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Network neighborhood for query Sequence : DHX29_HUMAN

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DHX29_HUMAN
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DHX29_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DHX29_MOUSE
θ value	0 (rank : 2)	NC score	0.991082 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	103	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

DHX36_MOUSE
θ value	1.6163e-166 (rank : 3)	NC score	0.959894 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	114	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX57_HUMAN
θ value	3.4876e-161 (rank : 4)	NC score	0.954361 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_MOUSE
θ value	4.55495e-161 (rank : 5)	NC score	0.954149 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	125	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX36_HUMAN
θ value	2.95243e-160 (rank : 6)	NC score	0.964225 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX9_HUMAN
θ value	1.87085e-122 (rank : 7)	NC score	0.950076 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	29
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

DHX9_MOUSE
θ value	6.88586e-117 (rank : 8)	NC score	0.949457 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	72	Shared Neighborhood Hits	28
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

PRP16_HUMAN
θ value	2.92676e-75 (rank : 9)	NC score	0.891835 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

DHX33_MOUSE
θ value	1.90147e-66 (rank : 10)	NC score	0.890379 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX15_HUMAN
θ value	1.50663e-63 (rank : 11)	NC score	0.900041 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

DHX15_MOUSE
θ value	1.50663e-63 (rank : 12)	NC score	0.899898 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

DHX30_HUMAN
θ value	1.96772e-63 (rank : 13)	NC score	0.918843 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_MOUSE
θ value	1.66577e-62 (rank : 14)	NC score	0.917887 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX33_HUMAN
θ value	4.53632e-60 (rank : 15)	NC score	0.885999 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	40	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX34_MOUSE
θ value	4.85792e-54 (rank : 16)	NC score	0.900046 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	235	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX40_MOUSE
θ value	3.60269e-49 (rank : 17)	NC score	0.879670 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

DHX40_HUMAN
θ value	4.70527e-49 (rank : 18)	NC score	0.880117 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	34	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

DHX34_HUMAN
θ value	3.85808e-43 (rank : 19)	NC score	0.910141 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX35_HUMAN
θ value	3.85808e-43 (rank : 20)	NC score	0.892782 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

DHX8_HUMAN
θ value	1.12253e-42 (rank : 21)	NC score	0.880265 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

DHX16_HUMAN
θ value	2.76489e-41 (rank : 22)	NC score	0.850315 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	356	Shared Neighborhood Hits	61
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

YTDC2_HUMAN
θ value	4.568e-36 (rank : 23)	NC score	0.838151 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

DHX37_HUMAN
θ value	1.79631e-32 (rank : 24)	NC score	0.877816 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

DDX10_MOUSE
θ value	0.0252991 (rank : 25)	NC score	0.045246 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	233	Shared Neighborhood Hits	39
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX49_HUMAN
θ value	0.0330416 (rank : 26)	NC score	0.053491 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	223	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	0.0330416 (rank : 27)	NC score	0.050220 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

P52K_HUMAN
θ value	0.0330416 (rank : 28)	NC score	0.039591 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

DDX10_HUMAN
θ value	0.0431538 (rank : 29)	NC score	0.040537 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	210	Shared Neighborhood Hits	35
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

ROCK1_HUMAN
θ value	0.0431538 (rank : 30)	NC score	0.011370 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	2000	Shared Neighborhood Hits	54
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

MPP8_HUMAN
θ value	0.0736092 (rank : 31)	NC score	0.023525 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	948	Shared Neighborhood Hits	50
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CCD11_HUMAN
θ value	0.0961366 (rank : 32)	NC score	0.040272 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	822	Shared Neighborhood Hits	50
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

IFT81_HUMAN
θ value	0.0961366 (rank : 33)	NC score	0.037997 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	893	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

DDX21_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.059282 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	308	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

CI093_HUMAN
θ value	0.163984 (rank : 35)	NC score	0.036094 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	1088	Shared Neighborhood Hits	54
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

DDX50_HUMAN
θ value	0.163984 (rank : 36)	NC score	0.065888 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

ROCK1_MOUSE
θ value	0.163984 (rank : 37)	NC score	0.011929 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	2126	Shared Neighborhood Hits	61
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SYCP1_MOUSE
θ value	0.163984 (rank : 38)	NC score	0.030949 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	1456	Shared Neighborhood Hits	60
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

DDX50_MOUSE
θ value	0.21417 (rank : 39)	NC score	0.063227 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

PLEC1_HUMAN
θ value	0.21417 (rank : 40)	NC score	0.027990 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	1326	Shared Neighborhood Hits	63
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

CENPE_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.023641 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	2060	Shared Neighborhood Hits	73
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

LAMA2_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.017395 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	1092	Shared Neighborhood Hits	43
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SYS_HUMAN
θ value	0.365318 (rank : 43)	NC score	0.030914 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P49591, Q9NSE3	Gene names	SARS, SERS
Domain Architecture
Description	Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS).

DESP_HUMAN
θ value	0.47712 (rank : 44)	NC score	0.029671 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	1470	Shared Neighborhood Hits	60
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DIRA3_HUMAN
θ value	0.47712 (rank : 45)	NC score	0.005630 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	241	Shared Neighborhood Hits	2
SwissProt Accessions	O95661	Gene names	DIRAS3, ARHI, NOEY2, RHOI
Domain Architecture
Description	GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI).

LIPA1_HUMAN
θ value	0.47712 (rank : 46)	NC score	0.025065 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	1294	Shared Neighborhood Hits	55
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MYH10_MOUSE
θ value	0.47712 (rank : 47)	NC score	0.022099 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	1612	Shared Neighborhood Hits	68
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NBN_HUMAN
θ value	0.47712 (rank : 48)	NC score	0.024592 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	226	Shared Neighborhood Hits	14
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

ADA30_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.009591 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	391	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

LYAR_HUMAN
θ value	0.62314 (rank : 50)	NC score	0.040291 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NX58, Q6FI78, Q9NYS1	Gene names	LYAR
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

MYH10_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.021524 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	1620	Shared Neighborhood Hits	67
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SMC4_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.027812 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	830	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

TR150_MOUSE
θ value	0.62314 (rank : 53)	NC score	0.030848 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	468	Shared Neighborhood Hits	16
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

BPAEA_MOUSE
θ value	0.813845 (rank : 54)	NC score	0.032649 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	1480	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GOGB1_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.028246 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	2297	Shared Neighborhood Hits	73
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LAMA2_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.017289 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	1198	Shared Neighborhood Hits	40
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NOP14_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.036155 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	573	Shared Neighborhood Hits	45
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PHF20_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.025557 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	394	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

SYS_MOUSE
θ value	0.813845 (rank : 59)	NC score	0.029118 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P26638	Gene names	Sars, Sars1, Sers
Domain Architecture
Description	Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS).

XRCC4_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.036093 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	19
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

DDX21_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.051462 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	350	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

IFT81_MOUSE
θ value	1.06291 (rank : 62)	NC score	0.029468 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	959	Shared Neighborhood Hits	46
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

NTBP1_MOUSE
θ value	1.06291 (rank : 63)	NC score	0.025514 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	528	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

OGFR_MOUSE
θ value	1.06291 (rank : 64)	NC score	0.009474 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	584	Shared Neighborhood Hits	9
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

TP53B_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.018140 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	413	Shared Neighborhood Hits	13
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TXLNA_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.027796 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	846	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

DDX28_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.041466 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

MYH13_HUMAN
θ value	1.38821 (rank : 68)	NC score	0.019928 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	1504	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

PRPF3_HUMAN
θ value	1.38821 (rank : 69)	NC score	0.032257 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PRPF3_MOUSE
θ value	1.38821 (rank : 70)	NC score	0.032395 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

BICD1_MOUSE
θ value	1.81305 (rank : 71)	NC score	0.024390 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	837	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CENPK_MOUSE
θ value	1.81305 (rank : 72)	NC score	0.021124 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	149	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

CNTRB_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.026312 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

DYNA_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.024964 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	1194	Shared Neighborhood Hits	59
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

NEST_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.025088 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	1305	Shared Neighborhood Hits	51
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NIN_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.024507 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	1376	Shared Neighborhood Hits	56
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

SMC2_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.032990 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	1405	Shared Neighborhood Hits	67
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

ABC8A_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.005268 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

AL2SA_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.019048 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

CCD21_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.025379 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	1228	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

DDX31_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.039093 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

IQGA1_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.018497 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	250	Shared Neighborhood Hits	22
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

IQGA1_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.017427 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	219	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

NF2L2_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.016882 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

TXLNA_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.025715 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	982	Shared Neighborhood Hits	52
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

CE290_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.025772 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	1553	Shared Neighborhood Hits	64
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

DDX3Y_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.030416 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	126	Shared Neighborhood Hits	22
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

FBN3_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.001033 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	543	Shared Neighborhood Hits	5
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GOGA4_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.031561 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	1939	Shared Neighborhood Hits	68
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.021741 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	1168	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

ITAM_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.004184 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

NEK1_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.001689 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	1311	Shared Neighborhood Hits	34
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

NUMA1_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.026615 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	1523	Shared Neighborhood Hits	63
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

RAI1_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.007979 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TCRG1_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.025670 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	929	Shared Neighborhood Hits	46
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.025687 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	947	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

ZN318_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.015096 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	642	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

CCD27_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.025404 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	594	Shared Neighborhood Hits	39
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

FA47A_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.007171 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	451	Shared Neighborhood Hits	6
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

LATS1_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.000190 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	1027	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

LEO1_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.023271 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	946	Shared Neighborhood Hits	35
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NOC2L_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.017688 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WV70, Q8VE16	Gene names	Noc2l
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

PI3R5_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.013176 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SW28, Q3TU01, Q3UDZ2, Q8C215, Q8CGQ7	Gene names	Pik3r5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit).

CCD45_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.022668 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	525	Shared Neighborhood Hits	40
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

IF4A2_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.029990 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.029990 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

MYH3_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.020374 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	1660	Shared Neighborhood Hits	66
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYO9B_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.008068 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	311	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NOP14_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.026225 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	324	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PEPL_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.024137 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	1141	Shared Neighborhood Hits	56
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PL10_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.028899 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

PLCB1_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.016122 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	531	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

STMN4_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.017337 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	395	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.017334 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	395	Shared Neighborhood Hits	31
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

TPR_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.027580 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	1921	Shared Neighborhood Hits	73
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

A4_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.011307 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

A4_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.011536 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

ABCAA_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.003892 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABCCB_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.003416 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

DDX47_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.037772 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.038518 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX5_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.028055 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.028033 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

FTS1_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.008169 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q64362	Gene names	Fts, Fif, Ft1
Domain Architecture	No domain graphic available
Description	Fused toes protein (FT1).

GOGA4_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.028587 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	2034	Shared Neighborhood Hits	76
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RPTN_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.009656 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	650	Shared Neighborhood Hits	20
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

UTP6_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.012222 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYH9, Q8IX96, Q96BL2, Q9NQ91	Gene names	UTP6, C17orf40, HCA66, MHAT
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein) (Hepatocellular carcinoma-associated antigen 66).

AMFR2_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.003308 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

BFSP2_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.007697 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	423	Shared Neighborhood Hits	30
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

CP2CJ_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.000932 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P33261, P33259, Q8WZB1, Q8WZB2	Gene names	CYP2C19
Domain Architecture
Description	Cytochrome P450 2C19 (EC 1.14.13.80) ((R)-limonene 6-monooxygenase) (EC 1.14.13.48) ((S)-limonene 6-monooxygenase) (EC 1.14.13.49) ((S)- limonene 7-monooxygenase) (CYPIIC19) (P450-11A) (Mephenytoin 4- hydroxylase) (CYPIIC17) (P450-254C).

DDX3Y_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.026722 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	121	Shared Neighborhood Hits	21
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

F10A1_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.004165 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	312	Shared Neighborhood Hits	10
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

FOXN3_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.001161 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

GOGA1_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.020706 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	994	Shared Neighborhood Hits	51
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

ITA11_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.004034 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKX5, Q8WYI8, Q9UKQ1	Gene names	ITGA11
Domain Architecture
Description	Integrin alpha-11 precursor.

MA2A1_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.004080 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

NALP5_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.006651 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	560	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NF2L2_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.008711 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	183	Shared Neighborhood Hits	6
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

NUCB1_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.015962 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

PHF20_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.017129 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	513	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PI3R5_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.010885 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYR1, Q5G936, Q5G938, Q5G939, Q8IZ23, Q9Y2Y2	Gene names	PIK3R5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2).

RECQ1_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.017458 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RIMB1_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.016119 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	1479	Shared Neighborhood Hits	48
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TTC1_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.010351 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	417	Shared Neighborhood Hits	25
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

Hits sorted by NC score

DHX29_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DHX29_MOUSE
NC score	0.991082 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	103	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

DHX36_HUMAN
NC score	0.964225 (rank : 3)	θ value	2.95243e-160 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX36_MOUSE
NC score	0.959894 (rank : 4)	θ value	1.6163e-166 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	114	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX57_HUMAN
NC score	0.954361 (rank : 5)	θ value	3.4876e-161 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_MOUSE
NC score	0.954149 (rank : 6)	θ value	4.55495e-161 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	125	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX9_HUMAN
NC score	0.950076 (rank : 7)	θ value	1.87085e-122 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	29
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

DHX9_MOUSE
NC score	0.949457 (rank : 8)	θ value	6.88586e-117 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	72	Shared Neighborhood Hits	28
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

DHX30_HUMAN
NC score	0.918843 (rank : 9)	θ value	1.96772e-63 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_MOUSE
NC score	0.917887 (rank : 10)	θ value	1.66577e-62 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX34_HUMAN
NC score	0.910141 (rank : 11)	θ value	3.85808e-43 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX34_MOUSE
NC score	0.900046 (rank : 12)	θ value	4.85792e-54 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	235	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX15_HUMAN
NC score	0.900041 (rank : 13)	θ value	1.50663e-63 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

DHX15_MOUSE
NC score	0.899898 (rank : 14)	θ value	1.50663e-63 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

DHX35_HUMAN
NC score	0.892782 (rank : 15)	θ value	3.85808e-43 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

PRP16_HUMAN
NC score	0.891835 (rank : 16)	θ value	2.92676e-75 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

DHX33_MOUSE
NC score	0.890379 (rank : 17)	θ value	1.90147e-66 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX33_HUMAN
NC score	0.885999 (rank : 18)	θ value	4.53632e-60 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	40	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX8_HUMAN
NC score	0.880265 (rank : 19)	θ value	1.12253e-42 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

DHX40_HUMAN
NC score	0.880117 (rank : 20)	θ value	4.70527e-49 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	34	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

DHX40_MOUSE
NC score	0.879670 (rank : 21)	θ value	3.60269e-49 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

DHX37_HUMAN
NC score	0.877816 (rank : 22)	θ value	1.79631e-32 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

DHX16_HUMAN
NC score	0.850315 (rank : 23)	θ value	2.76489e-41 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	356	Shared Neighborhood Hits	61
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

YTDC2_HUMAN
NC score	0.838151 (rank : 24)	θ value	4.568e-36 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

DDX50_HUMAN
NC score	0.065888 (rank : 25)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.063227 (rank : 26)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX21_HUMAN
NC score	0.059282 (rank : 27)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	308	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX49_HUMAN
NC score	0.053491 (rank : 28)	θ value	0.0330416 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	223	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX21_MOUSE
NC score	0.051462 (rank : 29)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	350	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX49_MOUSE
NC score	0.050220 (rank : 30)	θ value	0.0330416 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX10_MOUSE
NC score	0.045246 (rank : 31)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	233	Shared Neighborhood Hits	39
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX28_HUMAN
NC score	0.041466 (rank : 32)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX10_HUMAN
NC score	0.040537 (rank : 33)	θ value	0.0431538 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	210	Shared Neighborhood Hits	35
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

LYAR_HUMAN
NC score	0.040291 (rank : 34)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NX58, Q6FI78, Q9NYS1	Gene names	LYAR
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

CCD11_HUMAN
NC score	0.040272 (rank : 35)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	822	Shared Neighborhood Hits	50
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

P52K_HUMAN
NC score	0.039591 (rank : 36)	θ value	0.0330416 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

DDX31_HUMAN
NC score	0.039093 (rank : 37)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX47_MOUSE
NC score	0.038518 (rank : 38)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

IFT81_HUMAN
NC score	0.037997 (rank : 39)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	893	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

DDX47_HUMAN
NC score	0.037772 (rank : 40)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

NOP14_HUMAN
NC score	0.036155 (rank : 41)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	573	Shared Neighborhood Hits	45
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

CI093_HUMAN
NC score	0.036094 (rank : 42)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	1088	Shared Neighborhood Hits	54
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

XRCC4_HUMAN
NC score	0.036093 (rank : 43)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	19
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

SMC2_HUMAN
NC score	0.032990 (rank : 44)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	1405	Shared Neighborhood Hits	67
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

BPAEA_MOUSE
NC score	0.032649 (rank : 45)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	1480	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PRPF3_MOUSE
NC score	0.032395 (rank : 46)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

PRPF3_HUMAN
NC score	0.032257 (rank : 47)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

GOGA4_MOUSE
NC score	0.031561 (rank : 48)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	1939	Shared Neighborhood Hits	68
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

SYCP1_MOUSE
NC score	0.030949 (rank : 49)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	1456	Shared Neighborhood Hits	60
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYS_HUMAN
NC score	0.030914 (rank : 50)	θ value	0.365318 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P49591, Q9NSE3	Gene names	SARS, SERS
Domain Architecture
Description	Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS).

TR150_MOUSE
NC score	0.030848 (rank : 51)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	468	Shared Neighborhood Hits	16
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

DDX3Y_MOUSE
NC score	0.030416 (rank : 52)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	126	Shared Neighborhood Hits	22
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

IF4A2_HUMAN
NC score	0.029990 (rank : 53)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.029990 (rank : 54)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DESP_HUMAN
NC score	0.029671 (rank : 55)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	1470	Shared Neighborhood Hits	60
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

IFT81_MOUSE
NC score	0.029468 (rank : 56)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	959	Shared Neighborhood Hits	46
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

SYS_MOUSE
NC score	0.029118 (rank : 57)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P26638	Gene names	Sars, Sars1, Sers
Domain Architecture
Description	Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS).

PL10_MOUSE
NC score	0.028899 (rank : 58)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

GOGA4_HUMAN
NC score	0.028587 (rank : 59)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	2034	Shared Neighborhood Hits	76
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGB1_HUMAN
NC score	0.028246 (rank : 60)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	2297	Shared Neighborhood Hits	73
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

DDX5_HUMAN
NC score	0.028055 (rank : 61)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.028033 (rank : 62)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

PLEC1_HUMAN
NC score	0.027990 (rank : 63)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	1326	Shared Neighborhood Hits	63
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SMC4_MOUSE
NC score	0.027812 (rank : 64)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	830	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

TXLNA_MOUSE
NC score	0.027796 (rank : 65)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	846	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TPR_HUMAN
NC score	0.027580 (rank : 66)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	1921	Shared Neighborhood Hits	73
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

DDX3Y_HUMAN
NC score	0.026722 (rank : 67)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	121	Shared Neighborhood Hits	21
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

NUMA1_HUMAN
NC score	0.026615 (rank : 68)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	1523	Shared Neighborhood Hits	63
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CNTRB_HUMAN
NC score	0.026312 (rank : 69)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

NOP14_MOUSE
NC score	0.026225 (rank : 70)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	324	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

CE290_HUMAN
NC score	0.025772 (rank : 71)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	1553	Shared Neighborhood Hits	64
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

TXLNA_HUMAN
NC score	0.025715 (rank : 72)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	982	Shared Neighborhood Hits	52
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TCRG1_MOUSE
NC score	0.025687 (rank : 73)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	947	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TCRG1_HUMAN
NC score	0.025670 (rank : 74)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	929	Shared Neighborhood Hits	46
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

PHF20_HUMAN
NC score	0.025557 (rank : 75)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	394	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

NTBP1_MOUSE
NC score	0.025514 (rank : 76)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	528	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

CCD27_HUMAN
NC score	0.025404 (rank : 77)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	594	Shared Neighborhood Hits	39
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD21_HUMAN
NC score	0.025379 (rank : 78)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	1228	Shared Neighborhood Hits	61
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

NEST_HUMAN
NC score	0.025088 (rank : 79)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	1305	Shared Neighborhood Hits	51
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

LIPA1_HUMAN
NC score	0.025065 (rank : 80)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	1294	Shared Neighborhood Hits	55
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

DYNA_HUMAN
NC score	0.024964 (rank : 81)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	1194	Shared Neighborhood Hits	59
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

NBN_HUMAN
NC score	0.024592 (rank : 82)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	226	Shared Neighborhood Hits	14
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

NIN_MOUSE
NC score	0.024507 (rank : 83)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	1376	Shared Neighborhood Hits	56
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

BICD1_MOUSE
NC score	0.024390 (rank : 84)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	837	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

PEPL_HUMAN
NC score	0.024137 (rank : 85)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	1141	Shared Neighborhood Hits	56
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

CENPE_HUMAN
NC score	0.023641 (rank : 86)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	2060	Shared Neighborhood Hits	73
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MPP8_HUMAN
NC score	0.023525 (rank : 87)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	948	Shared Neighborhood Hits	50
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

LEO1_MOUSE
NC score	0.023271 (rank : 88)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	946	Shared Neighborhood Hits	35
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

CCD45_HUMAN
NC score	0.022668 (rank : 89)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	525	Shared Neighborhood Hits	40
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

MYH10_MOUSE
NC score	0.022099 (rank : 90)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	1612	Shared Neighborhood Hits	68
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

GOGA5_HUMAN
NC score	0.021741 (rank : 91)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	1168	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

MYH10_HUMAN
NC score	0.021524 (rank : 92)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	1620	Shared Neighborhood Hits	67
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CENPK_MOUSE
NC score	0.021124 (rank : 93)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	149	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

GOGA1_MOUSE
NC score	0.020706 (rank : 94)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	994	Shared Neighborhood Hits	51
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MYH3_HUMAN
NC score	0.020374 (rank : 95)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	1660	Shared Neighborhood Hits	66
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH13_HUMAN
NC score	0.019928 (rank : 96)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	1504	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

AL2SA_HUMAN
NC score	0.019048 (rank : 97)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

IQGA1_HUMAN
NC score	0.018497 (rank : 98)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	250	Shared Neighborhood Hits	22
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

TP53B_HUMAN
NC score	0.018140 (rank : 99)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	413	Shared Neighborhood Hits	13
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

NOC2L_MOUSE
NC score	0.017688 (rank : 100)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WV70, Q8VE16	Gene names	Noc2l
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

RECQ1_MOUSE
NC score	0.017458 (rank : 101)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

IQGA1_MOUSE
NC score	0.017427 (rank : 102)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	219	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

LAMA2_HUMAN
NC score	0.017395 (rank : 103)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	1092	Shared Neighborhood Hits	43
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

STMN4_HUMAN
NC score	0.017337 (rank : 104)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	395	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
NC score	0.017334 (rank : 105)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	395	Shared Neighborhood Hits	31
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

LAMA2_MOUSE
NC score	0.017289 (rank : 106)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	1198	Shared Neighborhood Hits	40
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

PHF20_MOUSE
NC score	0.017129 (rank : 107)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	513	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

NF2L2_HUMAN
NC score	0.016882 (rank : 108)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

PLCB1_MOUSE
NC score	0.016122 (rank : 109)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	531	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

RIMB1_HUMAN
NC score	0.016119 (rank : 110)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	1479	Shared Neighborhood Hits	48
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NUCB1_HUMAN
NC score	0.015962 (rank : 111)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

ZN318_MOUSE
NC score	0.015096 (rank : 112)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	642	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

PI3R5_MOUSE
NC score	0.013176 (rank : 113)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SW28, Q3TU01, Q3UDZ2, Q8C215, Q8CGQ7	Gene names	Pik3r5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit).

UTP6_HUMAN
NC score	0.012222 (rank : 114)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYH9, Q8IX96, Q96BL2, Q9NQ91	Gene names	UTP6, C17orf40, HCA66, MHAT
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein) (Hepatocellular carcinoma-associated antigen 66).

ROCK1_MOUSE
NC score	0.011929 (rank : 115)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	2126	Shared Neighborhood Hits	61
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

A4_MOUSE
NC score	0.011536 (rank : 116)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

ROCK1_HUMAN
NC score	0.011370 (rank : 117)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	2000	Shared Neighborhood Hits	54
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

A4_HUMAN
NC score	0.011307 (rank : 118)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

PI3R5_HUMAN
NC score	0.010885 (rank : 119)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYR1, Q5G936, Q5G938, Q5G939, Q8IZ23, Q9Y2Y2	Gene names	PIK3R5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2).

TTC1_HUMAN
NC score	0.010351 (rank : 120)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	417	Shared Neighborhood Hits	25
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

RPTN_MOUSE
NC score	0.009656 (rank : 121)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	650	Shared Neighborhood Hits	20
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

ADA30_HUMAN
NC score	0.009591 (rank : 122)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	391	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

OGFR_MOUSE
NC score	0.009474 (rank : 123)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	584	Shared Neighborhood Hits	9
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

NF2L2_MOUSE
NC score	0.008711 (rank : 124)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	183	Shared Neighborhood Hits	6
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

FTS1_MOUSE
NC score	0.008169 (rank : 125)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q64362	Gene names	Fts, Fif, Ft1
Domain Architecture	No domain graphic available
Description	Fused toes protein (FT1).

MYO9B_MOUSE
NC score	0.008068 (rank : 126)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	311	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RAI1_HUMAN
NC score	0.007979 (rank : 127)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

BFSP2_MOUSE
NC score	0.007697 (rank : 128)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	423	Shared Neighborhood Hits	30
SwissProt Accessions	Q6NVD9, Q63832, Q6P5N4, Q8VDD6	Gene names	Bfsp2
Domain Architecture	No domain graphic available
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein).

FA47A_HUMAN
NC score	0.007171 (rank : 129)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	451	Shared Neighborhood Hits	6
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

NALP5_MOUSE
NC score	0.006651 (rank : 130)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	560	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

DIRA3_HUMAN
NC score	0.005630 (rank : 131)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	241	Shared Neighborhood Hits	2
SwissProt Accessions	O95661	Gene names	DIRAS3, ARHI, NOEY2, RHOI
Domain Architecture
Description	GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI).

ABC8A_MOUSE
NC score	0.005268 (rank : 132)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ITAM_HUMAN
NC score	0.004184 (rank : 133)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

F10A1_HUMAN
NC score	0.004165 (rank : 134)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	312	Shared Neighborhood Hits	10
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

MA2A1_MOUSE
NC score	0.004080 (rank : 135)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

ITA11_HUMAN
NC score	0.004034 (rank : 136)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKX5, Q8WYI8, Q9UKQ1	Gene names	ITGA11
Domain Architecture
Description	Integrin alpha-11 precursor.

ABCAA_HUMAN
NC score	0.003892 (rank : 137)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABCCB_HUMAN
NC score	0.003416 (rank : 138)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

AMFR2_HUMAN
NC score	0.003308 (rank : 139)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

NEK1_MOUSE
NC score	0.001689 (rank : 140)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	1311	Shared Neighborhood Hits	34
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

FOXN3_HUMAN
NC score	0.001161 (rank : 141)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

FBN3_HUMAN
NC score	0.001033 (rank : 142)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	543	Shared Neighborhood Hits	5
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

CP2CJ_HUMAN
NC score	0.000932 (rank : 143)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P33261, P33259, Q8WZB1, Q8WZB2	Gene names	CYP2C19
Domain Architecture
Description	Cytochrome P450 2C19 (EC 1.14.13.80) ((R)-limonene 6-monooxygenase) (EC 1.14.13.48) ((S)-limonene 6-monooxygenase) (EC 1.14.13.49) ((S)- limonene 7-monooxygenase) (CYPIIC19) (P450-11A) (Mephenytoin 4- hydroxylase) (CYPIIC17) (P450-254C).

LATS1_MOUSE
NC score	0.000190 (rank : 144)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	1027	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).