhood Hits	453	Shared Neighborhood Hits	17
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CNOT3_MOUSE
NC score	0.021200 (rank : 141)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	206	Target Neighborhood Hits	504	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SACS_HUMAN
NC score	0.020161 (rank : 142)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	206	Target Neighborhood Hits	128	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

ZCH14_MOUSE
NC score	0.019689 (rank : 143)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	206	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

EP300_HUMAN
NC score	0.019450 (rank : 144)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	206	Target Neighborhood Hits	821	Shared Neighborhood Hits	28
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ZCH14_HUMAN
NC score	0.019013 (rank : 145)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	206	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

KIF3C_MOUSE
NC score	0.018789 (rank : 146)	θ value	0.0193708 (rank : 77)
Query Neighborhood Hits	206	Target Neighborhood Hits	468	Shared Neighborhood Hits	10
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

PACN1_HUMAN
NC score	0.018493 (rank : 147)	θ value	0.279714 (rank : 97)
Query Neighborhood Hits	206	Target Neighborhood Hits	320	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

TBX15_MOUSE
NC score	0.018478 (rank : 148)	θ value	1.38821 (rank : 133)
Query Neighborhood Hits	206	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	O70306, O54840	Gene names	Tbx15, Tbx14, Tbx8
Domain Architecture
Description	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8).

KIF3C_HUMAN
NC score	0.016254 (rank : 149)	θ value	0.21417 (rank : 94)
Query Neighborhood Hits	206	Target Neighborhood Hits	478	Shared Neighborhood Hits	13
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

BRAP_MOUSE
NC score	0.015619 (rank : 150)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	206	Target Neighborhood Hits	409	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

WBS14_HUMAN
NC score	0.015364 (rank : 151)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	206	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

PRG4_HUMAN
NC score	0.014989 (rank : 152)	θ value	1.06291 (rank : 119)
Query Neighborhood Hits	206	Target Neighborhood Hits	764	Shared Neighborhood Hits	28
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

LMBL3_MOUSE
NC score	0.014415 (rank : 153)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	206	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

NUCKS_MOUSE
NC score	0.014133 (rank : 154)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	206	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

AFF1_HUMAN
NC score	0.013971 (rank : 155)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	206	Target Neighborhood Hits	506	Shared Neighborhood Hits	16
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

DUS16_HUMAN
NC score	0.013827 (rank : 156)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	206	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

MITF_MOUSE
NC score	0.013807 (rank : 157)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	206	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

FBX34_MOUSE
NC score	0.013262 (rank : 158)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	206	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

CALD1_HUMAN
NC score	0.012965 (rank : 159)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	206	Target Neighborhood Hits	959	Shared Neighborhood Hits	16
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

PAD5_MOUSE
NC score	0.012460 (rank : 160)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	206	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q68ED3, Q8C0K6	Gene names	Papd5
Domain Architecture	No domain graphic available
Description	PAP-associated domain-containing protein 5 (EC 2.7.7.-) (Topoisomerase-related function protein 4-2) (TRF4-2).

SETB1_MOUSE
NC score	0.012453 (rank : 161)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	206	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

TLN1_HUMAN
NC score	0.012123 (rank : 162)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	206	Target Neighborhood Hits	218	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

SENP6_HUMAN
NC score	0.011593 (rank : 163)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	206	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

PACN1_MOUSE
NC score	0.011482 (rank : 164)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	206	Target Neighborhood Hits	283	Shared Neighborhood Hits	5
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

MYBPH_MOUSE
NC score	0.011214 (rank : 165)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	206	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

B4GN1_HUMAN
NC score	0.011089 (rank : 166)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	206	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q00973	Gene names	B4GALNT1, GALGT, SIAT2
Domain Architecture
Description	Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N- acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T).

CE005_HUMAN
NC score	0.010871 (rank : 167)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	206	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

NFH_MOUSE
NC score	0.010866 (rank : 168)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	206	Target Neighborhood Hits	2247	Shared Neighborhood Hits	55
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TLN1_MOUSE
NC score	0.010747 (rank : 169)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	206	Target Neighborhood Hits	213	Shared Neighborhood Hits	11
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

BNC2_MOUSE
NC score	0.010565 (rank : 170)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	206	Target Neighborhood Hits	456	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

PTN13_HUMAN
NC score	0.010439 (rank : 171)	θ value	0.21417 (rank : 95)
Query Neighborhood Hits	206	Target Neighborhood Hits	471	Shared Neighborhood Hits	9
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

CABP4_HUMAN
NC score	0.010145 (rank : 172)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	206	Target Neighborhood Hits	250	Shared Neighborhood Hits	6
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

KCNB2_HUMAN
NC score	0.009895 (rank : 173)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	206	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

LY75_MOUSE
NC score	0.009809 (rank : 174)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	206	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

CE005_MOUSE
NC score	0.009710 (rank : 175)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	206	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

BRAP_HUMAN
NC score	0.008908 (rank : 176)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	206	Target Neighborhood Hits	560	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

KCNN3_HUMAN
NC score	0.008754 (rank : 177)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	206	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

CCD96_HUMAN
NC score	0.008655 (rank : 178)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	206	Target Neighborhood Hits	595	Shared Neighborhood Hits	22
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CAF1B_MOUSE
NC score	0.008165 (rank : 179)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	206	Target Neighborhood Hits	385	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

MKL1_MOUSE
NC score	0.008098 (rank : 180)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	206	Target Neighborhood Hits	667	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

PHLPL_MOUSE
NC score	0.008030 (rank : 181)	θ value	0.62314 (rank : 109)
Query Neighborhood Hits	206	Target Neighborhood Hits	303	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

RIMB1_HUMAN
NC score	0.007925 (rank : 182)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	206	Target Neighborhood Hits	1479	Shared Neighborhood Hits	41
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SEZ6L_HUMAN
NC score	0.007277 (rank : 183)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	206	Target Neighborhood Hits	289	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

GCC2_MOUSE
NC score	0.006980 (rank : 184)	θ value	1.06291 (rank : 117)
Query Neighborhood Hits	206	Target Neighborhood Hits	1619	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

INADL_MOUSE
NC score	0.006940 (rank : 185)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	206	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

HCN3_HUMAN
NC score	0.006893 (rank : 186)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	206	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

ATBF1_HUMAN
NC score	0.006858 (rank : 187)	θ value	0.365318 (rank : 99)
Query Neighborhood Hits	206	Target Neighborhood Hits	1547	Shared Neighborhood Hits	16
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

EVPL_HUMAN
NC score	0.006814 (rank : 188)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	206	Target Neighborhood Hits	895	Shared Neighborhood Hits	20
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

BPA1_MOUSE
NC score	0.006510 (rank : 189)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	206	Target Neighborhood Hits	1477	Shared Neighborhood Hits	27
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GRAP1_MOUSE
NC score	0.006048 (rank : 190)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	206	Target Neighborhood Hits	1234	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

PTC1_HUMAN
NC score	0.005563 (rank : 191)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	206	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

COIA1_MOUSE
NC score	0.005416 (rank : 192)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	206	Target Neighborhood Hits	481	Shared Neighborhood Hits	16
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

PTPRN_MOUSE
NC score	0.005189 (rank : 193)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	206	Target Neighborhood Hits	240	Shared Neighborhood Hits	14
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

EVPL_MOUSE
NC score	0.004997 (rank : 194)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	206	Target Neighborhood Hits	952	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

EP400_MOUSE
NC score	0.004859 (rank : 195)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	206	Target Neighborhood Hits	592	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

IASPP_MOUSE
NC score	0.004567 (rank : 196)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	206	Target Neighborhood Hits	1024	Shared Neighborhood Hits	33
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

HV2I_HUMAN
NC score	0.004415 (rank : 197)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	206	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	P06331	Gene names
Domain Architecture	No domain graphic available
Description	Ig heavy chain V-II region ARH-77 precursor.

PDE1C_MOUSE
NC score	0.004250 (rank : 198)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	206	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

NCF1_HUMAN
NC score	0.003976 (rank : 199)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	206	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

GRAP1_HUMAN
NC score	0.003964 (rank : 200)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	206	Target Neighborhood Hits	944	Shared Neighborhood Hits	18
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

REST_MOUSE
NC score	0.003409 (rank : 201)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	206	Target Neighborhood Hits	1506	Shared Neighborhood Hits	34
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

PGCA_MOUSE
NC score	0.003339 (rank : 202)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	206	Target Neighborhood Hits	643	Shared Neighborhood Hits	11
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

INVS_MOUSE
NC score	0.003324 (rank : 203)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	206	Target Neighborhood Hits	609	Shared Neighborhood Hits	22
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

REST_HUMAN
NC score	0.003291 (rank : 204)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	206	Target Neighborhood Hits	1605	Shared Neighborhood Hits	30
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

NCA11_MOUSE
NC score	0.002289 (rank : 205)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	206	Target Neighborhood Hits	661	Shared Neighborhood Hits	14
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

BAI1_HUMAN
NC score	0.002065 (rank : 206)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	206	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BCOR_MOUSE
NC score	0.001628 (rank : 207)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	206	Target Neighborhood Hits	521	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

SPEG_MOUSE
NC score	0.001004 (rank : 208)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	206	Target Neighborhood Hits	1959	Shared Neighborhood Hits	48
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ANKS1_HUMAN
NC score	0.000167 (rank : 209)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	206	Target Neighborhood Hits	438	Shared Neighborhood Hits	6
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

CNR2_MOUSE
NC score	-0.000054 (rank : 210)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	206	Target Neighborhood Hits	738	Shared Neighborhood Hits	2
SwissProt Accessions	P47936	Gene names	Cnr2
Domain Architecture
Description	Cannabinoid receptor 2 (CB2) (CB-2).

PRDM2_HUMAN
NC score	-0.001899 (rank : 211)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	206	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

MK04_HUMAN
NC score	-0.002234 (rank : 212)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	206	Target Neighborhood Hits	837	Shared Neighborhood Hits	5
SwissProt Accessions	P31152	Gene names	MAPK4, ERK4, PRKM4
Domain Architecture
Description	Mitogen-activated protein kinase 4 (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63- MAPK).

F5006_HUMAN
NC score	-0.004439 (rank : 213)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	206	Target Neighborhood Hits	794	Shared Neighborhood Hits	5
SwissProt Accessions	Q96LW2, Q49A48	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

MLTK_HUMAN
NC score	-0.004829 (rank : 214)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	206	Target Neighborhood Hits	911	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).