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Network neighborhood for query Sequence : HES1_MOUSE

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HES1_MOUSE
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HES1_HUMAN
θ value	3.77839e-115 (rank : 1)	NC score	0.995001 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	60
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	1.81628e-109 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES4_HUMAN
θ value	1.56274e-52 (rank : 3)	NC score	0.977661 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	58	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

HES2_HUMAN
θ value	1.86321e-21 (rank : 4)	NC score	0.884414 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y543, Q96EN4, Q9Y542	Gene names	HES2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HES2_MOUSE
θ value	1.86321e-21 (rank : 5)	NC score	0.892278 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HEY2_HUMAN
θ value	5.07402e-19 (rank : 6)	NC score	0.789845 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	5.60996e-18 (rank : 7)	NC score	0.787638 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	80	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_HUMAN
θ value	6.20254e-17 (rank : 8)	NC score	0.771523 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HES6_HUMAN
θ value	1.80466e-16 (rank : 9)	NC score	0.799255 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

HEY1_MOUSE
θ value	4.02038e-16 (rank : 10)	NC score	0.774446 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HES6_MOUSE
θ value	6.85773e-16 (rank : 11)	NC score	0.789103 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHE6, Q3U2D7	Gene names	Hes6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6).

HES5_MOUSE
θ value	1.74796e-11 (rank : 12)	NC score	0.821829 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

HES7_MOUSE
θ value	2.52405e-10 (rank : 13)	NC score	0.701064 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	72	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_HUMAN
θ value	9.59137e-10 (rank : 14)	NC score	0.703848 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

BHLH3_HUMAN
θ value	4.76016e-09 (rank : 15)	NC score	0.585492 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	106	Shared Neighborhood Hits	39
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH2_HUMAN
θ value	1.06045e-08 (rank : 16)	NC score	0.580127 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	80	Shared Neighborhood Hits	38
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH3_MOUSE
θ value	1.80886e-08 (rank : 17)	NC score	0.581614 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BHLH2_MOUSE
θ value	5.26297e-08 (rank : 18)	NC score	0.563815 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

HES3_MOUSE
θ value	1.17247e-07 (rank : 19)	NC score	0.687323 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

TFE3_HUMAN
θ value	0.00298849 (rank : 20)	NC score	0.234860 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	190	Shared Neighborhood Hits	33
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_HUMAN
θ value	0.0113563 (rank : 21)	NC score	0.233812 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	113	Shared Neighborhood Hits	38
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	0.0113563 (rank : 22)	NC score	0.228803 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MAD1_MOUSE
θ value	0.0330416 (rank : 23)	NC score	0.162689 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

SRBP2_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.187460 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	133	Shared Neighborhood Hits	38
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

BMAL1_HUMAN
θ value	0.21417 (rank : 25)	NC score	0.139851 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	0.21417 (rank : 26)	NC score	0.142142 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	121	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

K1802_MOUSE
θ value	0.21417 (rank : 27)	NC score	0.024478 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	1596	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAD4_MOUSE
θ value	0.21417 (rank : 28)	NC score	0.121685 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	19
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MYOD1_HUMAN
θ value	0.21417 (rank : 29)	NC score	0.114725 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MYOD1_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.115489 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MAD4_HUMAN
θ value	0.365318 (rank : 31)	NC score	0.149368 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	94	Shared Neighborhood Hits	29
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MYOG_HUMAN
θ value	0.365318 (rank : 32)	NC score	0.112735 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
θ value	0.365318 (rank : 33)	NC score	0.111820 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

OSBL8_HUMAN
θ value	0.365318 (rank : 34)	NC score	0.032320 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

USF1_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.198169 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.365318 (rank : 36)	NC score	0.198292 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MAD1_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.140389 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

SON_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.024687 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	1568	Shared Neighborhood Hits	25
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TFEB_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.195447 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.47712 (rank : 40)	NC score	0.196051 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

RGS3_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.019618 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	1621	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NCOA1_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.070355 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA1_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.070342 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

USF2_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.183361 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	155	Shared Neighborhood Hits	31
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

ITSN1_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.005342 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	1757	Shared Neighborhood Hits	13
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MKL1_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.024537 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	667	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MYF6_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.100453 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.099925 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

SRBP1_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.171608 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

USF2_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.185868 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	173	Shared Neighborhood Hits	32
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

TRIM8_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.016505 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	650	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

NU214_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.036211 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	657	Shared Neighborhood Hits	11
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

BSN_MOUSE
θ value	2.36792 (rank : 53)	NC score	0.016642 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	2057	Shared Neighborhood Hits	26
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAC1I_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.009084 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

LSD1_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.023657 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

SRBP1_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.154735 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

HIF1A_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.033449 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

MXI1_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.120007 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.118710 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	26
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

NUMBL_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.016511 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	394	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

P2RX2_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.013615 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

RB6I2_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.005626 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	1433	Shared Neighborhood Hits	13
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

TMEPA_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.031277 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

TRIM8_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.013555 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	674	Shared Neighborhood Hits	5
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

MAGE1_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.010833 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	1389	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAP1A_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.013759 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	1626	Shared Neighborhood Hits	22
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RAI1_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.019301 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SOX30_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.010324 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	374	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

G3ST4_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.011583 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RP7, Q8N3P7, Q8WZ17, Q96E33, Q9HA78	Gene names	GAL3ST4
Domain Architecture
Description	Galactose-3-O-sulfotransferase 4 (EC 2.8.2.-) (Galbeta1-3GalNAc 3'- sulfotransferase) (Beta-galactose-3-O-sulfotransferase 4).

IRK3_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.003961 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	P48549, Q8TBI0	Gene names	KCNJ3, GIRK1
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

MYF5_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.073288 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF5_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.072509 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

NFH_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.003133 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	2247	Shared Neighborhood Hits	21
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CHD5_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.002297 (rank : 90)
Query Neighborhood Hits	78	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

HIF1A_MOUSE
θ value	8.99809 (rank : 75)	NC score	0.028742 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

MYO15_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.006089 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	671	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

ZN142_HUMAN
θ value	8.99809 (rank : 77)	NC score	-0.002359 (rank : 91)
Query Neighborhood Hits	78	Target Neighborhood Hits	1007	Shared Neighborhood Hits	9
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

ZN692_HUMAN
θ value	8.99809 (rank : 78)	NC score	-0.002370 (rank : 92)
Query Neighborhood Hits	78	Target Neighborhood Hits	808	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

ARNT2_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.073803 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.075318 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	115	Shared Neighborhood Hits	30
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.076331 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.076143 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

CLOCK_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.062299 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	127	Shared Neighborhood Hits	27
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.060693 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

MAD3_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.093715 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	92	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.081705 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAX_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.072146 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.073005 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MLX_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.126264 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.129535 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	26
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MNT_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.053801 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	496	Shared Neighborhood Hits	41
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.057071 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	432	Shared Neighborhood Hits	40
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

Hits sorted by NC score

HES1_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.81628e-109 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.995001 (rank : 2)	θ value	3.77839e-115 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	60
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES4_HUMAN
NC score	0.977661 (rank : 3)	θ value	1.56274e-52 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	58	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

HES2_MOUSE
NC score	0.892278 (rank : 4)	θ value	1.86321e-21 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HES2_HUMAN
NC score	0.884414 (rank : 5)	θ value	1.86321e-21 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y543, Q96EN4, Q9Y542	Gene names	HES2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

HES5_MOUSE
NC score	0.821829 (rank : 6)	θ value	1.74796e-11 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

HES6_HUMAN
NC score	0.799255 (rank : 7)	θ value	1.80466e-16 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

HEY2_HUMAN
NC score	0.789845 (rank : 8)	θ value	5.07402e-19 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HES6_MOUSE
NC score	0.789103 (rank : 9)	θ value	6.85773e-16 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHE6, Q3U2D7	Gene names	Hes6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6).

HEY2_MOUSE
NC score	0.787638 (rank : 10)	θ value	5.60996e-18 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	80	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_MOUSE
NC score	0.774446 (rank : 11)	θ value	4.02038e-16 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY1_HUMAN
NC score	0.771523 (rank : 12)	θ value	6.20254e-17 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HES7_HUMAN
NC score	0.703848 (rank : 13)	θ value	9.59137e-10 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_MOUSE
NC score	0.701064 (rank : 14)	θ value	2.52405e-10 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	72	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES3_MOUSE
NC score	0.687323 (rank : 15)	θ value	1.17247e-07 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

BHLH3_HUMAN
NC score	0.585492 (rank : 16)	θ value	4.76016e-09 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	106	Shared Neighborhood Hits	39
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
NC score	0.581614 (rank : 17)	θ value	1.80886e-08 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BHLH2_HUMAN
NC score	0.580127 (rank : 18)	θ value	1.06045e-08 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	80	Shared Neighborhood Hits	38
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
NC score	0.563815 (rank : 19)	θ value	5.26297e-08 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

TFE3_HUMAN
NC score	0.234860 (rank : 20)	θ value	0.00298849 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	190	Shared Neighborhood Hits	33
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_HUMAN
NC score	0.233812 (rank : 21)	θ value	0.0113563 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	113	Shared Neighborhood Hits	38
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.228803 (rank : 22)	θ value	0.0113563 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

USF1_MOUSE
NC score	0.198292 (rank : 23)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.198169 (rank : 24)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

TFEB_MOUSE
NC score	0.196051 (rank : 25)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.195447 (rank : 26)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	111	Shared Neighborhood Hits	32
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

SRBP2_HUMAN
NC score	0.187460 (rank : 27)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	133	Shared Neighborhood Hits	38
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

USF2_MOUSE
NC score	0.185868 (rank : 28)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	173	Shared Neighborhood Hits	32
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

USF2_HUMAN
NC score	0.183361 (rank : 29)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	155	Shared Neighborhood Hits	31
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

SRBP1_HUMAN
NC score	0.171608 (rank : 30)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MAD1_MOUSE
NC score	0.162689 (rank : 31)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

SRBP1_MOUSE
NC score	0.154735 (rank : 32)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MAD4_HUMAN
NC score	0.149368 (rank : 33)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	94	Shared Neighborhood Hits	29
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

BMAL1_MOUSE
NC score	0.142142 (rank : 34)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	121	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

MAD1_HUMAN
NC score	0.140389 (rank : 35)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

BMAL1_HUMAN
NC score	0.139851 (rank : 36)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

MLX_MOUSE
NC score	0.129535 (rank : 37)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	26
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.126264 (rank : 38)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MAD4_MOUSE
NC score	0.121685 (rank : 39)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	19
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MXI1_HUMAN
NC score	0.120007 (rank : 40)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_MOUSE
NC score	0.118710 (rank : 41)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	26
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MYOD1_MOUSE
NC score	0.115489 (rank : 42)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MYOD1_HUMAN
NC score	0.114725 (rank : 43)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	14
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MYOG_HUMAN
NC score	0.112735 (rank : 44)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
NC score	0.111820 (rank : 45)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

MYF6_HUMAN
NC score	0.100453 (rank : 46)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
NC score	0.099925 (rank : 47)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

MAD3_HUMAN
NC score	0.093715 (rank : 48)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	92	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
NC score	0.081705 (rank : 49)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

ARNT_HUMAN
NC score	0.076331 (rank : 50)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
NC score	0.076143 (rank : 51)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT2_MOUSE
NC score	0.075318 (rank : 52)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	115	Shared Neighborhood Hits	30
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.073803 (rank : 53)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

MYF5_HUMAN
NC score	0.073288 (rank : 54)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MAX_MOUSE
NC score	0.073005 (rank : 55)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MYF5_MOUSE
NC score	0.072509 (rank : 56)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MAX_HUMAN
NC score	0.072146 (rank : 57)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

NCOA1_HUMAN
NC score	0.070355 (rank : 58)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA1_MOUSE
NC score	0.070342 (rank : 59)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

CLOCK_HUMAN
NC score	0.062299 (rank : 60)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	127	Shared Neighborhood Hits	27
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
NC score	0.060693 (rank : 61)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

MNT_MOUSE
NC score	0.057071 (rank : 62)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	78	Target Neighborhood Hits	432	Shared Neighborhood Hits	40
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
NC score	0.053801 (rank : 63)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	78	Target Neighborhood Hits	496	Shared Neighborhood Hits	41
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NU214_HUMAN
NC score	0.036211 (rank : 64)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	657	Shared Neighborhood Hits	11
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

HIF1A_HUMAN
NC score	0.033449 (rank : 65)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

OSBL8_HUMAN
NC score	0.032320 (rank : 66)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

TMEPA_MOUSE
NC score	0.031277 (rank : 67)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7R2, Q9EQH9	Gene names	Tmepai, N4wbp4
Domain Architecture	No domain graphic available
Description	Transmembrane prostate androgen-induced protein (NEDD4 WW domain- binding protein 4).

HIF1A_MOUSE
NC score	0.028742 (rank : 68)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

SON_HUMAN
NC score	0.024687 (rank : 69)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	1568	Shared Neighborhood Hits	25
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MKL1_MOUSE
NC score	0.024537 (rank : 70)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	667	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

K1802_MOUSE
NC score	0.024478 (rank : 71)	θ value	0.21417 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	1596	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LSD1_HUMAN
NC score	0.023657 (rank : 72)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

RGS3_MOUSE
NC score	0.019618 (rank : 73)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	1621	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RAI1_MOUSE
NC score	0.019301 (rank : 74)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

BSN_MOUSE
NC score	0.016642 (rank : 75)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	2057	Shared Neighborhood Hits	26
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NUMBL_HUMAN
NC score	0.016511 (rank : 76)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	394	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

TRIM8_HUMAN
NC score	0.016505 (rank : 77)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	650	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

MAP1A_HUMAN
NC score	0.013759 (rank : 78)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	1626	Shared Neighborhood Hits	22
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

P2RX2_HUMAN
NC score	0.013615 (rank : 79)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

TRIM8_MOUSE
NC score	0.013555 (rank : 80)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	674	Shared Neighborhood Hits	5
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

G3ST4_HUMAN
NC score	0.011583 (rank : 81)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RP7, Q8N3P7, Q8WZ17, Q96E33, Q9HA78	Gene names	GAL3ST4
Domain Architecture
Description	Galactose-3-O-sulfotransferase 4 (EC 2.8.2.-) (Galbeta1-3GalNAc 3'- sulfotransferase) (Beta-galactose-3-O-sulfotransferase 4).

MAGE1_HUMAN
NC score	0.010833 (rank : 82)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	1389	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SOX30_MOUSE
NC score	0.010324 (rank : 83)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	374	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

CAC1I_HUMAN
NC score	0.009084 (rank : 84)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

MYO15_HUMAN
NC score	0.006089 (rank : 85)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	671	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RB6I2_MOUSE
NC score	0.005626 (rank : 86)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	1433	Shared Neighborhood Hits	13
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

ITSN1_HUMAN
NC score	0.005342 (rank : 87)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	1757	Shared Neighborhood Hits	13
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

IRK3_HUMAN
NC score	0.003961 (rank : 88)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	P48549, Q8TBI0	Gene names	KCNJ3, GIRK1
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

NFH_MOUSE
NC score	0.003133 (rank : 89)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	2247	Shared Neighborhood Hits	21
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CHD5_HUMAN
NC score	0.002297 (rank : 90)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

ZN142_HUMAN
NC score	-0.002359 (rank : 91)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	1007	Shared Neighborhood Hits	9
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

ZN692_HUMAN
NC score	-0.002370 (rank : 92)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	808	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.