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Network neighborhood for query Sequence : MYC_MOUSE

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MYC_MOUSE
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MYC_MOUSE
θ value	7.71569e-185 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
θ value	1.19313e-177 (rank : 2)	NC score	0.977625 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	93
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCB_MOUSE
θ value	1.85029e-45 (rank : 3)	NC score	0.830056 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MYCS_MOUSE
θ value	4.72714e-33 (rank : 4)	NC score	0.809443 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYCN_HUMAN
θ value	8.06329e-33 (rank : 5)	NC score	0.827060 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_MOUSE
θ value	3.06405e-32 (rank : 6)	NC score	0.827098 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCL1_HUMAN
θ value	3.17079e-29 (rank : 7)	NC score	0.784725 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	62
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
θ value	7.0802e-21 (rank : 8)	NC score	0.750381 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
θ value	1.47631e-18 (rank : 9)	NC score	0.712192 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MAX_HUMAN
θ value	1.25267e-09 (rank : 10)	NC score	0.622796 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
θ value	1.38499e-08 (rank : 11)	NC score	0.612754 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	139	Shared Neighborhood Hits	63
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MAD3_HUMAN
θ value	5.81887e-07 (rank : 12)	NC score	0.386049 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	1.29631e-06 (rank : 13)	NC score	0.379278 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	30
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MXI1_MOUSE
θ value	1.69304e-06 (rank : 14)	NC score	0.394275 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
θ value	2.88788e-06 (rank : 15)	NC score	0.387163 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	33
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

USF1_MOUSE
θ value	1.09739e-05 (rank : 16)	NC score	0.372626 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MNT_HUMAN
θ value	3.19293e-05 (rank : 17)	NC score	0.350142 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	496	Shared Neighborhood Hits	58
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	3.19293e-05 (rank : 18)	NC score	0.359358 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	432	Shared Neighborhood Hits	58
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

USF1_HUMAN
θ value	3.19293e-05 (rank : 19)	NC score	0.367768 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

SRBP2_HUMAN
θ value	0.00020696 (rank : 20)	NC score	0.282593 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	133	Shared Neighborhood Hits	41
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

MAD4_HUMAN
θ value	0.00035302 (rank : 21)	NC score	0.359403 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	35
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

PTF1A_HUMAN
θ value	0.000602161 (rank : 22)	NC score	0.242060 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

BHLH8_MOUSE
θ value	0.00134147 (rank : 23)	NC score	0.269632 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MAD4_MOUSE
θ value	0.00228821 (rank : 24)	NC score	0.318226 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

FIGLA_MOUSE
θ value	0.00298849 (rank : 25)	NC score	0.324289 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

FIGLA_HUMAN
θ value	0.00390308 (rank : 26)	NC score	0.320960 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	108	Shared Neighborhood Hits	45
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

USF2_HUMAN
θ value	0.00390308 (rank : 27)	NC score	0.364873 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.00390308 (rank : 28)	NC score	0.362055 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	173	Shared Neighborhood Hits	46
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MLX_HUMAN
θ value	0.00509761 (rank : 29)	NC score	0.287996 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	0.00509761 (rank : 30)	NC score	0.289930 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

TFAP4_HUMAN
θ value	0.00665767 (rank : 31)	NC score	0.342529 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	289	Shared Neighborhood Hits	61
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

TWST2_HUMAN
θ value	0.00869519 (rank : 32)	NC score	0.223038 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
θ value	0.00869519 (rank : 33)	NC score	0.223139 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

BHLH8_HUMAN
θ value	0.0113563 (rank : 34)	NC score	0.260937 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	123	Shared Neighborhood Hits	49
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

ATOH1_HUMAN
θ value	0.0148317 (rank : 35)	NC score	0.166036 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
θ value	0.0148317 (rank : 36)	NC score	0.165779 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

SRBP1_MOUSE
θ value	0.0148317 (rank : 37)	NC score	0.241253 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MYOG_HUMAN
θ value	0.0193708 (rank : 38)	NC score	0.209368 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
θ value	0.0193708 (rank : 39)	NC score	0.209239 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

SRBP1_HUMAN
θ value	0.0193708 (rank : 40)	NC score	0.249307 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	42
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

WBS14_HUMAN
θ value	0.0252991 (rank : 41)	NC score	0.185908 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	273	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

MYF6_HUMAN
θ value	0.0330416 (rank : 42)	NC score	0.204970 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
θ value	0.0431538 (rank : 43)	NC score	0.200885 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

ASCL2_MOUSE
θ value	0.0563607 (rank : 44)	NC score	0.231165 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

PTF1A_MOUSE
θ value	0.0563607 (rank : 45)	NC score	0.229715 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

SCX_MOUSE
θ value	0.0563607 (rank : 46)	NC score	0.187368 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

WBS14_MOUSE
θ value	0.0563607 (rank : 47)	NC score	0.153636 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	171	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ARNT_HUMAN
θ value	0.0736092 (rank : 48)	NC score	0.137753 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

TWST1_HUMAN
θ value	0.0736092 (rank : 49)	NC score	0.222770 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
θ value	0.0736092 (rank : 50)	NC score	0.222334 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

IWS1_MOUSE
θ value	0.0961366 (rank : 51)	NC score	0.044461 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	1258	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TXND2_MOUSE
θ value	0.0961366 (rank : 52)	NC score	0.031624 (rank : 136)
Query Neighborhood Hits	125	Target Neighborhood Hits	828	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

MITF_MOUSE
θ value	0.125558 (rank : 53)	NC score	0.246798 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFE3_HUMAN
θ value	0.125558 (rank : 54)	NC score	0.266479 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

ARNT_MOUSE
θ value	0.163984 (rank : 55)	NC score	0.131563 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	213	Shared Neighborhood Hits	32
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MITF_HUMAN
θ value	0.163984 (rank : 56)	NC score	0.250261 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	41
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

ARNT2_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.122023 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	0.21417 (rank : 58)	NC score	0.122717 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	30
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

HAND2_HUMAN
θ value	0.21417 (rank : 59)	NC score	0.215401 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
θ value	0.21417 (rank : 60)	NC score	0.215401 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

MYOD1_MOUSE
θ value	0.21417 (rank : 61)	NC score	0.173434 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

CP250_MOUSE
θ value	0.279714 (rank : 62)	NC score	0.015380 (rank : 168)
Query Neighborhood Hits	125	Target Neighborhood Hits	1583	Shared Neighborhood Hits	30
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MYOD1_HUMAN
θ value	0.279714 (rank : 63)	NC score	0.170834 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

PZRN3_HUMAN
θ value	0.279714 (rank : 64)	NC score	0.040742 (rank : 129)
Query Neighborhood Hits	125	Target Neighborhood Hits	461	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

UBP28_MOUSE
θ value	0.279714 (rank : 65)	NC score	0.033233 (rank : 134)
Query Neighborhood Hits	125	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

ASCL1_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.218984 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

ASCL1_MOUSE
θ value	0.365318 (rank : 67)	NC score	0.209748 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	97	Shared Neighborhood Hits	41
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

DHX16_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.022009 (rank : 153)
Query Neighborhood Hits	125	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

FGF23_HUMAN
θ value	0.365318 (rank : 69)	NC score	0.030673 (rank : 138)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZV9, Q4V758	Gene names	FGF23, HYPF
Domain Architecture
Description	Fibroblast growth factor 23 precursor (FGF-23) (Tumor-derived hypophosphatemia-inducing factor).

OXR1_MOUSE
θ value	0.365318 (rank : 70)	NC score	0.030608 (rank : 139)
Query Neighborhood Hits	125	Target Neighborhood Hits	516	Shared Neighborhood Hits	14
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

SNX23_HUMAN
θ value	0.365318 (rank : 71)	NC score	0.015966 (rank : 166)
Query Neighborhood Hits	125	Target Neighborhood Hits	944	Shared Neighborhood Hits	17
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

DTNA_HUMAN
θ value	0.47712 (rank : 72)	NC score	0.032699 (rank : 135)
Query Neighborhood Hits	125	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

MYF5_HUMAN
θ value	0.47712 (rank : 73)	NC score	0.170629 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF5_MOUSE
θ value	0.47712 (rank : 74)	NC score	0.171269 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

ASXL1_HUMAN
θ value	0.62314 (rank : 75)	NC score	0.036309 (rank : 132)
Query Neighborhood Hits	125	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

K0586_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.045939 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	311	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

LPIN1_MOUSE
θ value	0.62314 (rank : 77)	NC score	0.021717 (rank : 155)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZP3, Q9CQI2, Q9JLG6	Gene names	Lpin1, Fld
Domain Architecture
Description	Lipin-1 (Fatty liver dystrophy protein).

TFEB_HUMAN
θ value	0.62314 (rank : 78)	NC score	0.208625 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	37
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.209317 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	119	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

RBBP6_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.025862 (rank : 148)
Query Neighborhood Hits	125	Target Neighborhood Hits	1135	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

PZRN3_MOUSE
θ value	1.06291 (rank : 81)	NC score	0.034966 (rank : 133)
Query Neighborhood Hits	125	Target Neighborhood Hits	447	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ATRX_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.024647 (rank : 150)
Query Neighborhood Hits	125	Target Neighborhood Hits	842	Shared Neighborhood Hits	22
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

DTNA_MOUSE
θ value	1.38821 (rank : 83)	NC score	0.029414 (rank : 142)
Query Neighborhood Hits	125	Target Neighborhood Hits	264	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

KIF3A_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.018803 (rank : 159)
Query Neighborhood Hits	125	Target Neighborhood Hits	704	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

CCD91_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.022267 (rank : 152)
Query Neighborhood Hits	125	Target Neighborhood Hits	868	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

SDC2_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.028242 (rank : 144)
Query Neighborhood Hits	125	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P43407	Gene names	Sdc2, Hspg1, Synd2
Domain Architecture
Description	Syndecan-2 precursor (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG).

TARA_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.025919 (rank : 147)
Query Neighborhood Hits	125	Target Neighborhood Hits	1626	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCF15_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.139190 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

DACT1_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.020748 (rank : 157)
Query Neighborhood Hits	125	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

HAND1_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.179708 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

HAND1_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.191907 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

IWS1_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.029488 (rank : 141)
Query Neighborhood Hits	125	Target Neighborhood Hits	1241	Shared Neighborhood Hits	19
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K0319_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.036520 (rank : 130)
Query Neighborhood Hits	125	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

KLRA2_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.013892 (rank : 170)
Query Neighborhood Hits	125	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q60660	Gene names	Klra2, Ly49-b, Ly49b
Domain Architecture
Description	Killer cell lectin-like receptor 2 (T-cell surface glycoprotein Ly- 49B) (Ly49-B antigen) (Lymphocyte antigen 49B).

SAFB2_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.016467 (rank : 164)
Query Neighborhood Hits	125	Target Neighborhood Hits	720	Shared Neighborhood Hits	17
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

STX18_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.024782 (rank : 149)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

TRHY_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.022462 (rank : 151)
Query Neighborhood Hits	125	Target Neighborhood Hits	1385	Shared Neighborhood Hits	37
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ACINU_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.046497 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	828	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BAZ2A_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.015699 (rank : 167)
Query Neighborhood Hits	125	Target Neighborhood Hits	780	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CEBPE_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.030426 (rank : 140)
Query Neighborhood Hits	125	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

FBX38_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.026571 (rank : 146)
Query Neighborhood Hits	125	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

JHD2C_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.014335 (rank : 169)
Query Neighborhood Hits	125	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

METL2_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.036458 (rank : 131)
Query Neighborhood Hits	125	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

REN3B_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.021557 (rank : 156)
Query Neighborhood Hits	125	Target Neighborhood Hits	412	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

FA21C_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.028903 (rank : 143)
Query Neighborhood Hits	125	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

K0056_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.016648 (rank : 162)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

TCF15_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.128105 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

TTC14_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.027540 (rank : 145)
Query Neighborhood Hits	125	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

ZFYV1_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.018547 (rank : 160)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

NFH_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.018350 (rank : 161)
Query Neighborhood Hits	125	Target Neighborhood Hits	2247	Shared Neighborhood Hits	42
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TARA_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.021731 (rank : 154)
Query Neighborhood Hits	125	Target Neighborhood Hits	1133	Shared Neighborhood Hits	21
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MTR1L_HUMAN
θ value	6.88961 (rank : 112)	NC score	-0.003242 (rank : 180)
Query Neighborhood Hits	125	Target Neighborhood Hits	1180	Shared Neighborhood Hits	8
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

NEMO_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.018948 (rank : 158)
Query Neighborhood Hits	125	Target Neighborhood Hits	820	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NUFP1_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.013107 (rank : 171)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXX8, Q9CV69	Gene names	Nufip1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

PTPRD_HUMAN
θ value	6.88961 (rank : 115)	NC score	-0.000931 (rank : 179)
Query Neighborhood Hits	125	Target Neighborhood Hits	485	Shared Neighborhood Hits	2
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

ASXL1_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.030757 (rank : 137)
Query Neighborhood Hits	125	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CEBPA_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.016488 (rank : 163)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CEBPA_MOUSE
θ value	8.99809 (rank : 118)	NC score	0.016298 (rank : 165)
Query Neighborhood Hits	125	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CROCC_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.009427 (rank : 176)
Query Neighborhood Hits	125	Target Neighborhood Hits	1409	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGA1_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.007526 (rank : 177)
Query Neighborhood Hits	125	Target Neighborhood Hits	994	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GP149_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.009945 (rank : 173)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

INCE_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.009912 (rank : 174)
Query Neighborhood Hits	125	Target Neighborhood Hits	903	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

MAST4_HUMAN
θ value	8.99809 (rank : 123)	NC score	-0.000510 (rank : 178)
Query Neighborhood Hits	125	Target Neighborhood Hits	1804	Shared Neighborhood Hits	24
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MY18A_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.009600 (rank : 175)
Query Neighborhood Hits	125	Target Neighborhood Hits	1989	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NUP88_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.012654 (rank : 172)
Query Neighborhood Hits	125	Target Neighborhood Hits	239	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

ASCL2_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.166572 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

ASCL3_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.153844 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

ASCL3_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.149600 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

BHLH2_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.055899 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.055454 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

BHLH3_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.063686 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.058417 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BHLH4_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.070855 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BHLH4_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.068770 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BMAL1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.078686 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	36
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.078260 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	121	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

HEN1_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.106234 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN1_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.107107 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.103685 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.103030 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEY1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.051717 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.051343 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.054195 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.056069 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

ID1_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.077927 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID1_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.072241 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID4_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.050867 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P47928, Q13005	Gene names	ID4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

LYL1_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.113312 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

LYL1_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.113896 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

MAD1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.205753 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.246176 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MUSC_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.091094 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

MUSC_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.092076 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

NDF1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.084301 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	186	Shared Neighborhood Hits	38
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.085424 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	209	Shared Neighborhood Hits	38
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.106126 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.106338 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	39
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF4_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.075330 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

NDF4_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.076220 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

NDF6_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.064284 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.063847 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

NGN1_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.098452 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

NGN1_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.101286 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

NGN2_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.109412 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN2_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.111566 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NGN3_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.124683 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

NGN3_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.117041 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

OLIG1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.065848 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OLIG1_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.063995 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

OLIG2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.065021 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.063941 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

OLIG3_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.061127 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

OLIG3_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.062446 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

TAL1_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.125370 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

TAL1_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.127236 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL2_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.107591 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

TAL2_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.109667 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

TCF21_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.088338 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.087753 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCFL5_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.070245 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

Hits sorted by NC score

MYC_MOUSE
NC score	0.999962 (rank : 1)	θ value	7.71569e-185 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
NC score	0.977625 (rank : 2)	θ value	1.19313e-177 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	93
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCB_MOUSE
NC score	0.830056 (rank : 3)	θ value	1.85029e-45 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MYCN_MOUSE
NC score	0.827098 (rank : 4)	θ value	3.06405e-32 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.827060 (rank : 5)	θ value	8.06329e-33 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
NC score	0.809443 (rank : 6)	θ value	4.72714e-33 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYCL1_HUMAN
NC score	0.784725 (rank : 7)	θ value	3.17079e-29 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	62
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
NC score	0.750381 (rank : 8)	θ value	7.0802e-21 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
NC score	0.712192 (rank : 9)	θ value	1.47631e-18 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MAX_HUMAN
NC score	0.622796 (rank : 10)	θ value	1.25267e-09 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
NC score	0.612754 (rank : 11)	θ value	1.38499e-08 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	139	Shared Neighborhood Hits	63
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MXI1_MOUSE
NC score	0.394275 (rank : 12)	θ value	1.69304e-06 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
NC score	0.387163 (rank : 13)	θ value	2.88788e-06 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	33
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD3_HUMAN
NC score	0.386049 (rank : 14)	θ value	5.81887e-07 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
NC score	0.379278 (rank : 15)	θ value	1.29631e-06 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	30
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

USF1_MOUSE
NC score	0.372626 (rank : 16)	θ value	1.09739e-05 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.367768 (rank : 17)	θ value	3.19293e-05 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.364873 (rank : 18)	θ value	0.00390308 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
NC score	0.362055 (rank : 19)	θ value	0.00390308 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	173	Shared Neighborhood Hits	46
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MAD4_HUMAN
NC score	0.359403 (rank : 20)	θ value	0.00035302 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	35
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MNT_MOUSE
NC score	0.359358 (rank : 21)	θ value	3.19293e-05 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	432	Shared Neighborhood Hits	58
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
NC score	0.350142 (rank : 22)	θ value	3.19293e-05 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	496	Shared Neighborhood Hits	58
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

TFAP4_HUMAN
NC score	0.342529 (rank : 23)	θ value	0.00665767 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	289	Shared Neighborhood Hits	61
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

FIGLA_MOUSE
NC score	0.324289 (rank : 24)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

FIGLA_HUMAN
NC score	0.320960 (rank : 25)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	108	Shared Neighborhood Hits	45
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MAD4_MOUSE
NC score	0.318226 (rank : 26)	θ value	0.00228821 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MLX_MOUSE
NC score	0.289930 (rank : 27)	θ value	0.00509761 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.287996 (rank : 28)	θ value	0.00509761 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

SRBP2_HUMAN
NC score	0.282593 (rank : 29)	θ value	0.00020696 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	133	Shared Neighborhood Hits	41
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

BHLH8_MOUSE
NC score	0.269632 (rank : 30)	θ value	0.00134147 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

TFE3_HUMAN
NC score	0.266479 (rank : 31)	θ value	0.125558 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

BHLH8_HUMAN
NC score	0.260937 (rank : 32)	θ value	0.0113563 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	123	Shared Neighborhood Hits	49
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MITF_HUMAN
NC score	0.250261 (rank : 33)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	41
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

SRBP1_HUMAN
NC score	0.249307 (rank : 34)	θ value	0.0193708 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	42
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MITF_MOUSE
NC score	0.246798 (rank : 35)	θ value	0.125558 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MAD1_MOUSE
NC score	0.246176 (rank : 36)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	125	Target Neighborhood Hits	75	Shared Neighborhood Hits	32
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

PTF1A_HUMAN
NC score	0.242060 (rank : 37)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

SRBP1_MOUSE
NC score	0.241253 (rank : 38)	θ value	0.0148317 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ASCL2_MOUSE
NC score	0.231165 (rank : 39)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

PTF1A_MOUSE
NC score	0.229715 (rank : 40)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

TWST2_MOUSE
NC score	0.223139 (rank : 41)	θ value	0.00869519 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_HUMAN
NC score	0.223038 (rank : 42)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST1_HUMAN
NC score	0.222770 (rank : 43)	θ value	0.0736092 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
NC score	0.222334 (rank : 44)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

ASCL1_HUMAN
NC score	0.218984 (rank : 45)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

HAND2_HUMAN
NC score	0.215401 (rank : 46)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
NC score	0.215401 (rank : 47)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

ASCL1_MOUSE
NC score	0.209748 (rank : 48)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	97	Shared Neighborhood Hits	41
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

MYOG_HUMAN
NC score	0.209368 (rank : 49)	θ value	0.0193708 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

TFEB_MOUSE
NC score	0.209317 (rank : 50)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	119	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

MYOG_MOUSE
NC score	0.209239 (rank : 51)	θ value	0.0193708 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

TFEB_HUMAN
NC score	0.208625 (rank : 52)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	37
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

MAD1_HUMAN
NC score	0.205753 (rank : 53)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MYF6_HUMAN
NC score	0.204970 (rank : 54)	θ value	0.0330416 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
NC score	0.200885 (rank : 55)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

HAND1_MOUSE
NC score	0.191907 (rank : 56)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

SCX_MOUSE
NC score	0.187368 (rank : 57)	θ value	0.0563607 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

WBS14_HUMAN
NC score	0.185908 (rank : 58)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	273	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

HAND1_HUMAN
NC score	0.179708 (rank : 59)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

MYOD1_MOUSE
NC score	0.173434 (rank : 60)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MYF5_MOUSE
NC score	0.171269 (rank : 61)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYOD1_HUMAN
NC score	0.170834 (rank : 62)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MYF5_HUMAN
NC score	0.170629 (rank : 63)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

ASCL2_HUMAN
NC score	0.166572 (rank : 64)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

ATOH1_HUMAN
NC score	0.166036 (rank : 65)	θ value	0.0148317 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
NC score	0.165779 (rank : 66)	θ value	0.0148317 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

ASCL3_HUMAN
NC score	0.153844 (rank : 67)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

WBS14_MOUSE
NC score	0.153636 (rank : 68)	θ value	0.0563607 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	171	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ASCL3_MOUSE
NC score	0.149600 (rank : 69)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

TCF15_MOUSE
NC score	0.139190 (rank : 70)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

ARNT_HUMAN
NC score	0.137753 (rank : 71)	θ value	0.0736092 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
NC score	0.131563 (rank : 72)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	213	Shared Neighborhood Hits	32
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

TCF15_HUMAN
NC score	0.128105 (rank : 73)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

TAL1_MOUSE
NC score	0.127236 (rank : 74)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	125	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL1_HUMAN
NC score	0.125370 (rank : 75)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	125	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

NGN3_HUMAN
NC score	0.124683 (rank : 76)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

ARNT2_MOUSE
NC score	0.122717 (rank : 77)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	30
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.122023 (rank : 78)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

NGN3_MOUSE
NC score	0.117041 (rank : 79)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	125	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

LYL1_MOUSE
NC score	0.113896 (rank : 80)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	125	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

LYL1_HUMAN
NC score	0.113312 (rank : 81)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

NGN2_MOUSE
NC score	0.111566 (rank : 82)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	125	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

TAL2_MOUSE
NC score	0.109667 (rank : 83)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

NGN2_HUMAN
NC score	0.109412 (rank : 84)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	125	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

TAL2_HUMAN
NC score	0.107591 (rank : 85)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

HEN1_MOUSE
NC score	0.107107 (rank : 86)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	125	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

NDF2_MOUSE
NC score	0.106338 (rank : 87)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	39
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

HEN1_HUMAN
NC score	0.106234 (rank : 88)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	125	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

NDF2_HUMAN
NC score	0.106126 (rank : 89)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

HEN2_HUMAN
NC score	0.103685 (rank : 90)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
NC score	0.103030 (rank : 91)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

NGN1_MOUSE
NC score	0.101286 (rank : 92)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	125	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

NGN1_HUMAN
NC score	0.098452 (rank : 93)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

MUSC_MOUSE
NC score	0.092076 (rank : 94)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MUSC_HUMAN
NC score	0.091094 (rank : 95)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

TCF21_HUMAN
NC score	0.088338 (rank : 96)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
NC score	0.087753 (rank : 97)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

NDF1_MOUSE
NC score	0.085424 (rank : 98)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	125	Target Neighborhood Hits	209	Shared Neighborhood Hits	38
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF1_HUMAN
NC score	0.084301 (rank : 99)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	125	Target Neighborhood Hits	186	Shared Neighborhood Hits	38
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

BMAL1_HUMAN
NC score	0.078686 (rank : 100)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	36
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.078260 (rank : 101)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	125	Target Neighborhood Hits	121	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

ID1_HUMAN
NC score	0.077927 (rank : 102)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	125	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

NDF4_MOUSE
NC score	0.076220 (rank : 103)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	125	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

NDF4_HUMAN
NC score	0.075330 (rank : 104)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	125	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

ID1_MOUSE
NC score	0.072241 (rank : 105)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	125	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

BHLH4_HUMAN
NC score	0.070855 (rank : 106)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

TCFL5_HUMAN
NC score	0.070245 (rank : 107)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	125	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

BHLH4_MOUSE
NC score	0.068770 (rank : 108)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

OLIG1_HUMAN
NC score	0.065848 (rank : 109)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OLIG2_HUMAN
NC score	0.065021 (rank : 110)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	125	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

NDF6_HUMAN
NC score	0.064284 (rank : 111)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	125	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

OLIG1_MOUSE
NC score	0.063995 (rank : 112)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

OLIG2_MOUSE
NC score	0.063941 (rank : 113)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

NDF6_MOUSE
NC score	0.063847 (rank : 114)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

BHLH3_HUMAN
NC score	0.063686 (rank : 115)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	125	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

OLIG3_MOUSE
NC score	0.062446 (rank : 116)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

OLIG3_HUMAN
NC score	0.061127 (rank : 117)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

BHLH3_MOUSE
NC score	0.058417 (rank : 118)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

HEY2_MOUSE
NC score	0.056069 (rank : 119)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

BHLH2_HUMAN
NC score	0.055899 (rank : 120)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
NC score	0.055454 (rank : 121)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

HEY2_HUMAN
NC score	0.054195 (rank : 122)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY1_HUMAN
NC score	0.051717 (rank : 123)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
NC score	0.051343 (rank : 124)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

ID4_HUMAN
NC score	0.050867 (rank : 125)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P47928, Q13005	Gene names	ID4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

ACINU_HUMAN
NC score	0.046497 (rank : 126)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	828	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

K0586_HUMAN
NC score	0.045939 (rank : 127)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	311	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

IWS1_MOUSE
NC score	0.044461 (rank : 128)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	1258	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PZRN3_HUMAN
NC score	0.040742 (rank : 129)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	461	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

K0319_MOUSE
NC score	0.036520 (rank : 130)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

METL2_HUMAN
NC score	0.036458 (rank : 131)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

ASXL1_HUMAN
NC score	0.036309 (rank : 132)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

PZRN3_MOUSE
NC score	0.034966 (rank : 133)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	447	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

UBP28_MOUSE
NC score	0.033233 (rank : 134)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

DTNA_HUMAN
NC score	0.032699 (rank : 135)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

TXND2_MOUSE
NC score	0.031624 (rank : 136)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	828	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ASXL1_MOUSE
NC score	0.030757 (rank : 137)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

FGF23_HUMAN
NC score	0.030673 (rank : 138)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZV9, Q4V758	Gene names	FGF23, HYPF
Domain Architecture
Description	Fibroblast growth factor 23 precursor (FGF-23) (Tumor-derived hypophosphatemia-inducing factor).

OXR1_MOUSE
NC score	0.030608 (rank : 139)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	516	Shared Neighborhood Hits	14
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

CEBPE_HUMAN
NC score	0.030426 (rank : 140)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

IWS1_HUMAN
NC score	0.029488 (rank : 141)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	1241	Shared Neighborhood Hits	19
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DTNA_MOUSE
NC score	0.029414 (rank : 142)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	264	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D2N4, P97319, Q61498, Q61499, Q9QZZ5, Q9WUL9, Q9WUM0	Gene names	Dtna, Dtn
Domain Architecture
Description	Dystrobrevin alpha (Alpha-dystrobrevin).

FA21C_HUMAN
NC score	0.028903 (rank : 143)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

SDC2_MOUSE
NC score	0.028242 (rank : 144)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P43407	Gene names	Sdc2, Hspg1, Synd2
Domain Architecture
Description	Syndecan-2 precursor (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG).

TTC14_HUMAN
NC score	0.027540 (rank : 145)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

FBX38_HUMAN
NC score	0.026571 (rank : 146)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

TARA_HUMAN
NC score	0.025919 (rank : 147)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	1626	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RBBP6_HUMAN
NC score	0.025862 (rank : 148)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	1135	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

STX18_HUMAN
NC score	0.024782 (rank : 149)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

ATRX_HUMAN
NC score	0.024647 (rank : 150)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	842	Shared Neighborhood Hits	22
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

TRHY_HUMAN
NC score	0.022462 (rank : 151)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	1385	Shared Neighborhood Hits	37
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CCD91_HUMAN
NC score	0.022267 (rank : 152)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	868	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

DHX16_HUMAN
NC score	0.022009 (rank : 153)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

TARA_MOUSE
NC score	0.021731 (rank : 154)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	1133	Shared Neighborhood Hits	21
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LPIN1_MOUSE
NC score	0.021717 (rank : 155)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZP3, Q9CQI2, Q9JLG6	Gene names	Lpin1, Fld
Domain Architecture
Description	Lipin-1 (Fatty liver dystrophy protein).

REN3B_HUMAN
NC score	0.021557 (rank : 156)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	412	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

DACT1_HUMAN
NC score	0.020748 (rank : 157)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

NEMO_HUMAN
NC score	0.018948 (rank : 158)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	820	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

KIF3A_HUMAN
NC score	0.018803 (rank : 159)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	704	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

ZFYV1_HUMAN
NC score	0.018547 (rank : 160)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

NFH_MOUSE
NC score	0.018350 (rank : 161)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	2247	Shared Neighborhood Hits	42
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

K0056_HUMAN
NC score	0.016648 (rank : 162)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

CEBPA_HUMAN
NC score	0.016488 (rank : 163)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

SAFB2_HUMAN
NC score	0.016467 (rank : 164)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	720	Shared Neighborhood Hits	17
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

CEBPA_MOUSE
NC score	0.016298 (rank : 165)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

SNX23_HUMAN
NC score	0.015966 (rank : 166)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	944	Shared Neighborhood Hits	17
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

BAZ2A_HUMAN
NC score	0.015699 (rank : 167)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	780	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CP250_MOUSE
NC score	0.015380 (rank : 168)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	1583	Shared Neighborhood Hits	30
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

JHD2C_HUMAN
NC score	0.014335 (rank : 169)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

KLRA2_MOUSE
NC score	0.013892 (rank : 170)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q60660	Gene names	Klra2, Ly49-b, Ly49b
Domain Architecture
Description	Killer cell lectin-like receptor 2 (T-cell surface glycoprotein Ly- 49B) (Ly49-B antigen) (Lymphocyte antigen 49B).

NUFP1_MOUSE
NC score	0.013107 (rank : 171)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXX8, Q9CV69	Gene names	Nufip1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

NUP88_MOUSE
NC score	0.012654 (rank : 172)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	239	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

GP149_HUMAN
NC score	0.009945 (rank : 173)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

INCE_MOUSE
NC score	0.009912 (rank : 174)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	903	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

MY18A_MOUSE
NC score	0.009600 (rank : 175)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	1989	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CROCC_HUMAN
NC score	0.009427 (rank : 176)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	1409	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGA1_MOUSE
NC score	0.007526 (rank : 177)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	994	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MAST4_HUMAN
NC score	-0.000510 (rank : 178)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	1804	Shared Neighborhood Hits	24
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PTPRD_HUMAN
NC score	-0.000931 (rank : 179)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	485	Shared Neighborhood Hits	2
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

MTR1L_HUMAN
NC score	-0.003242 (rank : 180)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	1180	Shared Neighborhood Hits	8
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).