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Network neighborhood for query Sequence : CASC5_MOUSE

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CASC5_MOUSE
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CASC5_HUMAN
θ value	0 (rank : 1)	NC score	0.808324 (rank : 2)
Query Neighborhood Hits	70	Target Neighborhood Hits	376	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CASC5_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	70	Target Neighborhood Hits	70	Shared Neighborhood Hits	70
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

AF9_HUMAN
θ value	0.00509761 (rank : 3)	NC score	0.099203 (rank : 4)
Query Neighborhood Hits	70	Target Neighborhood Hits	202	Shared Neighborhood Hits	12
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

TENN_MOUSE
θ value	0.00869519 (rank : 4)	NC score	0.029726 (rank : 32)
Query Neighborhood Hits	70	Target Neighborhood Hits	484	Shared Neighborhood Hits	5
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

VEZA_HUMAN
θ value	0.0431538 (rank : 5)	NC score	0.100659 (rank : 3)
Query Neighborhood Hits	70	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HBM0, Q9H2F4, Q9H2U5, Q9NT70, Q9NVW0, Q9UF91	Gene names	VEZT
Domain Architecture	No domain graphic available
Description	Vezatin.

ANR11_HUMAN
θ value	0.0563607 (rank : 6)	NC score	0.039442 (rank : 18)
Query Neighborhood Hits	70	Target Neighborhood Hits	1289	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ACINU_MOUSE
θ value	0.163984 (rank : 7)	NC score	0.056773 (rank : 6)
Query Neighborhood Hits	70	Target Neighborhood Hits	712	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NEIL3_HUMAN
θ value	0.163984 (rank : 8)	NC score	0.059019 (rank : 5)
Query Neighborhood Hits	70	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

RAI14_MOUSE
θ value	0.163984 (rank : 9)	NC score	0.029228 (rank : 37)
Query Neighborhood Hits	70	Target Neighborhood Hits	1505	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

TRIPB_HUMAN
θ value	0.163984 (rank : 10)	NC score	0.048384 (rank : 10)
Query Neighborhood Hits	70	Target Neighborhood Hits	1587	Shared Neighborhood Hits	32
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

KMHN1_MOUSE
θ value	0.279714 (rank : 11)	NC score	0.042470 (rank : 15)
Query Neighborhood Hits	70	Target Neighborhood Hits	949	Shared Neighborhood Hits	27
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LUZP1_MOUSE
θ value	0.279714 (rank : 12)	NC score	0.051996 (rank : 8)
Query Neighborhood Hits	70	Target Neighborhood Hits	940	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MAP1A_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.047820 (rank : 11)
Query Neighborhood Hits	70	Target Neighborhood Hits	1626	Shared Neighborhood Hits	28
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SFRIP_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.050027 (rank : 9)
Query Neighborhood Hits	70	Target Neighborhood Hits	530	Shared Neighborhood Hits	17
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

ACOT1_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.024861 (rank : 43)
Query Neighborhood Hits	70	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	O55137, Q549A9	Gene names	Acot1, Cte1
Domain Architecture
Description	Acyl-coenzyme A thioesterase 1 (EC 3.1.2.2) (Acyl-CoA thioesterase 1) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (CTE-I).

ANR26_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.028070 (rank : 39)
Query Neighborhood Hits	70	Target Neighborhood Hits	1554	Shared Neighborhood Hits	27
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CR034_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.054139 (rank : 7)
Query Neighborhood Hits	70	Target Neighborhood Hits	538	Shared Neighborhood Hits	21
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

SYNG_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.041877 (rank : 16)
Query Neighborhood Hits	70	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

PIBF1_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.032610 (rank : 26)
Query Neighborhood Hits	70	Target Neighborhood Hits	1041	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

CPIN1_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.047022 (rank : 12)
Query Neighborhood Hits	70	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WTY4, Q3UJW5, Q8VC24, Q91W83	Gene names	Ciapin1
Domain Architecture	No domain graphic available
Description	Anamorsin (Cytokine-induced apoptosis inhibitor 1).

MLL3_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.020604 (rank : 49)
Query Neighborhood Hits	70	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PININ_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.045317 (rank : 13)
Query Neighborhood Hits	70	Target Neighborhood Hits	753	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

TPR_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.037667 (rank : 21)
Query Neighborhood Hits	70	Target Neighborhood Hits	1921	Shared Neighborhood Hits	37
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ENPP2_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.021983 (rank : 47)
Query Neighborhood Hits	70	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

EVC_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.038656 (rank : 20)
Query Neighborhood Hits	70	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	P57680	Gene names	Evc
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein homolog.

GAB2_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.035670 (rank : 23)
Query Neighborhood Hits	70	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

LHR2A_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.034526 (rank : 24)
Query Neighborhood Hits	70	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

SCN9A_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.012644 (rank : 63)
Query Neighborhood Hits	70	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

RP1_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.026707 (rank : 41)
Query Neighborhood Hits	70	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

ADDB_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.030062 (rank : 30)
Query Neighborhood Hits	70	Target Neighborhood Hits	574	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AHI1_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.014832 (rank : 61)
Query Neighborhood Hits	70	Target Neighborhood Hits	537	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AKA10_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.036443 (rank : 22)
Query Neighborhood Hits	70	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

CI084_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.038796 (rank : 19)
Query Neighborhood Hits	70	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VXU9, Q96M73	Gene names	C9orf84
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf84.

KINH_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.022891 (rank : 44)
Query Neighborhood Hits	70	Target Neighborhood Hits	1082	Shared Neighborhood Hits	25
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MAP1B_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.044558 (rank : 14)
Query Neighborhood Hits	70	Target Neighborhood Hits	977	Shared Neighborhood Hits	27
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RBBP6_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.031544 (rank : 29)
Query Neighborhood Hits	70	Target Neighborhood Hits	1014	Shared Neighborhood Hits	19
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TCF8_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.004905 (rank : 69)
Query Neighborhood Hits	70	Target Neighborhood Hits	1057	Shared Neighborhood Hits	11
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TLR2_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.012010 (rank : 64)
Query Neighborhood Hits	70	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

AKAP9_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.033882 (rank : 25)
Query Neighborhood Hits	70	Target Neighborhood Hits	1710	Shared Neighborhood Hits	32
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ANGP2_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.022685 (rank : 45)
Query Neighborhood Hits	70	Target Neighborhood Hits	397	Shared Neighborhood Hits	18
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

APBA3_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.017456 (rank : 52)
Query Neighborhood Hits	70	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

MYCB2_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.021691 (rank : 48)
Query Neighborhood Hits	70	Target Neighborhood Hits	390	Shared Neighborhood Hits	11
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NUF2_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.032419 (rank : 28)
Query Neighborhood Hits	70	Target Neighborhood Hits	661	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

ADA12_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.007084 (rank : 66)
Query Neighborhood Hits	70	Target Neighborhood Hits	474	Shared Neighborhood Hits	4
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

GAB2_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.029969 (rank : 31)
Query Neighborhood Hits	70	Target Neighborhood Hits	220	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

NEUT_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.032597 (rank : 27)
Query Neighborhood Hits	70	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3P9	Gene names	Nts
Domain Architecture
Description	Neurotensin/neuromedin N precursor [Contains: Large neuromedin N (NmN- 125); Neuromedin N (NmN) (NN); Neurotensin (NT); Tail peptide].

PININ_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.040867 (rank : 17)
Query Neighborhood Hits	70	Target Neighborhood Hits	777	Shared Neighborhood Hits	24
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

CCD21_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.028041 (rank : 40)
Query Neighborhood Hits	70	Target Neighborhood Hits	1228	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

COE3_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.016912 (rank : 56)
Query Neighborhood Hits	70	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

COE3_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.016928 (rank : 55)
Query Neighborhood Hits	70	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

KINH_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.022072 (rank : 46)
Query Neighborhood Hits	70	Target Neighborhood Hits	1231	Shared Neighborhood Hits	28
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

LAMB2_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.008042 (rank : 65)
Query Neighborhood Hits	70	Target Neighborhood Hits	722	Shared Neighborhood Hits	11
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

NRIP1_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.019775 (rank : 50)
Query Neighborhood Hits	70	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P48552, Q8IWE8	Gene names	NRIP1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

AKA10_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.029259 (rank : 35)
Query Neighborhood Hits	70	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

CD5R1_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.016678 (rank : 57)
Query Neighborhood Hits	70	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q15078	Gene names	CDK5R1, CDK5R, NCK5A
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (TPKII regulatory subunit) (p23) (p25) (p35) [Contains: Cyclin-dependent kinase 5 activator 1, p35; Cyclin- dependent kinase 5 activator 1, p25].

DPOLN_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.017241 (rank : 54)
Query Neighborhood Hits	70	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5Q5, Q4TTW4, Q6ZNF4	Gene names	POLN
Domain Architecture	No domain graphic available
Description	DNA polymerase nu (EC 2.7.7.7).

GCC2_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.029252 (rank : 36)
Query Neighborhood Hits	70	Target Neighborhood Hits	1619	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

KIF3A_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.015609 (rank : 59)
Query Neighborhood Hits	70	Target Neighborhood Hits	715	Shared Neighborhood Hits	19
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

LYPL1_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.018243 (rank : 51)
Query Neighborhood Hits	70	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VWZ2, Q5VWZ3, Q7Z4A3, Q96AV0	Gene names	LYPLAL1
Domain Architecture	No domain graphic available
Description	Lysophospholipase-like protein 1 (EC 3.1.2.-).

MAT1_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.029214 (rank : 38)
Query Neighborhood Hits	70	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.029393 (rank : 34)
Query Neighborhood Hits	70	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MPH6_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.025152 (rank : 42)
Query Neighborhood Hits	70	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q99547	Gene names	MPHOSPH6, MPP6
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 6.

MYST3_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.015765 (rank : 58)
Query Neighborhood Hits	70	Target Neighborhood Hits	772	Shared Neighborhood Hits	18
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

UACA_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.029421 (rank : 33)
Query Neighborhood Hits	70	Target Neighborhood Hits	1622	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ABCAA_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.006536 (rank : 67)
Query Neighborhood Hits	70	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

CDC5L_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.017334 (rank : 53)
Query Neighborhood Hits	70	Target Neighborhood Hits	205	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

EMR3_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.004370 (rank : 70)
Query Neighborhood Hits	70	Target Neighborhood Hits	245	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

GTSE1_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.014867 (rank : 60)
Query Neighborhood Hits	70	Target Neighborhood Hits	245	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

SYTL5_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.006100 (rank : 68)
Query Neighborhood Hits	70	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

ZC3H5_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.014124 (rank : 62)
Query Neighborhood Hits	70	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

Hits sorted by NC score

CASC5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	70	Target Neighborhood Hits	70	Shared Neighborhood Hits	70
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

CASC5_HUMAN
NC score	0.808324 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	70	Target Neighborhood Hits	376	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

VEZA_HUMAN
NC score	0.100659 (rank : 3)	θ value	0.0431538 (rank : 5)
Query Neighborhood Hits	70	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HBM0, Q9H2F4, Q9H2U5, Q9NT70, Q9NVW0, Q9UF91	Gene names	VEZT
Domain Architecture	No domain graphic available
Description	Vezatin.

AF9_HUMAN
NC score	0.099203 (rank : 4)	θ value	0.00509761 (rank : 3)
Query Neighborhood Hits	70	Target Neighborhood Hits	202	Shared Neighborhood Hits	12
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

NEIL3_HUMAN
NC score	0.059019 (rank : 5)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	70	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

ACINU_MOUSE
NC score	0.056773 (rank : 6)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	70	Target Neighborhood Hits	712	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CR034_HUMAN
NC score	0.054139 (rank : 7)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	70	Target Neighborhood Hits	538	Shared Neighborhood Hits	21
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

LUZP1_MOUSE
NC score	0.051996 (rank : 8)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	70	Target Neighborhood Hits	940	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

SFRIP_HUMAN
NC score	0.050027 (rank : 9)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	70	Target Neighborhood Hits	530	Shared Neighborhood Hits	17
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

TRIPB_HUMAN
NC score	0.048384 (rank : 10)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	70	Target Neighborhood Hits	1587	Shared Neighborhood Hits	32
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

MAP1A_HUMAN
NC score	0.047820 (rank : 11)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	70	Target Neighborhood Hits	1626	Shared Neighborhood Hits	28
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CPIN1_MOUSE
NC score	0.047022 (rank : 12)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	70	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WTY4, Q3UJW5, Q8VC24, Q91W83	Gene names	Ciapin1
Domain Architecture	No domain graphic available
Description	Anamorsin (Cytokine-induced apoptosis inhibitor 1).

PININ_HUMAN
NC score	0.045317 (rank : 13)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	70	Target Neighborhood Hits	753	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

MAP1B_MOUSE
NC score	0.044558 (rank : 14)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	70	Target Neighborhood Hits	977	Shared Neighborhood Hits	27
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

KMHN1_MOUSE
NC score	0.042470 (rank : 15)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	70	Target Neighborhood Hits	949	Shared Neighborhood Hits	27
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

SYNG_MOUSE
NC score	0.041877 (rank : 16)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	70	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

PININ_MOUSE
NC score	0.040867 (rank : 17)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	70	Target Neighborhood Hits	777	Shared Neighborhood Hits	24
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

ANR11_HUMAN
NC score	0.039442 (rank : 18)	θ value	0.0563607 (rank : 6)
Query Neighborhood Hits	70	Target Neighborhood Hits	1289	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CI084_HUMAN
NC score	0.038796 (rank : 19)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	70	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VXU9, Q96M73	Gene names	C9orf84
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf84.

EVC_MOUSE
NC score	0.038656 (rank : 20)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	70	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	P57680	Gene names	Evc
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein homolog.

TPR_HUMAN
NC score	0.037667 (rank : 21)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	70	Target Neighborhood Hits	1921	Shared Neighborhood Hits	37
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

AKA10_MOUSE
NC score	0.036443 (rank : 22)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	70	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

GAB2_HUMAN
NC score	0.035670 (rank : 23)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	70	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

LHR2A_HUMAN
NC score	0.034526 (rank : 24)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	70	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

AKAP9_HUMAN
NC score	0.033882 (rank : 25)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	70	Target Neighborhood Hits	1710	Shared Neighborhood Hits	32
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

PIBF1_HUMAN
NC score	0.032610 (rank : 26)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	70	Target Neighborhood Hits	1041	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

NEUT_MOUSE
NC score	0.032597 (rank : 27)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	70	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3P9	Gene names	Nts
Domain Architecture
Description	Neurotensin/neuromedin N precursor [Contains: Large neuromedin N (NmN- 125); Neuromedin N (NmN) (NN); Neurotensin (NT); Tail peptide].

NUF2_HUMAN
NC score	0.032419 (rank : 28)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	70	Target Neighborhood Hits	661	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

RBBP6_MOUSE
NC score	0.031544 (rank : 29)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	70	Target Neighborhood Hits	1014	Shared Neighborhood Hits	19
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

ADDB_MOUSE
NC score	0.030062 (rank : 30)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	70	Target Neighborhood Hits	574	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

GAB2_MOUSE
NC score	0.029969 (rank : 31)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	70	Target Neighborhood Hits	220	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

TENN_MOUSE
NC score	0.029726 (rank : 32)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	70	Target Neighborhood Hits	484	Shared Neighborhood Hits	5
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

UACA_HUMAN
NC score	0.029421 (rank : 33)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	70	Target Neighborhood Hits	1622	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

MAT1_MOUSE
NC score	0.029393 (rank : 34)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	70	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

AKA10_HUMAN
NC score	0.029259 (rank : 35)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	70	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

GCC2_MOUSE
NC score	0.029252 (rank : 36)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	70	Target Neighborhood Hits	1619	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

RAI14_MOUSE
NC score	0.029228 (rank : 37)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	70	Target Neighborhood Hits	1505	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

MAT1_HUMAN
NC score	0.029214 (rank : 38)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	70	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

ANR26_MOUSE
NC score	0.028070 (rank : 39)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	70	Target Neighborhood Hits	1554	Shared Neighborhood Hits	27
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CCD21_HUMAN
NC score	0.028041 (rank : 40)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	70	Target Neighborhood Hits	1228	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

RP1_MOUSE
NC score	0.026707 (rank : 41)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	70	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

MPH6_HUMAN
NC score	0.025152 (rank : 42)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	70	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q99547	Gene names	MPHOSPH6, MPP6
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 6.

ACOT1_MOUSE
NC score	0.024861 (rank : 43)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	70	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	O55137, Q549A9	Gene names	Acot1, Cte1
Domain Architecture
Description	Acyl-coenzyme A thioesterase 1 (EC 3.1.2.2) (Acyl-CoA thioesterase 1) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (CTE-I).

KINH_MOUSE
NC score	0.022891 (rank : 44)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	70	Target Neighborhood Hits	1082	Shared Neighborhood Hits	25
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

ANGP2_MOUSE
NC score	0.022685 (rank : 45)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	70	Target Neighborhood Hits	397	Shared Neighborhood Hits	18
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

KINH_HUMAN
NC score	0.022072 (rank : 46)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	70	Target Neighborhood Hits	1231	Shared Neighborhood Hits	28
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

ENPP2_HUMAN
NC score	0.021983 (rank : 47)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	70	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

MYCB2_HUMAN
NC score	0.021691 (rank : 48)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	70	Target Neighborhood Hits	390	Shared Neighborhood Hits	11
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MLL3_HUMAN
NC score	0.020604 (rank : 49)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	70	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NRIP1_HUMAN
NC score	0.019775 (rank : 50)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	70	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P48552, Q8IWE8	Gene names	NRIP1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

LYPL1_HUMAN
NC score	0.018243 (rank : 51)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	70	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VWZ2, Q5VWZ3, Q7Z4A3, Q96AV0	Gene names	LYPLAL1
Domain Architecture	No domain graphic available
Description	Lysophospholipase-like protein 1 (EC 3.1.2.-).

APBA3_MOUSE
NC score	0.017456 (rank : 52)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	70	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

CDC5L_MOUSE
NC score	0.017334 (rank : 53)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	70	Target Neighborhood Hits	205	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

DPOLN_HUMAN
NC score	0.017241 (rank : 54)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	70	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5Q5, Q4TTW4, Q6ZNF4	Gene names	POLN
Domain Architecture	No domain graphic available
Description	DNA polymerase nu (EC 2.7.7.7).

COE3_MOUSE
NC score	0.016928 (rank : 55)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	70	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

COE3_HUMAN
NC score	0.016912 (rank : 56)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	70	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

CD5R1_HUMAN
NC score	0.016678 (rank : 57)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	70	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q15078	Gene names	CDK5R1, CDK5R, NCK5A
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 1 precursor (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (Tau protein kinase II 23 kDa subunit) (TPKII regulatory subunit) (p23) (p25) (p35) [Contains: Cyclin-dependent kinase 5 activator 1, p35; Cyclin- dependent kinase 5 activator 1, p25].

MYST3_HUMAN
NC score	0.015765 (rank : 58)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	70	Target Neighborhood Hits	772	Shared Neighborhood Hits	18
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

KIF3A_MOUSE
NC score	0.015609 (rank : 59)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	70	Target Neighborhood Hits	715	Shared Neighborhood Hits	19
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

GTSE1_MOUSE
NC score	0.014867 (rank : 60)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	70	Target Neighborhood Hits	245	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

AHI1_HUMAN
NC score	0.014832 (rank : 61)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	70	Target Neighborhood Hits	537	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ZC3H5_MOUSE
NC score	0.014124 (rank : 62)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	70	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

SCN9A_HUMAN
NC score	0.012644 (rank : 63)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	70	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

TLR2_HUMAN
NC score	0.012010 (rank : 64)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	70	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

LAMB2_MOUSE
NC score	0.008042 (rank : 65)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	70	Target Neighborhood Hits	722	Shared Neighborhood Hits	11
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

ADA12_MOUSE
NC score	0.007084 (rank : 66)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	70	Target Neighborhood Hits	474	Shared Neighborhood Hits	4
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ABCAA_HUMAN
NC score	0.006536 (rank : 67)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	70	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

SYTL5_MOUSE
NC score	0.006100 (rank : 68)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	70	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

TCF8_HUMAN
NC score	0.004905 (rank : 69)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	70	Target Neighborhood Hits	1057	Shared Neighborhood Hits	11
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

EMR3_HUMAN
NC score	0.004370 (rank : 70)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	70	Target Neighborhood Hits	245	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).