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Network neighborhood for query Sequence : ABCAA_HUMAN

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ABCAA_HUMAN
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ABC8A_MOUSE
θ value	0 (rank : 1)	NC score	0.995446 (rank : 5)
Query Neighborhood Hits	123	Target Neighborhood Hits	115	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ABC8B_MOUSE
θ value	0 (rank : 2)	NC score	0.995271 (rank : 6)
Query Neighborhood Hits	123	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

ABCA5_HUMAN
θ value	0 (rank : 3)	NC score	0.987054 (rank : 10)
Query Neighborhood Hits	123	Target Neighborhood Hits	146	Shared Neighborhood Hits	91
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA5_MOUSE
θ value	0 (rank : 4)	NC score	0.987237 (rank : 9)
Query Neighborhood Hits	123	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA6_HUMAN
θ value	0 (rank : 5)	NC score	0.995958 (rank : 2)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA6_MOUSE
θ value	0 (rank : 6)	NC score	0.995201 (rank : 7)
Query Neighborhood Hits	123	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA8_HUMAN
θ value	0 (rank : 7)	NC score	0.993091 (rank : 8)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

ABCA9_HUMAN
θ value	0 (rank : 8)	NC score	0.995745 (rank : 3)
Query Neighborhood Hits	123	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCA9_MOUSE
θ value	0 (rank : 9)	NC score	0.995572 (rank : 4)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCAA_HUMAN
θ value	0 (rank : 10)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	123	Target Neighborhood Hits	123	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABCA3_MOUSE
θ value	3.56116e-89 (rank : 11)	NC score	0.918201 (rank : 11)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.

ABCA3_HUMAN
θ value	4.81303e-86 (rank : 12)	NC score	0.909718 (rank : 12)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

ABCA1_MOUSE
θ value	6.73165e-80 (rank : 13)	NC score	0.862913 (rank : 16)
Query Neighborhood Hits	123	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

ABCA1_HUMAN
θ value	1.26953e-78 (rank : 14)	NC score	0.860109 (rank : 19)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

ABCA2_HUMAN
θ value	5.33382e-77 (rank : 15)	NC score	0.882059 (rank : 13)
Query Neighborhood Hits	123	Target Neighborhood Hits	143	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA2_MOUSE
θ value	6.52014e-75 (rank : 16)	NC score	0.877318 (rank : 14)
Query Neighborhood Hits	123	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCAC_HUMAN
θ value	1.96316e-71 (rank : 17)	NC score	0.874072 (rank : 15)
Query Neighborhood Hits	123	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

ABCAD_HUMAN
θ value	5.34618e-69 (rank : 18)	NC score	0.857230 (rank : 21)
Query Neighborhood Hits	123	Target Neighborhood Hits	207	Shared Neighborhood Hits	86
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCA7_HUMAN
θ value	5.91091e-68 (rank : 19)	NC score	0.861970 (rank : 17)
Query Neighborhood Hits	123	Target Neighborhood Hits	144	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ABCAD_MOUSE
θ value	9.43692e-66 (rank : 20)	NC score	0.857687 (rank : 20)
Query Neighborhood Hits	123	Target Neighborhood Hits	150	Shared Neighborhood Hits	86
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCA7_MOUSE
θ value	2.74572e-65 (rank : 21)	NC score	0.860703 (rank : 18)
Query Neighborhood Hits	123	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

ABCA4_HUMAN
θ value	9.76566e-63 (rank : 22)	NC score	0.856824 (rank : 22)
Query Neighborhood Hits	123	Target Neighborhood Hits	116	Shared Neighborhood Hits	90
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

ABCA4_MOUSE
θ value	3.71096e-62 (rank : 23)	NC score	0.855508 (rank : 23)
Query Neighborhood Hits	123	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

ABCG8_HUMAN
θ value	1.47631e-18 (rank : 24)	NC score	0.717622 (rank : 24)
Query Neighborhood Hits	123	Target Neighborhood Hits	92	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H221	Gene names	ABCG8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG1_HUMAN
θ value	1.24977e-17 (rank : 25)	NC score	0.695954 (rank : 27)
Query Neighborhood Hits	123	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	P45844, Q86SU8, Q96L76, Q9BXK6, Q9BXK7, Q9BXK8, Q9BXK9, Q9BXL0, Q9BXL1, Q9BXL2, Q9BXL3, Q9BXL4	Gene names	ABCG1, ABC8, WHT1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG1_MOUSE
θ value	3.63628e-17 (rank : 26)	NC score	0.694792 (rank : 29)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q64343	Gene names	Abcg1, Abc8, Wht1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG8_MOUSE
θ value	5.25075e-16 (rank : 27)	NC score	0.695793 (rank : 28)
Query Neighborhood Hits	123	Target Neighborhood Hits	89	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBM0	Gene names	Abcg8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG4_HUMAN
θ value	8.95645e-16 (rank : 28)	NC score	0.692038 (rank : 30)
Query Neighborhood Hits	123	Target Neighborhood Hits	90	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H172	Gene names	ABCG4, WHITE2
Domain Architecture
Description	ATP-binding cassette sub-family G member 4.

ABCG2_HUMAN
θ value	3.40345e-15 (rank : 29)	NC score	0.680812 (rank : 31)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UNQ0, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64, Q8IX16, Q96LD6, Q96TA8, Q9BY73, Q9NUS0	Gene names	ABCG2, ABCP, BCRP, BCRP1, MXR
Domain Architecture
Description	ATP-binding cassette sub-family G member 2 (Placenta-specific ATP- binding cassette transporter) (Breast cancer resistance protein) (Mitoxantrone resistance-associated protein) (CDw338 antigen).

ABCG2_MOUSE
θ value	1.68911e-14 (rank : 30)	NC score	0.675298 (rank : 32)
Query Neighborhood Hits	123	Target Neighborhood Hits	92	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

MDR1_MOUSE
θ value	1.68911e-14 (rank : 31)	NC score	0.588181 (rank : 42)
Query Neighborhood Hits	123	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_MOUSE
θ value	6.41864e-14 (rank : 32)	NC score	0.587362 (rank : 43)
Query Neighborhood Hits	123	Target Neighborhood Hits	106	Shared Neighborhood Hits	88
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

MDR2_MOUSE
θ value	8.38298e-14 (rank : 33)	NC score	0.591307 (rank : 41)
Query Neighborhood Hits	123	Target Neighborhood Hits	108	Shared Neighborhood Hits	90
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

ABCG5_MOUSE
θ value	1.42992e-13 (rank : 34)	NC score	0.697850 (rank : 26)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	83
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

MDR1_HUMAN
θ value	1.86753e-13 (rank : 35)	NC score	0.585694 (rank : 45)
Query Neighborhood Hits	123	Target Neighborhood Hits	112	Shared Neighborhood Hits	90
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

ABCG5_HUMAN
θ value	4.16044e-13 (rank : 36)	NC score	0.709535 (rank : 25)
Query Neighborhood Hits	123	Target Neighborhood Hits	98	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H222	Gene names	ABCG5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

MDR3_HUMAN
θ value	5.43371e-13 (rank : 37)	NC score	0.583733 (rank : 46)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	90
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

TAP1_MOUSE
θ value	5.43371e-13 (rank : 38)	NC score	0.572981 (rank : 47)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	86
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

ABCB5_HUMAN
θ value	7.09661e-13 (rank : 39)	NC score	0.593537 (rank : 40)
Query Neighborhood Hits	123	Target Neighborhood Hits	102	Shared Neighborhood Hits	90
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

ABCB7_HUMAN
θ value	7.09661e-13 (rank : 40)	NC score	0.623351 (rank : 33)
Query Neighborhood Hits	123	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

MRP9_MOUSE
θ value	1.58096e-12 (rank : 41)	NC score	0.490389 (rank : 63)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

CFTR_HUMAN
θ value	4.59992e-12 (rank : 42)	NC score	0.531942 (rank : 54)
Query Neighborhood Hits	123	Target Neighborhood Hits	104	Shared Neighborhood Hits	89
SwissProt Accessions	P13569	Gene names	CFTR, ABCC7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

TAP1_HUMAN
θ value	4.59992e-12 (rank : 43)	NC score	0.586554 (rank : 44)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

ABCBA_MOUSE
θ value	6.00763e-12 (rank : 44)	NC score	0.599791 (rank : 38)
Query Neighborhood Hits	123	Target Neighborhood Hits	97	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JI39, Q542P7, Q9D0C7	Gene names	Abcb10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein).

ABCB6_HUMAN
θ value	1.33837e-11 (rank : 45)	NC score	0.606306 (rank : 35)
Query Neighborhood Hits	123	Target Neighborhood Hits	105	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NP58, O75542	Gene names	ABCB6, MTABC3
Domain Architecture
Description	ATP-binding cassette sub-family B member 6, mitochondrial precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat).

ABCBB_HUMAN
θ value	1.33837e-11 (rank : 46)	NC score	0.568249 (rank : 50)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

MRP6_HUMAN
θ value	6.64225e-11 (rank : 47)	NC score	0.485268 (rank : 66)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

MRP7_HUMAN
θ value	6.64225e-11 (rank : 48)	NC score	0.515520 (rank : 57)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q5T3U5, Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48	Gene names	ABCC10, MRP7, SIMRP7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

ABCBA_HUMAN
θ value	8.67504e-11 (rank : 49)	NC score	0.597087 (rank : 39)
Query Neighborhood Hits	123	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

ABCBB_MOUSE
θ value	8.67504e-11 (rank : 50)	NC score	0.569558 (rank : 49)
Query Neighborhood Hits	123	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

MRP9_HUMAN
θ value	8.67504e-11 (rank : 51)	NC score	0.487026 (rank : 65)
Query Neighborhood Hits	123	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	Q96J65, Q49AL2, Q8TAF0, Q8TEY2	Gene names	ABCC12, MRP9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP4_HUMAN
θ value	1.133e-10 (rank : 52)	NC score	0.494575 (rank : 62)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

CFTR_MOUSE
θ value	3.29651e-10 (rank : 53)	NC score	0.511459 (rank : 59)
Query Neighborhood Hits	123	Target Neighborhood Hits	115	Shared Neighborhood Hits	87
SwissProt Accessions	P26361, Q63893, Q63894, Q9JKQ6	Gene names	Cftr, Abcc7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

ABCB8_HUMAN
θ value	1.63604e-09 (rank : 54)	NC score	0.606405 (rank : 34)
Query Neighborhood Hits	123	Target Neighborhood Hits	91	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).

MRP7_MOUSE
θ value	2.79066e-09 (rank : 55)	NC score	0.499332 (rank : 61)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

MRP1_MOUSE
θ value	8.11959e-09 (rank : 56)	NC score	0.449620 (rank : 76)
Query Neighborhood Hits	123	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP6_MOUSE
θ value	1.38499e-08 (rank : 57)	NC score	0.472611 (rank : 67)
Query Neighborhood Hits	123	Target Neighborhood Hits	105	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

TAP2_HUMAN
θ value	3.08544e-08 (rank : 58)	NC score	0.572071 (rank : 48)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

ABCF2_HUMAN
θ value	6.87365e-08 (rank : 59)	NC score	0.515669 (rank : 56)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

ABCF2_MOUSE
θ value	6.87365e-08 (rank : 60)	NC score	0.517608 (rank : 55)
Query Neighborhood Hits	123	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

ABCF3_MOUSE
θ value	6.87365e-08 (rank : 61)	NC score	0.510194 (rank : 60)
Query Neighborhood Hits	123	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

MRP1_HUMAN
θ value	6.87365e-08 (rank : 62)	NC score	0.456386 (rank : 74)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	86
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

ABCB9_HUMAN
θ value	8.97725e-08 (rank : 63)	NC score	0.547567 (rank : 52)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).

TAP2_MOUSE
θ value	8.97725e-08 (rank : 64)	NC score	0.558858 (rank : 51)
Query Neighborhood Hits	123	Target Neighborhood Hits	93	Shared Neighborhood Hits	86
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

MRP2_HUMAN
θ value	1.53129e-07 (rank : 65)	NC score	0.469417 (rank : 69)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

MRP5_HUMAN
θ value	1.53129e-07 (rank : 66)	NC score	0.467118 (rank : 71)
Query Neighborhood Hits	123	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

ABCB9_MOUSE
θ value	3.41135e-07 (rank : 67)	NC score	0.546665 (rank : 53)
Query Neighborhood Hits	123	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

ABCF1_HUMAN
θ value	4.45536e-07 (rank : 68)	NC score	0.462676 (rank : 73)
Query Neighborhood Hits	123	Target Neighborhood Hits	343	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

MRP5_MOUSE
θ value	5.81887e-07 (rank : 69)	NC score	0.464638 (rank : 72)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

ABCF1_MOUSE
θ value	7.59969e-07 (rank : 70)	NC score	0.467611 (rank : 70)
Query Neighborhood Hits	123	Target Neighborhood Hits	321	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ABCD4_HUMAN
θ value	9.92553e-07 (rank : 71)	NC score	0.427566 (rank : 80)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	85
SwissProt Accessions	O14678	Gene names	ABCD4, PXMP1L
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

MRP3_HUMAN
θ value	9.92553e-07 (rank : 72)	NC score	0.445475 (rank : 77)
Query Neighborhood Hits	123	Target Neighborhood Hits	125	Shared Neighborhood Hits	88
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

MRP2_MOUSE
θ value	1.29631e-06 (rank : 73)	NC score	0.451084 (rank : 75)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

ABCE1_HUMAN
θ value	2.21117e-06 (rank : 74)	NC score	0.603370 (rank : 36)
Query Neighborhood Hits	123	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
θ value	2.21117e-06 (rank : 75)	NC score	0.603370 (rank : 37)
Query Neighborhood Hits	123	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

ABCG3_MOUSE
θ value	2.88788e-06 (rank : 76)	NC score	0.512983 (rank : 58)
Query Neighborhood Hits	123	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P81	Gene names	Abcg3
Domain Architecture
Description	ATP-binding cassette sub-family G member 3.

ABCCB_HUMAN
θ value	2.44474e-05 (rank : 77)	NC score	0.472080 (rank : 68)
Query Neighborhood Hits	123	Target Neighborhood Hits	118	Shared Neighborhood Hits	88
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

ABCF3_HUMAN
θ value	4.1701e-05 (rank : 78)	NC score	0.488676 (rank : 64)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCD4_MOUSE
θ value	5.44631e-05 (rank : 79)	NC score	0.380949 (rank : 82)
Query Neighborhood Hits	123	Target Neighborhood Hits	94	Shared Neighborhood Hits	81
SwissProt Accessions	O89016	Gene names	Abcd4, Pxmp1l
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCC9_HUMAN
θ value	0.000121331 (rank : 80)	NC score	0.430942 (rank : 79)
Query Neighborhood Hits	123	Target Neighborhood Hits	108	Shared Neighborhood Hits	88
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

ABCC9_MOUSE
θ value	0.000121331 (rank : 81)	NC score	0.441338 (rank : 78)
Query Neighborhood Hits	123	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

ABCC8_HUMAN
θ value	0.000786445 (rank : 82)	NC score	0.407429 (rank : 81)
Query Neighborhood Hits	123	Target Neighborhood Hits	118	Shared Neighborhood Hits	87
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

MDN1_HUMAN
θ value	0.00509761 (rank : 83)	NC score	0.097459 (rank : 90)
Query Neighborhood Hits	123	Target Neighborhood Hits	662	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

AT2A1_HUMAN
θ value	0.0252991 (rank : 84)	NC score	0.018088 (rank : 93)
Query Neighborhood Hits	123	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	O14983, O14984	Gene names	ATP2A1
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (EC 3.6.3.8) (Calcium pump 1) (SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

ABCD3_MOUSE
θ value	0.0563607 (rank : 85)	NC score	0.262648 (rank : 85)
Query Neighborhood Hits	123	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	P55096	Gene names	Abcd3, Pmp70, Pxmp1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) (PMP68).

ABCD2_HUMAN
θ value	0.0961366 (rank : 86)	NC score	0.249080 (rank : 86)
Query Neighborhood Hits	123	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UBJ2, Q13210	Gene names	ABCD2, ALD1, ALDL1, ALDR, ALDRP
Domain Architecture
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein) (hALDR) (Adrenoleukodystrophy-like 1).

ABCD3_HUMAN
θ value	0.0961366 (rank : 87)	NC score	0.271730 (rank : 83)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	P28288, Q15271, Q9H529	Gene names	ABCD3, PMP70, PXMP1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70).

ABCD2_MOUSE
θ value	0.21417 (rank : 88)	NC score	0.246321 (rank : 87)
Query Neighborhood Hits	123	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	Q61285, Q8BQ63, Q8C4B6	Gene names	Abcd2, Aldr
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein).

AT2A1_MOUSE
θ value	0.365318 (rank : 89)	NC score	0.016094 (rank : 94)
Query Neighborhood Hits	123	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R429	Gene names	Atp2a1
Domain Architecture	No domain graphic available
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (EC 3.6.3.8) (Calcium pump 1) (SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

MRGX1_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.006900 (rank : 108)
Query Neighborhood Hits	123	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LB2, Q8TDD8, Q8TDD9	Gene names	MRGPRX1, MRGX1, SNSR3, SNSR4
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member X1 (Sensory neuron- specific G-protein coupled receptor 3/4).

AT2A2_HUMAN
θ value	0.47712 (rank : 91)	NC score	0.015583 (rank : 95)
Query Neighborhood Hits	123	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	P16615, P16614	Gene names	ATP2A2, ATP2B
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (EC 3.6.3.8) (Calcium pump 2) (SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

AT2A2_MOUSE
θ value	0.47712 (rank : 92)	NC score	0.015571 (rank : 96)
Query Neighborhood Hits	123	Target Neighborhood Hits	68	Shared Neighborhood Hits	5
SwissProt Accessions	O55143, Q9R2A9, Q9WUT5	Gene names	Atp2a2
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (EC 3.6.3.8) (Calcium pump 2) (SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

MRGX4_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.006221 (rank : 113)
Query Neighborhood Hits	123	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LA9, Q3KNU3, Q3KNU4, Q502W0, Q8TDD6, Q8TDD7	Gene names	MRGPRX4, MRGX4, SNSR5, SNSR6
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member X4 (Sensory neuron- specific G-protein coupled receptor 5/6).

BRE1A_HUMAN
θ value	1.06291 (rank : 94)	NC score	0.003772 (rank : 118)
Query Neighborhood Hits	123	Target Neighborhood Hits	1071	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.003980 (rank : 116)
Query Neighborhood Hits	123	Target Neighborhood Hits	1025	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CARD4_MOUSE
θ value	1.06291 (rank : 96)	NC score	0.012417 (rank : 99)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CCDC5_HUMAN
θ value	1.06291 (rank : 97)	NC score	0.014698 (rank : 98)
Query Neighborhood Hits	123	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q96CS2, Q8N837	Gene names	CCDC5, HEIC
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5 (Enhancer of invasion-cluster) (HEI-C).

NCKX2_HUMAN
θ value	1.38821 (rank : 98)	NC score	0.008554 (rank : 103)
Query Neighborhood Hits	123	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UI40, Q9NTN5, Q9NZQ4	Gene names	SLC24A2, NCKX2
Domain Architecture
Description	Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).

CLCN1_HUMAN
θ value	1.81305 (rank : 99)	NC score	0.004994 (rank : 114)
Query Neighborhood Hits	123	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

MRGX3_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.006867 (rank : 109)
Query Neighborhood Hits	123	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LB0, Q8TDE0, Q8TDE1	Gene names	MRGPRX3, MRGX3, SNSR1, SNSR2
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member X3 (Sensory neuron- specific G-protein coupled receptor 1/2).

I17RB_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.009387 (rank : 102)
Query Neighborhood Hits	123	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIP3, Q9JIP2	Gene names	Il17rb, Evi27, Il17br
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor B precursor (IL-17 receptor B) (IL-17RB) (Interleukin-17B receptor) (IL-17B receptor) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (IL-17ER).

TA2R7_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.001413 (rank : 120)
Query Neighborhood Hits	123	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYW3	Gene names	TAS2R7
Domain Architecture
Description	Taste receptor type 2 member 7 (T2R7) (Taste receptor family B member 4) (TRB4).

TM9S4_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.006644 (rank : 110)
Query Neighborhood Hits	123	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q92544, Q9NUA3	Gene names	TM9SF4, KIAA0255
Domain Architecture
Description	Transmembrane 9 superfamily protein member 4.

DRP2_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.004574 (rank : 115)
Query Neighborhood Hits	123	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

ABCD1_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.240442 (rank : 88)
Query Neighborhood Hits	123	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	P48410, Q9QY41, Q9QZ32	Gene names	Abcd1, Ald, Aldgh
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

EEA1_HUMAN
θ value	5.27518 (rank : 106)	NC score	-0.004084 (rank : 123)
Query Neighborhood Hits	123	Target Neighborhood Hits	1796	Shared Neighborhood Hits	15
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

SNG1_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.008088 (rank : 104)
Query Neighborhood Hits	123	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O55100, Q543Y5, Q9DCB0	Gene names	Syngr1
Domain Architecture
Description	Synaptogyrin-1.

ACM2_HUMAN
θ value	6.88961 (rank : 108)	NC score	-0.005660 (rank : 125)
Query Neighborhood Hits	123	Target Neighborhood Hits	930	Shared Neighborhood Hits	2
SwissProt Accessions	P08172, Q9P1X9	Gene names	CHRM2
Domain Architecture
Description	Muscarinic acetylcholine receptor M2.

AKAP9_HUMAN
θ value	6.88961 (rank : 109)	NC score	-0.004228 (rank : 124)
Query Neighborhood Hits	123	Target Neighborhood Hits	1710	Shared Neighborhood Hits	14
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CASP_MOUSE
θ value	6.88961 (rank : 110)	NC score	-0.001650 (rank : 121)
Query Neighborhood Hits	123	Target Neighborhood Hits	1152	Shared Neighborhood Hits	12
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

DHX29_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.003892 (rank : 117)
Query Neighborhood Hits	123	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

IIGP1_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.015031 (rank : 97)
Query Neighborhood Hits	123	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ85, Q9Z1M3	Gene names	Iigp1
Domain Architecture	No domain graphic available
Description	Interferon-inducible GTPase (EC 3.6.5.-).

K0528_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.003631 (rank : 119)
Query Neighborhood Hits	123	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

CASC5_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.007292 (rank : 105)
Query Neighborhood Hits	123	Target Neighborhood Hits	376	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CASC5_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.006536 (rank : 111)
Query Neighborhood Hits	123	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

DEFM_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.010013 (rank : 101)
Query Neighborhood Hits	123	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBH1, Q8WUN6	Gene names	PDF, PDF1A
Domain Architecture
Description	Peptide deformylase, mitochondrial precursor (EC 3.5.1.88) (Polypeptide deformylase).

MACF4_HUMAN
θ value	8.99809 (rank : 117)	NC score	-0.002571 (rank : 122)
Query Neighborhood Hits	123	Target Neighborhood Hits	1321	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

PEO1_MOUSE
θ value	8.99809 (rank : 118)	NC score	0.011564 (rank : 100)
Query Neighborhood Hits	123	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

RAD50_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.029096 (rank : 92)
Query Neighborhood Hits	123	Target Neighborhood Hits	1317	Shared Neighborhood Hits	45
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.029826 (rank : 91)
Query Neighborhood Hits	123	Target Neighborhood Hits	1366	Shared Neighborhood Hits	46
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SACA1_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.006224 (rank : 112)
Query Neighborhood Hits	123	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DA48	Gene names	Spaca1
Domain Architecture	No domain graphic available
Description	Sperm acrosome membrane-associated protein 1 precursor.

VIAAT_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.007038 (rank : 107)
Query Neighborhood Hits	123	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H598, Q8N489	Gene names	SLC32A1, VGAT, VIAAT
Domain Architecture
Description	Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Vesicular GABA transporter) (hVIAAT) (Solute carrier family 32 member 1).

VIAAT_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.007050 (rank : 106)
Query Neighborhood Hits	123	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O35633	Gene names	Slc32a1, Vgat, Viaat
Domain Architecture
Description	Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Vesicular GABA transporter) (mVIAAT) (mVGAT) (Solute carrier family 32 member 1).

ABCCD_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.150756 (rank : 89)
Query Neighborhood Hits	123	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NSE7, Q8N6A4, Q8N6A5	Gene names	ABCC13, C21orf73, PRED6
Domain Architecture
Description	Putative ATP-binding cassette transporter C13.

ABCD1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.265599 (rank : 84)
Query Neighborhood Hits	123	Target Neighborhood Hits	91	Shared Neighborhood Hits	77
SwissProt Accessions	P33897, Q6GTZ2	Gene names	ABCD1, ALD
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

Hits sorted by NC score

ABCAA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 10)
Query Neighborhood Hits	123	Target Neighborhood Hits	123	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABCA6_HUMAN
NC score	0.995958 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA9_HUMAN
NC score	0.995745 (rank : 3)	θ value	0 (rank : 8)
Query Neighborhood Hits	123	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCA9_MOUSE
NC score	0.995572 (rank : 4)	θ value	0 (rank : 9)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABC8A_MOUSE
NC score	0.995446 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	123	Target Neighborhood Hits	115	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ABC8B_MOUSE
NC score	0.995271 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	123	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

ABCA6_MOUSE
NC score	0.995201 (rank : 7)	θ value	0 (rank : 6)
Query Neighborhood Hits	123	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA8_HUMAN
NC score	0.993091 (rank : 8)	θ value	0 (rank : 7)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

ABCA5_MOUSE
NC score	0.987237 (rank : 9)	θ value	0 (rank : 4)
Query Neighborhood Hits	123	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA5_HUMAN
NC score	0.987054 (rank : 10)	θ value	0 (rank : 3)
Query Neighborhood Hits	123	Target Neighborhood Hits	146	Shared Neighborhood Hits	91
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA3_MOUSE
NC score	0.918201 (rank : 11)	θ value	3.56116e-89 (rank : 11)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.

ABCA3_HUMAN
NC score	0.909718 (rank : 12)	θ value	4.81303e-86 (rank : 12)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

ABCA2_HUMAN
NC score	0.882059 (rank : 13)	θ value	5.33382e-77 (rank : 15)
Query Neighborhood Hits	123	Target Neighborhood Hits	143	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA2_MOUSE
NC score	0.877318 (rank : 14)	θ value	6.52014e-75 (rank : 16)
Query Neighborhood Hits	123	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCAC_HUMAN
NC score	0.874072 (rank : 15)	θ value	1.96316e-71 (rank : 17)
Query Neighborhood Hits	123	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

ABCA1_MOUSE
NC score	0.862913 (rank : 16)	θ value	6.73165e-80 (rank : 13)
Query Neighborhood Hits	123	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

ABCA7_HUMAN
NC score	0.861970 (rank : 17)	θ value	5.91091e-68 (rank : 19)
Query Neighborhood Hits	123	Target Neighborhood Hits	144	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ABCA7_MOUSE
NC score	0.860703 (rank : 18)	θ value	2.74572e-65 (rank : 21)
Query Neighborhood Hits	123	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

ABCA1_HUMAN
NC score	0.860109 (rank : 19)	θ value	1.26953e-78 (rank : 14)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

ABCAD_MOUSE
NC score	0.857687 (rank : 20)	θ value	9.43692e-66 (rank : 20)
Query Neighborhood Hits	123	Target Neighborhood Hits	150	Shared Neighborhood Hits	86
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCAD_HUMAN
NC score	0.857230 (rank : 21)	θ value	5.34618e-69 (rank : 18)
Query Neighborhood Hits	123	Target Neighborhood Hits	207	Shared Neighborhood Hits	86
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCA4_HUMAN
NC score	0.856824 (rank : 22)	θ value	9.76566e-63 (rank : 22)
Query Neighborhood Hits	123	Target Neighborhood Hits	116	Shared Neighborhood Hits	90
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

ABCA4_MOUSE
NC score	0.855508 (rank : 23)	θ value	3.71096e-62 (rank : 23)
Query Neighborhood Hits	123	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

ABCG8_HUMAN
NC score	0.717622 (rank : 24)	θ value	1.47631e-18 (rank : 24)
Query Neighborhood Hits	123	Target Neighborhood Hits	92	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H221	Gene names	ABCG8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG5_HUMAN
NC score	0.709535 (rank : 25)	θ value	4.16044e-13 (rank : 36)
Query Neighborhood Hits	123	Target Neighborhood Hits	98	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H222	Gene names	ABCG5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCG5_MOUSE
NC score	0.697850 (rank : 26)	θ value	1.42992e-13 (rank : 34)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	83
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCG1_HUMAN
NC score	0.695954 (rank : 27)	θ value	1.24977e-17 (rank : 25)
Query Neighborhood Hits	123	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	P45844, Q86SU8, Q96L76, Q9BXK6, Q9BXK7, Q9BXK8, Q9BXK9, Q9BXL0, Q9BXL1, Q9BXL2, Q9BXL3, Q9BXL4	Gene names	ABCG1, ABC8, WHT1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG8_MOUSE
NC score	0.695793 (rank : 28)	θ value	5.25075e-16 (rank : 27)
Query Neighborhood Hits	123	Target Neighborhood Hits	89	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBM0	Gene names	Abcg8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG1_MOUSE
NC score	0.694792 (rank : 29)	θ value	3.63628e-17 (rank : 26)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q64343	Gene names	Abcg1, Abc8, Wht1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG4_HUMAN
NC score	0.692038 (rank : 30)	θ value	8.95645e-16 (rank : 28)
Query Neighborhood Hits	123	Target Neighborhood Hits	90	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H172	Gene names	ABCG4, WHITE2
Domain Architecture
Description	ATP-binding cassette sub-family G member 4.

ABCG2_HUMAN
NC score	0.680812 (rank : 31)	θ value	3.40345e-15 (rank : 29)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UNQ0, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64, Q8IX16, Q96LD6, Q96TA8, Q9BY73, Q9NUS0	Gene names	ABCG2, ABCP, BCRP, BCRP1, MXR
Domain Architecture
Description	ATP-binding cassette sub-family G member 2 (Placenta-specific ATP- binding cassette transporter) (Breast cancer resistance protein) (Mitoxantrone resistance-associated protein) (CDw338 antigen).

ABCG2_MOUSE
NC score	0.675298 (rank : 32)	θ value	1.68911e-14 (rank : 30)
Query Neighborhood Hits	123	Target Neighborhood Hits	92	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

ABCB7_HUMAN
NC score	0.623351 (rank : 33)	θ value	7.09661e-13 (rank : 40)
Query Neighborhood Hits	123	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

ABCB8_HUMAN
NC score	0.606405 (rank : 34)	θ value	1.63604e-09 (rank : 54)
Query Neighborhood Hits	123	Target Neighborhood Hits	91	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).

ABCB6_HUMAN
NC score	0.606306 (rank : 35)	θ value	1.33837e-11 (rank : 45)
Query Neighborhood Hits	123	Target Neighborhood Hits	105	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NP58, O75542	Gene names	ABCB6, MTABC3
Domain Architecture
Description	ATP-binding cassette sub-family B member 6, mitochondrial precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat).

ABCE1_HUMAN
NC score	0.603370 (rank : 36)	θ value	2.21117e-06 (rank : 74)
Query Neighborhood Hits	123	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
NC score	0.603370 (rank : 37)	θ value	2.21117e-06 (rank : 75)
Query Neighborhood Hits	123	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

ABCBA_MOUSE
NC score	0.599791 (rank : 38)	θ value	6.00763e-12 (rank : 44)
Query Neighborhood Hits	123	Target Neighborhood Hits	97	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JI39, Q542P7, Q9D0C7	Gene names	Abcb10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein).

ABCBA_HUMAN
NC score	0.597087 (rank : 39)	θ value	8.67504e-11 (rank : 49)
Query Neighborhood Hits	123	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

ABCB5_HUMAN
NC score	0.593537 (rank : 40)	θ value	7.09661e-13 (rank : 39)
Query Neighborhood Hits	123	Target Neighborhood Hits	102	Shared Neighborhood Hits	90
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

MDR2_MOUSE
NC score	0.591307 (rank : 41)	θ value	8.38298e-14 (rank : 33)
Query Neighborhood Hits	123	Target Neighborhood Hits	108	Shared Neighborhood Hits	90
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

MDR1_MOUSE
NC score	0.588181 (rank : 42)	θ value	1.68911e-14 (rank : 31)
Query Neighborhood Hits	123	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_MOUSE
NC score	0.587362 (rank : 43)	θ value	6.41864e-14 (rank : 32)
Query Neighborhood Hits	123	Target Neighborhood Hits	106	Shared Neighborhood Hits	88
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

TAP1_HUMAN
NC score	0.586554 (rank : 44)	θ value	4.59992e-12 (rank : 43)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

MDR1_HUMAN
NC score	0.585694 (rank : 45)	θ value	1.86753e-13 (rank : 35)
Query Neighborhood Hits	123	Target Neighborhood Hits	112	Shared Neighborhood Hits	90
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_HUMAN
NC score	0.583733 (rank : 46)	θ value	5.43371e-13 (rank : 37)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	90
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

TAP1_MOUSE
NC score	0.572981 (rank : 47)	θ value	5.43371e-13 (rank : 38)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	86
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

TAP2_HUMAN
NC score	0.572071 (rank : 48)	θ value	3.08544e-08 (rank : 58)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

ABCBB_MOUSE
NC score	0.569558 (rank : 49)	θ value	8.67504e-11 (rank : 50)
Query Neighborhood Hits	123	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

ABCBB_HUMAN
NC score	0.568249 (rank : 50)	θ value	1.33837e-11 (rank : 46)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

TAP2_MOUSE
NC score	0.558858 (rank : 51)	θ value	8.97725e-08 (rank : 64)
Query Neighborhood Hits	123	Target Neighborhood Hits	93	Shared Neighborhood Hits	86
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

ABCB9_HUMAN
NC score	0.547567 (rank : 52)	θ value	8.97725e-08 (rank : 63)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).

ABCB9_MOUSE
NC score	0.546665 (rank : 53)	θ value	3.41135e-07 (rank : 67)
Query Neighborhood Hits	123	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

CFTR_HUMAN
NC score	0.531942 (rank : 54)	θ value	4.59992e-12 (rank : 42)
Query Neighborhood Hits	123	Target Neighborhood Hits	104	Shared Neighborhood Hits	89
SwissProt Accessions	P13569	Gene names	CFTR, ABCC7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

ABCF2_MOUSE
NC score	0.517608 (rank : 55)	θ value	6.87365e-08 (rank : 60)
Query Neighborhood Hits	123	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

ABCF2_HUMAN
NC score	0.515669 (rank : 56)	θ value	6.87365e-08 (rank : 59)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

MRP7_HUMAN
NC score	0.515520 (rank : 57)	θ value	6.64225e-11 (rank : 48)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q5T3U5, Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48	Gene names	ABCC10, MRP7, SIMRP7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

ABCG3_MOUSE
NC score	0.512983 (rank : 58)	θ value	2.88788e-06 (rank : 76)
Query Neighborhood Hits	123	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P81	Gene names	Abcg3
Domain Architecture
Description	ATP-binding cassette sub-family G member 3.

CFTR_MOUSE
NC score	0.511459 (rank : 59)	θ value	3.29651e-10 (rank : 53)
Query Neighborhood Hits	123	Target Neighborhood Hits	115	Shared Neighborhood Hits	87
SwissProt Accessions	P26361, Q63893, Q63894, Q9JKQ6	Gene names	Cftr, Abcc7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

ABCF3_MOUSE
NC score	0.510194 (rank : 60)	θ value	6.87365e-08 (rank : 61)
Query Neighborhood Hits	123	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

MRP7_MOUSE
NC score	0.499332 (rank : 61)	θ value	2.79066e-09 (rank : 55)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

MRP4_HUMAN
NC score	0.494575 (rank : 62)	θ value	1.133e-10 (rank : 52)
Query Neighborhood Hits	123	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

MRP9_MOUSE
NC score	0.490389 (rank : 63)	θ value	1.58096e-12 (rank : 41)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

ABCF3_HUMAN
NC score	0.488676 (rank : 64)	θ value	4.1701e-05 (rank : 78)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

MRP9_HUMAN
NC score	0.487026 (rank : 65)	θ value	8.67504e-11 (rank : 51)
Query Neighborhood Hits	123	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	Q96J65, Q49AL2, Q8TAF0, Q8TEY2	Gene names	ABCC12, MRP9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP6_HUMAN
NC score	0.485268 (rank : 66)	θ value	6.64225e-11 (rank : 47)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

MRP6_MOUSE
NC score	0.472611 (rank : 67)	θ value	1.38499e-08 (rank : 57)
Query Neighborhood Hits	123	Target Neighborhood Hits	105	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

ABCCB_HUMAN
NC score	0.472080 (rank : 68)	θ value	2.44474e-05 (rank : 77)
Query Neighborhood Hits	123	Target Neighborhood Hits	118	Shared Neighborhood Hits	88
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

MRP2_HUMAN
NC score	0.469417 (rank : 69)	θ value	1.53129e-07 (rank : 65)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

ABCF1_MOUSE
NC score	0.467611 (rank : 70)	θ value	7.59969e-07 (rank : 70)
Query Neighborhood Hits	123	Target Neighborhood Hits	321	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

MRP5_HUMAN
NC score	0.467118 (rank : 71)	θ value	1.53129e-07 (rank : 66)
Query Neighborhood Hits	123	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

MRP5_MOUSE
NC score	0.464638 (rank : 72)	θ value	5.81887e-07 (rank : 69)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

ABCF1_HUMAN
NC score	0.462676 (rank : 73)	θ value	4.45536e-07 (rank : 68)
Query Neighborhood Hits	123	Target Neighborhood Hits	343	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

MRP1_HUMAN
NC score	0.456386 (rank : 74)	θ value	6.87365e-08 (rank : 62)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	86
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP2_MOUSE
NC score	0.451084 (rank : 75)	θ value	1.29631e-06 (rank : 73)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

MRP1_MOUSE
NC score	0.449620 (rank : 76)	θ value	8.11959e-09 (rank : 56)
Query Neighborhood Hits	123	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP3_HUMAN
NC score	0.445475 (rank : 77)	θ value	9.92553e-07 (rank : 72)
Query Neighborhood Hits	123	Target Neighborhood Hits	125	Shared Neighborhood Hits	88
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

ABCC9_MOUSE
NC score	0.441338 (rank : 78)	θ value	0.000121331 (rank : 81)
Query Neighborhood Hits	123	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

ABCC9_HUMAN
NC score	0.430942 (rank : 79)	θ value	0.000121331 (rank : 80)
Query Neighborhood Hits	123	Target Neighborhood Hits	108	Shared Neighborhood Hits	88
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

ABCD4_HUMAN
NC score	0.427566 (rank : 80)	θ value	9.92553e-07 (rank : 71)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	85
SwissProt Accessions	O14678	Gene names	ABCD4, PXMP1L
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCC8_HUMAN
NC score	0.407429 (rank : 81)	θ value	0.000786445 (rank : 82)
Query Neighborhood Hits	123	Target Neighborhood Hits	118	Shared Neighborhood Hits	87
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

ABCD4_MOUSE
NC score	0.380949 (rank : 82)	θ value	5.44631e-05 (rank : 79)
Query Neighborhood Hits	123	Target Neighborhood Hits	94	Shared Neighborhood Hits	81
SwissProt Accessions	O89016	Gene names	Abcd4, Pxmp1l
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCD3_HUMAN
NC score	0.271730 (rank : 83)	θ value	0.0961366 (rank : 87)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	P28288, Q15271, Q9H529	Gene names	ABCD3, PMP70, PXMP1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70).

ABCD1_HUMAN
NC score	0.265599 (rank : 84)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	123	Target Neighborhood Hits	91	Shared Neighborhood Hits	77
SwissProt Accessions	P33897, Q6GTZ2	Gene names	ABCD1, ALD
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCD3_MOUSE
NC score	0.262648 (rank : 85)	θ value	0.0563607 (rank : 85)
Query Neighborhood Hits	123	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	P55096	Gene names	Abcd3, Pmp70, Pxmp1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) (PMP68).

ABCD2_HUMAN
NC score	0.249080 (rank : 86)	θ value	0.0961366 (rank : 86)
Query Neighborhood Hits	123	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UBJ2, Q13210	Gene names	ABCD2, ALD1, ALDL1, ALDR, ALDRP
Domain Architecture
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein) (hALDR) (Adrenoleukodystrophy-like 1).

ABCD2_MOUSE
NC score	0.246321 (rank : 87)	θ value	0.21417 (rank : 88)
Query Neighborhood Hits	123	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	Q61285, Q8BQ63, Q8C4B6	Gene names	Abcd2, Aldr
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein).

ABCD1_MOUSE
NC score	0.240442 (rank : 88)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	123	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	P48410, Q9QY41, Q9QZ32	Gene names	Abcd1, Ald, Aldgh
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCCD_HUMAN
NC score	0.150756 (rank : 89)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	123	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NSE7, Q8N6A4, Q8N6A5	Gene names	ABCC13, C21orf73, PRED6
Domain Architecture
Description	Putative ATP-binding cassette transporter C13.

MDN1_HUMAN
NC score	0.097459 (rank : 90)	θ value	0.00509761 (rank : 83)
Query Neighborhood Hits	123	Target Neighborhood Hits	662	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RAD50_MOUSE
NC score	0.029826 (rank : 91)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	123	Target Neighborhood Hits	1366	Shared Neighborhood Hits	46
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RAD50_HUMAN
NC score	0.029096 (rank : 92)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	123	Target Neighborhood Hits	1317	Shared Neighborhood Hits	45
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

AT2A1_HUMAN
NC score	0.018088 (rank : 93)	θ value	0.0252991 (rank : 84)
Query Neighborhood Hits	123	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	O14983, O14984	Gene names	ATP2A1
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (EC 3.6.3.8) (Calcium pump 1) (SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

AT2A1_MOUSE
NC score	0.016094 (rank : 94)	θ value	0.365318 (rank : 89)
Query Neighborhood Hits	123	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R429	Gene names	Atp2a1
Domain Architecture	No domain graphic available
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (EC 3.6.3.8) (Calcium pump 1) (SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

AT2A2_HUMAN
NC score	0.015583 (rank : 95)	θ value	0.47712 (rank : 91)
Query Neighborhood Hits	123	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	P16615, P16614	Gene names	ATP2A2, ATP2B
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (EC 3.6.3.8) (Calcium pump 2) (SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

AT2A2_MOUSE
NC score	0.015571 (rank : 96)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	123	Target Neighborhood Hits	68	Shared Neighborhood Hits	5
SwissProt Accessions	O55143, Q9R2A9, Q9WUT5	Gene names	Atp2a2
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (EC 3.6.3.8) (Calcium pump 2) (SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

IIGP1_MOUSE
NC score	0.015031 (rank : 97)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	123	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ85, Q9Z1M3	Gene names	Iigp1
Domain Architecture	No domain graphic available
Description	Interferon-inducible GTPase (EC 3.6.5.-).

CCDC5_HUMAN
NC score	0.014698 (rank : 98)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	123	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q96CS2, Q8N837	Gene names	CCDC5, HEIC
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5 (Enhancer of invasion-cluster) (HEI-C).

CARD4_MOUSE
NC score	0.012417 (rank : 99)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

PEO1_MOUSE
NC score	0.011564 (rank : 100)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	123	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

DEFM_HUMAN
NC score	0.010013 (rank : 101)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	123	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBH1, Q8WUN6	Gene names	PDF, PDF1A
Domain Architecture
Description	Peptide deformylase, mitochondrial precursor (EC 3.5.1.88) (Polypeptide deformylase).

I17RB_MOUSE
NC score	0.009387 (rank : 102)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	123	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIP3, Q9JIP2	Gene names	Il17rb, Evi27, Il17br
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor B precursor (IL-17 receptor B) (IL-17RB) (Interleukin-17B receptor) (IL-17B receptor) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (IL-17ER).

NCKX2_HUMAN
NC score	0.008554 (rank : 103)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	123	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UI40, Q9NTN5, Q9NZQ4	Gene names	SLC24A2, NCKX2
Domain Architecture
Description	Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).

SNG1_MOUSE
NC score	0.008088 (rank : 104)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	123	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O55100, Q543Y5, Q9DCB0	Gene names	Syngr1
Domain Architecture
Description	Synaptogyrin-1.

CASC5_HUMAN
NC score	0.007292 (rank : 105)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	123	Target Neighborhood Hits	376	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

VIAAT_MOUSE
NC score	0.007050 (rank : 106)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	123	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O35633	Gene names	Slc32a1, Vgat, Viaat
Domain Architecture
Description	Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Vesicular GABA transporter) (mVIAAT) (mVGAT) (Solute carrier family 32 member 1).

VIAAT_HUMAN
NC score	0.007038 (rank : 107)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	123	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H598, Q8N489	Gene names	SLC32A1, VGAT, VIAAT
Domain Architecture
Description	Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Vesicular GABA transporter) (hVIAAT) (Solute carrier family 32 member 1).

MRGX1_HUMAN
NC score	0.006900 (rank : 108)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	123	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LB2, Q8TDD8, Q8TDD9	Gene names	MRGPRX1, MRGX1, SNSR3, SNSR4
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member X1 (Sensory neuron- specific G-protein coupled receptor 3/4).

MRGX3_HUMAN
NC score	0.006867 (rank : 109)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	123	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LB0, Q8TDE0, Q8TDE1	Gene names	MRGPRX3, MRGX3, SNSR1, SNSR2
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member X3 (Sensory neuron- specific G-protein coupled receptor 1/2).

TM9S4_HUMAN
NC score	0.006644 (rank : 110)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	123	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q92544, Q9NUA3	Gene names	TM9SF4, KIAA0255
Domain Architecture
Description	Transmembrane 9 superfamily protein member 4.

CASC5_MOUSE
NC score	0.006536 (rank : 111)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	123	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

SACA1_MOUSE
NC score	0.006224 (rank : 112)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	123	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DA48	Gene names	Spaca1
Domain Architecture	No domain graphic available
Description	Sperm acrosome membrane-associated protein 1 precursor.

MRGX4_HUMAN
NC score	0.006221 (rank : 113)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	123	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LA9, Q3KNU3, Q3KNU4, Q502W0, Q8TDD6, Q8TDD7	Gene names	MRGPRX4, MRGX4, SNSR5, SNSR6
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member X4 (Sensory neuron- specific G-protein coupled receptor 5/6).

CLCN1_HUMAN
NC score	0.004994 (rank : 114)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	123	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

DRP2_HUMAN
NC score	0.004574 (rank : 115)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	123	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

BRE1A_MOUSE
NC score	0.003980 (rank : 116)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	123	Target Neighborhood Hits	1025	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

DHX29_HUMAN
NC score	0.003892 (rank : 117)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	123	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

BRE1A_HUMAN
NC score	0.003772 (rank : 118)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	123	Target Neighborhood Hits	1071	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

K0528_MOUSE
NC score	0.003631 (rank : 119)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	123	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

TA2R7_HUMAN
NC score	0.001413 (rank : 120)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	123	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYW3	Gene names	TAS2R7
Domain Architecture
Description	Taste receptor type 2 member 7 (T2R7) (Taste receptor family B member 4) (TRB4).

CASP_MOUSE
NC score	-0.001650 (rank : 121)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	123	Target Neighborhood Hits	1152	Shared Neighborhood Hits	12
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

MACF4_HUMAN
NC score	-0.002571 (rank : 122)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	123	Target Neighborhood Hits	1321	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

EEA1_HUMAN
NC score	-0.004084 (rank : 123)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	123	Target Neighborhood Hits	1796	Shared Neighborhood Hits	15
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

AKAP9_HUMAN
NC score	-0.004228 (rank : 124)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	123	Target Neighborhood Hits	1710	Shared Neighborhood Hits	14
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ACM2_HUMAN
NC score	-0.005660 (rank : 125)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	123	Target Neighborhood Hits	930	Shared Neighborhood Hits	2
SwissProt Accessions	P08172, Q9P1X9	Gene names	CHRM2
Domain Architecture
Description	Muscarinic acetylcholine receptor M2.