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Network neighborhood for query Sequence : MYC_HUMAN

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MYC_HUMAN
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MYC_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	146
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_MOUSE
θ value	1.19313e-177 (rank : 2)	NC score	0.977625 (rank : 2)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	93
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCB_MOUSE
θ value	3.05695e-40 (rank : 3)	NC score	0.828112 (rank : 3)
Query Neighborhood Hits	146	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MYCN_HUMAN
θ value	1.37539e-32 (rank : 4)	NC score	0.820426 (rank : 5)
Query Neighborhood Hits	146	Target Neighborhood Hits	127	Shared Neighborhood Hits	54
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCL1_HUMAN
θ value	1.16434e-31 (rank : 5)	NC score	0.784758 (rank : 7)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCN_MOUSE
θ value	3.3877e-31 (rank : 6)	NC score	0.820753 (rank : 4)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
θ value	1.28732e-30 (rank : 7)	NC score	0.805373 (rank : 6)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYCL1_MOUSE
θ value	4.9032e-22 (rank : 8)	NC score	0.749576 (rank : 8)
Query Neighborhood Hits	146	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
θ value	1.63225e-17 (rank : 9)	NC score	0.715749 (rank : 9)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MAX_HUMAN
θ value	5.26297e-08 (rank : 10)	NC score	0.605366 (rank : 10)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
θ value	5.26297e-08 (rank : 11)	NC score	0.596838 (rank : 11)
Query Neighborhood Hits	146	Target Neighborhood Hits	139	Shared Neighborhood Hits	61
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MAD3_HUMAN
θ value	1.29631e-06 (rank : 12)	NC score	0.384205 (rank : 13)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	2.88788e-06 (rank : 13)	NC score	0.376419 (rank : 15)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	35
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MXI1_MOUSE
θ value	6.43352e-06 (rank : 14)	NC score	0.390235 (rank : 12)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
θ value	1.09739e-05 (rank : 15)	NC score	0.382735 (rank : 14)
Query Neighborhood Hits	146	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MNT_HUMAN
θ value	5.44631e-05 (rank : 16)	NC score	0.341711 (rank : 23)
Query Neighborhood Hits	146	Target Neighborhood Hits	496	Shared Neighborhood Hits	62
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	5.44631e-05 (rank : 17)	NC score	0.352710 (rank : 17)
Query Neighborhood Hits	146	Target Neighborhood Hits	432	Shared Neighborhood Hits	61
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MAD4_HUMAN
θ value	0.000270298 (rank : 18)	NC score	0.357277 (rank : 16)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

TFAP4_HUMAN
θ value	0.000270298 (rank : 19)	NC score	0.348206 (rank : 19)
Query Neighborhood Hits	146	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

PZRN3_HUMAN
θ value	0.000602161 (rank : 20)	NC score	0.064386 (rank : 112)
Query Neighborhood Hits	146	Target Neighborhood Hits	461	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

MAD4_MOUSE
θ value	0.00228821 (rank : 21)	NC score	0.313785 (rank : 24)
Query Neighborhood Hits	146	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

FIGLA_MOUSE
θ value	0.00298849 (rank : 22)	NC score	0.310022 (rank : 25)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

USF1_MOUSE
θ value	0.00298849 (rank : 23)	NC score	0.350622 (rank : 18)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MLX_HUMAN
θ value	0.00390308 (rank : 24)	NC score	0.287072 (rank : 28)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	0.00390308 (rank : 25)	NC score	0.289489 (rank : 27)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

USF2_HUMAN
θ value	0.00390308 (rank : 26)	NC score	0.347627 (rank : 20)
Query Neighborhood Hits	146	Target Neighborhood Hits	155	Shared Neighborhood Hits	52
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.00390308 (rank : 27)	NC score	0.345811 (rank : 21)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	50
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

ASCL2_MOUSE
θ value	0.00509761 (rank : 28)	NC score	0.224536 (rank : 38)
Query Neighborhood Hits	146	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

BHLH8_MOUSE
θ value	0.00665767 (rank : 29)	NC score	0.255401 (rank : 33)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

FIGLA_HUMAN
θ value	0.00665767 (rank : 30)	NC score	0.305521 (rank : 26)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	45
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

PZRN3_MOUSE
θ value	0.00869519 (rank : 31)	NC score	0.058284 (rank : 118)
Query Neighborhood Hits	146	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

USF1_HUMAN
θ value	0.00869519 (rank : 32)	NC score	0.345649 (rank : 22)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

PTF1A_HUMAN
θ value	0.0148317 (rank : 33)	NC score	0.219804 (rank : 41)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

SRBP1_HUMAN
θ value	0.0148317 (rank : 34)	NC score	0.241991 (rank : 35)
Query Neighborhood Hits	146	Target Neighborhood Hits	225	Shared Neighborhood Hits	46
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP2_HUMAN
θ value	0.0148317 (rank : 35)	NC score	0.269337 (rank : 30)
Query Neighborhood Hits	146	Target Neighborhood Hits	133	Shared Neighborhood Hits	45
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

SRBP1_MOUSE
θ value	0.0193708 (rank : 36)	NC score	0.234344 (rank : 37)
Query Neighborhood Hits	146	Target Neighborhood Hits	384	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

BHLH8_HUMAN
θ value	0.0252991 (rank : 37)	NC score	0.245535 (rank : 34)
Query Neighborhood Hits	146	Target Neighborhood Hits	123	Shared Neighborhood Hits	49
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MITF_HUMAN
θ value	0.0252991 (rank : 38)	NC score	0.261094 (rank : 31)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

WBS14_HUMAN
θ value	0.0252991 (rank : 39)	NC score	0.187429 (rank : 53)
Query Neighborhood Hits	146	Target Neighborhood Hits	273	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

ARNT_HUMAN
θ value	0.0330416 (rank : 40)	NC score	0.138468 (rank : 65)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

HAND1_MOUSE
θ value	0.0330416 (rank : 41)	NC score	0.190111 (rank : 52)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

KIF3A_HUMAN
θ value	0.0330416 (rank : 42)	NC score	0.034067 (rank : 137)
Query Neighborhood Hits	146	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3A_MOUSE
θ value	0.0330416 (rank : 43)	NC score	0.030717 (rank : 143)
Query Neighborhood Hits	146	Target Neighborhood Hits	715	Shared Neighborhood Hits	24
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MITF_MOUSE
θ value	0.0330416 (rank : 44)	NC score	0.258151 (rank : 32)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	46
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFE3_HUMAN
θ value	0.0431538 (rank : 45)	NC score	0.277509 (rank : 29)
Query Neighborhood Hits	146	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MYOG_HUMAN
θ value	0.0563607 (rank : 46)	NC score	0.173432 (rank : 57)
Query Neighborhood Hits	146	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
θ value	0.0563607 (rank : 47)	NC score	0.173831 (rank : 56)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

TWST1_HUMAN
θ value	0.0563607 (rank : 48)	NC score	0.204814 (rank : 48)
Query Neighborhood Hits	146	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
θ value	0.0563607 (rank : 49)	NC score	0.204453 (rank : 49)
Query Neighborhood Hits	146	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

ARNT_MOUSE
θ value	0.0736092 (rank : 50)	NC score	0.132762 (rank : 71)
Query Neighborhood Hits	146	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

SCX_MOUSE
θ value	0.0736092 (rank : 51)	NC score	0.177631 (rank : 55)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

TRHY_HUMAN
θ value	0.0736092 (rank : 52)	NC score	0.031015 (rank : 142)
Query Neighborhood Hits	146	Target Neighborhood Hits	1385	Shared Neighborhood Hits	41
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TWST2_HUMAN
θ value	0.0736092 (rank : 53)	NC score	0.205404 (rank : 47)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
θ value	0.0736092 (rank : 54)	NC score	0.205452 (rank : 46)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

ACINU_HUMAN
θ value	0.0961366 (rank : 55)	NC score	0.056742 (rank : 125)
Query Neighborhood Hits	146	Target Neighborhood Hits	828	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

HAND2_HUMAN
θ value	0.125558 (rank : 56)	NC score	0.209764 (rank : 42)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
θ value	0.125558 (rank : 57)	NC score	0.209764 (rank : 43)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

K0319_MOUSE
θ value	0.163984 (rank : 58)	NC score	0.049672 (rank : 128)
Query Neighborhood Hits	146	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

TFEB_HUMAN
θ value	0.163984 (rank : 59)	NC score	0.221557 (rank : 40)
Query Neighborhood Hits	146	Target Neighborhood Hits	111	Shared Neighborhood Hits	43
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.163984 (rank : 60)	NC score	0.222122 (rank : 39)
Query Neighborhood Hits	146	Target Neighborhood Hits	119	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

WBS14_MOUSE
θ value	0.163984 (rank : 61)	NC score	0.153340 (rank : 61)
Query Neighborhood Hits	146	Target Neighborhood Hits	171	Shared Neighborhood Hits	20
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ATOH1_HUMAN
θ value	0.21417 (rank : 62)	NC score	0.149349 (rank : 62)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
θ value	0.21417 (rank : 63)	NC score	0.148362 (rank : 63)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

ITSN1_HUMAN
θ value	0.21417 (rank : 64)	NC score	0.026362 (rank : 151)
Query Neighborhood Hits	146	Target Neighborhood Hits	1757	Shared Neighborhood Hits	46
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PTF1A_MOUSE
θ value	0.21417 (rank : 65)	NC score	0.208162 (rank : 44)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

TARA_HUMAN
θ value	0.21417 (rank : 66)	NC score	0.040752 (rank : 130)
Query Neighborhood Hits	146	Target Neighborhood Hits	1626	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

METL2_HUMAN
θ value	0.365318 (rank : 67)	NC score	0.046009 (rank : 129)
Query Neighborhood Hits	146	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

NEMO_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.038049 (rank : 132)
Query Neighborhood Hits	146	Target Neighborhood Hits	820	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

PF21A_HUMAN
θ value	0.365318 (rank : 69)	NC score	0.030585 (rank : 144)
Query Neighborhood Hits	146	Target Neighborhood Hits	303	Shared Neighborhood Hits	10
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

ARNT2_MOUSE
θ value	0.47712 (rank : 70)	NC score	0.122811 (rank : 74)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	35
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ITSN1_MOUSE
θ value	0.47712 (rank : 71)	NC score	0.025091 (rank : 153)
Query Neighborhood Hits	146	Target Neighborhood Hits	1669	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MAST4_HUMAN
θ value	0.47712 (rank : 72)	NC score	0.006644 (rank : 188)
Query Neighborhood Hits	146	Target Neighborhood Hits	1804	Shared Neighborhood Hits	29
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ARNT2_HUMAN
θ value	0.62314 (rank : 73)	NC score	0.121606 (rank : 75)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

CJ012_HUMAN
θ value	0.62314 (rank : 74)	NC score	0.034977 (rank : 135)
Query Neighborhood Hits	146	Target Neighborhood Hits	467	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

FATH_HUMAN
θ value	0.62314 (rank : 75)	NC score	0.003905 (rank : 192)
Query Neighborhood Hits	146	Target Neighborhood Hits	570	Shared Neighborhood Hits	3
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TOPB1_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.031265 (rank : 141)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

ASCL1_HUMAN
θ value	0.813845 (rank : 77)	NC score	0.207956 (rank : 45)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

NEMO_MOUSE
θ value	0.813845 (rank : 78)	NC score	0.032542 (rank : 138)
Query Neighborhood Hits	146	Target Neighborhood Hits	658	Shared Neighborhood Hits	24
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

SETX_HUMAN
θ value	0.813845 (rank : 79)	NC score	0.029152 (rank : 146)
Query Neighborhood Hits	146	Target Neighborhood Hits	368	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SNX23_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.026974 (rank : 149)
Query Neighborhood Hits	146	Target Neighborhood Hits	944	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

ABL1_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.000459 (rank : 195)
Query Neighborhood Hits	146	Target Neighborhood Hits	1220	Shared Neighborhood Hits	14
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

MINT_MOUSE
θ value	1.06291 (rank : 82)	NC score	0.029215 (rank : 145)
Query Neighborhood Hits	146	Target Neighborhood Hits	1514	Shared Neighborhood Hits	39
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ASCL1_MOUSE
θ value	1.38821 (rank : 83)	NC score	0.198213 (rank : 51)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	41
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

BHLH2_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.086020 (rank : 97)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	33
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
θ value	1.38821 (rank : 85)	NC score	0.085370 (rank : 98)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

CE152_HUMAN
θ value	1.38821 (rank : 86)	NC score	0.023438 (rank : 157)
Query Neighborhood Hits	146	Target Neighborhood Hits	976	Shared Neighborhood Hits	29
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

MYF6_MOUSE
θ value	1.38821 (rank : 87)	NC score	0.159627 (rank : 59)
Query Neighborhood Hits	146	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

UBP28_MOUSE
θ value	1.38821 (rank : 88)	NC score	0.028137 (rank : 148)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

CCD91_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.034167 (rank : 136)
Query Neighborhood Hits	146	Target Neighborhood Hits	868	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

DHX16_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.021734 (rank : 161)
Query Neighborhood Hits	146	Target Neighborhood Hits	356	Shared Neighborhood Hits	19
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

MARK4_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.001151 (rank : 193)
Query Neighborhood Hits	146	Target Neighborhood Hits	886	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

MYF6_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.163252 (rank : 58)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

TCF15_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.132045 (rank : 72)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

URFB1_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.031679 (rank : 139)
Query Neighborhood Hits	146	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

CTRO_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.010505 (rank : 183)
Query Neighborhood Hits	146	Target Neighborhood Hits	2344	Shared Neighborhood Hits	50
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

FBX38_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.029091 (rank : 147)
Query Neighborhood Hits	146	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

HAND1_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.178779 (rank : 54)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

MARK4_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.001018 (rank : 194)
Query Neighborhood Hits	146	Target Neighborhood Hits	898	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MY18A_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.019311 (rank : 166)
Query Neighborhood Hits	146	Target Neighborhood Hits	1989	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SFPQ_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.019071 (rank : 169)
Query Neighborhood Hits	146	Target Neighborhood Hits	958	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

XE7_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.035538 (rank : 134)
Query Neighborhood Hits	146	Target Neighborhood Hits	738	Shared Neighborhood Hits	33
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ZEP2_MOUSE
θ value	2.36792 (rank : 102)	NC score	0.004295 (rank : 191)
Query Neighborhood Hits	146	Target Neighborhood Hits	964	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

BHLH3_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.092008 (rank : 92)
Query Neighborhood Hits	146	Target Neighborhood Hits	106	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BSN_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.026481 (rank : 150)
Query Neighborhood Hits	146	Target Neighborhood Hits	1537	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CD45_MOUSE
θ value	3.0926 (rank : 105)	NC score	0.005082 (rank : 189)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

DIDO1_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.017321 (rank : 174)
Query Neighborhood Hits	146	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

K0586_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.038732 (rank : 131)
Query Neighborhood Hits	146	Target Neighborhood Hits	311	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

MYF5_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.134449 (rank : 68)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF5_MOUSE
θ value	3.0926 (rank : 109)	NC score	0.135529 (rank : 66)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYOD1_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.133339 (rank : 70)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MYOD1_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.135248 (rank : 67)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

PF21A_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.025821 (rank : 152)
Query Neighborhood Hits	146	Target Neighborhood Hits	285	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PPIG_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.014120 (rank : 180)
Query Neighborhood Hits	146	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RPGR_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.012821 (rank : 181)
Query Neighborhood Hits	146	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

ZFYV1_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.019753 (rank : 163)
Query Neighborhood Hits	146	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ATF6A_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.019625 (rank : 164)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

BCL7A_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.016511 (rank : 175)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

EVPL_MOUSE
θ value	4.03905 (rank : 118)	NC score	0.022501 (rank : 158)
Query Neighborhood Hits	146	Target Neighborhood Hits	952	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

FYB_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.023988 (rank : 155)
Query Neighborhood Hits	146	Target Neighborhood Hits	379	Shared Neighborhood Hits	18
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

NIN_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.019292 (rank : 167)
Query Neighborhood Hits	146	Target Neighborhood Hits	1416	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PITM1_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.009483 (rank : 184)
Query Neighborhood Hits	146	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

PP4R1_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.014916 (rank : 177)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

SFPQ_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.018579 (rank : 171)
Query Neighborhood Hits	146	Target Neighborhood Hits	986	Shared Neighborhood Hits	25
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TCF15_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.122894 (rank : 73)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

TSH1_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.007393 (rank : 187)
Query Neighborhood Hits	146	Target Neighborhood Hits	675	Shared Neighborhood Hits	9
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

CTRO_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.008003 (rank : 186)
Query Neighborhood Hits	146	Target Neighborhood Hits	2092	Shared Neighborhood Hits	43
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

OXR1_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.020350 (rank : 162)
Query Neighborhood Hits	146	Target Neighborhood Hits	282	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

PLEC1_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.012708 (rank : 182)
Query Neighborhood Hits	146	Target Neighborhood Hits	1326	Shared Neighborhood Hits	33
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PLXA1_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.005054 (rank : 190)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

SYCC_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.018082 (rank : 172)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER72, O88303, Q8BP81, Q8CAY7, Q8CCE3, Q8K0S4, Q9ER68	Gene names	Cars
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

TTC14_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.031298 (rank : 140)
Query Neighborhood Hits	146	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

ATRX_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.017688 (rank : 173)
Query Neighborhood Hits	146	Target Neighborhood Hits	842	Shared Neighborhood Hits	30
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BHLH3_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.086308 (rank : 96)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

CEBPE_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.023844 (rank : 156)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

MUC1_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.014582 (rank : 178)
Query Neighborhood Hits	146	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

RAD50_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.019024 (rank : 170)
Query Neighborhood Hits	146	Target Neighborhood Hits	1366	Shared Neighborhood Hits	40
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SAFB2_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.019101 (rank : 168)
Query Neighborhood Hits	146	Target Neighborhood Hits	581	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

CCD13_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.019578 (rank : 165)
Query Neighborhood Hits	146	Target Neighborhood Hits	721	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

DOT1L_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.014266 (rank : 179)
Query Neighborhood Hits	146	Target Neighborhood Hits	660	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PRD16_HUMAN
θ value	8.99809 (rank : 140)	NC score	-0.004212 (rank : 196)
Query Neighborhood Hits	146	Target Neighborhood Hits	832	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

RGNEF_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.022282 (rank : 159)
Query Neighborhood Hits	146	Target Neighborhood Hits	641	Shared Neighborhood Hits	29
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

SAFB2_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.022134 (rank : 160)
Query Neighborhood Hits	146	Target Neighborhood Hits	720	Shared Neighborhood Hits	19
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SRRM2_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.024748 (rank : 154)
Query Neighborhood Hits	146	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYCC_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.016506 (rank : 176)
Query Neighborhood Hits	146	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P49589, Q53XI8, Q9HD24, Q9HD25	Gene names	CARS
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

SYNJ1_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.009060 (rank : 185)
Query Neighborhood Hits	146	Target Neighborhood Hits	498	Shared Neighborhood Hits	15
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TARA_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.035991 (rank : 133)
Query Neighborhood Hits	146	Target Neighborhood Hits	1133	Shared Neighborhood Hits	39
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ASCL2_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.157507 (rank : 60)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

ASCL3_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.139431 (rank : 64)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

ASCL3_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.134122 (rank : 69)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

BHLH4_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.064624 (rank : 110)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BHLH4_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.062473 (rank : 113)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BMAL1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.079255 (rank : 102)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.078606 (rank : 103)
Query Neighborhood Hits	146	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

HEN1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.100064 (rank : 85)
Query Neighborhood Hits	146	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.101417 (rank : 83)
Query Neighborhood Hits	146	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.098525 (rank : 87)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.097938 (rank : 89)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEY1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.056996 (rank : 124)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.057514 (rank : 122)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.059286 (rank : 115)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.060798 (rank : 114)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

ID1_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.073017 (rank : 106)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID1_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.068746 (rank : 107)
Query Neighborhood Hits	146	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

LYL1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.104121 (rank : 79)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

LYL1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.102733 (rank : 81)
Query Neighborhood Hits	146	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

MAD1_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.201162 (rank : 50)
Query Neighborhood Hits	146	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.239646 (rank : 36)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MUSC_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.086366 (rank : 95)
Query Neighborhood Hits	146	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

MUSC_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.088083 (rank : 94)
Query Neighborhood Hits	146	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

NDF1_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.074691 (rank : 105)
Query Neighborhood Hits	146	Target Neighborhood Hits	186	Shared Neighborhood Hits	38
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF1_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.075833 (rank : 104)
Query Neighborhood Hits	146	Target Neighborhood Hits	209	Shared Neighborhood Hits	38
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF2_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.095650 (rank : 90)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.095285 (rank : 91)
Query Neighborhood Hits	146	Target Neighborhood Hits	111	Shared Neighborhood Hits	37
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF4_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.064395 (rank : 111)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

NDF4_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.065101 (rank : 109)
Query Neighborhood Hits	146	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

NDF6_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.058685 (rank : 117)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.058283 (rank : 119)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

NGN1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.085109 (rank : 99)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

NGN1_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.088453 (rank : 93)
Query Neighborhood Hits	146	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

NGN2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.098428 (rank : 88)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN2_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.100279 (rank : 84)
Query Neighborhood Hits	146	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NGN3_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.113408 (rank : 78)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

NGN3_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.103572 (rank : 80)
Query Neighborhood Hits	146	Target Neighborhood Hits	90	Shared Neighborhood Hits	38
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

OLIG1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.059078 (rank : 116)
Query Neighborhood Hits	146	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OLIG1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.057559 (rank : 121)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

OLIG2_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.058170 (rank : 120)
Query Neighborhood Hits	146	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG2_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.057263 (rank : 123)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

OLIG3_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.054685 (rank : 127)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

OLIG3_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.055738 (rank : 126)
Query Neighborhood Hits	146	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

TAL1_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.114059 (rank : 77)
Query Neighborhood Hits	146	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

TAL1_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.115595 (rank : 76)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL2_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.098780 (rank : 86)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

TAL2_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.101777 (rank : 82)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

TCF21_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.084503 (rank : 100)
Query Neighborhood Hits	146	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.083853 (rank : 101)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCFL5_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.067639 (rank : 108)
Query Neighborhood Hits	146	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

Hits sorted by NC score

MYC_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	146
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_MOUSE
NC score	0.977625 (rank : 2)	θ value	1.19313e-177 (rank : 2)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	93
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCB_MOUSE
NC score	0.828112 (rank : 3)	θ value	3.05695e-40 (rank : 3)
Query Neighborhood Hits	146	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MYCN_MOUSE
NC score	0.820753 (rank : 4)	θ value	3.3877e-31 (rank : 6)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.820426 (rank : 5)	θ value	1.37539e-32 (rank : 4)
Query Neighborhood Hits	146	Target Neighborhood Hits	127	Shared Neighborhood Hits	54
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
NC score	0.805373 (rank : 6)	θ value	1.28732e-30 (rank : 7)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYCL1_HUMAN
NC score	0.784758 (rank : 7)	θ value	1.16434e-31 (rank : 5)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
NC score	0.749576 (rank : 8)	θ value	4.9032e-22 (rank : 8)
Query Neighborhood Hits	146	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
NC score	0.715749 (rank : 9)	θ value	1.63225e-17 (rank : 9)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	37
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MAX_HUMAN
NC score	0.605366 (rank : 10)	θ value	5.26297e-08 (rank : 10)
Query Neighborhood Hits	146	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
NC score	0.596838 (rank : 11)	θ value	5.26297e-08 (rank : 11)
Query Neighborhood Hits	146	Target Neighborhood Hits	139	Shared Neighborhood Hits	61
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MXI1_MOUSE
NC score	0.390235 (rank : 12)	θ value	6.43352e-06 (rank : 14)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD3_HUMAN
NC score	0.384205 (rank : 13)	θ value	1.29631e-06 (rank : 12)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MXI1_HUMAN
NC score	0.382735 (rank : 14)	θ value	1.09739e-05 (rank : 15)
Query Neighborhood Hits	146	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD3_MOUSE
NC score	0.376419 (rank : 15)	θ value	2.88788e-06 (rank : 13)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	35
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAD4_HUMAN
NC score	0.357277 (rank : 16)	θ value	0.000270298 (rank : 18)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MNT_MOUSE
NC score	0.352710 (rank : 17)	θ value	5.44631e-05 (rank : 17)
Query Neighborhood Hits	146	Target Neighborhood Hits	432	Shared Neighborhood Hits	61
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

USF1_MOUSE
NC score	0.350622 (rank : 18)	θ value	0.00298849 (rank : 23)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

TFAP4_HUMAN
NC score	0.348206 (rank : 19)	θ value	0.000270298 (rank : 19)
Query Neighborhood Hits	146	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

USF2_HUMAN
NC score	0.347627 (rank : 20)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	146	Target Neighborhood Hits	155	Shared Neighborhood Hits	52
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
NC score	0.345811 (rank : 21)	θ value	0.00390308 (rank : 27)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	50
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

USF1_HUMAN
NC score	0.345649 (rank : 22)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MNT_HUMAN
NC score	0.341711 (rank : 23)	θ value	5.44631e-05 (rank : 16)
Query Neighborhood Hits	146	Target Neighborhood Hits	496	Shared Neighborhood Hits	62
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MAD4_MOUSE
NC score	0.313785 (rank : 24)	θ value	0.00228821 (rank : 21)
Query Neighborhood Hits	146	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

FIGLA_MOUSE
NC score	0.310022 (rank : 25)	θ value	0.00298849 (rank : 22)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

FIGLA_HUMAN
NC score	0.305521 (rank : 26)	θ value	0.00665767 (rank : 30)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	45
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MLX_MOUSE
NC score	0.289489 (rank : 27)	θ value	0.00390308 (rank : 25)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.287072 (rank : 28)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

TFE3_HUMAN
NC score	0.277509 (rank : 29)	θ value	0.0431538 (rank : 45)
Query Neighborhood Hits	146	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

SRBP2_HUMAN
NC score	0.269337 (rank : 30)	θ value	0.0148317 (rank : 35)
Query Neighborhood Hits	146	Target Neighborhood Hits	133	Shared Neighborhood Hits	45
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

MITF_HUMAN
NC score	0.261094 (rank : 31)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.258151 (rank : 32)	θ value	0.0330416 (rank : 44)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	46
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

BHLH8_MOUSE
NC score	0.255401 (rank : 33)	θ value	0.00665767 (rank : 29)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_HUMAN
NC score	0.245535 (rank : 34)	θ value	0.0252991 (rank : 37)
Query Neighborhood Hits	146	Target Neighborhood Hits	123	Shared Neighborhood Hits	49
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

SRBP1_HUMAN
NC score	0.241991 (rank : 35)	θ value	0.0148317 (rank : 34)
Query Neighborhood Hits	146	Target Neighborhood Hits	225	Shared Neighborhood Hits	46
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MAD1_MOUSE
NC score	0.239646 (rank : 36)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

SRBP1_MOUSE
NC score	0.234344 (rank : 37)	θ value	0.0193708 (rank : 36)
Query Neighborhood Hits	146	Target Neighborhood Hits	384	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ASCL2_MOUSE
NC score	0.224536 (rank : 38)	θ value	0.00509761 (rank : 28)
Query Neighborhood Hits	146	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

TFEB_MOUSE
NC score	0.222122 (rank : 39)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	146	Target Neighborhood Hits	119	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.221557 (rank : 40)	θ value	0.163984 (rank : 59)
Query Neighborhood Hits	146	Target Neighborhood Hits	111	Shared Neighborhood Hits	43
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

PTF1A_HUMAN
NC score	0.219804 (rank : 41)	θ value	0.0148317 (rank : 33)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

HAND2_HUMAN
NC score	0.209764 (rank : 42)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
NC score	0.209764 (rank : 43)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

PTF1A_MOUSE
NC score	0.208162 (rank : 44)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

ASCL1_HUMAN
NC score	0.207956 (rank : 45)	θ value	0.813845 (rank : 77)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

TWST2_MOUSE
NC score	0.205452 (rank : 46)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_HUMAN
NC score	0.205404 (rank : 47)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST1_HUMAN
NC score	0.204814 (rank : 48)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	146	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
NC score	0.204453 (rank : 49)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	146	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

MAD1_HUMAN
NC score	0.201162 (rank : 50)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	146	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

ASCL1_MOUSE
NC score	0.198213 (rank : 51)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	41
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

HAND1_MOUSE
NC score	0.190111 (rank : 52)	θ value	0.0330416 (rank : 41)
Query Neighborhood Hits	146	Target Neighborhood Hits	107	Shared Neighborhood Hits	44
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

WBS14_HUMAN
NC score	0.187429 (rank : 53)	θ value	0.0252991 (rank : 39)
Query Neighborhood Hits	146	Target Neighborhood Hits	273	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

HAND1_HUMAN
NC score	0.178779 (rank : 54)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

SCX_MOUSE
NC score	0.177631 (rank : 55)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

MYOG_MOUSE
NC score	0.173831 (rank : 56)	θ value	0.0563607 (rank : 47)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

MYOG_HUMAN
NC score	0.173432 (rank : 57)	θ value	0.0563607 (rank : 46)
Query Neighborhood Hits	146	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYF6_HUMAN
NC score	0.163252 (rank : 58)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
NC score	0.159627 (rank : 59)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	146	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

ASCL2_HUMAN
NC score	0.157507 (rank : 60)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

WBS14_MOUSE
NC score	0.153340 (rank : 61)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	146	Target Neighborhood Hits	171	Shared Neighborhood Hits	20
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ATOH1_HUMAN
NC score	0.149349 (rank : 62)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
NC score	0.148362 (rank : 63)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

ASCL3_HUMAN
NC score	0.139431 (rank : 64)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

ARNT_HUMAN
NC score	0.138468 (rank : 65)	θ value	0.0330416 (rank : 40)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MYF5_MOUSE
NC score	0.135529 (rank : 66)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYOD1_MOUSE
NC score	0.135248 (rank : 67)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MYF5_HUMAN
NC score	0.134449 (rank : 68)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

ASCL3_MOUSE
NC score	0.134122 (rank : 69)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

MYOD1_HUMAN
NC score	0.133339 (rank : 70)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

ARNT_MOUSE
NC score	0.132762 (rank : 71)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	146	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

TCF15_MOUSE
NC score	0.132045 (rank : 72)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

TCF15_HUMAN
NC score	0.122894 (rank : 73)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

ARNT2_MOUSE
NC score	0.122811 (rank : 74)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	35
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.121606 (rank : 75)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

TAL1_MOUSE
NC score	0.115595 (rank : 76)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	44
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL1_HUMAN
NC score	0.114059 (rank : 77)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	146	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

NGN3_HUMAN
NC score	0.113408 (rank : 78)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

LYL1_HUMAN
NC score	0.104121 (rank : 79)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

NGN3_MOUSE
NC score	0.103572 (rank : 80)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	146	Target Neighborhood Hits	90	Shared Neighborhood Hits	38
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

LYL1_MOUSE
NC score	0.102733 (rank : 81)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	146	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

TAL2_MOUSE
NC score	0.101777 (rank : 82)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

HEN1_MOUSE
NC score	0.101417 (rank : 83)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	146	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

NGN2_MOUSE
NC score	0.100279 (rank : 84)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	146	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

HEN1_HUMAN
NC score	0.100064 (rank : 85)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	146	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

TAL2_HUMAN
NC score	0.098780 (rank : 86)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

HEN2_HUMAN
NC score	0.098525 (rank : 87)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

NGN2_HUMAN
NC score	0.098428 (rank : 88)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

HEN2_MOUSE
NC score	0.097938 (rank : 89)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

NDF2_HUMAN
NC score	0.095650 (rank : 90)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
NC score	0.095285 (rank : 91)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	146	Target Neighborhood Hits	111	Shared Neighborhood Hits	37
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

BHLH3_HUMAN
NC score	0.092008 (rank : 92)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	146	Target Neighborhood Hits	106	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

NGN1_MOUSE
NC score	0.088453 (rank : 93)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	146	Target Neighborhood Hits	87	Shared Neighborhood Hits	36
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

MUSC_MOUSE
NC score	0.088083 (rank : 94)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	146	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MUSC_HUMAN
NC score	0.086366 (rank : 95)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	146	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

BHLH3_MOUSE
NC score	0.086308 (rank : 96)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BHLH2_HUMAN
NC score	0.086020 (rank : 97)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	33
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
NC score	0.085370 (rank : 98)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

NGN1_HUMAN
NC score	0.085109 (rank : 99)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	146	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

TCF21_HUMAN
NC score	0.084503 (rank : 100)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	146	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
NC score	0.083853 (rank : 101)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

BMAL1_HUMAN
NC score	0.079255 (rank : 102)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.078606 (rank : 103)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	146	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

NDF1_MOUSE
NC score	0.075833 (rank : 104)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	146	Target Neighborhood Hits	209	Shared Neighborhood Hits	38
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF1_HUMAN
NC score	0.074691 (rank : 105)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	146	Target Neighborhood Hits	186	Shared Neighborhood Hits	38
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

ID1_HUMAN
NC score	0.073017 (rank : 106)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID1_MOUSE
NC score	0.068746 (rank : 107)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	146	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

TCFL5_HUMAN
NC score	0.067639 (rank : 108)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	146	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

NDF4_MOUSE
NC score	0.065101 (rank : 109)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	146	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

BHLH4_HUMAN
NC score	0.064624 (rank : 110)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	146	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

NDF4_HUMAN
NC score	0.064395 (rank : 111)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

PZRN3_HUMAN
NC score	0.064386 (rank : 112)	θ value	0.000602161 (rank : 20)
Query Neighborhood Hits	146	Target Neighborhood Hits	461	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

BHLH4_MOUSE
NC score	0.062473 (rank : 113)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	146	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

HEY2_MOUSE
NC score	0.060798 (rank : 114)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY2_HUMAN
NC score	0.059286 (rank : 115)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

OLIG1_HUMAN
NC score	0.059078 (rank : 116)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	146	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

NDF6_HUMAN
NC score	0.058685 (rank : 117)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

PZRN3_MOUSE
NC score	0.058284 (rank : 118)	θ value	0.00869519 (rank : 31)
Query Neighborhood Hits	146	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

NDF6_MOUSE
NC score	0.058283 (rank : 119)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

OLIG2_HUMAN
NC score	0.058170 (rank : 120)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	146	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG1_MOUSE
NC score	0.057559 (rank : 121)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

HEY1_MOUSE
NC score	0.057514 (rank : 122)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

OLIG2_MOUSE
NC score	0.057263 (rank : 123)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

HEY1_HUMAN
NC score	0.056996 (rank : 124)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

ACINU_HUMAN
NC score	0.056742 (rank : 125)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	146	Target Neighborhood Hits	828	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

OLIG3_MOUSE
NC score	0.055738 (rank : 126)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	146	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

OLIG3_HUMAN
NC score	0.054685 (rank : 127)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

K0319_MOUSE
NC score	0.049672 (rank : 128)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	146	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

METL2_HUMAN
NC score	0.046009 (rank : 129)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	146	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

TARA_HUMAN
NC score	0.040752 (rank : 130)	θ value	0.21417 (rank : 66)
Query Neighborhood Hits	146	Target Neighborhood Hits	1626	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

K0586_HUMAN
NC score	0.038732 (rank : 131)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	146	Target Neighborhood Hits	311	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

NEMO_HUMAN
NC score	0.038049 (rank : 132)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	146	Target Neighborhood Hits	820	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

TARA_MOUSE
NC score	0.035991 (rank : 133)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	146	Target Neighborhood Hits	1133	Shared Neighborhood Hits	39
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

XE7_HUMAN
NC score	0.035538 (rank : 134)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	146	Target Neighborhood Hits	738	Shared Neighborhood Hits	33
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

CJ012_HUMAN
NC score	0.034977 (rank : 135)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	146	Target Neighborhood Hits	467	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CCD91_HUMAN
NC score	0.034167 (rank : 136)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	146	Target Neighborhood Hits	868	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

KIF3A_HUMAN
NC score	0.034067 (rank : 137)	θ value	0.0330416 (rank : 42)
Query Neighborhood Hits	146	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

NEMO_MOUSE
NC score	0.032542 (rank : 138)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	146	Target Neighborhood Hits	658	Shared Neighborhood Hits	24
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

URFB1_HUMAN
NC score	0.031679 (rank : 139)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	146	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

TTC14_HUMAN
NC score	0.031298 (rank : 140)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	146	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

TOPB1_HUMAN
NC score	0.031265 (rank : 141)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

TRHY_HUMAN
NC score	0.031015 (rank : 142)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	146	Target Neighborhood Hits	1385	Shared Neighborhood Hits	41
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

KIF3A_MOUSE
NC score	0.030717 (rank : 143)	θ value	0.0330416 (rank : 43)
Query Neighborhood Hits	146	Target Neighborhood Hits	715	Shared Neighborhood Hits	24
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

PF21A_HUMAN
NC score	0.030585 (rank : 144)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	146	Target Neighborhood Hits	303	Shared Neighborhood Hits	10
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

MINT_MOUSE
NC score	0.029215 (rank : 145)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	146	Target Neighborhood Hits	1514	Shared Neighborhood Hits	39
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SETX_HUMAN
NC score	0.029152 (rank : 146)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	146	Target Neighborhood Hits	368	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

FBX38_HUMAN
NC score	0.029091 (rank : 147)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	146	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

UBP28_MOUSE
NC score	0.028137 (rank : 148)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

SNX23_HUMAN
NC score	0.026974 (rank : 149)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	146	Target Neighborhood Hits	944	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

BSN_HUMAN
NC score	0.026481 (rank : 150)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	146	Target Neighborhood Hits	1537	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ITSN1_HUMAN
NC score	0.026362 (rank : 151)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	146	Target Neighborhood Hits	1757	Shared Neighborhood Hits	46
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PF21A_MOUSE
NC score	0.025821 (rank : 152)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	146	Target Neighborhood Hits	285	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

ITSN1_MOUSE
NC score	0.025091 (rank : 153)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	146	Target Neighborhood Hits	1669	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SRRM2_HUMAN
NC score	0.024748 (rank : 154)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	146	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

FYB_HUMAN
NC score	0.023988 (rank : 155)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	146	Target Neighborhood Hits	379	Shared Neighborhood Hits	18
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

CEBPE_HUMAN
NC score	0.023844 (rank : 156)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CE152_HUMAN
NC score	0.023438 (rank : 157)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	146	Target Neighborhood Hits	976	Shared Neighborhood Hits	29
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

EVPL_MOUSE
NC score	0.022501 (rank : 158)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	146	Target Neighborhood Hits	952	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

RGNEF_MOUSE
NC score	0.022282 (rank : 159)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	146	Target Neighborhood Hits	641	Shared Neighborhood Hits	29
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

SAFB2_HUMAN
NC score	0.022134 (rank : 160)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	146	Target Neighborhood Hits	720	Shared Neighborhood Hits	19
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

DHX16_HUMAN
NC score	0.021734 (rank : 161)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	146	Target Neighborhood Hits	356	Shared Neighborhood Hits	19
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

OXR1_HUMAN
NC score	0.020350 (rank : 162)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	146	Target Neighborhood Hits	282	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

ZFYV1_HUMAN
NC score	0.019753 (rank : 163)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	146	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ATF6A_HUMAN
NC score	0.019625 (rank : 164)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CCD13_HUMAN
NC score	0.019578 (rank : 165)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	146	Target Neighborhood Hits	721	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

MY18A_MOUSE
NC score	0.019311 (rank : 166)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	146	Target Neighborhood Hits	1989	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NIN_HUMAN
NC score	0.019292 (rank : 167)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	146	Target Neighborhood Hits	1416	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

SAFB2_MOUSE
NC score	0.019101 (rank : 168)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	146	Target Neighborhood Hits	581	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SFPQ_MOUSE
NC score	0.019071 (rank : 169)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	146	Target Neighborhood Hits	958	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

RAD50_MOUSE
NC score	0.019024 (rank : 170)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	146	Target Neighborhood Hits	1366	Shared Neighborhood Hits	40
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SFPQ_HUMAN
NC score	0.018579 (rank : 171)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	146	Target Neighborhood Hits	986	Shared Neighborhood Hits	25
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SYCC_MOUSE
NC score	0.018082 (rank : 172)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER72, O88303, Q8BP81, Q8CAY7, Q8CCE3, Q8K0S4, Q9ER68	Gene names	Cars
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

ATRX_HUMAN
NC score	0.017688 (rank : 173)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	146	Target Neighborhood Hits	842	Shared Neighborhood Hits	30
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

DIDO1_HUMAN
NC score	0.017321 (rank : 174)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	146	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

BCL7A_MOUSE
NC score	0.016511 (rank : 175)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

SYCC_HUMAN
NC score	0.016506 (rank : 176)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	146	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P49589, Q53XI8, Q9HD24, Q9HD25	Gene names	CARS
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

PP4R1_MOUSE
NC score	0.014916 (rank : 177)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	146	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

MUC1_MOUSE
NC score	0.014582 (rank : 178)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	146	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

DOT1L_HUMAN
NC score	0.014266 (rank : 179)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	146	Target Neighborhood Hits	660	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PPIG_HUMAN
NC score	0.014120 (rank : 180)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	146	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RPGR_HUMAN
NC score	0.012821 (rank : 181)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	146	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

PLEC1_HUMAN
NC score	0.012708 (rank : 182)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	146	Target Neighborhood Hits	1326	Shared Neighborhood Hits	33
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

CTRO_MOUSE
NC score	0.010505 (rank : 183)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	146	Target Neighborhood Hits	2344	Shared Neighborhood Hits	50
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

PITM1_HUMAN
NC score	0.009483 (rank : 184)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	146	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

SYNJ1_HUMAN
NC score	0.009060 (rank : 185)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	146	Target Neighborhood Hits	498	Shared Neighborhood Hits	15
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CTRO_HUMAN
NC score	0.008003 (rank : 186)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	146	Target Neighborhood Hits	2092	Shared Neighborhood Hits	43
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

TSH1_MOUSE
NC score	0.007393 (rank : 187)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	146	Target Neighborhood Hits	675	Shared Neighborhood Hits	9
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

MAST4_HUMAN
NC score	0.006644 (rank : 188)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	146	Target Neighborhood Hits	1804	Shared Neighborhood Hits	29
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CD45_MOUSE
NC score	0.005082 (rank : 189)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PLXA1_HUMAN
NC score	0.005054 (rank : 190)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

ZEP2_MOUSE
NC score	0.004295 (rank : 191)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	146	Target Neighborhood Hits	964	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

FATH_HUMAN
NC score	0.003905 (rank : 192)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	146	Target Neighborhood Hits	570	Shared Neighborhood Hits	3
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

MARK4_HUMAN
NC score	0.001151 (rank : 193)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	146	Target Neighborhood Hits	886	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

MARK4_MOUSE
NC score	0.001018 (rank : 194)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	146	Target Neighborhood Hits	898	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

ABL1_HUMAN
NC score	0.000459 (rank : 195)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	146	Target Neighborhood Hits	1220	Shared Neighborhood Hits	14
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

PRD16_HUMAN
NC score	-0.004212 (rank : 196)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	146	Target Neighborhood Hits	832	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).