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Network neighborhood for query Sequence : MYCN_MOUSE

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MYCN_MOUSE
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MYCN_MOUSE
θ value	1.41267e-170 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
θ value	4.72459e-150 (rank : 2)	NC score	0.981433 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	127	Shared Neighborhood Hits	86
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
θ value	3.54468e-105 (rank : 3)	NC score	0.955323 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYC_MOUSE
θ value	3.06405e-32 (rank : 4)	NC score	0.827098 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
θ value	3.3877e-31 (rank : 5)	NC score	0.820753 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	56
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCL1_HUMAN
θ value	2.27234e-27 (rank : 6)	NC score	0.783242 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	58
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
θ value	4.43474e-23 (rank : 7)	NC score	0.745339 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	63	Shared Neighborhood Hits	38
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYCL1_MOUSE
θ value	5.07402e-19 (rank : 8)	NC score	0.743898 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	123	Shared Neighborhood Hits	55
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCB_MOUSE
θ value	1.86753e-13 (rank : 9)	NC score	0.694378 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MAX_HUMAN
θ value	3.64472e-09 (rank : 10)	NC score	0.617499 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
θ value	1.06045e-08 (rank : 11)	NC score	0.610014 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

FIGLA_MOUSE
θ value	4.92598e-06 (rank : 12)	NC score	0.348104 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

SRBP2_HUMAN
θ value	9.29e-05 (rank : 13)	NC score	0.289726 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	133	Shared Neighborhood Hits	40
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

MNT_HUMAN
θ value	0.000158464 (rank : 14)	NC score	0.303043 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	496	Shared Neighborhood Hits	54
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	0.00020696 (rank : 15)	NC score	0.310508 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	432	Shared Neighborhood Hits	50
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

FIGLA_HUMAN
θ value	0.00035302 (rank : 16)	NC score	0.331455 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	108	Shared Neighborhood Hits	43
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

ASCL1_HUMAN
θ value	0.00102713 (rank : 17)	NC score	0.269784 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

USF1_HUMAN
θ value	0.00102713 (rank : 18)	NC score	0.351928 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.00102713 (rank : 19)	NC score	0.354385 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

ASCL1_MOUSE
θ value	0.00228821 (rank : 20)	NC score	0.256316 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	97	Shared Neighborhood Hits	34
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

MITF_HUMAN
θ value	0.00228821 (rank : 21)	NC score	0.276061 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	41
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

USF2_HUMAN
θ value	0.00228821 (rank : 22)	NC score	0.352257 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	155	Shared Neighborhood Hits	51
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.00228821 (rank : 23)	NC score	0.349090 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MITF_MOUSE
θ value	0.00390308 (rank : 24)	NC score	0.273746 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	42
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MAD1_MOUSE
θ value	0.00869519 (rank : 25)	NC score	0.213767 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	75	Shared Neighborhood Hits	35
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD4_HUMAN
θ value	0.0113563 (rank : 26)	NC score	0.290986 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

ASCL2_MOUSE
θ value	0.0193708 (rank : 27)	NC score	0.241067 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

PTF1A_MOUSE
θ value	0.0193708 (rank : 28)	NC score	0.196020 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

SRBP1_HUMAN
θ value	0.0193708 (rank : 29)	NC score	0.253470 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	43
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

BHLH8_HUMAN
θ value	0.0252991 (rank : 30)	NC score	0.246360 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_MOUSE
θ value	0.0252991 (rank : 31)	NC score	0.255069 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

CBX2_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.047900 (rank : 134)
Query Neighborhood Hits	125	Target Neighborhood Hits	264	Shared Neighborhood Hits	7
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

MXI1_MOUSE
θ value	0.0431538 (rank : 33)	NC score	0.304409 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

TFAP4_HUMAN
θ value	0.0431538 (rank : 34)	NC score	0.307312 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	289	Shared Neighborhood Hits	51
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

TFE3_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.278323 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	190	Shared Neighborhood Hits	46
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

NDF2_HUMAN
θ value	0.0563607 (rank : 36)	NC score	0.129453 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	0.0563607 (rank : 37)	NC score	0.129310 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	35
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

SRBP1_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.238206 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	384	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ASCL2_HUMAN
θ value	0.0736092 (rank : 39)	NC score	0.205623 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

MAD4_MOUSE
θ value	0.0736092 (rank : 40)	NC score	0.241276 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	65	Shared Neighborhood Hits	25
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

ASCL3_HUMAN
θ value	0.0961366 (rank : 41)	NC score	0.187848 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

MLX_HUMAN
θ value	0.0961366 (rank : 42)	NC score	0.253691 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	0.0961366 (rank : 43)	NC score	0.255636 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MXI1_HUMAN
θ value	0.163984 (rank : 44)	NC score	0.291799 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

NFH_MOUSE
θ value	0.163984 (rank : 45)	NC score	0.026495 (rank : 143)
Query Neighborhood Hits	125	Target Neighborhood Hits	2247	Shared Neighborhood Hits	37
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PTF1A_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.192966 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

ARNT2_HUMAN
θ value	0.21417 (rank : 47)	NC score	0.124522 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	0.21417 (rank : 48)	NC score	0.124979 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	33
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_HUMAN
θ value	0.21417 (rank : 49)	NC score	0.137061 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	0.21417 (rank : 50)	NC score	0.132797 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	213	Shared Neighborhood Hits	36
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ASCL3_MOUSE
θ value	0.279714 (rank : 51)	NC score	0.173938 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

HGS_MOUSE
θ value	0.365318 (rank : 52)	NC score	0.027703 (rank : 141)
Query Neighborhood Hits	125	Target Neighborhood Hits	589	Shared Neighborhood Hits	24
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HAND2_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.201774 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.201774 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

NGN3_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.125341 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

OSBP2_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.021909 (rank : 146)
Query Neighborhood Hits	125	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

SDPR_MOUSE
θ value	0.47712 (rank : 57)	NC score	0.033298 (rank : 138)
Query Neighborhood Hits	125	Target Neighborhood Hits	485	Shared Neighborhood Hits	14
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

TFEB_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.222917 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

HAND1_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.173198 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

HAND1_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.178320 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	39
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

ITF2_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.078589 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	168	Shared Neighborhood Hits	25
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.079760 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	154	Shared Neighborhood Hits	26
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

TFEB_HUMAN
θ value	0.62314 (rank : 63)	NC score	0.221242 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	39
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

SPIB_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.032528 (rank : 139)
Query Neighborhood Hits	125	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

HTF4_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.071748 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

FGD5_HUMAN
θ value	1.38821 (rank : 66)	NC score	0.015714 (rank : 161)
Query Neighborhood Hits	125	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

HTF4_MOUSE
θ value	1.38821 (rank : 67)	NC score	0.070801 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	153	Shared Neighborhood Hits	22
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

ID1_HUMAN
θ value	1.38821 (rank : 68)	NC score	0.120636 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID1_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.118358 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

MUC1_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.016695 (rank : 158)
Query Neighborhood Hits	125	Target Neighborhood Hits	975	Shared Neighborhood Hits	18
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SMBP2_HUMAN
θ value	1.38821 (rank : 71)	NC score	0.019593 (rank : 154)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

CSF1_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.023264 (rank : 144)
Query Neighborhood Hits	125	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

MYH6_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.012790 (rank : 173)
Query Neighborhood Hits	125	Target Neighborhood Hits	1426	Shared Neighborhood Hits	22
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CIC_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.019533 (rank : 155)
Query Neighborhood Hits	125	Target Neighborhood Hits	992	Shared Neighborhood Hits	24
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DOCK6_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.015477 (rank : 165)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

GATA6_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.012902 (rank : 172)
Query Neighborhood Hits	125	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q92908, P78327	Gene names	GATA6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

GDIA_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.040669 (rank : 135)
Query Neighborhood Hits	125	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P31150, P50394, Q7Z2G6, Q7Z2G9, Q7Z2H5, Q7Z2I6	Gene names	GDI1, OPHN2, RABGDIA, XAP4
Domain Architecture
Description	Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (XAP-4) (Oligophrenin- 2).

MYH6_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.012193 (rank : 179)
Query Neighborhood Hits	125	Target Neighborhood Hits	1501	Shared Neighborhood Hits	25
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

SFRIP_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.020880 (rank : 153)
Query Neighborhood Hits	125	Target Neighborhood Hits	530	Shared Neighborhood Hits	7
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

ANK3_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.003311 (rank : 188)
Query Neighborhood Hits	125	Target Neighborhood Hits	853	Shared Neighborhood Hits	10
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

MAD3_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.257458 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.250521 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAGE1_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.014294 (rank : 170)
Query Neighborhood Hits	125	Target Neighborhood Hits	1389	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MYH7_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.012709 (rank : 175)
Query Neighborhood Hits	125	Target Neighborhood Hits	1559	Shared Neighborhood Hits	23
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PODXL_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.027458 (rank : 142)
Query Neighborhood Hits	125	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

RL7_MOUSE
θ value	3.0926 (rank : 86)	NC score	0.021425 (rank : 151)
Query Neighborhood Hits	125	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P14148, Q80UR0	Gene names	Rpl7
Domain Architecture
Description	60S ribosomal protein L7.

ATOH1_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.124728 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
θ value	4.03905 (rank : 88)	NC score	0.124503 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

EP300_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.012712 (rank : 174)
Query Neighborhood Hits	125	Target Neighborhood Hits	821	Shared Neighborhood Hits	19
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GDIA_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.037586 (rank : 136)
Query Neighborhood Hits	125	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	P50396, Q8VHM3, Q91Y71, Q96CX5	Gene names	Gdi1, Rabgdia
Domain Architecture
Description	Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1).

GDIB_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.037273 (rank : 137)
Query Neighborhood Hits	125	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q61598, Q541Z9, Q8C530, Q9D8M9	Gene names	Gdi2, Gdi3
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2) (GDI-3).

SMC4_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.014371 (rank : 169)
Query Neighborhood Hits	125	Target Neighborhood Hits	937	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

WNK4_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.000651 (rank : 190)
Query Neighborhood Hits	125	Target Neighborhood Hits	1043	Shared Neighborhood Hits	11
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

CASP_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.015318 (rank : 166)
Query Neighborhood Hits	125	Target Neighborhood Hits	1152	Shared Neighborhood Hits	18
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CENPE_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.008525 (rank : 183)
Query Neighborhood Hits	125	Target Neighborhood Hits	2060	Shared Neighborhood Hits	33
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CUTL1_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.016564 (rank : 159)
Query Neighborhood Hits	125	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

GAK11_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.021588 (rank : 149)
Query Neighborhood Hits	125	Target Neighborhood Hits	409	Shared Neighborhood Hits	11
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.022012 (rank : 145)
Query Neighborhood Hits	125	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.021519 (rank : 150)
Query Neighborhood Hits	125	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.021595 (rank : 148)
Query Neighborhood Hits	125	Target Neighborhood Hits	415	Shared Neighborhood Hits	11
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.021726 (rank : 147)
Query Neighborhood Hits	125	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RHG05_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.015825 (rank : 160)
Query Neighborhood Hits	125	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.015490 (rank : 163)
Query Neighborhood Hits	125	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SRCA_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.012508 (rank : 176)
Query Neighborhood Hits	125	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TEF_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.017310 (rank : 157)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q10587, Q15729, Q7Z3J7, Q8IU94, Q96TG4	Gene names	TEF
Domain Architecture
Description	Thyrotroph embryonic factor.

TEF_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.017371 (rank : 156)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLC6, Q3U426, Q3UGF4, Q3UM49, Q3URC8, Q6QHT6, Q8C6I0, Q8VD02	Gene names	Tef
Domain Architecture	No domain graphic available
Description	Thyrotroph embryonic factor.

TTLL4_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.011904 (rank : 180)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

BHLH2_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.058043 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.058932 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

CASP_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.015042 (rank : 168)
Query Neighborhood Hits	125	Target Neighborhood Hits	1131	Shared Neighborhood Hits	20
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CEBPB_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.015256 (rank : 167)
Query Neighborhood Hits	125	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	P17676, Q96IH2, Q9H4Z5	Gene names	CEBPB, TCF5
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF- IL6) (Transcription factor 5).

CUTL1_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.015480 (rank : 164)
Query Neighborhood Hits	125	Target Neighborhood Hits	1574	Shared Neighborhood Hits	22
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GAK10_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.021065 (rank : 152)
Query Neighborhood Hits	125	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ACINU_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.029409 (rank : 140)
Query Neighborhood Hits	125	Target Neighborhood Hits	828	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ALS2_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.006039 (rank : 184)
Query Neighborhood Hits	125	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ARID2_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.013005 (rank : 171)
Query Neighborhood Hits	125	Target Neighborhood Hits	302	Shared Neighborhood Hits	6
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

EPN1_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.015490 (rank : 162)
Query Neighborhood Hits	125	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

ETV3_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.009200 (rank : 182)
Query Neighborhood Hits	125	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

KCNC4_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.002199 (rank : 189)
Query Neighborhood Hits	125	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KI21A_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.005884 (rank : 185)
Query Neighborhood Hits	125	Target Neighborhood Hits	1543	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KI21A_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.005660 (rank : 186)
Query Neighborhood Hits	125	Target Neighborhood Hits	1317	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

PEPL_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.010361 (rank : 181)
Query Neighborhood Hits	125	Target Neighborhood Hits	1105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

SNPC2_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.012224 (rank : 178)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

TRIPB_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.012505 (rank : 177)
Query Neighborhood Hits	125	Target Neighborhood Hits	1587	Shared Neighborhood Hits	30
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

UN45B_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.005548 (rank : 187)
Query Neighborhood Hits	125	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGY6, Q5XG72, Q8BHC5, Q8BWK3	Gene names	Unc45b, Cmya4
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

BHLH3_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.060665 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	106	Shared Neighborhood Hits	31
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.056521 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BHLH4_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.060230 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BHLH4_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.058934 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BMAL1_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.077291 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	37
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.076843 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

HEN1_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.096454 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN1_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.098501 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.096150 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.095343 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEY1_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.051248 (rank : 132)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.052266 (rank : 130)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.054905 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.055286 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

ID2_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.056832 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	Q02363	Gene names	ID2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

ID2_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.051398 (rank : 131)
Query Neighborhood Hits	125	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P41136, O88604	Gene names	Id2, Id-2, Idb2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

ID4_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.067031 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	P47928, Q13005	Gene names	ID4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

ID4_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.065074 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	66	Shared Neighborhood Hits	24
SwissProt Accessions	P41139	Gene names	Id4, Id-4, Idb4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

LYL1_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.098179 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

LYL1_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.099619 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

MAD1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.148387 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	28
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MUSC_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.076416 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

MUSC_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.077565 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MYF5_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.080908 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	33
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF5_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.082805 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF6_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.093267 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.089169 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

MYOD1_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.076754 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	31
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MYOD1_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.079363 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MYOG_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.088485 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.089004 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

NDF1_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.085768 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	186	Shared Neighborhood Hits	36
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF1_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.086968 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	209	Shared Neighborhood Hits	36
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF4_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.070677 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

NDF4_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.071490 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

NDF6_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.072073 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	91	Shared Neighborhood Hits	27
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.071980 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

NGN1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.080574 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

NGN1_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.082063 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

NGN2_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.100614 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN2_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.100723 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NGN3_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.101833 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

OLIG1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.054883 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OLIG1_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.054573 (rank : 129)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

OLIG2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.058995 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	84	Shared Neighborhood Hits	24
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.058208 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

OLIG3_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.055038 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

OLIG3_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.055870 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

SCX_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.132803 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	29
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

TAL1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.106953 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

TAL1_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.108605 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL2_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.092043 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

TAL2_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.091326 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

TCF15_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.094324 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

TCF15_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.098358 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	26
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

TCF21_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.072496 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.071623 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCFL5_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.062015 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFE2_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.050357 (rank : 133)
Query Neighborhood Hits	125	Target Neighborhood Hits	161	Shared Neighborhood Hits	22
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

TWST1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.141529 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.141388 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

TWST2_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.142476 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.142469 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

WBS14_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.132359 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	273	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WBS14_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.083322 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

Hits sorted by NC score

MYCN_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.41267e-170 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.981433 (rank : 2)	θ value	4.72459e-150 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	127	Shared Neighborhood Hits	86
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
NC score	0.955323 (rank : 3)	θ value	3.54468e-105 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYC_MOUSE
NC score	0.827098 (rank : 4)	θ value	3.06405e-32 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
NC score	0.820753 (rank : 5)	θ value	3.3877e-31 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	56
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCL1_HUMAN
NC score	0.783242 (rank : 6)	θ value	2.27234e-27 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	146	Shared Neighborhood Hits	58
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
NC score	0.745339 (rank : 7)	θ value	4.43474e-23 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	63	Shared Neighborhood Hits	38
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYCL1_MOUSE
NC score	0.743898 (rank : 8)	θ value	5.07402e-19 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	123	Shared Neighborhood Hits	55
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCB_MOUSE
NC score	0.694378 (rank : 9)	θ value	1.86753e-13 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MAX_HUMAN
NC score	0.617499 (rank : 10)	θ value	3.64472e-09 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
NC score	0.610014 (rank : 11)	θ value	1.06045e-08 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

USF1_MOUSE
NC score	0.354385 (rank : 12)	θ value	0.00102713 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.352257 (rank : 13)	θ value	0.00228821 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	155	Shared Neighborhood Hits	51
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF1_HUMAN
NC score	0.351928 (rank : 14)	θ value	0.00102713 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_MOUSE
NC score	0.349090 (rank : 15)	θ value	0.00228821 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

FIGLA_MOUSE
NC score	0.348104 (rank : 16)	θ value	4.92598e-06 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

FIGLA_HUMAN
NC score	0.331455 (rank : 17)	θ value	0.00035302 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	108	Shared Neighborhood Hits	43
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MNT_MOUSE
NC score	0.310508 (rank : 18)	θ value	0.00020696 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	432	Shared Neighborhood Hits	50
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

TFAP4_HUMAN
NC score	0.307312 (rank : 19)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	289	Shared Neighborhood Hits	51
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

MXI1_MOUSE
NC score	0.304409 (rank : 20)	θ value	0.0431538 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MNT_HUMAN
NC score	0.303043 (rank : 21)	θ value	0.000158464 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	496	Shared Neighborhood Hits	54
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MXI1_HUMAN
NC score	0.291799 (rank : 22)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD4_HUMAN
NC score	0.290986 (rank : 23)	θ value	0.0113563 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

SRBP2_HUMAN
NC score	0.289726 (rank : 24)	θ value	9.29e-05 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	133	Shared Neighborhood Hits	40
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

TFE3_HUMAN
NC score	0.278323 (rank : 25)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	190	Shared Neighborhood Hits	46
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_HUMAN
NC score	0.276061 (rank : 26)	θ value	0.00228821 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	41
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.273746 (rank : 27)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	42
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

ASCL1_HUMAN
NC score	0.269784 (rank : 28)	θ value	0.00102713 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

MAD3_HUMAN
NC score	0.257458 (rank : 29)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

ASCL1_MOUSE
NC score	0.256316 (rank : 30)	θ value	0.00228821 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	97	Shared Neighborhood Hits	34
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

MLX_MOUSE
NC score	0.255636 (rank : 31)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

BHLH8_MOUSE
NC score	0.255069 (rank : 32)	θ value	0.0252991 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MLX_HUMAN
NC score	0.253691 (rank : 33)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

SRBP1_HUMAN
NC score	0.253470 (rank : 34)	θ value	0.0193708 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	43
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MAD3_MOUSE
NC score	0.250521 (rank : 35)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

BHLH8_HUMAN
NC score	0.246360 (rank : 36)	θ value	0.0252991 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MAD4_MOUSE
NC score	0.241276 (rank : 37)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	65	Shared Neighborhood Hits	25
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

ASCL2_MOUSE
NC score	0.241067 (rank : 38)	θ value	0.0193708 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

SRBP1_MOUSE
NC score	0.238206 (rank : 39)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	384	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TFEB_MOUSE
NC score	0.222917 (rank : 40)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.221242 (rank : 41)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	39
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

MAD1_MOUSE
NC score	0.213767 (rank : 42)	θ value	0.00869519 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	75	Shared Neighborhood Hits	35
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

ASCL2_HUMAN
NC score	0.205623 (rank : 43)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

HAND2_HUMAN
NC score	0.201774 (rank : 44)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
NC score	0.201774 (rank : 45)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

PTF1A_MOUSE
NC score	0.196020 (rank : 46)	θ value	0.0193708 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

PTF1A_HUMAN
NC score	0.192966 (rank : 47)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

ASCL3_HUMAN
NC score	0.187848 (rank : 48)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

HAND1_MOUSE
NC score	0.178320 (rank : 49)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	39
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

ASCL3_MOUSE
NC score	0.173938 (rank : 50)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

HAND1_HUMAN
NC score	0.173198 (rank : 51)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

MAD1_HUMAN
NC score	0.148387 (rank : 52)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	28
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

TWST2_HUMAN
NC score	0.142476 (rank : 53)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
NC score	0.142469 (rank : 54)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST1_HUMAN
NC score	0.141529 (rank : 55)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	125	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
NC score	0.141388 (rank : 56)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	125	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

ARNT_HUMAN
NC score	0.137061 (rank : 57)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

SCX_MOUSE
NC score	0.132803 (rank : 58)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	29
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

ARNT_MOUSE
NC score	0.132797 (rank : 59)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	213	Shared Neighborhood Hits	36
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

WBS14_HUMAN
NC score	0.132359 (rank : 60)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	125	Target Neighborhood Hits	273	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

NDF2_HUMAN
NC score	0.129453 (rank : 61)	θ value	0.0563607 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
NC score	0.129310 (rank : 62)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	35
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NGN3_HUMAN
NC score	0.125341 (rank : 63)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

ARNT2_MOUSE
NC score	0.124979 (rank : 64)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	33
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ATOH1_HUMAN
NC score	0.124728 (rank : 65)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ARNT2_HUMAN
NC score	0.124522 (rank : 66)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ATOH1_MOUSE
NC score	0.124503 (rank : 67)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

ID1_HUMAN
NC score	0.120636 (rank : 68)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID1_MOUSE
NC score	0.118358 (rank : 69)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

TAL1_MOUSE
NC score	0.108605 (rank : 70)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	125	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL1_HUMAN
NC score	0.106953 (rank : 71)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	125	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

NGN3_MOUSE
NC score	0.101833 (rank : 72)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	125	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

NGN2_MOUSE
NC score	0.100723 (rank : 73)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	125	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NGN2_HUMAN
NC score	0.100614 (rank : 74)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	125	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

LYL1_MOUSE
NC score	0.099619 (rank : 75)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	125	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

HEN1_MOUSE
NC score	0.098501 (rank : 76)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	125	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

TCF15_MOUSE
NC score	0.098358 (rank : 77)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	26
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

LYL1_HUMAN
NC score	0.098179 (rank : 78)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	125	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

HEN1_HUMAN
NC score	0.096454 (rank : 79)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	125	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
NC score	0.096150 (rank : 80)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
NC score	0.095343 (rank : 81)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

TCF15_HUMAN
NC score	0.094324 (rank : 82)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

MYF6_HUMAN
NC score	0.093267 (rank : 83)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

TAL2_HUMAN
NC score	0.092043 (rank : 84)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

TAL2_MOUSE
NC score	0.091326 (rank : 85)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

MYF6_MOUSE
NC score	0.089169 (rank : 86)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

MYOG_MOUSE
NC score	0.089004 (rank : 87)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

MYOG_HUMAN
NC score	0.088485 (rank : 88)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

NDF1_MOUSE
NC score	0.086968 (rank : 89)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	125	Target Neighborhood Hits	209	Shared Neighborhood Hits	36
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF1_HUMAN
NC score	0.085768 (rank : 90)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	125	Target Neighborhood Hits	186	Shared Neighborhood Hits	36
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

WBS14_MOUSE
NC score	0.083322 (rank : 91)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	125	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

MYF5_MOUSE
NC score	0.082805 (rank : 92)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

NGN1_MOUSE
NC score	0.082063 (rank : 93)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	125	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

MYF5_HUMAN
NC score	0.080908 (rank : 94)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	33
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

NGN1_HUMAN
NC score	0.080574 (rank : 95)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

ITF2_MOUSE
NC score	0.079760 (rank : 96)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	154	Shared Neighborhood Hits	26
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

MYOD1_MOUSE
NC score	0.079363 (rank : 97)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

ITF2_HUMAN
NC score	0.078589 (rank : 98)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	168	Shared Neighborhood Hits	25
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

MUSC_MOUSE
NC score	0.077565 (rank : 99)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

BMAL1_HUMAN
NC score	0.077291 (rank : 100)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	125	Target Neighborhood Hits	115	Shared Neighborhood Hits	37
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.076843 (rank : 101)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	125	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

MYOD1_HUMAN
NC score	0.076754 (rank : 102)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	125	Target Neighborhood Hits	100	Shared Neighborhood Hits	31
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MUSC_HUMAN
NC score	0.076416 (rank : 103)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	125	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

TCF21_HUMAN
NC score	0.072496 (rank : 104)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

NDF6_HUMAN
NC score	0.072073 (rank : 105)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	125	Target Neighborhood Hits	91	Shared Neighborhood Hits	27
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
NC score	0.071980 (rank : 106)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	125	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

HTF4_HUMAN
NC score	0.071748 (rank : 107)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

TCF21_MOUSE
NC score	0.071623 (rank : 108)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

NDF4_MOUSE
NC score	0.071490 (rank : 109)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	125	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

HTF4_MOUSE
NC score	0.070801 (rank : 110)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	153	Shared Neighborhood Hits	22
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

NDF4_HUMAN
NC score	0.070677 (rank : 111)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	125	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

ID4_HUMAN
NC score	0.067031 (rank : 112)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	125	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	P47928, Q13005	Gene names	ID4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

ID4_MOUSE
NC score	0.065074 (rank : 113)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	125	Target Neighborhood Hits	66	Shared Neighborhood Hits	24
SwissProt Accessions	P41139	Gene names	Id4, Id-4, Idb4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

TCFL5_HUMAN
NC score	0.062015 (rank : 114)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	125	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

BHLH3_HUMAN
NC score	0.060665 (rank : 115)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	106	Shared Neighborhood Hits	31
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH4_HUMAN
NC score	0.060230 (rank : 116)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

OLIG2_HUMAN
NC score	0.058995 (rank : 117)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	125	Target Neighborhood Hits	84	Shared Neighborhood Hits	24
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

BHLH4_MOUSE
NC score	0.058934 (rank : 118)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BHLH2_MOUSE
NC score	0.058932 (rank : 119)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

OLIG2_MOUSE
NC score	0.058208 (rank : 120)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	125	Target Neighborhood Hits	74	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

BHLH2_HUMAN
NC score	0.058043 (rank : 121)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

ID2_HUMAN
NC score	0.056832 (rank : 122)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	125	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	Q02363	Gene names	ID2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

BHLH3_MOUSE
NC score	0.056521 (rank : 123)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

OLIG3_MOUSE
NC score	0.055870 (rank : 124)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

HEY2_MOUSE
NC score	0.055286 (rank : 125)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

OLIG3_HUMAN
NC score	0.055038 (rank : 126)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

HEY2_HUMAN
NC score	0.054905 (rank : 127)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

OLIG1_HUMAN
NC score	0.054883 (rank : 128)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OLIG1_MOUSE
NC score	0.054573 (rank : 129)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

HEY1_MOUSE
NC score	0.052266 (rank : 130)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	125	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

ID2_MOUSE
NC score	0.051398 (rank : 131)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	125	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P41136, O88604	Gene names	Id2, Id-2, Idb2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

HEY1_HUMAN
NC score	0.051248 (rank : 132)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

TFE2_HUMAN
NC score	0.050357 (rank : 133)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	125	Target Neighborhood Hits	161	Shared Neighborhood Hits	22
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

CBX2_HUMAN
NC score	0.047900 (rank : 134)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	264	Shared Neighborhood Hits	7
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

GDIA_HUMAN
NC score	0.040669 (rank : 135)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P31150, P50394, Q7Z2G6, Q7Z2G9, Q7Z2H5, Q7Z2I6	Gene names	GDI1, OPHN2, RABGDIA, XAP4
Domain Architecture
Description	Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (XAP-4) (Oligophrenin- 2).

GDIA_MOUSE
NC score	0.037586 (rank : 136)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	P50396, Q8VHM3, Q91Y71, Q96CX5	Gene names	Gdi1, Rabgdia
Domain Architecture
Description	Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1).

GDIB_MOUSE
NC score	0.037273 (rank : 137)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q61598, Q541Z9, Q8C530, Q9D8M9	Gene names	Gdi2, Gdi3
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2) (GDI-3).

SDPR_MOUSE
NC score	0.033298 (rank : 138)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	485	Shared Neighborhood Hits	14
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SPIB_MOUSE
NC score	0.032528 (rank : 139)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

ACINU_HUMAN
NC score	0.029409 (rank : 140)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	828	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

HGS_MOUSE
NC score	0.027703 (rank : 141)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	589	Shared Neighborhood Hits	24
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

PODXL_HUMAN
NC score	0.027458 (rank : 142)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

NFH_MOUSE
NC score	0.026495 (rank : 143)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	2247	Shared Neighborhood Hits	37
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CSF1_HUMAN
NC score	0.023264 (rank : 144)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

GAK12_HUMAN
NC score	0.022012 (rank : 145)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

OSBP2_HUMAN
NC score	0.021909 (rank : 146)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

GAK6_HUMAN
NC score	0.021726 (rank : 147)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.021595 (rank : 148)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	415	Shared Neighborhood Hits	11
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.021588 (rank : 149)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	409	Shared Neighborhood Hits	11
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.021519 (rank : 150)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RL7_MOUSE
NC score	0.021425 (rank : 151)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P14148, Q80UR0	Gene names	Rpl7
Domain Architecture
Description	60S ribosomal protein L7.

GAK10_HUMAN
NC score	0.021065 (rank : 152)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SFRIP_HUMAN
NC score	0.020880 (rank : 153)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	530	Shared Neighborhood Hits	7
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SMBP2_HUMAN
NC score	0.019593 (rank : 154)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

CIC_HUMAN
NC score	0.019533 (rank : 155)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	992	Shared Neighborhood Hits	24
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TEF_MOUSE
NC score	0.017371 (rank : 156)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLC6, Q3U426, Q3UGF4, Q3UM49, Q3URC8, Q6QHT6, Q8C6I0, Q8VD02	Gene names	Tef
Domain Architecture	No domain graphic available
Description	Thyrotroph embryonic factor.

TEF_HUMAN
NC score	0.017310 (rank : 157)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q10587, Q15729, Q7Z3J7, Q8IU94, Q96TG4	Gene names	TEF
Domain Architecture
Description	Thyrotroph embryonic factor.

MUC1_HUMAN
NC score	0.016695 (rank : 158)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	975	Shared Neighborhood Hits	18
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CUTL1_MOUSE
NC score	0.016564 (rank : 159)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

RHG05_HUMAN
NC score	0.015825 (rank : 160)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

FGD5_HUMAN
NC score	0.015714 (rank : 161)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

EPN1_HUMAN
NC score	0.015490 (rank : 162)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

RHG05_MOUSE
NC score	0.015490 (rank : 163)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CUTL1_HUMAN
NC score	0.015480 (rank : 164)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	1574	Shared Neighborhood Hits	22
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DOCK6_HUMAN
NC score	0.015477 (rank : 165)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

CASP_MOUSE
NC score	0.015318 (rank : 166)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	1152	Shared Neighborhood Hits	18
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CEBPB_HUMAN
NC score	0.015256 (rank : 167)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	P17676, Q96IH2, Q9H4Z5	Gene names	CEBPB, TCF5
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF- IL6) (Transcription factor 5).

CASP_HUMAN
NC score	0.015042 (rank : 168)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	1131	Shared Neighborhood Hits	20
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

SMC4_HUMAN
NC score	0.014371 (rank : 169)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	937	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

MAGE1_HUMAN
NC score	0.014294 (rank : 170)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	1389	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ARID2_HUMAN
NC score	0.013005 (rank : 171)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	302	Shared Neighborhood Hits	6
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

GATA6_HUMAN
NC score	0.012902 (rank : 172)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q92908, P78327	Gene names	GATA6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

MYH6_HUMAN
NC score	0.012790 (rank : 173)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	1426	Shared Neighborhood Hits	22
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

EP300_HUMAN
NC score	0.012712 (rank : 174)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	821	Shared Neighborhood Hits	19
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MYH7_HUMAN
NC score	0.012709 (rank : 175)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	1559	Shared Neighborhood Hits	23
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

SRCA_MOUSE
NC score	0.012508 (rank : 176)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TRIPB_HUMAN
NC score	0.012505 (rank : 177)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	1587	Shared Neighborhood Hits	30
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

SNPC2_MOUSE
NC score	0.012224 (rank : 178)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

MYH6_MOUSE
NC score	0.012193 (rank : 179)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	1501	Shared Neighborhood Hits	25
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

TTLL4_HUMAN
NC score	0.011904 (rank : 180)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

PEPL_MOUSE
NC score	0.010361 (rank : 181)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	1105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

ETV3_HUMAN
NC score	0.009200 (rank : 182)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

CENPE_HUMAN
NC score	0.008525 (rank : 183)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	2060	Shared Neighborhood Hits	33
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

ALS2_HUMAN
NC score	0.006039 (rank : 184)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

KI21A_HUMAN
NC score	0.005884 (rank : 185)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	1543	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KI21A_MOUSE
NC score	0.005660 (rank : 186)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	1317	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

UN45B_MOUSE
NC score	0.005548 (rank : 187)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGY6, Q5XG72, Q8BHC5, Q8BWK3	Gene names	Unc45b, Cmya4
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

ANK3_HUMAN
NC score	0.003311 (rank : 188)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	853	Shared Neighborhood Hits	10
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

KCNC4_HUMAN
NC score	0.002199 (rank : 189)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

WNK4_HUMAN
NC score	0.000651 (rank : 190)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	1043	Shared Neighborhood Hits	11
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).