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Network neighborhood for query Sequence : NF2L2_HUMAN

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NF2L2_HUMAN
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NF2L2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

NF2L2_MOUSE
θ value	0 (rank : 2)	NC score	0.958956 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	183	Shared Neighborhood Hits	46
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

NF2L1_HUMAN
θ value	1.36269e-64 (rank : 3)	NC score	0.874619 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	169	Shared Neighborhood Hits	35
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L1_MOUSE
θ value	2.25659e-51 (rank : 4)	NC score	0.858907 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	185	Shared Neighborhood Hits	34
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

NF2L3_HUMAN
θ value	2.11701e-41 (rank : 5)	NC score	0.839513 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	150	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NFE2_HUMAN
θ value	6.81017e-40 (rank : 6)	NC score	0.902181 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q16621, Q07720, Q6ICV9	Gene names	NFE2
Domain Architecture	No domain graphic available
Description	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2).

NF2L3_MOUSE
θ value	7.52953e-39 (rank : 7)	NC score	0.845045 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

BACH2_HUMAN
θ value	6.85773e-16 (rank : 8)	NC score	0.378538 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	234	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BACH2_MOUSE
θ value	8.95645e-16 (rank : 9)	NC score	0.381660 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BACH1_MOUSE
θ value	7.58209e-15 (rank : 10)	NC score	0.380064 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	289	Shared Neighborhood Hits	31
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

BACH1_HUMAN
θ value	9.90251e-15 (rank : 11)	NC score	0.381117 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	289	Shared Neighborhood Hits	32
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

JUND_HUMAN
θ value	0.00102713 (rank : 12)	NC score	0.332501 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	122	Shared Neighborhood Hits	35
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUND_MOUSE
θ value	0.00102713 (rank : 13)	NC score	0.335471 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	134	Shared Neighborhood Hits	37
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

JUN_HUMAN
θ value	0.00134147 (rank : 14)	NC score	0.327839 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

JUN_MOUSE
θ value	0.00134147 (rank : 15)	NC score	0.328212 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	145	Shared Neighborhood Hits	33
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

JUNB_HUMAN
θ value	0.00298849 (rank : 16)	NC score	0.329107 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	27
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

JUNB_MOUSE
θ value	0.00298849 (rank : 17)	NC score	0.324241 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	116	Shared Neighborhood Hits	28
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

SRRM2_HUMAN
θ value	0.00869519 (rank : 18)	NC score	0.048315 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DSPP_HUMAN
θ value	0.0148317 (rank : 19)	NC score	0.068435 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	645	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MAF_HUMAN
θ value	0.0330416 (rank : 20)	NC score	0.171022 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	O75444, Q9UP93	Gene names	MAF
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

SALL3_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.015863 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	1066	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

ANK2_HUMAN
θ value	0.0736092 (rank : 22)	NC score	0.024753 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	1615	Shared Neighborhood Hits	32
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

DSPP_MOUSE
θ value	0.0736092 (rank : 23)	NC score	0.067594 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	491	Shared Neighborhood Hits	15
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MAF_MOUSE
θ value	0.0736092 (rank : 24)	NC score	0.168054 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	95	Shared Neighborhood Hits	21
SwissProt Accessions	P54843	Gene names	Maf, Maf2
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

3MG_MOUSE
θ value	0.0961366 (rank : 25)	NC score	0.059261 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q04841, Q64182	Gene names	Mpg, Mid1
Domain Architecture
Description	DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-methyladenine DNA glycosidase) (ADPG) (3-alkyladenine DNA glycosylase) (N-methylpurine- DNA glycosylase).

GR65_HUMAN
θ value	0.163984 (rank : 26)	NC score	0.038794 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

ATF6A_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.094944 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

PHLPP_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.019674 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	394	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

BATF_MOUSE
θ value	0.47712 (rank : 29)	NC score	0.175558 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

EPAS1_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.022972 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

CSPG3_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.010796 (rank : 116)
Query Neighborhood Hits	109	Target Neighborhood Hits	676	Shared Neighborhood Hits	10
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

NCOA6_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.025267 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	1202	Shared Neighborhood Hits	24
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RABE1_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.032885 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	1104	Shared Neighborhood Hits	38
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	0.813845 (rank : 34)	NC score	0.034618 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	1105	Shared Neighborhood Hits	34
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

SPB4_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.008840 (rank : 123)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	P48594	Gene names	SERPINB4, SCCA2
Domain Architecture
Description	Serpin B4 (Squamous cell carcinoma antigen 2) (SCCA-2) (Leupin).

TACC1_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.024177 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	597	Shared Neighborhood Hits	20
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

ZN516_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.005763 (rank : 128)
Query Neighborhood Hits	109	Target Neighborhood Hits	1197	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

FOS_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.120061 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	P01100, P18849	Gene names	FOS, G0S7
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7).

FOS_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.121434 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

MAFB_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.174394 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

MAFB_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.174824 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	24
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

N4BP2_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.041537 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

SYCP1_MOUSE
θ value	1.06291 (rank : 43)	NC score	0.018908 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	1456	Shared Neighborhood Hits	30
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CBP_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.019635 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	941	Shared Neighborhood Hits	17
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CDKL5_HUMAN
θ value	1.81305 (rank : 45)	NC score	0.004518 (rank : 130)
Query Neighborhood Hits	109	Target Neighborhood Hits	967	Shared Neighborhood Hits	14
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

KCC2B_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.002384 (rank : 133)
Query Neighborhood Hits	109	Target Neighborhood Hits	866	Shared Neighborhood Hits	9
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

PHLPP_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.017048 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	604	Shared Neighborhood Hits	11
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SAPS3_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.018379 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

DHX29_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.016882 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

GOGB1_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.019593 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	2297	Shared Neighborhood Hits	49
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MRCKB_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.008286 (rank : 125)
Query Neighborhood Hits	109	Target Neighborhood Hits	2239	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MUC1_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.031498 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	388	Shared Neighborhood Hits	13
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MY18A_MOUSE
θ value	2.36792 (rank : 53)	NC score	0.019935 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	1989	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PKN2_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.003924 (rank : 132)
Query Neighborhood Hits	109	Target Neighborhood Hits	892	Shared Neighborhood Hits	10
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

AKAP8_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.026898 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

CK5P2_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.022004 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	1433	Shared Neighborhood Hits	34
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CKAP4_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.025967 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	596	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MY18A_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.014969 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	1929	Shared Neighborhood Hits	41
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NCOR1_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.033153 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	521	Shared Neighborhood Hits	23
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PKN2_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.004430 (rank : 131)
Query Neighborhood Hits	109	Target Neighborhood Hits	899	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

SUFU_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.031944 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UMX1, Q7LCP7, Q9NT90, Q9NZ07, Q9UHK2, Q9UHM8, Q9UMY0	Gene names	SUFU
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog (SUFUH).

SUFU_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.032067 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P7, Q8C8B4, Q99JG0, Q9D521, Q9JLU1	Gene names	Sufu
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog.

3BP5_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.019325 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	375	Shared Neighborhood Hits	15
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

ATF4_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.022758 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

CCD45_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.018324 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	663	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CLMN_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.008472 (rank : 124)
Query Neighborhood Hits	109	Target Neighborhood Hits	180	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CREB3_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.158798 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	25
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

DCR1C_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.016415 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4J0, Q8BG72, Q8BTT1	Gene names	Dclre1c, Art, Snm1l
Domain Architecture	No domain graphic available
Description	Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C protein) (mArt protein) (SNM1-like protein).

DYHC_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.019892 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	733	Shared Neighborhood Hits	21
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.018632 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	729	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

NACAM_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.024756 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	1866	Shared Neighborhood Hits	32
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

UBN1_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.026497 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

BCL9_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.019767 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	1008	Shared Neighborhood Hits	22
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CASL_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.009830 (rank : 121)
Query Neighborhood Hits	109	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CCD41_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.015729 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	1399	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

DHX29_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.012886 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

GLU2B_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.018025 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	377	Shared Neighborhood Hits	15
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

IWS1_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.028584 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	1241	Shared Neighborhood Hits	27
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

M3K3_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.002028 (rank : 135)
Query Neighborhood Hits	109	Target Neighborhood Hits	885	Shared Neighborhood Hits	9
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

RPB1_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.021115 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	362	Shared Neighborhood Hits	12
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.021088 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	363	Shared Neighborhood Hits	12
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SMAD4_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.009576 (rank : 122)
Query Neighborhood Hits	109	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

SPA9_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.005372 (rank : 129)
Query Neighborhood Hits	109	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WD7, Q6UWP9, Q86WD6, Q86YP6, Q86YP7	Gene names	SERPINA9, GCET1, SERPINA11
Domain Architecture	No domain graphic available
Description	Serpin A9 precursor (Germinal center B-cell expressed transcript 1 protein).

ZBED4_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.019140 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O75132, Q9UGG8	Gene names	ZBED4, KIAA0637
Domain Architecture
Description	Zinc finger BED domain-containing protein 4.

AT2B2_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.007015 (rank : 126)
Query Neighborhood Hits	109	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q01814, O00766, Q12994, Q16818	Gene names	ATP2B2, PMCA2
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 2 (EC 3.6.3.8) (PMCA2) (Plasma membrane calcium pump isoform 2) (Plasma membrane calcium ATPase isoform 2).

AT2B2_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.006732 (rank : 127)
Query Neighborhood Hits	109	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0K7, O88863	Gene names	Atp2b2, Pmca2
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 2 (EC 3.6.3.8) (PMCA2) (Plasma membrane calcium pump isoform 2) (Plasma membrane calcium ATPase isoform 2).

BANK1_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.014921 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

CE290_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.013246 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	1553	Shared Neighborhood Hits	31
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CKAP4_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.020020 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

HGS_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.014576 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HUWE1_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.009863 (rank : 120)
Query Neighborhood Hits	109	Target Neighborhood Hits	406	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

MAGC1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.015355 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MYH3_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.012247 (rank : 115)
Query Neighborhood Hits	109	Target Neighborhood Hits	1660	Shared Neighborhood Hits	29
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PTN3_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.002174 (rank : 134)
Query Neighborhood Hits	109	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

SDC2_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.015283 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P43407	Gene names	Sdc2, Hspg1, Synd2
Domain Architecture
Description	Syndecan-2 precursor (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG).

SFRIP_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.020324 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	530	Shared Neighborhood Hits	18
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

AKAP8_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.017126 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	166	Shared Neighborhood Hits	7
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

ANR26_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.014977 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	1614	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BSN_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.021099 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	1537	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CIC_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.010178 (rank : 119)
Query Neighborhood Hits	109	Target Neighborhood Hits	992	Shared Neighborhood Hits	19
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

EI2BE_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.010270 (rank : 118)
Query Neighborhood Hits	109	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

ERC2_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.012642 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	1156	Shared Neighborhood Hits	21
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.012743 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	1166	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

FOSL1_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.123780 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	112	Shared Neighborhood Hits	25
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOSL1_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.123081 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	25
SwissProt Accessions	P48755, O35285	Gene names	Fosl1, Fra1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

HGS_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.013546 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	517	Shared Neighborhood Hits	17
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

K1024_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.010757 (rank : 117)
Query Neighborhood Hits	109	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3V7, Q69ZS9	Gene names	Kiaa1024
Domain Architecture
Description	UPF0258 protein KIAA1024 (Protein DD1).

M3K3_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.001607 (rank : 136)
Query Neighborhood Hits	109	Target Neighborhood Hits	876	Shared Neighborhood Hits	9
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

SIN1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.016622 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BPZ7, Q00426	Gene names	MAPKAP1, SIN1
Domain Architecture
Description	Stress-activated map kinase-interacting protein 1 (SAPK-interacting protein 1) (Putative Ras inhibitor JC310).

ATF1_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.054790 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

ATF1_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.051839 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

ATF2_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.058128 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	402	Shared Neighborhood Hits	27
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.058225 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	397	Shared Neighborhood Hits	28
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

ATF3_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.144150 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	120	Shared Neighborhood Hits	33
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

ATF3_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.148653 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

ATF7_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.062287 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	333	Shared Neighborhood Hits	25
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.058053 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	286	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

BATF_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.149154 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

CREB3_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.068353 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	138	Shared Neighborhood Hits	20
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

CREB5_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.091378 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	222	Shared Neighborhood Hits	25
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

CREM_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.063083 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	63	Shared Neighborhood Hits	17
SwissProt Accessions	Q03060, Q16114, Q16116, Q9NZB9	Gene names	CREM
Domain Architecture
Description	cAMP-responsive element modulator.

CREM_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.063788 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

FOSB_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.112893 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

FOSB_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.110809 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

FOSL2_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.114518 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	158	Shared Neighborhood Hits	27
SwissProt Accessions	P15408	Gene names	FOSL2, FRA2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

FOSL2_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.109921 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	P47930	Gene names	Fosl2, Fra-2, Fra2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

MAFF_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.081906 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

MAFF_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.082726 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

MAFG_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.135730 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	O15525	Gene names	MAFG
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF).

MAFG_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.135622 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	O54790	Gene names	Mafg
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G).

MAFK_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.148805 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	O60675	Gene names	MAFK
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

MAFK_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.145717 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	Q61827, Q60600	Gene names	Mafk, Nfe2u
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

NRL_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.081348 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	P54845	Gene names	NRL
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL) (D14S46E).

NRL_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.092909 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	P54846	Gene names	Nrl
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL).

XBP1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.183683 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

XBP1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.160090 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	99	Shared Neighborhood Hits	22
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

Hits sorted by NC score

NF2L2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

NF2L2_MOUSE
NC score	0.958956 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	183	Shared Neighborhood Hits	46
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

NFE2_HUMAN
NC score	0.902181 (rank : 3)	θ value	6.81017e-40 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q16621, Q07720, Q6ICV9	Gene names	NFE2
Domain Architecture	No domain graphic available
Description	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2).

NF2L1_HUMAN
NC score	0.874619 (rank : 4)	θ value	1.36269e-64 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	169	Shared Neighborhood Hits	35
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L1_MOUSE
NC score	0.858907 (rank : 5)	θ value	2.25659e-51 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	185	Shared Neighborhood Hits	34
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

NF2L3_MOUSE
NC score	0.845045 (rank : 6)	θ value	7.52953e-39 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NF2L3_HUMAN
NC score	0.839513 (rank : 7)	θ value	2.11701e-41 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	150	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

BACH2_MOUSE
NC score	0.381660 (rank : 8)	θ value	8.95645e-16 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BACH1_HUMAN
NC score	0.381117 (rank : 9)	θ value	9.90251e-15 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	289	Shared Neighborhood Hits	32
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

BACH1_MOUSE
NC score	0.380064 (rank : 10)	θ value	7.58209e-15 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	289	Shared Neighborhood Hits	31
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

BACH2_HUMAN
NC score	0.378538 (rank : 11)	θ value	6.85773e-16 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	234	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

JUND_MOUSE
NC score	0.335471 (rank : 12)	θ value	0.00102713 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	134	Shared Neighborhood Hits	37
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

JUND_HUMAN
NC score	0.332501 (rank : 13)	θ value	0.00102713 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	122	Shared Neighborhood Hits	35
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUNB_HUMAN
NC score	0.329107 (rank : 14)	θ value	0.00298849 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	27
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

JUN_MOUSE
NC score	0.328212 (rank : 15)	θ value	0.00134147 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	145	Shared Neighborhood Hits	33
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

JUN_HUMAN
NC score	0.327839 (rank : 16)	θ value	0.00134147 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

JUNB_MOUSE
NC score	0.324241 (rank : 17)	θ value	0.00298849 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	116	Shared Neighborhood Hits	28
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

XBP1_HUMAN
NC score	0.183683 (rank : 18)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

BATF_MOUSE
NC score	0.175558 (rank : 19)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

MAFB_MOUSE
NC score	0.174824 (rank : 20)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	24
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

MAFB_HUMAN
NC score	0.174394 (rank : 21)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

MAF_HUMAN
NC score	0.171022 (rank : 22)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	O75444, Q9UP93	Gene names	MAF
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

MAF_MOUSE
NC score	0.168054 (rank : 23)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	95	Shared Neighborhood Hits	21
SwissProt Accessions	P54843	Gene names	Maf, Maf2
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

XBP1_MOUSE
NC score	0.160090 (rank : 24)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	109	Target Neighborhood Hits	99	Shared Neighborhood Hits	22
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

CREB3_MOUSE
NC score	0.158798 (rank : 25)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	25
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

BATF_HUMAN
NC score	0.149154 (rank : 26)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

MAFK_HUMAN
NC score	0.148805 (rank : 27)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	109	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	O60675	Gene names	MAFK
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

ATF3_MOUSE
NC score	0.148653 (rank : 28)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	109	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

MAFK_MOUSE
NC score	0.145717 (rank : 29)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	109	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	Q61827, Q60600	Gene names	Mafk, Nfe2u
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

ATF3_HUMAN
NC score	0.144150 (rank : 30)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	120	Shared Neighborhood Hits	33
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

MAFG_HUMAN
NC score	0.135730 (rank : 31)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	O15525	Gene names	MAFG
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF).

MAFG_MOUSE
NC score	0.135622 (rank : 32)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	O54790	Gene names	Mafg
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G).

FOSL1_HUMAN
NC score	0.123780 (rank : 33)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	112	Shared Neighborhood Hits	25
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOSL1_MOUSE
NC score	0.123081 (rank : 34)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	25
SwissProt Accessions	P48755, O35285	Gene names	Fosl1, Fra1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOS_MOUSE
NC score	0.121434 (rank : 35)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

FOS_HUMAN
NC score	0.120061 (rank : 36)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	72	Shared Neighborhood Hits	21
SwissProt Accessions	P01100, P18849	Gene names	FOS, G0S7
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7).

FOSL2_HUMAN
NC score	0.114518 (rank : 37)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	109	Target Neighborhood Hits	158	Shared Neighborhood Hits	27
SwissProt Accessions	P15408	Gene names	FOSL2, FRA2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

FOSB_HUMAN
NC score	0.112893 (rank : 38)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	109	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

FOSB_MOUSE
NC score	0.110809 (rank : 39)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	109	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

FOSL2_MOUSE
NC score	0.109921 (rank : 40)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	109	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	P47930	Gene names	Fosl2, Fra-2, Fra2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

ATF6A_HUMAN
NC score	0.094944 (rank : 41)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

NRL_MOUSE
NC score	0.092909 (rank : 42)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	109	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	P54846	Gene names	Nrl
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL).

CREB5_HUMAN
NC score	0.091378 (rank : 43)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	109	Target Neighborhood Hits	222	Shared Neighborhood Hits	25
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

MAFF_MOUSE
NC score	0.082726 (rank : 44)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	109	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

MAFF_HUMAN
NC score	0.081906 (rank : 45)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	109	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

NRL_HUMAN
NC score	0.081348 (rank : 46)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	109	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	P54845	Gene names	NRL
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL) (D14S46E).

DSPP_HUMAN
NC score	0.068435 (rank : 47)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	645	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CREB3_HUMAN
NC score	0.068353 (rank : 48)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	109	Target Neighborhood Hits	138	Shared Neighborhood Hits	20
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

DSPP_MOUSE
NC score	0.067594 (rank : 49)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	491	Shared Neighborhood Hits	15
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CREM_MOUSE
NC score	0.063788 (rank : 50)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	109	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

CREM_HUMAN
NC score	0.063083 (rank : 51)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	109	Target Neighborhood Hits	63	Shared Neighborhood Hits	17
SwissProt Accessions	Q03060, Q16114, Q16116, Q9NZB9	Gene names	CREM
Domain Architecture
Description	cAMP-responsive element modulator.

ATF7_HUMAN
NC score	0.062287 (rank : 52)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	109	Target Neighborhood Hits	333	Shared Neighborhood Hits	25
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

3MG_MOUSE
NC score	0.059261 (rank : 53)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q04841, Q64182	Gene names	Mpg, Mid1
Domain Architecture
Description	DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-methyladenine DNA glycosidase) (ADPG) (3-alkyladenine DNA glycosylase) (N-methylpurine- DNA glycosylase).

ATF2_MOUSE
NC score	0.058225 (rank : 54)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	397	Shared Neighborhood Hits	28
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

ATF2_HUMAN
NC score	0.058128 (rank : 55)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	402	Shared Neighborhood Hits	27
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF7_MOUSE
NC score	0.058053 (rank : 56)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	109	Target Neighborhood Hits	286	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF1_HUMAN
NC score	0.054790 (rank : 57)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

ATF1_MOUSE
NC score	0.051839 (rank : 58)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

SRRM2_HUMAN
NC score	0.048315 (rank : 59)	θ value	0.00869519 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

N4BP2_HUMAN
NC score	0.041537 (rank : 60)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

GR65_HUMAN
NC score	0.038794 (rank : 61)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

RABE1_MOUSE
NC score	0.034618 (rank : 62)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	1105	Shared Neighborhood Hits	34
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

NCOR1_MOUSE
NC score	0.033153 (rank : 63)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	521	Shared Neighborhood Hits	23
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

RABE1_HUMAN
NC score	0.032885 (rank : 64)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	1104	Shared Neighborhood Hits	38
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

SUFU_MOUSE
NC score	0.032067 (rank : 65)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P7, Q8C8B4, Q99JG0, Q9D521, Q9JLU1	Gene names	Sufu
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog.

SUFU_HUMAN
NC score	0.031944 (rank : 66)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UMX1, Q7LCP7, Q9NT90, Q9NZ07, Q9UHK2, Q9UHM8, Q9UMY0	Gene names	SUFU
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog (SUFUH).

MUC1_MOUSE
NC score	0.031498 (rank : 67)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	388	Shared Neighborhood Hits	13
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

IWS1_HUMAN
NC score	0.028584 (rank : 68)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	1241	Shared Neighborhood Hits	27
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AKAP8_MOUSE
NC score	0.026898 (rank : 69)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

UBN1_HUMAN
NC score	0.026497 (rank : 70)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

CKAP4_MOUSE
NC score	0.025967 (rank : 71)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	596	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

NCOA6_HUMAN
NC score	0.025267 (rank : 72)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	1202	Shared Neighborhood Hits	24
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NACAM_MOUSE
NC score	0.024756 (rank : 73)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	1866	Shared Neighborhood Hits	32
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ANK2_HUMAN
NC score	0.024753 (rank : 74)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	1615	Shared Neighborhood Hits	32
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TACC1_HUMAN
NC score	0.024177 (rank : 75)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	597	Shared Neighborhood Hits	20
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

EPAS1_MOUSE
NC score	0.022972 (rank : 76)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

ATF4_MOUSE
NC score	0.022758 (rank : 77)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q06507, Q61906	Gene names	Atf4
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-4 (C/EBP-related ATF) (C/ATF) (TAXREB67 homolog).

CK5P2_HUMAN
NC score	0.022004 (rank : 78)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	1433	Shared Neighborhood Hits	34
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

RPB1_HUMAN
NC score	0.021115 (rank : 79)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	362	Shared Neighborhood Hits	12
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

BSN_HUMAN
NC score	0.021099 (rank : 80)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	1537	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RPB1_MOUSE
NC score	0.021088 (rank : 81)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	363	Shared Neighborhood Hits	12
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SFRIP_HUMAN
NC score	0.020324 (rank : 82)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	530	Shared Neighborhood Hits	18
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CKAP4_HUMAN
NC score	0.020020 (rank : 83)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MY18A_MOUSE
NC score	0.019935 (rank : 84)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	1989	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

DYHC_HUMAN
NC score	0.019892 (rank : 85)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	733	Shared Neighborhood Hits	21
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

BCL9_HUMAN
NC score	0.019767 (rank : 86)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	1008	Shared Neighborhood Hits	22
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

PHLPP_MOUSE
NC score	0.019674 (rank : 87)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	394	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

CBP_HUMAN
NC score	0.019635 (rank : 88)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	941	Shared Neighborhood Hits	17
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GOGB1_HUMAN
NC score	0.019593 (rank : 89)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	2297	Shared Neighborhood Hits	49
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

3BP5_HUMAN
NC score	0.019325 (rank : 90)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	375	Shared Neighborhood Hits	15
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

ZBED4_HUMAN
NC score	0.019140 (rank : 91)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O75132, Q9UGG8	Gene names	ZBED4, KIAA0637
Domain Architecture
Description	Zinc finger BED domain-containing protein 4.

SYCP1_MOUSE
NC score	0.018908 (rank : 92)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	1456	Shared Neighborhood Hits	30
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

DYHC_MOUSE
NC score	0.018632 (rank : 93)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	729	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

SAPS3_MOUSE
NC score	0.018379 (rank : 94)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

CCD45_MOUSE
NC score	0.018324 (rank : 95)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	663	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

GLU2B_HUMAN
NC score	0.018025 (rank : 96)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	377	Shared Neighborhood Hits	15
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

AKAP8_HUMAN
NC score	0.017126 (rank : 97)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	166	Shared Neighborhood Hits	7
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

PHLPP_HUMAN
NC score	0.017048 (rank : 98)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	604	Shared Neighborhood Hits	11
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

DHX29_HUMAN
NC score	0.016882 (rank : 99)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

SIN1_HUMAN
NC score	0.016622 (rank : 100)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BPZ7, Q00426	Gene names	MAPKAP1, SIN1
Domain Architecture
Description	Stress-activated map kinase-interacting protein 1 (SAPK-interacting protein 1) (Putative Ras inhibitor JC310).

DCR1C_MOUSE
NC score	0.016415 (rank : 101)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4J0, Q8BG72, Q8BTT1	Gene names	Dclre1c, Art, Snm1l
Domain Architecture	No domain graphic available
Description	Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C protein) (mArt protein) (SNM1-like protein).

SALL3_HUMAN
NC score	0.015863 (rank : 102)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	1066	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

CCD41_MOUSE
NC score	0.015729 (rank : 103)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	1399	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MAGC1_HUMAN
NC score	0.015355 (rank : 104)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SDC2_MOUSE
NC score	0.015283 (rank : 105)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P43407	Gene names	Sdc2, Hspg1, Synd2
Domain Architecture
Description	Syndecan-2 precursor (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG).

ANR26_HUMAN
NC score	0.014977 (rank : 106)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	1614	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MY18A_HUMAN
NC score	0.014969 (rank : 107)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	1929	Shared Neighborhood Hits	41
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

BANK1_MOUSE
NC score	0.014921 (rank : 108)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

HGS_MOUSE
NC score	0.014576 (rank : 109)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
NC score	0.013546 (rank : 110)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	517	Shared Neighborhood Hits	17
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

CE290_HUMAN
NC score	0.013246 (rank : 111)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	1553	Shared Neighborhood Hits	31
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

DHX29_MOUSE
NC score	0.012886 (rank : 112)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

ERC2_MOUSE
NC score	0.012743 (rank : 113)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	1166	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ERC2_HUMAN
NC score	0.012642 (rank : 114)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	1156	Shared Neighborhood Hits	21
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

MYH3_HUMAN
NC score	0.012247 (rank : 115)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	1660	Shared Neighborhood Hits	29
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

CSPG3_HUMAN
NC score	0.010796 (rank : 116)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	676	Shared Neighborhood Hits	10
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

K1024_MOUSE
NC score	0.010757 (rank : 117)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3V7, Q69ZS9	Gene names	Kiaa1024
Domain Architecture
Description	UPF0258 protein KIAA1024 (Protein DD1).

EI2BE_HUMAN
NC score	0.010270 (rank : 118)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

CIC_HUMAN
NC score	0.010178 (rank : 119)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	992	Shared Neighborhood Hits	19
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HUWE1_MOUSE
NC score	0.009863 (rank : 120)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	406	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

CASL_HUMAN
NC score	0.009830 (rank : 121)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

SMAD4_HUMAN
NC score	0.009576 (rank : 122)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

SPB4_HUMAN
NC score	0.008840 (rank : 123)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	P48594	Gene names	SERPINB4, SCCA2
Domain Architecture
Description	Serpin B4 (Squamous cell carcinoma antigen 2) (SCCA-2) (Leupin).

CLMN_MOUSE
NC score	0.008472 (rank : 124)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	180	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

MRCKB_HUMAN
NC score	0.008286 (rank : 125)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	2239	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

AT2B2_HUMAN
NC score	0.007015 (rank : 126)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q01814, O00766, Q12994, Q16818	Gene names	ATP2B2, PMCA2
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 2 (EC 3.6.3.8) (PMCA2) (Plasma membrane calcium pump isoform 2) (Plasma membrane calcium ATPase isoform 2).

AT2B2_MOUSE
NC score	0.006732 (rank : 127)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0K7, O88863	Gene names	Atp2b2, Pmca2
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 2 (EC 3.6.3.8) (PMCA2) (Plasma membrane calcium pump isoform 2) (Plasma membrane calcium ATPase isoform 2).

ZN516_MOUSE
NC score	0.005763 (rank : 128)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	1197	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

SPA9_HUMAN
NC score	0.005372 (rank : 129)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WD7, Q6UWP9, Q86WD6, Q86YP6, Q86YP7	Gene names	SERPINA9, GCET1, SERPINA11
Domain Architecture	No domain graphic available
Description	Serpin A9 precursor (Germinal center B-cell expressed transcript 1 protein).

CDKL5_HUMAN
NC score	0.004518 (rank : 130)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	967	Shared Neighborhood Hits	14
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

PKN2_MOUSE
NC score	0.004430 (rank : 131)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	899	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

PKN2_HUMAN
NC score	0.003924 (rank : 132)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	892	Shared Neighborhood Hits	10
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

KCC2B_HUMAN
NC score	0.002384 (rank : 133)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	866	Shared Neighborhood Hits	9
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

PTN3_HUMAN
NC score	0.002174 (rank : 134)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

M3K3_HUMAN
NC score	0.002028 (rank : 135)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	885	Shared Neighborhood Hits	9
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

M3K3_MOUSE
NC score	0.001607 (rank : 136)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	876	Shared Neighborhood Hits	9
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).