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Network neighborhood for query Sequence : MAD4_MOUSE

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MAD4_MOUSE
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MAD4_MOUSE
θ value	8.75112e-96 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD4_HUMAN
θ value	1.22395e-89 (rank : 2)	NC score	0.974956 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD1_MOUSE
θ value	5.39604e-37 (rank : 3)	NC score	0.919926 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_HUMAN
θ value	3.4976e-36 (rank : 4)	NC score	0.919669 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MXI1_MOUSE
θ value	1.12514e-34 (rank : 5)	NC score	0.914988 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
θ value	2.77131e-33 (rank : 6)	NC score	0.919582 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD3_HUMAN
θ value	5.06226e-27 (rank : 7)	NC score	0.891616 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	1.24688e-25 (rank : 8)	NC score	0.892869 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MNT_MOUSE
θ value	4.1701e-05 (rank : 9)	NC score	0.431531 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	432	Shared Neighborhood Hits	32
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
θ value	7.1131e-05 (rank : 10)	NC score	0.413792 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	496	Shared Neighborhood Hits	33
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

RPC5_HUMAN
θ value	0.000602161 (rank : 11)	NC score	0.125750 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVU0, Q9BWF7, Q9H8W8, Q9H907, Q9P276	Gene names	POLR3E, KIAA1452
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5).

MYC_HUMAN
θ value	0.00228821 (rank : 12)	NC score	0.313785 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	146	Shared Neighborhood Hits	26
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_MOUSE
θ value	0.00228821 (rank : 13)	NC score	0.318226 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	23
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCL2_HUMAN
θ value	0.0148317 (rank : 14)	NC score	0.276291 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	17
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

USF2_HUMAN
θ value	0.0193708 (rank : 15)	NC score	0.275535 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	155	Shared Neighborhood Hits	33
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.0193708 (rank : 16)	NC score	0.275052 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	173	Shared Neighborhood Hits	33
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MYCN_HUMAN
θ value	0.0330416 (rank : 17)	NC score	0.238531 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	127	Shared Neighborhood Hits	24
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

USF1_HUMAN
θ value	0.0431538 (rank : 18)	NC score	0.264506 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.0431538 (rank : 19)	NC score	0.265227 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MYCN_MOUSE
θ value	0.0736092 (rank : 20)	NC score	0.241276 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	25
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

TRHY_HUMAN
θ value	0.125558 (rank : 21)	NC score	0.027468 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	1385	Shared Neighborhood Hits	25
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

MYCL1_HUMAN
θ value	0.163984 (rank : 22)	NC score	0.244848 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	146	Shared Neighborhood Hits	25
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

BMAL1_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.080428 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	22
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	0.21417 (rank : 24)	NC score	0.079485 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	121	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

HES1_HUMAN
θ value	0.21417 (rank : 25)	NC score	0.121005 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	18
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	0.21417 (rank : 26)	NC score	0.121685 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	19
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HOOK1_HUMAN
θ value	0.279714 (rank : 27)	NC score	0.035841 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	942	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

CING_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.030477 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	1432	Shared Neighborhood Hits	31
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

MYCL1_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.239953 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

BSN_MOUSE
θ value	0.813845 (rank : 30)	NC score	0.038524 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	2057	Shared Neighborhood Hits	19
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCDC6_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.044693 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	723	Shared Neighborhood Hits	25
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

NONO_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.041108 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	441	Shared Neighborhood Hits	12
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

NONO_MOUSE
θ value	0.813845 (rank : 33)	NC score	0.041023 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

HOOK1_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.031837 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	910	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

TRIPB_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.026522 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	1587	Shared Neighborhood Hits	33
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

BSN_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.043394 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	1537	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MYCS_MOUSE
θ value	1.38821 (rank : 37)	NC score	0.200490 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

SRBP1_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.111977 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	384	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP2_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.136532 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	133	Shared Neighborhood Hits	25
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

KCTD7_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.029688 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

GBP1_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.024579 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	339	Shared Neighborhood Hits	13
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

IF2M_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.028151 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	183	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

ATF6A_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.044942 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

ATF6B_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.039827 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

NEUL_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.022153 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYT8, Q9ULJ4	Gene names	NLN, KIAA1226
Domain Architecture
Description	Neurolysin, mitochondrial precursor (EC 3.4.24.16) (Neurotensin endopeptidase) (Mitochondrial oligopeptidase M) (Microsomal endopeptidase) (MEP).

KCTD7_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.022602 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MP8, Q8IVR0	Gene names	KCTD7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

SYGP1_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.018145 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

HES4_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.086891 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

MOES_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.012614 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	892	Shared Neighborhood Hits	19
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYH9_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.013395 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	1762	Shared Neighborhood Hits	32
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.013659 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	1829	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ATF6B_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.032942 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

BEGIN_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.027682 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	454	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

KTN1_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.019813 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	1197	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MINK1_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.006051 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	1477	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.006177 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	1451	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

PEPL_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.016629 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	1141	Shared Neighborhood Hits	26
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PTN12_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.006803 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

BEGIN_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.032818 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	383	Shared Neighborhood Hits	20
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BHLH2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.105045 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

M4K4_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.005010 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	1589	Shared Neighborhood Hits	21
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.005283 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	1560	Shared Neighborhood Hits	21
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

SNUT1_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.012385 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	O43290, Q53GB5	Gene names	SART1
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 1 (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (Squamous cell carcinoma antigen recognized by T cells 1) (SART-1) (hSART-1) (hSnu66).

TNIK_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.003914 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	1570	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

ZFY19_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.009346 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ARNT2_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.050407 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.050680 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	21
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.062312 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.054888 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	213	Shared Neighborhood Hits	26
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BHLH2_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.091043 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	80	Shared Neighborhood Hits	23
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH3_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.113384 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.105211 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	22
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

HES2_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.050747 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

MAX_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.224143 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	29
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.216249 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	139	Shared Neighborhood Hits	31
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MITF_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.144163 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	31
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.134485 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.054001 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.053711 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MYCB_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.112696 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

RPC5_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.065283 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

SRBP1_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.084293 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TCFL5_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.152343 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFAP4_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.060629 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

TFE3_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.154347 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	190	Shared Neighborhood Hits	36
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.105930 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.105815 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	119	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

Hits sorted by NC score

MAD4_MOUSE
NC score	0.999962 (rank : 1)	θ value	8.75112e-96 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD4_HUMAN
NC score	0.974956 (rank : 2)	θ value	1.22395e-89 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD1_MOUSE
NC score	0.919926 (rank : 3)	θ value	5.39604e-37 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_HUMAN
NC score	0.919669 (rank : 4)	θ value	3.4976e-36 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MXI1_HUMAN
NC score	0.919582 (rank : 5)	θ value	2.77131e-33 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_MOUSE
NC score	0.914988 (rank : 6)	θ value	1.12514e-34 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD3_MOUSE
NC score	0.892869 (rank : 7)	θ value	1.24688e-25 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	28
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAD3_HUMAN
NC score	0.891616 (rank : 8)	θ value	5.06226e-27 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MNT_MOUSE
NC score	0.431531 (rank : 9)	θ value	4.1701e-05 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	432	Shared Neighborhood Hits	32
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
NC score	0.413792 (rank : 10)	θ value	7.1131e-05 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	496	Shared Neighborhood Hits	33
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYC_MOUSE
NC score	0.318226 (rank : 11)	θ value	0.00228821 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	23
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
NC score	0.313785 (rank : 12)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	146	Shared Neighborhood Hits	26
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCL2_HUMAN
NC score	0.276291 (rank : 13)	θ value	0.0148317 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	17
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

USF2_HUMAN
NC score	0.275535 (rank : 14)	θ value	0.0193708 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	155	Shared Neighborhood Hits	33
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
NC score	0.275052 (rank : 15)	θ value	0.0193708 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	173	Shared Neighborhood Hits	33
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

USF1_MOUSE
NC score	0.265227 (rank : 16)	θ value	0.0431538 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.264506 (rank : 17)	θ value	0.0431538 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MYCL1_HUMAN
NC score	0.244848 (rank : 18)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	146	Shared Neighborhood Hits	25
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCN_MOUSE
NC score	0.241276 (rank : 19)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	25
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCL1_MOUSE
NC score	0.239953 (rank : 20)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCN_HUMAN
NC score	0.238531 (rank : 21)	θ value	0.0330416 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	127	Shared Neighborhood Hits	24
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MAX_HUMAN
NC score	0.224143 (rank : 22)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	29
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
NC score	0.216249 (rank : 23)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	139	Shared Neighborhood Hits	31
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MYCS_MOUSE
NC score	0.200490 (rank : 24)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

TFE3_HUMAN
NC score	0.154347 (rank : 25)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	190	Shared Neighborhood Hits	36
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TCFL5_HUMAN
NC score	0.152343 (rank : 26)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

MITF_HUMAN
NC score	0.144163 (rank : 27)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	31
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

SRBP2_HUMAN
NC score	0.136532 (rank : 28)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	133	Shared Neighborhood Hits	25
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

MITF_MOUSE
NC score	0.134485 (rank : 29)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

RPC5_HUMAN
NC score	0.125750 (rank : 30)	θ value	0.000602161 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVU0, Q9BWF7, Q9H8W8, Q9H907, Q9P276	Gene names	POLR3E, KIAA1452
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5).

HES1_MOUSE
NC score	0.121685 (rank : 31)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	19
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.121005 (rank : 32)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	18
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

BHLH3_HUMAN
NC score	0.113384 (rank : 33)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

MYCB_MOUSE
NC score	0.112696 (rank : 34)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

SRBP1_MOUSE
NC score	0.111977 (rank : 35)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	384	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TFEB_HUMAN
NC score	0.105930 (rank : 36)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
NC score	0.105815 (rank : 37)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	119	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

BHLH3_MOUSE
NC score	0.105211 (rank : 38)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	22
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BHLH2_MOUSE
NC score	0.105045 (rank : 39)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

BHLH2_HUMAN
NC score	0.091043 (rank : 40)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	80	Shared Neighborhood Hits	23
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

HES4_HUMAN
NC score	0.086891 (rank : 41)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

SRBP1_HUMAN
NC score	0.084293 (rank : 42)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

BMAL1_HUMAN
NC score	0.080428 (rank : 43)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	22
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.079485 (rank : 44)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	121	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

RPC5_MOUSE
NC score	0.065283 (rank : 45)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

ARNT_HUMAN
NC score	0.062312 (rank : 46)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

TFAP4_HUMAN
NC score	0.060629 (rank : 47)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

ARNT_MOUSE
NC score	0.054888 (rank : 48)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	213	Shared Neighborhood Hits	26
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MLX_HUMAN
NC score	0.054001 (rank : 49)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
NC score	0.053711 (rank : 50)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

HES2_MOUSE
NC score	0.050747 (rank : 51)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

ARNT2_MOUSE
NC score	0.050680 (rank : 52)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	21
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.050407 (rank : 53)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ATF6A_HUMAN
NC score	0.044942 (rank : 54)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CCDC6_HUMAN
NC score	0.044693 (rank : 55)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	723	Shared Neighborhood Hits	25
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

BSN_HUMAN
NC score	0.043394 (rank : 56)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	1537	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NONO_HUMAN
NC score	0.041108 (rank : 57)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	441	Shared Neighborhood Hits	12
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

NONO_MOUSE
NC score	0.041023 (rank : 58)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

ATF6B_HUMAN
NC score	0.039827 (rank : 59)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

BSN_MOUSE
NC score	0.038524 (rank : 60)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	2057	Shared Neighborhood Hits	19
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

HOOK1_HUMAN
NC score	0.035841 (rank : 61)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	942	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

ATF6B_MOUSE
NC score	0.032942 (rank : 62)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

BEGIN_MOUSE
NC score	0.032818 (rank : 63)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	383	Shared Neighborhood Hits	20
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

HOOK1_MOUSE
NC score	0.031837 (rank : 64)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	910	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

CING_MOUSE
NC score	0.030477 (rank : 65)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	1432	Shared Neighborhood Hits	31
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

KCTD7_MOUSE
NC score	0.029688 (rank : 66)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

IF2M_MOUSE
NC score	0.028151 (rank : 67)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	183	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

BEGIN_HUMAN
NC score	0.027682 (rank : 68)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	454	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

TRHY_HUMAN
NC score	0.027468 (rank : 69)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	1385	Shared Neighborhood Hits	25
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRIPB_HUMAN
NC score	0.026522 (rank : 70)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	1587	Shared Neighborhood Hits	33
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

GBP1_HUMAN
NC score	0.024579 (rank : 71)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	339	Shared Neighborhood Hits	13
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

KCTD7_HUMAN
NC score	0.022602 (rank : 72)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MP8, Q8IVR0	Gene names	KCTD7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

NEUL_HUMAN
NC score	0.022153 (rank : 73)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYT8, Q9ULJ4	Gene names	NLN, KIAA1226
Domain Architecture
Description	Neurolysin, mitochondrial precursor (EC 3.4.24.16) (Neurotensin endopeptidase) (Mitochondrial oligopeptidase M) (Microsomal endopeptidase) (MEP).

KTN1_HUMAN
NC score	0.019813 (rank : 74)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	1197	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

SYGP1_HUMAN
NC score	0.018145 (rank : 75)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

PEPL_HUMAN
NC score	0.016629 (rank : 76)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	1141	Shared Neighborhood Hits	26
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

MYH9_MOUSE
NC score	0.013659 (rank : 77)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	1829	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_HUMAN
NC score	0.013395 (rank : 78)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	1762	Shared Neighborhood Hits	32
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MOES_HUMAN
NC score	0.012614 (rank : 79)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	892	Shared Neighborhood Hits	19
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

SNUT1_HUMAN
NC score	0.012385 (rank : 80)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	O43290, Q53GB5	Gene names	SART1
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 1 (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (Squamous cell carcinoma antigen recognized by T cells 1) (SART-1) (hSART-1) (hSnu66).

ZFY19_HUMAN
NC score	0.009346 (rank : 81)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

PTN12_MOUSE
NC score	0.006803 (rank : 82)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

MINK1_MOUSE
NC score	0.006177 (rank : 83)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	1451	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_HUMAN
NC score	0.006051 (rank : 84)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	1477	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

M4K4_MOUSE
NC score	0.005283 (rank : 85)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	1560	Shared Neighborhood Hits	21
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.005010 (rank : 86)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	1589	Shared Neighborhood Hits	21
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

TNIK_HUMAN
NC score	0.003914 (rank : 87)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	1570	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).