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Network neighborhood for query Sequence : CLCN1_HUMAN

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CLCN1_HUMAN
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CLCN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CLCN1_MOUSE
θ value	0 (rank : 2)	NC score	0.994108 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	61	Shared Neighborhood Hits	29
SwissProt Accessions	Q64347	Gene names	Clcn1, Clc1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CLCN2_HUMAN
θ value	0 (rank : 3)	NC score	0.985702 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P51788, O14864, Q8WU13	Gene names	CLCN2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CLCN2_MOUSE
θ value	0 (rank : 4)	NC score	0.985828 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0A1, Q9WUJ9	Gene names	Clcn2, Clc2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CLCKA_HUMAN
θ value	1.02419e-128 (rank : 5)	NC score	0.953751 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51800, Q7Z6D1, Q86VT1	Gene names	CLCNKA
Domain Architecture
Description	Chloride channel protein ClC-Ka (Chloride channel Ka) (ClC-K1).

CLCKA_MOUSE
θ value	2.28167e-128 (rank : 6)	NC score	0.959478 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUB7, Q6UB69, Q8JZU7	Gene names	Clcnka, Clcnk1
Domain Architecture	No domain graphic available
Description	Chloride channel protein ClC-Ka (Chloride channel Ka) (ClC-K1).

CLCKB_HUMAN
θ value	3.64273e-126 (rank : 7)	NC score	0.956938 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51801	Gene names	CLCNKB
Domain Architecture
Description	Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2).

CLCKB_MOUSE
θ value	7.10925e-122 (rank : 8)	NC score	0.954668 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUB6, Q8VCF8	Gene names	Clcnkb, Clckb, Clcnk1l
Domain Architecture	No domain graphic available
Description	Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2).

CLCN5_MOUSE
θ value	2.49495e-50 (rank : 9)	NC score	0.835161 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVD4	Gene names	Clcn5, Clc5
Domain Architecture
Description	Chloride channel protein 5 (ClC-5).

CLCN5_HUMAN
θ value	3.2585e-50 (rank : 10)	NC score	0.832507 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P51795, Q5JQD5	Gene names	CLCN5, CLCK2
Domain Architecture
Description	Chloride channel protein 5 (ClC-5).

CLCN4_HUMAN
θ value	1.51363e-47 (rank : 11)	NC score	0.826717 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51793, Q9UBU1	Gene names	CLCN4
Domain Architecture
Description	Chloride channel protein 4 (ClC-4).

CLCN3_HUMAN
θ value	2.85459e-46 (rank : 12)	NC score	0.820868 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	P51790, O14918, Q86Z21	Gene names	CLCN3
Domain Architecture
Description	Chloride channel protein 3 (ClC-3).

CLCN3_MOUSE
θ value	6.35935e-46 (rank : 13)	NC score	0.821632 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	P51791	Gene names	Clcn3, Clc3
Domain Architecture
Description	Chloride channel protein 3 (ClC-3).

CLCN4_MOUSE
θ value	8.30557e-46 (rank : 14)	NC score	0.822204 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q61418	Gene names	Clcn4, Clc4, Clcn4-2
Domain Architecture
Description	Chloride channel protein 4 (ClC-4).

CLCN7_HUMAN
θ value	1.6774e-38 (rank : 15)	NC score	0.826228 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P51798, Q9NYX5	Gene names	CLCN7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

CLCN7_MOUSE
θ value	4.88048e-38 (rank : 16)	NC score	0.825609 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	O70496	Gene names	Clcn7, Clc7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

CLCN6_HUMAN
θ value	3.3877e-31 (rank : 17)	NC score	0.780598 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P51797, O60818, O60819, O60820, O60821, P78520, P78521, Q5SNW2, Q5SNW3, Q5SNX1, Q5SNX2, Q5SNX3, Q99427, Q99428, Q99429	Gene names	CLCN6, KIAA0046
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

CLCN6_MOUSE
θ value	7.54701e-31 (rank : 18)	NC score	0.774450 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	O35454	Gene names	Clcn6, Clc6
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

SRRM2_MOUSE
θ value	0.0148317 (rank : 19)	NC score	0.032572 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SPEG_HUMAN
θ value	0.0563607 (rank : 20)	NC score	0.005393 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	1762	Shared Neighborhood Hits	30
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

NEK11_HUMAN
θ value	0.125558 (rank : 21)	NC score	0.003272 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	1043	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

CEND1_MOUSE
θ value	0.163984 (rank : 22)	NC score	0.023890 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	260	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
θ value	0.279714 (rank : 23)	NC score	0.023255 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

LCP2_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.029269 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	531	Shared Neighborhood Hits	24
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PTN22_MOUSE
θ value	0.279714 (rank : 25)	NC score	0.010210 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

SF01_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.033192 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	287	Shared Neighborhood Hits	10
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	0.365318 (rank : 27)	NC score	0.034698 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

MEFV_MOUSE
θ value	0.47712 (rank : 28)	NC score	0.016120 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

BPTF_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.015045 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	786	Shared Neighborhood Hits	15
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

AUTS2_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.027250 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

MDC1_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.016873 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	1446	Shared Neighborhood Hits	32
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

BASP_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.023828 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	260	Shared Neighborhood Hits	13
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

LPIN3_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.012936 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

DRAP1_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.023374 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q14919, Q13448	Gene names	DRAP1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

LTB1L_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.011194 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	553	Shared Neighborhood Hits	9
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.011192 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	502	Shared Neighborhood Hits	8
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

RGS3_MOUSE
θ value	1.38821 (rank : 37)	NC score	0.017243 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	1621	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SRRM2_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.031663 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ABCAA_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.004994 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

PRB3_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.014394 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	318	Shared Neighborhood Hits	16
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

ATS19_MOUSE
θ value	2.36792 (rank : 41)	NC score	0.003619 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

BRPF3_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.009000 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CGRE1_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.014968 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

FA47A_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.018492 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	451	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

HTF4_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.010892 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

CML2_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.000615 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	724	Shared Neighborhood Hits	3
SwissProt Accessions	Q99527, O00143, O43494, Q13631, Q96F42, Q99981	Gene names	GPR30, CEPR, CMKRL2, DRY12
Domain Architecture
Description	Chemokine receptor-like 2 (G-protein coupled receptor 30) (IL8-related receptor DRY12) (Flow-induced endothelial G-protein coupled receptor) (FEG-1) (GPCR-BR).

GON4L_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.011861 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	555	Shared Neighborhood Hits	14
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LCP2_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.023553 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	177	Shared Neighborhood Hits	8
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

TENS1_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.012876 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	400	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TULP4_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.012273 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

JPH1_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.006919 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ET80, Q9EQZ3	Gene names	Jph1, Jp1
Domain Architecture
Description	Junctophilin-1 (Junctophilin type 1) (JP-1).

K0310_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.016904 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	420	Shared Neighborhood Hits	16
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

M3K11_HUMAN
θ value	4.03905 (rank : 53)	NC score	-0.001163 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	1136	Shared Neighborhood Hits	11
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

NCA12_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.002485 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	437	Shared Neighborhood Hits	3
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

PDXL2_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.013190 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

PRGC2_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.012902 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	272	Shared Neighborhood Hits	13
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

PRP1_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.011725 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SO2A1_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.014837 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

ST2B1_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.005612 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ATX1_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.012648 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	264	Shared Neighborhood Hits	13
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

FOXJ3_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.002812 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

MLL4_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.011977 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	722	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MOR2A_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.007364 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	220	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

PRB4S_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.011090 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	330	Shared Neighborhood Hits	13
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

RFIP1_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.010877 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SF3A2_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.011884 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

K1802_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.007003 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	1596	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LTB1L_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.008905 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	514	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.008931 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	479	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MLL2_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.008163 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	1788	Shared Neighborhood Hits	33
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.010567 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	1399	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NUP98_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.011515 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	P52948, Q8IUT2, Q8WYB0, Q96E54, Q9H3Q4, Q9NT02, Q9UF57, Q9UHX0, Q9Y6J4, Q9Y6J5	Gene names	NUP98
Domain Architecture
Description	Nuclear pore complex protein Nup98-Nup96 precursor [Contains: Nuclear pore complex protein Nup98 (Nucleoporin Nup98) (98 kDa nucleoporin); Nuclear pore complex protein Nup96 (Nucleoporin Nup96) (96 kDa nucleoporin)].

PPM1F_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.006898 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P49593, Q96PM2	Gene names	PPM1F, KIAA0015, POPX2
Domain Architecture
Description	Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein phosphatase 1F).

PRP5_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.016705 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPE_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.029141 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	44	Shared Neighborhood Hits	1
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

SPAG5_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.002439 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	625	Shared Neighborhood Hits	5
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

CO6A3_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.001901 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	317	Shared Neighborhood Hits	8
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

EPN3_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.004963 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

FMN2_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.006307 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	484	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

PKHA2_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.006669 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PTN23_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.004502 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	646	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RAI1_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.010999 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	344	Shared Neighborhood Hits	19
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RIMB1_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.002730 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	1479	Shared Neighborhood Hits	21
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SF3A1_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.008039 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SOS1_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.004401 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

TATD2_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.010435 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

TLE2_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.001377 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

TMAP1_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.013537 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZH7, Q8C6F8	Gene names	Tmap1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

ZN687_MOUSE
θ value	8.99809 (rank : 89)	NC score	-0.001528 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	913	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

Hits sorted by NC score

CLCN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CLCN1_MOUSE
NC score	0.994108 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	61	Shared Neighborhood Hits	29
SwissProt Accessions	Q64347	Gene names	Clcn1, Clc1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

CLCN2_MOUSE
NC score	0.985828 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0A1, Q9WUJ9	Gene names	Clcn2, Clc2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CLCN2_HUMAN
NC score	0.985702 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P51788, O14864, Q8WU13	Gene names	CLCN2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CLCKA_MOUSE
NC score	0.959478 (rank : 5)	θ value	2.28167e-128 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUB7, Q6UB69, Q8JZU7	Gene names	Clcnka, Clcnk1
Domain Architecture	No domain graphic available
Description	Chloride channel protein ClC-Ka (Chloride channel Ka) (ClC-K1).

CLCKB_HUMAN
NC score	0.956938 (rank : 6)	θ value	3.64273e-126 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51801	Gene names	CLCNKB
Domain Architecture
Description	Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2).

CLCKB_MOUSE
NC score	0.954668 (rank : 7)	θ value	7.10925e-122 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUB6, Q8VCF8	Gene names	Clcnkb, Clckb, Clcnk1l
Domain Architecture	No domain graphic available
Description	Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2).

CLCKA_HUMAN
NC score	0.953751 (rank : 8)	θ value	1.02419e-128 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51800, Q7Z6D1, Q86VT1	Gene names	CLCNKA
Domain Architecture
Description	Chloride channel protein ClC-Ka (Chloride channel Ka) (ClC-K1).

CLCN5_MOUSE
NC score	0.835161 (rank : 9)	θ value	2.49495e-50 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVD4	Gene names	Clcn5, Clc5
Domain Architecture
Description	Chloride channel protein 5 (ClC-5).

CLCN5_HUMAN
NC score	0.832507 (rank : 10)	θ value	3.2585e-50 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P51795, Q5JQD5	Gene names	CLCN5, CLCK2
Domain Architecture
Description	Chloride channel protein 5 (ClC-5).

CLCN4_HUMAN
NC score	0.826717 (rank : 11)	θ value	1.51363e-47 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	P51793, Q9UBU1	Gene names	CLCN4
Domain Architecture
Description	Chloride channel protein 4 (ClC-4).

CLCN7_HUMAN
NC score	0.826228 (rank : 12)	θ value	1.6774e-38 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P51798, Q9NYX5	Gene names	CLCN7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

CLCN7_MOUSE
NC score	0.825609 (rank : 13)	θ value	4.88048e-38 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	O70496	Gene names	Clcn7, Clc7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

CLCN4_MOUSE
NC score	0.822204 (rank : 14)	θ value	8.30557e-46 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q61418	Gene names	Clcn4, Clc4, Clcn4-2
Domain Architecture
Description	Chloride channel protein 4 (ClC-4).

CLCN3_MOUSE
NC score	0.821632 (rank : 15)	θ value	6.35935e-46 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	P51791	Gene names	Clcn3, Clc3
Domain Architecture
Description	Chloride channel protein 3 (ClC-3).

CLCN3_HUMAN
NC score	0.820868 (rank : 16)	θ value	2.85459e-46 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	P51790, O14918, Q86Z21	Gene names	CLCN3
Domain Architecture
Description	Chloride channel protein 3 (ClC-3).

CLCN6_HUMAN
NC score	0.780598 (rank : 17)	θ value	3.3877e-31 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P51797, O60818, O60819, O60820, O60821, P78520, P78521, Q5SNW2, Q5SNW3, Q5SNX1, Q5SNX2, Q5SNX3, Q99427, Q99428, Q99429	Gene names	CLCN6, KIAA0046
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

CLCN6_MOUSE
NC score	0.774450 (rank : 18)	θ value	7.54701e-31 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	O35454	Gene names	Clcn6, Clc6
Domain Architecture
Description	Chloride channel protein 6 (ClC-6).

SF01_MOUSE
NC score	0.034698 (rank : 19)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF01_HUMAN
NC score	0.033192 (rank : 20)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	287	Shared Neighborhood Hits	10
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SRRM2_MOUSE
NC score	0.032572 (rank : 21)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM2_HUMAN
NC score	0.031663 (rank : 22)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

LCP2_HUMAN
NC score	0.029269 (rank : 23)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	531	Shared Neighborhood Hits	24
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PRPE_HUMAN
NC score	0.029141 (rank : 24)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	44	Shared Neighborhood Hits	1
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

AUTS2_HUMAN
NC score	0.027250 (rank : 25)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

CEND1_MOUSE
NC score	0.023890 (rank : 26)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	260	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

BASP_MOUSE
NC score	0.023828 (rank : 27)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	260	Shared Neighborhood Hits	13
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

LCP2_MOUSE
NC score	0.023553 (rank : 28)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	177	Shared Neighborhood Hits	8
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

DRAP1_HUMAN
NC score	0.023374 (rank : 29)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q14919, Q13448	Gene names	DRAP1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

CEND1_HUMAN
NC score	0.023255 (rank : 30)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

FA47A_HUMAN
NC score	0.018492 (rank : 31)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	451	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

RGS3_MOUSE
NC score	0.017243 (rank : 32)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	1621	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

K0310_HUMAN
NC score	0.016904 (rank : 33)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	420	Shared Neighborhood Hits	16
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MDC1_HUMAN
NC score	0.016873 (rank : 34)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	1446	Shared Neighborhood Hits	32
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PRP5_HUMAN
NC score	0.016705 (rank : 35)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

MEFV_MOUSE
NC score	0.016120 (rank : 36)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

BPTF_HUMAN
NC score	0.015045 (rank : 37)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	786	Shared Neighborhood Hits	15
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CGRE1_HUMAN
NC score	0.014968 (rank : 38)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

SO2A1_MOUSE
NC score	0.014837 (rank : 39)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

PRB3_HUMAN
NC score	0.014394 (rank : 40)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	318	Shared Neighborhood Hits	16
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

TMAP1_MOUSE
NC score	0.013537 (rank : 41)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZH7, Q8C6F8	Gene names	Tmap1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

PDXL2_HUMAN
NC score	0.013190 (rank : 42)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

LPIN3_HUMAN
NC score	0.012936 (rank : 43)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

PRGC2_HUMAN
NC score	0.012902 (rank : 44)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	272	Shared Neighborhood Hits	13
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

TENS1_HUMAN
NC score	0.012876 (rank : 45)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	400	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

ATX1_MOUSE
NC score	0.012648 (rank : 46)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	264	Shared Neighborhood Hits	13
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

TULP4_MOUSE
NC score	0.012273 (rank : 47)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

MLL4_HUMAN
NC score	0.011977 (rank : 48)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	722	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SF3A2_HUMAN
NC score	0.011884 (rank : 49)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

GON4L_HUMAN
NC score	0.011861 (rank : 50)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	555	Shared Neighborhood Hits	14
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

PRP1_HUMAN
NC score	0.011725 (rank : 51)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

NUP98_HUMAN
NC score	0.011515 (rank : 52)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	P52948, Q8IUT2, Q8WYB0, Q96E54, Q9H3Q4, Q9NT02, Q9UF57, Q9UHX0, Q9Y6J4, Q9Y6J5	Gene names	NUP98
Domain Architecture
Description	Nuclear pore complex protein Nup98-Nup96 precursor [Contains: Nuclear pore complex protein Nup98 (Nucleoporin Nup98) (98 kDa nucleoporin); Nuclear pore complex protein Nup96 (Nucleoporin Nup96) (96 kDa nucleoporin)].

LTB1L_HUMAN
NC score	0.011194 (rank : 53)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	553	Shared Neighborhood Hits	9
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.011192 (rank : 54)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	502	Shared Neighborhood Hits	8
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PRB4S_HUMAN
NC score	0.011090 (rank : 55)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	330	Shared Neighborhood Hits	13
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

RAI1_MOUSE
NC score	0.010999 (rank : 56)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	344	Shared Neighborhood Hits	19
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

HTF4_MOUSE
NC score	0.010892 (rank : 57)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

RFIP1_HUMAN
NC score	0.010877 (rank : 58)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

MLL3_MOUSE
NC score	0.010567 (rank : 59)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	1399	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TATD2_HUMAN
NC score	0.010435 (rank : 60)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

PTN22_MOUSE
NC score	0.010210 (rank : 61)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

BRPF3_HUMAN
NC score	0.009000 (rank : 62)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

LTB1S_MOUSE
NC score	0.008931 (rank : 63)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	479	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.008905 (rank : 64)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	514	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MLL2_HUMAN
NC score	0.008163 (rank : 65)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	1788	Shared Neighborhood Hits	33
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SF3A1_HUMAN
NC score	0.008039 (rank : 66)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

MOR2A_MOUSE
NC score	0.007364 (rank : 67)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	220	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

K1802_MOUSE
NC score	0.007003 (rank : 68)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	1596	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

JPH1_MOUSE
NC score	0.006919 (rank : 69)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ET80, Q9EQZ3	Gene names	Jph1, Jp1
Domain Architecture
Description	Junctophilin-1 (Junctophilin type 1) (JP-1).

PPM1F_HUMAN
NC score	0.006898 (rank : 70)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P49593, Q96PM2	Gene names	PPM1F, KIAA0015, POPX2
Domain Architecture
Description	Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein phosphatase 1F).

PKHA2_MOUSE
NC score	0.006669 (rank : 71)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

FMN2_HUMAN
NC score	0.006307 (rank : 72)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	484	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

ST2B1_HUMAN
NC score	0.005612 (rank : 73)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

SPEG_HUMAN
NC score	0.005393 (rank : 74)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	1762	Shared Neighborhood Hits	30
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ABCAA_HUMAN
NC score	0.004994 (rank : 75)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

EPN3_HUMAN
NC score	0.004963 (rank : 76)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

PTN23_HUMAN
NC score	0.004502 (rank : 77)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	646	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SOS1_MOUSE
NC score	0.004401 (rank : 78)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

ATS19_MOUSE
NC score	0.003619 (rank : 79)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

NEK11_HUMAN
NC score	0.003272 (rank : 80)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	1043	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

FOXJ3_MOUSE
NC score	0.002812 (rank : 81)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

RIMB1_HUMAN
NC score	0.002730 (rank : 82)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	1479	Shared Neighborhood Hits	21
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NCA12_HUMAN
NC score	0.002485 (rank : 83)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	437	Shared Neighborhood Hits	3
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

SPAG5_HUMAN
NC score	0.002439 (rank : 84)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	625	Shared Neighborhood Hits	5
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

CO6A3_HUMAN
NC score	0.001901 (rank : 85)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	317	Shared Neighborhood Hits	8
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

TLE2_HUMAN
NC score	0.001377 (rank : 86)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

CML2_HUMAN
NC score	0.000615 (rank : 87)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	724	Shared Neighborhood Hits	3
SwissProt Accessions	Q99527, O00143, O43494, Q13631, Q96F42, Q99981	Gene names	GPR30, CEPR, CMKRL2, DRY12
Domain Architecture
Description	Chemokine receptor-like 2 (G-protein coupled receptor 30) (IL8-related receptor DRY12) (Flow-induced endothelial G-protein coupled receptor) (FEG-1) (GPCR-BR).

M3K11_HUMAN
NC score	-0.001163 (rank : 88)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	1136	Shared Neighborhood Hits	11
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

ZN687_MOUSE
NC score	-0.001528 (rank : 89)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	913	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.