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Network neighborhood for query Sequence : FBX34_MOUSE

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FBX34_MOUSE
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBX34_HUMAN
θ value	0 (rank : 1)	NC score	0.975093 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

FBX34_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

FBX46_HUMAN
θ value	3.23591e-74 (rank : 3)	NC score	0.867684 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

FBX46_MOUSE
θ value	8.81223e-72 (rank : 4)	NC score	0.849997 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

HUWE1_MOUSE
θ value	0.0193708 (rank : 5)	NC score	0.050846 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

RP1L1_HUMAN
θ value	0.0252991 (rank : 6)	NC score	0.044780 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	1072	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

BRWD1_MOUSE
θ value	0.0563607 (rank : 7)	NC score	0.025988 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	478	Shared Neighborhood Hits	4
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

GTSE1_MOUSE
θ value	0.0736092 (rank : 8)	NC score	0.064709 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

UN13A_HUMAN
θ value	0.0736092 (rank : 9)	NC score	0.037477 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

SOX9_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.030444 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	210	Shared Neighborhood Hits	5
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

HUWE1_HUMAN
θ value	0.163984 (rank : 11)	NC score	0.047123 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	443	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

ALO17_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.060635 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	317	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

DACH2_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.036810 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q96NX9, Q8NAY3, Q8ND17, Q96N55	Gene names	DACH2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

FXR2_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.027411 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

PRGR_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.015337 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

CTRO_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.010094 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	2092	Shared Neighborhood Hits	23
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SET1A_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.034665 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	690	Shared Neighborhood Hits	26
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

FXL21_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.039202 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

TP53B_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.042427 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	413	Shared Neighborhood Hits	19
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

FBX38_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.060107 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

FBX38_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.059924 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

MYST3_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.019644 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	772	Shared Neighborhood Hits	21
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NEK4_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.007397 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	883	Shared Neighborhood Hits	12
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

BCL9_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.028854 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	1008	Shared Neighborhood Hits	25
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CMTA2_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.038373 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.039327 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CTRO_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.009458 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	2344	Shared Neighborhood Hits	26
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

NU214_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.034919 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	657	Shared Neighborhood Hits	21
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

ACINU_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.033537 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	712	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACRBP_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.031535 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q3V140, Q62253, Q62254, Q8C621, Q91VQ1	Gene names	Acrbp
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32).

AFF1_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.021839 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ARID2_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.030574 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	302	Shared Neighborhood Hits	12
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

FXL21_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.034431 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

PTN23_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.012117 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	646	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SOX9_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.024191 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SP7_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.003252 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	734	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

TEC_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.007894 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	1006	Shared Neighborhood Hits	14
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TRI47_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.014774 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

WEE1_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.009693 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	794	Shared Neighborhood Hits	8
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

ABCA9_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.008656 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

BSCL2_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.037257 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	148	Shared Neighborhood Hits	8
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

NOL4_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.022991 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P60954	Gene names	Nol4
Domain Architecture	No domain graphic available
Description	Nucleolar protein 4.

RASA2_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.032703 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	159	Shared Neighborhood Hits	10
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

ASPX_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.030345 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

BASP_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.026187 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MILK1_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.013077 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PER3_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.017116 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PRG4_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.015094 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	764	Shared Neighborhood Hits	18
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRCA_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.020000 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	380	Shared Neighborhood Hits	17
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TRIO_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.006209 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	1580	Shared Neighborhood Hits	19
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

WWP2_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.026670 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ACINU_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.028610 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	828	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CD68_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.024205 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P34810, Q96BI7	Gene names	CD68
Domain Architecture
Description	Macrosialin precursor (GP110) (CD68 antigen).

IF39_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.019601 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

IF4G3_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.015645 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	279	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

MCE1_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.026911 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O55236	Gene names	Rngtt, Cap1a
Domain Architecture
Description	mRNA capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

MINT_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.018479 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	1291	Shared Neighborhood Hits	31
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFH_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.007314 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	1242	Shared Neighborhood Hits	24
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RAE1_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.014594 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXG2, Q80UV8	Gene names	Chm, Rep1
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein homolog).

RECQ4_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.013262 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

REXO1_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.018913 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

STK10_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.005966 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	1921	Shared Neighborhood Hits	29
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SYT10_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.010975 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

TEC_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.005954 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	1006	Shared Neighborhood Hits	14
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

ZN509_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.000244 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	846	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZSB9, Q59FJ4, Q5EBN0, Q8TB80	Gene names	ZNF509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN687_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.007106 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	913	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ARHG1_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.011400 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

CDN1C_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.019335 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CTND2_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.013320 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

DRAP1_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.022513 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

LMO7_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.017399 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	507	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

ARI1A_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.015905 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	787	Shared Neighborhood Hits	17
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

B3A3_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.009461 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

BCL9_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.026139 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	770	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CEND3_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.006229 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	228	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CUTL2_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.011036 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	771	Shared Neighborhood Hits	16
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

FILA_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.013898 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	685	Shared Neighborhood Hits	16
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

LIN9_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.015616 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q5TKA1, Q5U5L8, Q5U7E1, Q6PI55, Q6ZTV4, Q7Z3J1	Gene names	LIN9, BARA, TGS
Domain Architecture	No domain graphic available
Description	Lin-9 homolog (huLin-9) (hLin-9) (Beta-subunit associated regulator of apoptosis) (Type I interferon receptor beta chain-associated protein) (TUDOR gene similar protein) (pRB-associated protein).

LIPB1_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.007399 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	727	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

LMBL3_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.009788 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

MCE1_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.023946 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

MEFV_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.011323 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

RAB3I_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.014939 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	270	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

SHC3_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.012375 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.012731 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SYT6_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.009878 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

TACC1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.011414 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	597	Shared Neighborhood Hits	12
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TEX14_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.006547 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	1333	Shared Neighborhood Hits	19
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

BMP2K_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.005823 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CRTC1_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.013534 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	230	Shared Neighborhood Hits	11
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CTND2_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.012982 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	333	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

GON4L_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.021277 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	555	Shared Neighborhood Hits	23
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HCN2_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.013915 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	369	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

K0310_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.018079 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	420	Shared Neighborhood Hits	17
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

M4K4_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.004304 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	1589	Shared Neighborhood Hits	23
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

PLCB3_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.007339 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	344	Shared Neighborhood Hits	10
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

ROBO4_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.004341 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	358	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SYNPO_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.012050 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

ZHX2_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.010200 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	435	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

ZN691_HUMAN
θ value	8.99809 (rank : 100)	NC score	-0.000688 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	745	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VV52, O95878, Q9NWE8	Gene names	ZNF691
Domain Architecture	No domain graphic available
Description	Zinc finger protein 691.

Hits sorted by NC score

FBX34_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

FBX34_HUMAN
NC score	0.975093 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NWN3, Q2VPB5, Q86TY4	Gene names	FBXO34, FBX34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

FBX46_HUMAN
NC score	0.867684 (rank : 3)	θ value	3.23591e-74 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

FBX46_MOUSE
NC score	0.849997 (rank : 4)	θ value	8.81223e-72 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

GTSE1_MOUSE
NC score	0.064709 (rank : 5)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

ALO17_HUMAN
NC score	0.060635 (rank : 6)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	317	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

FBX38_HUMAN
NC score	0.060107 (rank : 7)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

FBX38_MOUSE
NC score	0.059924 (rank : 8)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

HUWE1_MOUSE
NC score	0.050846 (rank : 9)	θ value	0.0193708 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.047123 (rank : 10)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	443	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

RP1L1_HUMAN
NC score	0.044780 (rank : 11)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	1072	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TP53B_HUMAN
NC score	0.042427 (rank : 12)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	413	Shared Neighborhood Hits	19
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CMTA2_MOUSE
NC score	0.039327 (rank : 13)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

FXL21_HUMAN
NC score	0.039202 (rank : 14)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

CMTA2_HUMAN
NC score	0.038373 (rank : 15)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

UN13A_HUMAN
NC score	0.037477 (rank : 16)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

BSCL2_HUMAN
NC score	0.037257 (rank : 17)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	148	Shared Neighborhood Hits	8
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

DACH2_HUMAN
NC score	0.036810 (rank : 18)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q96NX9, Q8NAY3, Q8ND17, Q96N55	Gene names	DACH2
Domain Architecture
Description	Dachshund homolog 2 (Dach2).

NU214_HUMAN
NC score	0.034919 (rank : 19)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	657	Shared Neighborhood Hits	21
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SET1A_HUMAN
NC score	0.034665 (rank : 20)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	690	Shared Neighborhood Hits	26
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

FXL21_MOUSE
NC score	0.034431 (rank : 21)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

ACINU_MOUSE
NC score	0.033537 (rank : 22)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	712	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

RASA2_MOUSE
NC score	0.032703 (rank : 23)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	159	Shared Neighborhood Hits	10
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

ACRBP_MOUSE
NC score	0.031535 (rank : 24)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q3V140, Q62253, Q62254, Q8C621, Q91VQ1	Gene names	Acrbp
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32).

ARID2_HUMAN
NC score	0.030574 (rank : 25)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	302	Shared Neighborhood Hits	12
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

SOX9_HUMAN
NC score	0.030444 (rank : 26)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	210	Shared Neighborhood Hits	5
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

ASPX_MOUSE
NC score	0.030345 (rank : 27)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

BCL9_HUMAN
NC score	0.028854 (rank : 28)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	1008	Shared Neighborhood Hits	25
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

ACINU_HUMAN
NC score	0.028610 (rank : 29)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	828	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

FXR2_HUMAN
NC score	0.027411 (rank : 30)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

MCE1_MOUSE
NC score	0.026911 (rank : 31)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O55236	Gene names	Rngtt, Cap1a
Domain Architecture
Description	mRNA capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

WWP2_HUMAN
NC score	0.026670 (rank : 32)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

BASP_HUMAN
NC score	0.026187 (rank : 33)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BCL9_MOUSE
NC score	0.026139 (rank : 34)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	770	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BRWD1_MOUSE
NC score	0.025988 (rank : 35)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	478	Shared Neighborhood Hits	4
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CD68_HUMAN
NC score	0.024205 (rank : 36)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P34810, Q96BI7	Gene names	CD68
Domain Architecture
Description	Macrosialin precursor (GP110) (CD68 antigen).

SOX9_MOUSE
NC score	0.024191 (rank : 37)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

MCE1_HUMAN
NC score	0.023946 (rank : 38)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

NOL4_MOUSE
NC score	0.022991 (rank : 39)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P60954	Gene names	Nol4
Domain Architecture	No domain graphic available
Description	Nucleolar protein 4.

DRAP1_MOUSE
NC score	0.022513 (rank : 40)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

AFF1_HUMAN
NC score	0.021839 (rank : 41)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

GON4L_HUMAN
NC score	0.021277 (rank : 42)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	555	Shared Neighborhood Hits	23
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SRCA_HUMAN
NC score	0.020000 (rank : 43)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	380	Shared Neighborhood Hits	17
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

MYST3_HUMAN
NC score	0.019644 (rank : 44)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	772	Shared Neighborhood Hits	21
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

IF39_HUMAN
NC score	0.019601 (rank : 45)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

CDN1C_HUMAN
NC score	0.019335 (rank : 46)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

REXO1_HUMAN
NC score	0.018913 (rank : 47)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

MINT_HUMAN
NC score	0.018479 (rank : 48)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	1291	Shared Neighborhood Hits	31
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

K0310_HUMAN
NC score	0.018079 (rank : 49)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	420	Shared Neighborhood Hits	17
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

LMO7_HUMAN
NC score	0.017399 (rank : 50)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	507	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PER3_HUMAN
NC score	0.017116 (rank : 51)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

ARI1A_HUMAN
NC score	0.015905 (rank : 52)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	787	Shared Neighborhood Hits	17
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

IF4G3_MOUSE
NC score	0.015645 (rank : 53)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	279	Shared Neighborhood Hits	10
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

LIN9_HUMAN
NC score	0.015616 (rank : 54)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q5TKA1, Q5U5L8, Q5U7E1, Q6PI55, Q6ZTV4, Q7Z3J1	Gene names	LIN9, BARA, TGS
Domain Architecture	No domain graphic available
Description	Lin-9 homolog (huLin-9) (hLin-9) (Beta-subunit associated regulator of apoptosis) (Type I interferon receptor beta chain-associated protein) (TUDOR gene similar protein) (pRB-associated protein).

PRGR_MOUSE
NC score	0.015337 (rank : 55)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

PRG4_HUMAN
NC score	0.015094 (rank : 56)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	764	Shared Neighborhood Hits	18
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RAB3I_HUMAN
NC score	0.014939 (rank : 57)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	270	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

TRI47_MOUSE
NC score	0.014774 (rank : 58)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

RAE1_MOUSE
NC score	0.014594 (rank : 59)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXG2, Q80UV8	Gene names	Chm, Rep1
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein homolog).

HCN2_HUMAN
NC score	0.013915 (rank : 60)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	369	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

FILA_HUMAN
NC score	0.013898 (rank : 61)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	685	Shared Neighborhood Hits	16
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

CRTC1_MOUSE
NC score	0.013534 (rank : 62)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	230	Shared Neighborhood Hits	11
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

CTND2_MOUSE
NC score	0.013320 (rank : 63)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

RECQ4_MOUSE
NC score	0.013262 (rank : 64)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

MILK1_HUMAN
NC score	0.013077 (rank : 65)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CTND2_HUMAN
NC score	0.012982 (rank : 66)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	333	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

SHC3_MOUSE
NC score	0.012731 (rank : 67)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHC3_HUMAN
NC score	0.012375 (rank : 68)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

PTN23_HUMAN
NC score	0.012117 (rank : 69)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	646	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SYNPO_HUMAN
NC score	0.012050 (rank : 70)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TACC1_HUMAN
NC score	0.011414 (rank : 71)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	597	Shared Neighborhood Hits	12
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

ARHG1_MOUSE
NC score	0.011400 (rank : 72)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

MEFV_MOUSE
NC score	0.011323 (rank : 73)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

CUTL2_MOUSE
NC score	0.011036 (rank : 74)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	771	Shared Neighborhood Hits	16
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

SYT10_HUMAN
NC score	0.010975 (rank : 75)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

ZHX2_MOUSE
NC score	0.010200 (rank : 76)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	435	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

CTRO_HUMAN
NC score	0.010094 (rank : 77)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	2092	Shared Neighborhood Hits	23
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SYT6_MOUSE
NC score	0.009878 (rank : 78)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

LMBL3_MOUSE
NC score	0.009788 (rank : 79)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

WEE1_MOUSE
NC score	0.009693 (rank : 80)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	794	Shared Neighborhood Hits	8
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

B3A3_MOUSE
NC score	0.009461 (rank : 81)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

CTRO_MOUSE
NC score	0.009458 (rank : 82)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	2344	Shared Neighborhood Hits	26
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ABCA9_HUMAN
NC score	0.008656 (rank : 83)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

TEC_MOUSE
NC score	0.007894 (rank : 84)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	1006	Shared Neighborhood Hits	14
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

LIPB1_MOUSE
NC score	0.007399 (rank : 85)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	727	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

NEK4_HUMAN
NC score	0.007397 (rank : 86)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	883	Shared Neighborhood Hits	12
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

PLCB3_MOUSE
NC score	0.007339 (rank : 87)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	344	Shared Neighborhood Hits	10
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

NFH_HUMAN
NC score	0.007314 (rank : 88)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	1242	Shared Neighborhood Hits	24
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ZN687_MOUSE
NC score	0.007106 (rank : 89)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	913	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

TEX14_MOUSE
NC score	0.006547 (rank : 90)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	1333	Shared Neighborhood Hits	19
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CEND3_MOUSE
NC score	0.006229 (rank : 91)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	228	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

TRIO_HUMAN
NC score	0.006209 (rank : 92)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	1580	Shared Neighborhood Hits	19
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

STK10_HUMAN
NC score	0.005966 (rank : 93)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	1921	Shared Neighborhood Hits	29
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TEC_HUMAN
NC score	0.005954 (rank : 94)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	1006	Shared Neighborhood Hits	14
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

BMP2K_MOUSE
NC score	0.005823 (rank : 95)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

ROBO4_MOUSE
NC score	0.004341 (rank : 96)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	358	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

M4K4_HUMAN
NC score	0.004304 (rank : 97)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	1589	Shared Neighborhood Hits	23
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

SP7_HUMAN
NC score	0.003252 (rank : 98)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	734	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

ZN509_HUMAN
NC score	0.000244 (rank : 99)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	846	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZSB9, Q59FJ4, Q5EBN0, Q8TB80	Gene names	ZNF509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN691_HUMAN
NC score	-0.000688 (rank : 100)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	745	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VV52, O95878, Q9NWE8	Gene names	ZNF691
Domain Architecture	No domain graphic available
Description	Zinc finger protein 691.