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Network neighborhood for query Sequence : MLX_MOUSE

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MLX_MOUSE
 
SwissProt Accessions O08609, Q9EQJ7, Q9EQJ8 Gene names Mlx, Tcfl4
Domain
Architecture
Description Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).
Rank Plots



Hits sorted by θ


MLX_MOUSE
 
θ value 9.19922e-154 (rank : 1) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 100 Target Neighborhood Hits 100 Shared Neighborhood Hits 100
SwissProt Accessions O08609, Q9EQJ7, Q9EQJ8 Gene names Mlx, Tcfl4
Domain
Architecture
Description Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).
MLX_HUMAN
 
θ value 2.42647e-146 (rank : 2) NC score 0.995677 (rank : 2)
Query Neighborhood Hits 100 Target Neighborhood Hits 95 Shared Neighborhood Hits 92
SwissProt Accessions Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3 Gene names MLX, TCFL4
Domain
Architecture
Description Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).
WBS14_MOUSE
 
θ value 5.07402e-19 (rank : 3) NC score 0.558132 (rank : 3)
Query Neighborhood Hits 100 Target Neighborhood Hits 171 Shared Neighborhood Hits 16
SwissProt Accessions Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5 Gene names Mlxipl, Mio, Wbscr14
Domain
Architecture
Description Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).
WBS14_HUMAN
 
θ value 4.29542e-18 (rank : 4) NC score 0.526280 (rank : 4)
Query Neighborhood Hits 100 Target Neighborhood Hits 273 Shared Neighborhood Hits 22
SwissProt Accessions Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3 Gene names MLXIPL, MIO, WBSCR14
Domain
Architecture
Description Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).
HEY1_HUMAN
 
θ value 2.21117e-06 (rank : 5) NC score 0.360723 (rank : 11)
Query Neighborhood Hits 100 Target Neighborhood Hits 82 Shared Neighborhood Hits 38
SwissProt Accessions Q9Y5J3, Q5TZS3, Q9NYP4 Gene names HEY1, CHF2, HESR1
Domain
Architecture
Description Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).
MAX_MOUSE
 
θ value 3.77169e-06 (rank : 6) NC score 0.471341 (rank : 5)
Query Neighborhood Hits 100 Target Neighborhood Hits 139 Shared Neighborhood Hits 46
SwissProt Accessions P28574 Gene names Max, Myn
Domain
Architecture
Description Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).
USF1_HUMAN
 
θ value 6.43352e-06 (rank : 7) NC score 0.432230 (rank : 8)
Query Neighborhood Hits 100 Target Neighborhood Hits 70 Shared Neighborhood Hits 41
SwissProt Accessions P22415 Gene names USF1, USF
Domain
Architecture
Description Upstream stimulatory factor 1 (Major late transcription factor 1).
USF1_MOUSE
 
θ value 6.43352e-06 (rank : 8) NC score 0.432604 (rank : 7)
Query Neighborhood Hits 100 Target Neighborhood Hits 71 Shared Neighborhood Hits 41
SwissProt Accessions Q61069 Gene names Usf1, Usf
Domain
Architecture
Description Upstream stimulatory factor 1 (Major late transcription factor 1).
HEY1_MOUSE
 
θ value 8.40245e-06 (rank : 9) NC score 0.358160 (rank : 12)
Query Neighborhood Hits 100 Target Neighborhood Hits 69 Shared Neighborhood Hits 38
SwissProt Accessions Q9WV93 Gene names Hey1, Hesr1
Domain
Architecture
Description Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).
MAX_HUMAN
 
θ value 1.43324e-05 (rank : 10) NC score 0.461639 (rank : 6)
Query Neighborhood Hits 100 Target Neighborhood Hits 125 Shared Neighborhood Hits 45
SwissProt Accessions P61244, P25912, P52163 Gene names MAX
Domain
Architecture
Description Protein max (Myc-associated factor X).
TFAP4_HUMAN
 
θ value 9.29e-05 (rank : 11) NC score 0.351072 (rank : 13)
Query Neighborhood Hits 100 Target Neighborhood Hits 289 Shared Neighborhood Hits 44
SwissProt Accessions Q01664, O60409 Gene names TFAP4
Domain
Architecture
Description Transcription factor AP-4 (Activating enhancer-binding protein 4).
USF2_HUMAN
 
θ value 0.000121331 (rank : 12) NC score 0.421414 (rank : 10)
Query Neighborhood Hits 100 Target Neighborhood Hits 155 Shared Neighborhood Hits 47
SwissProt Accessions Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852 Gene names USF2
Domain
Architecture
Description Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).
USF2_MOUSE
 
θ value 0.000121331 (rank : 13) NC score 0.425036 (rank : 9)
Query Neighborhood Hits 100 Target Neighborhood Hits 173 Shared Neighborhood Hits 47
SwissProt Accessions Q64705, Q3UIL2, Q8VE59 Gene names Usf2
Domain
Architecture
Description Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).
BMAL1_HUMAN
 
θ value 0.000461057 (rank : 14) NC score 0.224782 (rank : 30)
Query Neighborhood Hits 100 Target Neighborhood Hits 115 Shared Neighborhood Hits 43
SwissProt Accessions O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649 Gene names ARNTL, BMAL1, MOP3
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).
SRBP1_MOUSE
 
θ value 0.000461057 (rank : 15) NC score 0.284117 (rank : 21)
Query Neighborhood Hits 100 Target Neighborhood Hits 384 Shared Neighborhood Hits 50
SwissProt Accessions Q9WTN3 Gene names Srebf1, Srebp1
Domain
Architecture
Description Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).
SRBP1_HUMAN
 
θ value 0.000786445 (rank : 16) NC score 0.289732 (rank : 18)
Query Neighborhood Hits 100 Target Neighborhood Hits 225 Shared Neighborhood Hits 46
SwissProt Accessions P36956, Q16062 Gene names SREBF1, SREBP1
Domain
Architecture
Description Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).
BMAL1_MOUSE
 
θ value 0.00102713 (rank : 17) NC score 0.223472 (rank : 31)
Query Neighborhood Hits 100 Target Neighborhood Hits 121 Shared Neighborhood Hits 43
SwissProt Accessions Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9 Gene names Arntl, Bmal1
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).
HEY2_HUMAN
 
θ value 0.00102713 (rank : 18) NC score 0.321065 (rank : 15)
Query Neighborhood Hits 100 Target Neighborhood Hits 77 Shared Neighborhood Hits 38
SwissProt Accessions Q9UBP5 Gene names HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain
Architecture

No domain graphic available

Description Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).
HEY2_MOUSE
 
θ value 0.00134147 (rank : 19) NC score 0.320280 (rank : 16)
Query Neighborhood Hits 100 Target Neighborhood Hits 80 Shared Neighborhood Hits 38
SwissProt Accessions Q9QUS4, Q3TZ99, Q8CD44 Gene names Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain
Architecture

No domain graphic available

Description Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).
CLOCK_MOUSE
 
θ value 0.00390308 (rank : 20) NC score 0.196144 (rank : 36)
Query Neighborhood Hits 100 Target Neighborhood Hits 148 Shared Neighborhood Hits 38
SwissProt Accessions O08785 Gene names Clock
Domain
Architecture
Description Circadian locomoter output cycles protein kaput (mCLOCK).
MYCS_MOUSE
 
θ value 0.00390308 (rank : 21) NC score 0.286660 (rank : 20)
Query Neighborhood Hits 100 Target Neighborhood Hits 83 Shared Neighborhood Hits 35
SwissProt Accessions Q9Z304 Gene names Mycs
Domain
Architecture
Description Protein S-myc.
MYC_HUMAN
 
θ value 0.00390308 (rank : 22) NC score 0.289489 (rank : 19)
Query Neighborhood Hits 100 Target Neighborhood Hits 146 Shared Neighborhood Hits 39
SwissProt Accessions P01106, P01107, Q14026 Gene names MYC
Domain
Architecture
Description Myc proto-oncogene protein (c-Myc) (Transcription factor p64).
TFE3_HUMAN
 
θ value 0.00390308 (rank : 23) NC score 0.325189 (rank : 14)
Query Neighborhood Hits 100 Target Neighborhood Hits 190 Shared Neighborhood Hits 52
SwissProt Accessions P19532, Q92757, Q92758, Q99964 Gene names TFE3
Domain
Architecture
Description Transcription factor E3.
MYC_MOUSE
 
θ value 0.00509761 (rank : 24) NC score 0.289930 (rank : 17)
Query Neighborhood Hits 100 Target Neighborhood Hits 125 Shared Neighborhood Hits 35
SwissProt Accessions P01108, P70247, Q3UM70, Q61422 Gene names Myc
Domain
Architecture
Description Myc proto-oncogene protein (c-Myc) (Transcription factor p64).
CLOCK_HUMAN
 
θ value 0.00665767 (rank : 25) NC score 0.192989 (rank : 37)
Query Neighborhood Hits 100 Target Neighborhood Hits 127 Shared Neighborhood Hits 36
SwissProt Accessions O15516, O14516, Q9UIT8 Gene names CLOCK, KIAA0334
Domain
Architecture
Description Circadian locomoter output cycles protein kaput (hCLOCK).
MYO10_HUMAN
 
θ value 0.0431538 (rank : 26) NC score 0.036859 (rank : 128)
Query Neighborhood Hits 100 Target Neighborhood Hits 920 Shared Neighborhood Hits 25
SwissProt Accessions Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6 Gene names MYO10
Domain
Architecture
Description Myosin-10 (Myosin X).
HEN2_HUMAN
 
θ value 0.0563607 (rank : 27) NC score 0.135634 (rank : 49)
Query Neighborhood Hits 100 Target Neighborhood Hits 83 Shared Neighborhood Hits 20
SwissProt Accessions Q02577 Gene names NHLH2, HEN2
Domain
Architecture
Description Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).
TCFL5_HUMAN
 
θ value 0.0563607 (rank : 28) NC score 0.204771 (rank : 35)
Query Neighborhood Hits 100 Target Neighborhood Hits 43 Shared Neighborhood Hits 24
SwissProt Accessions Q9UL49, O94771, Q9BYW0 Gene names TCFL5, CHA, E2BP1
Domain
Architecture

No domain graphic available

Description Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).
HEN2_MOUSE
 
θ value 0.0736092 (rank : 29) NC score 0.133771 (rank : 51)
Query Neighborhood Hits 100 Target Neighborhood Hits 83 Shared Neighborhood Hits 20
SwissProt Accessions Q64221 Gene names Nhlh2, Hen2
Domain
Architecture
Description Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).
TRIPB_HUMAN
 
θ value 0.0736092 (rank : 30) NC score 0.046095 (rank : 125)
Query Neighborhood Hits 100 Target Neighborhood Hits 1587 Shared Neighborhood Hits 35
SwissProt Accessions Q15643, O14689, O15154, O95949 Gene names TRIP11, CEV14
Domain
Architecture

No domain graphic available

Description Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).
MYCL1_MOUSE
 
θ value 0.0961366 (rank : 31) NC score 0.235145 (rank : 28)
Query Neighborhood Hits 100 Target Neighborhood Hits 123 Shared Neighborhood Hits 39
SwissProt Accessions P10166, Q5FWI7 Gene names Mycl1, Lmyc1, Mycl
Domain
Architecture
Description L-myc-1 proto-oncogene protein.
MYCN_MOUSE
 
θ value 0.0961366 (rank : 32) NC score 0.255636 (rank : 25)
Query Neighborhood Hits 100 Target Neighborhood Hits 125 Shared Neighborhood Hits 36
SwissProt Accessions P03966, Q61978 Gene names Mycn, Nmyc, Nmyc1
Domain
Architecture
Description N-myc proto-oncogene protein.
MYCN_HUMAN
 
θ value 0.125558 (rank : 33) NC score 0.270075 (rank : 24)
Query Neighborhood Hits 100 Target Neighborhood Hits 127 Shared Neighborhood Hits 35
SwissProt Accessions P04198, Q6LDT9 Gene names MYCN, NMYC
Domain
Architecture
Description N-myc proto-oncogene protein.
ERBB3_HUMAN
 
θ value 0.163984 (rank : 34) NC score 0.015093 (rank : 155)
Query Neighborhood Hits 100 Target Neighborhood Hits 918 Shared Neighborhood Hits 7
SwissProt Accessions P21860 Gene names ERBB3, HER3
Domain
Architecture
Description Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).
MITF_HUMAN
 
θ value 0.163984 (rank : 35) NC score 0.280055 (rank : 22)
Query Neighborhood Hits 100 Target Neighborhood Hits 113 Shared Neighborhood Hits 48
SwissProt Accessions O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8 Gene names MITF
Domain
Architecture
Description Microphthalmia-associated transcription factor.
HEN1_MOUSE
 
θ value 0.21417 (rank : 36) NC score 0.124480 (rank : 54)
Query Neighborhood Hits 100 Target Neighborhood Hits 86 Shared Neighborhood Hits 20
SwissProt Accessions Q02576 Gene names Nhlh1, Hen1
Domain
Architecture
Description Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).
MYCL1_HUMAN
 
θ value 0.21417 (rank : 37) NC score 0.232636 (rank : 29)
Query Neighborhood Hits 100 Target Neighborhood Hits 146 Shared Neighborhood Hits 40
SwissProt Accessions P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9 Gene names MYCL1, LMYC, MYCL
Domain
Architecture
Description L-myc-1 proto-oncogene protein.
TFEB_MOUSE
 
θ value 0.21417 (rank : 38) NC score 0.241411 (rank : 26)
Query Neighborhood Hits 100 Target Neighborhood Hits 119 Shared Neighborhood Hits 43
SwissProt Accessions Q9R210 Gene names Tfeb, Tcfeb
Domain
Architecture
Description Transcription factor EB.
BHLH3_HUMAN
 
θ value 0.279714 (rank : 39) NC score 0.205543 (rank : 33)
Query Neighborhood Hits 100 Target Neighborhood Hits 106 Shared Neighborhood Hits 34
SwissProt Accessions Q9C0J9 Gene names BHLHB3, DEC2, SHARP1
Domain
Architecture
Description Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).
BHLH3_MOUSE
 
θ value 0.279714 (rank : 40) NC score 0.204986 (rank : 34)
Query Neighborhood Hits 100 Target Neighborhood Hits 70 Shared Neighborhood Hits 34
SwissProt Accessions Q99PV5 Gene names Bhlhb3, Dec2
Domain
Architecture
Description Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).
FIGLA_HUMAN
 
θ value 0.365318 (rank : 41) NC score 0.147954 (rank : 47)
Query Neighborhood Hits 100 Target Neighborhood Hits 108 Shared Neighborhood Hits 26
SwissProt Accessions Q6QHK4 Gene names FIGLA
Domain
Architecture

No domain graphic available

Description Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).
MITF_MOUSE
 
θ value 0.365318 (rank : 42) NC score 0.274097 (rank : 23)
Query Neighborhood Hits 100 Target Neighborhood Hits 115 Shared Neighborhood Hits 49
SwissProt Accessions Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9 Gene names Mitf, Bw, Mi, Vit
Domain
Architecture
Description Microphthalmia-associated transcription factor.
MYH8_MOUSE
 
θ value 0.365318 (rank : 43) NC score 0.029613 (rank : 142)
Query Neighborhood Hits 100 Target Neighborhood Hits 1600 Shared Neighborhood Hits 35
SwissProt Accessions P13542, Q5SX36 Gene names Myh8, Myhsp
Domain
Architecture

No domain graphic available

Description Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).
NPAS2_HUMAN
 
θ value 0.365318 (rank : 44) NC score 0.159794 (rank : 45)
Query Neighborhood Hits 100 Target Neighborhood Hits 150 Shared Neighborhood Hits 32
SwissProt Accessions Q99743, Q99629 Gene names NPAS2
Domain
Architecture
Description Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).
NPAS2_MOUSE
 
θ value 0.365318 (rank : 45) NC score 0.159039 (rank : 46)
Query Neighborhood Hits 100 Target Neighborhood Hits 132 Shared Neighborhood Hits 32
SwissProt Accessions P97460 Gene names Npas2
Domain
Architecture
Description Neuronal PAS domain-containing protein 2 (Neuronal PAS2).
PHAR2_HUMAN
 
θ value 0.365318 (rank : 46) NC score 0.057834 (rank : 107)
Query Neighborhood Hits 100 Target Neighborhood Hits 208 Shared Neighborhood Hits 3
SwissProt Accessions O75167, Q68DM2 Gene names PHACTR2, C6orf56, KIAA0680
Domain
Architecture

No domain graphic available

Description Phosphatase and actin regulator 2.
BHLH2_HUMAN
 
θ value 0.47712 (rank : 47) NC score 0.185586 (rank : 38)
Query Neighborhood Hits 100 Target Neighborhood Hits 80 Shared Neighborhood Hits 36
SwissProt Accessions O14503, Q96TD3 Gene names BHLHB2, DEC1, SHARP2, STRA13
Domain
Architecture
Description Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).
CENPE_HUMAN
 
θ value 0.47712 (rank : 48) NC score 0.027522 (rank : 145)
Query Neighborhood Hits 100 Target Neighborhood Hits 2060 Shared Neighborhood Hits 38
SwissProt Accessions Q02224 Gene names CENPE
Domain
Architecture
Description Centromeric protein E (CENP-E).
TFEB_HUMAN
 
θ value 0.47712 (rank : 49) NC score 0.237695 (rank : 27)
Query Neighborhood Hits 100 Target Neighborhood Hits 111 Shared Neighborhood Hits 43
SwissProt Accessions P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8 Gene names TFEB
Domain
Architecture
Description Transcription factor EB.
MDN1_HUMAN
 
θ value 0.62314 (rank : 50) NC score 0.045910 (rank : 126)
Query Neighborhood Hits 100 Target Neighborhood Hits 662 Shared Neighborhood Hits 11
SwissProt Accessions Q9NU22, O15019 Gene names MDN1, KIAA0301
Domain
Architecture
Description Midasin (MIDAS-containing protein).
TAL1_HUMAN
 
θ value 0.62314 (rank : 51) NC score 0.113339 (rank : 57)
Query Neighborhood Hits 100 Target Neighborhood Hits 112 Shared Neighborhood Hits 29
SwissProt Accessions P17542 Gene names TAL1, SCL, TCL5
Domain
Architecture
Description T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).
TAL1_MOUSE
 
θ value 0.62314 (rank : 52) NC score 0.112166 (rank : 58)
Query Neighborhood Hits 100 Target Neighborhood Hits 110 Shared Neighborhood Hits 29
SwissProt Accessions P22091 Gene names Tal1, Scl, Tal-1
Domain
Architecture
Description T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).
BHLH2_MOUSE
 
θ value 0.813845 (rank : 53) NC score 0.176044 (rank : 39)
Query Neighborhood Hits 100 Target Neighborhood Hits 70 Shared Neighborhood Hits 32
SwissProt Accessions O35185, P97289 Gene names Bhlhb2, Clast5, Stra13
Domain
Architecture
Description Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).
FIGLA_MOUSE
 
θ value 0.813845 (rank : 54) NC score 0.146946 (rank : 48)
Query Neighborhood Hits 100 Target Neighborhood Hits 100 Shared Neighborhood Hits 26
SwissProt Accessions O55208 Gene names Figla
Domain
Architecture

No domain graphic available

Description Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).
ERBB3_MOUSE
 
θ value 1.06291 (rank : 55) NC score 0.012421 (rank : 158)
Query Neighborhood Hits 100 Target Neighborhood Hits 898 Shared Neighborhood Hits 8
SwissProt Accessions Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317 Gene names Erbb3
Domain
Architecture

No domain graphic available

Description Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).
EZRI_MOUSE
 
θ value 1.06291 (rank : 56) NC score 0.030947 (rank : 137)
Query Neighborhood Hits 100 Target Neighborhood Hits 693 Shared Neighborhood Hits 20
SwissProt Accessions P26040, Q80ZT8, Q9DCI1 Gene names Vil2
Domain
Architecture
Description Ezrin (p81) (Cytovillin) (Villin-2).
RBBP6_MOUSE
 
θ value 1.06291 (rank : 57) NC score 0.039850 (rank : 127)
Query Neighborhood Hits 100 Target Neighborhood Hits 1014 Shared Neighborhood Hits 17
SwissProt Accessions P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399 Gene names Rbbp6, P2pr, Pact
Domain
Architecture

No domain graphic available

Description Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).
RBCC1_HUMAN
 
θ value 1.38821 (rank : 58) NC score 0.029658 (rank : 141)
Query Neighborhood Hits 100 Target Neighborhood Hits 1023 Shared Neighborhood Hits 28
SwissProt Accessions Q8TDY2, Q8WVU9, Q92601 Gene names RB1CC1, KIAA0203, RBICC
Domain
Architecture

No domain graphic available

Description RB1-inducible coiled-coil protein 1.
BRD2_HUMAN
 
θ value 1.81305 (rank : 59) NC score 0.025962 (rank : 148)
Query Neighborhood Hits 100 Target Neighborhood Hits 242 Shared Neighborhood Hits 7
SwissProt Accessions P25440, O00699, O00700, Q15310, Q5STC9, Q969U4 Gene names BRD2, KIAA9001, RING3
Domain
Architecture
Description Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).
ITF2_MOUSE
 
θ value 1.81305 (rank : 60) NC score 0.048880 (rank : 123)
Query Neighborhood Hits 100 Target Neighborhood Hits 154 Shared Neighborhood Hits 19
SwissProt Accessions Q60722, Q60721, Q62211, Q64072, Q80UE8 Gene names Tcf4, Itf2, Sef2
Domain
Architecture
Description Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).
LAMB2_HUMAN
 
θ value 1.81305 (rank : 61) NC score 0.011064 (rank : 161)
Query Neighborhood Hits 100 Target Neighborhood Hits 692 Shared Neighborhood Hits 14
SwissProt Accessions P55268, Q16321 Gene names LAMB2, LAMS
Domain
Architecture
Description Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).
NCOA1_HUMAN
 
θ value 1.81305 (rank : 62) NC score 0.093251 (rank : 62)
Query Neighborhood Hits 100 Target Neighborhood Hits 198 Shared Neighborhood Hits 26
SwissProt Accessions Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3 Gene names NCOA1, SRC1
Domain
Architecture

No domain graphic available

Description Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).
NCOA1_MOUSE
 
θ value 1.81305 (rank : 63) NC score 0.093059 (rank : 63)
Query Neighborhood Hits 100 Target Neighborhood Hits 196 Shared Neighborhood Hits 24
SwissProt Accessions P70365, P70366, Q61202, Q8CBI9 Gene names Ncoa1, Src1
Domain
Architecture

No domain graphic available

Description Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).
PLXD1_HUMAN
 
θ value 1.81305 (rank : 64) NC score 0.018641 (rank : 154)
Query Neighborhood Hits 100 Target Neighborhood Hits 89 Shared Neighborhood Hits 3
SwissProt Accessions Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2 Gene names PLXND1, KIAA0620
Domain
Architecture

No domain graphic available

Description Plexin-D1 precursor.
EZRI_HUMAN
 
θ value 2.36792 (rank : 65) NC score 0.028139 (rank : 143)
Query Neighborhood Hits 100 Target Neighborhood Hits 663 Shared Neighborhood Hits 19
SwissProt Accessions P15311, P23714, Q96CU8, Q9NSJ4 Gene names VIL2
Domain
Architecture
Description Ezrin (p81) (Cytovillin) (Villin-2).
ID1_HUMAN
 
θ value 2.36792 (rank : 66) NC score 0.089102 (rank : 69)
Query Neighborhood Hits 100 Target Neighborhood Hits 63 Shared Neighborhood Hits 20
SwissProt Accessions P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109 Gene names ID1, ID
Domain
Architecture
Description DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).
ID1_MOUSE
 
θ value 2.36792 (rank : 67) NC score 0.092156 (rank : 64)
Query Neighborhood Hits 100 Target Neighborhood Hits 64 Shared Neighborhood Hits 20
SwissProt Accessions P20067, Q61101, Q9D897 Gene names Id1, Id, Id-1, Idb1
Domain
Architecture
Description DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).
TULP1_MOUSE
 
θ value 2.36792 (rank : 68) NC score 0.030106 (rank : 139)
Query Neighborhood Hits 100 Target Neighborhood Hits 146 Shared Neighborhood Hits 6
SwissProt Accessions Q9Z273 Gene names Tulp1
Domain
Architecture
Description Tubby-related protein 1 (Tubby-like protein 1).
CLK1_HUMAN
 
θ value 3.0926 (rank : 69) NC score 0.004127 (rank : 162)
Query Neighborhood Hits 100 Target Neighborhood Hits 756 Shared Neighborhood Hits 6
SwissProt Accessions P49759 Gene names CLK1, CLK
Domain
Architecture
Description Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1).
HEN1_HUMAN
 
θ value 3.0926 (rank : 70) NC score 0.095645 (rank : 61)
Query Neighborhood Hits 100 Target Neighborhood Hits 88 Shared Neighborhood Hits 20
SwissProt Accessions Q02575 Gene names NHLH1, HEN1
Domain
Architecture
Description Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).
HOME2_MOUSE
 
θ value 3.0926 (rank : 71) NC score 0.033988 (rank : 133)
Query Neighborhood Hits 100 Target Neighborhood Hits 882 Shared Neighborhood Hits 26
SwissProt Accessions Q9QWW1, O89025, Q9Z0E4 Gene names Homer2, Vesl2
Domain
Architecture
Description Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).
NGN1_MOUSE
 
θ value 3.0926 (rank : 72) NC score 0.047019 (rank : 124)
Query Neighborhood Hits 100 Target Neighborhood Hits 87 Shared Neighborhood Hits 15
SwissProt Accessions P70660 Gene names Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain
Architecture
Description Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).
RB6I2_HUMAN
 
θ value 3.0926 (rank : 73) NC score 0.030389 (rank : 138)
Query Neighborhood Hits 100 Target Neighborhood Hits 1584 Shared Neighborhood Hits 31
SwissProt Accessions Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1 Gene names ERC1, ELKS, KIAA1081, RAB6IP2
Domain
Architecture

No domain graphic available

Description ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).
RB6I2_MOUSE
 
θ value 3.0926 (rank : 74) NC score 0.029704 (rank : 140)
Query Neighborhood Hits 100 Target Neighborhood Hits 1433 Shared Neighborhood Hits 32
SwissProt Accessions Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2 Gene names Erc1, Cast2, Kiaa1081, Rab6ip2
Domain
Architecture

No domain graphic available

Description ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).
CCD11_MOUSE
 
θ value 4.03905 (rank : 75) NC score 0.028002 (rank : 144)
Query Neighborhood Hits 100 Target Neighborhood Hits 498 Shared Neighborhood Hits 18
SwissProt Accessions Q9D439 Gene names Ccdc11
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 11.
HOME2_HUMAN
 
θ value 4.03905 (rank : 76) NC score 0.035324 (rank : 131)
Query Neighborhood Hits 100 Target Neighborhood Hits 532 Shared Neighborhood Hits 18
SwissProt Accessions Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7 Gene names HOMER2
Domain
Architecture
Description Homer protein homolog 2 (Homer-2) (Cupidin).
INCE_HUMAN
 
θ value 4.03905 (rank : 77) NC score 0.026236 (rank : 147)
Query Neighborhood Hits 100 Target Neighborhood Hits 978 Shared Neighborhood Hits 24
SwissProt Accessions Q9NQS7, Q5Y192 Gene names INCENP
Domain
Architecture
Description Inner centromere protein.
TRAK2_HUMAN
 
θ value 4.03905 (rank : 78) NC score 0.035484 (rank : 130)
Query Neighborhood Hits 100 Target Neighborhood Hits 476 Shared Neighborhood Hits 19
SwissProt Accessions O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6 Gene names TRAK2, ALS2CR3, KIAA0549
Domain
Architecture
Description Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).
ARNT2_HUMAN
 
θ value 5.27518 (rank : 79) NC score 0.160457 (rank : 44)
Query Neighborhood Hits 100 Target Neighborhood Hits 109 Shared Neighborhood Hits 43
SwissProt Accessions Q9HBZ2, O15024 Gene names ARNT2, KIAA0307
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).
ARNT2_MOUSE
 
θ value 5.27518 (rank : 80) NC score 0.161243 (rank : 43)
Query Neighborhood Hits 100 Target Neighborhood Hits 115 Shared Neighborhood Hits 43
SwissProt Accessions Q61324 Gene names Arnt2
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).
ARNT_HUMAN
 
θ value 5.27518 (rank : 81) NC score 0.168694 (rank : 40)
Query Neighborhood Hits 100 Target Neighborhood Hits 109 Shared Neighborhood Hits 43
SwissProt Accessions P27540 Gene names ARNT
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).
ARNT_MOUSE
 
θ value 5.27518 (rank : 82) NC score 0.166800 (rank : 42)
Query Neighborhood Hits 100 Target Neighborhood Hits 213 Shared Neighborhood Hits 44
SwissProt Accessions P53762, Q60661 Gene names Arnt
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).
CDC37_MOUSE
 
θ value 5.27518 (rank : 83) NC score 0.033953 (rank : 134)
Query Neighborhood Hits 100 Target Neighborhood Hits 359 Shared Neighborhood Hits 20
SwissProt Accessions Q61081, Q3TGP0 Gene names Cdc37
Domain
Architecture
Description Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).
CTRO_HUMAN
 
θ value 5.27518 (rank : 84) NC score 0.011732 (rank : 160)
Query Neighborhood Hits 100 Target Neighborhood Hits 2092 Shared Neighborhood Hits 31
SwissProt Accessions O14578, Q6XUH8, Q86UQ9, Q9UPZ7 Gene names CIT, KIAA0949, STK21
Domain
Architecture

No domain graphic available

Description Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).
FOSL1_HUMAN
 
θ value 5.27518 (rank : 85) NC score 0.033409 (rank : 135)
Query Neighborhood Hits 100 Target Neighborhood Hits 112 Shared Neighborhood Hits 7
SwissProt Accessions P15407 Gene names FOSL1, FRA1
Domain
Architecture
Description Fos-related antigen 1 (FRA-1).
FOSL1_MOUSE
 
θ value 5.27518 (rank : 86) NC score 0.034192 (rank : 132)
Query Neighborhood Hits 100 Target Neighborhood Hits 113 Shared Neighborhood Hits 9
SwissProt Accessions P48755, O35285 Gene names Fosl1, Fra1
Domain
Architecture
Description Fos-related antigen 1 (FRA-1).
MYF5_HUMAN
 
θ value 5.27518 (rank : 87) NC score 0.053839 (rank : 113)
Query Neighborhood Hits 100 Target Neighborhood Hits 80 Shared Neighborhood Hits 19
SwissProt Accessions P13349 Gene names MYF5
Domain
Architecture
Description Myogenic factor 5 (Myf-5).
MYF5_MOUSE
 
θ value 5.27518 (rank : 88) NC score 0.053610 (rank : 115)
Query Neighborhood Hits 100 Target Neighborhood Hits 77 Shared Neighborhood Hits 19
SwissProt Accessions P24699, Q543W7 Gene names Myf5, Myf-5
Domain
Architecture
Description Myogenic factor 5 (Myf-5).
PCDGM_HUMAN
 
θ value 5.27518 (rank : 89) NC score 0.001649 (rank : 163)
Query Neighborhood Hits 100 Target Neighborhood Hits 152 Shared Neighborhood Hits 2
SwissProt Accessions Q9Y5F6, Q9Y5C2 Gene names PCDHGC5
Domain
Architecture
Description Protocadherin gamma C5 precursor (PCDH-gamma-C5).
SPTN2_HUMAN
 
θ value 5.27518 (rank : 90) NC score 0.013041 (rank : 157)
Query Neighborhood Hits 100 Target Neighborhood Hits 535 Shared Neighborhood Hits 21
SwissProt Accessions O15020, O14872, O14873 Gene names SPTBN2, KIAA0302
Domain
Architecture
Description Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).
XLR_MOUSE
 
θ value 5.27518 (rank : 91) NC score 0.035703 (rank : 129)
Query Neighborhood Hits 100 Target Neighborhood Hits 73 Shared Neighborhood Hits 6
SwissProt Accessions P05531 Gene names Xlr
Domain
Architecture
Description X-linked lymphocyte-regulated protein PM1.
CENPF_HUMAN
 
θ value 6.88961 (rank : 92) NC score 0.024434 (rank : 151)
Query Neighborhood Hits 100 Target Neighborhood Hits 1932 Shared Neighborhood Hits 39
SwissProt Accessions P49454, Q13171, Q13246 Gene names CENPF
Domain
Architecture
Description Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).
CTRO_MOUSE
 
θ value 6.88961 (rank : 93) NC score 0.011986 (rank : 159)
Query Neighborhood Hits 100 Target Neighborhood Hits 2344 Shared Neighborhood Hits 32
SwissProt Accessions P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1 Gene names Cit
Domain
Architecture
Description Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).
CV019_HUMAN
 
θ value 6.88961 (rank : 94) NC score 0.033079 (rank : 136)
Query Neighborhood Hits 100 Target Neighborhood Hits 62 Shared Neighborhood Hits 4
SwissProt Accessions Q13769, O60839, Q9UPZ5 Gene names C22orf19, KIAA0983
Domain
Architecture

No domain graphic available

Description Protein C22orf19 (NF2/meningioma region protein pK1.3) (Placental protein 39.2).
MFAP1_MOUSE
 
θ value 6.88961 (rank : 95) NC score 0.025348 (rank : 150)
Query Neighborhood Hits 100 Target Neighborhood Hits 353 Shared Neighborhood Hits 14
SwissProt Accessions Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5 Gene names Mfap1
Domain
Architecture

No domain graphic available

Description Microfibrillar-associated protein 1.
MYH13_HUMAN
 
θ value 6.88961 (rank : 96) NC score 0.022960 (rank : 152)
Query Neighborhood Hits 100 Target Neighborhood Hits 1504 Shared Neighborhood Hits 29
SwissProt Accessions Q9UKX3, O95252 Gene names MYH13
Domain
Architecture
Description Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).
CCD27_MOUSE
 
θ value 8.99809 (rank : 97) NC score 0.026874 (rank : 146)
Query Neighborhood Hits 100 Target Neighborhood Hits 461 Shared Neighborhood Hits 16
SwissProt Accessions Q3V036 Gene names Ccdc27
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 27.
GOGA1_MOUSE
 
θ value 8.99809 (rank : 98) NC score 0.025520 (rank : 149)
Query Neighborhood Hits 100 Target Neighborhood Hits 994 Shared Neighborhood Hits 29
SwissProt Accessions Q9CW79, Q80YB0 Gene names Golga1
Domain
Architecture
Description Golgin subfamily A member 1 (Golgin-97).
RBBP6_HUMAN
 
θ value 8.99809 (rank : 99) NC score 0.022892 (rank : 153)
Query Neighborhood Hits 100 Target Neighborhood Hits 1135 Shared Neighborhood Hits 19
SwissProt Accessions Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4 Gene names RBBP6, P2PR, PACT, RBQ1
Domain
Architecture

No domain graphic available

Description Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).
SAS10_HUMAN
 
θ value 8.99809 (rank : 100) NC score 0.013272 (rank : 156)
Query Neighborhood Hits 100 Target Neighborhood Hits 102 Shared Neighborhood Hits 2
SwissProt Accessions Q9NQZ2, Q6FI82 Gene names CRLZ1, SAS10
Domain
Architecture

No domain graphic available

Description Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).
AHR_HUMAN
 
θ value θ > 10 (rank : 101) NC score 0.066840 (rank : 84)
Query Neighborhood Hits 100 Target Neighborhood Hits 47 Shared Neighborhood Hits 14
SwissProt Accessions P35869, Q13728, Q13803, Q13804 Gene names AHR
Domain
Architecture
Description Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).
AHR_MOUSE
 
θ value θ > 10 (rank : 102) NC score 0.065402 (rank : 88)
Query Neighborhood Hits 100 Target Neighborhood Hits 55 Shared Neighborhood Hits 12
SwissProt Accessions P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1 Gene names Ahr
Domain
Architecture
Description Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).
ASCL1_HUMAN
 
θ value θ > 10 (rank : 103) NC score 0.053840 (rank : 112)
Query Neighborhood Hits 100 Target Neighborhood Hits 94 Shared Neighborhood Hits 22
SwissProt Accessions P50553, Q9BQ30 Gene names ASCL1, ASH1
Domain
Architecture
Description Achaete-scute homolog 1 (HASH1).
ASCL1_MOUSE
 
θ value θ > 10 (rank : 104) NC score 0.050592 (rank : 121)
Query Neighborhood Hits 100 Target Neighborhood Hits 97 Shared Neighborhood Hits 22
SwissProt Accessions Q02067 Gene names Ascl1, Ash1, Mash-1, Mash1
Domain
Architecture
Description Achaete-scute homolog 1 (Mash-1).
ASCL2_MOUSE
 
θ value θ > 10 (rank : 105) NC score 0.050823 (rank : 120)
Query Neighborhood Hits 100 Target Neighborhood Hits 98 Shared Neighborhood Hits 22
SwissProt Accessions O35885, Q9WUJ7 Gene names Ascl2, Mash2
Domain
Architecture
Description Achaete-scute homolog 2 (Mash-2).
BHLH8_HUMAN
 
θ value θ > 10 (rank : 106) NC score 0.080252 (rank : 75)
Query Neighborhood Hits 100 Target Neighborhood Hits 123 Shared Neighborhood Hits 32
SwissProt Accessions Q7RTS1 Gene names BHLHB8, MIST1
Domain
Architecture

No domain graphic available

Description Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).
BHLH8_MOUSE
 
θ value θ > 10 (rank : 107) NC score 0.080931 (rank : 74)
Query Neighborhood Hits 100 Target Neighborhood Hits 107 Shared Neighborhood Hits 32
SwissProt Accessions Q9QYC3, Q9QYE4 Gene names Bhlhb8, Mist1
Domain
Architecture

No domain graphic available

Description Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).
EPAS1_HUMAN
 
θ value θ > 10 (rank : 108) NC score 0.067571 (rank : 83)
Query Neighborhood Hits 100 Target Neighborhood Hits 76 Shared Neighborhood Hits 13
SwissProt Accessions Q99814, Q86VA2, Q99630 Gene names EPAS1, HIF2A
Domain
Architecture
Description Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).
EPAS1_MOUSE
 
θ value θ > 10 (rank : 109) NC score 0.066095 (rank : 85)
Query Neighborhood Hits 100 Target Neighborhood Hits 94 Shared Neighborhood Hits 12
SwissProt Accessions P97481, O08787, O55046 Gene names Epas1, Hif2a
Domain
Architecture
Description Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).
HAND1_HUMAN
 
θ value θ > 10 (rank : 110) NC score 0.068336 (rank : 82)
Query Neighborhood Hits 100 Target Neighborhood Hits 100 Shared Neighborhood Hits 31
SwissProt Accessions O96004 Gene names HAND1, EHAND
Domain
Architecture
Description Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).
HAND1_MOUSE
 
θ value θ > 10 (rank : 111) NC score 0.065468 (rank : 87)
Query Neighborhood Hits 100 Target Neighborhood Hits 107 Shared Neighborhood Hits 33
SwissProt Accessions Q64279, Q61099 Gene names Hand1, Ehand, Hxt, Thing1
Domain
Architecture
Description Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).
HAND2_HUMAN
 
θ value θ > 10 (rank : 112) NC score 0.074297 (rank : 80)
Query Neighborhood Hits 100 Target Neighborhood Hits 99 Shared Neighborhood Hits 28
SwissProt Accessions P61296, O95300, O95301, P97833 Gene names HAND2, DHAND
Domain
Architecture
Description Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).
HAND2_MOUSE
 
θ value θ > 10 (rank : 113) NC score 0.074297 (rank : 81)
Query Neighborhood Hits 100 Target Neighborhood Hits 99 Shared Neighborhood Hits 28
SwissProt Accessions Q61039, Q61100 Gene names Hand2, Dhand, Hed, Thing2
Domain
Architecture
Description Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).
HES1_HUMAN
 
θ value θ > 10 (rank : 114) NC score 0.129233 (rank : 53)
Query Neighborhood Hits 100 Target Neighborhood Hits 76 Shared Neighborhood Hits 26
SwissProt Accessions Q14469 Gene names HES1, HL, HRY
Domain
Architecture
Description Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).
HES1_MOUSE
 
θ value θ > 10 (rank : 115) NC score 0.129535 (rank : 52)
Query Neighborhood Hits 100 Target Neighborhood Hits 78 Shared Neighborhood Hits 26
SwissProt Accessions P35428 Gene names Hes1, Hes-1
Domain
Architecture
Description Transcription factor HES-1 (Hairy and enhancer of split 1).
HES2_HUMAN
 
θ value θ > 10 (rank : 116) NC score 0.084665 (rank : 72)
Query Neighborhood Hits 100 Target Neighborhood Hits 38 Shared Neighborhood Hits 10
SwissProt Accessions Q9Y543, Q96EN4, Q9Y542 Gene names HES2
Domain
Architecture
Description Transcription factor HES-2 (Hairy and enhancer of split 2).
HES2_MOUSE
 
θ value θ > 10 (rank : 117) NC score 0.089537 (rank : 67)
Query Neighborhood Hits 100 Target Neighborhood Hits 36 Shared Neighborhood Hits 12
SwissProt Accessions O54792 Gene names Hes2
Domain
Architecture
Description Transcription factor HES-2 (Hairy and enhancer of split 2).
HES3_MOUSE
 
θ value θ > 10 (rank : 118) NC score 0.081597 (rank : 73)
Query Neighborhood Hits 100 Target Neighborhood Hits 38 Shared Neighborhood Hits 14
SwissProt Accessions Q61657, O09083, O09150 Gene names Hes3, Hes-3
Domain
Architecture
Description Transcription factor HES-3 (Hairy and enhancer of split 3).
HES4_HUMAN
 
θ value θ > 10 (rank : 119) NC score 0.135424 (rank : 50)
Query Neighborhood Hits 100 Target Neighborhood Hits 58 Shared Neighborhood Hits 31
SwissProt Accessions Q9HCC6 Gene names HES4
Domain
Architecture
Description Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).
HES5_MOUSE
 
θ value θ > 10 (rank : 120) NC score 0.123772 (rank : 55)
Query Neighborhood Hits 100 Target Neighborhood Hits 38 Shared Neighborhood Hits 17
SwissProt Accessions P70120, Q8BVI1 Gene names Hes5, Hes-5
Domain
Architecture
Description Transcription factor HES-5 (Hairy and enhancer of split 5).
HES6_HUMAN
 
θ value θ > 10 (rank : 121) NC score 0.089538 (rank : 66)
Query Neighborhood Hits 100 Target Neighborhood Hits 49 Shared Neighborhood Hits 13
SwissProt Accessions Q96HZ4, Q8N2J2, Q96T93, Q9P2S3 Gene names HES6
Domain
Architecture

No domain graphic available

Description Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).
HES6_MOUSE
 
θ value θ > 10 (rank : 122) NC score 0.087281 (rank : 70)
Query Neighborhood Hits 100 Target Neighborhood Hits 49 Shared Neighborhood Hits 12
SwissProt Accessions Q9JHE6, Q3U2D7 Gene names Hes6
Domain
Architecture

No domain graphic available

Description Transcription cofactor HES-6 (Hairy and enhancer of split 6).
HES7_HUMAN
 
θ value θ > 10 (rank : 123) NC score 0.077041 (rank : 77)
Query Neighborhood Hits 100 Target Neighborhood Hits 72 Shared Neighborhood Hits 20
SwissProt Accessions Q9BYE0 Gene names HES7
Domain
Architecture

No domain graphic available

Description Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).
HES7_MOUSE
 
θ value θ > 10 (rank : 124) NC score 0.076462 (rank : 78)
Query Neighborhood Hits 100 Target Neighborhood Hits 72 Shared Neighborhood Hits 19
SwissProt Accessions Q8BKT2, Q99JA6 Gene names Hes7
Domain
Architecture

No domain graphic available

Description Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).
HIF1A_HUMAN
 
θ value θ > 10 (rank : 125) NC score 0.065831 (rank : 86)
Query Neighborhood Hits 100 Target Neighborhood Hits 118 Shared Neighborhood Hits 12
SwissProt Accessions Q16665, Q96PT9, Q9UPB1 Gene names HIF1A
Domain
Architecture
Description Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).
HIF1A_MOUSE
 
θ value θ > 10 (rank : 126) NC score 0.065290 (rank : 89)
Query Neighborhood Hits 100 Target Neighborhood Hits 90 Shared Neighborhood Hits 12
SwissProt Accessions Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8 Gene names Hif1a
Domain
Architecture
Description Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).
LYL1_HUMAN
 
θ value θ > 10 (rank : 127) NC score 0.061719 (rank : 100)
Query Neighborhood Hits 100 Target Neighborhood Hits 113 Shared Neighborhood Hits 22
SwissProt Accessions P12980, O76102 Gene names LYL1
Domain
Architecture
Description Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).
LYL1_MOUSE
 
θ value θ > 10 (rank : 128) NC score 0.059426 (rank : 104)
Query Neighborhood Hits 100 Target Neighborhood Hits 102 Shared Neighborhood Hits 20
SwissProt Accessions P27792 Gene names Lyl1, Lyl-1
Domain
Architecture
Description Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).
MAD1_MOUSE
 
θ value θ > 10 (rank : 129) NC score 0.063529 (rank : 98)
Query Neighborhood Hits 100 Target Neighborhood Hits 75 Shared Neighborhood Hits 26
SwissProt Accessions P50538, Q60798, Q61825 Gene names Mxd1, Mad, Mad1
Domain
Architecture
Description MAD protein (MAX dimerizer) (MAX dimerization protein 1).
MAD3_HUMAN
 
θ value θ > 10 (rank : 130) NC score 0.080152 (rank : 76)
Query Neighborhood Hits 100 Target Neighborhood Hits 92 Shared Neighborhood Hits 31
SwissProt Accessions Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3 Gene names MXD3, MAD3
Domain
Architecture

No domain graphic available

Description Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).
MAD3_MOUSE
 
θ value θ > 10 (rank : 131) NC score 0.074460 (rank : 79)
Query Neighborhood Hits 100 Target Neighborhood Hits 94 Shared Neighborhood Hits 29
SwissProt Accessions Q80US8, Q60947 Gene names Mxd3, Mad3
Domain
Architecture

No domain graphic available

Description Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).
MAD4_HUMAN
 
θ value θ > 10 (rank : 132) NC score 0.089160 (rank : 68)
Query Neighborhood Hits 100 Target Neighborhood Hits 94 Shared Neighborhood Hits 30
SwissProt Accessions Q14582, Q5TZX4 Gene names MXD4, MAD4
Domain
Architecture
Description Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).
MAD4_MOUSE
 
θ value θ > 10 (rank : 133) NC score 0.053711 (rank : 114)
Query Neighborhood Hits 100 Target Neighborhood Hits 65 Shared Neighborhood Hits 16
SwissProt Accessions Q60948 Gene names Mxd4, Mad4
Domain
Architecture
Description Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).
MNT_HUMAN
 
θ value θ > 10 (rank : 134) NC score 0.105122 (rank : 59)
Query Neighborhood Hits 100 Target Neighborhood Hits 496 Shared Neighborhood Hits 37
SwissProt Accessions Q99583 Gene names MNT, ROX
Domain
Architecture
Description Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).
MNT_MOUSE
 
θ value θ > 10 (rank : 135) NC score 0.103313 (rank : 60)
Query Neighborhood Hits 100 Target Neighborhood Hits 432 Shared Neighborhood Hits 38
SwissProt Accessions O08789, P97349 Gene names Mnt, Rox
Domain
Architecture
Description Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).
MXI1_HUMAN
 
θ value θ > 10 (rank : 136) NC score 0.087053 (rank : 71)
Query Neighborhood Hits 100 Target Neighborhood Hits 76 Shared Neighborhood Hits 28
SwissProt Accessions P50539, Q15887 Gene names MXI1
Domain
Architecture
Description MAX-interacting protein 1 (Protein MXI1).
MXI1_MOUSE
 
θ value θ > 10 (rank : 137) NC score 0.091477 (rank : 65)
Query Neighborhood Hits 100 Target Neighborhood Hits 109 Shared Neighborhood Hits 29
SwissProt Accessions P50540 Gene names Mxi1
Domain
Architecture
Description MAX-interacting protein 1 (Protein MXI1).
MYCB_MOUSE
 
θ value θ > 10 (rank : 138) NC score 0.116107 (rank : 56)
Query Neighborhood Hits 100 Target Neighborhood Hits 14 Shared Neighborhood Hits 7
SwissProt Accessions Q6P8Z1, Q9D6E3 Gene names Mycb, Bmyc
Domain
Architecture

No domain graphic available

Description Protein B-Myc.
MYCL2_HUMAN
 
θ value θ > 10 (rank : 139) NC score 0.166920 (rank : 41)
Query Neighborhood Hits 100 Target Neighborhood Hits 63 Shared Neighborhood Hits 22
SwissProt Accessions P12525 Gene names MYCL2
Domain
Architecture
Description L-myc-2 protein.
NCOA2_HUMAN
 
θ value θ > 10 (rank : 140) NC score 0.056464 (rank : 109)
Query Neighborhood Hits 100 Target Neighborhood Hits 281 Shared Neighborhood Hits 12
SwissProt Accessions Q15596 Gene names NCOA2, TIF2
Domain
Architecture
Description Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).
NCOA2_MOUSE
 
θ value θ > 10 (rank : 141) NC score 0.056864 (rank : 108)
Query Neighborhood Hits 100 Target Neighborhood Hits 281 Shared Neighborhood Hits 13
SwissProt Accessions Q61026, O09001, P97759 Gene names Ncoa2, Grip1, Tif2
Domain
Architecture
Description Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).
NCOA3_HUMAN
 
θ value θ > 10 (rank : 142) NC score 0.060957 (rank : 102)
Query Neighborhood Hits 100 Target Neighborhood Hits 171 Shared Neighborhood Hits 13
SwissProt Accessions Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7 Gene names NCOA3, AIB1, RAC3, TRAM1
Domain
Architecture
Description Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).
NCOA3_MOUSE
 
θ value θ > 10 (rank : 143) NC score 0.054624 (rank : 111)
Query Neighborhood Hits 100 Target Neighborhood Hits 203 Shared Neighborhood Hits 13
SwissProt Accessions O09000, Q9CRD5 Gene names Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain
Architecture
Description Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).
NPAS1_HUMAN
 
θ value θ > 10 (rank : 144) NC score 0.053426 (rank : 116)
Query Neighborhood Hits 100 Target Neighborhood Hits 77 Shared Neighborhood Hits 14
SwissProt Accessions Q99742, Q99632, Q9BY83 Gene names NPAS1
Domain
Architecture
Description Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).
NPAS1_MOUSE
 
θ value θ > 10 (rank : 145) NC score 0.055194 (rank : 110)
Query Neighborhood Hits 100 Target Neighborhood Hits 63 Shared Neighborhood Hits 15
SwissProt Accessions P97459 Gene names Npas1
Domain
Architecture
Description Neuronal PAS domain-containing protein 1 (Neuronal PAS1).
NPAS3_HUMAN
 
θ value θ > 10 (rank : 146) NC score 0.058502 (rank : 105)
Query Neighborhood Hits 100 Target Neighborhood Hits 81 Shared Neighborhood Hits 16
SwissProt Accessions Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8 Gene names NPAS3
Domain
Architecture
Description Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).
NPAS3_MOUSE
 
θ value θ > 10 (rank : 147) NC score 0.059552 (rank : 103)
Query Neighborhood Hits 100 Target Neighborhood Hits 103 Shared Neighborhood Hits 17
SwissProt Accessions Q9QZQ0, Q9EQP4 Gene names Npas3
Domain
Architecture
Description Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).
NPAS4_HUMAN
 
θ value θ > 10 (rank : 148) NC score 0.052586 (rank : 118)
Query Neighborhood Hits 100 Target Neighborhood Hits 214 Shared Neighborhood Hits 14
SwissProt Accessions Q8IUM7, Q8N8S5, Q8N9Q9 Gene names NPAS4, NXF
Domain
Architecture

No domain graphic available

Description Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).
PER2_MOUSE
 
θ value θ > 10 (rank : 149) NC score 0.050227 (rank : 122)
Query Neighborhood Hits 100 Target Neighborhood Hits 325 Shared Neighborhood Hits 14
SwissProt Accessions O54943, O54954 Gene names Per2
Domain
Architecture
Description Period circadian protein 2 (mPER2).
PTF1A_HUMAN
 
θ value θ > 10 (rank : 150) NC score 0.063103 (rank : 99)
Query Neighborhood Hits 100 Target Neighborhood Hits 95 Shared Neighborhood Hits 26
SwissProt Accessions Q7RTS3, Q9HC25 Gene names PTF1A, PTF1P48
Domain
Architecture

No domain graphic available

Description Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).
PTF1A_MOUSE
 
θ value θ > 10 (rank : 151) NC score 0.061716 (rank : 101)
Query Neighborhood Hits 100 Target Neighborhood Hits 100 Shared Neighborhood Hits 28
SwissProt Accessions Q9QX98, Q9QYF5, Q9QYF6 Gene names Ptf1a, Ptf1p48
Domain
Architecture

No domain graphic available

Description Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).
SCX_MOUSE
 
θ value θ > 10 (rank : 152) NC score 0.052729 (rank : 117)
Query Neighborhood Hits 100 Target Neighborhood Hits 82 Shared Neighborhood Hits 19
SwissProt Accessions Q64124 Gene names Scx
Domain
Architecture
Description Basic helix-loop-helix transcription factor scleraxis.
SIM1_HUMAN
 
θ value θ > 10 (rank : 153) NC score 0.063645 (rank : 97)
Query Neighborhood Hits 100 Target Neighborhood Hits 62 Shared Neighborhood Hits 16
SwissProt Accessions P81133, Q5TDP7 Gene names SIM1
Domain
Architecture
Description Single-minded homolog 1.
SIM1_MOUSE
 
θ value θ > 10 (rank : 154) NC score 0.063902 (rank : 94)
Query Neighborhood Hits 100 Target Neighborhood Hits 69 Shared Neighborhood Hits 16
SwissProt Accessions Q61045, O70284, P70183 Gene names Sim1
Domain
Architecture
Description Single-minded homolog 1 (mSIM1).
SIM2_HUMAN
 
θ value θ > 10 (rank : 155) NC score 0.064860 (rank : 90)
Query Neighborhood Hits 100 Target Neighborhood Hits 76 Shared Neighborhood Hits 16
SwissProt Accessions Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532 Gene names SIM2
Domain
Architecture
Description Single-minded homolog 2.
SIM2_MOUSE
 
θ value θ > 10 (rank : 156) NC score 0.064308 (rank : 93)
Query Neighborhood Hits 100 Target Neighborhood Hits 75 Shared Neighborhood Hits 17
SwissProt Accessions Q61079, O35391, Q61046, Q61904 Gene names Sim2
Domain
Architecture
Description Single-minded homolog 2 (SIM transcription factor) (mSIM).
SRBP2_HUMAN
 
θ value θ > 10 (rank : 157) NC score 0.216353 (rank : 32)
Query Neighborhood Hits 100 Target Neighborhood Hits 133 Shared Neighborhood Hits 41
SwissProt Accessions Q12772, Q9UH04 Gene names SREBF2, SREBP2
Domain
Architecture
Description Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).
TAL2_HUMAN
 
θ value θ > 10 (rank : 158) NC score 0.050996 (rank : 119)
Query Neighborhood Hits 100 Target Neighborhood Hits 77 Shared Neighborhood Hits 16
SwissProt Accessions Q16559 Gene names TAL2
Domain
Architecture
Description T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).
TAL2_MOUSE
 
θ value θ > 10 (rank : 159) NC score 0.058048 (rank : 106)
Query Neighborhood Hits 100 Target Neighborhood Hits 79 Shared Neighborhood Hits 19
SwissProt Accessions Q62282 Gene names Tal2
Domain
Architecture
Description T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).
TWST1_HUMAN
 
θ value θ > 10 (rank : 160) NC score 0.064722 (rank : 91)
Query Neighborhood Hits 100 Target Neighborhood Hits 93 Shared Neighborhood Hits 24
SwissProt Accessions Q15672, Q92487, Q99804 Gene names TWIST1, TWIST
Domain
Architecture
Description Twist-related protein 1 (H-twist).
TWST1_MOUSE
 
θ value θ > 10 (rank : 161) NC score 0.064645 (rank : 92)
Query Neighborhood Hits 100 Target Neighborhood Hits 101 Shared Neighborhood Hits 24
SwissProt Accessions P26687 Gene names Twist1, Twist
Domain
Architecture
Description Twist-related protein 1 (M-twist).
TWST2_HUMAN
 
θ value θ > 10 (rank : 162) NC score 0.063723 (rank : 96)
Query Neighborhood Hits 100 Target Neighborhood Hits 107 Shared Neighborhood Hits 24
SwissProt Accessions Q8WVJ9 Gene names TWIST2, DERMO1
Domain
Architecture
Description Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).
TWST2_MOUSE
 
θ value θ > 10 (rank : 163) NC score 0.063821 (rank : 95)
Query Neighborhood Hits 100 Target Neighborhood Hits 107 Shared Neighborhood Hits 24
SwissProt Accessions Q9D030 Gene names Twist2, Dermo1
Domain
Architecture
Description Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

Hits sorted by NC score


MLX_MOUSE
 
NC score 0.999962 (rank : 1) θ value 9.19922e-154 (rank : 1)
Query Neighborhood Hits 100 Target Neighborhood Hits 100 Shared Neighborhood Hits 100
SwissProt Accessions O08609, Q9EQJ7, Q9EQJ8 Gene names Mlx, Tcfl4
Domain
Architecture
Description Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).
MLX_HUMAN
 
NC score 0.995677 (rank : 2) θ value 2.42647e-146 (rank : 2)
Query Neighborhood Hits 100 Target Neighborhood Hits 95 Shared Neighborhood Hits 92
SwissProt Accessions Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3 Gene names MLX, TCFL4
Domain
Architecture
Description Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).
WBS14_MOUSE
 
NC score 0.558132 (rank : 3) θ value 5.07402e-19 (rank : 3)
Query Neighborhood Hits 100 Target Neighborhood Hits 171 Shared Neighborhood Hits 16
SwissProt Accessions Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5 Gene names Mlxipl, Mio, Wbscr14
Domain
Architecture
Description Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).
WBS14_HUMAN
 
NC score 0.526280 (rank : 4) θ value 4.29542e-18 (rank : 4)
Query Neighborhood Hits 100 Target Neighborhood Hits 273 Shared Neighborhood Hits 22
SwissProt Accessions Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3 Gene names MLXIPL, MIO, WBSCR14
Domain
Architecture
Description Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).
MAX_MOUSE
 
NC score 0.471341 (rank : 5) θ value 3.77169e-06 (rank : 6)
Query Neighborhood Hits 100 Target Neighborhood Hits 139 Shared Neighborhood Hits 46
SwissProt Accessions P28574 Gene names Max, Myn
Domain
Architecture
Description Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).
MAX_HUMAN
 
NC score 0.461639 (rank : 6) θ value 1.43324e-05 (rank : 10)
Query Neighborhood Hits 100 Target Neighborhood Hits 125 Shared Neighborhood Hits 45
SwissProt Accessions P61244, P25912, P52163 Gene names MAX
Domain
Architecture
Description Protein max (Myc-associated factor X).
USF1_MOUSE
 
NC score 0.432604 (rank : 7) θ value 6.43352e-06 (rank : 8)
Query Neighborhood Hits 100 Target Neighborhood Hits 71 Shared Neighborhood Hits 41
SwissProt Accessions Q61069 Gene names Usf1, Usf
Domain
Architecture
Description Upstream stimulatory factor 1 (Major late transcription factor 1).
USF1_HUMAN
 
NC score 0.432230 (rank : 8) θ value 6.43352e-06 (rank : 7)
Query Neighborhood Hits 100 Target Neighborhood Hits 70 Shared Neighborhood Hits 41
SwissProt Accessions P22415 Gene names USF1, USF
Domain
Architecture
Description Upstream stimulatory factor 1 (Major late transcription factor 1).
USF2_MOUSE
 
NC score 0.425036 (rank : 9) θ value 0.000121331 (rank : 13)
Query Neighborhood Hits 100 Target Neighborhood Hits 173 Shared Neighborhood Hits 47
SwissProt Accessions Q64705, Q3UIL2, Q8VE59 Gene names Usf2
Domain
Architecture
Description Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).
USF2_HUMAN
 
NC score 0.421414 (rank : 10) θ value 0.000121331 (rank : 12)
Query Neighborhood Hits 100 Target Neighborhood Hits 155 Shared Neighborhood Hits 47
SwissProt Accessions Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852 Gene names USF2
Domain
Architecture
Description Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).
HEY1_HUMAN
 
NC score 0.360723 (rank : 11) θ value 2.21117e-06 (rank : 5)
Query Neighborhood Hits 100 Target Neighborhood Hits 82 Shared Neighborhood Hits 38
SwissProt Accessions Q9Y5J3, Q5TZS3, Q9NYP4 Gene names HEY1, CHF2, HESR1
Domain
Architecture
Description Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).
HEY1_MOUSE
 
NC score 0.358160 (rank : 12) θ value 8.40245e-06 (rank : 9)
Query Neighborhood Hits 100 Target Neighborhood Hits 69 Shared Neighborhood Hits 38
SwissProt Accessions Q9WV93 Gene names Hey1, Hesr1
Domain
Architecture
Description Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).
TFAP4_HUMAN
 
NC score 0.351072 (rank : 13) θ value 9.29e-05 (rank : 11)
Query Neighborhood Hits 100 Target Neighborhood Hits 289 Shared Neighborhood Hits 44
SwissProt Accessions Q01664, O60409 Gene names TFAP4
Domain
Architecture
Description Transcription factor AP-4 (Activating enhancer-binding protein 4).
TFE3_HUMAN
 
NC score 0.325189 (rank : 14) θ value 0.00390308 (rank : 23)
Query Neighborhood Hits 100 Target Neighborhood Hits 190 Shared Neighborhood Hits 52
SwissProt Accessions P19532, Q92757, Q92758, Q99964 Gene names TFE3
Domain
Architecture
Description Transcription factor E3.
HEY2_HUMAN
 
NC score 0.321065 (rank : 15) θ value 0.00102713 (rank : 18)
Query Neighborhood Hits 100 Target Neighborhood Hits 77 Shared Neighborhood Hits 38
SwissProt Accessions Q9UBP5 Gene names HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain
Architecture

No domain graphic available

Description Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).
HEY2_MOUSE
 
NC score 0.320280 (rank : 16) θ value 0.00134147 (rank : 19)
Query Neighborhood Hits 100 Target Neighborhood Hits 80 Shared Neighborhood Hits 38
SwissProt Accessions Q9QUS4, Q3TZ99, Q8CD44 Gene names Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain
Architecture

No domain graphic available

Description Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).
MYC_MOUSE
 
NC score 0.289930 (rank : 17) θ value 0.00509761 (rank : 24)
Query Neighborhood Hits 100 Target Neighborhood Hits 125 Shared Neighborhood Hits 35
SwissProt Accessions P01108, P70247, Q3UM70, Q61422 Gene names Myc
Domain
Architecture
Description Myc proto-oncogene protein (c-Myc) (Transcription factor p64).
SRBP1_HUMAN
 
NC score 0.289732 (rank : 18) θ value 0.000786445 (rank : 16)
Query Neighborhood Hits 100 Target Neighborhood Hits 225 Shared Neighborhood Hits 46
SwissProt Accessions P36956, Q16062 Gene names SREBF1, SREBP1
Domain
Architecture
Description Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).
MYC_HUMAN
 
NC score 0.289489 (rank : 19) θ value 0.00390308 (rank : 22)
Query Neighborhood Hits 100 Target Neighborhood Hits 146 Shared Neighborhood Hits 39
SwissProt Accessions P01106, P01107, Q14026 Gene names MYC
Domain
Architecture
Description Myc proto-oncogene protein (c-Myc) (Transcription factor p64).
MYCS_MOUSE
 
NC score 0.286660 (rank : 20) θ value 0.00390308 (rank : 21)
Query Neighborhood Hits 100 Target Neighborhood Hits 83 Shared Neighborhood Hits 35
SwissProt Accessions Q9Z304 Gene names Mycs
Domain
Architecture
Description Protein S-myc.
SRBP1_MOUSE
 
NC score 0.284117 (rank : 21) θ value 0.000461057 (rank : 15)
Query Neighborhood Hits 100 Target Neighborhood Hits 384 Shared Neighborhood Hits 50
SwissProt Accessions Q9WTN3 Gene names Srebf1, Srebp1
Domain
Architecture
Description Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).
MITF_HUMAN
 
NC score 0.280055 (rank : 22) θ value 0.163984 (rank : 35)
Query Neighborhood Hits 100 Target Neighborhood Hits 113 Shared Neighborhood Hits 48
SwissProt Accessions O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8 Gene names MITF
Domain
Architecture
Description Microphthalmia-associated transcription factor.
MITF_MOUSE
 
NC score 0.274097 (rank : 23) θ value 0.365318 (rank : 42)
Query Neighborhood Hits 100 Target Neighborhood Hits 115 Shared Neighborhood Hits 49
SwissProt Accessions Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9 Gene names Mitf, Bw, Mi, Vit
Domain
Architecture
Description Microphthalmia-associated transcription factor.
MYCN_HUMAN
 
NC score 0.270075 (rank : 24) θ value 0.125558 (rank : 33)
Query Neighborhood Hits 100 Target Neighborhood Hits 127 Shared Neighborhood Hits 35
SwissProt Accessions P04198, Q6LDT9 Gene names MYCN, NMYC
Domain
Architecture
Description N-myc proto-oncogene protein.
MYCN_MOUSE
 
NC score 0.255636 (rank : 25) θ value 0.0961366 (rank : 32)
Query Neighborhood Hits 100 Target Neighborhood Hits 125 Shared Neighborhood Hits 36
SwissProt Accessions P03966, Q61978 Gene names Mycn, Nmyc, Nmyc1
Domain
Architecture
Description N-myc proto-oncogene protein.
TFEB_MOUSE
 
NC score 0.241411 (rank : 26) θ value 0.21417 (rank : 38)
Query Neighborhood Hits 100 Target Neighborhood Hits 119 Shared Neighborhood Hits 43
SwissProt Accessions Q9R210 Gene names Tfeb, Tcfeb
Domain
Architecture
Description Transcription factor EB.
TFEB_HUMAN
 
NC score 0.237695 (rank : 27) θ value 0.47712 (rank : 49)
Query Neighborhood Hits 100 Target Neighborhood Hits 111 Shared Neighborhood Hits 43
SwissProt Accessions P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8 Gene names TFEB
Domain
Architecture
Description Transcription factor EB.
MYCL1_MOUSE
 
NC score 0.235145 (rank : 28) θ value 0.0961366 (rank : 31)
Query Neighborhood Hits 100 Target Neighborhood Hits 123 Shared Neighborhood Hits 39
SwissProt Accessions P10166, Q5FWI7 Gene names Mycl1, Lmyc1, Mycl
Domain
Architecture
Description L-myc-1 proto-oncogene protein.
MYCL1_HUMAN
 
NC score 0.232636 (rank : 29) θ value 0.21417 (rank : 37)
Query Neighborhood Hits 100 Target Neighborhood Hits 146 Shared Neighborhood Hits 40
SwissProt Accessions P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9 Gene names MYCL1, LMYC, MYCL
Domain
Architecture
Description L-myc-1 proto-oncogene protein.
BMAL1_HUMAN
 
NC score 0.224782 (rank : 30) θ value 0.000461057 (rank : 14)
Query Neighborhood Hits 100 Target Neighborhood Hits 115 Shared Neighborhood Hits 43
SwissProt Accessions O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649 Gene names ARNTL, BMAL1, MOP3
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).
BMAL1_MOUSE
 
NC score 0.223472 (rank : 31) θ value 0.00102713 (rank : 17)
Query Neighborhood Hits 100 Target Neighborhood Hits 121 Shared Neighborhood Hits 43
SwissProt Accessions Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9 Gene names Arntl, Bmal1
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).
SRBP2_HUMAN
 
NC score 0.216353 (rank : 32) θ value θ > 10 (rank : 157)
Query Neighborhood Hits 100 Target Neighborhood Hits 133 Shared Neighborhood Hits 41
SwissProt Accessions Q12772, Q9UH04 Gene names SREBF2, SREBP2
Domain
Architecture
Description Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).
BHLH3_HUMAN
 
NC score 0.205543 (rank : 33) θ value 0.279714 (rank : 39)
Query Neighborhood Hits 100 Target Neighborhood Hits 106 Shared Neighborhood Hits 34
SwissProt Accessions Q9C0J9 Gene names BHLHB3, DEC2, SHARP1
Domain
Architecture
Description Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).
BHLH3_MOUSE
 
NC score 0.204986 (rank : 34) θ value 0.279714 (rank : 40)
Query Neighborhood Hits 100 Target Neighborhood Hits 70 Shared Neighborhood Hits 34
SwissProt Accessions Q99PV5 Gene names Bhlhb3, Dec2
Domain
Architecture
Description Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).
TCFL5_HUMAN
 
NC score 0.204771 (rank : 35) θ value 0.0563607 (rank : 28)
Query Neighborhood Hits 100 Target Neighborhood Hits 43 Shared Neighborhood Hits 24
SwissProt Accessions Q9UL49, O94771, Q9BYW0 Gene names TCFL5, CHA, E2BP1
Domain
Architecture

No domain graphic available

Description Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).
CLOCK_MOUSE
 
NC score 0.196144 (rank : 36) θ value 0.00390308 (rank : 20)
Query Neighborhood Hits 100 Target Neighborhood Hits 148 Shared Neighborhood Hits 38
SwissProt Accessions O08785 Gene names Clock
Domain
Architecture
Description Circadian locomoter output cycles protein kaput (mCLOCK).
CLOCK_HUMAN
 
NC score 0.192989 (rank : 37) θ value 0.00665767 (rank : 25)
Query Neighborhood Hits 100 Target Neighborhood Hits 127 Shared Neighborhood Hits 36
SwissProt Accessions O15516, O14516, Q9UIT8 Gene names CLOCK, KIAA0334
Domain
Architecture
Description Circadian locomoter output cycles protein kaput (hCLOCK).
BHLH2_HUMAN
 
NC score 0.185586 (rank : 38) θ value 0.47712 (rank : 47)
Query Neighborhood Hits 100 Target Neighborhood Hits 80 Shared Neighborhood Hits 36
SwissProt Accessions O14503, Q96TD3 Gene names BHLHB2, DEC1, SHARP2, STRA13
Domain
Architecture
Description Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).
BHLH2_MOUSE
 
NC score 0.176044 (rank : 39) θ value 0.813845 (rank : 53)
Query Neighborhood Hits 100 Target Neighborhood Hits 70 Shared Neighborhood Hits 32
SwissProt Accessions O35185, P97289 Gene names Bhlhb2, Clast5, Stra13
Domain
Architecture
Description Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).
ARNT_HUMAN
 
NC score 0.168694 (rank : 40) θ value 5.27518 (rank : 81)
Query Neighborhood Hits 100 Target Neighborhood Hits 109 Shared Neighborhood Hits 43
SwissProt Accessions P27540 Gene names ARNT
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).
MYCL2_HUMAN
 
NC score 0.166920 (rank : 41) θ value θ > 10 (rank : 139)
Query Neighborhood Hits 100 Target Neighborhood Hits 63 Shared Neighborhood Hits 22
SwissProt Accessions P12525 Gene names MYCL2
Domain
Architecture
Description L-myc-2 protein.
ARNT_MOUSE
 
NC score 0.166800 (rank : 42) θ value 5.27518 (rank : 82)
Query Neighborhood Hits 100 Target Neighborhood Hits 213 Shared Neighborhood Hits 44
SwissProt Accessions P53762, Q60661 Gene names Arnt
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).
ARNT2_MOUSE
 
NC score 0.161243 (rank : 43) θ value 5.27518 (rank : 80)
Query Neighborhood Hits 100 Target Neighborhood Hits 115 Shared Neighborhood Hits 43
SwissProt Accessions Q61324 Gene names Arnt2
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).
ARNT2_HUMAN
 
NC score 0.160457 (rank : 44) θ value 5.27518 (rank : 79)
Query Neighborhood Hits 100 Target Neighborhood Hits 109 Shared Neighborhood Hits 43
SwissProt Accessions Q9HBZ2, O15024 Gene names ARNT2, KIAA0307
Domain
Architecture
Description Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).
NPAS2_HUMAN
 
NC score 0.159794 (rank : 45) θ value 0.365318 (rank : 44)
Query Neighborhood Hits 100 Target Neighborhood Hits 150 Shared Neighborhood Hits 32
SwissProt Accessions Q99743, Q99629 Gene names NPAS2
Domain
Architecture
Description Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).
NPAS2_MOUSE
 
NC score 0.159039 (rank : 46) θ value 0.365318 (rank : 45)
Query Neighborhood Hits 100 Target Neighborhood Hits 132 Shared Neighborhood Hits 32
SwissProt Accessions P97460 Gene names Npas2
Domain
Architecture
Description Neuronal PAS domain-containing protein 2 (Neuronal PAS2).
FIGLA_HUMAN
 
NC score 0.147954 (rank : 47) θ value 0.365318 (rank : 41)
Query Neighborhood Hits 100 Target Neighborhood Hits 108 Shared Neighborhood Hits 26
SwissProt Accessions Q6QHK4 Gene names FIGLA
Domain
Architecture

No domain graphic available

Description Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).
FIGLA_MOUSE
 
NC score 0.146946 (rank : 48) θ value 0.813845 (rank : 54)
Query Neighborhood Hits 100 Target Neighborhood Hits 100 Shared Neighborhood Hits 26
SwissProt Accessions O55208 Gene names Figla
Domain
Architecture

No domain graphic available

Description Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).
HEN2_HUMAN
 
NC score 0.135634 (rank : 49) θ value 0.0563607 (rank : 27)
Query Neighborhood Hits 100 Target Neighborhood Hits 83 Shared Neighborhood Hits 20
SwissProt Accessions Q02577 Gene names NHLH2, HEN2
Domain
Architecture
Description Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).
HES4_HUMAN
 
NC score 0.135424 (rank : 50) θ value θ > 10 (rank : 119)
Query Neighborhood Hits 100 Target Neighborhood Hits 58 Shared Neighborhood Hits 31
SwissProt Accessions Q9HCC6 Gene names HES4
Domain
Architecture
Description Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).
HEN2_MOUSE
 
NC score 0.133771 (rank : 51) θ value 0.0736092 (rank : 29)
Query Neighborhood Hits 100 Target Neighborhood Hits 83 Shared Neighborhood Hits 20
SwissProt Accessions Q64221 Gene names Nhlh2, Hen2
Domain
Architecture
Description Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).
HES1_MOUSE
 
NC score 0.129535 (rank : 52) θ value θ > 10 (rank : 115)
Query Neighborhood Hits 100 Target Neighborhood Hits 78 Shared Neighborhood Hits 26
SwissProt Accessions P35428 Gene names Hes1, Hes-1
Domain
Architecture
Description Transcription factor HES-1 (Hairy and enhancer of split 1).
HES1_HUMAN
 
NC score 0.129233 (rank : 53) θ value θ > 10 (rank : 114)
Query Neighborhood Hits 100 Target Neighborhood Hits 76 Shared Neighborhood Hits 26
SwissProt Accessions Q14469 Gene names HES1, HL, HRY
Domain
Architecture
Description Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).
HEN1_MOUSE
 
NC score 0.124480 (rank : 54) θ value 0.21417 (rank : 36)
Query Neighborhood Hits 100 Target Neighborhood Hits 86 Shared Neighborhood Hits 20
SwissProt Accessions Q02576 Gene names Nhlh1, Hen1
Domain
Architecture
Description Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).
HES5_MOUSE
 
NC score 0.123772 (rank : 55) θ value θ > 10 (rank : 120)
Query Neighborhood Hits 100 Target Neighborhood Hits 38 Shared Neighborhood Hits 17
SwissProt Accessions P70120, Q8BVI1 Gene names Hes5, Hes-5
Domain
Architecture
Description Transcription factor HES-5 (Hairy and enhancer of split 5).
MYCB_MOUSE
 
NC score 0.116107 (rank : 56) θ value θ > 10 (rank : 138)
Query Neighborhood Hits 100 Target Neighborhood Hits 14 Shared Neighborhood Hits 7
SwissProt Accessions Q6P8Z1, Q9D6E3 Gene names Mycb, Bmyc
Domain
Architecture

No domain graphic available

Description Protein B-Myc.
TAL1_HUMAN
 
NC score 0.113339 (rank : 57) θ value 0.62314 (rank : 51)
Query Neighborhood Hits 100 Target Neighborhood Hits 112 Shared Neighborhood Hits 29
SwissProt Accessions P17542 Gene names TAL1, SCL, TCL5
Domain
Architecture
Description T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).
TAL1_MOUSE
 
NC score 0.112166 (rank : 58) θ value 0.62314 (rank : 52)
Query Neighborhood Hits 100 Target Neighborhood Hits 110 Shared Neighborhood Hits 29
SwissProt Accessions P22091 Gene names Tal1, Scl, Tal-1
Domain
Architecture
Description T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).
MNT_HUMAN
 
NC score 0.105122 (rank : 59) θ value θ > 10 (rank : 134)
Query Neighborhood Hits 100 Target Neighborhood Hits 496 Shared Neighborhood Hits 37
SwissProt Accessions Q99583 Gene names MNT, ROX
Domain
Architecture
Description Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).
MNT_MOUSE
 
NC score 0.103313 (rank : 60) θ value θ > 10 (rank : 135)
Query Neighborhood Hits 100 Target Neighborhood Hits 432 Shared Neighborhood Hits 38
SwissProt Accessions O08789, P97349 Gene names Mnt, Rox
Domain
Architecture
Description Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).
HEN1_HUMAN
 
NC score 0.095645 (rank : 61) θ value 3.0926 (rank : 70)
Query Neighborhood Hits 100 Target Neighborhood Hits 88 Shared Neighborhood Hits 20
SwissProt Accessions Q02575 Gene names NHLH1, HEN1
Domain
Architecture
Description Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).
NCOA1_HUMAN
 
NC score 0.093251 (rank : 62) θ value 1.81305 (rank : 62)
Query Neighborhood Hits 100 Target Neighborhood Hits 198 Shared Neighborhood Hits 26
SwissProt Accessions Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3 Gene names NCOA1, SRC1
Domain
Architecture

No domain graphic available

Description Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).
NCOA1_MOUSE
 
NC score 0.093059 (rank : 63) θ value 1.81305 (rank : 63)
Query Neighborhood Hits 100 Target Neighborhood Hits 196 Shared Neighborhood Hits 24
SwissProt Accessions P70365, P70366, Q61202, Q8CBI9 Gene names Ncoa1, Src1
Domain
Architecture

No domain graphic available

Description Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).
ID1_MOUSE
 
NC score 0.092156 (rank : 64) θ value 2.36792 (rank : 67)
Query Neighborhood Hits 100 Target Neighborhood Hits 64 Shared Neighborhood Hits 20
SwissProt Accessions P20067, Q61101, Q9D897 Gene names Id1, Id, Id-1, Idb1
Domain
Architecture
Description DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).
MXI1_MOUSE
 
NC score 0.091477 (rank : 65) θ value θ > 10 (rank : 137)
Query Neighborhood Hits 100 Target Neighborhood Hits 109 Shared Neighborhood Hits 29
SwissProt Accessions P50540 Gene names Mxi1
Domain
Architecture
Description MAX-interacting protein 1 (Protein MXI1).
HES6_HUMAN
 
NC score 0.089538 (rank : 66) θ value θ > 10 (rank : 121)
Query Neighborhood Hits 100 Target Neighborhood Hits 49 Shared Neighborhood Hits 13
SwissProt Accessions Q96HZ4, Q8N2J2, Q96T93, Q9P2S3 Gene names HES6
Domain
Architecture

No domain graphic available

Description Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).
HES2_MOUSE
 
NC score 0.089537 (rank : 67) θ value θ > 10 (rank : 117)
Query Neighborhood Hits 100 Target Neighborhood Hits 36 Shared Neighborhood Hits 12
SwissProt Accessions O54792 Gene names Hes2
Domain
Architecture
Description Transcription factor HES-2 (Hairy and enhancer of split 2).
MAD4_HUMAN
 
NC score 0.089160 (rank : 68) θ value θ > 10 (rank : 132)
Query Neighborhood Hits 100 Target Neighborhood Hits 94 Shared Neighborhood Hits 30
SwissProt Accessions Q14582, Q5TZX4 Gene names MXD4, MAD4
Domain
Architecture
Description Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).
ID1_HUMAN
 
NC score 0.089102 (rank : 69) θ value 2.36792 (rank : 66)
Query Neighborhood Hits 100 Target Neighborhood Hits 63 Shared Neighborhood Hits 20
SwissProt Accessions P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109 Gene names ID1, ID
Domain
Architecture
Description DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).
HES6_MOUSE
 
NC score 0.087281 (rank : 70) θ value θ > 10 (rank : 122)
Query Neighborhood Hits 100 Target Neighborhood Hits 49 Shared Neighborhood Hits 12
SwissProt Accessions Q9JHE6, Q3U2D7 Gene names Hes6
Domain
Architecture

No domain graphic available

Description Transcription cofactor HES-6 (Hairy and enhancer of split 6).
MXI1_HUMAN
 
NC score 0.087053 (rank : 71) θ value θ > 10 (rank : 136)
Query Neighborhood Hits 100 Target Neighborhood Hits 76 Shared Neighborhood Hits 28
SwissProt Accessions P50539, Q15887 Gene names MXI1
Domain
Architecture
Description MAX-interacting protein 1 (Protein MXI1).
HES2_HUMAN
 
NC score 0.084665 (rank : 72) θ value θ > 10 (rank : 116)
Query Neighborhood Hits 100 Target Neighborhood Hits 38 Shared Neighborhood Hits 10
SwissProt Accessions Q9Y543, Q96EN4, Q9Y542 Gene names HES2
Domain
Architecture
Description Transcription factor HES-2 (Hairy and enhancer of split 2).
HES3_MOUSE
 
NC score 0.081597 (rank : 73) θ value θ > 10 (rank : 118)
Query Neighborhood Hits 100 Target Neighborhood Hits 38 Shared Neighborhood Hits 14
SwissProt Accessions Q61657, O09083, O09150 Gene names Hes3, Hes-3
Domain
Architecture
Description Transcription factor HES-3 (Hairy and enhancer of split 3).
BHLH8_MOUSE
 
NC score 0.080931 (rank : 74) θ value θ > 10 (rank : 107)
Query Neighborhood Hits 100 Target Neighborhood Hits 107 Shared Neighborhood Hits 32
SwissProt Accessions Q9QYC3, Q9QYE4 Gene names Bhlhb8, Mist1
Domain
Architecture

No domain graphic available

Description Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).
BHLH8_HUMAN
 
NC score 0.080252 (rank : 75) θ value θ > 10 (rank : 106)
Query Neighborhood Hits 100 Target Neighborhood Hits 123 Shared Neighborhood Hits 32
SwissProt Accessions Q7RTS1 Gene names BHLHB8, MIST1
Domain
Architecture

No domain graphic available

Description Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).
MAD3_HUMAN
 
NC score 0.080152 (rank : 76) θ value θ > 10 (rank : 130)
Query Neighborhood Hits 100 Target Neighborhood Hits 92 Shared Neighborhood Hits 31
SwissProt Accessions Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3 Gene names MXD3, MAD3
Domain
Architecture

No domain graphic available

Description Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).
HES7_HUMAN
 
NC score 0.077041 (rank : 77) θ value θ > 10 (rank : 123)
Query Neighborhood Hits 100 Target Neighborhood Hits 72 Shared Neighborhood Hits 20
SwissProt Accessions Q9BYE0 Gene names HES7
Domain
Architecture

No domain graphic available

Description Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).
HES7_MOUSE
 
NC score 0.076462 (rank : 78) θ value θ > 10 (rank : 124)
Query Neighborhood Hits 100 Target Neighborhood Hits 72 Shared Neighborhood Hits 19
SwissProt Accessions Q8BKT2, Q99JA6 Gene names Hes7
Domain
Architecture

No domain graphic available

Description Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).
MAD3_MOUSE
 
NC score 0.074460 (rank : 79) θ value θ > 10 (rank : 131)
Query Neighborhood Hits 100 Target Neighborhood Hits 94 Shared Neighborhood Hits 29
SwissProt Accessions Q80US8, Q60947 Gene names Mxd3, Mad3
Domain
Architecture

No domain graphic available

Description Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).
HAND2_HUMAN
 
NC score 0.074297 (rank : 80) θ value θ > 10 (rank : 112)
Query Neighborhood Hits 100 Target Neighborhood Hits 99 Shared Neighborhood Hits 28
SwissProt Accessions P61296, O95300, O95301, P97833 Gene names HAND2, DHAND
Domain
Architecture
Description Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).
HAND2_MOUSE
 
NC score 0.074297 (rank : 81) θ value θ > 10 (rank : 113)
Query Neighborhood Hits 100 Target Neighborhood Hits 99 Shared Neighborhood Hits 28
SwissProt Accessions Q61039, Q61100 Gene names Hand2, Dhand, Hed, Thing2
Domain
Architecture
Description Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).
HAND1_HUMAN
 
NC score 0.068336 (rank : 82) θ value θ > 10 (rank : 110)
Query Neighborhood Hits 100 Target Neighborhood Hits 100 Shared Neighborhood Hits 31
SwissProt Accessions O96004 Gene names HAND1, EHAND
Domain
Architecture
Description Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).
EPAS1_HUMAN
 
NC score 0.067571 (rank : 83) θ value θ > 10 (rank : 108)
Query Neighborhood Hits 100 Target Neighborhood Hits 76 Shared Neighborhood Hits 13
SwissProt Accessions Q99814, Q86VA2, Q99630 Gene names EPAS1, HIF2A
Domain
Architecture
Description Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).
AHR_HUMAN
 
NC score 0.066840 (rank : 84) θ value θ > 10 (rank : 101)
Query Neighborhood Hits 100 Target Neighborhood Hits 47 Shared Neighborhood Hits 14
SwissProt Accessions P35869, Q13728, Q13803, Q13804 Gene names AHR
Domain
Architecture
Description Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).
EPAS1_MOUSE
 
NC score 0.066095 (rank : 85) θ value θ > 10 (rank : 109)
Query Neighborhood Hits 100 Target Neighborhood Hits 94 Shared Neighborhood Hits 12
SwissProt Accessions P97481, O08787, O55046 Gene names Epas1, Hif2a
Domain
Architecture
Description Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).
HIF1A_HUMAN
 
NC score 0.065831 (rank : 86) θ value θ > 10 (rank : 125)
Query Neighborhood Hits 100 Target Neighborhood Hits 118 Shared Neighborhood Hits 12
SwissProt Accessions Q16665, Q96PT9, Q9UPB1 Gene names HIF1A
Domain
Architecture
Description Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).
HAND1_MOUSE
 
NC score 0.065468 (rank : 87) θ value θ > 10 (rank : 111)
Query Neighborhood Hits 100 Target Neighborhood Hits 107 Shared Neighborhood Hits 33
SwissProt Accessions Q64279, Q61099 Gene names Hand1, Ehand, Hxt, Thing1
Domain
Architecture
Description Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).
AHR_MOUSE
 
NC score 0.065402 (rank : 88) θ value θ > 10 (rank : 102)
Query Neighborhood Hits 100 Target Neighborhood Hits 55 Shared Neighborhood Hits 12
SwissProt Accessions P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1 Gene names Ahr
Domain
Architecture
Description Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).
HIF1A_MOUSE
 
NC score 0.065290 (rank : 89) θ value θ > 10 (rank : 126)
Query Neighborhood Hits 100 Target Neighborhood Hits 90 Shared Neighborhood Hits 12
SwissProt Accessions Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8 Gene names Hif1a
Domain
Architecture
Description Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).
SIM2_HUMAN
 
NC score 0.064860 (rank : 90) θ value θ > 10 (rank : 155)
Query Neighborhood Hits 100 Target Neighborhood Hits 76 Shared Neighborhood Hits 16
SwissProt Accessions Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532 Gene names SIM2
Domain
Architecture
Description Single-minded homolog 2.
TWST1_HUMAN
 
NC score 0.064722 (rank : 91) θ value θ > 10 (rank : 160)
Query Neighborhood Hits 100 Target Neighborhood Hits 93 Shared Neighborhood Hits 24
SwissProt Accessions Q15672, Q92487, Q99804 Gene names TWIST1, TWIST
Domain
Architecture
Description Twist-related protein 1 (H-twist).
TWST1_MOUSE
 
NC score 0.064645 (rank : 92) θ value θ > 10 (rank : 161)
Query Neighborhood Hits 100 Target Neighborhood Hits 101 Shared Neighborhood Hits 24
SwissProt Accessions P26687 Gene names Twist1, Twist
Domain
Architecture
Description Twist-related protein 1 (M-twist).
SIM2_MOUSE
 
NC score 0.064308 (rank : 93) θ value θ > 10 (rank : 156)
Query Neighborhood Hits 100 Target Neighborhood Hits 75 Shared Neighborhood Hits 17
SwissProt Accessions Q61079, O35391, Q61046, Q61904 Gene names Sim2
Domain
Architecture
Description Single-minded homolog 2 (SIM transcription factor) (mSIM).
SIM1_MOUSE
 
NC score 0.063902 (rank : 94) θ value θ > 10 (rank : 154)
Query Neighborhood Hits 100 Target Neighborhood Hits 69 Shared Neighborhood Hits 16
SwissProt Accessions Q61045, O70284, P70183 Gene names Sim1
Domain
Architecture
Description Single-minded homolog 1 (mSIM1).
TWST2_MOUSE
 
NC score 0.063821 (rank : 95) θ value θ > 10 (rank : 163)
Query Neighborhood Hits 100 Target Neighborhood Hits 107 Shared Neighborhood Hits 24
SwissProt Accessions Q9D030 Gene names Twist2, Dermo1
Domain
Architecture
Description Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).
TWST2_HUMAN
 
NC score 0.063723 (rank : 96) θ value θ > 10 (rank : 162)
Query Neighborhood Hits 100 Target Neighborhood Hits 107 Shared Neighborhood Hits 24
SwissProt Accessions Q8WVJ9 Gene names TWIST2, DERMO1
Domain
Architecture
Description Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).
SIM1_HUMAN
 
NC score 0.063645 (rank : 97) θ value θ > 10 (rank : 153)
Query Neighborhood Hits 100 Target Neighborhood Hits 62 Shared Neighborhood Hits 16
SwissProt Accessions P81133, Q5TDP7 Gene names SIM1
Domain
Architecture
Description Single-minded homolog 1.
MAD1_MOUSE
 
NC score 0.063529 (rank : 98) θ value θ > 10 (rank : 129)
Query Neighborhood Hits 100 Target Neighborhood Hits 75 Shared Neighborhood Hits 26
SwissProt Accessions P50538, Q60798, Q61825 Gene names Mxd1, Mad, Mad1
Domain
Architecture
Description MAD protein (MAX dimerizer) (MAX dimerization protein 1).
PTF1A_HUMAN
 
NC score 0.063103 (rank : 99) θ value θ > 10 (rank : 150)
Query Neighborhood Hits 100 Target Neighborhood Hits 95 Shared Neighborhood Hits 26
SwissProt Accessions Q7RTS3, Q9HC25 Gene names PTF1A, PTF1P48
Domain
Architecture

No domain graphic available

Description Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).
LYL1_HUMAN
 
NC score 0.061719 (rank : 100) θ value θ > 10 (rank : 127)
Query Neighborhood Hits 100 Target Neighborhood Hits 113 Shared Neighborhood Hits 22
SwissProt Accessions P12980, O76102 Gene names LYL1
Domain
Architecture
Description Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).
PTF1A_MOUSE
 
NC score 0.061716 (rank : 101) θ value θ > 10 (rank : 151)
Query Neighborhood Hits 100 Target Neighborhood Hits 100 Shared Neighborhood Hits 28
SwissProt Accessions Q9QX98, Q9QYF5, Q9QYF6 Gene names Ptf1a, Ptf1p48
Domain
Architecture

No domain graphic available

Description Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).
NCOA3_HUMAN
 
NC score 0.060957 (rank : 102) θ value θ > 10 (rank : 142)
Query Neighborhood Hits 100 Target Neighborhood Hits 171 Shared Neighborhood Hits 13
SwissProt Accessions Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7 Gene names NCOA3, AIB1, RAC3, TRAM1
Domain
Architecture
Description Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).
NPAS3_MOUSE
 
NC score 0.059552 (rank : 103) θ value θ > 10 (rank : 147)
Query Neighborhood Hits 100 Target Neighborhood Hits 103 Shared Neighborhood Hits 17
SwissProt Accessions Q9QZQ0, Q9EQP4 Gene names Npas3
Domain
Architecture
Description Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).
LYL1_MOUSE
 
NC score 0.059426 (rank : 104) θ value θ > 10 (rank : 128)
Query Neighborhood Hits 100 Target Neighborhood Hits 102 Shared Neighborhood Hits 20
SwissProt Accessions P27792 Gene names Lyl1, Lyl-1
Domain
Architecture
Description Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).
NPAS3_HUMAN
 
NC score 0.058502 (rank : 105) θ value θ > 10 (rank : 146)
Query Neighborhood Hits 100 Target Neighborhood Hits 81 Shared Neighborhood Hits 16
SwissProt Accessions Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8 Gene names NPAS3
Domain
Architecture
Description Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).
TAL2_MOUSE
 
NC score 0.058048 (rank : 106) θ value θ > 10 (rank : 159)
Query Neighborhood Hits 100 Target Neighborhood Hits 79 Shared Neighborhood Hits 19
SwissProt Accessions Q62282 Gene names Tal2
Domain
Architecture
Description T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).
PHAR2_HUMAN
 
NC score 0.057834 (rank : 107) θ value 0.365318 (rank : 46)
Query Neighborhood Hits 100 Target Neighborhood Hits 208 Shared Neighborhood Hits 3
SwissProt Accessions O75167, Q68DM2 Gene names PHACTR2, C6orf56, KIAA0680
Domain
Architecture

No domain graphic available

Description Phosphatase and actin regulator 2.
NCOA2_MOUSE
 
NC score 0.056864 (rank : 108) θ value θ > 10 (rank : 141)
Query Neighborhood Hits 100 Target Neighborhood Hits 281 Shared Neighborhood Hits 13
SwissProt Accessions Q61026, O09001, P97759 Gene names Ncoa2, Grip1, Tif2
Domain
Architecture
Description Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).
NCOA2_HUMAN
 
NC score 0.056464 (rank : 109) θ value θ > 10 (rank : 140)
Query Neighborhood Hits 100 Target Neighborhood Hits 281 Shared Neighborhood Hits 12
SwissProt Accessions Q15596 Gene names NCOA2, TIF2
Domain
Architecture
Description Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).
NPAS1_MOUSE
 
NC score 0.055194 (rank : 110) θ value θ > 10 (rank : 145)
Query Neighborhood Hits 100 Target Neighborhood Hits 63 Shared Neighborhood Hits 15
SwissProt Accessions P97459 Gene names Npas1
Domain
Architecture
Description Neuronal PAS domain-containing protein 1 (Neuronal PAS1).
NCOA3_MOUSE
 
NC score 0.054624 (rank : 111) θ value θ > 10 (rank : 143)
Query Neighborhood Hits 100 Target Neighborhood Hits 203 Shared Neighborhood Hits 13
SwissProt Accessions O09000, Q9CRD5 Gene names Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain
Architecture
Description Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).
ASCL1_HUMAN
 
NC score 0.053840 (rank : 112) θ value θ > 10 (rank : 103)
Query Neighborhood Hits 100 Target Neighborhood Hits 94 Shared Neighborhood Hits 22
SwissProt Accessions P50553, Q9BQ30 Gene names ASCL1, ASH1
Domain
Architecture
Description Achaete-scute homolog 1 (HASH1).
MYF5_HUMAN
 
NC score 0.053839 (rank : 113) θ value 5.27518 (rank : 87)
Query Neighborhood Hits 100 Target Neighborhood Hits 80 Shared Neighborhood Hits 19
SwissProt Accessions P13349 Gene names MYF5
Domain
Architecture
Description Myogenic factor 5 (Myf-5).
MAD4_MOUSE
 
NC score 0.053711 (rank : 114) θ value θ > 10 (rank : 133)
Query Neighborhood Hits 100 Target Neighborhood Hits 65 Shared Neighborhood Hits 16
SwissProt Accessions Q60948 Gene names Mxd4, Mad4
Domain
Architecture
Description Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).
MYF5_MOUSE
 
NC score 0.053610 (rank : 115) θ value 5.27518 (rank : 88)
Query Neighborhood Hits 100 Target Neighborhood Hits 77 Shared Neighborhood Hits 19
SwissProt Accessions P24699, Q543W7 Gene names Myf5, Myf-5
Domain
Architecture
Description Myogenic factor 5 (Myf-5).
NPAS1_HUMAN
 
NC score 0.053426 (rank : 116) θ value θ > 10 (rank : 144)
Query Neighborhood Hits 100 Target Neighborhood Hits 77 Shared Neighborhood Hits 14
SwissProt Accessions Q99742, Q99632, Q9BY83 Gene names NPAS1
Domain
Architecture
Description Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).
SCX_MOUSE
 
NC score 0.052729 (rank : 117) θ value θ > 10 (rank : 152)
Query Neighborhood Hits 100 Target Neighborhood Hits 82 Shared Neighborhood Hits 19
SwissProt Accessions Q64124 Gene names Scx
Domain
Architecture
Description Basic helix-loop-helix transcription factor scleraxis.
NPAS4_HUMAN
 
NC score 0.052586 (rank : 118) θ value θ > 10 (rank : 148)
Query Neighborhood Hits 100 Target Neighborhood Hits 214 Shared Neighborhood Hits 14
SwissProt Accessions Q8IUM7, Q8N8S5, Q8N9Q9 Gene names NPAS4, NXF
Domain
Architecture

No domain graphic available

Description Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).
TAL2_HUMAN
 
NC score 0.050996 (rank : 119) θ value θ > 10 (rank : 158)
Query Neighborhood Hits 100 Target Neighborhood Hits 77 Shared Neighborhood Hits 16
SwissProt Accessions Q16559 Gene names TAL2
Domain
Architecture
Description T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).
ASCL2_MOUSE
 
NC score 0.050823 (rank : 120) θ value θ > 10 (rank : 105)
Query Neighborhood Hits 100 Target Neighborhood Hits 98 Shared Neighborhood Hits 22
SwissProt Accessions O35885, Q9WUJ7 Gene names Ascl2, Mash2
Domain
Architecture
Description Achaete-scute homolog 2 (Mash-2).
ASCL1_MOUSE
 
NC score 0.050592 (rank : 121) θ value θ > 10 (rank : 104)
Query Neighborhood Hits 100 Target Neighborhood Hits 97 Shared Neighborhood Hits 22
SwissProt Accessions Q02067 Gene names Ascl1, Ash1, Mash-1, Mash1
Domain
Architecture
Description Achaete-scute homolog 1 (Mash-1).
PER2_MOUSE
 
NC score 0.050227 (rank : 122) θ value θ > 10 (rank : 149)
Query Neighborhood Hits 100 Target Neighborhood Hits 325 Shared Neighborhood Hits 14
SwissProt Accessions O54943, O54954 Gene names Per2
Domain
Architecture
Description Period circadian protein 2 (mPER2).
ITF2_MOUSE
 
NC score 0.048880 (rank : 123) θ value 1.81305 (rank : 60)
Query Neighborhood Hits 100 Target Neighborhood Hits 154 Shared Neighborhood Hits 19
SwissProt Accessions Q60722, Q60721, Q62211, Q64072, Q80UE8 Gene names Tcf4, Itf2, Sef2
Domain
Architecture
Description Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).
NGN1_MOUSE
 
NC score 0.047019 (rank : 124) θ value 3.0926 (rank : 72)
Query Neighborhood Hits 100 Target Neighborhood Hits 87 Shared Neighborhood Hits 15
SwissProt Accessions P70660 Gene names Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain
Architecture
Description Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).
TRIPB_HUMAN
 
NC score 0.046095 (rank : 125) θ value 0.0736092 (rank : 30)
Query Neighborhood Hits 100 Target Neighborhood Hits 1587 Shared Neighborhood Hits 35
SwissProt Accessions Q15643, O14689, O15154, O95949 Gene names TRIP11, CEV14
Domain
Architecture

No domain graphic available

Description Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).
MDN1_HUMAN
 
NC score 0.045910 (rank : 126) θ value 0.62314 (rank : 50)
Query Neighborhood Hits 100 Target Neighborhood Hits 662 Shared Neighborhood Hits 11
SwissProt Accessions Q9NU22, O15019 Gene names MDN1, KIAA0301
Domain
Architecture
Description Midasin (MIDAS-containing protein).
RBBP6_MOUSE
 
NC score 0.039850 (rank : 127) θ value 1.06291 (rank : 57)
Query Neighborhood Hits 100 Target Neighborhood Hits 1014 Shared Neighborhood Hits 17
SwissProt Accessions P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399 Gene names Rbbp6, P2pr, Pact
Domain
Architecture

No domain graphic available

Description Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).
MYO10_HUMAN
 
NC score 0.036859 (rank : 128) θ value 0.0431538 (rank : 26)
Query Neighborhood Hits 100 Target Neighborhood Hits 920 Shared Neighborhood Hits 25
SwissProt Accessions Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6 Gene names MYO10
Domain
Architecture
Description Myosin-10 (Myosin X).
XLR_MOUSE
 
NC score 0.035703 (rank : 129) θ value 5.27518 (rank : 91)
Query Neighborhood Hits 100 Target Neighborhood Hits 73 Shared Neighborhood Hits 6
SwissProt Accessions P05531 Gene names Xlr
Domain
Architecture
Description X-linked lymphocyte-regulated protein PM1.
TRAK2_HUMAN
 
NC score 0.035484 (rank : 130) θ value 4.03905 (rank : 78)
Query Neighborhood Hits 100 Target Neighborhood Hits 476 Shared Neighborhood Hits 19
SwissProt Accessions O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6 Gene names TRAK2, ALS2CR3, KIAA0549
Domain
Architecture
Description Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).
HOME2_HUMAN
 
NC score 0.035324 (rank : 131) θ value 4.03905 (rank : 76)
Query Neighborhood Hits 100 Target Neighborhood Hits 532 Shared Neighborhood Hits 18
SwissProt Accessions Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7 Gene names HOMER2
Domain
Architecture
Description Homer protein homolog 2 (Homer-2) (Cupidin).
FOSL1_MOUSE
 
NC score 0.034192 (rank : 132) θ value 5.27518 (rank : 86)
Query Neighborhood Hits 100 Target Neighborhood Hits 113 Shared Neighborhood Hits 9
SwissProt Accessions P48755, O35285 Gene names Fosl1, Fra1
Domain
Architecture
Description Fos-related antigen 1 (FRA-1).
HOME2_MOUSE
 
NC score 0.033988 (rank : 133) θ value 3.0926 (rank : 71)
Query Neighborhood Hits 100 Target Neighborhood Hits 882 Shared Neighborhood Hits 26
SwissProt Accessions Q9QWW1, O89025, Q9Z0E4 Gene names Homer2, Vesl2
Domain
Architecture
Description Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).
CDC37_MOUSE
 
NC score 0.033953 (rank : 134) θ value 5.27518 (rank : 83)
Query Neighborhood Hits 100 Target Neighborhood Hits 359 Shared Neighborhood Hits 20
SwissProt Accessions Q61081, Q3TGP0 Gene names Cdc37
Domain
Architecture
Description Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).
FOSL1_HUMAN
 
NC score 0.033409 (rank : 135) θ value 5.27518 (rank : 85)
Query Neighborhood Hits 100 Target Neighborhood Hits 112 Shared Neighborhood Hits 7
SwissProt Accessions P15407 Gene names FOSL1, FRA1
Domain
Architecture
Description Fos-related antigen 1 (FRA-1).
CV019_HUMAN
 
NC score 0.033079 (rank : 136) θ value 6.88961 (rank : 94)
Query Neighborhood Hits 100 Target Neighborhood Hits 62 Shared Neighborhood Hits 4
SwissProt Accessions Q13769, O60839, Q9UPZ5 Gene names C22orf19, KIAA0983
Domain
Architecture

No domain graphic available

Description Protein C22orf19 (NF2/meningioma region protein pK1.3) (Placental protein 39.2).
EZRI_MOUSE
 
NC score 0.030947 (rank : 137) θ value 1.06291 (rank : 56)
Query Neighborhood Hits 100 Target Neighborhood Hits 693 Shared Neighborhood Hits 20
SwissProt Accessions P26040, Q80ZT8, Q9DCI1 Gene names Vil2
Domain
Architecture
Description Ezrin (p81) (Cytovillin) (Villin-2).
RB6I2_HUMAN
 
NC score 0.030389 (rank : 138) θ value 3.0926 (rank : 73)
Query Neighborhood Hits 100 Target Neighborhood Hits 1584 Shared Neighborhood Hits 31
SwissProt Accessions Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1 Gene names ERC1, ELKS, KIAA1081, RAB6IP2
Domain
Architecture

No domain graphic available

Description ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).
TULP1_MOUSE
 
NC score 0.030106 (rank : 139) θ value 2.36792 (rank : 68)
Query Neighborhood Hits 100 Target Neighborhood Hits 146 Shared Neighborhood Hits 6
SwissProt Accessions Q9Z273 Gene names Tulp1
Domain
Architecture
Description Tubby-related protein 1 (Tubby-like protein 1).
RB6I2_MOUSE
 
NC score 0.029704 (rank : 140) θ value 3.0926 (rank : 74)
Query Neighborhood Hits 100 Target Neighborhood Hits 1433 Shared Neighborhood Hits 32
SwissProt Accessions Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2 Gene names Erc1, Cast2, Kiaa1081, Rab6ip2
Domain
Architecture

No domain graphic available

Description ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).
RBCC1_HUMAN
 
NC score 0.029658 (rank : 141) θ value 1.38821 (rank : 58)
Query Neighborhood Hits 100 Target Neighborhood Hits 1023 Shared Neighborhood Hits 28
SwissProt Accessions Q8TDY2, Q8WVU9, Q92601 Gene names RB1CC1, KIAA0203, RBICC
Domain
Architecture

No domain graphic available

Description RB1-inducible coiled-coil protein 1.
MYH8_MOUSE
 
NC score 0.029613 (rank : 142) θ value 0.365318 (rank : 43)
Query Neighborhood Hits 100 Target Neighborhood Hits 1600 Shared Neighborhood Hits 35
SwissProt Accessions P13542, Q5SX36 Gene names Myh8, Myhsp
Domain
Architecture

No domain graphic available

Description Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).
EZRI_HUMAN
 
NC score 0.028139 (rank : 143) θ value 2.36792 (rank : 65)
Query Neighborhood Hits 100 Target Neighborhood Hits 663 Shared Neighborhood Hits 19
SwissProt Accessions P15311, P23714, Q96CU8, Q9NSJ4 Gene names VIL2
Domain
Architecture
Description Ezrin (p81) (Cytovillin) (Villin-2).
CCD11_MOUSE
 
NC score 0.028002 (rank : 144) θ value 4.03905 (rank : 75)
Query Neighborhood Hits 100 Target Neighborhood Hits 498 Shared Neighborhood Hits 18
SwissProt Accessions Q9D439 Gene names Ccdc11
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 11.
CENPE_HUMAN
 
NC score 0.027522 (rank : 145) θ value 0.47712 (rank : 48)
Query Neighborhood Hits 100 Target Neighborhood Hits 2060 Shared Neighborhood Hits 38
SwissProt Accessions Q02224 Gene names CENPE
Domain
Architecture
Description Centromeric protein E (CENP-E).
CCD27_MOUSE
 
NC score 0.026874 (rank : 146) θ value 8.99809 (rank : 97)
Query Neighborhood Hits 100 Target Neighborhood Hits 461 Shared Neighborhood Hits 16
SwissProt Accessions Q3V036 Gene names Ccdc27
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 27.
INCE_HUMAN
 
NC score 0.026236 (rank : 147) θ value 4.03905 (rank : 77)
Query Neighborhood Hits 100 Target Neighborhood Hits 978 Shared Neighborhood Hits 24
SwissProt Accessions Q9NQS7, Q5Y192 Gene names INCENP
Domain
Architecture
Description Inner centromere protein.
BRD2_HUMAN
 
NC score 0.025962 (rank : 148) θ value 1.81305 (rank : 59)
Query Neighborhood Hits 100 Target Neighborhood Hits 242 Shared Neighborhood Hits 7
SwissProt Accessions P25440, O00699, O00700, Q15310, Q5STC9, Q969U4 Gene names BRD2, KIAA9001, RING3
Domain
Architecture
Description Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).
GOGA1_MOUSE
 
NC score 0.025520 (rank : 149) θ value 8.99809 (rank : 98)
Query Neighborhood Hits 100 Target Neighborhood Hits 994 Shared Neighborhood Hits 29
SwissProt Accessions Q9CW79, Q80YB0 Gene names Golga1
Domain
Architecture
Description Golgin subfamily A member 1 (Golgin-97).
MFAP1_MOUSE
 
NC score 0.025348 (rank : 150) θ value 6.88961 (rank : 95)
Query Neighborhood Hits 100 Target Neighborhood Hits 353 Shared Neighborhood Hits 14
SwissProt Accessions Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5 Gene names Mfap1
Domain
Architecture

No domain graphic available

Description Microfibrillar-associated protein 1.
CENPF_HUMAN
 
NC score 0.024434 (rank : 151) θ value 6.88961 (rank : 92)
Query Neighborhood Hits 100 Target Neighborhood Hits 1932 Shared Neighborhood Hits 39
SwissProt Accessions P49454, Q13171, Q13246 Gene names CENPF
Domain
Architecture
Description Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).
MYH13_HUMAN
 
NC score 0.022960 (rank : 152) θ value 6.88961 (rank : 96)
Query Neighborhood Hits 100 Target Neighborhood Hits 1504 Shared Neighborhood Hits 29
SwissProt Accessions Q9UKX3, O95252 Gene names MYH13
Domain
Architecture
Description Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).
RBBP6_HUMAN
 
NC score 0.022892 (rank : 153) θ value 8.99809 (rank : 99)
Query Neighborhood Hits 100 Target Neighborhood Hits 1135 Shared Neighborhood Hits 19
SwissProt Accessions Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4 Gene names RBBP6, P2PR, PACT, RBQ1
Domain
Architecture

No domain graphic available

Description Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).
PLXD1_HUMAN
 
NC score 0.018641 (rank : 154) θ value 1.81305 (rank : 64)
Query Neighborhood Hits 100 Target Neighborhood Hits 89 Shared Neighborhood Hits 3
SwissProt Accessions Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2 Gene names PLXND1, KIAA0620
Domain
Architecture

No domain graphic available

Description Plexin-D1 precursor.
ERBB3_HUMAN
 
NC score 0.015093 (rank : 155) θ value 0.163984 (rank : 34)
Query Neighborhood Hits 100 Target Neighborhood Hits 918 Shared Neighborhood Hits 7
SwissProt Accessions P21860 Gene names ERBB3, HER3
Domain
Architecture
Description Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).
SAS10_HUMAN
 
NC score 0.013272 (rank : 156) θ value 8.99809 (rank : 100)
Query Neighborhood Hits 100 Target Neighborhood Hits 102 Shared Neighborhood Hits 2
SwissProt Accessions Q9NQZ2, Q6FI82 Gene names CRLZ1, SAS10
Domain
Architecture

No domain graphic available

Description Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).
SPTN2_HUMAN
 
NC score 0.013041 (rank : 157) θ value 5.27518 (rank : 90)
Query Neighborhood Hits 100 Target Neighborhood Hits 535 Shared Neighborhood Hits 21
SwissProt Accessions O15020, O14872, O14873 Gene names SPTBN2, KIAA0302
Domain
Architecture
Description Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).
ERBB3_MOUSE
 
NC score 0.012421 (rank : 158) θ value 1.06291 (rank : 55)
Query Neighborhood Hits 100 Target Neighborhood Hits 898 Shared Neighborhood Hits 8
SwissProt Accessions Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317 Gene names Erbb3
Domain
Architecture

No domain graphic available

Description Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).
CTRO_MOUSE
 
NC score 0.011986 (rank : 159) θ value 6.88961 (rank : 93)
Query Neighborhood Hits 100 Target Neighborhood Hits 2344 Shared Neighborhood Hits 32
SwissProt Accessions P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1 Gene names Cit
Domain
Architecture
Description Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).
CTRO_HUMAN
 
NC score 0.011732 (rank : 160) θ value 5.27518 (rank : 84)
Query Neighborhood Hits 100 Target Neighborhood Hits 2092 Shared Neighborhood Hits 31
SwissProt Accessions O14578, Q6XUH8, Q86UQ9, Q9UPZ7 Gene names CIT, KIAA0949, STK21
Domain
Architecture

No domain graphic available

Description Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).
LAMB2_HUMAN
 
NC score 0.011064 (rank : 161) θ value 1.81305 (rank : 61)
Query Neighborhood Hits 100 Target Neighborhood Hits 692 Shared Neighborhood Hits 14
SwissProt Accessions P55268, Q16321 Gene names LAMB2, LAMS
Domain
Architecture
Description Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).
CLK1_HUMAN
 
NC score 0.004127 (rank : 162) θ value 3.0926 (rank : 69)
Query Neighborhood Hits 100 Target Neighborhood Hits 756 Shared Neighborhood Hits 6
SwissProt Accessions P49759 Gene names CLK1, CLK
Domain
Architecture
Description Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1).
PCDGM_HUMAN
 
NC score 0.001649 (rank : 163) θ value 5.27518 (rank : 89)
Query Neighborhood Hits 100 Target Neighborhood Hits 152 Shared Neighborhood Hits 2
SwissProt Accessions Q9Y5F6, Q9Y5C2 Gene names PCDHGC5
Domain
Architecture
Description Protocadherin gamma C5 precursor (PCDH-gamma-C5).