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Network neighborhood for query Sequence : AKAP8_MOUSE

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AKAP8_MOUSE
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AKAP8_HUMAN
θ value	0 (rank : 1)	NC score	0.958300 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	166	Shared Neighborhood Hits	35
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

AKAP8_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

AKP8L_MOUSE
θ value	4.10295e-61 (rank : 3)	NC score	0.869549 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

AKP8L_HUMAN
θ value	2.03627e-60 (rank : 4)	NC score	0.875568 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

ZN326_MOUSE
θ value	1.08979e-29 (rank : 5)	NC score	0.726808 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

ZN326_HUMAN
θ value	1.33217e-27 (rank : 6)	NC score	0.730776 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

PHF10_MOUSE
θ value	0.0431538 (rank : 7)	NC score	0.062573 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF10_HUMAN
θ value	0.0563607 (rank : 8)	NC score	0.061580 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

RIF1_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.057403 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	315	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

A4_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.043847 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

CENPE_HUMAN
θ value	0.47712 (rank : 11)	NC score	0.017718 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	2060	Shared Neighborhood Hits	19
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

FKBP3_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.031500 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q00688, Q14317	Gene names	FKBP3, FKBP25
Domain Architecture
Description	FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin- selective 25 kDa immunophilin).

ROA2_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.046126 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P22626, P22627	Gene names	HNRPA2B1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP B1).

ROA2_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.041372 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	O88569	Gene names	Hnrpa2b1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP B1).

TB182_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.062367 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

ATBF1_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.019889 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	1841	Shared Neighborhood Hits	25
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

IFT81_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.016861 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	959	Shared Neighborhood Hits	13
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

MPP10_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.050919 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	306	Shared Neighborhood Hits	9
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

TMC2_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.024693 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

ZN132_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.004804 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	752	Shared Neighborhood Hits	12
SwissProt Accessions	P52740	Gene names	ZNF132
Domain Architecture	No domain graphic available
Description	Zinc finger protein 132.

GAK_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.005774 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	1028	Shared Neighborhood Hits	4
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

ITF2_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.029821 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

RBM6_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.045001 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	221	Shared Neighborhood Hits	6
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

YES_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.001680 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	1059	Shared Neighborhood Hits	5
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ITF2_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.029371 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

NKX22_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.015786 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	O95096	Gene names	NKX2-2, NKX2.2, NKX2B
Domain Architecture
Description	Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B).

RAD50_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.015919 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	1366	Shared Neighborhood Hits	20
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

ZFA_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.010462 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	746	Shared Neighborhood Hits	12
SwissProt Accessions	P23607	Gene names	Zfa
Domain Architecture
Description	Zinc finger autosomal protein.

CCD21_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.017277 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

DPOLA_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.030783 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

TNNT3_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.038587 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	317	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

DPOLA_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.030000 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

MAP2_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.018503 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	348	Shared Neighborhood Hits	8
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

NF2L2_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.026898 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

PPIG_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.016047 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	670	Shared Neighborhood Hits	15
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

ZFY_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.010230 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	752	Shared Neighborhood Hits	12
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.

AMPH_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.015847 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANKR2_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.007046 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	312	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ILF3_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.047528 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	68	Shared Neighborhood Hits	5
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

PP4R1_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.017821 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

RAD50_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.014994 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	1317	Shared Neighborhood Hits	18
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CS029_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.018967 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

PEF1_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.011310 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

ROA0_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.041706 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	Q13151	Gene names	HNRPA0
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0).

VKGC_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.036523 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P38435, Q14415, Q6GU45	Gene names	GGCX, GC
Domain Architecture
Description	Vitamin K-dependent gamma-carboxylase (EC 6.4.-.-) (Gamma-glutamyl carboxylase) (Vitamin K gamma glutamyl carboxylase).

VKGC_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.041311 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYC7, Q3UXN5, Q8CCB3	Gene names	Ggcx
Domain Architecture
Description	Vitamin K-dependent gamma-carboxylase (EC 6.4.-.-) (Gamma-glutamyl carboxylase) (Vitamin K gamma glutamyl carboxylase).

Z3H7A_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.024360 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

ZFX_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.009631 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	751	Shared Neighborhood Hits	14
SwissProt Accessions	P17010, O43668, Q8WYJ8	Gene names	ZFX
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFX_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.010046 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	748	Shared Neighborhood Hits	14
SwissProt Accessions	P17012, P17011	Gene names	Zfx
Domain Architecture
Description	Zinc finger X-chromosomal protein.

AN32B_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.008084 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	243	Shared Neighborhood Hits	2
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

ANKR2_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.006097 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	321	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

BMS1_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.019777 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

CNRG_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.017079 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P09174	Gene names	Pde6g, Pdeg
Domain Architecture
Description	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase gamma-subunit (EC 3.1.4.17) (GMP-PDE gamma).

FUS_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.044456 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

HNRPD_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.027256 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	221	Shared Neighborhood Hits	8
SwissProt Accessions	Q14103, Q01858, Q14100, Q14101, Q14102	Gene names	HNRPD, AUF1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

HNRPD_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.027300 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	220	Shared Neighborhood Hits	8
SwissProt Accessions	Q60668, Q60667, Q80ZJ0, Q91X94	Gene names	Hnrpd, Auf1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

INT1_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.021765 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N201, Q6NT70, Q6UX74, Q8WV40, Q96D36, Q9NTD1, Q9P2A8, Q9Y3W8	Gene names	INTS1, KIAA1440
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

INT1_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.021736 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P4S8, Q80UQ7, Q91Z01, Q9CTF7	Gene names	Ints1
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

NF2L2_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.018652 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	183	Shared Neighborhood Hits	6
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

NNP1_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.027114 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

PROX1_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.013783 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

RABE1_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.010175 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	1104	Shared Neighborhood Hits	16
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

ROA3_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.044401 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	199	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BG05, Q8BHF8	Gene names	Hnrpa3, Hnrnpa3
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3).

TSYL1_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.010243 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

ZN687_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.005353 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	1244	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CCD11_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.013914 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	822	Shared Neighborhood Hits	15
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

COE4_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.006797 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4J2, Q8K4J1, Q8K4J3, Q8K4J4, Q8K4J5	Gene names	Ebf4, Coe4
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

GOGA4_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.009260 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	1939	Shared Neighborhood Hits	21
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MY18A_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.011753 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	1929	Shared Neighborhood Hits	21
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NKX22_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.008206 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	336	Shared Neighborhood Hits	4
SwissProt Accessions	P42586	Gene names	Nkx2-2, Nkx-2.2, Nkx2b
Domain Architecture
Description	Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B).

RLF_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.005279 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	775	Shared Neighborhood Hits	10
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

RNF41_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.011760 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.011783 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

STK10_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.001962 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	1921	Shared Neighborhood Hits	18
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TSH1_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.014360 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	558	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

TSH1_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.014249 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	675	Shared Neighborhood Hits	11
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

ERIC1_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.059206 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	364	Shared Neighborhood Hits	11
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

Hits sorted by NC score

AKAP8_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

AKAP8_HUMAN
NC score	0.958300 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	166	Shared Neighborhood Hits	35
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

AKP8L_HUMAN
NC score	0.875568 (rank : 3)	θ value	2.03627e-60 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

AKP8L_MOUSE
NC score	0.869549 (rank : 4)	θ value	4.10295e-61 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

ZN326_HUMAN
NC score	0.730776 (rank : 5)	θ value	1.33217e-27 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

ZN326_MOUSE
NC score	0.726808 (rank : 6)	θ value	1.08979e-29 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

PHF10_MOUSE
NC score	0.062573 (rank : 7)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

TB182_HUMAN
NC score	0.062367 (rank : 8)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

PHF10_HUMAN
NC score	0.061580 (rank : 9)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

ERIC1_HUMAN
NC score	0.059206 (rank : 10)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	364	Shared Neighborhood Hits	11
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

RIF1_MOUSE
NC score	0.057403 (rank : 11)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	315	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

MPP10_HUMAN
NC score	0.050919 (rank : 12)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	306	Shared Neighborhood Hits	9
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

ILF3_HUMAN
NC score	0.047528 (rank : 13)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	68	Shared Neighborhood Hits	5
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

ROA2_HUMAN
NC score	0.046126 (rank : 14)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	P22626, P22627	Gene names	HNRPA2B1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP B1).

RBM6_HUMAN
NC score	0.045001 (rank : 15)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	221	Shared Neighborhood Hits	6
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

FUS_MOUSE
NC score	0.044456 (rank : 16)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

ROA3_MOUSE
NC score	0.044401 (rank : 17)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	199	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BG05, Q8BHF8	Gene names	Hnrpa3, Hnrnpa3
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3).

A4_HUMAN
NC score	0.043847 (rank : 18)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

ROA0_HUMAN
NC score	0.041706 (rank : 19)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	Q13151	Gene names	HNRPA0
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0).

ROA2_MOUSE
NC score	0.041372 (rank : 20)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	O88569	Gene names	Hnrpa2b1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP B1).

VKGC_MOUSE
NC score	0.041311 (rank : 21)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYC7, Q3UXN5, Q8CCB3	Gene names	Ggcx
Domain Architecture
Description	Vitamin K-dependent gamma-carboxylase (EC 6.4.-.-) (Gamma-glutamyl carboxylase) (Vitamin K gamma glutamyl carboxylase).

TNNT3_MOUSE
NC score	0.038587 (rank : 22)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	317	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

VKGC_HUMAN
NC score	0.036523 (rank : 23)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P38435, Q14415, Q6GU45	Gene names	GGCX, GC
Domain Architecture
Description	Vitamin K-dependent gamma-carboxylase (EC 6.4.-.-) (Gamma-glutamyl carboxylase) (Vitamin K gamma glutamyl carboxylase).

FKBP3_HUMAN
NC score	0.031500 (rank : 24)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q00688, Q14317	Gene names	FKBP3, FKBP25
Domain Architecture
Description	FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin- selective 25 kDa immunophilin).

DPOLA_MOUSE
NC score	0.030783 (rank : 25)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOLA_HUMAN
NC score	0.030000 (rank : 26)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

ITF2_HUMAN
NC score	0.029821 (rank : 27)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
NC score	0.029371 (rank : 28)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

HNRPD_MOUSE
NC score	0.027300 (rank : 29)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	220	Shared Neighborhood Hits	8
SwissProt Accessions	Q60668, Q60667, Q80ZJ0, Q91X94	Gene names	Hnrpd, Auf1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

HNRPD_HUMAN
NC score	0.027256 (rank : 30)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	221	Shared Neighborhood Hits	8
SwissProt Accessions	Q14103, Q01858, Q14100, Q14101, Q14102	Gene names	HNRPD, AUF1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

NNP1_MOUSE
NC score	0.027114 (rank : 31)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

NF2L2_HUMAN
NC score	0.026898 (rank : 32)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

TMC2_HUMAN
NC score	0.024693 (rank : 33)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

Z3H7A_HUMAN
NC score	0.024360 (rank : 34)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

INT1_HUMAN
NC score	0.021765 (rank : 35)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N201, Q6NT70, Q6UX74, Q8WV40, Q96D36, Q9NTD1, Q9P2A8, Q9Y3W8	Gene names	INTS1, KIAA1440
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

INT1_MOUSE
NC score	0.021736 (rank : 36)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P4S8, Q80UQ7, Q91Z01, Q9CTF7	Gene names	Ints1
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

ATBF1_MOUSE
NC score	0.019889 (rank : 37)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	1841	Shared Neighborhood Hits	25
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BMS1_HUMAN
NC score	0.019777 (rank : 38)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

CS029_HUMAN
NC score	0.018967 (rank : 39)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

NF2L2_MOUSE
NC score	0.018652 (rank : 40)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	183	Shared Neighborhood Hits	6
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

MAP2_HUMAN
NC score	0.018503 (rank : 41)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	348	Shared Neighborhood Hits	8
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

PP4R1_MOUSE
NC score	0.017821 (rank : 42)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

CENPE_HUMAN
NC score	0.017718 (rank : 43)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	2060	Shared Neighborhood Hits	19
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CCD21_MOUSE
NC score	0.017277 (rank : 44)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CNRG_MOUSE
NC score	0.017079 (rank : 45)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P09174	Gene names	Pde6g, Pdeg
Domain Architecture
Description	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase gamma-subunit (EC 3.1.4.17) (GMP-PDE gamma).

IFT81_MOUSE
NC score	0.016861 (rank : 46)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	959	Shared Neighborhood Hits	13
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

PPIG_HUMAN
NC score	0.016047 (rank : 47)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	670	Shared Neighborhood Hits	15
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RAD50_MOUSE
NC score	0.015919 (rank : 48)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	1366	Shared Neighborhood Hits	20
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

AMPH_MOUSE
NC score	0.015847 (rank : 49)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

NKX22_HUMAN
NC score	0.015786 (rank : 50)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	O95096	Gene names	NKX2-2, NKX2.2, NKX2B
Domain Architecture
Description	Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B).

RAD50_HUMAN
NC score	0.014994 (rank : 51)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	1317	Shared Neighborhood Hits	18
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

TSH1_HUMAN
NC score	0.014360 (rank : 52)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	558	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

TSH1_MOUSE
NC score	0.014249 (rank : 53)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	675	Shared Neighborhood Hits	11
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

CCD11_HUMAN
NC score	0.013914 (rank : 54)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	822	Shared Neighborhood Hits	15
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

PROX1_MOUSE
NC score	0.013783 (rank : 55)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

RNF41_MOUSE
NC score	0.011783 (rank : 56)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.011760 (rank : 57)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

MY18A_HUMAN
NC score	0.011753 (rank : 58)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	1929	Shared Neighborhood Hits	21
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PEF1_HUMAN
NC score	0.011310 (rank : 59)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

ZFA_MOUSE
NC score	0.010462 (rank : 60)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	746	Shared Neighborhood Hits	12
SwissProt Accessions	P23607	Gene names	Zfa
Domain Architecture
Description	Zinc finger autosomal protein.

TSYL1_MOUSE
NC score	0.010243 (rank : 61)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

ZFY_HUMAN
NC score	0.010230 (rank : 62)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	752	Shared Neighborhood Hits	12
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.

RABE1_HUMAN
NC score	0.010175 (rank : 63)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	1104	Shared Neighborhood Hits	16
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

ZFX_MOUSE
NC score	0.010046 (rank : 64)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	748	Shared Neighborhood Hits	14
SwissProt Accessions	P17012, P17011	Gene names	Zfx
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFX_HUMAN
NC score	0.009631 (rank : 65)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	751	Shared Neighborhood Hits	14
SwissProt Accessions	P17010, O43668, Q8WYJ8	Gene names	ZFX
Domain Architecture
Description	Zinc finger X-chromosomal protein.

GOGA4_MOUSE
NC score	0.009260 (rank : 66)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	1939	Shared Neighborhood Hits	21
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

NKX22_MOUSE
NC score	0.008206 (rank : 67)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	336	Shared Neighborhood Hits	4
SwissProt Accessions	P42586	Gene names	Nkx2-2, Nkx-2.2, Nkx2b
Domain Architecture
Description	Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B).

AN32B_HUMAN
NC score	0.008084 (rank : 68)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	243	Shared Neighborhood Hits	2
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

ANKR2_MOUSE
NC score	0.007046 (rank : 69)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	312	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

COE4_MOUSE
NC score	0.006797 (rank : 70)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4J2, Q8K4J1, Q8K4J3, Q8K4J4, Q8K4J5	Gene names	Ebf4, Coe4
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

ANKR2_HUMAN
NC score	0.006097 (rank : 71)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	321	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

GAK_HUMAN
NC score	0.005774 (rank : 72)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	1028	Shared Neighborhood Hits	4
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

ZN687_HUMAN
NC score	0.005353 (rank : 73)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	1244	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

RLF_HUMAN
NC score	0.005279 (rank : 74)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	775	Shared Neighborhood Hits	10
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

ZN132_HUMAN
NC score	0.004804 (rank : 75)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	752	Shared Neighborhood Hits	12
SwissProt Accessions	P52740	Gene names	ZNF132
Domain Architecture	No domain graphic available
Description	Zinc finger protein 132.

STK10_HUMAN
NC score	0.001962 (rank : 76)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	1921	Shared Neighborhood Hits	18
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

YES_HUMAN
NC score	0.001680 (rank : 77)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	1059	Shared Neighborhood Hits	5
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).