Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : MXI1_MOUSE

For an explanation of this page, click here

MXI1_MOUSE
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MXI1_MOUSE
θ value	3.21347e-98 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
θ value	1.65039e-94 (rank : 2)	NC score	0.994807 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	74
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD1_HUMAN
θ value	1.19932e-44 (rank : 3)	NC score	0.924945 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_MOUSE
θ value	4.71619e-41 (rank : 4)	NC score	0.923602 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	75	Shared Neighborhood Hits	37
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD4_HUMAN
θ value	1.05066e-40 (rank : 5)	NC score	0.920874 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	45
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD4_MOUSE
θ value	1.12514e-34 (rank : 6)	NC score	0.914988 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD3_HUMAN
θ value	2.35151e-24 (rank : 7)	NC score	0.897169 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	3.07116e-24 (rank : 8)	NC score	0.898064 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MNT_MOUSE
θ value	5.08577e-11 (rank : 9)	NC score	0.520747 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	432	Shared Neighborhood Hits	45
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
θ value	1.133e-10 (rank : 10)	NC score	0.500941 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	496	Shared Neighborhood Hits	47
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYC_MOUSE
θ value	1.69304e-06 (rank : 11)	NC score	0.394275 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
θ value	6.43352e-06 (rank : 12)	NC score	0.390235 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	146	Shared Neighborhood Hits	40
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCL1_MOUSE
θ value	0.00035302 (rank : 13)	NC score	0.327287 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

USF1_HUMAN
θ value	0.00035302 (rank : 14)	NC score	0.343946 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.00035302 (rank : 15)	NC score	0.345041 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MYCL1_HUMAN
θ value	0.000461057 (rank : 16)	NC score	0.328885 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	146	Shared Neighborhood Hits	36
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
θ value	0.000786445 (rank : 17)	NC score	0.343227 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

USF2_HUMAN
θ value	0.00102713 (rank : 18)	NC score	0.347672 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	155	Shared Neighborhood Hits	44
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.00102713 (rank : 19)	NC score	0.345977 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	173	Shared Neighborhood Hits	44
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

TFE3_HUMAN
θ value	0.0193708 (rank : 20)	NC score	0.257254 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

BHLH3_HUMAN
θ value	0.0252991 (rank : 21)	NC score	0.193074 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	106	Shared Neighborhood Hits	29
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
θ value	0.0330416 (rank : 22)	NC score	0.185644 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

MYCN_HUMAN
θ value	0.0330416 (rank : 23)	NC score	0.300630 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

CIR_HUMAN
θ value	0.0431538 (rank : 24)	NC score	0.080371 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	249	Shared Neighborhood Hits	10
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

MYCN_MOUSE
θ value	0.0431538 (rank : 25)	NC score	0.304409 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	40
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MAX_HUMAN
θ value	0.0563607 (rank : 26)	NC score	0.343957 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	39
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MITF_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.243347 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TCFL5_HUMAN
θ value	0.0736092 (rank : 28)	NC score	0.223373 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

MAX_MOUSE
θ value	0.125558 (rank : 29)	NC score	0.334517 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	139	Shared Neighborhood Hits	44
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MITF_MOUSE
θ value	0.125558 (rank : 30)	NC score	0.233535 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	43
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

DESP_HUMAN
θ value	0.279714 (rank : 31)	NC score	0.039307 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	1470	Shared Neighborhood Hits	56
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

SRBP2_HUMAN
θ value	0.365318 (rank : 32)	NC score	0.179617 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	133	Shared Neighborhood Hits	37
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

AZI1_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.046158 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	990	Shared Neighborhood Hits	49
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BHLH2_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.151189 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	30
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

CCDC9_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.047432 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

BSN_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.049663 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	1537	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MYCS_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.251052 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

TFEB_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.201654 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	111	Shared Neighborhood Hits	38
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.203287 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

BHLH2_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.162617 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

KI21A_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.024631 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	1317	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MYH10_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.030342 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	1620	Shared Neighborhood Hits	58
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RSRC1_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.044042 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	11
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

GOGA3_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.037285 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	1437	Shared Neighborhood Hits	52
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

HAP1_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.044248 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	388	Shared Neighborhood Hits	27
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

HOOK2_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.041802 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	714	Shared Neighborhood Hits	47
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

BSN_MOUSE
θ value	1.81305 (rank : 47)	NC score	0.041494 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	2057	Shared Neighborhood Hits	39
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KI21A_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.025198 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	1543	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

SDCG8_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.038614 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	886	Shared Neighborhood Hits	49
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

CT116_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.051463 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	294	Shared Neighborhood Hits	27
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

M4K4_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.011123 (rank : 121)
Query Neighborhood Hits	109	Target Neighborhood Hits	1589	Shared Neighborhood Hits	44
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.010688 (rank : 124)
Query Neighborhood Hits	109	Target Neighborhood Hits	1560	Shared Neighborhood Hits	43
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MYH11_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.029132 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	1806	Shared Neighborhood Hits	58
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYO7A_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.018590 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	209	Shared Neighborhood Hits	13
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

SUHW1_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.005844 (rank : 125)
Query Neighborhood Hits	109	Target Neighborhood Hits	648	Shared Neighborhood Hits	3
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

HES1_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.118173 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.118710 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HOOK2_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.036300 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	736	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

NDF2_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.038935 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.038920 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	111	Shared Neighborhood Hits	12
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

UACA_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.024485 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	1622	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ANK2_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.004956 (rank : 126)
Query Neighborhood Hits	109	Target Neighborhood Hits	1615	Shared Neighborhood Hits	24
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BBX_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.017399 (rank : 115)
Query Neighborhood Hits	109	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

CCDC9_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.038207 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CT116_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.041515 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

GOGA3_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.037384 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	1317	Shared Neighborhood Hits	51
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

K1967_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.022745 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

MINK1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.010884 (rank : 122)
Query Neighborhood Hits	109	Target Neighborhood Hits	1477	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.010797 (rank : 123)
Query Neighborhood Hits	109	Target Neighborhood Hits	1451	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

NDF1_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.032996 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	209	Shared Neighborhood Hits	13
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NIN_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.030966 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	1416	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RB6I2_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.034166 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	1584	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.035726 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	1433	Shared Neighborhood Hits	59
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

SRBP1_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.142961 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	384	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

AFAD_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.019312 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	689	Shared Neighborhood Hits	30
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AMOL1_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.024103 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	435	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

ARNT_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.068698 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ASCL2_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.060362 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	98	Shared Neighborhood Hits	17
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

CCD13_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.033483 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	721	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CD2L5_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.002880 (rank : 128)
Query Neighborhood Hits	109	Target Neighborhood Hits	987	Shared Neighborhood Hits	9
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

CD2L5_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.002887 (rank : 127)
Query Neighborhood Hits	109	Target Neighborhood Hits	1011	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CV106_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.022414 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

EEA1_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.030366 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	1637	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MYH11_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.027900 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	1777	Shared Neighborhood Hits	56
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NDF1_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.031431 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	186	Shared Neighborhood Hits	13
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

RBM25_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.025173 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	682	Shared Neighborhood Hits	33
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SRBP1_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.130709 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	38
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TAB2_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.020292 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	245	Shared Neighborhood Hits	15
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

TPR_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.028193 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	1921	Shared Neighborhood Hits	53
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

VIME_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.014637 (rank : 118)
Query Neighborhood Hits	109	Target Neighborhood Hits	716	Shared Neighborhood Hits	39
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

AZI1_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.043245 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	1000	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

HIP1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.034794 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	1016	Shared Neighborhood Hits	53
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

IF3A_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.029364 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	875	Shared Neighborhood Hits	47
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

MKL2_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.019819 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

MYH10_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.028970 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	1612	Shared Neighborhood Hits	60
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

STIM1_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.026931 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	660	Shared Neighborhood Hits	42
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SYNE2_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.021189 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	1323	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TRIPB_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.036212 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	1587	Shared Neighborhood Hits	62
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ATX7_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.025865 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

EEA1_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.029474 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	1796	Shared Neighborhood Hits	56
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GOGA2_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.027915 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	944	Shared Neighborhood Hits	48
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

IF3A_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.027441 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	871	Shared Neighborhood Hits	43
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

ITSN2_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.017082 (rank : 117)
Query Neighborhood Hits	109	Target Neighborhood Hits	1173	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.018870 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	1371	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

K1688_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.013248 (rank : 120)
Query Neighborhood Hits	109	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

KNTC2_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.026432 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	692	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

MYO7A_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.017613 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

SAFB2_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.017338 (rank : 116)
Query Neighborhood Hits	109	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

VIME_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.013734 (rank : 119)
Query Neighborhood Hits	109	Target Neighborhood Hits	706	Shared Neighborhood Hits	38
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

ARNT2_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.050549 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.050982 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.059132 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	213	Shared Neighborhood Hits	35
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BHLH8_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.062154 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	123	Shared Neighborhood Hits	23
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.069759 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BMAL1_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.065265 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	32
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.064310 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

FIGLA_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.061131 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

FIGLA_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.055403 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	17
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

HES4_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.086741 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

HEY1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.050739 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.052897 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.056554 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.056952 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MLX_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.088264 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.091477 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MYCB_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.152237 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

TFAP4_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.109135 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	289	Shared Neighborhood Hits	46
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

WBS14_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.064939 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	273	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

Hits sorted by NC score

MXI1_MOUSE
NC score	0.999962 (rank : 1)	θ value	3.21347e-98 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
NC score	0.994807 (rank : 2)	θ value	1.65039e-94 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	74
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD1_HUMAN
NC score	0.924945 (rank : 3)	θ value	1.19932e-44 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_MOUSE
NC score	0.923602 (rank : 4)	θ value	4.71619e-41 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	75	Shared Neighborhood Hits	37
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD4_HUMAN
NC score	0.920874 (rank : 5)	θ value	1.05066e-40 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	45
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD4_MOUSE
NC score	0.914988 (rank : 6)	θ value	1.12514e-34 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD3_MOUSE
NC score	0.898064 (rank : 7)	θ value	3.07116e-24 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAD3_HUMAN
NC score	0.897169 (rank : 8)	θ value	2.35151e-24 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MNT_MOUSE
NC score	0.520747 (rank : 9)	θ value	5.08577e-11 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	432	Shared Neighborhood Hits	45
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
NC score	0.500941 (rank : 10)	θ value	1.133e-10 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	496	Shared Neighborhood Hits	47
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYC_MOUSE
NC score	0.394275 (rank : 11)	θ value	1.69304e-06 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
NC score	0.390235 (rank : 12)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	146	Shared Neighborhood Hits	40
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

USF2_HUMAN
NC score	0.347672 (rank : 13)	θ value	0.00102713 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	155	Shared Neighborhood Hits	44
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
NC score	0.345977 (rank : 14)	θ value	0.00102713 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	173	Shared Neighborhood Hits	44
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

USF1_MOUSE
NC score	0.345041 (rank : 15)	θ value	0.00035302 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MAX_HUMAN
NC score	0.343957 (rank : 16)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	39
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

USF1_HUMAN
NC score	0.343946 (rank : 17)	θ value	0.00035302 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MYCL2_HUMAN
NC score	0.343227 (rank : 18)	θ value	0.000786445 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MAX_MOUSE
NC score	0.334517 (rank : 19)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	139	Shared Neighborhood Hits	44
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MYCL1_HUMAN
NC score	0.328885 (rank : 20)	θ value	0.000461057 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	146	Shared Neighborhood Hits	36
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
NC score	0.327287 (rank : 21)	θ value	0.00035302 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCN_MOUSE
NC score	0.304409 (rank : 22)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	40
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.300630 (rank : 23)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

TFE3_HUMAN
NC score	0.257254 (rank : 24)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MYCS_MOUSE
NC score	0.251052 (rank : 25)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MITF_HUMAN
NC score	0.243347 (rank : 26)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.233535 (rank : 27)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	43
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TCFL5_HUMAN
NC score	0.223373 (rank : 28)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFEB_MOUSE
NC score	0.203287 (rank : 29)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.201654 (rank : 30)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	111	Shared Neighborhood Hits	38
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

BHLH3_HUMAN
NC score	0.193074 (rank : 31)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	106	Shared Neighborhood Hits	29
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
NC score	0.185644 (rank : 32)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

SRBP2_HUMAN
NC score	0.179617 (rank : 33)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	133	Shared Neighborhood Hits	37
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

BHLH2_MOUSE
NC score	0.162617 (rank : 34)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

MYCB_MOUSE
NC score	0.152237 (rank : 35)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	109	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

BHLH2_HUMAN
NC score	0.151189 (rank : 36)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	30
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

SRBP1_MOUSE
NC score	0.142961 (rank : 37)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	384	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_HUMAN
NC score	0.130709 (rank : 38)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	38
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

HES1_MOUSE
NC score	0.118710 (rank : 39)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.118173 (rank : 40)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

TFAP4_HUMAN
NC score	0.109135 (rank : 41)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	109	Target Neighborhood Hits	289	Shared Neighborhood Hits	46
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

MLX_MOUSE
NC score	0.091477 (rank : 42)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.088264 (rank : 43)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	109	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

HES4_HUMAN
NC score	0.086741 (rank : 44)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	109	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

CIR_HUMAN
NC score	0.080371 (rank : 45)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	249	Shared Neighborhood Hits	10
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

BHLH8_MOUSE
NC score	0.069759 (rank : 46)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

ARNT_HUMAN
NC score	0.068698 (rank : 47)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BMAL1_HUMAN
NC score	0.065265 (rank : 48)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	32
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

WBS14_HUMAN
NC score	0.064939 (rank : 49)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	109	Target Neighborhood Hits	273	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

BMAL1_MOUSE
NC score	0.064310 (rank : 50)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	109	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

BHLH8_HUMAN
NC score	0.062154 (rank : 51)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	123	Shared Neighborhood Hits	23
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

FIGLA_HUMAN
NC score	0.061131 (rank : 52)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

ASCL2_MOUSE
NC score	0.060362 (rank : 53)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	98	Shared Neighborhood Hits	17
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

ARNT_MOUSE
NC score	0.059132 (rank : 54)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	213	Shared Neighborhood Hits	35
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

HEY2_MOUSE
NC score	0.056952 (rank : 55)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY2_HUMAN
NC score	0.056554 (rank : 56)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

FIGLA_MOUSE
NC score	0.055403 (rank : 57)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	17
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

HEY1_MOUSE
NC score	0.052897 (rank : 58)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

CT116_HUMAN
NC score	0.051463 (rank : 59)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	294	Shared Neighborhood Hits	27
SwissProt Accessions	Q96HY6, Q9BW47	Gene names	C20orf116
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 precursor.

ARNT2_MOUSE
NC score	0.050982 (rank : 60)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

HEY1_HUMAN
NC score	0.050739 (rank : 61)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	109	Target Neighborhood Hits	82	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

ARNT2_HUMAN
NC score	0.050549 (rank : 62)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

BSN_HUMAN
NC score	0.049663 (rank : 63)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	1537	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CCDC9_HUMAN
NC score	0.047432 (rank : 64)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

AZI1_MOUSE
NC score	0.046158 (rank : 65)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	990	Shared Neighborhood Hits	49
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

HAP1_MOUSE
NC score	0.044248 (rank : 66)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	388	Shared Neighborhood Hits	27
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

RSRC1_HUMAN
NC score	0.044042 (rank : 67)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	11
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

AZI1_HUMAN
NC score	0.043245 (rank : 68)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	1000	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

HOOK2_HUMAN
NC score	0.041802 (rank : 69)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	714	Shared Neighborhood Hits	47
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

CT116_MOUSE
NC score	0.041515 (rank : 70)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

BSN_MOUSE
NC score	0.041494 (rank : 71)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	2057	Shared Neighborhood Hits	39
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DESP_HUMAN
NC score	0.039307 (rank : 72)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	1470	Shared Neighborhood Hits	56
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

NDF2_HUMAN
NC score	0.038935 (rank : 73)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
NC score	0.038920 (rank : 74)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	111	Shared Neighborhood Hits	12
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

SDCG8_MOUSE
NC score	0.038614 (rank : 75)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	886	Shared Neighborhood Hits	49
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

CCDC9_MOUSE
NC score	0.038207 (rank : 76)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

GOGA3_HUMAN
NC score	0.037384 (rank : 77)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	1317	Shared Neighborhood Hits	51
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
NC score	0.037285 (rank : 78)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	1437	Shared Neighborhood Hits	52
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

HOOK2_MOUSE
NC score	0.036300 (rank : 79)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	736	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

TRIPB_HUMAN
NC score	0.036212 (rank : 80)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	1587	Shared Neighborhood Hits	62
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

RB6I2_MOUSE
NC score	0.035726 (rank : 81)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	1433	Shared Neighborhood Hits	59
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

HIP1_HUMAN
NC score	0.034794 (rank : 82)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	1016	Shared Neighborhood Hits	53
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

RB6I2_HUMAN
NC score	0.034166 (rank : 83)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	1584	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CCD13_HUMAN
NC score	0.033483 (rank : 84)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	721	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

NDF1_MOUSE
NC score	0.032996 (rank : 85)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	209	Shared Neighborhood Hits	13
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF1_HUMAN
NC score	0.031431 (rank : 86)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	186	Shared Neighborhood Hits	13
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NIN_HUMAN
NC score	0.030966 (rank : 87)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	1416	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

EEA1_MOUSE
NC score	0.030366 (rank : 88)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	1637	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MYH10_HUMAN
NC score	0.030342 (rank : 89)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	1620	Shared Neighborhood Hits	58
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

EEA1_HUMAN
NC score	0.029474 (rank : 90)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	1796	Shared Neighborhood Hits	56
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

IF3A_HUMAN
NC score	0.029364 (rank : 91)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	875	Shared Neighborhood Hits	47
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

MYH11_HUMAN
NC score	0.029132 (rank : 92)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	1806	Shared Neighborhood Hits	58
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH10_MOUSE
NC score	0.028970 (rank : 93)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	1612	Shared Neighborhood Hits	60
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

TPR_HUMAN
NC score	0.028193 (rank : 94)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	1921	Shared Neighborhood Hits	53
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

GOGA2_MOUSE
NC score	0.027915 (rank : 95)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	944	Shared Neighborhood Hits	48
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

MYH11_MOUSE
NC score	0.027900 (rank : 96)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	1777	Shared Neighborhood Hits	56
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

IF3A_MOUSE
NC score	0.027441 (rank : 97)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	871	Shared Neighborhood Hits	43
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

STIM1_MOUSE
NC score	0.026931 (rank : 98)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	660	Shared Neighborhood Hits	42
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

KNTC2_MOUSE
NC score	0.026432 (rank : 99)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	692	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

ATX7_HUMAN
NC score	0.025865 (rank : 100)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

KI21A_HUMAN
NC score	0.025198 (rank : 101)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	1543	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

RBM25_HUMAN
NC score	0.025173 (rank : 102)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	682	Shared Neighborhood Hits	33
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

KI21A_MOUSE
NC score	0.024631 (rank : 103)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	1317	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

UACA_HUMAN
NC score	0.024485 (rank : 104)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	1622	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AMOL1_HUMAN
NC score	0.024103 (rank : 105)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	435	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

K1967_MOUSE
NC score	0.022745 (rank : 106)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

CV106_HUMAN
NC score	0.022414 (rank : 107)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

SYNE2_HUMAN
NC score	0.021189 (rank : 108)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	1323	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TAB2_MOUSE
NC score	0.020292 (rank : 109)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	245	Shared Neighborhood Hits	15
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

MKL2_MOUSE
NC score	0.019819 (rank : 110)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

AFAD_HUMAN
NC score	0.019312 (rank : 111)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	689	Shared Neighborhood Hits	30
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ITSN2_MOUSE
NC score	0.018870 (rank : 112)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	1371	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MYO7A_HUMAN
NC score	0.018590 (rank : 113)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	209	Shared Neighborhood Hits	13
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
NC score	0.017613 (rank : 114)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

BBX_HUMAN
NC score	0.017399 (rank : 115)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

SAFB2_MOUSE
NC score	0.017338 (rank : 116)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

ITSN2_HUMAN
NC score	0.017082 (rank : 117)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	1173	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

VIME_MOUSE
NC score	0.014637 (rank : 118)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	716	Shared Neighborhood Hits	39
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

VIME_HUMAN
NC score	0.013734 (rank : 119)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	706	Shared Neighborhood Hits	38
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

K1688_HUMAN
NC score	0.013248 (rank : 120)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

M4K4_HUMAN
NC score	0.011123 (rank : 121)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	1589	Shared Neighborhood Hits	44
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MINK1_HUMAN
NC score	0.010884 (rank : 122)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	1477	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
NC score	0.010797 (rank : 123)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	1451	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

M4K4_MOUSE
NC score	0.010688 (rank : 124)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	1560	Shared Neighborhood Hits	43
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

SUHW1_HUMAN
NC score	0.005844 (rank : 125)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	648	Shared Neighborhood Hits	3
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

ANK2_HUMAN
NC score	0.004956 (rank : 126)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	1615	Shared Neighborhood Hits	24
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CD2L5_MOUSE
NC score	0.002887 (rank : 127)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	1011	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CD2L5_HUMAN
NC score	0.002880 (rank : 128)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	987	Shared Neighborhood Hits	9
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).