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Network neighborhood for query Sequence : SOX9_HUMAN

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SOX9_HUMAN
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SOX9_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	210
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_MOUSE
θ value	0 (rank : 2)	NC score	0.992769 (rank : 2)
Query Neighborhood Hits	210	Target Neighborhood Hits	188	Shared Neighborhood Hits	148
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX10_HUMAN
θ value	1.25199e-126 (rank : 3)	NC score	0.976263 (rank : 5)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	80
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX10_MOUSE
θ value	1.25199e-126 (rank : 4)	NC score	0.977116 (rank : 3)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	80
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX8_MOUSE
θ value	2.37764e-101 (rank : 5)	NC score	0.976627 (rank : 4)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	77
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX8_HUMAN
θ value	1.65039e-94 (rank : 6)	NC score	0.976107 (rank : 6)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX17_MOUSE
θ value	3.74554e-30 (rank : 7)	NC score	0.897949 (rank : 29)
Query Neighborhood Hits	210	Target Neighborhood Hits	223	Shared Neighborhood Hits	88
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX17_HUMAN
θ value	4.89182e-30 (rank : 8)	NC score	0.908700 (rank : 19)
Query Neighborhood Hits	210	Target Neighborhood Hits	108	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX18_MOUSE
θ value	1.33217e-27 (rank : 9)	NC score	0.913286 (rank : 15)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	79
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX21_HUMAN
θ value	1.33217e-27 (rank : 10)	NC score	0.918045 (rank : 11)
Query Neighborhood Hits	210	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX21_MOUSE
θ value	1.33217e-27 (rank : 11)	NC score	0.918063 (rank : 10)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX7_MOUSE
θ value	1.33217e-27 (rank : 12)	NC score	0.898122 (rank : 28)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	77
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX18_HUMAN
θ value	2.27234e-27 (rank : 13)	NC score	0.913211 (rank : 16)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	79
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX14_HUMAN
θ value	2.96777e-27 (rank : 14)	NC score	0.908287 (rank : 21)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_MOUSE
θ value	2.96777e-27 (rank : 15)	NC score	0.908293 (rank : 20)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX7_HUMAN
θ value	6.61148e-27 (rank : 16)	NC score	0.892600 (rank : 32)
Query Neighborhood Hits	210	Target Neighborhood Hits	140	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX2_HUMAN
θ value	8.63488e-27 (rank : 17)	NC score	0.899248 (rank : 26)
Query Neighborhood Hits	210	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
θ value	8.63488e-27 (rank : 18)	NC score	0.898896 (rank : 27)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX12_HUMAN
θ value	1.92365e-26 (rank : 19)	NC score	0.931695 (rank : 8)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX12_MOUSE
θ value	1.92365e-26 (rank : 20)	NC score	0.934212 (rank : 7)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX1_MOUSE
θ value	1.92365e-26 (rank : 21)	NC score	0.905010 (rank : 24)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX4_MOUSE
θ value	2.51237e-26 (rank : 22)	NC score	0.912989 (rank : 17)
Query Neighborhood Hits	210	Target Neighborhood Hits	108	Shared Neighborhood Hits	79
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX1_HUMAN
θ value	4.28545e-26 (rank : 23)	NC score	0.906084 (rank : 22)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX4_HUMAN
θ value	4.28545e-26 (rank : 24)	NC score	0.915635 (rank : 13)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	81
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX15_HUMAN
θ value	1.24688e-25 (rank : 25)	NC score	0.912652 (rank : 18)
Query Neighborhood Hits	210	Target Neighborhood Hits	134	Shared Neighborhood Hits	80
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX11_HUMAN
θ value	2.77775e-25 (rank : 26)	NC score	0.918202 (rank : 9)
Query Neighborhood Hits	210	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX11_MOUSE
θ value	2.77775e-25 (rank : 27)	NC score	0.915878 (rank : 12)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	80
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX15_MOUSE
θ value	1.05554e-24 (rank : 28)	NC score	0.915325 (rank : 14)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX3_MOUSE
θ value	2.35151e-24 (rank : 29)	NC score	0.902342 (rank : 25)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	80
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX3_HUMAN
θ value	3.07116e-24 (rank : 30)	NC score	0.897651 (rank : 30)
Query Neighborhood Hits	210	Target Neighborhood Hits	109	Shared Neighborhood Hits	80
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SRY_MOUSE
θ value	1.5242e-23 (rank : 31)	NC score	0.892944 (rank : 31)
Query Neighborhood Hits	210	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX5_HUMAN
θ value	6.40375e-22 (rank : 32)	NC score	0.815461 (rank : 34)
Query Neighborhood Hits	210	Target Neighborhood Hits	219	Shared Neighborhood Hits	90
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
θ value	6.40375e-22 (rank : 33)	NC score	0.817362 (rank : 33)
Query Neighborhood Hits	210	Target Neighborhood Hits	196	Shared Neighborhood Hits	88
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX13_HUMAN
θ value	5.42112e-21 (rank : 34)	NC score	0.791993 (rank : 38)
Query Neighborhood Hits	210	Target Neighborhood Hits	464	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
θ value	5.42112e-21 (rank : 35)	NC score	0.794952 (rank : 37)
Query Neighborhood Hits	210	Target Neighborhood Hits	495	Shared Neighborhood Hits	99
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX6_HUMAN
θ value	3.51386e-20 (rank : 36)	NC score	0.796561 (rank : 35)
Query Neighborhood Hits	210	Target Neighborhood Hits	332	Shared Neighborhood Hits	90
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
θ value	3.51386e-20 (rank : 37)	NC score	0.795839 (rank : 36)
Query Neighborhood Hits	210	Target Neighborhood Hits	341	Shared Neighborhood Hits	90
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SRY_HUMAN
θ value	1.02238e-19 (rank : 38)	NC score	0.905365 (rank : 23)
Query Neighborhood Hits	210	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX30_HUMAN
θ value	6.20254e-17 (rank : 39)	NC score	0.788444 (rank : 40)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	96
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX30_MOUSE
θ value	5.25075e-16 (rank : 40)	NC score	0.791960 (rank : 39)
Query Neighborhood Hits	210	Target Neighborhood Hits	374	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

CIC_HUMAN
θ value	1.2105e-12 (rank : 41)	NC score	0.615675 (rank : 46)
Query Neighborhood Hits	210	Target Neighborhood Hits	992	Shared Neighborhood Hits	142
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	7.84624e-12 (rank : 42)	NC score	0.651222 (rank : 43)
Query Neighborhood Hits	210	Target Neighborhood Hits	742	Shared Neighborhood Hits	135
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TF7L1_MOUSE
θ value	4.76016e-09 (rank : 43)	NC score	0.564019 (rank : 55)
Query Neighborhood Hits	210	Target Neighborhood Hits	131	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

HMGB3_HUMAN
θ value	8.11959e-09 (rank : 44)	NC score	0.610447 (rank : 48)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

TF7L1_HUMAN
θ value	2.36244e-08 (rank : 45)	NC score	0.561535 (rank : 56)
Query Neighborhood Hits	210	Target Neighborhood Hits	129	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

HMGB3_MOUSE
θ value	5.26297e-08 (rank : 46)	NC score	0.600446 (rank : 49)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

SSRP1_HUMAN
θ value	8.97725e-08 (rank : 47)	NC score	0.567753 (rank : 54)
Query Neighborhood Hits	210	Target Neighborhood Hits	187	Shared Neighborhood Hits	81
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_MOUSE
θ value	1.17247e-07 (rank : 48)	NC score	0.574110 (rank : 51)
Query Neighborhood Hits	210	Target Neighborhood Hits	193	Shared Neighborhood Hits	81
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

HBP1_HUMAN
θ value	2.61198e-07 (rank : 49)	NC score	0.659900 (rank : 42)
Query Neighborhood Hits	210	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_MOUSE
θ value	2.61198e-07 (rank : 50)	NC score	0.660060 (rank : 41)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

BBX_HUMAN
θ value	3.41135e-07 (rank : 51)	NC score	0.628229 (rank : 44)
Query Neighborhood Hits	210	Target Neighborhood Hits	167	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

TF7L2_HUMAN
θ value	4.45536e-07 (rank : 52)	NC score	0.571892 (rank : 53)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L2_MOUSE
θ value	4.45536e-07 (rank : 53)	NC score	0.573902 (rank : 52)
Query Neighborhood Hits	210	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

BBX_MOUSE
θ value	7.59969e-07 (rank : 54)	NC score	0.619081 (rank : 45)
Query Neighborhood Hits	210	Target Neighborhood Hits	152	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

TCF7_HUMAN
θ value	9.92553e-07 (rank : 55)	NC score	0.614737 (rank : 47)
Query Neighborhood Hits	210	Target Neighborhood Hits	186	Shared Neighborhood Hits	80
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TCF7_MOUSE
θ value	1.69304e-06 (rank : 56)	NC score	0.580325 (rank : 50)
Query Neighborhood Hits	210	Target Neighborhood Hits	277	Shared Neighborhood Hits	78
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

HMGB2_HUMAN
θ value	4.92598e-06 (rank : 57)	NC score	0.551423 (rank : 59)
Query Neighborhood Hits	210	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_MOUSE
θ value	1.09739e-05 (rank : 58)	NC score	0.539782 (rank : 60)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	76
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB1_HUMAN
θ value	1.43324e-05 (rank : 59)	NC score	0.513132 (rank : 63)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	76
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	1.43324e-05 (rank : 60)	NC score	0.513210 (rank : 62)
Query Neighborhood Hits	210	Target Neighborhood Hits	123	Shared Neighborhood Hits	76
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

LEF1_HUMAN
θ value	1.43324e-05 (rank : 61)	NC score	0.560619 (rank : 57)
Query Neighborhood Hits	210	Target Neighborhood Hits	150	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
θ value	1.43324e-05 (rank : 62)	NC score	0.559813 (rank : 58)
Query Neighborhood Hits	210	Target Neighborhood Hits	161	Shared Neighborhood Hits	79
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

HMG1X_HUMAN
θ value	3.19293e-05 (rank : 63)	NC score	0.481525 (rank : 65)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

UBF1_HUMAN
θ value	0.00020696 (rank : 64)	NC score	0.462258 (rank : 66)
Query Neighborhood Hits	210	Target Neighborhood Hits	415	Shared Neighborhood Hits	83
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBF1_MOUSE
θ value	0.000270298 (rank : 65)	NC score	0.454919 (rank : 67)
Query Neighborhood Hits	210	Target Neighborhood Hits	419	Shared Neighborhood Hits	84
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

HM20B_HUMAN
θ value	0.000602161 (rank : 66)	NC score	0.522775 (rank : 61)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

RGS3_MOUSE
θ value	0.00134147 (rank : 67)	NC score	0.042265 (rank : 117)
Query Neighborhood Hits	210	Target Neighborhood Hits	1621	Shared Neighborhood Hits	81
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

HM20B_MOUSE
θ value	0.00228821 (rank : 68)	NC score	0.502430 (rank : 64)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

LPP_HUMAN
θ value	0.00228821 (rank : 69)	NC score	0.052796 (rank : 107)
Query Neighborhood Hits	210	Target Neighborhood Hits	775	Shared Neighborhood Hits	49
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

HM20A_HUMAN
θ value	0.00509761 (rank : 70)	NC score	0.429847 (rank : 69)
Query Neighborhood Hits	210	Target Neighborhood Hits	343	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	0.00509761 (rank : 71)	NC score	0.428283 (rank : 70)
Query Neighborhood Hits	210	Target Neighborhood Hits	348	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

PB1_HUMAN
θ value	0.00665767 (rank : 72)	NC score	0.284892 (rank : 75)
Query Neighborhood Hits	210	Target Neighborhood Hits	261	Shared Neighborhood Hits	91
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

SP100_HUMAN
θ value	0.0113563 (rank : 73)	NC score	0.292783 (rank : 74)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

HM2L1_HUMAN
θ value	0.0148317 (rank : 74)	NC score	0.443855 (rank : 68)
Query Neighborhood Hits	210	Target Neighborhood Hits	130	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

GAK5_HUMAN
θ value	0.0193708 (rank : 75)	NC score	0.062919 (rank : 87)
Query Neighborhood Hits	210	Target Neighborhood Hits	429	Shared Neighborhood Hits	41
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
θ value	0.0252991 (rank : 76)	NC score	0.062154 (rank : 90)
Query Neighborhood Hits	210	Target Neighborhood Hits	409	Shared Neighborhood Hits	39
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	0.0252991 (rank : 77)	NC score	0.062473 (rank : 88)
Query Neighborhood Hits	210	Target Neighborhood Hits	374	Shared Neighborhood Hits	38
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	0.0252991 (rank : 78)	NC score	0.062354 (rank : 89)
Query Neighborhood Hits	210	Target Neighborhood Hits	415	Shared Neighborhood Hits	40
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	0.0252991 (rank : 79)	NC score	0.059877 (rank : 94)
Query Neighborhood Hits	210	Target Neighborhood Hits	392	Shared Neighborhood Hits	38
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	0.0330416 (rank : 80)	NC score	0.061362 (rank : 91)
Query Neighborhood Hits	210	Target Neighborhood Hits	406	Shared Neighborhood Hits	37
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

R3HD2_MOUSE
θ value	0.0330416 (rank : 81)	NC score	0.064251 (rank : 86)
Query Neighborhood Hits	210	Target Neighborhood Hits	397	Shared Neighborhood Hits	44
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RPB1_HUMAN
θ value	0.0330416 (rank : 82)	NC score	0.066185 (rank : 84)
Query Neighborhood Hits	210	Target Neighborhood Hits	362	Shared Neighborhood Hits	47
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.0330416 (rank : 83)	NC score	0.066477 (rank : 83)
Query Neighborhood Hits	210	Target Neighborhood Hits	363	Shared Neighborhood Hits	48
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TARSH_HUMAN
θ value	0.0330416 (rank : 84)	NC score	0.054306 (rank : 104)
Query Neighborhood Hits	210	Target Neighborhood Hits	768	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MYO15_MOUSE
θ value	0.0736092 (rank : 85)	NC score	0.015540 (rank : 171)
Query Neighborhood Hits	210	Target Neighborhood Hits	467	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

OBSCN_HUMAN
θ value	0.0736092 (rank : 86)	NC score	0.004012 (rank : 201)
Query Neighborhood Hits	210	Target Neighborhood Hits	1931	Shared Neighborhood Hits	56
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PCLO_MOUSE
θ value	0.0961366 (rank : 87)	NC score	0.043512 (rank : 116)
Query Neighborhood Hits	210	Target Neighborhood Hits	2275	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SMCE1_HUMAN
θ value	0.0961366 (rank : 88)	NC score	0.322060 (rank : 72)
Query Neighborhood Hits	210	Target Neighborhood Hits	272	Shared Neighborhood Hits	67
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
θ value	0.0961366 (rank : 89)	NC score	0.303004 (rank : 73)
Query Neighborhood Hits	210	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

FBX34_MOUSE
θ value	0.125558 (rank : 90)	NC score	0.030444 (rank : 134)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

JHD2C_MOUSE
θ value	0.163984 (rank : 91)	NC score	0.029534 (rank : 139)
Query Neighborhood Hits	210	Target Neighborhood Hits	297	Shared Neighborhood Hits	25
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

RPKL1_MOUSE
θ value	0.163984 (rank : 92)	NC score	0.003914 (rank : 203)
Query Neighborhood Hits	210	Target Neighborhood Hits	704	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

TRI66_HUMAN
θ value	0.163984 (rank : 93)	NC score	0.037623 (rank : 123)
Query Neighborhood Hits	210	Target Neighborhood Hits	479	Shared Neighborhood Hits	51
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PKNX2_MOUSE
θ value	0.21417 (rank : 94)	NC score	0.019494 (rank : 164)
Query Neighborhood Hits	210	Target Neighborhood Hits	197	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

TULP4_HUMAN
θ value	0.21417 (rank : 95)	NC score	0.021538 (rank : 156)
Query Neighborhood Hits	210	Target Neighborhood Hits	426	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

BTBD7_MOUSE
θ value	0.279714 (rank : 96)	NC score	0.020680 (rank : 159)
Query Neighborhood Hits	210	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

GRIN1_MOUSE
θ value	0.279714 (rank : 97)	NC score	0.033669 (rank : 129)
Query Neighborhood Hits	210	Target Neighborhood Hits	337	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

APBB2_MOUSE
θ value	0.365318 (rank : 98)	NC score	0.021122 (rank : 158)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

ARI1A_HUMAN
θ value	0.365318 (rank : 99)	NC score	0.065647 (rank : 85)
Query Neighborhood Hits	210	Target Neighborhood Hits	787	Shared Neighborhood Hits	84
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATX2L_HUMAN
θ value	0.365318 (rank : 100)	NC score	0.056129 (rank : 100)
Query Neighborhood Hits	210	Target Neighborhood Hits	443	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2L_MOUSE
θ value	0.365318 (rank : 101)	NC score	0.050868 (rank : 111)
Query Neighborhood Hits	210	Target Neighborhood Hits	401	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

EST1A_HUMAN
θ value	0.365318 (rank : 102)	NC score	0.028271 (rank : 142)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

SMAL1_HUMAN
θ value	0.365318 (rank : 103)	NC score	0.016368 (rank : 168)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

AL2S4_MOUSE
θ value	0.47712 (rank : 104)	NC score	0.039111 (rank : 122)
Query Neighborhood Hits	210	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

BTBDC_HUMAN
θ value	0.47712 (rank : 105)	NC score	0.044317 (rank : 113)
Query Neighborhood Hits	210	Target Neighborhood Hits	248	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

ENAM_HUMAN
θ value	0.47712 (rank : 106)	NC score	0.039830 (rank : 121)
Query Neighborhood Hits	210	Target Neighborhood Hits	227	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

GAK10_HUMAN
θ value	0.47712 (rank : 107)	NC score	0.057655 (rank : 96)
Query Neighborhood Hits	210	Target Neighborhood Hits	289	Shared Neighborhood Hits	31
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NOTC2_MOUSE
θ value	0.47712 (rank : 108)	NC score	0.001333 (rank : 212)
Query Neighborhood Hits	210	Target Neighborhood Hits	1069	Shared Neighborhood Hits	32
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TFAM_MOUSE
θ value	0.47712 (rank : 109)	NC score	0.331033 (rank : 71)
Query Neighborhood Hits	210	Target Neighborhood Hits	93	Shared Neighborhood Hits	73
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

BRD4_HUMAN
θ value	0.62314 (rank : 110)	NC score	0.055821 (rank : 101)
Query Neighborhood Hits	210	Target Neighborhood Hits	851	Shared Neighborhood Hits	84
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CEL_HUMAN
θ value	0.62314 (rank : 111)	NC score	0.019548 (rank : 163)
Query Neighborhood Hits	210	Target Neighborhood Hits	896	Shared Neighborhood Hits	50
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

TFEB_HUMAN
θ value	0.62314 (rank : 112)	NC score	0.034804 (rank : 127)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.62314 (rank : 113)	NC score	0.034379 (rank : 128)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

CD2_HUMAN
θ value	0.813845 (rank : 114)	NC score	0.054881 (rank : 103)
Query Neighborhood Hits	210	Target Neighborhood Hits	504	Shared Neighborhood Hits	49
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

GTSE1_MOUSE
θ value	0.813845 (rank : 115)	NC score	0.032551 (rank : 132)
Query Neighborhood Hits	210	Target Neighborhood Hits	245	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

JHD2C_HUMAN
θ value	0.813845 (rank : 116)	NC score	0.024329 (rank : 147)
Query Neighborhood Hits	210	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

TACC2_HUMAN
θ value	0.813845 (rank : 117)	NC score	0.011164 (rank : 183)
Query Neighborhood Hits	210	Target Neighborhood Hits	856	Shared Neighborhood Hits	28
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

BAT2_HUMAN
θ value	1.06291 (rank : 118)	NC score	0.060912 (rank : 92)
Query Neighborhood Hits	210	Target Neighborhood Hits	931	Shared Neighborhood Hits	86
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EST1A_MOUSE
θ value	1.06291 (rank : 119)	NC score	0.030877 (rank : 133)
Query Neighborhood Hits	210	Target Neighborhood Hits	138	Shared Neighborhood Hits	9
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

GLI3_HUMAN
θ value	1.06291 (rank : 120)	NC score	-0.002561 (rank : 217)
Query Neighborhood Hits	210	Target Neighborhood Hits	871	Shared Neighborhood Hits	21
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

NFH_MOUSE
θ value	1.06291 (rank : 121)	NC score	0.023839 (rank : 148)
Query Neighborhood Hits	210	Target Neighborhood Hits	2247	Shared Neighborhood Hits	83
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PMS1_HUMAN
θ value	1.06291 (rank : 122)	NC score	0.246203 (rank : 77)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

ALMS1_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.025669 (rank : 146)
Query Neighborhood Hits	210	Target Neighborhood Hits	356	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

ZN414_MOUSE
θ value	1.38821 (rank : 124)	NC score	0.011899 (rank : 179)
Query Neighborhood Hits	210	Target Neighborhood Hits	473	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

GPTC8_HUMAN
θ value	1.81305 (rank : 125)	NC score	0.023755 (rank : 149)
Query Neighborhood Hits	210	Target Neighborhood Hits	366	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

NCOA6_HUMAN
θ value	1.81305 (rank : 126)	NC score	0.044794 (rank : 112)
Query Neighborhood Hits	210	Target Neighborhood Hits	1202	Shared Neighborhood Hits	89
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SH22A_MOUSE
θ value	1.81305 (rank : 127)	NC score	0.020386 (rank : 160)
Query Neighborhood Hits	210	Target Neighborhood Hits	179	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

TRI66_MOUSE
θ value	1.81305 (rank : 128)	NC score	0.029428 (rank : 140)
Query Neighborhood Hits	210	Target Neighborhood Hits	491	Shared Neighborhood Hits	44
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TXND2_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.022601 (rank : 153)
Query Neighborhood Hits	210	Target Neighborhood Hits	793	Shared Neighborhood Hits	41
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ADA12_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.003936 (rank : 202)
Query Neighborhood Hits	210	Target Neighborhood Hits	474	Shared Neighborhood Hits	21
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BOC_HUMAN
θ value	2.36792 (rank : 131)	NC score	0.003251 (rank : 206)
Query Neighborhood Hits	210	Target Neighborhood Hits	543	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

ETV4_MOUSE
θ value	2.36792 (rank : 132)	NC score	0.007456 (rank : 194)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

LPP_MOUSE
θ value	2.36792 (rank : 133)	NC score	0.022541 (rank : 154)
Query Neighborhood Hits	210	Target Neighborhood Hits	247	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

MRCKB_HUMAN
θ value	2.36792 (rank : 134)	NC score	-0.002807 (rank : 220)
Query Neighborhood Hits	210	Target Neighborhood Hits	2239	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYCD_MOUSE
θ value	2.36792 (rank : 135)	NC score	0.013566 (rank : 177)
Query Neighborhood Hits	210	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

MYCL1_HUMAN
θ value	2.36792 (rank : 136)	NC score	0.011470 (rank : 181)
Query Neighborhood Hits	210	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NCOA6_MOUSE
θ value	2.36792 (rank : 137)	NC score	0.040924 (rank : 119)
Query Neighborhood Hits	210	Target Neighborhood Hits	1076	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PKCB1_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.027406 (rank : 143)
Query Neighborhood Hits	210	Target Neighborhood Hits	488	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PTN12_MOUSE
θ value	2.36792 (rank : 139)	NC score	0.007019 (rank : 195)
Query Neighborhood Hits	210	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

RC3H1_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.016993 (rank : 166)
Query Neighborhood Hits	210	Target Neighborhood Hits	433	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

SH2D3_HUMAN
θ value	2.36792 (rank : 141)	NC score	0.013144 (rank : 178)
Query Neighborhood Hits	210	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

ZN217_HUMAN
θ value	2.36792 (rank : 142)	NC score	0.000456 (rank : 213)
Query Neighborhood Hits	210	Target Neighborhood Hits	905	Shared Neighborhood Hits	21
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

BAT2_MOUSE
θ value	3.0926 (rank : 143)	NC score	0.053874 (rank : 105)
Query Neighborhood Hits	210	Target Neighborhood Hits	947	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CAMKV_HUMAN
θ value	3.0926 (rank : 144)	NC score	-0.002717 (rank : 218)
Query Neighborhood Hits	210	Target Neighborhood Hits	1084	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

K0999_MOUSE
θ value	3.0926 (rank : 145)	NC score	-0.002944 (rank : 221)
Query Neighborhood Hits	210	Target Neighborhood Hits	931	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

PCLO_HUMAN
θ value	3.0926 (rank : 146)	NC score	0.041543 (rank : 118)
Query Neighborhood Hits	210	Target Neighborhood Hits	2046	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PKNX2_HUMAN
θ value	3.0926 (rank : 147)	NC score	0.015435 (rank : 172)
Query Neighborhood Hits	210	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

SYNJ1_MOUSE
θ value	3.0926 (rank : 148)	NC score	0.029200 (rank : 141)
Query Neighborhood Hits	210	Target Neighborhood Hits	516	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TENS4_HUMAN
θ value	3.0926 (rank : 149)	NC score	0.016330 (rank : 169)
Query Neighborhood Hits	210	Target Neighborhood Hits	214	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

AIRE_MOUSE
θ value	4.03905 (rank : 150)	NC score	0.019662 (rank : 162)
Query Neighborhood Hits	210	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

CAC1G_HUMAN
θ value	4.03905 (rank : 151)	NC score	0.006309 (rank : 198)
Query Neighborhood Hits	210	Target Neighborhood Hits	587	Shared Neighborhood Hits	33
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

FA47A_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.026176 (rank : 145)
Query Neighborhood Hits	210	Target Neighborhood Hits	451	Shared Neighborhood Hits	46
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

GPS2_HUMAN
θ value	4.03905 (rank : 153)	NC score	0.034934 (rank : 126)
Query Neighborhood Hits	210	Target Neighborhood Hits	459	Shared Neighborhood Hits	32
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

HELZ_HUMAN
θ value	4.03905 (rank : 154)	NC score	0.022772 (rank : 151)
Query Neighborhood Hits	210	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

LCP2_HUMAN
θ value	4.03905 (rank : 155)	NC score	0.029822 (rank : 138)
Query Neighborhood Hits	210	Target Neighborhood Hits	531	Shared Neighborhood Hits	47
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LIPS_HUMAN
θ value	4.03905 (rank : 156)	NC score	0.033613 (rank : 130)
Query Neighborhood Hits	210	Target Neighborhood Hits	314	Shared Neighborhood Hits	34
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MLL3_HUMAN
θ value	4.03905 (rank : 157)	NC score	0.036471 (rank : 125)
Query Neighborhood Hits	210	Target Neighborhood Hits	1644	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ZN516_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.004831 (rank : 200)
Query Neighborhood Hits	210	Target Neighborhood Hits	1197	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ANK2_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.013767 (rank : 176)
Query Neighborhood Hits	210	Target Neighborhood Hits	1615	Shared Neighborhood Hits	76
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR15_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.009289 (rank : 190)
Query Neighborhood Hits	210	Target Neighborhood Hits	478	Shared Neighborhood Hits	13
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

APBB2_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.014526 (rank : 174)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

ARHGB_HUMAN
θ value	5.27518 (rank : 162)	NC score	0.007549 (rank : 193)
Query Neighborhood Hits	210	Target Neighborhood Hits	375	Shared Neighborhood Hits	19
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

CP3AB_MOUSE
θ value	5.27518 (rank : 163)	NC score	0.002353 (rank : 210)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q64459	Gene names	Cyp3a11, Cyp3a-11
Domain Architecture
Description	Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11) (P-450IIIAM1) (P- 450UT).

ECM1_MOUSE
θ value	5.27518 (rank : 164)	NC score	0.014071 (rank : 175)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

IWS1_MOUSE
θ value	5.27518 (rank : 165)	NC score	0.018143 (rank : 165)
Query Neighborhood Hits	210	Target Neighborhood Hits	1258	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MAML3_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.026468 (rank : 144)
Query Neighborhood Hits	210	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

NIPBL_HUMAN
θ value	5.27518 (rank : 167)	NC score	0.030418 (rank : 135)
Query Neighborhood Hits	210	Target Neighborhood Hits	1311	Shared Neighborhood Hits	64
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.030153 (rank : 136)
Query Neighborhood Hits	210	Target Neighborhood Hits	1041	Shared Neighborhood Hits	61
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

P2RX2_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.009327 (rank : 189)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

PF21A_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.015555 (rank : 170)
Query Neighborhood Hits	210	Target Neighborhood Hits	303	Shared Neighborhood Hits	17
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	5.27518 (rank : 171)	NC score	0.016521 (rank : 167)
Query Neighborhood Hits	210	Target Neighborhood Hits	285	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PI5PA_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.030087 (rank : 137)
Query Neighborhood Hits	210	Target Neighborhood Hits	749	Shared Neighborhood Hits	55
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRRT3_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.040390 (rank : 120)
Query Neighborhood Hits	210	Target Neighborhood Hits	998	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RERE_HUMAN
θ value	5.27518 (rank : 174)	NC score	0.059990 (rank : 93)
Query Neighborhood Hits	210	Target Neighborhood Hits	779	Shared Neighborhood Hits	92
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SPEG_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.003204 (rank : 207)
Query Neighborhood Hits	210	Target Neighborhood Hits	1959	Shared Neighborhood Hits	75
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

AFAD_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.006572 (rank : 197)
Query Neighborhood Hits	210	Target Neighborhood Hits	689	Shared Neighborhood Hits	25
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ATN1_HUMAN
θ value	6.88961 (rank : 177)	NC score	0.056246 (rank : 99)
Query Neighborhood Hits	210	Target Neighborhood Hits	676	Shared Neighborhood Hits	73
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CABIN_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.022801 (rank : 150)
Query Neighborhood Hits	210	Target Neighborhood Hits	490	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CP341_MOUSE
θ value	6.88961 (rank : 179)	NC score	0.001747 (rank : 211)
Query Neighborhood Hits	210	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JMA7	Gene names	Cyp3a41
Domain Architecture
Description	Cytochrome P450 3A41 (EC 1.14.14.1).

CRTC1_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.053512 (rank : 106)
Query Neighborhood Hits	210	Target Neighborhood Hits	319	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

EHMT2_MOUSE
θ value	6.88961 (rank : 181)	NC score	0.006088 (rank : 199)
Query Neighborhood Hits	210	Target Neighborhood Hits	750	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ILF3_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.011113 (rank : 184)
Query Neighborhood Hits	210	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

INVS_MOUSE
θ value	6.88961 (rank : 183)	NC score	0.003817 (rank : 204)
Query Neighborhood Hits	210	Target Neighborhood Hits	609	Shared Neighborhood Hits	30
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

K1683_HUMAN
θ value	6.88961 (rank : 184)	NC score	0.020275 (rank : 161)
Query Neighborhood Hits	210	Target Neighborhood Hits	240	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KCNQ5_HUMAN
θ value	6.88961 (rank : 185)	NC score	0.003338 (rank : 205)
Query Neighborhood Hits	210	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

NCOA2_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.007648 (rank : 192)
Query Neighborhood Hits	210	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NFAC1_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.011499 (rank : 180)
Query Neighborhood Hits	210	Target Neighborhood Hits	312	Shared Neighborhood Hits	36
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PHC2_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.021849 (rank : 155)
Query Neighborhood Hits	210	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PRC1_HUMAN
θ value	6.88961 (rank : 189)	NC score	0.010756 (rank : 186)
Query Neighborhood Hits	210	Target Neighborhood Hits	328	Shared Neighborhood Hits	10
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

PRC1_MOUSE
θ value	6.88961 (rank : 190)	NC score	0.009701 (rank : 187)
Query Neighborhood Hits	210	Target Neighborhood Hits	382	Shared Neighborhood Hits	11
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

SPT6H_HUMAN
θ value	6.88961 (rank : 191)	NC score	0.011351 (rank : 182)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SPT6H_MOUSE
θ value	6.88961 (rank : 192)	NC score	0.010898 (rank : 185)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

STAM1_MOUSE
θ value	6.88961 (rank : 193)	NC score	0.002540 (rank : 209)
Query Neighborhood Hits	210	Target Neighborhood Hits	273	Shared Neighborhood Hits	8
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAT2_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.003036 (rank : 208)
Query Neighborhood Hits	210	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

ZBT16_HUMAN
θ value	6.88961 (rank : 195)	NC score	-0.006141 (rank : 223)
Query Neighborhood Hits	210	Target Neighborhood Hits	1010	Shared Neighborhood Hits	17
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

BSN_MOUSE
θ value	8.99809 (rank : 196)	NC score	0.037171 (rank : 124)
Query Neighborhood Hits	210	Target Neighborhood Hits	2057	Shared Neighborhood Hits	93
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CECR2_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.022666 (rank : 152)
Query Neighborhood Hits	210	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

DCC_MOUSE
θ value	8.99809 (rank : 198)	NC score	0.006777 (rank : 196)
Query Neighborhood Hits	210	Target Neighborhood Hits	896	Shared Neighborhood Hits	38
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ECM1_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.021328 (rank : 157)
Query Neighborhood Hits	210	Target Neighborhood Hits	182	Shared Neighborhood Hits	23
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

EP300_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.043807 (rank : 115)
Query Neighborhood Hits	210	Target Neighborhood Hits	821	Shared Neighborhood Hits	87
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GAK_HUMAN
θ value	8.99809 (rank : 201)	NC score	-0.002767 (rank : 219)
Query Neighborhood Hits	210	Target Neighborhood Hits	1028	Shared Neighborhood Hits	30
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

HIPK3_MOUSE
θ value	8.99809 (rank : 202)	NC score	-0.003174 (rank : 222)
Query Neighborhood Hits	210	Target Neighborhood Hits	857	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HXC4_HUMAN
θ value	8.99809 (rank : 203)	NC score	-0.002276 (rank : 216)
Query Neighborhood Hits	210	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	P09017	Gene names	HOXC4, HOX3E
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3E) (CP19).

HXC4_MOUSE
θ value	8.99809 (rank : 204)	NC score	-0.002273 (rank : 215)
Query Neighborhood Hits	210	Target Neighborhood Hits	365	Shared Neighborhood Hits	7
SwissProt Accessions	Q08624	Gene names	Hoxc4, Hox-3.5, Hoxc-4
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3.5).

IASPP_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.015171 (rank : 173)
Query Neighborhood Hits	210	Target Neighborhood Hits	688	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

K0056_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.009561 (rank : 188)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

MDC1_HUMAN
θ value	8.99809 (rank : 207)	NC score	0.032903 (rank : 131)
Query Neighborhood Hits	210	Target Neighborhood Hits	1446	Shared Neighborhood Hits	67
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NACAM_MOUSE
θ value	8.99809 (rank : 208)	NC score	0.044115 (rank : 114)
Query Neighborhood Hits	210	Target Neighborhood Hits	1866	Shared Neighborhood Hits	88
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PCD16_HUMAN
θ value	8.99809 (rank : 209)	NC score	-0.001061 (rank : 214)
Query Neighborhood Hits	210	Target Neighborhood Hits	245	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

SETX_HUMAN
θ value	8.99809 (rank : 210)	NC score	0.007661 (rank : 191)
Query Neighborhood Hits	210	Target Neighborhood Hits	368	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

CJ078_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.051537 (rank : 109)
Query Neighborhood Hits	210	Target Neighborhood Hits	559	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN092_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.207001 (rank : 78)
Query Neighborhood Hits	210	Target Neighborhood Hits	143	Shared Neighborhood Hits	69
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.204382 (rank : 79)
Query Neighborhood Hits	210	Target Neighborhood Hits	206	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

GAK1_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.052323 (rank : 108)
Query Neighborhood Hits	210	Target Neighborhood Hits	268	Shared Neighborhood Hits	31
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GCX1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.152700 (rank : 82)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	62
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.051288 (rank : 110)
Query Neighborhood Hits	210	Target Neighborhood Hits	330	Shared Neighborhood Hits	59
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP2_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.056896 (rank : 98)
Query Neighborhood Hits	210	Target Neighborhood Hits	347	Shared Neighborhood Hits	54
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.058922 (rank : 95)
Query Neighborhood Hits	210	Target Neighborhood Hits	460	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RERE_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.057475 (rank : 97)
Query Neighborhood Hits	210	Target Neighborhood Hits	785	Shared Neighborhood Hits	87
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TFAM_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.265786 (rank : 76)
Query Neighborhood Hits	210	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

TOX_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.182800 (rank : 81)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	59
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.183831 (rank : 80)
Query Neighborhood Hits	210	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

WASIP_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.055449 (rank : 102)
Query Neighborhood Hits	210	Target Neighborhood Hits	458	Shared Neighborhood Hits	66
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

Hits sorted by NC score

SOX9_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	210	Target Neighborhood Hits	210	Shared Neighborhood Hits	210
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_MOUSE
NC score	0.992769 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	210	Target Neighborhood Hits	188	Shared Neighborhood Hits	148
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX10_MOUSE
NC score	0.977116 (rank : 3)	θ value	1.25199e-126 (rank : 4)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	80
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX8_MOUSE
NC score	0.976627 (rank : 4)	θ value	2.37764e-101 (rank : 5)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	77
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX10_HUMAN
NC score	0.976263 (rank : 5)	θ value	1.25199e-126 (rank : 3)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	80
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX8_HUMAN
NC score	0.976107 (rank : 6)	θ value	1.65039e-94 (rank : 6)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX12_MOUSE
NC score	0.934212 (rank : 7)	θ value	1.92365e-26 (rank : 20)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX12_HUMAN
NC score	0.931695 (rank : 8)	θ value	1.92365e-26 (rank : 19)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX11_HUMAN
NC score	0.918202 (rank : 9)	θ value	2.77775e-25 (rank : 26)
Query Neighborhood Hits	210	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX21_MOUSE
NC score	0.918063 (rank : 10)	θ value	1.33217e-27 (rank : 11)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX21_HUMAN
NC score	0.918045 (rank : 11)	θ value	1.33217e-27 (rank : 10)
Query Neighborhood Hits	210	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX11_MOUSE
NC score	0.915878 (rank : 12)	θ value	2.77775e-25 (rank : 27)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	80
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX4_HUMAN
NC score	0.915635 (rank : 13)	θ value	4.28545e-26 (rank : 24)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	81
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX15_MOUSE
NC score	0.915325 (rank : 14)	θ value	1.05554e-24 (rank : 28)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX18_MOUSE
NC score	0.913286 (rank : 15)	θ value	1.33217e-27 (rank : 9)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	79
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX18_HUMAN
NC score	0.913211 (rank : 16)	θ value	2.27234e-27 (rank : 13)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	79
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX4_MOUSE
NC score	0.912989 (rank : 17)	θ value	2.51237e-26 (rank : 22)
Query Neighborhood Hits	210	Target Neighborhood Hits	108	Shared Neighborhood Hits	79
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX15_HUMAN
NC score	0.912652 (rank : 18)	θ value	1.24688e-25 (rank : 25)
Query Neighborhood Hits	210	Target Neighborhood Hits	134	Shared Neighborhood Hits	80
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX17_HUMAN
NC score	0.908700 (rank : 19)	θ value	4.89182e-30 (rank : 8)
Query Neighborhood Hits	210	Target Neighborhood Hits	108	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX14_MOUSE
NC score	0.908293 (rank : 20)	θ value	2.96777e-27 (rank : 15)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_HUMAN
NC score	0.908287 (rank : 21)	θ value	2.96777e-27 (rank : 14)
Query Neighborhood Hits	210	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX1_HUMAN
NC score	0.906084 (rank : 22)	θ value	4.28545e-26 (rank : 23)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SRY_HUMAN
NC score	0.905365 (rank : 23)	θ value	1.02238e-19 (rank : 38)
Query Neighborhood Hits	210	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX1_MOUSE
NC score	0.905010 (rank : 24)	θ value	1.92365e-26 (rank : 21)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX3_MOUSE
NC score	0.902342 (rank : 25)	θ value	2.35151e-24 (rank : 29)
Query Neighborhood Hits	210	Target Neighborhood Hits	101	Shared Neighborhood Hits	80
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX2_HUMAN
NC score	0.899248 (rank : 26)	θ value	8.63488e-27 (rank : 17)
Query Neighborhood Hits	210	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
NC score	0.898896 (rank : 27)	θ value	8.63488e-27 (rank : 18)
Query Neighborhood Hits	210	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX7_MOUSE
NC score	0.898122 (rank : 28)	θ value	1.33217e-27 (rank : 12)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	77
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX17_MOUSE
NC score	0.897949 (rank : 29)	θ value	3.74554e-30 (rank : 7)
Query Neighborhood Hits	210	Target Neighborhood Hits	223	Shared Neighborhood Hits	88
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX3_HUMAN
NC score	0.897651 (rank : 30)	θ value	3.07116e-24 (rank : 30)
Query Neighborhood Hits	210	Target Neighborhood Hits	109	Shared Neighborhood Hits	80
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SRY_MOUSE
NC score	0.892944 (rank : 31)	θ value	1.5242e-23 (rank : 31)
Query Neighborhood Hits	210	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX7_HUMAN
NC score	0.892600 (rank : 32)	θ value	6.61148e-27 (rank : 16)
Query Neighborhood Hits	210	Target Neighborhood Hits	140	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX5_MOUSE
NC score	0.817362 (rank : 33)	θ value	6.40375e-22 (rank : 33)
Query Neighborhood Hits	210	Target Neighborhood Hits	196	Shared Neighborhood Hits	88
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_HUMAN
NC score	0.815461 (rank : 34)	θ value	6.40375e-22 (rank : 32)
Query Neighborhood Hits	210	Target Neighborhood Hits	219	Shared Neighborhood Hits	90
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX6_HUMAN
NC score	0.796561 (rank : 35)	θ value	3.51386e-20 (rank : 36)
Query Neighborhood Hits	210	Target Neighborhood Hits	332	Shared Neighborhood Hits	90
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
NC score	0.795839 (rank : 36)	θ value	3.51386e-20 (rank : 37)
Query Neighborhood Hits	210	Target Neighborhood Hits	341	Shared Neighborhood Hits	90
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SOX13_MOUSE
NC score	0.794952 (rank : 37)	θ value	5.42112e-21 (rank : 35)
Query Neighborhood Hits	210	Target Neighborhood Hits	495	Shared Neighborhood Hits	99
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX13_HUMAN
NC score	0.791993 (rank : 38)	θ value	5.42112e-21 (rank : 34)
Query Neighborhood Hits	210	Target Neighborhood Hits	464	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX30_MOUSE
NC score	0.791960 (rank : 39)	θ value	5.25075e-16 (rank : 40)
Query Neighborhood Hits	210	Target Neighborhood Hits	374	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SOX30_HUMAN
NC score	0.788444 (rank : 40)	θ value	6.20254e-17 (rank : 39)
Query Neighborhood Hits	210	Target Neighborhood Hits	305	Shared Neighborhood Hits	96
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

HBP1_MOUSE
NC score	0.660060 (rank : 41)	θ value	2.61198e-07 (rank : 50)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_HUMAN
NC score	0.659900 (rank : 42)	θ value	2.61198e-07 (rank : 49)
Query Neighborhood Hits	210	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

CIC_MOUSE
NC score	0.651222 (rank : 43)	θ value	7.84624e-12 (rank : 42)
Query Neighborhood Hits	210	Target Neighborhood Hits	742	Shared Neighborhood Hits	135
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BBX_HUMAN
NC score	0.628229 (rank : 44)	θ value	3.41135e-07 (rank : 51)
Query Neighborhood Hits	210	Target Neighborhood Hits	167	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BBX_MOUSE
NC score	0.619081 (rank : 45)	θ value	7.59969e-07 (rank : 54)
Query Neighborhood Hits	210	Target Neighborhood Hits	152	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

CIC_HUMAN
NC score	0.615675 (rank : 46)	θ value	1.2105e-12 (rank : 41)
Query Neighborhood Hits	210	Target Neighborhood Hits	992	Shared Neighborhood Hits	142
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TCF7_HUMAN
NC score	0.614737 (rank : 47)	θ value	9.92553e-07 (rank : 55)
Query Neighborhood Hits	210	Target Neighborhood Hits	186	Shared Neighborhood Hits	80
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

HMGB3_HUMAN
NC score	0.610447 (rank : 48)	θ value	8.11959e-09 (rank : 44)
Query Neighborhood Hits	210	Target Neighborhood Hits	86	Shared Neighborhood Hits	68
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_MOUSE
NC score	0.600446 (rank : 49)	θ value	5.26297e-08 (rank : 46)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

TCF7_MOUSE
NC score	0.580325 (rank : 50)	θ value	1.69304e-06 (rank : 56)
Query Neighborhood Hits	210	Target Neighborhood Hits	277	Shared Neighborhood Hits	78
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

SSRP1_MOUSE
NC score	0.574110 (rank : 51)	θ value	1.17247e-07 (rank : 48)
Query Neighborhood Hits	210	Target Neighborhood Hits	193	Shared Neighborhood Hits	81
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

TF7L2_MOUSE
NC score	0.573902 (rank : 52)	θ value	4.45536e-07 (rank : 53)
Query Neighborhood Hits	210	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TF7L2_HUMAN
NC score	0.571892 (rank : 53)	θ value	4.45536e-07 (rank : 52)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

SSRP1_HUMAN
NC score	0.567753 (rank : 54)	θ value	8.97725e-08 (rank : 47)
Query Neighborhood Hits	210	Target Neighborhood Hits	187	Shared Neighborhood Hits	81
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

TF7L1_MOUSE
NC score	0.564019 (rank : 55)	θ value	4.76016e-09 (rank : 43)
Query Neighborhood Hits	210	Target Neighborhood Hits	131	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

TF7L1_HUMAN
NC score	0.561535 (rank : 56)	θ value	2.36244e-08 (rank : 45)
Query Neighborhood Hits	210	Target Neighborhood Hits	129	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

LEF1_HUMAN
NC score	0.560619 (rank : 57)	θ value	1.43324e-05 (rank : 61)
Query Neighborhood Hits	210	Target Neighborhood Hits	150	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
NC score	0.559813 (rank : 58)	θ value	1.43324e-05 (rank : 62)
Query Neighborhood Hits	210	Target Neighborhood Hits	161	Shared Neighborhood Hits	79
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

HMGB2_HUMAN
NC score	0.551423 (rank : 59)	θ value	4.92598e-06 (rank : 57)
Query Neighborhood Hits	210	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_MOUSE
NC score	0.539782 (rank : 60)	θ value	1.09739e-05 (rank : 58)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	76
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HM20B_HUMAN
NC score	0.522775 (rank : 61)	θ value	0.000602161 (rank : 66)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

HMGB1_MOUSE
NC score	0.513210 (rank : 62)	θ value	1.43324e-05 (rank : 60)
Query Neighborhood Hits	210	Target Neighborhood Hits	123	Shared Neighborhood Hits	76
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_HUMAN
NC score	0.513132 (rank : 63)	θ value	1.43324e-05 (rank : 59)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	76
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HM20B_MOUSE
NC score	0.502430 (rank : 64)	θ value	0.00228821 (rank : 68)
Query Neighborhood Hits	210	Target Neighborhood Hits	122	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

HMG1X_HUMAN
NC score	0.481525 (rank : 65)	θ value	3.19293e-05 (rank : 63)
Query Neighborhood Hits	210	Target Neighborhood Hits	97	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

UBF1_HUMAN
NC score	0.462258 (rank : 66)	θ value	0.00020696 (rank : 64)
Query Neighborhood Hits	210	Target Neighborhood Hits	415	Shared Neighborhood Hits	83
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBF1_MOUSE
NC score	0.454919 (rank : 67)	θ value	0.000270298 (rank : 65)
Query Neighborhood Hits	210	Target Neighborhood Hits	419	Shared Neighborhood Hits	84
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

HM2L1_HUMAN
NC score	0.443855 (rank : 68)	θ value	0.0148317 (rank : 74)
Query Neighborhood Hits	210	Target Neighborhood Hits	130	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

HM20A_HUMAN
NC score	0.429847 (rank : 69)	θ value	0.00509761 (rank : 70)
Query Neighborhood Hits	210	Target Neighborhood Hits	343	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
NC score	0.428283 (rank : 70)	θ value	0.00509761 (rank : 71)
Query Neighborhood Hits	210	Target Neighborhood Hits	348	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

TFAM_MOUSE
NC score	0.331033 (rank : 71)	θ value	0.47712 (rank : 109)
Query Neighborhood Hits	210	Target Neighborhood Hits	93	Shared Neighborhood Hits	73
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

SMCE1_HUMAN
NC score	0.322060 (rank : 72)	θ value	0.0961366 (rank : 88)
Query Neighborhood Hits	210	Target Neighborhood Hits	272	Shared Neighborhood Hits	67
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
NC score	0.303004 (rank : 73)	θ value	0.0961366 (rank : 89)
Query Neighborhood Hits	210	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

SP100_HUMAN
NC score	0.292783 (rank : 74)	θ value	0.0113563 (rank : 73)
Query Neighborhood Hits	210	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

PB1_HUMAN
NC score	0.284892 (rank : 75)	θ value	0.00665767 (rank : 72)
Query Neighborhood Hits	210	Target Neighborhood Hits	261	Shared Neighborhood Hits	91
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TFAM_HUMAN
NC score	0.265786 (rank : 76)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	210	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

PMS1_HUMAN
NC score	0.246203 (rank : 77)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	210	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

CN092_HUMAN
NC score	0.207001 (rank : 78)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	210	Target Neighborhood Hits	143	Shared Neighborhood Hits	69
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
NC score	0.204382 (rank : 79)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	210	Target Neighborhood Hits	206	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

TOX_MOUSE
NC score	0.183831 (rank : 80)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	210	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_HUMAN
NC score	0.182800 (rank : 81)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	210	Target Neighborhood Hits	106	Shared Neighborhood Hits	59
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

GCX1_HUMAN
NC score	0.152700 (rank : 82)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	210	Target Neighborhood Hits	132	Shared Neighborhood Hits	62
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

RPB1_MOUSE
NC score	0.066477 (rank : 83)	θ value	0.0330416 (rank : 83)
Query Neighborhood Hits	210	Target Neighborhood Hits	363	Shared Neighborhood Hits	48
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.066185 (rank : 84)	θ value	0.0330416 (rank : 82)
Query Neighborhood Hits	210	Target Neighborhood Hits	362	Shared Neighborhood Hits	47
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ARI1A_HUMAN
NC score	0.065647 (rank : 85)	θ value	0.365318 (rank : 99)
Query Neighborhood Hits	210	Target Neighborhood Hits	787	Shared Neighborhood Hits	84
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

R3HD2_MOUSE
NC score	0.064251 (rank : 86)	θ value	0.0330416 (rank : 81)
Query Neighborhood Hits	210	Target Neighborhood Hits	397	Shared Neighborhood Hits	44
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

GAK5_HUMAN
NC score	0.062919 (rank : 87)	θ value	0.0193708 (rank : 75)
Query Neighborhood Hits	210	Target Neighborhood Hits	429	Shared Neighborhood Hits	41
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
NC score	0.062473 (rank : 88)	θ value	0.0252991 (rank : 77)
Query Neighborhood Hits	210	Target Neighborhood Hits	374	Shared Neighborhood Hits	38
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.062354 (rank : 89)	θ value	0.0252991 (rank : 78)
Query Neighborhood Hits	210	Target Neighborhood Hits	415	Shared Neighborhood Hits	40
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.062154 (rank : 90)	θ value	0.0252991 (rank : 76)
Query Neighborhood Hits	210	Target Neighborhood Hits	409	Shared Neighborhood Hits	39
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.061362 (rank : 91)	θ value	0.0330416 (rank : 80)
Query Neighborhood Hits	210	Target Neighborhood Hits	406	Shared Neighborhood Hits	37
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

BAT2_HUMAN
NC score	0.060912 (rank : 92)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	210	Target Neighborhood Hits	931	Shared Neighborhood Hits	86
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RERE_HUMAN
NC score	0.059990 (rank : 93)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	210	Target Neighborhood Hits	779	Shared Neighborhood Hits	92
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

GAK6_HUMAN
NC score	0.059877 (rank : 94)	θ value	0.0252991 (rank : 79)
Query Neighborhood Hits	210	Target Neighborhood Hits	392	Shared Neighborhood Hits	38
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PRR12_HUMAN
NC score	0.058922 (rank : 95)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	210	Target Neighborhood Hits	460	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

GAK10_HUMAN
NC score	0.057655 (rank : 96)	θ value	0.47712 (rank : 107)
Query Neighborhood Hits	210	Target Neighborhood Hits	289	Shared Neighborhood Hits	31
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RERE_MOUSE
NC score	0.057475 (rank : 97)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	210	Target Neighborhood Hits	785	Shared Neighborhood Hits	87
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

PRP2_MOUSE
NC score	0.056896 (rank : 98)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	210	Target Neighborhood Hits	347	Shared Neighborhood Hits	54
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

ATN1_HUMAN
NC score	0.056246 (rank : 99)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	210	Target Neighborhood Hits	676	Shared Neighborhood Hits	73
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ATX2L_HUMAN
NC score	0.056129 (rank : 100)	θ value	0.365318 (rank : 100)
Query Neighborhood Hits	210	Target Neighborhood Hits	443	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BRD4_HUMAN
NC score	0.055821 (rank : 101)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	210	Target Neighborhood Hits	851	Shared Neighborhood Hits	84
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

WASIP_HUMAN
NC score	0.055449 (rank : 102)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	210	Target Neighborhood Hits	458	Shared Neighborhood Hits	66
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CD2_HUMAN
NC score	0.054881 (rank : 103)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	210	Target Neighborhood Hits	504	Shared Neighborhood Hits	49
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

TARSH_HUMAN
NC score	0.054306 (rank : 104)	θ value	0.0330416 (rank : 84)
Query Neighborhood Hits	210	Target Neighborhood Hits	768	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

BAT2_MOUSE
NC score	0.053874 (rank : 105)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	210	Target Neighborhood Hits	947	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CRTC1_HUMAN
NC score	0.053512 (rank : 106)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	210	Target Neighborhood Hits	319	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

LPP_HUMAN
NC score	0.052796 (rank : 107)	θ value	0.00228821 (rank : 69)
Query Neighborhood Hits	210	Target Neighborhood Hits	775	Shared Neighborhood Hits	49
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

GAK1_HUMAN
NC score	0.052323 (rank : 108)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	210	Target Neighborhood Hits	268	Shared Neighborhood Hits	31
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CJ078_MOUSE
NC score	0.051537 (rank : 109)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	210	Target Neighborhood Hits	559	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

PRB4S_HUMAN
NC score	0.051288 (rank : 110)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	210	Target Neighborhood Hits	330	Shared Neighborhood Hits	59
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

ATX2L_MOUSE
NC score	0.050868 (rank : 111)	θ value	0.365318 (rank : 101)
Query Neighborhood Hits	210	Target Neighborhood Hits	401	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

NCOA6_HUMAN
NC score	0.044794 (rank : 112)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	210	Target Neighborhood Hits	1202	Shared Neighborhood Hits	89
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BTBDC_HUMAN
NC score	0.044317 (rank : 113)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	210	Target Neighborhood Hits	248	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

NACAM_MOUSE
NC score	0.044115 (rank : 114)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	210	Target Neighborhood Hits	1866	Shared Neighborhood Hits	88
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

EP300_HUMAN
NC score	0.043807 (rank : 115)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	210	Target Neighborhood Hits	821	Shared Neighborhood Hits	87
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

PCLO_MOUSE
NC score	0.043512 (rank : 116)	θ value	0.0961366 (rank : 87)
Query Neighborhood Hits	210	Target Neighborhood Hits	2275	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RGS3_MOUSE
NC score	0.042265 (rank : 117)	θ value	0.00134147 (rank : 67)
Query Neighborhood Hits	210	Target Neighborhood Hits	1621	Shared Neighborhood Hits	81
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PCLO_HUMAN
NC score	0.041543 (rank : 118)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	210	Target Neighborhood Hits	2046	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

NCOA6_MOUSE
NC score	0.040924 (rank : 119)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	210	Target Neighborhood Hits	1076	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PRRT3_HUMAN
NC score	0.040390 (rank : 120)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	210	Target Neighborhood Hits	998	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ENAM_HUMAN
NC score	0.039830 (rank : 121)	θ value	0.47712 (rank : 106)
Query Neighborhood Hits	210	Target Neighborhood Hits	227	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

AL2S4_MOUSE
NC score	0.039111 (rank : 122)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	210	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

TRI66_HUMAN
NC score	0.037623 (rank : 123)	θ value	0.163984 (rank : 93)
Query Neighborhood Hits	210	Target Neighborhood Hits	479	Shared Neighborhood Hits	51
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BSN_MOUSE
NC score	0.037171 (rank : 124)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	210	Target Neighborhood Hits	2057	Shared Neighborhood Hits	93
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MLL3_HUMAN
NC score	0.036471 (rank : 125)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	210	Target Neighborhood Hits	1644	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

GPS2_HUMAN
NC score	0.034934 (rank : 126)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	210	Target Neighborhood Hits	459	Shared Neighborhood Hits	32
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

TFEB_HUMAN
NC score	0.034804 (rank : 127)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
NC score	0.034379 (rank : 128)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	210	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

GRIN1_MOUSE
NC score	0.033669 (rank : 129)	θ value	0.279714 (rank : 97)
Query Neighborhood Hits	210	Target Neighborhood Hits	337	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

LIPS_HUMAN
NC score	0.033613 (rank : 130)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	210	Target Neighborhood Hits	314	Shared Neighborhood Hits	34
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MDC1_HUMAN
NC score	0.032903 (rank : 131)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	210	Target Neighborhood Hits	1446	Shared Neighborhood Hits	67
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

GTSE1_MOUSE
NC score	0.032551 (rank : 132)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	210	Target Neighborhood Hits	245	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

EST1A_MOUSE
NC score	0.030877 (rank : 133)	θ value	1.06291 (rank : 119)
Query Neighborhood Hits	210	Target Neighborhood Hits	138	Shared Neighborhood Hits	9
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

FBX34_MOUSE
NC score	0.030444 (rank : 134)	θ value	0.125558 (rank : 90)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

NIPBL_HUMAN
NC score	0.030418 (rank : 135)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	210	Target Neighborhood Hits	1311	Shared Neighborhood Hits	64
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
NC score	0.030153 (rank : 136)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	210	Target Neighborhood Hits	1041	Shared Neighborhood Hits	61
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PI5PA_HUMAN
NC score	0.030087 (rank : 137)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	210	Target Neighborhood Hits	749	Shared Neighborhood Hits	55
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

LCP2_HUMAN
NC score	0.029822 (rank : 138)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	210	Target Neighborhood Hits	531	Shared Neighborhood Hits	47
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

JHD2C_MOUSE
NC score	0.029534 (rank : 139)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	210	Target Neighborhood Hits	297	Shared Neighborhood Hits	25
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

TRI66_MOUSE
NC score	0.029428 (rank : 140)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	210	Target Neighborhood Hits	491	Shared Neighborhood Hits	44
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SYNJ1_MOUSE
NC score	0.029200 (rank : 141)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	210	Target Neighborhood Hits	516	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

EST1A_HUMAN
NC score	0.028271 (rank : 142)	θ value	0.365318 (rank : 102)
Query Neighborhood Hits	210	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q86US8, O94837, Q86VH6, Q9UF60	Gene names	EST1A, C17orf31, KIAA0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) (hSmg5/7a).

PKCB1_HUMAN
NC score	0.027406 (rank : 143)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	210	Target Neighborhood Hits	488	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

MAML3_HUMAN
NC score	0.026468 (rank : 144)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	210	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

FA47A_HUMAN
NC score	0.026176 (rank : 145)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	210	Target Neighborhood Hits	451	Shared Neighborhood Hits	46
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

ALMS1_HUMAN
NC score	0.025669 (rank : 146)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	210	Target Neighborhood Hits	356	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

JHD2C_HUMAN
NC score	0.024329 (rank : 147)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	210	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

NFH_MOUSE
NC score	0.023839 (rank : 148)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	210	Target Neighborhood Hits	2247	Shared Neighborhood Hits	83
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GPTC8_HUMAN
NC score	0.023755 (rank : 149)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	210	Target Neighborhood Hits	366	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

CABIN_HUMAN
NC score	0.022801 (rank : 150)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	210	Target Neighborhood Hits	490	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

HELZ_HUMAN
NC score	0.022772 (rank : 151)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	210	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

CECR2_HUMAN
NC score	0.022666 (rank : 152)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	210	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

TXND2_HUMAN
NC score	0.022601 (rank : 153)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	210	Target Neighborhood Hits	793	Shared Neighborhood Hits	41
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

LPP_MOUSE
NC score	0.022541 (rank : 154)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	210	Target Neighborhood Hits	247	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

PHC2_HUMAN
NC score	0.021849 (rank : 155)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	210	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

TULP4_HUMAN
NC score	0.021538 (rank : 156)	θ value	0.21417 (rank : 95)
Query Neighborhood Hits	210	Target Neighborhood Hits	426	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ECM1_HUMAN
NC score	0.021328 (rank : 157)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	210	Target Neighborhood Hits	182	Shared Neighborhood Hits	23
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

APBB2_MOUSE
NC score	0.021122 (rank : 158)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	210	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

BTBD7_MOUSE
NC score	0.020680 (rank : 159)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	210	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

SH22A_MOUSE
NC score	0.020386 (rank : 160)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	210	Target Neighborhood Hits	179	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

K1683_HUMAN
NC score	0.020275 (rank : 161)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	210	Target Neighborhood Hits	240	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

AIRE_MOUSE
NC score	0.019662 (rank : 162)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	210	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

CEL_HUMAN
NC score	0.019548 (rank : 163)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	210	Target Neighborhood Hits	896	Shared Neighborhood Hits	50
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

PKNX2_MOUSE
NC score	0.019494 (rank : 164)	θ value	0.21417 (rank : 94)
Query Neighborhood Hits	210	Target Neighborhood Hits	197	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

IWS1_MOUSE
NC score	0.018143 (rank : 165)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	210	Target Neighborhood Hits	1258	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RC3H1_HUMAN
NC score	0.016993 (rank : 166)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	210	Target Neighborhood Hits	433	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

PF21A_MOUSE
NC score	0.016521 (rank : 167)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	210	Target Neighborhood Hits	285	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

SMAL1_HUMAN
NC score	0.016368 (rank : 168)	θ value	0.365318 (rank : 103)
Query Neighborhood Hits	210	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

TENS4_HUMAN
NC score	0.016330 (rank : 169)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	210	Target Neighborhood Hits	214	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

PF21A_HUMAN
NC score	0.015555 (rank : 170)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	210	Target Neighborhood Hits	303	Shared Neighborhood Hits	17
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

MYO15_MOUSE
NC score	0.015540 (rank : 171)	θ value	0.0736092 (rank : 85)
Query Neighborhood Hits	210	Target Neighborhood Hits	467	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PKNX2_HUMAN
NC score	0.015435 (rank : 172)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	210	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

IASPP_HUMAN
NC score	0.015171 (rank : 173)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	210	Target Neighborhood Hits	688	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

APBB2_HUMAN
NC score	0.014526 (rank : 174)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	210	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

ECM1_MOUSE
NC score	0.014071 (rank : 175)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	210	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

ANK2_HUMAN
NC score	0.013767 (rank : 176)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	210	Target Neighborhood Hits	1615	Shared Neighborhood Hits	76
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MYCD_MOUSE
NC score	0.013566 (rank : 177)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	210	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

SH2D3_HUMAN
NC score	0.013144 (rank : 178)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	210	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

ZN414_MOUSE
NC score	0.011899 (rank : 179)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	210	Target Neighborhood Hits	473	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

NFAC1_HUMAN
NC score	0.011499 (rank : 180)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	210	Target Neighborhood Hits	312	Shared Neighborhood Hits	36
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

MYCL1_HUMAN
NC score	0.011470 (rank : 181)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	210	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

SPT6H_HUMAN
NC score	0.011351 (rank : 182)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

TACC2_HUMAN
NC score	0.011164 (rank : 183)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	210	Target Neighborhood Hits	856	Shared Neighborhood Hits	28
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

ILF3_HUMAN
NC score	0.011113 (rank : 184)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	210	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

SPT6H_MOUSE
NC score	0.010898 (rank : 185)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	210	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

PRC1_HUMAN
NC score	0.010756 (rank : 186)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	210	Target Neighborhood Hits	328	Shared Neighborhood Hits	10
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

PRC1_MOUSE
NC score	0.009701 (rank : 187)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	210	Target Neighborhood Hits	382	Shared Neighborhood Hits	11
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

K0056_HUMAN
NC score	0.009561 (rank : 188)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	210	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

P2RX2_HUMAN
NC score	0.009327 (rank : 189)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	210	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

ANR15_HUMAN
NC score	0.009289 (rank : 190)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	210	Target Neighborhood Hits	478	Shared Neighborhood Hits	13
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

SETX_HUMAN
NC score	0.007661 (rank : 191)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	210	Target Neighborhood Hits	368	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

NCOA2_HUMAN
NC score	0.007648 (rank : 192)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	210	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

ARHGB_HUMAN
NC score	0.007549 (rank : 193)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	210	Target Neighborhood Hits	375	Shared Neighborhood Hits	19
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ETV4_MOUSE
NC score	0.007456 (rank : 194)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	210	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

PTN12_MOUSE
NC score	0.007019 (rank : 195)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	210	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

DCC_MOUSE
NC score	0.006777 (rank : 196)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	210	Target Neighborhood Hits	896	Shared Neighborhood Hits	38
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

AFAD_HUMAN
NC score	0.006572 (rank : 197)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	210	Target Neighborhood Hits	689	Shared Neighborhood Hits	25
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CAC1G_HUMAN
NC score	0.006309 (rank : 198)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	210	Target Neighborhood Hits	587	Shared Neighborhood Hits	33
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

EHMT2_MOUSE
NC score	0.006088 (rank : 199)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	210	Target Neighborhood Hits	750	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ZN516_MOUSE
NC score	0.004831 (rank : 200)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	210	Target Neighborhood Hits	1197	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

OBSCN_HUMAN
NC score	0.004012 (rank : 201)	θ value	0.0736092 (rank : 86)
Query Neighborhood Hits	210	Target Neighborhood Hits	1931	Shared Neighborhood Hits	56
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ADA12_MOUSE
NC score	0.003936 (rank : 202)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	210	Target Neighborhood Hits	474	Shared Neighborhood Hits	21
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

RPKL1_MOUSE
NC score	0.003914 (rank : 203)	θ value	0.163984 (rank : 92)
Query Neighborhood Hits	210	Target Neighborhood Hits	704	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

INVS_MOUSE
NC score	0.003817 (rank : 204)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	210	Target Neighborhood Hits	609	Shared Neighborhood Hits	30
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

KCNQ5_HUMAN
NC score	0.003338 (rank : 205)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	210	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

BOC_HUMAN
NC score	0.003251 (rank : 206)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	210	Target Neighborhood Hits	543	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

SPEG_MOUSE
NC score	0.003204 (rank : 207)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	210	Target Neighborhood Hits	1959	Shared Neighborhood Hits	75
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

STAT2_HUMAN
NC score	0.003036 (rank : 208)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	210	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAM1_MOUSE
NC score	0.002540 (rank : 209)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	210	Target Neighborhood Hits	273	Shared Neighborhood Hits	8
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CP3AB_MOUSE
NC score	0.002353 (rank : 210)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	210	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q64459	Gene names	Cyp3a11, Cyp3a-11
Domain Architecture
Description	Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11) (P-450IIIAM1) (P- 450UT).

CP341_MOUSE
NC score	0.001747 (rank : 211)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	210	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JMA7	Gene names	Cyp3a41
Domain Architecture
Description	Cytochrome P450 3A41 (EC 1.14.14.1).

NOTC2_MOUSE
NC score	0.001333 (rank : 212)	θ value	0.47712 (rank : 108)
Query Neighborhood Hits	210	Target Neighborhood Hits	1069	Shared Neighborhood Hits	32
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ZN217_HUMAN
NC score	0.000456 (rank : 213)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	210	Target Neighborhood Hits	905	Shared Neighborhood Hits	21
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

PCD16_HUMAN
NC score	-0.001061 (rank : 214)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	210	Target Neighborhood Hits	245	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

HXC4_MOUSE
NC score	-0.002273 (rank : 215)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	210	Target Neighborhood Hits	365	Shared Neighborhood Hits	7
SwissProt Accessions	Q08624	Gene names	Hoxc4, Hox-3.5, Hoxc-4
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3.5).

HXC4_HUMAN
NC score	-0.002276 (rank : 216)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	210	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	P09017	Gene names	HOXC4, HOX3E
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3E) (CP19).

GLI3_HUMAN
NC score	-0.002561 (rank : 217)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	210	Target Neighborhood Hits	871	Shared Neighborhood Hits	21
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

CAMKV_HUMAN
NC score	-0.002717 (rank : 218)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	210	Target Neighborhood Hits	1084	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

GAK_HUMAN
NC score	-0.002767 (rank : 219)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	210	Target Neighborhood Hits	1028	Shared Neighborhood Hits	30
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

MRCKB_HUMAN
NC score	-0.002807 (rank : 220)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	210	Target Neighborhood Hits	2239	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

K0999_MOUSE
NC score	-0.002944 (rank : 221)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	210	Target Neighborhood Hits	931	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

HIPK3_MOUSE
NC score	-0.003174 (rank : 222)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	210	Target Neighborhood Hits	857	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

ZBT16_HUMAN
NC score	-0.006141 (rank : 223)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	210	Target Neighborhood Hits	1010	Shared Neighborhood Hits	17
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).