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Network neighborhood for query Sequence : ITF2_MOUSE

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ITF2_MOUSE
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HTF4_HUMAN
θ value	0 (rank : 1)	NC score	0.964236 (rank : 4)
Query Neighborhood Hits	154	Target Neighborhood Hits	152	Shared Neighborhood Hits	68
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

HTF4_MOUSE
θ value	0 (rank : 2)	NC score	0.965029 (rank : 3)
Query Neighborhood Hits	154	Target Neighborhood Hits	153	Shared Neighborhood Hits	70
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

ITF2_HUMAN
θ value	0 (rank : 3)	NC score	0.991501 (rank : 2)
Query Neighborhood Hits	154	Target Neighborhood Hits	168	Shared Neighborhood Hits	130
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	154
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

TFE2_HUMAN
θ value	9.54178e-143 (rank : 5)	NC score	0.947709 (rank : 6)
Query Neighborhood Hits	154	Target Neighborhood Hits	161	Shared Neighborhood Hits	58
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

TFE2_MOUSE
θ value	2.87963e-131 (rank : 6)	NC score	0.948114 (rank : 5)
Query Neighborhood Hits	154	Target Neighborhood Hits	118	Shared Neighborhood Hits	52
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

HORN_MOUSE
θ value	0.000270298 (rank : 7)	NC score	0.111609 (rank : 50)
Query Neighborhood Hits	154	Target Neighborhood Hits	218	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

HORN_HUMAN
θ value	0.000461057 (rank : 8)	NC score	0.118188 (rank : 48)
Query Neighborhood Hits	154	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

ATOH1_MOUSE
θ value	0.00509761 (rank : 9)	NC score	0.242530 (rank : 7)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

CDKL5_HUMAN
θ value	0.00509761 (rank : 10)	NC score	0.012767 (rank : 164)
Query Neighborhood Hits	154	Target Neighborhood Hits	967	Shared Neighborhood Hits	14
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

ATOH1_HUMAN
θ value	0.00665767 (rank : 11)	NC score	0.217867 (rank : 11)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

BHLH8_MOUSE
θ value	0.00869519 (rank : 12)	NC score	0.213351 (rank : 12)
Query Neighborhood Hits	154	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

CI039_HUMAN
θ value	0.0252991 (rank : 13)	NC score	0.029856 (rank : 116)
Query Neighborhood Hits	154	Target Neighborhood Hits	1171	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

POT15_HUMAN
θ value	0.0330416 (rank : 14)	NC score	0.029407 (rank : 119)
Query Neighborhood Hits	154	Target Neighborhood Hits	893	Shared Neighborhood Hits	28
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

EGR1_MOUSE
θ value	0.0431538 (rank : 15)	NC score	0.011908 (rank : 166)
Query Neighborhood Hits	154	Target Neighborhood Hits	816	Shared Neighborhood Hits	15
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

NDF2_HUMAN
θ value	0.0431538 (rank : 16)	NC score	0.196393 (rank : 17)
Query Neighborhood Hits	154	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	0.0431538 (rank : 17)	NC score	0.195595 (rank : 20)
Query Neighborhood Hits	154	Target Neighborhood Hits	111	Shared Neighborhood Hits	52
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

MYF5_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.224316 (rank : 10)
Query Neighborhood Hits	154	Target Neighborhood Hits	80	Shared Neighborhood Hits	45
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF5_MOUSE
θ value	0.0563607 (rank : 19)	NC score	0.227153 (rank : 8)
Query Neighborhood Hits	154	Target Neighborhood Hits	77	Shared Neighborhood Hits	45
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

BHLH8_HUMAN
θ value	0.0736092 (rank : 20)	NC score	0.190999 (rank : 22)
Query Neighborhood Hits	154	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

LRRF2_HUMAN
θ value	0.0736092 (rank : 21)	NC score	0.037276 (rank : 106)
Query Neighborhood Hits	154	Target Neighborhood Hits	791	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

TWST1_HUMAN
θ value	0.0736092 (rank : 22)	NC score	0.198529 (rank : 15)
Query Neighborhood Hits	154	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
θ value	0.0736092 (rank : 23)	NC score	0.198230 (rank : 16)
Query Neighborhood Hits	154	Target Neighborhood Hits	101	Shared Neighborhood Hits	49
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

FIGLA_MOUSE
θ value	0.0961366 (rank : 24)	NC score	0.225862 (rank : 9)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

HEN1_MOUSE
θ value	0.0961366 (rank : 25)	NC score	0.189129 (rank : 23)
Query Neighborhood Hits	154	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

MYOD1_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.205233 (rank : 14)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MYOD1_MOUSE
θ value	0.0961366 (rank : 27)	NC score	0.207157 (rank : 13)
Query Neighborhood Hits	154	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

NDF1_HUMAN
θ value	0.0961366 (rank : 28)	NC score	0.181028 (rank : 30)
Query Neighborhood Hits	154	Target Neighborhood Hits	186	Shared Neighborhood Hits	55
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF6_HUMAN
θ value	0.0961366 (rank : 29)	NC score	0.171079 (rank : 33)
Query Neighborhood Hits	154	Target Neighborhood Hits	91	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
θ value	0.0961366 (rank : 30)	NC score	0.171020 (rank : 34)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	45
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

PER2_MOUSE
θ value	0.0961366 (rank : 31)	NC score	0.029550 (rank : 118)
Query Neighborhood Hits	154	Target Neighborhood Hits	325	Shared Neighborhood Hits	11
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

DSPP_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.079417 (rank : 78)
Query Neighborhood Hits	154	Target Neighborhood Hits	645	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

EWS_HUMAN
θ value	0.125558 (rank : 33)	NC score	0.061101 (rank : 85)
Query Neighborhood Hits	154	Target Neighborhood Hits	249	Shared Neighborhood Hits	14
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

EWS_MOUSE
θ value	0.125558 (rank : 34)	NC score	0.060174 (rank : 86)
Query Neighborhood Hits	154	Target Neighborhood Hits	271	Shared Neighborhood Hits	15
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

HEN2_HUMAN
θ value	0.125558 (rank : 35)	NC score	0.188309 (rank : 24)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
θ value	0.125558 (rank : 36)	NC score	0.188094 (rank : 25)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

NDF1_MOUSE
θ value	0.125558 (rank : 37)	NC score	0.180764 (rank : 31)
Query Neighborhood Hits	154	Target Neighborhood Hits	209	Shared Neighborhood Hits	55
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

TB182_HUMAN
θ value	0.163984 (rank : 38)	NC score	0.080342 (rank : 76)
Query Neighborhood Hits	154	Target Neighborhood Hits	414	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TWST2_HUMAN
θ value	0.163984 (rank : 39)	NC score	0.195872 (rank : 19)
Query Neighborhood Hits	154	Target Neighborhood Hits	107	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
θ value	0.163984 (rank : 40)	NC score	0.196073 (rank : 18)
Query Neighborhood Hits	154	Target Neighborhood Hits	107	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

LEO1_HUMAN
θ value	0.21417 (rank : 41)	NC score	0.048590 (rank : 95)
Query Neighborhood Hits	154	Target Neighborhood Hits	958	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MLX_HUMAN
θ value	0.21417 (rank : 42)	NC score	0.055884 (rank : 90)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

NIPBL_HUMAN
θ value	0.21417 (rank : 43)	NC score	0.035563 (rank : 107)
Query Neighborhood Hits	154	Target Neighborhood Hits	1311	Shared Neighborhood Hits	46
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ANR21_HUMAN
θ value	0.279714 (rank : 44)	NC score	0.022555 (rank : 129)
Query Neighborhood Hits	154	Target Neighborhood Hits	864	Shared Neighborhood Hits	22
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

HEN1_HUMAN
θ value	0.279714 (rank : 45)	NC score	0.184607 (rank : 28)
Query Neighborhood Hits	154	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

MYCN_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.086380 (rank : 72)
Query Neighborhood Hits	154	Target Neighborhood Hits	127	Shared Neighborhood Hits	23
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYOG_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.193817 (rank : 21)
Query Neighborhood Hits	154	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.187803 (rank : 26)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

TAL1_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.170699 (rank : 35)
Query Neighborhood Hits	154	Target Neighborhood Hits	112	Shared Neighborhood Hits	54
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

TAL1_MOUSE
θ value	0.279714 (rank : 50)	NC score	0.171379 (rank : 32)
Query Neighborhood Hits	154	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

NDF4_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.185447 (rank : 27)
Query Neighborhood Hits	154	Target Neighborhood Hits	91	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

NDF4_MOUSE
θ value	0.365318 (rank : 52)	NC score	0.182700 (rank : 29)
Query Neighborhood Hits	154	Target Neighborhood Hits	105	Shared Neighborhood Hits	50
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

TTLL4_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.034459 (rank : 109)
Query Neighborhood Hits	154	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

CDSN_HUMAN
θ value	0.47712 (rank : 54)	NC score	0.052914 (rank : 91)
Query Neighborhood Hits	154	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q15517, O43509, Q5SQ85, Q5STD2, Q7LA70, Q7LA71, Q86Z04, Q8IZU4, Q8IZU5, Q8IZU6, Q8N5P3, Q95IF9, Q9NP52, Q9NPE0, Q9NPG5, Q9NRH4, Q9NRH5, Q9NRH6, Q9NRH7, Q9NRH8, Q9UBH8, Q9UIN6, Q9UIN7, Q9UIN8, Q9UIN9, Q9UIP0	Gene names	CDSN
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor (S protein).

UTY_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.031339 (rank : 114)
Query Neighborhood Hits	154	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	O14607, O14608	Gene names	UTY
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the Y chromosome).

ZN750_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.049020 (rank : 93)
Query Neighborhood Hits	154	Target Neighborhood Hits	183	Shared Neighborhood Hits	7
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

LEO1_MOUSE
θ value	0.62314 (rank : 57)	NC score	0.040870 (rank : 101)
Query Neighborhood Hits	154	Target Neighborhood Hits	946	Shared Neighborhood Hits	33
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LYL1_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.169635 (rank : 36)
Query Neighborhood Hits	154	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

MYCN_MOUSE
θ value	0.62314 (rank : 59)	NC score	0.079760 (rank : 77)
Query Neighborhood Hits	154	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

RMP_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.072511 (rank : 80)
Query Neighborhood Hits	154	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O94763	Gene names	RMP, C19orf2
Domain Architecture
Description	RNA polymerase II subunit 5-mediating protein (RPB5-mediating protein).

TTC1_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.020329 (rank : 135)
Query Neighborhood Hits	154	Target Neighborhood Hits	417	Shared Neighborhood Hits	15
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

CE152_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.024340 (rank : 125)
Query Neighborhood Hits	154	Target Neighborhood Hits	976	Shared Neighborhood Hits	16
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

GP179_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.023348 (rank : 127)
Query Neighborhood Hits	154	Target Neighborhood Hits	372	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

K0423_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.033317 (rank : 111)
Query Neighborhood Hits	154	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

CO4A2_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.017227 (rank : 145)
Query Neighborhood Hits	154	Target Neighborhood Hits	454	Shared Neighborhood Hits	15
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

EGR1_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.007959 (rank : 174)
Query Neighborhood Hits	154	Target Neighborhood Hits	788	Shared Neighborhood Hits	8
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

LYL1_MOUSE
θ value	1.06291 (rank : 67)	NC score	0.162929 (rank : 40)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

MUC1_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.032749 (rank : 112)
Query Neighborhood Hits	154	Target Neighborhood Hits	388	Shared Neighborhood Hits	16
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SRR35_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.018454 (rank : 141)
Query Neighborhood Hits	154	Target Neighborhood Hits	215	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXF0, Q8WW25	Gene names	SRRP35
Domain Architecture
Description	35 kDa SR repressor protein (SRrp35).

STK6_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.001678 (rank : 181)
Query Neighborhood Hits	154	Target Neighborhood Hits	916	Shared Neighborhood Hits	7
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).

ZFP37_MOUSE
θ value	1.06291 (rank : 71)	NC score	-0.000474 (rank : 182)
Query Neighborhood Hits	154	Target Neighborhood Hits	906	Shared Neighborhood Hits	16
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

BRD7_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.023650 (rank : 126)
Query Neighborhood Hits	154	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

CENPE_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.013088 (rank : 160)
Query Neighborhood Hits	154	Target Neighborhood Hits	2060	Shared Neighborhood Hits	37
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DAB2_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.037707 (rank : 104)
Query Neighborhood Hits	154	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

FIGLA_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.166378 (rank : 37)
Query Neighborhood Hits	154	Target Neighborhood Hits	108	Shared Neighborhood Hits	53
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MUSC_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.132539 (rank : 44)
Query Neighborhood Hits	154	Target Neighborhood Hits	78	Shared Neighborhood Hits	41
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

MUSC_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.133718 (rank : 43)
Query Neighborhood Hits	154	Target Neighborhood Hits	78	Shared Neighborhood Hits	41
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MYF6_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.165729 (rank : 39)
Query Neighborhood Hits	154	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.166227 (rank : 38)
Query Neighborhood Hits	154	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

AKAP8_MOUSE
θ value	1.81305 (rank : 80)	NC score	0.029371 (rank : 121)
Query Neighborhood Hits	154	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

BCAR1_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.030914 (rank : 115)
Query Neighborhood Hits	154	Target Neighborhood Hits	554	Shared Neighborhood Hits	11
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CHD9_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.019899 (rank : 137)
Query Neighborhood Hits	154	Target Neighborhood Hits	343	Shared Neighborhood Hits	22
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

DAB2_MOUSE
θ value	1.81305 (rank : 83)	NC score	0.037291 (rank : 105)
Query Neighborhood Hits	154	Target Neighborhood Hits	163	Shared Neighborhood Hits	12
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

HAND2_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.159127 (rank : 41)
Query Neighborhood Hits	154	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.159127 (rank : 42)
Query Neighborhood Hits	154	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

IRS1_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.033538 (rank : 110)
Query Neighborhood Hits	154	Target Neighborhood Hits	112	Shared Neighborhood Hits	10
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

MLX_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.048880 (rank : 94)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

RNPS1_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.041800 (rank : 97)
Query Neighborhood Hits	154	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	1.81305 (rank : 89)	NC score	0.041800 (rank : 98)
Query Neighborhood Hits	154	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

UBP4_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.008657 (rank : 173)
Query Neighborhood Hits	154	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

BHLH4_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.119596 (rank : 47)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

CO5A2_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.014890 (rank : 153)
Query Neighborhood Hits	154	Target Neighborhood Hits	760	Shared Neighborhood Hits	20
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

COIA1_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.020680 (rank : 132)
Query Neighborhood Hits	154	Target Neighborhood Hits	447	Shared Neighborhood Hits	14
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

NCOA6_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.038731 (rank : 103)
Query Neighborhood Hits	154	Target Neighborhood Hits	1076	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TCF20_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.029727 (rank : 117)
Query Neighborhood Hits	154	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TFE3_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.063160 (rank : 84)
Query Neighborhood Hits	154	Target Neighborhood Hits	190	Shared Neighborhood Hits	19
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

B3A3_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.010344 (rank : 171)
Query Neighborhood Hits	154	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

CHD9_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.017103 (rank : 147)
Query Neighborhood Hits	154	Target Neighborhood Hits	427	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CROP_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.058360 (rank : 88)
Query Neighborhood Hits	154	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CROP_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.057626 (rank : 89)
Query Neighborhood Hits	154	Target Neighborhood Hits	403	Shared Neighborhood Hits	18
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

ERC2_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.013625 (rank : 158)
Query Neighborhood Hits	154	Target Neighborhood Hits	1156	Shared Neighborhood Hits	25
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.013496 (rank : 159)
Query Neighborhood Hits	154	Target Neighborhood Hits	1166	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

FGD5_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.015310 (rank : 152)
Query Neighborhood Hits	154	Target Neighborhood Hits	235	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

HNF1B_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.020366 (rank : 134)
Query Neighborhood Hits	154	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	P35680	Gene names	TCF2, HNF1B
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2).

IRS1_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.047084 (rank : 96)
Query Neighborhood Hits	154	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

NAF1_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.012988 (rank : 162)
Query Neighborhood Hits	154	Target Neighborhood Hits	852	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NEDD4_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.007789 (rank : 175)
Query Neighborhood Hits	154	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

ANK2_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.012902 (rank : 163)
Query Neighborhood Hits	154	Target Neighborhood Hits	1615	Shared Neighborhood Hits	44
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BAZ2A_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.041319 (rank : 99)
Query Neighborhood Hits	154	Target Neighborhood Hits	744	Shared Neighborhood Hits	28
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BTBDC_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.028504 (rank : 122)
Query Neighborhood Hits	154	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

FBX24_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.040964 (rank : 100)
Query Neighborhood Hits	154	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D417	Gene names	Fbxo24, Fbx24
Domain Architecture	No domain graphic available
Description	F-box only protein 24.

INVS_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.019964 (rank : 136)
Query Neighborhood Hits	154	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

K1C9_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.007049 (rank : 176)
Query Neighborhood Hits	154	Target Neighborhood Hits	526	Shared Neighborhood Hits	15
SwissProt Accessions	P35527, O00109, Q14665	Gene names	KRT9
Domain Architecture
Description	Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9).

MATR3_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.025215 (rank : 123)
Query Neighborhood Hits	154	Target Neighborhood Hits	321	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MITF_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.040009 (rank : 102)
Query Neighborhood Hits	154	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

PRDM2_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.004908 (rank : 179)
Query Neighborhood Hits	154	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SH2D3_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.015963 (rank : 150)
Query Neighborhood Hits	154	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SNCAP_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.020849 (rank : 131)
Query Neighborhood Hits	154	Target Neighborhood Hits	313	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

WASIP_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.015555 (rank : 151)
Query Neighborhood Hits	154	Target Neighborhood Hits	458	Shared Neighborhood Hits	18
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BHLH4_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.107752 (rank : 55)
Query Neighborhood Hits	154	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

DMXL1_MOUSE
θ value	5.27518 (rank : 121)	NC score	0.010927 (rank : 170)
Query Neighborhood Hits	154	Target Neighborhood Hits	257	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

FILA_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.059080 (rank : 87)
Query Neighborhood Hits	154	Target Neighborhood Hits	685	Shared Neighborhood Hits	31
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GP115_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.006190 (rank : 177)
Query Neighborhood Hits	154	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

HUWE1_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.016457 (rank : 148)
Query Neighborhood Hits	154	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

MITF_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.035257 (rank : 108)
Query Neighborhood Hits	154	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

OLIG1_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.095819 (rank : 64)
Query Neighborhood Hits	154	Target Neighborhood Hits	85	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

PGCA_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.025204 (rank : 124)
Query Neighborhood Hits	154	Target Neighborhood Hits	821	Shared Neighborhood Hits	24
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SAKS1_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.019345 (rank : 140)
Query Neighborhood Hits	154	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

CBP_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.014266 (rank : 155)
Query Neighborhood Hits	154	Target Neighborhood Hits	1051	Shared Neighborhood Hits	27
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CDCP1_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.021957 (rank : 130)
Query Neighborhood Hits	154	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H5V8, Q49UB4, Q6NT71, Q6U9Y2, Q8WU91, Q96QU7, Q9H676, Q9H8C2	Gene names	CDCP1, TRASK
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (CD318 antigen).

CO1A1_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.013738 (rank : 157)
Query Neighborhood Hits	154	Target Neighborhood Hits	475	Shared Neighborhood Hits	15
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

F125A_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.018402 (rank : 142)
Query Neighborhood Hits	154	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q78HU3	Gene names	Fam125a
Domain Architecture	No domain graphic available
Description	Protein FAM125A.

HUWE1_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.016404 (rank : 149)
Query Neighborhood Hits	154	Target Neighborhood Hits	443	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

MCCA_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.011464 (rank : 168)
Query Neighborhood Hits	154	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RQ3, Q59ES4, Q9H959, Q9NS97	Gene names	MCCC1, MCCA
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

NAF1_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.011862 (rank : 167)
Query Neighborhood Hits	154	Target Neighborhood Hits	937	Shared Neighborhood Hits	17
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NCOA2_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.012552 (rank : 165)
Query Neighborhood Hits	154	Target Neighborhood Hits	281	Shared Neighborhood Hits	18
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

REN3B_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.029398 (rank : 120)
Query Neighborhood Hits	154	Target Neighborhood Hits	412	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

SRP72_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.031752 (rank : 113)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	O76094	Gene names	SRP72
Domain Architecture
Description	Signal recognition particle 72 kDa protein (SRP72).

BAZ2A_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.014502 (rank : 154)
Query Neighborhood Hits	154	Target Neighborhood Hits	780	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BRE1A_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.019347 (rank : 139)
Query Neighborhood Hits	154	Target Neighborhood Hits	1071	Shared Neighborhood Hits	26
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.020570 (rank : 133)
Query Neighborhood Hits	154	Target Neighborhood Hits	1025	Shared Neighborhood Hits	25
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BSN_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.011301 (rank : 169)
Query Neighborhood Hits	154	Target Neighborhood Hits	1537	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CAC1F_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.003901 (rank : 180)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CJ006_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.017120 (rank : 146)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P9P0, Q8C041, Q8C0J5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf6 homolog.

DJBP_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.013817 (rank : 156)
Query Neighborhood Hits	154	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

HCN4_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.005232 (rank : 178)
Query Neighborhood Hits	154	Target Neighborhood Hits	284	Shared Neighborhood Hits	9
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

IPP2_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.019755 (rank : 138)
Query Neighborhood Hits	154	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

NCOA6_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.017499 (rank : 143)
Query Neighborhood Hits	154	Target Neighborhood Hits	1202	Shared Neighborhood Hits	33
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PRRT1_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.023130 (rank : 128)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PTF1A_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.126805 (rank : 45)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

PTF1A_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.126246 (rank : 46)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

RAD50_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.017486 (rank : 144)
Query Neighborhood Hits	154	Target Neighborhood Hits	1366	Shared Neighborhood Hits	27
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RAPH1_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.009803 (rank : 172)
Query Neighborhood Hits	154	Target Neighborhood Hits	593	Shared Neighborhood Hits	16
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

TEX15_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.013073 (rank : 161)
Query Neighborhood Hits	154	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

ASCL1_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.080822 (rank : 75)
Query Neighborhood Hits	154	Target Neighborhood Hits	94	Shared Neighborhood Hits	45
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

ASCL1_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.081456 (rank : 73)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

ASCL2_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.098626 (rank : 60)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

ASCL2_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.081382 (rank : 74)
Query Neighborhood Hits	154	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

ASCL3_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.091461 (rank : 67)
Query Neighborhood Hits	154	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

ASCL3_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.094122 (rank : 65)
Query Neighborhood Hits	154	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

CDSN_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.051559 (rank : 92)
Query Neighborhood Hits	154	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

HAND1_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.096189 (rank : 63)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

HAND1_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.097066 (rank : 62)
Query Neighborhood Hits	154	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

NGN1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.108672 (rank : 53)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	44
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

NGN1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.112000 (rank : 49)
Query Neighborhood Hits	154	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

NGN2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.105254 (rank : 58)
Query Neighborhood Hits	154	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.105218 (rank : 59)
Query Neighborhood Hits	154	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NGN3_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.106054 (rank : 57)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

NGN3_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.106960 (rank : 56)
Query Neighborhood Hits	154	Target Neighborhood Hits	90	Shared Neighborhood Hits	43
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

OLIG1_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.071941 (rank : 81)
Query Neighborhood Hits	154	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

OLIG2_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.088244 (rank : 70)
Query Neighborhood Hits	154	Target Neighborhood Hits	84	Shared Neighborhood Hits	38
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG2_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.090341 (rank : 68)
Query Neighborhood Hits	154	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

OLIG3_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.069654 (rank : 83)
Query Neighborhood Hits	154	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

OLIG3_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.071333 (rank : 82)
Query Neighborhood Hits	154	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

SCX_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.109242 (rank : 52)
Query Neighborhood Hits	154	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

TAL2_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.108444 (rank : 54)
Query Neighborhood Hits	154	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

TAL2_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.109895 (rank : 51)
Query Neighborhood Hits	154	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

TCF15_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.093990 (rank : 66)
Query Neighborhood Hits	154	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

TCF15_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.098019 (rank : 61)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	42
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

TCF21_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.088628 (rank : 69)
Query Neighborhood Hits	154	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.088172 (rank : 71)
Query Neighborhood Hits	154	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TFAP4_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.079268 (rank : 79)
Query Neighborhood Hits	154	Target Neighborhood Hits	289	Shared Neighborhood Hits	50
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

Hits sorted by NC score

ITF2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	154
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

ITF2_HUMAN
NC score	0.991501 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	154	Target Neighborhood Hits	168	Shared Neighborhood Hits	130
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

HTF4_MOUSE
NC score	0.965029 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	154	Target Neighborhood Hits	153	Shared Neighborhood Hits	70
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

HTF4_HUMAN
NC score	0.964236 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	154	Target Neighborhood Hits	152	Shared Neighborhood Hits	68
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

TFE2_MOUSE
NC score	0.948114 (rank : 5)	θ value	2.87963e-131 (rank : 6)
Query Neighborhood Hits	154	Target Neighborhood Hits	118	Shared Neighborhood Hits	52
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

TFE2_HUMAN
NC score	0.947709 (rank : 6)	θ value	9.54178e-143 (rank : 5)
Query Neighborhood Hits	154	Target Neighborhood Hits	161	Shared Neighborhood Hits	58
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

ATOH1_MOUSE
NC score	0.242530 (rank : 7)	θ value	0.00509761 (rank : 9)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

MYF5_MOUSE
NC score	0.227153 (rank : 8)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	154	Target Neighborhood Hits	77	Shared Neighborhood Hits	45
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

FIGLA_MOUSE
NC score	0.225862 (rank : 9)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MYF5_HUMAN
NC score	0.224316 (rank : 10)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	154	Target Neighborhood Hits	80	Shared Neighborhood Hits	45
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

ATOH1_HUMAN
NC score	0.217867 (rank : 11)	θ value	0.00665767 (rank : 11)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

BHLH8_MOUSE
NC score	0.213351 (rank : 12)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	154	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MYOD1_MOUSE
NC score	0.207157 (rank : 13)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	154	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MYOD1_HUMAN
NC score	0.205233 (rank : 14)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

TWST1_HUMAN
NC score	0.198529 (rank : 15)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	154	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
NC score	0.198230 (rank : 16)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	154	Target Neighborhood Hits	101	Shared Neighborhood Hits	49
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

NDF2_HUMAN
NC score	0.196393 (rank : 17)	θ value	0.0431538 (rank : 16)
Query Neighborhood Hits	154	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

TWST2_MOUSE
NC score	0.196073 (rank : 18)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	154	Target Neighborhood Hits	107	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_HUMAN
NC score	0.195872 (rank : 19)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	154	Target Neighborhood Hits	107	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

NDF2_MOUSE
NC score	0.195595 (rank : 20)	θ value	0.0431538 (rank : 17)
Query Neighborhood Hits	154	Target Neighborhood Hits	111	Shared Neighborhood Hits	52
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

MYOG_HUMAN
NC score	0.193817 (rank : 21)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	154	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

BHLH8_HUMAN
NC score	0.190999 (rank : 22)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	154	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

HEN1_MOUSE
NC score	0.189129 (rank : 23)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	154	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
NC score	0.188309 (rank : 24)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
NC score	0.188094 (rank : 25)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

MYOG_MOUSE
NC score	0.187803 (rank : 26)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

NDF4_HUMAN
NC score	0.185447 (rank : 27)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	154	Target Neighborhood Hits	91	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

HEN1_HUMAN
NC score	0.184607 (rank : 28)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	154	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

NDF4_MOUSE
NC score	0.182700 (rank : 29)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	154	Target Neighborhood Hits	105	Shared Neighborhood Hits	50
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

NDF1_HUMAN
NC score	0.181028 (rank : 30)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	154	Target Neighborhood Hits	186	Shared Neighborhood Hits	55
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF1_MOUSE
NC score	0.180764 (rank : 31)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	154	Target Neighborhood Hits	209	Shared Neighborhood Hits	55
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

TAL1_MOUSE
NC score	0.171379 (rank : 32)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	154	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

NDF6_HUMAN
NC score	0.171079 (rank : 33)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	154	Target Neighborhood Hits	91	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
NC score	0.171020 (rank : 34)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	45
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

TAL1_HUMAN
NC score	0.170699 (rank : 35)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	154	Target Neighborhood Hits	112	Shared Neighborhood Hits	54
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

LYL1_HUMAN
NC score	0.169635 (rank : 36)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	154	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

FIGLA_HUMAN
NC score	0.166378 (rank : 37)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	154	Target Neighborhood Hits	108	Shared Neighborhood Hits	53
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MYF6_MOUSE
NC score	0.166227 (rank : 38)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	154	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

MYF6_HUMAN
NC score	0.165729 (rank : 39)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	154	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

LYL1_MOUSE
NC score	0.162929 (rank : 40)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

HAND2_HUMAN
NC score	0.159127 (rank : 41)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	154	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
NC score	0.159127 (rank : 42)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	154	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

MUSC_MOUSE
NC score	0.133718 (rank : 43)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	154	Target Neighborhood Hits	78	Shared Neighborhood Hits	41
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MUSC_HUMAN
NC score	0.132539 (rank : 44)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	154	Target Neighborhood Hits	78	Shared Neighborhood Hits	41
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

PTF1A_HUMAN
NC score	0.126805 (rank : 45)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

PTF1A_MOUSE
NC score	0.126246 (rank : 46)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

BHLH4_MOUSE
NC score	0.119596 (rank : 47)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

HORN_HUMAN
NC score	0.118188 (rank : 48)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	154	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

NGN1_MOUSE
NC score	0.112000 (rank : 49)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	154	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

HORN_MOUSE
NC score	0.111609 (rank : 50)	θ value	0.000270298 (rank : 7)
Query Neighborhood Hits	154	Target Neighborhood Hits	218	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

TAL2_MOUSE
NC score	0.109895 (rank : 51)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	154	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

SCX_MOUSE
NC score	0.109242 (rank : 52)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	154	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

NGN1_HUMAN
NC score	0.108672 (rank : 53)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	44
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

TAL2_HUMAN
NC score	0.108444 (rank : 54)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	154	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

BHLH4_HUMAN
NC score	0.107752 (rank : 55)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	154	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

NGN3_MOUSE
NC score	0.106960 (rank : 56)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	154	Target Neighborhood Hits	90	Shared Neighborhood Hits	43
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

NGN3_HUMAN
NC score	0.106054 (rank : 57)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

NGN2_HUMAN
NC score	0.105254 (rank : 58)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	154	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN2_MOUSE
NC score	0.105218 (rank : 59)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	154	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

ASCL2_HUMAN
NC score	0.098626 (rank : 60)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

TCF15_MOUSE
NC score	0.098019 (rank : 61)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	42
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

HAND1_MOUSE
NC score	0.097066 (rank : 62)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	154	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

HAND1_HUMAN
NC score	0.096189 (rank : 63)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

OLIG1_HUMAN
NC score	0.095819 (rank : 64)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	154	Target Neighborhood Hits	85	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

ASCL3_MOUSE
NC score	0.094122 (rank : 65)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	154	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

TCF15_HUMAN
NC score	0.093990 (rank : 66)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	154	Target Neighborhood Hits	79	Shared Neighborhood Hits	40
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

ASCL3_HUMAN
NC score	0.091461 (rank : 67)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	154	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

OLIG2_MOUSE
NC score	0.090341 (rank : 68)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	154	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

TCF21_HUMAN
NC score	0.088628 (rank : 69)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	154	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

OLIG2_HUMAN
NC score	0.088244 (rank : 70)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	154	Target Neighborhood Hits	84	Shared Neighborhood Hits	38
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

TCF21_MOUSE
NC score	0.088172 (rank : 71)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	154	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

MYCN_HUMAN
NC score	0.086380 (rank : 72)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	154	Target Neighborhood Hits	127	Shared Neighborhood Hits	23
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

ASCL1_MOUSE
NC score	0.081456 (rank : 73)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

ASCL2_MOUSE
NC score	0.081382 (rank : 74)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	154	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

ASCL1_HUMAN
NC score	0.080822 (rank : 75)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	154	Target Neighborhood Hits	94	Shared Neighborhood Hits	45
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

TB182_HUMAN
NC score	0.080342 (rank : 76)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	154	Target Neighborhood Hits	414	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

MYCN_MOUSE
NC score	0.079760 (rank : 77)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	154	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

DSPP_HUMAN
NC score	0.079417 (rank : 78)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	154	Target Neighborhood Hits	645	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TFAP4_HUMAN
NC score	0.079268 (rank : 79)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	154	Target Neighborhood Hits	289	Shared Neighborhood Hits	50
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

RMP_HUMAN
NC score	0.072511 (rank : 80)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	154	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O94763	Gene names	RMP, C19orf2
Domain Architecture
Description	RNA polymerase II subunit 5-mediating protein (RPB5-mediating protein).

OLIG1_MOUSE
NC score	0.071941 (rank : 81)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	154	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JKN5	Gene names	Olig1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte- specific bHLH transcription factor 1).

OLIG3_MOUSE
NC score	0.071333 (rank : 82)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	154	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

OLIG3_HUMAN
NC score	0.069654 (rank : 83)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	154	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q7RTU3, Q8N8Q0	Gene names	OLIG3, BHLHB7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Basic helix-loop- helix domain-containing class B protein 7).

TFE3_HUMAN
NC score	0.063160 (rank : 84)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	154	Target Neighborhood Hits	190	Shared Neighborhood Hits	19
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

EWS_HUMAN
NC score	0.061101 (rank : 85)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	154	Target Neighborhood Hits	249	Shared Neighborhood Hits	14
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

EWS_MOUSE
NC score	0.060174 (rank : 86)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	154	Target Neighborhood Hits	271	Shared Neighborhood Hits	15
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

FILA_HUMAN
NC score	0.059080 (rank : 87)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	154	Target Neighborhood Hits	685	Shared Neighborhood Hits	31
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

CROP_HUMAN
NC score	0.058360 (rank : 88)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	154	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CROP_MOUSE
NC score	0.057626 (rank : 89)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	154	Target Neighborhood Hits	403	Shared Neighborhood Hits	18
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

MLX_HUMAN
NC score	0.055884 (rank : 90)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	154	Target Neighborhood Hits	95	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

CDSN_HUMAN
NC score	0.052914 (rank : 91)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	154	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q15517, O43509, Q5SQ85, Q5STD2, Q7LA70, Q7LA71, Q86Z04, Q8IZU4, Q8IZU5, Q8IZU6, Q8N5P3, Q95IF9, Q9NP52, Q9NPE0, Q9NPG5, Q9NRH4, Q9NRH5, Q9NRH6, Q9NRH7, Q9NRH8, Q9UBH8, Q9UIN6, Q9UIN7, Q9UIN8, Q9UIN9, Q9UIP0	Gene names	CDSN
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor (S protein).

CDSN_MOUSE
NC score	0.051559 (rank : 92)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	154	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

ZN750_HUMAN
NC score	0.049020 (rank : 93)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	154	Target Neighborhood Hits	183	Shared Neighborhood Hits	7
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

MLX_MOUSE
NC score	0.048880 (rank : 94)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

LEO1_HUMAN
NC score	0.048590 (rank : 95)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	154	Target Neighborhood Hits	958	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

IRS1_HUMAN
NC score	0.047084 (rank : 96)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	154	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

RNPS1_HUMAN
NC score	0.041800 (rank : 97)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	154	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.041800 (rank : 98)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	154	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

BAZ2A_MOUSE
NC score	0.041319 (rank : 99)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	154	Target Neighborhood Hits	744	Shared Neighborhood Hits	28
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

FBX24_MOUSE
NC score	0.040964 (rank : 100)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	154	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D417	Gene names	Fbxo24, Fbx24
Domain Architecture	No domain graphic available
Description	F-box only protein 24.

LEO1_MOUSE
NC score	0.040870 (rank : 101)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	154	Target Neighborhood Hits	946	Shared Neighborhood Hits	33
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MITF_MOUSE
NC score	0.040009 (rank : 102)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	154	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

NCOA6_MOUSE
NC score	0.038731 (rank : 103)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	154	Target Neighborhood Hits	1076	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

DAB2_HUMAN
NC score	0.037707 (rank : 104)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	154	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DAB2_MOUSE
NC score	0.037291 (rank : 105)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	154	Target Neighborhood Hits	163	Shared Neighborhood Hits	12
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

LRRF2_HUMAN
NC score	0.037276 (rank : 106)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	154	Target Neighborhood Hits	791	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

NIPBL_HUMAN
NC score	0.035563 (rank : 107)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	154	Target Neighborhood Hits	1311	Shared Neighborhood Hits	46
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MITF_HUMAN
NC score	0.035257 (rank : 108)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	154	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TTLL4_HUMAN
NC score	0.034459 (rank : 109)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	154	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

IRS1_MOUSE
NC score	0.033538 (rank : 110)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	154	Target Neighborhood Hits	112	Shared Neighborhood Hits	10
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

K0423_MOUSE
NC score	0.033317 (rank : 111)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	154	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

MUC1_MOUSE
NC score	0.032749 (rank : 112)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	154	Target Neighborhood Hits	388	Shared Neighborhood Hits	16
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SRP72_HUMAN
NC score	0.031752 (rank : 113)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	O76094	Gene names	SRP72
Domain Architecture
Description	Signal recognition particle 72 kDa protein (SRP72).

UTY_HUMAN
NC score	0.031339 (rank : 114)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	154	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	O14607, O14608	Gene names	UTY
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the Y chromosome).

BCAR1_HUMAN
NC score	0.030914 (rank : 115)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	154	Target Neighborhood Hits	554	Shared Neighborhood Hits	11
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CI039_HUMAN
NC score	0.029856 (rank : 116)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	154	Target Neighborhood Hits	1171	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

TCF20_MOUSE
NC score	0.029727 (rank : 117)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	154	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

PER2_MOUSE
NC score	0.029550 (rank : 118)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	154	Target Neighborhood Hits	325	Shared Neighborhood Hits	11
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

POT15_HUMAN
NC score	0.029407 (rank : 119)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	154	Target Neighborhood Hits	893	Shared Neighborhood Hits	28
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

REN3B_HUMAN
NC score	0.029398 (rank : 120)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	154	Target Neighborhood Hits	412	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

AKAP8_MOUSE
NC score	0.029371 (rank : 121)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	154	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

BTBDC_HUMAN
NC score	0.028504 (rank : 122)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	154	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

MATR3_MOUSE
NC score	0.025215 (rank : 123)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	154	Target Neighborhood Hits	321	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

PGCA_HUMAN
NC score	0.025204 (rank : 124)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	154	Target Neighborhood Hits	821	Shared Neighborhood Hits	24
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CE152_HUMAN
NC score	0.024340 (rank : 125)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	154	Target Neighborhood Hits	976	Shared Neighborhood Hits	16
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

BRD7_HUMAN
NC score	0.023650 (rank : 126)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	154	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

GP179_HUMAN
NC score	0.023348 (rank : 127)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	154	Target Neighborhood Hits	372	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

PRRT1_MOUSE
NC score	0.023130 (rank : 128)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

ANR21_HUMAN
NC score	0.022555 (rank : 129)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	154	Target Neighborhood Hits	864	Shared Neighborhood Hits	22
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

CDCP1_HUMAN
NC score	0.021957 (rank : 130)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	154	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H5V8, Q49UB4, Q6NT71, Q6U9Y2, Q8WU91, Q96QU7, Q9H676, Q9H8C2	Gene names	CDCP1, TRASK
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (CD318 antigen).

SNCAP_HUMAN
NC score	0.020849 (rank : 131)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	154	Target Neighborhood Hits	313	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

COIA1_HUMAN
NC score	0.020680 (rank : 132)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	154	Target Neighborhood Hits	447	Shared Neighborhood Hits	14
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

BRE1A_MOUSE
NC score	0.020570 (rank : 133)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	154	Target Neighborhood Hits	1025	Shared Neighborhood Hits	25
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

HNF1B_HUMAN
NC score	0.020366 (rank : 134)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	154	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	P35680	Gene names	TCF2, HNF1B
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2).

TTC1_HUMAN
NC score	0.020329 (rank : 135)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	154	Target Neighborhood Hits	417	Shared Neighborhood Hits	15
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

INVS_HUMAN
NC score	0.019964 (rank : 136)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	154	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

CHD9_HUMAN
NC score	0.019899 (rank : 137)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	154	Target Neighborhood Hits	343	Shared Neighborhood Hits	22
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

IPP2_MOUSE
NC score	0.019755 (rank : 138)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	154	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

BRE1A_HUMAN
NC score	0.019347 (rank : 139)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	154	Target Neighborhood Hits	1071	Shared Neighborhood Hits	26
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

SAKS1_HUMAN
NC score	0.019345 (rank : 140)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	154	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

SRR35_HUMAN
NC score	0.018454 (rank : 141)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	154	Target Neighborhood Hits	215	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXF0, Q8WW25	Gene names	SRRP35
Domain Architecture
Description	35 kDa SR repressor protein (SRrp35).

F125A_MOUSE
NC score	0.018402 (rank : 142)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	154	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q78HU3	Gene names	Fam125a
Domain Architecture	No domain graphic available
Description	Protein FAM125A.

NCOA6_HUMAN
NC score	0.017499 (rank : 143)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	154	Target Neighborhood Hits	1202	Shared Neighborhood Hits	33
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RAD50_MOUSE
NC score	0.017486 (rank : 144)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	154	Target Neighborhood Hits	1366	Shared Neighborhood Hits	27
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

CO4A2_HUMAN
NC score	0.017227 (rank : 145)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	154	Target Neighborhood Hits	454	Shared Neighborhood Hits	15
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CJ006_MOUSE
NC score	0.017120 (rank : 146)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P9P0, Q8C041, Q8C0J5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf6 homolog.

CHD9_MOUSE
NC score	0.017103 (rank : 147)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	154	Target Neighborhood Hits	427	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

HUWE1_MOUSE
NC score	0.016457 (rank : 148)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	154	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.016404 (rank : 149)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	154	Target Neighborhood Hits	443	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

SH2D3_HUMAN
NC score	0.015963 (rank : 150)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	154	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

WASIP_HUMAN
NC score	0.015555 (rank : 151)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	154	Target Neighborhood Hits	458	Shared Neighborhood Hits	18
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

FGD5_HUMAN
NC score	0.015310 (rank : 152)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	154	Target Neighborhood Hits	235	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

CO5A2_HUMAN
NC score	0.014890 (rank : 153)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	154	Target Neighborhood Hits	760	Shared Neighborhood Hits	20
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

BAZ2A_HUMAN
NC score	0.014502 (rank : 154)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	154	Target Neighborhood Hits	780	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CBP_MOUSE
NC score	0.014266 (rank : 155)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	154	Target Neighborhood Hits	1051	Shared Neighborhood Hits	27
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DJBP_MOUSE
NC score	0.013817 (rank : 156)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	154	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

CO1A1_HUMAN
NC score	0.013738 (rank : 157)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	154	Target Neighborhood Hits	475	Shared Neighborhood Hits	15
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

ERC2_HUMAN
NC score	0.013625 (rank : 158)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	154	Target Neighborhood Hits	1156	Shared Neighborhood Hits	25
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
NC score	0.013496 (rank : 159)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	154	Target Neighborhood Hits	1166	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

CENPE_HUMAN
NC score	0.013088 (rank : 160)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	154	Target Neighborhood Hits	2060	Shared Neighborhood Hits	37
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

TEX15_HUMAN
NC score	0.013073 (rank : 161)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	154	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

NAF1_MOUSE
NC score	0.012988 (rank : 162)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	154	Target Neighborhood Hits	852	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

ANK2_HUMAN
NC score	0.012902 (rank : 163)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	154	Target Neighborhood Hits	1615	Shared Neighborhood Hits	44
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CDKL5_HUMAN
NC score	0.012767 (rank : 164)	θ value	0.00509761 (rank : 10)
Query Neighborhood Hits	154	Target Neighborhood Hits	967	Shared Neighborhood Hits	14
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

NCOA2_MOUSE
NC score	0.012552 (rank : 165)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	154	Target Neighborhood Hits	281	Shared Neighborhood Hits	18
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

EGR1_MOUSE
NC score	0.011908 (rank : 166)	θ value	0.0431538 (rank : 15)
Query Neighborhood Hits	154	Target Neighborhood Hits	816	Shared Neighborhood Hits	15
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

NAF1_HUMAN
NC score	0.011862 (rank : 167)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	154	Target Neighborhood Hits	937	Shared Neighborhood Hits	17
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

MCCA_HUMAN
NC score	0.011464 (rank : 168)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	154	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RQ3, Q59ES4, Q9H959, Q9NS97	Gene names	MCCC1, MCCA
Domain Architecture
Description	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial precursor (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (MCCase subunit alpha) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) (3- methylcrotonyl-CoA carboxylase biotin-containing subunit).

BSN_HUMAN
NC score	0.011301 (rank : 169)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	154	Target Neighborhood Hits	1537	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DMXL1_MOUSE
NC score	0.010927 (rank : 170)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	154	Target Neighborhood Hits	257	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

B3A3_MOUSE
NC score	0.010344 (rank : 171)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	154	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

RAPH1_HUMAN
NC score	0.009803 (rank : 172)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	154	Target Neighborhood Hits	593	Shared Neighborhood Hits	16
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

UBP4_HUMAN
NC score	0.008657 (rank : 173)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	154	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

EGR1_HUMAN
NC score	0.007959 (rank : 174)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	154	Target Neighborhood Hits	788	Shared Neighborhood Hits	8
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

NEDD4_MOUSE
NC score	0.007789 (rank : 175)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	154	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

K1C9_HUMAN
NC score	0.007049 (rank : 176)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	154	Target Neighborhood Hits	526	Shared Neighborhood Hits	15
SwissProt Accessions	P35527, O00109, Q14665	Gene names	KRT9
Domain Architecture
Description	Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9).

GP115_HUMAN
NC score	0.006190 (rank : 177)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	154	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

HCN4_MOUSE
NC score	0.005232 (rank : 178)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	154	Target Neighborhood Hits	284	Shared Neighborhood Hits	9
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

PRDM2_HUMAN
NC score	0.004908 (rank : 179)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	154	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

CAC1F_HUMAN
NC score	0.003901 (rank : 180)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

STK6_HUMAN
NC score	0.001678 (rank : 181)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	154	Target Neighborhood Hits	916	Shared Neighborhood Hits	7
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).

ZFP37_MOUSE
NC score	-0.000474 (rank : 182)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	154	Target Neighborhood Hits	906	Shared Neighborhood Hits	16
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).