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Network neighborhood for query Sequence : MYCL1_HUMAN

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MYCL1_HUMAN
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MYCL1_HUMAN
θ value	7.23842e-175 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	146
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
θ value	4.12933e-154 (rank : 2)	NC score	0.977155 (rank : 2)
Query Neighborhood Hits	146	Target Neighborhood Hits	123	Shared Neighborhood Hits	82
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
θ value	1.13238e-127 (rank : 3)	NC score	0.944511 (rank : 3)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYC_HUMAN
θ value	1.16434e-31 (rank : 4)	NC score	0.784758 (rank : 4)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_MOUSE
θ value	3.17079e-29 (rank : 5)	NC score	0.784725 (rank : 5)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCN_MOUSE
θ value	2.27234e-27 (rank : 6)	NC score	0.783242 (rank : 6)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
θ value	1.24688e-25 (rank : 7)	NC score	0.778661 (rank : 7)
Query Neighborhood Hits	146	Target Neighborhood Hits	127	Shared Neighborhood Hits	58
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
θ value	3.51386e-20 (rank : 8)	NC score	0.748298 (rank : 8)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYCB_MOUSE
θ value	1.29631e-06 (rank : 9)	NC score	0.607657 (rank : 9)
Query Neighborhood Hits	146	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MAX_HUMAN
θ value	4.92598e-06 (rank : 10)	NC score	0.554125 (rank : 10)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
θ value	4.92598e-06 (rank : 11)	NC score	0.550295 (rank : 11)
Query Neighborhood Hits	146	Target Neighborhood Hits	139	Shared Neighborhood Hits	56
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

ARNT_MOUSE
θ value	0.000270298 (rank : 12)	NC score	0.193988 (rank : 37)
Query Neighborhood Hits	146	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MXI1_MOUSE
θ value	0.000461057 (rank : 13)	NC score	0.328885 (rank : 12)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

ARNT_HUMAN
θ value	0.000786445 (rank : 14)	NC score	0.197420 (rank : 36)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	42
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MXI1_HUMAN
θ value	0.00175202 (rank : 15)	NC score	0.317028 (rank : 13)
Query Neighborhood Hits	146	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MNT_HUMAN
θ value	0.00298849 (rank : 16)	NC score	0.271514 (rank : 22)
Query Neighborhood Hits	146	Target Neighborhood Hits	496	Shared Neighborhood Hits	59
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	0.00298849 (rank : 17)	NC score	0.279296 (rank : 20)
Query Neighborhood Hits	146	Target Neighborhood Hits	432	Shared Neighborhood Hits	58
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

ARNT2_HUMAN
θ value	0.00390308 (rank : 18)	NC score	0.181403 (rank : 43)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	0.00390308 (rank : 19)	NC score	0.182085 (rank : 42)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

SRBP1_HUMAN
θ value	0.00390308 (rank : 20)	NC score	0.227652 (rank : 30)
Query Neighborhood Hits	146	Target Neighborhood Hits	225	Shared Neighborhood Hits	51
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MAD4_HUMAN
θ value	0.0252991 (rank : 21)	NC score	0.291756 (rank : 19)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	39
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

SRBP1_MOUSE
θ value	0.0252991 (rank : 22)	NC score	0.213318 (rank : 33)
Query Neighborhood Hits	146	Target Neighborhood Hits	384	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

USF1_HUMAN
θ value	0.0252991 (rank : 23)	NC score	0.298176 (rank : 15)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.0252991 (rank : 24)	NC score	0.300716 (rank : 14)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	47
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

FIGLA_HUMAN
θ value	0.0563607 (rank : 25)	NC score	0.242827 (rank : 25)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

WBS14_HUMAN
θ value	0.0563607 (rank : 26)	NC score	0.160669 (rank : 44)
Query Neighborhood Hits	146	Target Neighborhood Hits	273	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

MAD3_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.295018 (rank : 17)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

TFE3_HUMAN
θ value	0.0961366 (rank : 28)	NC score	0.245003 (rank : 23)
Query Neighborhood Hits	146	Target Neighborhood Hits	190	Shared Neighborhood Hits	49
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

BHLH8_MOUSE
θ value	0.125558 (rank : 29)	NC score	0.200440 (rank : 35)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

REXO1_HUMAN
θ value	0.125558 (rank : 30)	NC score	0.039003 (rank : 123)
Query Neighborhood Hits	146	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

SALL3_HUMAN
θ value	0.125558 (rank : 31)	NC score	0.010405 (rank : 170)
Query Neighborhood Hits	146	Target Neighborhood Hits	1066	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

USF2_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.297245 (rank : 16)
Query Neighborhood Hits	146	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.125558 (rank : 33)	NC score	0.294830 (rank : 18)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	55
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

BHLH8_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.193609 (rank : 38)
Query Neighborhood Hits	146	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MAD4_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.244848 (rank : 24)
Query Neighborhood Hits	146	Target Neighborhood Hits	65	Shared Neighborhood Hits	25
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MINT_HUMAN
θ value	0.163984 (rank : 36)	NC score	0.034168 (rank : 125)
Query Neighborhood Hits	146	Target Neighborhood Hits	1291	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NGN3_HUMAN
θ value	0.163984 (rank : 37)	NC score	0.118015 (rank : 63)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

BAT3_MOUSE
θ value	0.21417 (rank : 38)	NC score	0.039012 (rank : 122)
Query Neighborhood Hits	146	Target Neighborhood Hits	518	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

MLX_HUMAN
θ value	0.21417 (rank : 39)	NC score	0.230778 (rank : 28)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	0.21417 (rank : 40)	NC score	0.232636 (rank : 27)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	40
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

NF2L1_MOUSE
θ value	0.21417 (rank : 41)	NC score	0.043857 (rank : 118)
Query Neighborhood Hits	146	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

FIGLA_MOUSE
θ value	0.279714 (rank : 42)	NC score	0.235450 (rank : 26)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

TWST2_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.147307 (rank : 52)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
θ value	0.279714 (rank : 44)	NC score	0.147329 (rank : 51)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

MAD3_MOUSE
θ value	0.365318 (rank : 45)	NC score	0.277945 (rank : 21)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

SRBP2_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.228897 (rank : 29)
Query Neighborhood Hits	146	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

TBCD2_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.040966 (rank : 119)
Query Neighborhood Hits	146	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

APS_HUMAN
θ value	0.47712 (rank : 48)	NC score	0.025411 (rank : 133)
Query Neighborhood Hits	146	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

BHLH3_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.111033 (rank : 64)
Query Neighborhood Hits	146	Target Neighborhood Hits	106	Shared Neighborhood Hits	39
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.107032 (rank : 65)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

KI67_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.044622 (rank : 117)
Query Neighborhood Hits	146	Target Neighborhood Hits	581	Shared Neighborhood Hits	20
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

NGN3_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.102113 (rank : 66)
Query Neighborhood Hits	146	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

PTF1A_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.151786 (rank : 47)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

PTF1A_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.147847 (rank : 50)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

MITF_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.220245 (rank : 31)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	49
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

SCX_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.123923 (rank : 60)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

TFEB_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.192003 (rank : 40)
Query Neighborhood Hits	146	Target Neighborhood Hits	111	Shared Neighborhood Hits	47
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.813845 (rank : 58)	NC score	0.192864 (rank : 39)
Query Neighborhood Hits	146	Target Neighborhood Hits	119	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TWST1_HUMAN
θ value	0.813845 (rank : 59)	NC score	0.144255 (rank : 55)
Query Neighborhood Hits	146	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
θ value	0.813845 (rank : 60)	NC score	0.144372 (rank : 54)
Query Neighborhood Hits	146	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

CEBPE_HUMAN
θ value	1.06291 (rank : 61)	NC score	0.038653 (rank : 124)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

IASPP_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.021131 (rank : 140)
Query Neighborhood Hits	146	Target Neighborhood Hits	688	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IWS1_MOUSE
θ value	1.06291 (rank : 63)	NC score	0.039940 (rank : 121)
Query Neighborhood Hits	146	Target Neighborhood Hits	1258	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AFF1_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.022359 (rank : 138)
Query Neighborhood Hits	146	Target Neighborhood Hits	506	Shared Neighborhood Hits	14
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BMAL1_HUMAN
θ value	1.38821 (rank : 65)	NC score	0.125470 (rank : 58)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	42
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	1.38821 (rank : 66)	NC score	0.125128 (rank : 59)
Query Neighborhood Hits	146	Target Neighborhood Hits	121	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

CNOT3_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.025442 (rank : 132)
Query Neighborhood Hits	146	Target Neighborhood Hits	425	Shared Neighborhood Hits	14
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

HAND2_HUMAN
θ value	1.38821 (rank : 68)	NC score	0.150478 (rank : 48)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.150478 (rank : 49)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

MITF_MOUSE
θ value	1.38821 (rank : 70)	NC score	0.218608 (rank : 32)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	51
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

NGN2_HUMAN
θ value	1.38821 (rank : 71)	NC score	0.095700 (rank : 69)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN2_MOUSE
θ value	1.38821 (rank : 72)	NC score	0.096467 (rank : 68)
Query Neighborhood Hits	146	Target Neighborhood Hits	106	Shared Neighborhood Hits	31
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

PCGF6_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.020187 (rank : 142)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TCOF_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.026749 (rank : 131)
Query Neighborhood Hits	146	Target Neighborhood Hits	543	Shared Neighborhood Hits	19
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ASCL1_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.158647 (rank : 45)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

JPH2_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.019687 (rank : 144)
Query Neighborhood Hits	146	Target Neighborhood Hits	639	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MYO15_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.011347 (rank : 167)
Query Neighborhood Hits	146	Target Neighborhood Hits	671	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PTN23_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.013115 (rank : 158)
Query Neighborhood Hits	146	Target Neighborhood Hits	646	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CJ078_MOUSE
θ value	2.36792 (rank : 79)	NC score	0.025153 (rank : 134)
Query Neighborhood Hits	146	Target Neighborhood Hits	559	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

FOG1_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.006498 (rank : 178)
Query Neighborhood Hits	146	Target Neighborhood Hits	981	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

KI13B_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.010459 (rank : 168)
Query Neighborhood Hits	146	Target Neighborhood Hits	492	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

PRP1_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.018940 (rank : 147)
Query Neighborhood Hits	146	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RERE_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.021287 (rank : 139)
Query Neighborhood Hits	146	Target Neighborhood Hits	779	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RFIP3_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.012219 (rank : 162)
Query Neighborhood Hits	146	Target Neighborhood Hits	1055	Shared Neighborhood Hits	21
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

SOX9_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.011470 (rank : 165)
Query Neighborhood Hits	146	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

ASCL2_MOUSE
θ value	3.0926 (rank : 86)	NC score	0.152494 (rank : 46)
Query Neighborhood Hits	146	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

DOCK6_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.014845 (rank : 157)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

HXA4_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.003043 (rank : 183)
Query Neighborhood Hits	146	Target Neighborhood Hits	370	Shared Neighborhood Hits	7
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

ASCL1_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.147172 (rank : 53)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

ASCL2_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.119045 (rank : 62)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	35
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

BHLH2_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.090150 (rank : 71)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	42
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.089106 (rank : 72)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

CBX2_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.030214 (rank : 126)
Query Neighborhood Hits	146	Target Neighborhood Hits	264	Shared Neighborhood Hits	16
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CEBPE_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.029841 (rank : 127)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PZD9	Gene names	Cebpe
Domain Architecture	No domain graphic available
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CLOCK_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.086422 (rank : 74)
Query Neighborhood Hits	146	Target Neighborhood Hits	127	Shared Neighborhood Hits	29
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.087227 (rank : 73)
Query Neighborhood Hits	146	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CSKI2_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.009160 (rank : 171)
Query Neighborhood Hits	146	Target Neighborhood Hits	747	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.010418 (rank : 169)
Query Neighborhood Hits	146	Target Neighborhood Hits	812	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

EDD1_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.018238 (rank : 153)
Query Neighborhood Hits	146	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.018413 (rank : 151)
Query Neighborhood Hits	146	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

IASPP_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.022515 (rank : 137)
Query Neighborhood Hits	146	Target Neighborhood Hits	1024	Shared Neighborhood Hits	35
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IER5_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.023764 (rank : 136)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

LIMA1_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.016724 (rank : 154)
Query Neighborhood Hits	146	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

PHF20_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.018343 (rank : 152)
Query Neighborhood Hits	146	Target Neighborhood Hits	513	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PO121_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.018868 (rank : 148)
Query Neighborhood Hits	146	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RXRB_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.004073 (rank : 181)
Query Neighborhood Hits	146	Target Neighborhood Hits	280	Shared Neighborhood Hits	11
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

SF01_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.016250 (rank : 156)
Query Neighborhood Hits	146	Target Neighborhood Hits	287	Shared Neighborhood Hits	12
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

ARI1A_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.018793 (rank : 149)
Query Neighborhood Hits	146	Target Neighborhood Hits	787	Shared Neighborhood Hits	36
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CBX2_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.019807 (rank : 143)
Query Neighborhood Hits	146	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

PPWD1_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.007165 (rank : 177)
Query Neighborhood Hits	146	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

SMCA4_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.007566 (rank : 174)
Query Neighborhood Hits	146	Target Neighborhood Hits	597	Shared Neighborhood Hits	20
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMRCD_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.007691 (rank : 173)
Query Neighborhood Hits	146	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

TISD_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.012610 (rank : 159)
Query Neighborhood Hits	146	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

YLPM1_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.020721 (rank : 141)
Query Neighborhood Hits	146	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ATX2L_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.028310 (rank : 128)
Query Neighborhood Hits	146	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CO9A2_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.004006 (rank : 182)
Query Neighborhood Hits	146	Target Neighborhood Hits	261	Shared Neighborhood Hits	12
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

FOG1_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.007178 (rank : 175)
Query Neighborhood Hits	146	Target Neighborhood Hits	1237	Shared Neighborhood Hits	29
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

IWS1_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.027134 (rank : 129)
Query Neighborhood Hits	146	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NFM_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.002086 (rank : 184)
Query Neighborhood Hits	146	Target Neighborhood Hits	1159	Shared Neighborhood Hits	17
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NIBL_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.011730 (rank : 164)
Query Neighborhood Hits	146	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

NPAS2_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.078269 (rank : 82)
Query Neighborhood Hits	146	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.077527 (rank : 84)
Query Neighborhood Hits	146	Target Neighborhood Hits	132	Shared Neighborhood Hits	28
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

RTN4_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.012220 (rank : 161)
Query Neighborhood Hits	146	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TMPSD_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.000421 (rank : 185)
Query Neighborhood Hits	146	Target Neighborhood Hits	333	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

CBL_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.019507 (rank : 145)
Query Neighborhood Hits	146	Target Neighborhood Hits	426	Shared Neighborhood Hits	17
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CIC_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.024059 (rank : 135)
Query Neighborhood Hits	146	Target Neighborhood Hits	992	Shared Neighborhood Hits	49
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.016641 (rank : 155)
Query Neighborhood Hits	146	Target Neighborhood Hits	742	Shared Neighborhood Hits	36
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FBXL6_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.008995 (rank : 172)
Query Neighborhood Hits	146	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

GRIN1_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.026981 (rank : 130)
Query Neighborhood Hits	146	Target Neighborhood Hits	681	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HAND1_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.123385 (rank : 61)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

HAND1_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.129398 (rank : 57)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

IF35_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.011731 (rank : 163)
Query Neighborhood Hits	146	Target Neighborhood Hits	210	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IF4G3_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.007173 (rank : 176)
Query Neighborhood Hits	146	Target Neighborhood Hits	279	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IKBB_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.004412 (rank : 180)
Query Neighborhood Hits	146	Target Neighborhood Hits	284	Shared Neighborhood Hits	6
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

K0323_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.011373 (rank : 166)
Query Neighborhood Hits	146	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U38, Q8BGJ6, Q8C082	Gene names	Kiaa0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

LAMB1_HUMAN
θ value	8.99809 (rank : 136)	NC score	-0.000908 (rank : 187)
Query Neighborhood Hits	146	Target Neighborhood Hits	1018	Shared Neighborhood Hits	4
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MYF6_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.079802 (rank : 80)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.077019 (rank : 85)
Query Neighborhood Hits	146	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

NOLC1_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.018700 (rank : 150)
Query Neighborhood Hits	146	Target Neighborhood Hits	452	Shared Neighborhood Hits	19
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PHLPP_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.005893 (rank : 179)
Query Neighborhood Hits	146	Target Neighborhood Hits	604	Shared Neighborhood Hits	20
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PTN23_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.012274 (rank : 160)
Query Neighborhood Hits	146	Target Neighborhood Hits	726	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RERE_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.019220 (rank : 146)
Query Neighborhood Hits	146	Target Neighborhood Hits	785	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SPEG_HUMAN
θ value	8.99809 (rank : 143)	NC score	-0.002087 (rank : 188)
Query Neighborhood Hits	146	Target Neighborhood Hits	1762	Shared Neighborhood Hits	31
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TFAP4_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.210936 (rank : 34)
Query Neighborhood Hits	146	Target Neighborhood Hits	289	Shared Neighborhood Hits	53
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

TMAP1_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.040291 (rank : 120)
Query Neighborhood Hits	146	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZH7, Q8C6F8	Gene names	Tmap1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

WNK2_HUMAN
θ value	8.99809 (rank : 146)	NC score	-0.000018 (rank : 186)
Query Neighborhood Hits	146	Target Neighborhood Hits	1407	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ASCL3_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.090687 (rank : 70)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

ASCL3_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.085975 (rank : 76)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

ATOH1_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.086359 (rank : 75)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	34
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.085533 (rank : 77)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	33
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

HEN1_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.072363 (rank : 87)
Query Neighborhood Hits	146	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN1_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.072880 (rank : 86)
Query Neighborhood Hits	146	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.070152 (rank : 91)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.069830 (rank : 92)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEY1_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.056511 (rank : 113)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.057086 (rank : 112)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.061432 (rank : 105)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.062685 (rank : 102)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

ID1_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.055240 (rank : 115)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	28
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID1_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.052470 (rank : 116)
Query Neighborhood Hits	146	Target Neighborhood Hits	64	Shared Neighborhood Hits	28
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

LYL1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.067071 (rank : 95)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

LYL1_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.065727 (rank : 98)
Query Neighborhood Hits	146	Target Neighborhood Hits	102	Shared Neighborhood Hits	29
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

MAD1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.140554 (rank : 56)
Query Neighborhood Hits	146	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.191113 (rank : 41)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MUSC_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.061853 (rank : 103)
Query Neighborhood Hits	146	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

MUSC_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.062840 (rank : 101)
Query Neighborhood Hits	146	Target Neighborhood Hits	78	Shared Neighborhood Hits	24
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MYF5_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.060034 (rank : 107)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF5_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.061448 (rank : 104)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYOD1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.059932 (rank : 109)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MYOD1_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.059244 (rank : 110)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MYOG_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.071095 (rank : 88)
Query Neighborhood Hits	146	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.070952 (rank : 89)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

NDF1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.055241 (rank : 114)
Query Neighborhood Hits	146	Target Neighborhood Hits	186	Shared Neighborhood Hits	34
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF1_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.058629 (rank : 111)
Query Neighborhood Hits	146	Target Neighborhood Hits	209	Shared Neighborhood Hits	36
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.079996 (rank : 79)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.079702 (rank : 81)
Query Neighborhood Hits	146	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NGN1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.066838 (rank : 96)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	29
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

NGN1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.067302 (rank : 94)
Query Neighborhood Hits	146	Target Neighborhood Hits	87	Shared Neighborhood Hits	30
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

TAL1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.069699 (rank : 93)
Query Neighborhood Hits	146	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

TAL1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.070241 (rank : 90)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL2_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.066835 (rank : 97)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

TAL2_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.065102 (rank : 100)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

TCF15_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.077845 (rank : 83)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	30
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

TCF15_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.080190 (rank : 78)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

TCF21_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.060461 (rank : 106)
Query Neighborhood Hits	146	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.060008 (rank : 108)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCFL5_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.065700 (rank : 99)
Query Neighborhood Hits	146	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

WBS14_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.099296 (rank : 67)
Query Neighborhood Hits	146	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

Hits sorted by NC score

MYCL1_HUMAN
NC score	0.999962 (rank : 1)	θ value	7.23842e-175 (rank : 1)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	146
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
NC score	0.977155 (rank : 2)	θ value	4.12933e-154 (rank : 2)
Query Neighborhood Hits	146	Target Neighborhood Hits	123	Shared Neighborhood Hits	82
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
NC score	0.944511 (rank : 3)	θ value	1.13238e-127 (rank : 3)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYC_HUMAN
NC score	0.784758 (rank : 4)	θ value	1.16434e-31 (rank : 4)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_MOUSE
NC score	0.784725 (rank : 5)	θ value	3.17079e-29 (rank : 5)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCN_MOUSE
NC score	0.783242 (rank : 6)	θ value	2.27234e-27 (rank : 6)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.778661 (rank : 7)	θ value	1.24688e-25 (rank : 7)
Query Neighborhood Hits	146	Target Neighborhood Hits	127	Shared Neighborhood Hits	58
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
NC score	0.748298 (rank : 8)	θ value	3.51386e-20 (rank : 8)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYCB_MOUSE
NC score	0.607657 (rank : 9)	θ value	1.29631e-06 (rank : 9)
Query Neighborhood Hits	146	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MAX_HUMAN
NC score	0.554125 (rank : 10)	θ value	4.92598e-06 (rank : 10)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
NC score	0.550295 (rank : 11)	θ value	4.92598e-06 (rank : 11)
Query Neighborhood Hits	146	Target Neighborhood Hits	139	Shared Neighborhood Hits	56
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MXI1_MOUSE
NC score	0.328885 (rank : 12)	θ value	0.000461057 (rank : 13)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
NC score	0.317028 (rank : 13)	θ value	0.00175202 (rank : 15)
Query Neighborhood Hits	146	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

USF1_MOUSE
NC score	0.300716 (rank : 14)	θ value	0.0252991 (rank : 24)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	47
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.298176 (rank : 15)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.297245 (rank : 16)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	146	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

MAD3_HUMAN
NC score	0.295018 (rank : 17)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

USF2_MOUSE
NC score	0.294830 (rank : 18)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	55
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MAD4_HUMAN
NC score	0.291756 (rank : 19)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	39
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MNT_MOUSE
NC score	0.279296 (rank : 20)	θ value	0.00298849 (rank : 17)
Query Neighborhood Hits	146	Target Neighborhood Hits	432	Shared Neighborhood Hits	58
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MAD3_MOUSE
NC score	0.277945 (rank : 21)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MNT_HUMAN
NC score	0.271514 (rank : 22)	θ value	0.00298849 (rank : 16)
Query Neighborhood Hits	146	Target Neighborhood Hits	496	Shared Neighborhood Hits	59
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

TFE3_HUMAN
NC score	0.245003 (rank : 23)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	146	Target Neighborhood Hits	190	Shared Neighborhood Hits	49
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MAD4_MOUSE
NC score	0.244848 (rank : 24)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	146	Target Neighborhood Hits	65	Shared Neighborhood Hits	25
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

FIGLA_HUMAN
NC score	0.242827 (rank : 25)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

FIGLA_MOUSE
NC score	0.235450 (rank : 26)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MLX_MOUSE
NC score	0.232636 (rank : 27)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	40
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.230778 (rank : 28)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

SRBP2_HUMAN
NC score	0.228897 (rank : 29)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	146	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

SRBP1_HUMAN
NC score	0.227652 (rank : 30)	θ value	0.00390308 (rank : 20)
Query Neighborhood Hits	146	Target Neighborhood Hits	225	Shared Neighborhood Hits	51
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MITF_HUMAN
NC score	0.220245 (rank : 31)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	49
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.218608 (rank : 32)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	51
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

SRBP1_MOUSE
NC score	0.213318 (rank : 33)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	146	Target Neighborhood Hits	384	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TFAP4_HUMAN
NC score	0.210936 (rank : 34)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	146	Target Neighborhood Hits	289	Shared Neighborhood Hits	53
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

BHLH8_MOUSE
NC score	0.200440 (rank : 35)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

ARNT_HUMAN
NC score	0.197420 (rank : 36)	θ value	0.000786445 (rank : 14)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	42
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
NC score	0.193988 (rank : 37)	θ value	0.000270298 (rank : 12)
Query Neighborhood Hits	146	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BHLH8_HUMAN
NC score	0.193609 (rank : 38)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	146	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

TFEB_MOUSE
NC score	0.192864 (rank : 39)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	146	Target Neighborhood Hits	119	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.192003 (rank : 40)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	146	Target Neighborhood Hits	111	Shared Neighborhood Hits	47
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

MAD1_MOUSE
NC score	0.191113 (rank : 41)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

ARNT2_MOUSE
NC score	0.182085 (rank : 42)	θ value	0.00390308 (rank : 19)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.181403 (rank : 43)	θ value	0.00390308 (rank : 18)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

WBS14_HUMAN
NC score	0.160669 (rank : 44)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	146	Target Neighborhood Hits	273	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

ASCL1_HUMAN
NC score	0.158647 (rank : 45)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

ASCL2_MOUSE
NC score	0.152494 (rank : 46)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	146	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

PTF1A_HUMAN
NC score	0.151786 (rank : 47)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

HAND2_HUMAN
NC score	0.150478 (rank : 48)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
NC score	0.150478 (rank : 49)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

PTF1A_MOUSE
NC score	0.147847 (rank : 50)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

TWST2_MOUSE
NC score	0.147329 (rank : 51)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_HUMAN
NC score	0.147307 (rank : 52)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

ASCL1_MOUSE
NC score	0.147172 (rank : 53)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

TWST1_MOUSE
NC score	0.144372 (rank : 54)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	146	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

TWST1_HUMAN
NC score	0.144255 (rank : 55)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	146	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

MAD1_HUMAN
NC score	0.140554 (rank : 56)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	146	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

HAND1_MOUSE
NC score	0.129398 (rank : 57)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

BMAL1_HUMAN
NC score	0.125470 (rank : 58)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	42
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.125128 (rank : 59)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	146	Target Neighborhood Hits	121	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

SCX_MOUSE
NC score	0.123923 (rank : 60)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

HAND1_HUMAN
NC score	0.123385 (rank : 61)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

ASCL2_HUMAN
NC score	0.119045 (rank : 62)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	35
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

NGN3_HUMAN
NC score	0.118015 (rank : 63)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

BHLH3_HUMAN
NC score	0.111033 (rank : 64)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	146	Target Neighborhood Hits	106	Shared Neighborhood Hits	39
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
NC score	0.107032 (rank : 65)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

NGN3_MOUSE
NC score	0.102113 (rank : 66)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	146	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

WBS14_MOUSE
NC score	0.099296 (rank : 67)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	146	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

NGN2_MOUSE
NC score	0.096467 (rank : 68)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	146	Target Neighborhood Hits	106	Shared Neighborhood Hits	31
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NGN2_HUMAN
NC score	0.095700 (rank : 69)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

ASCL3_HUMAN
NC score	0.090687 (rank : 70)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

BHLH2_HUMAN
NC score	0.090150 (rank : 71)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	42
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
NC score	0.089106 (rank : 72)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

CLOCK_MOUSE
NC score	0.087227 (rank : 73)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	146	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
NC score	0.086422 (rank : 74)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	146	Target Neighborhood Hits	127	Shared Neighborhood Hits	29
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

ATOH1_HUMAN
NC score	0.086359 (rank : 75)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	34
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ASCL3_MOUSE
NC score	0.085975 (rank : 76)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

ATOH1_MOUSE
NC score	0.085533 (rank : 77)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	33
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

TCF15_MOUSE
NC score	0.080190 (rank : 78)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

NDF2_HUMAN
NC score	0.079996 (rank : 79)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

MYF6_HUMAN
NC score	0.079802 (rank : 80)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

NDF2_MOUSE
NC score	0.079702 (rank : 81)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	146	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NPAS2_HUMAN
NC score	0.078269 (rank : 82)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	146	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

TCF15_HUMAN
NC score	0.077845 (rank : 83)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	30
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

NPAS2_MOUSE
NC score	0.077527 (rank : 84)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	146	Target Neighborhood Hits	132	Shared Neighborhood Hits	28
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

MYF6_MOUSE
NC score	0.077019 (rank : 85)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	146	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

HEN1_MOUSE
NC score	0.072880 (rank : 86)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	146	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN1_HUMAN
NC score	0.072363 (rank : 87)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	146	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

MYOG_HUMAN
NC score	0.071095 (rank : 88)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	146	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
NC score	0.070952 (rank : 89)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

TAL1_MOUSE
NC score	0.070241 (rank : 90)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

HEN2_HUMAN
NC score	0.070152 (rank : 91)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
NC score	0.069830 (rank : 92)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

TAL1_HUMAN
NC score	0.069699 (rank : 93)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	146	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

NGN1_MOUSE
NC score	0.067302 (rank : 94)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	146	Target Neighborhood Hits	87	Shared Neighborhood Hits	30
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

LYL1_HUMAN
NC score	0.067071 (rank : 95)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

NGN1_HUMAN
NC score	0.066838 (rank : 96)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	29
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

TAL2_HUMAN
NC score	0.066835 (rank : 97)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

LYL1_MOUSE
NC score	0.065727 (rank : 98)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	146	Target Neighborhood Hits	102	Shared Neighborhood Hits	29
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

TCFL5_HUMAN
NC score	0.065700 (rank : 99)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	146	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TAL2_MOUSE
NC score	0.065102 (rank : 100)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

MUSC_MOUSE
NC score	0.062840 (rank : 101)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	146	Target Neighborhood Hits	78	Shared Neighborhood Hits	24
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

HEY2_MOUSE
NC score	0.062685 (rank : 102)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MUSC_HUMAN
NC score	0.061853 (rank : 103)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	146	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

MYF5_MOUSE
NC score	0.061448 (rank : 104)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

HEY2_HUMAN
NC score	0.061432 (rank : 105)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

TCF21_HUMAN
NC score	0.060461 (rank : 106)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	146	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

MYF5_HUMAN
NC score	0.060034 (rank : 107)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

TCF21_MOUSE
NC score	0.060008 (rank : 108)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

MYOD1_HUMAN
NC score	0.059932 (rank : 109)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MYOD1_MOUSE
NC score	0.059244 (rank : 110)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

NDF1_MOUSE
NC score	0.058629 (rank : 111)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	146	Target Neighborhood Hits	209	Shared Neighborhood Hits	36
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

HEY1_MOUSE
NC score	0.057086 (rank : 112)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY1_HUMAN
NC score	0.056511 (rank : 113)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

NDF1_HUMAN
NC score	0.055241 (rank : 114)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	146	Target Neighborhood Hits	186	Shared Neighborhood Hits	34
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

ID1_HUMAN
NC score	0.055240 (rank : 115)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	28
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID1_MOUSE
NC score	0.052470 (rank : 116)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	146	Target Neighborhood Hits	64	Shared Neighborhood Hits	28
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

KI67_HUMAN
NC score	0.044622 (rank : 117)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	146	Target Neighborhood Hits	581	Shared Neighborhood Hits	20
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

NF2L1_MOUSE
NC score	0.043857 (rank : 118)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	146	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

TBCD2_HUMAN
NC score	0.040966 (rank : 119)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	146	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

TMAP1_MOUSE
NC score	0.040291 (rank : 120)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	146	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZH7, Q8C6F8	Gene names	Tmap1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

IWS1_MOUSE
NC score	0.039940 (rank : 121)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	146	Target Neighborhood Hits	1258	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BAT3_MOUSE
NC score	0.039012 (rank : 122)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	146	Target Neighborhood Hits	518	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

REXO1_HUMAN
NC score	0.039003 (rank : 123)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	146	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

CEBPE_HUMAN
NC score	0.038653 (rank : 124)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

MINT_HUMAN
NC score	0.034168 (rank : 125)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	146	Target Neighborhood Hits	1291	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CBX2_HUMAN
NC score	0.030214 (rank : 126)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	146	Target Neighborhood Hits	264	Shared Neighborhood Hits	16
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CEBPE_MOUSE
NC score	0.029841 (rank : 127)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PZD9	Gene names	Cebpe
Domain Architecture	No domain graphic available
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

ATX2L_MOUSE
NC score	0.028310 (rank : 128)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	146	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

IWS1_HUMAN
NC score	0.027134 (rank : 129)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	146	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

GRIN1_HUMAN
NC score	0.026981 (rank : 130)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	146	Target Neighborhood Hits	681	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

TCOF_HUMAN
NC score	0.026749 (rank : 131)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	146	Target Neighborhood Hits	543	Shared Neighborhood Hits	19
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CNOT3_HUMAN
NC score	0.025442 (rank : 132)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	146	Target Neighborhood Hits	425	Shared Neighborhood Hits	14
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

APS_HUMAN
NC score	0.025411 (rank : 133)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	146	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

CJ078_MOUSE
NC score	0.025153 (rank : 134)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	146	Target Neighborhood Hits	559	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CIC_HUMAN
NC score	0.024059 (rank : 135)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	146	Target Neighborhood Hits	992	Shared Neighborhood Hits	49
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

IER5_MOUSE
NC score	0.023764 (rank : 136)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IASPP_MOUSE
NC score	0.022515 (rank : 137)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	146	Target Neighborhood Hits	1024	Shared Neighborhood Hits	35
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

AFF1_HUMAN
NC score	0.022359 (rank : 138)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	146	Target Neighborhood Hits	506	Shared Neighborhood Hits	14
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

RERE_HUMAN
NC score	0.021287 (rank : 139)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	146	Target Neighborhood Hits	779	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

IASPP_HUMAN
NC score	0.021131 (rank : 140)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	146	Target Neighborhood Hits	688	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

YLPM1_HUMAN
NC score	0.020721 (rank : 141)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	146	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

PCGF6_HUMAN
NC score	0.020187 (rank : 142)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

CBX2_MOUSE
NC score	0.019807 (rank : 143)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	146	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

JPH2_HUMAN
NC score	0.019687 (rank : 144)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	146	Target Neighborhood Hits	639	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CBL_MOUSE
NC score	0.019507 (rank : 145)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	146	Target Neighborhood Hits	426	Shared Neighborhood Hits	17
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

RERE_MOUSE
NC score	0.019220 (rank : 146)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	146	Target Neighborhood Hits	785	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

PRP1_HUMAN
NC score	0.018940 (rank : 147)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	146	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PO121_HUMAN
NC score	0.018868 (rank : 148)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	146	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

ARI1A_HUMAN
NC score	0.018793 (rank : 149)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	146	Target Neighborhood Hits	787	Shared Neighborhood Hits	36
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

NOLC1_HUMAN
NC score	0.018700 (rank : 150)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	146	Target Neighborhood Hits	452	Shared Neighborhood Hits	19
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

EDD1_MOUSE
NC score	0.018413 (rank : 151)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	146	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

PHF20_MOUSE
NC score	0.018343 (rank : 152)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	146	Target Neighborhood Hits	513	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

EDD1_HUMAN
NC score	0.018238 (rank : 153)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	146	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

LIMA1_MOUSE
NC score	0.016724 (rank : 154)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	146	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

CIC_MOUSE
NC score	0.016641 (rank : 155)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	146	Target Neighborhood Hits	742	Shared Neighborhood Hits	36
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SF01_HUMAN
NC score	0.016250 (rank : 156)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	146	Target Neighborhood Hits	287	Shared Neighborhood Hits	12
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

DOCK6_HUMAN
NC score	0.014845 (rank : 157)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

PTN23_HUMAN
NC score	0.013115 (rank : 158)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	146	Target Neighborhood Hits	646	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

TISD_MOUSE
NC score	0.012610 (rank : 159)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	146	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

PTN23_MOUSE
NC score	0.012274 (rank : 160)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	146	Target Neighborhood Hits	726	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RTN4_HUMAN
NC score	0.012220 (rank : 161)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	146	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RFIP3_HUMAN
NC score	0.012219 (rank : 162)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	146	Target Neighborhood Hits	1055	Shared Neighborhood Hits	21
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

IF35_MOUSE
NC score	0.011731 (rank : 163)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	146	Target Neighborhood Hits	210	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

NIBL_HUMAN
NC score	0.011730 (rank : 164)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	146	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

SOX9_HUMAN
NC score	0.011470 (rank : 165)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	146	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

K0323_MOUSE
NC score	0.011373 (rank : 166)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	146	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U38, Q8BGJ6, Q8C082	Gene names	Kiaa0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

MYO15_HUMAN
NC score	0.011347 (rank : 167)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	146	Target Neighborhood Hits	671	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

KI13B_HUMAN
NC score	0.010459 (rank : 168)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	146	Target Neighborhood Hits	492	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

CSKI2_MOUSE
NC score	0.010418 (rank : 169)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	146	Target Neighborhood Hits	812	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

SALL3_HUMAN
NC score	0.010405 (rank : 170)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	146	Target Neighborhood Hits	1066	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

CSKI2_HUMAN
NC score	0.009160 (rank : 171)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	146	Target Neighborhood Hits	747	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FBXL6_HUMAN
NC score	0.008995 (rank : 172)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	146	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N531, Q9H5W9, Q9UKC7	Gene names	FBXL6, FBL6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6) (FBL6A).

SMRCD_MOUSE
NC score	0.007691 (rank : 173)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	146	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMCA4_HUMAN
NC score	0.007566 (rank : 174)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	146	Target Neighborhood Hits	597	Shared Neighborhood Hits	20
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

FOG1_MOUSE
NC score	0.007178 (rank : 175)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	146	Target Neighborhood Hits	1237	Shared Neighborhood Hits	29
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

IF4G3_MOUSE
NC score	0.007173 (rank : 176)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	146	Target Neighborhood Hits	279	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

PPWD1_MOUSE
NC score	0.007165 (rank : 177)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	146	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

FOG1_HUMAN
NC score	0.006498 (rank : 178)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	146	Target Neighborhood Hits	981	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PHLPP_HUMAN
NC score	0.005893 (rank : 179)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	146	Target Neighborhood Hits	604	Shared Neighborhood Hits	20
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

IKBB_HUMAN
NC score	0.004412 (rank : 180)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	146	Target Neighborhood Hits	284	Shared Neighborhood Hits	6
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

RXRB_HUMAN
NC score	0.004073 (rank : 181)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	146	Target Neighborhood Hits	280	Shared Neighborhood Hits	11
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

CO9A2_HUMAN
NC score	0.004006 (rank : 182)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	146	Target Neighborhood Hits	261	Shared Neighborhood Hits	12
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

HXA4_HUMAN
NC score	0.003043 (rank : 183)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	146	Target Neighborhood Hits	370	Shared Neighborhood Hits	7
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

NFM_MOUSE
NC score	0.002086 (rank : 184)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	146	Target Neighborhood Hits	1159	Shared Neighborhood Hits	17
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

TMPSD_HUMAN
NC score	0.000421 (rank : 185)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	146	Target Neighborhood Hits	333	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

WNK2_HUMAN
NC score	-0.000018 (rank : 186)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	146	Target Neighborhood Hits	1407	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

LAMB1_HUMAN
NC score	-0.000908 (rank : 187)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	146	Target Neighborhood Hits	1018	Shared Neighborhood Hits	4
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SPEG_HUMAN
NC score	-0.002087 (rank : 188)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	146	Target Neighborhood Hits	1762	Shared Neighborhood Hits	31
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).