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Network neighborhood for query Sequence : DHX35_HUMAN

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DHX35_HUMAN
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DHX35_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

DHX8_HUMAN
θ value	6.7907e-165 (rank : 2)	NC score	0.985095 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

PRP16_HUMAN
θ value	4.71363e-158 (rank : 3)	NC score	0.979024 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

DHX33_MOUSE
θ value	1.67649e-155 (rank : 4)	NC score	0.988799 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX16_HUMAN
θ value	1.08667e-154 (rank : 5)	NC score	0.947677 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	356	Shared Neighborhood Hits	24
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DHX15_HUMAN
θ value	3.61748e-150 (rank : 6)	NC score	0.989409 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

DHX15_MOUSE
θ value	3.61748e-150 (rank : 7)	NC score	0.989269 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

DHX33_HUMAN
θ value	6.82227e-149 (rank : 8)	NC score	0.988144 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX40_MOUSE
θ value	1.0968e-122 (rank : 9)	NC score	0.981993 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

DHX40_HUMAN
θ value	5.44333e-122 (rank : 10)	NC score	0.982588 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

DHX34_MOUSE
θ value	8.77142e-88 (rank : 11)	NC score	0.953742 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	235	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX36_MOUSE
θ value	6.30065e-78 (rank : 12)	NC score	0.920299 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX36_HUMAN
θ value	1.60597e-73 (rank : 13)	NC score	0.925626 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX9_HUMAN
θ value	1.71981e-67 (rank : 14)	NC score	0.921342 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

DHX30_MOUSE
θ value	1.15359e-63 (rank : 15)	NC score	0.930301 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_HUMAN
θ value	1.96772e-63 (rank : 16)	NC score	0.930871 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX9_MOUSE
θ value	2.40537e-61 (rank : 17)	NC score	0.921284 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

DHX37_HUMAN
θ value	1.85029e-45 (rank : 18)	NC score	0.920904 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	133	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

DHX29_MOUSE
θ value	3.15612e-45 (rank : 19)	NC score	0.887368 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	103	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

DHX57_MOUSE
θ value	4.55743e-44 (rank : 20)	NC score	0.878300 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_HUMAN
θ value	1.01529e-43 (rank : 21)	NC score	0.879516 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX29_HUMAN
θ value	3.85808e-43 (rank : 22)	NC score	0.892782 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DHX34_HUMAN
θ value	1.08726e-37 (rank : 23)	NC score	0.934407 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

YTDC2_HUMAN
θ value	1.86753e-13 (rank : 24)	NC score	0.761638 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

DEN1A_MOUSE
θ value	0.62314 (rank : 25)	NC score	0.020084 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN1A_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.019512 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

MDR2_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.014380 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	108	Shared Neighborhood Hits	11
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

PNKP_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.029690 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

ABCA3_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.008198 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

ECE2_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.005798 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	O60344, Q96NX3, Q96NX4	Gene names	ECE2, KIAA0604
Domain Architecture
Description	Endothelin-converting enzyme 2 (EC 3.4.24.71) (ECE-2).

PMVK_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.015491 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q15126	Gene names	PMVK, PMKI
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).

MDR1_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.013581 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

RBGPR_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.009933 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BMG7, Q6PEU0, Q80TQ6, Q8BX72	Gene names	Rab3gap2, Kiaa0839
Domain Architecture	No domain graphic available
Description	Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase- activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP regulatory subunit) (RAB3-GAP150).

UAP56_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.004855 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	4.03905 (rank : 35)	NC score	0.004856 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

CSMD2_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.001916 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

GIMA5_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.006431 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q96F15, Q6IA75, Q96NE4, Q9NUK9	Gene names	GIMAP5, IAN4L1, IMAP3
Domain Architecture
Description	GTPase, IMAP family member 5 (Immunity-associated nucleotide 4-like 1 protein) (Immunity-associated protein 3) (IAN-5).

MDR3_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.013524 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

NID2_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.000459 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	456	Shared Neighborhood Hits	2
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

ABCB5_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.012552 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

ABCBB_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.012992 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

CHD6_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.001763 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	342	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

MDR1_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.012829 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.013029 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

MRP1_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.007836 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP1_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.008018 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

Hits sorted by NC score

DHX35_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

DHX15_HUMAN
NC score	0.989409 (rank : 2)	θ value	3.61748e-150 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

DHX15_MOUSE
NC score	0.989269 (rank : 3)	θ value	3.61748e-150 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

DHX33_MOUSE
NC score	0.988799 (rank : 4)	θ value	1.67649e-155 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX33_HUMAN
NC score	0.988144 (rank : 5)	θ value	6.82227e-149 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX8_HUMAN
NC score	0.985095 (rank : 6)	θ value	6.7907e-165 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

DHX40_HUMAN
NC score	0.982588 (rank : 7)	θ value	5.44333e-122 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

DHX40_MOUSE
NC score	0.981993 (rank : 8)	θ value	1.0968e-122 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

PRP16_HUMAN
NC score	0.979024 (rank : 9)	θ value	4.71363e-158 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

DHX34_MOUSE
NC score	0.953742 (rank : 10)	θ value	8.77142e-88 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	235	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX16_HUMAN
NC score	0.947677 (rank : 11)	θ value	1.08667e-154 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	356	Shared Neighborhood Hits	24
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DHX34_HUMAN
NC score	0.934407 (rank : 12)	θ value	1.08726e-37 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX30_HUMAN
NC score	0.930871 (rank : 13)	θ value	1.96772e-63 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_MOUSE
NC score	0.930301 (rank : 14)	θ value	1.15359e-63 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX36_HUMAN
NC score	0.925626 (rank : 15)	θ value	1.60597e-73 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX9_HUMAN
NC score	0.921342 (rank : 16)	θ value	1.71981e-67 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

DHX9_MOUSE
NC score	0.921284 (rank : 17)	θ value	2.40537e-61 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

DHX37_HUMAN
NC score	0.920904 (rank : 18)	θ value	1.85029e-45 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	133	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

DHX36_MOUSE
NC score	0.920299 (rank : 19)	θ value	6.30065e-78 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX29_HUMAN
NC score	0.892782 (rank : 20)	θ value	3.85808e-43 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DHX29_MOUSE
NC score	0.887368 (rank : 21)	θ value	3.15612e-45 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	103	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

DHX57_HUMAN
NC score	0.879516 (rank : 22)	θ value	1.01529e-43 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_MOUSE
NC score	0.878300 (rank : 23)	θ value	4.55743e-44 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

YTDC2_HUMAN
NC score	0.761638 (rank : 24)	θ value	1.86753e-13 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

PNKP_MOUSE
NC score	0.029690 (rank : 25)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

DEN1A_MOUSE
NC score	0.020084 (rank : 26)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN1A_HUMAN
NC score	0.019512 (rank : 27)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

PMVK_HUMAN
NC score	0.015491 (rank : 28)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q15126	Gene names	PMVK, PMKI
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).

MDR2_MOUSE
NC score	0.014380 (rank : 29)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	108	Shared Neighborhood Hits	11
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

MDR1_HUMAN
NC score	0.013581 (rank : 30)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_HUMAN
NC score	0.013524 (rank : 31)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

MDR3_MOUSE
NC score	0.013029 (rank : 32)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

ABCBB_MOUSE
NC score	0.012992 (rank : 33)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

MDR1_MOUSE
NC score	0.012829 (rank : 34)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

ABCB5_HUMAN
NC score	0.012552 (rank : 35)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

RBGPR_MOUSE
NC score	0.009933 (rank : 36)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BMG7, Q6PEU0, Q80TQ6, Q8BX72	Gene names	Rab3gap2, Kiaa0839
Domain Architecture	No domain graphic available
Description	Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase- activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP regulatory subunit) (RAB3-GAP150).

ABCA3_HUMAN
NC score	0.008198 (rank : 37)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

MRP1_MOUSE
NC score	0.008018 (rank : 38)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP1_HUMAN
NC score	0.007836 (rank : 39)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

GIMA5_HUMAN
NC score	0.006431 (rank : 40)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q96F15, Q6IA75, Q96NE4, Q9NUK9	Gene names	GIMAP5, IAN4L1, IMAP3
Domain Architecture
Description	GTPase, IMAP family member 5 (Immunity-associated nucleotide 4-like 1 protein) (Immunity-associated protein 3) (IAN-5).

ECE2_HUMAN
NC score	0.005798 (rank : 41)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	O60344, Q96NX3, Q96NX4	Gene names	ECE2, KIAA0604
Domain Architecture
Description	Endothelin-converting enzyme 2 (EC 3.4.24.71) (ECE-2).

UAP56_MOUSE
NC score	0.004856 (rank : 42)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

UAP56_HUMAN
NC score	0.004855 (rank : 43)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

CSMD2_HUMAN
NC score	0.001916 (rank : 44)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CHD6_HUMAN
NC score	0.001763 (rank : 45)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	342	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

NID2_HUMAN
NC score	0.000459 (rank : 46)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	456	Shared Neighborhood Hits	2
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).