Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PP4R1_MOUSE

For an explanation of this page, click here

PP4R1_MOUSE
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PP4R1_HUMAN
θ value	0 (rank : 1)	NC score	0.978480 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4RL_HUMAN
θ value	3.88293e-136 (rank : 3)	NC score	0.950741 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

2AAA_HUMAN
θ value	6.00763e-12 (rank : 4)	NC score	0.454289 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
θ value	6.00763e-12 (rank : 5)	NC score	0.455110 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAB_MOUSE
θ value	3.89403e-11 (rank : 6)	NC score	0.437551 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_HUMAN
θ value	5.08577e-11 (rank : 7)	NC score	0.434015 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

NCOR2_HUMAN
θ value	0.00869519 (rank : 8)	NC score	0.056671 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	870	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

AZI1_MOUSE
θ value	0.0193708 (rank : 9)	NC score	0.030173 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	990	Shared Neighborhood Hits	17
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

HEMGN_MOUSE
θ value	0.0252991 (rank : 10)	NC score	0.078610 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

CD2L1_MOUSE
θ value	0.0431538 (rank : 11)	NC score	0.009597 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	1463	Shared Neighborhood Hits	16
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

NTKL_HUMAN
θ value	0.0736092 (rank : 12)	NC score	0.085865 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

CA106_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.054288 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

NTKL_MOUSE
θ value	0.21417 (rank : 14)	NC score	0.071445 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

PABP2_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.044621 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PI3R4_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.081974 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

SET1A_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.037568 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

PI3R4_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.080079 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	535	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

ROBO1_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.009926 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	529	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

ATBF1_MOUSE
θ value	0.47712 (rank : 20)	NC score	0.015918 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	1841	Shared Neighborhood Hits	29
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BRPF1_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.025746 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	259	Shared Neighborhood Hits	12
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

LAP2_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.020408 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	499	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

NOB1_HUMAN
θ value	0.47712 (rank : 23)	NC score	0.076009 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULX3, Q7L6B7, Q7M4M4, Q7Z4B5, Q9NWB0	Gene names	NOB1, ART4, NOB1P, PSMD8BP1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1 (Protein ART-4) (Phosphorylation regulatory protein HP-10).

NOB1_MOUSE
θ value	0.47712 (rank : 24)	NC score	0.081432 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BW10, Q7TPR3, Q9CRD7	Gene names	Nob1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1.

CI040_MOUSE
θ value	0.62314 (rank : 25)	NC score	0.092467 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

MAP9_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.031233 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	518	Shared Neighborhood Hits	13
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MILK2_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.023683 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	457	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

RAD52_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.044338 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P43352	Gene names	Rad52
Domain Architecture
Description	DNA repair protein RAD52 homolog.

NCOA6_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.034616 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	1076	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SRBS1_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.027927 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	396	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRRM2_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.035521 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	1470	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WIRE_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.040575 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	310	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

EFS_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.023655 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	389	Shared Neighborhood Hits	11
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

IWS1_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.029915 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	1241	Shared Neighborhood Hits	32
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KI13B_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.010703 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	492	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

MYCD_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.023788 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

ATX7_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.030099 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

MAP4_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.028738 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PABP2_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.035036 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

RLF_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.008125 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	775	Shared Neighborhood Hits	7
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

FGD5_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.013090 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

MUC1_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.030374 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	388	Shared Neighborhood Hits	19
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NCOA6_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.032610 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	1202	Shared Neighborhood Hits	31
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ADDB_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.017177 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

CI040_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.092027 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IXQ3, Q9NWD3	Gene names	C9orf40
Domain Architecture	No domain graphic available
Description	Protein C9orf40.

HRBL_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.017386 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ING3_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.026976 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.027349 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

SRBS1_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.022638 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	409	Shared Neighborhood Hits	13
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

TGON2_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.026764 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	1037	Shared Neighborhood Hits	34
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

WIRE_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.034745 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	329	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ZN292_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.019114 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	918	Shared Neighborhood Hits	12
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

AF17_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.023345 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	230	Shared Neighborhood Hits	16
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AKAP8_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.017821 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

HXB5_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.004561 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

LPIN2_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.029884 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

MARK2_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.003822 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	1018	Shared Neighborhood Hits	22
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

MINT_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.019472 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	1514	Shared Neighborhood Hits	35
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MRCKB_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.003373 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	2239	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYC_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.014916 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

PALB2_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.020955 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PRG4_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.018287 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	764	Shared Neighborhood Hits	22
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RABE1_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.013957 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	1104	Shared Neighborhood Hits	16
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

S4A4_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.017873 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6R1, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50	Gene names	SLC4A4, NBC, NBC1, NBCE1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1).

S4A4_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.017983 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O88343, Q3USE4, Q8BUG0, Q8QZR9, Q9R1C4	Gene names	Slc4a4, Nbc1, Nbce1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4).

SCEL_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.020014 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

TCF20_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.021204 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	323	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

CA106_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.036775 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

FR1OP_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.020204 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	O95684, Q49AI0, Q5R3F6, Q96EW1	Gene names	FGFR1OP, FOP
Domain Architecture	No domain graphic available
Description	FGFR1 oncogene partner.

GTF2I_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.016279 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

LR37B_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.011914 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	392	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

NFH_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.013500 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	2247	Shared Neighborhood Hits	41
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DSPP_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.018456 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	491	Shared Neighborhood Hits	15
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GNDS_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.009935 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

JHD1B_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.008283 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

KINH_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.008310 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	1231	Shared Neighborhood Hits	14
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

LPIN3_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.023826 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

MUCDL_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.011905 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	461	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCOR2_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.040540 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	790	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PHF14_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.017502 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PRR12_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.021945 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	460	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SRRM2_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.026021 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	1296	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ASTL_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.010978 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	252	Shared Neighborhood Hits	10
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BORG5_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.014532 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q91W92, Q9D8M1	Gene names	Cdc42ep1, Borg5, Cep1
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5).

CT077_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.010612 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

DCP1A_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.015054 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

GA2L1_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.009783 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GDIS_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.009384 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q61599, Q3TEB3	Gene names	Arhgdib, Gdid4
Domain Architecture
Description	Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Rho-GDI beta) (D4).

HIF1A_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.005868 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

LPIN2_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.022968 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	Q99PI5, Q8C357, Q8C7I8, Q8CC85, Q8CHR7	Gene names	Lpin2
Domain Architecture
Description	Lipin-2.

MAML1_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.013682 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MYO9B_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.004049 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	641	Shared Neighborhood Hits	16
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

STK10_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.003025 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	2132	Shared Neighborhood Hits	31
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

T22D2_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.019045 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	250	Shared Neighborhood Hits	12
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

GCN1L_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.057858 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

Hits sorted by NC score

PP4R1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_HUMAN
NC score	0.978480 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4RL_HUMAN
NC score	0.950741 (rank : 3)	θ value	3.88293e-136 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

2AAA_MOUSE
NC score	0.455110 (rank : 4)	θ value	6.00763e-12 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAA_HUMAN
NC score	0.454289 (rank : 5)	θ value	6.00763e-12 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAB_MOUSE
NC score	0.437551 (rank : 6)	θ value	3.89403e-11 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_HUMAN
NC score	0.434015 (rank : 7)	θ value	5.08577e-11 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

CI040_MOUSE
NC score	0.092467 (rank : 8)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

CI040_HUMAN
NC score	0.092027 (rank : 9)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IXQ3, Q9NWD3	Gene names	C9orf40
Domain Architecture	No domain graphic available
Description	Protein C9orf40.

NTKL_HUMAN
NC score	0.085865 (rank : 10)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

PI3R4_HUMAN
NC score	0.081974 (rank : 11)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

NOB1_MOUSE
NC score	0.081432 (rank : 12)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BW10, Q7TPR3, Q9CRD7	Gene names	Nob1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1.

PI3R4_MOUSE
NC score	0.080079 (rank : 13)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	535	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

HEMGN_MOUSE
NC score	0.078610 (rank : 14)	θ value	0.0252991 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

NOB1_HUMAN
NC score	0.076009 (rank : 15)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULX3, Q7L6B7, Q7M4M4, Q7Z4B5, Q9NWB0	Gene names	NOB1, ART4, NOB1P, PSMD8BP1
Domain Architecture	No domain graphic available
Description	RNA-binding protein NOB1 (Protein ART-4) (Phosphorylation regulatory protein HP-10).

NTKL_MOUSE
NC score	0.071445 (rank : 16)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

GCN1L_HUMAN
NC score	0.057858 (rank : 17)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

NCOR2_HUMAN
NC score	0.056671 (rank : 18)	θ value	0.00869519 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	870	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CA106_MOUSE
NC score	0.054288 (rank : 19)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

PABP2_HUMAN
NC score	0.044621 (rank : 20)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

RAD52_MOUSE
NC score	0.044338 (rank : 21)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P43352	Gene names	Rad52
Domain Architecture
Description	DNA repair protein RAD52 homolog.

WIRE_MOUSE
NC score	0.040575 (rank : 22)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	310	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

NCOR2_MOUSE
NC score	0.040540 (rank : 23)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	790	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

SET1A_HUMAN
NC score	0.037568 (rank : 24)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

CA106_HUMAN
NC score	0.036775 (rank : 25)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

SRRM2_MOUSE
NC score	0.035521 (rank : 26)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	1470	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PABP2_MOUSE
NC score	0.035036 (rank : 27)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

WIRE_HUMAN
NC score	0.034745 (rank : 28)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	329	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

NCOA6_MOUSE
NC score	0.034616 (rank : 29)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	1076	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOA6_HUMAN
NC score	0.032610 (rank : 30)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	1202	Shared Neighborhood Hits	31
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MAP9_HUMAN
NC score	0.031233 (rank : 31)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	518	Shared Neighborhood Hits	13
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MUC1_MOUSE
NC score	0.030374 (rank : 32)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	388	Shared Neighborhood Hits	19
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

AZI1_MOUSE
NC score	0.030173 (rank : 33)	θ value	0.0193708 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	990	Shared Neighborhood Hits	17
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

ATX7_HUMAN
NC score	0.030099 (rank : 34)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

IWS1_HUMAN
NC score	0.029915 (rank : 35)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	1241	Shared Neighborhood Hits	32
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LPIN2_HUMAN
NC score	0.029884 (rank : 36)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

MAP4_MOUSE
NC score	0.028738 (rank : 37)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SRBS1_HUMAN
NC score	0.027927 (rank : 38)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	396	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ING3_MOUSE
NC score	0.027349 (rank : 39)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_HUMAN
NC score	0.026976 (rank : 40)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

TGON2_HUMAN
NC score	0.026764 (rank : 41)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	1037	Shared Neighborhood Hits	34
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SRRM2_HUMAN
NC score	0.026021 (rank : 42)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	1296	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BRPF1_HUMAN
NC score	0.025746 (rank : 43)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	259	Shared Neighborhood Hits	12
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

LPIN3_HUMAN
NC score	0.023826 (rank : 44)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

MYCD_HUMAN
NC score	0.023788 (rank : 45)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

MILK2_HUMAN
NC score	0.023683 (rank : 46)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	457	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

EFS_MOUSE
NC score	0.023655 (rank : 47)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	389	Shared Neighborhood Hits	11
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

AF17_HUMAN
NC score	0.023345 (rank : 48)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	230	Shared Neighborhood Hits	16
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

LPIN2_MOUSE
NC score	0.022968 (rank : 49)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	Q99PI5, Q8C357, Q8C7I8, Q8CC85, Q8CHR7	Gene names	Lpin2
Domain Architecture
Description	Lipin-2.

SRBS1_MOUSE
NC score	0.022638 (rank : 50)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	409	Shared Neighborhood Hits	13
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PRR12_HUMAN
NC score	0.021945 (rank : 51)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	460	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

TCF20_HUMAN
NC score	0.021204 (rank : 52)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	323	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

PALB2_MOUSE
NC score	0.020955 (rank : 53)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

LAP2_HUMAN
NC score	0.020408 (rank : 54)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	499	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

FR1OP_HUMAN
NC score	0.020204 (rank : 55)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	O95684, Q49AI0, Q5R3F6, Q96EW1	Gene names	FGFR1OP, FOP
Domain Architecture	No domain graphic available
Description	FGFR1 oncogene partner.

SCEL_MOUSE
NC score	0.020014 (rank : 56)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

MINT_MOUSE
NC score	0.019472 (rank : 57)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	1514	Shared Neighborhood Hits	35
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ZN292_HUMAN
NC score	0.019114 (rank : 58)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	918	Shared Neighborhood Hits	12
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

T22D2_HUMAN
NC score	0.019045 (rank : 59)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	250	Shared Neighborhood Hits	12
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

DSPP_MOUSE
NC score	0.018456 (rank : 60)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	491	Shared Neighborhood Hits	15
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PRG4_HUMAN
NC score	0.018287 (rank : 61)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	764	Shared Neighborhood Hits	22
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

S4A4_MOUSE
NC score	0.017983 (rank : 62)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O88343, Q3USE4, Q8BUG0, Q8QZR9, Q9R1C4	Gene names	Slc4a4, Nbc1, Nbce1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4).

S4A4_HUMAN
NC score	0.017873 (rank : 63)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6R1, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50	Gene names	SLC4A4, NBC, NBC1, NBCE1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1).

AKAP8_MOUSE
NC score	0.017821 (rank : 64)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

PHF14_HUMAN
NC score	0.017502 (rank : 65)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

HRBL_HUMAN
NC score	0.017386 (rank : 66)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ADDB_HUMAN
NC score	0.017177 (rank : 67)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

GTF2I_MOUSE
NC score	0.016279 (rank : 68)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

ATBF1_MOUSE
NC score	0.015918 (rank : 69)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	1841	Shared Neighborhood Hits	29
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DCP1A_MOUSE
NC score	0.015054 (rank : 70)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

MYC_HUMAN
NC score	0.014916 (rank : 71)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

BORG5_MOUSE
NC score	0.014532 (rank : 72)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q91W92, Q9D8M1	Gene names	Cdc42ep1, Borg5, Cep1
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5).

RABE1_HUMAN
NC score	0.013957 (rank : 73)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	1104	Shared Neighborhood Hits	16
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

MAML1_HUMAN
NC score	0.013682 (rank : 74)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

NFH_MOUSE
NC score	0.013500 (rank : 75)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	2247	Shared Neighborhood Hits	41
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

FGD5_HUMAN
NC score	0.013090 (rank : 76)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

LR37B_HUMAN
NC score	0.011914 (rank : 77)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	392	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MUCDL_MOUSE
NC score	0.011905 (rank : 78)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	461	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ASTL_HUMAN
NC score	0.010978 (rank : 79)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	252	Shared Neighborhood Hits	10
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

KI13B_HUMAN
NC score	0.010703 (rank : 80)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	492	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

CT077_HUMAN
NC score	0.010612 (rank : 81)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

GNDS_HUMAN
NC score	0.009935 (rank : 82)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

ROBO1_HUMAN
NC score	0.009926 (rank : 83)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	529	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

GA2L1_MOUSE
NC score	0.009783 (rank : 84)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

CD2L1_MOUSE
NC score	0.009597 (rank : 85)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	1463	Shared Neighborhood Hits	16
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

GDIS_MOUSE
NC score	0.009384 (rank : 86)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q61599, Q3TEB3	Gene names	Arhgdib, Gdid4
Domain Architecture
Description	Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Rho-GDI beta) (D4).

KINH_HUMAN
NC score	0.008310 (rank : 87)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	1231	Shared Neighborhood Hits	14
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

JHD1B_HUMAN
NC score	0.008283 (rank : 88)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

RLF_HUMAN
NC score	0.008125 (rank : 89)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	775	Shared Neighborhood Hits	7
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

HIF1A_HUMAN
NC score	0.005868 (rank : 90)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HXB5_HUMAN
NC score	0.004561 (rank : 91)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

MYO9B_HUMAN
NC score	0.004049 (rank : 92)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	641	Shared Neighborhood Hits	16
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MARK2_MOUSE
NC score	0.003822 (rank : 93)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	1018	Shared Neighborhood Hits	22
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

MRCKB_HUMAN
NC score	0.003373 (rank : 94)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	2239	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

STK10_MOUSE
NC score	0.003025 (rank : 95)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	2132	Shared Neighborhood Hits	31
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).